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Issue 29159 #29186

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Nov 12, 2024
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41 changes: 24 additions & 17 deletions src/ontology/go-edit.obo
Original file line number Diff line number Diff line change
Expand Up @@ -119667,15 +119667,12 @@ is_obsolete: true

[Term]
id: GO:0016172
name: obsolete antifreeze activity
name: antifreeze activity
namespace: molecular_function
def: "OBSOLETE. Inhibits the formation of ice crystals in organismal fluid (e.g. blood) at below freezing exogenous temperatures." [GOC:jl]
comment: This term was made obsolete because it refers to a biological process.
synonym: "antifreeze activity" EXACT []
is_obsolete: true
consider: GO:0042309
consider: GO:0050825
consider: GO:0050826
def: "Inhibits the growth and recrystallization of ice crystals, thereby lowering the freezing point of water and preventing cellular damage at subzero temperatures. This activity is observed in various cold-adapted organisms, including certain fish, insects, and plants, and contributes to survival in extreme cold environments by stabilizing supercooled liquid states." [GOC:cjm, InterPro:IPR000104]
comment: Note that this term was reinstated from obsolete.
is_a: GO:0050825 ! ice binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29149" xsd:anyURI

[Term]
id: GO:0016173
Expand Down Expand Up @@ -147852,14 +147849,13 @@ replaced_by: GO:0046689

[Term]
id: GO:0019833
name: obsolete ice nucleation activity
name: ice nucleation activity
namespace: molecular_function
def: "OBSOLETE. Catalysis of the formation of ice crystals in extracellular fluid at relatively high temperatures (up to -2 degrees C) to protect the organism from damage by intracellular ice formation. Ice nucleation proteins function by binding an ice crystal and then encouraging it to form larger crystals. Ice nucleation is a chemical process but these proteins can positively regulate it. There are two different uses of ice nucleation proteins: bacteria secrete them extracellularly to cause a host organism's cells to freeze and die, and fish use them to protect themselves from intracellular ice formation." [GOC:ai, GOC:jl]
comment: This term was made obsolete because it represents a biological process.
synonym: "ice nucleation activity" EXACT []
is_obsolete: true
consider: GO:0042309
consider: GO:0050825
def: "Catalysis of the formation of ice crystals in extracellular fluid at relatively high temperatures (up to -2 degrees Celsius) to protect the organism from damage by intracellular ice formation. This process is commonly found in certain bacteria, such as Pseudomonas syringae, and plays roles in environmental adaptation and plant pathogenesis." [GOC:cjm, PMID:35551271, UniProt:KW-0387]
comment: Note that this term was reinstated from obsolete.
xref: TC:9.B.133.1.1
is_a: GO:0050825 ! ice binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29149" xsd:anyURI

[Term]
id: GO:0019834
Expand Down Expand Up @@ -317661,9 +317657,7 @@ id: GO:0050825
name: ice binding
namespace: molecular_function
def: "Binding to ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal." [GOC:curators]
synonym: "antifreeze activity" RELATED []
synonym: "ice crystal binding" EXACT []
synonym: "ice nucleation activity" RELATED []
synonym: "ice nucleation inhibitor activity" RELATED []
is_a: GO:0005488 ! binding
intersection_of: GO:0036094 ! small molecule binding
Expand Down Expand Up @@ -466441,6 +466435,19 @@ property_value: term_tracker_item "https://github.com/geneontology/go-ontology/i
created_by: rynl
creation_date: 2024-09-27T05:19:27Z

[Term]
id: GO:0160219
name: cortical endoplasmic reticulum membrane
namespace: cellular_component
def: "The lipid bilayer surrounding the cortical endoplasmic reticulum." [PMID:32735772]
is_a: GO:0005789 ! endoplasmic reticulum membrane
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0032541 ! cortical endoplasmic reticulum
relationship: part_of GO:0032541 ! cortical endoplasmic reticulum
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29159" xsd:anyURI
created_by: rynl
creation_date: 2024-11-11T23:58:54Z

[Term]
id: GO:0170001
name: ergothioneine transmembrane transporter activity
Expand Down
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