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SaddlePoint Approximation implementation of GxE analysis

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SPAGE

SaddlePoint Approximation implementation of GxE analysis

How to install and load this package

library(devtools)  # author version: 2.0.1
install_github("WenjianBi/SPAGE")
library(SPAGE)
?SPAGE  # manual of GxE analyses in SPAGE package

Current version is 0.1.5. For older version and version update information, plesase refer to OldVersions/

Please do not hesitate to contact me ([email protected]) if you meet any problem. Suggestions or comments are also welcome.

Reference

Wenjian Bi, Zhangchen Zhao, Rounak Rey, Lars G. Fritsche, Bhramar Mukherjee, Seunggeun Lee, A Fast and Accurate Method for Genome-Wide Scale Phenome-Wide G×E Analysis and its Application to UK Biobank. American Journal of Human Genetics (2019), 105, 1182-1192.

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