Update README.md

rajewsky-lab · Apr 11, 2024 · 9c1bfd4 · 9c1bfd4
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 # Huntington_midbrain_organoids
-Code related to single cell transcriptomic analyses in the manuscript 'Mutant Huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure'
+Code related to single cell transcriptomic analyses in the manuscript 'Mutant Huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure'.
+
+You can run the notebook using the data files from the related GEO repository starting from the digital gene expression matrices generated by Cell Ranger or directly from the pre-processed Seurat objects (recommended). In the latter case, please ignore the code before the import of the pre-processed object with the readRDS function.