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update changelog
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nvnieuwk committed Jan 15, 2024
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The format is based on [Keep a Changelog](https://keepachangelog.com/en/1.0.0/)
and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0.html).

## v1.4.1dev [date]
## v1.4.1 - Lively Leuven - [January 15 2024]

### New Features

1. Added the `--output_suffix` parameter to add a custom suffix to the basename of the output files.
2. Implemented files for the alphamissense plugin of VEP.
3. Added the `--only_pass` parameter to only output variants that have the `PASS` flag in the FILTER column. (This is only applied when `--filter` is also given)
4. Added the `--keep_alt_contigs` parameter. This will tell the pipeline to not filter out the alternate contigs, which will now be done by default.
5. Add dbsnp Ids to VCFs coming from vardict. This will be done automatically if a dbsnp VCF is given to the pipeline through the `--dbsnp` parameter.

### Improvements

1. Updated the seqplorer profile so that the output filenames are correct for easy import
2. Changed the separator in `--vcfanno_resources` to `;`
instead of `,` to allow commas in glob patterns.
3. Removed the reheader step from the vardict subworkflow and added a simple sed substitution to the vardictjava module
4. `vcf2db` now uses a python 2 environment to increase it's stability

## v1.4.0 - Kingly Kortrijk - [December 6 2023]

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