No such keg: /opt/homebrew/Cellar/r

pkg-config 0.29.2_3 is already installed and up-to-date. To reinstall 0.29.2_3, run: brew reinstall pkg-config

HOMEBREW_NO_INSTALLED_DEPENDENTS_CHECK is set: not checking for outdated dependents or dependents with broken linkage!

unable to access index for repository https://bioconductor.org/packages/3.18/bioc/bin/macosx/big-sur-arm64/contrib/4.4:

unable to access index for repository https://bioconductor.org/packages/3.18/data/annotation/bin/macosx/big-sur-arm64/contrib/4.4:

unable to access index for repository https://bioconductor.org/packages/3.18/data/experiment/bin/macosx/big-sur-arm64/contrib/4.4:

unable to access index for repository https://bioconductor.org/packages/3.18/workflows/bin/macosx/big-sur-arm64/contrib/4.4: