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Import and analyse large-scale biomedical knowledge graphs and ontologies. 🕸️⚙️💻⚙️🕸️

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KGExplorer


License: GPL-3
R build status

Authors: Brian Schilder, Hiranyamaya Dash

README updated: Dec-18-2024

KGExplorer: Biomedical Knowledge Network Construction and Analysis

Query, construct, and analyse large-scale biomedical knowledge graphs and ontologies.

If you use KGExplorer, please cite:

Kitty B. Murphy, Robert Gordon-Smith, Jai Chapman, Momoko Otani, Brian M. Schilder, Nathan G. Skene (2023) Identification of cell type-specific gene targets underlying thousands of rare diseases and subtraits. medRxiv, https://doi.org/10.1101/2023.02.13.23285820

Installation

if(!require("BiocManager")) install.packages("BiocManager")

BiocManager::install("neurogenomics/KGExplorer")
library(KGExplorer)

Documentation


Session Info

utils::sessionInfo()
## R version 4.4.2 (2024-10-31)
## Platform: aarch64-apple-darwin20
## Running under: macOS Sequoia 15.2
## 
## Matrix products: default
## BLAS:   /Library/Frameworks/R.framework/Versions/4.4-arm64/Resources/lib/libRblas.0.dylib 
## LAPACK: /Library/Frameworks/R.framework/Versions/4.4-arm64/Resources/lib/libRlapack.dylib;  LAPACK version 3.12.0
## 
## locale:
## [1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8
## 
## time zone: Europe/London
## tzcode source: internal
## 
## attached base packages:
## [1] stats     graphics  grDevices utils     datasets  methods   base     
## 
## loaded via a namespace (and not attached):
##  [1] gtable_0.3.6        jsonlite_1.8.9      renv_1.0.11        
##  [4] dplyr_1.1.4         compiler_4.4.2      BiocManager_1.30.25
##  [7] tidyselect_1.2.1    rvcheck_0.2.1       scales_1.3.0       
## [10] yaml_2.3.10         fastmap_1.2.0       here_1.0.1         
## [13] ggplot2_3.5.1       R6_2.5.1            generics_0.1.3     
## [16] knitr_1.49          yulab.utils_0.1.8   tibble_3.2.1       
## [19] desc_1.4.3          dlstats_0.1.7       rprojroot_2.0.4    
## [22] munsell_0.5.1       pillar_1.9.0        RColorBrewer_1.1-3 
## [25] rlang_1.1.4         utf8_1.2.4          badger_0.2.4       
## [28] xfun_0.49           fs_1.6.5            cli_3.6.3          
## [31] magrittr_2.0.3      rworkflows_1.0.3    digest_0.6.37      
## [34] grid_4.4.2          rstudioapi_0.17.1   lifecycle_1.0.4    
## [37] vctrs_0.6.5         evaluate_1.0.1      glue_1.8.0         
## [40] data.table_1.16.2   fansi_1.0.6         colorspace_2.1-1   
## [43] rmarkdown_2.29      tools_4.4.2         pkgconfig_2.0.3    
## [46] htmltools_0.5.8.1

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Import and analyse large-scale biomedical knowledge graphs and ontologies. 🕸️⚙️💻⚙️🕸️

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