Simulated medium model #15
Merged
Conversation
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
…works for both steady state and INST simulations
The dataset simulates the frutose experiment. This simulation works, however the flux distribution is now very accurately determined from the simulated data, i.e. large uncertainties.
To further improve in information gain from the simulated data we setup two parallel experiments utilising both labelled glycerol and fructose. This narrowed the uncertainty of the flux estimates. The validation notebook was added to examples page in the documentation.
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment
Add this suggestion to a batch that can be applied as a single commit.
This suggestion is invalid because no changes were made to the code.
Suggestions cannot be applied while the pull request is closed.
Suggestions cannot be applied while viewing a subset of changes.
Only one suggestion per line can be applied in a batch.
Add this suggestion to a batch that can be applied as a single commit.
Applying suggestions on deleted lines is not supported.
You must change the existing code in this line in order to create a valid suggestion.
Outdated suggestions cannot be applied.
This suggestion has been applied or marked resolved.
Suggestions cannot be applied from pending reviews.
Suggestions cannot be applied on multi-line comments.
Suggestions cannot be applied while the pull request is queued to merge.
Suggestion cannot be applied right now. Please check back later.
To improve the confidence in the INCAWrapper we implemented an extra validation scenario utilising a medium-sized (59 reactions) model from the literature. In the scenario, we simulate two parallel labelling experiments and use the simulated data to estimate the true fluxes.