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Support zero depth sites #48

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Support zero depth sites #48

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y9c
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@y9c y9c commented Sep 6, 2021

For analyzing multiple samples together, it is useful to accept sites whose depth is 0 within some samples.

@Sfeng666
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For analyzing multiple samples together, it is useful to accept sites whose depth is 0 within some samples.

I agree.

It also make more sense to allow coverage = 0. Both the mapping quality (-m) and base call quality (-q) filterings allow no filtering (threshold = 0).

@piechottam
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I will try to incorporate -m and -q with threshold 0.
A coverage of 0 requires extensive updates to how the test-statistic is calculated - I'll check this.

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3 participants