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Analysis of cyTOF data acquired from CD4+ T cells by tSNE

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Analysis of cyTOF data acquired from CD4+ T cells by tSNE

A sample workflow which can be applied to both standard flow cytomertic and CyTOF data. The analysis includes the following steps:

  1. Data import and preprocessing
  2. Transformation
  3. Producing diagnostic plots
  • MDS
  • NRS
  1. Cell population identification with FlowSOM and ConsensusClusterPlus
  2. Visual representation with tSNE/UMAP
  3. Cluster merging and annotation
  4. Differential analysis
  • Differential cell population abundance
  • Differential analysis of overall marker expression

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Analysis of cyTOF data acquired from CD4+ T cells by tSNE

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