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hbp-bsp-syn-plast

LTP and LTD syn mod files

This repository contains two mod files: "ltpltd.mod" and "STDPE2Syn2.mod".

These mod files are typical examples of biophysical models of synaptic plasticity; they will be integrated in hippocampus microcircuits.

Reference papers are:

  • Bianchi et al. 2014, Effects of increasing CREB-dependent transcription on the storage and recall processes in a hippocampal CA1 microcircuit. Hippocampus. 2014 Feb;24(2):165-77. DOI: 10.1002/hipo.22212
  • Migliore et al. 2015, Effect of the initial synaptic state on the probability to induce long-term potentiation and depression.Biophys J. 2015 Mar 10;108(5):1038-46. doi: 10.1016/j.bpj.2014.12.048.

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