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# Description: | ||
# Author: Haley Hunter-Zinck | ||
# Date: | ||
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# setup ---------------------------- | ||
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tic = as.double(Sys.time()) | ||
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library(glue) | ||
library(dplyr) | ||
library(synapser) | ||
synLogin() | ||
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# synapse | ||
synid_file_dd <- "syn25468849" | ||
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# parmaeters | ||
drug_name <- "Irinotecan" | ||
oth_drug_names <- c("Fluorouracil", "Irinotecan Hydrochloride", "Leucovorin Calcium") | ||
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# functions ---------------------------- | ||
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#' Download and load data stored in csv or other delimited format on Synapse | ||
#' into an R data frame. | ||
#' | ||
#' @param synapse_id Synapse ID | ||
#' @version Version of the Synapse entity to download. NA will load current | ||
#' version | ||
#' @param set Delimiter for file | ||
#' @param na.strings Vector of strings to be read in as NA values | ||
#' @param header TRUE if the file contains a header row; FALSE otherwise. | ||
#' @param check_names TRUE if column names should be modified for compatibility | ||
#' with R upon reading; FALSE otherwise. | ||
#' @return data frame | ||
get_synapse_entity_data_in_csv <- function(synapse_id, | ||
version = NA, | ||
sep = ",", | ||
na.strings = c("NA"), | ||
header = T, | ||
check_names = F) { | ||
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if (is.na(version)) { | ||
entity <- synGet(synapse_id) | ||
} else { | ||
entity <- synGet(synapse_id, version = version) | ||
} | ||
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data <- read.csv(entity$path, stringsAsFactors = F, | ||
na.strings = na.strings, sep = sep, check.names = check_names, | ||
header = header) | ||
return(data) | ||
} | ||
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# read ---------------------------- | ||
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dd <- get_synapse_entity_data_in_csv(synid_file_dd) | ||
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# specific drug ---------------------------- | ||
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drugs_str <- unlist(dd %>% | ||
filter(`Variable / Field Name` == "drugs_drug_1") %>% | ||
select(`Choices, Calculations, OR Slider Labels`)) | ||
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drugs <- strsplit(x = strsplit(x = drugs_str, split = "\\|")[[1]], split = ", ") | ||
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res <- unlist(lapply(drugs, | ||
function(x, pattern) {return(grepl(pattern = pattern, x = x[2]))}, | ||
pattern = drug_name)) | ||
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print(drugs[which(res)]) | ||
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# find codes for drugs ---------------------- | ||
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for (oth_drug in oth_drug_names) { | ||
res <- unlist(lapply(drugs, | ||
function(x, pattern) {return(grepl(pattern = pattern, x = x[2]))}, | ||
pattern = oth_drug)) | ||
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print(glue("{oth_drug}: {drugs[which(res)][[1]][1]}")) | ||
} | ||
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# close out ---------------------------- | ||
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toc = as.double(Sys.time()) | ||
print(glue("Runtime: {round(toc - tic)} s")) |