Mohni2014

ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency.

• Mohni et al, ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency. Cancer Res. 2014;74:2835-2845

The custom siRNA library targets 240 known DNA replication and DNA repair genes with four unique siRNAs per gene in individual wells.