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iPhyloGeo++ is a bioinformatics pipeline specifically developed for phylogeographic analysis. This open-source, multi-platform application was created by the team of Professor Nadia Tahiri (University of Sherbrooke, Quebec, Canada) and is implemented in Python. This tool can be used to obtain trees from climatic data of the regions where the samples have been collected. Those climatic trees are then used for topological and evolutionary comparison against phylogenetic trees from multiple sequence alignments (MSA) using the Least Square (LS) metric and Robinson-Foulds (RF) distance. MSA that yield trees with significant LS and RF values are then optionally saved in folders with their respective tree. The output.csv file contains all the significant MSA information (see Worflow Section for more details).
iPhyloGeo++ offers the following features:
- Select a sequence Fasta file and climatic file in an accepted format (CSV)
- Run a global sequence alignment from the Fasta file
- Illustrate climatic data with location
- Compare and compute the evolutionary distances between genetic trees and climatic trees (e.g. RF distance and LS metric)
- Create and save consensus MSA
[in progress](in progress)
Please email us at: [email protected] for any question or feedback.
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