DESCRIPTION

Package: SPAGE
Type: Package
Title: SaddlePoint Approximation implementation of GxE analysis
Version: 0.1.5
Published: 2019-08-20
Author: Wenjian Bi; Shawn (Seunggeun) Lee
Maintainer: Wenjian Bi <wenjianb@umich.edu>
Description: A scalable and accurate method, SPAGE (SaddlePoint Approximation implementation of GxE analysis), that is applicable for genome-wide scale phenome-wide GxE studies (PheWIS). SPAGE fits a genotype-independent logistic model only once across the whole-genome analysis to reduce computation cost and uses a saddlepoint approximation (SPA) to calibrate the test statistics for analysis of phenotypes with unbalanced case-control ratios.
License: GPL (>= 2)
Imports: SPAtest (>= 3.0.0)
Encoding: UTF-8
LazyData: true
RoxygenNote: 6.1.1