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Update README.md
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xiechengyong123 authored Apr 9, 2023
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Expand Up @@ -46,29 +46,3 @@ library(friendly2MR)

![1679155331649](https://github.com/xiechengyong123/friendly2MR/blob/main/%E5%BE%AE%E4%BF%A1%E5%9B%BE%E7%89%87_20230319000148.jpg)

## 更新日志:

1.添加了四个函数:分别是batch_ukbb_chrpos2rsID,clump_data_local,find_multiexposure_multioutcome_epigraphdb,gwasvcf2TwosampleMR_local;

batch_ukbb_chrpos2rsID:调用ukbb数据库的参考数据variants.tsv.gz对ukbb中的GWAS数据批量化进行SNP位点注释;

clump_data_local:调用ieugwasr包,在本地电脑进行去连锁不平衡,此功能可用于工具变量较多,在线进行clump时总是报错的情况;

find_multiexposure_multioutcome_epigraphdb:调用epigraphdb数据库的数据,对多个暴露和/或多个结局进行快速筛选;

gwasvcf2TwosampleMR_local:将从IEU官网下载到本地的gwasvcf文件转换为TwosampleMR的暴露或结局格式;

2.修改函数名称:原包中的find_anyexposur_outcome和find_exposur_anyoutcome函数名称进行更改:

find_anyexposur_outcome-->find_multiexposure_outcome;

find_exposur_anyoutcome-->find_exposure_multioutcome;

3.添加了函数和参数的注释,便于观众老爷们的理解。

4.文件中包含了ukbb的参考文件,太大了无法上传,只能存在我的百度云盘,链接:https://pan.baidu.com/s/1fdQu2rluE2fd6sgXcHIX0g
提取码:4sc4。

5.**该R包只分享10个人且30天内有效,先到先得,过时无效**

----------------------------------------------------------2023年-4月-9日-----------------------------------------------------

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