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@pirl-unc

Personalized Immunotherapy Research Lab @ UNC

Collective of researchers at UNC-CH who combine experimental and computational approaches to develop new immunotherapies and bring them into the clinic.
README.md

PIRL

The Personalilized Immunotherapy Research Lab (PIRL) is a multi-PI research group at the University of North Carolina - Chapel Hill. We work on identifying the determinants immune-mediated tumor clearance in a way that's fully personalized to each individual and their cancer. That high degree of personalization is manifested in algorithms for antigen identification across the spheres of genomics, proteomics, and machine learning for immunology.

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  1. mhcgnomes mhcgnomes Public

    Parsing MHC nomenclature in the wild

    Python 16 3

  2. ace ace Public

    Jupyter Notebook 2 1

  3. defense-against-the-dark-arts defense-against-the-dark-arts Public

    Course website and resources for BCB 731

    HTML

  4. golfy golfy Public

    Heuristic solver for pooled peptide experiment design

    Jupyter Notebook 1

  5. lens lens Public

    Landscape of Effective Neoantigens Software

  6. are-we-good are-we-good Public

    CI status of every project we develop and/or help maintain

Repositories

Showing 10 of 76 repositories
  • nexus Public
    pirl-unc/nexus’s past year of commit activity
    Nextflow 1 0 0 0 Updated Dec 20, 2024
  • tcr_translate Public Forked from dhuvik/tcr_translate

    Accompanying Repository to TCR-TRANSLATE paper.

    pirl-unc/tcr_translate’s past year of commit activity
    Python 1 1 0 0 Updated Dec 19, 2024
  • TCRpMHCdataset Public

    Python Class for Handling Many-to-Many Nature of TCR::pMHC Data

    pirl-unc/TCRpMHCdataset’s past year of commit activity
    Python 1 Apache-2.0 1 0 0 Updated Dec 15, 2024
  • NeoantigenProfiler Public
    pirl-unc/NeoantigenProfiler’s past year of commit activity
    R 0 0 0 0 Updated Dec 13, 2024
  • bbn963_fusion_transcript_pipeline Public

    A pipeline associated with the longread fusion pipeline used to extract fusions from our associated pacbio bbn963 data.

    pirl-unc/bbn963_fusion_transcript_pipeline’s past year of commit activity
    R 0 0 0 0 Updated Dec 13, 2024
  • nutm1-fusions Public

    Hunting for T-cell epitopes in recurrent NUTM1 somatic fusions

    pirl-unc/nutm1-fusions’s past year of commit activity
    Jupyter Notebook 0 Apache-2.0 0 0 0 Updated Dec 11, 2024
  • pirlygenes Public

    Gene sets used for cancer immunotherapy expression analysis

    pirl-unc/pirlygenes’s past year of commit activity
    Jupyter Notebook 0 Apache-2.0 0 0 0 Updated Nov 26, 2024
  • longread-fusion-transcript-pipeline Public
    pirl-unc/longread-fusion-transcript-pipeline’s past year of commit activity
    Shell 0 0 0 0 Updated Nov 15, 2024
  • lens Public

    Landscape of Effective Neoantigens Software

    pirl-unc/lens’s past year of commit activity
    0 0 0 0 Updated Nov 12, 2024
  • pdf-reports Public

    Helping code for compiling plots and other outputs into presentation pdfs.

    pirl-unc/pdf-reports’s past year of commit activity
    R 0 GPL-3.0 0 0 0 Updated Nov 4, 2024
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