Simulation implementation and simulation results for the trial operating characteristics.
To build this site, you need to have a recent version of quarto install plus there is a dependency on the roadmap.data R package, see [https://github.com/maj-biostat/roadmap.data].
Simulations are configured via Makefile.
Run make list to see all targets.
At the time of writing make sim01 and make sim02 are the primary simulations.
The former runs a single analysis and summarises the power at different treatment effect sizes.
The range of effects are from log(1/2) to log(2) in all arms.
Rstudio: Version 2024.04.2+764 (2024.04.2+764)
cmdstanr::cmdstan_version() [1] "2.35.0"
To determine what version of quarto is being bundle with rstudio, open the terminal (inside rstudio) and type:
quarto check
As of the time of the last commit of this document, the version used is (all paths deleted):
Quarto 1.5.52
[✓] Checking versions of quarto binary dependencies...
Pandoc version 3.2.0: OK
Dart Sass version 1.70.0: OK
Deno version 1.41.0: OK
Typst version 0.11.0: OK
[✓] Checking versions of quarto dependencies......OK
[✓] Checking Quarto installation......OK
Version: 1.5.52
Path: -
[✓] Checking tools....................OK
TinyTeX: v2024.03
Chromium: (not installed)
[✓] Checking LaTeX....................OK
Using: TinyTex
Path: -
Version: 2024
[✓] Checking basic markdown render....OK
[✓] Checking Python 3 installation....OK
Version: 3.10.1
Path: -
Jupyter: (None)
Jupyter is not available in this Python installation.
Install with python3 -m pip install jupyter
[✓] Checking R installation...........OK
Version: 4.4.1
Path: -
LibPaths:
- -
knitr: 1.47
rmarkdown: 2.27
[✓] Checking Knitr engine render......OK
In theory, this should pick up whatever is on your system. I think polyfill.io affected versions of quarto < 1.5 so you should probably update if you are not on the latest.