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a/2023/data/popgen/reference.fa b/2023/data/popgen/reference.fa new file mode 100644 index 00000000..1cc282d7 --- /dev/null +++ b/2023/data/popgen/reference.fa @@ -0,0 +1,4 @@ +>scaffold_1 +AATTTATCTTTTACACATGATATAGTCTAATTCAATAAATAAAGAATTATGTTTTGTTCTTTTTTAAATACTTTTACTCTTTAATTAGTCAATAAATACTTAATTTTTtAATTAATTAGAAATAAACGTATTAAGATCAAATTATATTAATCAATATTAATTTAATTTATATTATTAGAATATATGATACATGTTTGTTGTCACAGTATCTTTCAGTTTGGTATCTTATATAGGTATATTAAGAAAAGTTCAAATCCCTGTGTGAATGTCACTGTATATTTAACAAAATATGAAAGATAGGTTTGCTTTTACTAGTTGTTTTTGTTGTCAAGATGTTTTATGGATCACATTTCTCGAATATACTGTTCAAAACAGAAGTGTCTTCTTCTTGATTCTTTCCACAAATATTTGTAGTTCAAAAAATATATGATTTTGCGTAATTGGAATAAACTATAATTACCACAGATTATAATTGGAAAAATTGTTTTATGTGTCCGCGAAATGATGAGAGATAGTATCACACAATGGGGTGTGAAGCGAGCAAACTCCACAGGATAAAAAAAAAaTTACTAGCGTGCAGAGAGAAGGGTGGCAATTTATCTTCACGTCGGAAATTGTGCAAATATGACTCGCGTATCAGGAAGGAATATTAAATGAGCGTCAGATTGAAGACGGAAAACGCAGTATGTCATGTTACATTAAAATGTGGATTTATTTGAACAATTGAAAAGATATAACTTTTTTtGCAAAAATTTATTCTTTTATTCAATTAATAAAGAGCTTTAATTACATTTAAATAATTTTAAATAAAGATTAAAATCATTATATTAAATTATTATATAAACAACATGTAACGTCCATAACGTTTATTTTTTtGTAAAAATAAATTTGTtATTTTtAAAaGCATTATTTTCTCTTTAAAAATAAATACATGTCAATCGTGAAATTGATTCTTGTGATTATTAAGCAATTTTGTATAAAATATTTTATGTCGACTGTAACAAACAAACGTATGTCATTCTGTTTACATTATTTTCCGTATTCTATTTCCATATTTAACGATAAACATTAATTGTTATTATTTTATCCGATTTGTAAATTCTTTAATTGTACATATGTATTAGAATTATTAGATAAAACGAATCGGTTCAACCAAAAGTAGAAAATGTTTTTGATTTTACTTCGTGTTTTAAGCGAAGGAAAATATTTATAACATTACAATAAATAGCCGAAGGCATTCAAATTATGAAGTGATATTTTTGCAATTAAATAGTGTATAAAGTTAAAATAAAATAGTAAATTATTCAGTTAGTTTATTAAGCTGAATTTTCTTAAATAATAATAACGTTAATATTTAGCTACTAATATTTTAAAATAATATTAGATGTAAATAGCTGTATAATTCAATAATAATAACGCCCATGCAATCAAATTAAATCATATAATTCGGAAAACATAGCTTTATATAACAAAAGTATATCAATATTATTAAAATGTTTGCTACAAAATAAATTAAAATTAATAATATAATAAAATAATGATTAAAAATATCACAAAATATTATTTATAAAACATATAGGTATGTGTTATATTGCACAGGTATTCATTGCTATGCATGGTATGTTTAGGAAGAAAATTTGAATGAGAATTTGTGTATCAGATGTGTTAGGTGCAAGTTCAGGAAATTGCTCCGAATTATTCAAGGAATCTCAGTACATAAAGCCCCAGATCTGTTACCACTCTCTGTAGAGGCTGGAACGgTCCGCATCTCCTTTTGTGCAGTTATGCAGGCGATGATCCTCCGCATCGTGCATCTACGCGAGCCTGGCAGTTAACTGCCATTCATTTGCAGCCTGCCATGCGTCAATCATACGATGATCAGACTTCAATACTCGCACACTACTTCGTATGTGGTACTGTCGGTAGAATATGCGTCCCAGCAGTGCGCGTATGCGAGAATATGCGTCGAGTTAGTACCCGGCGATGATGGTACCAGAAATATATAGATCACGTTTCTGACATTTCATGCGCTCGTCAGTATTCAGGTTCCATTTACCGTATCTGATCCGGCTTATCGACTTATAAGCGAATATATACATAACCATTATTTATGATTCACGCATGTATGTGTCTTCAAACATTTAGTATAATTTTAACGCACATTTCGCAATATTTCTCAACAAATCATTATAATATCTTTAAATTATTGAATTAAATTATTTATTGCGCACGCACATTACTATTAGTATTATTACTTGTAATTTATACAATTCACAATTTGAGTTTTCACCATCTAAATATGTGATCGGATTTTTCAAAAATTTTAATGCTGAGAAATTGTGTATGTGGGTAGCTTTATTTGATTGAAAATACTGCAACTTTCCTAGAGAGAAAAAGTTTTCTCATACTGCTCCACCCACAGATGTTAATCAACCAGAGTGAATTGAACTTTATATTTTATATAAGAACTTTTACAAAAAAAGCTGCGTAGCTTTATTGGTTCTGTGTGTTTTAAATATAATGCATTTAATCAAGCTAAAACCGAACAAAAAGAGGGTGCAACTTTCATTATAAGTGAACGCAATTTTAATTAAGACCGCAGGTTAAATAACGGAGACGGAATATTGGATATCTTATTTGTAAATATTTGAAATATATAATCTTTATTTCTGCTAAGCTGAATGTGCCGCATTTTAATGTAGAATCCAAAATTAATGTACGTTTTTTTtATAAAACTAGAACGACCGTAGTAGTATTGTAATGTGGCAATATTTCTGTAGATATAACAAAGCTTTCCACTCTATCTAAATTTTTtATATCAAAGCCTGAAAGTTAATTTTTTTtACGTACGCGCATATATGTTAAAACAGCATTGGTCGACCTTTGCGATATTTATCCGATATTGCACAAAGCTGGTTTTCAGTTTCTTTTATCACATTTGTACTGTGCACATATATTTGCATGATATATTTTTTTTCATTTAATATTTTATTTCTATTTTTCAAACAATTTTGCTAAATTTGATAAATTTAAATATGTGTTTTATATTGAATGTATTTTACTCATGCGACATTTTTAATTAAAAATTTTAATTACAAATAAAAAATAATCTGTGATAATACCAAATAAATATCACGAAATACAATGCAATCAACAATAATTGTTTTATAAATAAAAAACCATAAAGAATATATTACATGCTAATATATGTAATCCATGTAAATTTGCTAGTGTATGAAAGTGCACTTATTTGGAATTGTAATTATTACCATACTATAAATTCCGTACATATTTTCGATTAGATCTGAAAAGCCGACGTCTCCTTTATGAAGAAATATCGATTTCTCACTTCATTGCAACAGAAAATTCTCCATCACGTTCTCTCTTTCTAGCGGCATACCACCGATCATCTTATAATAAATGCATGTATGCAGAATACAGGCACGACATACTATCACTTCACCTACTGCCCCATTTTCGACAGTTTTGCATCGATTTATTTGACCTTATAATAACATGTCAGTGTGCACCGCATTTTTGTATTAAACATTTCATATTTATGTCTAACATAAATATTACAAGACATTTTAAAGTAAATTCTCATTTATAGATTAAAAAaTATTTTTTtAAAGTTTTAAATAATTTAAAAAAaGTTAATAATAGTAAATTAAAATAAAAACCGTAAATACTTAATAAAAATTACTTTATATTATGCATACATTAGCCTTTAAAGATATCGTGCGATTTTGTCATTTTATTTTCACGATATTCCAAAATTATTTTGGCAGAGAAAGATTCGAGAGATAATTTTAAACAACTCCACATATTCTTGATCTGATAAATATACGAACAAACGACTATTATCTTTTGTTCTTTTCACAAGAATGTATGGAATACGTTAGTAAAACTTATTGGCAATTTTCCCTACTATCTATAAGTCTGTCGCTTTCTTACATATATATACACGTGTATATTGCTTATCCATACGTACATGCGATATGCAGAAGCGACGAACGATTCAGCAATGCTGTGTGACCTCGTTAGTGACTATACTTCCGCGGTATTTCCGTGGTATTTCCTTGGTATTTGATATCTATGTTCTAAGCAGTTACCTTTCTGTAGTATCTACCAACATCCGGCGGCATATGTAAATGCGTTTTGCAACGTATGTCCAATTACGTCCGTGATGAACGCTACCCTTAACGACTGTAAAGCTGGGGATGCCAGCCACTCGACACTTATACGCTTGGGGGATTATGCTGGCCATGAAATTATTCCCATTGCTGGTATACTAAGTAGGCATATACTGTATCATATCGTACTACGCGGACCATTTGGCACGATTTTCATCCCTGAATTCTAAGAACATCGTCAAACTAGACACAAATAAACAGTAAAAATTGGTTATATTATAGATTGAAAATTATTTTGTCTGTATTTCAAACCTTTTTAGTTTTTATAAAAATTAATTATTTTTACTTCAACTTGGAAGGTTATAGTTTTTATATTAAGCATATATTTTAGATTTTTAACAATATTAGTTTTTATATTATAAGATACGTAACGTTTATTATTATATGTACACATAGAATAACAATATTCTACATGGAAAGAACAATTACAGCATTTTAAAATTTCGCTATATACAAATCAGAAAaTAATTTTATGACATAATGTGCCATTAAAATAATTATGTGGGACGCTCAAGCATGATAATGTTGCTGTATACAGTTTTGACATTGTATTCTATAGAGTTTTTTCAATGGTTCAATATAATTATTTTCATATTTATAATGTTTCAGCAAAATTGTTTCTTCTGTGTATAAATAATTCTGTGAAGAGCGTAATTATTTTGTATATTACACGTGTTACTGCATTCTGTATTCTTTGTACAATCAGATATTTATGACGTTATTATTCTAGATGCTATCGTAAAATTATAGGACGTTGCTAAAGCAAAGAATACAAGAGAAAATATTAAAGCGGTTATTAAATATTTAGCTAAATGCAAAAAGTTTCAAAAATTTATCTATCTTGCGAGCATTATTTCTTTAGTGCATAATCCACGATTTGACAATTATAACTAAAGCGAGAAGATAGTTATAATTGTCAAATCACGGAAGATATAATTTTACCGGAATACAGGAGATTAGGCTGCCACCTTAAATGGTGCTTAGGCAGATTATATATTCATAGCCCACACGAGAATGTGTTACTTAACTGTGGAGCTTCCCCAATATTCAAGAGTGACATTGCACCTGCCTCCGTTTCATACGTATATGTTTGATTCTCTAAGCTTTCTGTCAAAATTACATATTTTCTGTACTATACGTGCAAATAGGACAAGTTTTACAATCGTATTATATTATTGGAACATATTAATTATTTATTATTGGTATATATAATATTTATATGTATCTTGTATTATTTATATATAATATTAATATATTATGCAAACAGTTAATAATTTTACTGTAATAAAAAAGCTATTCTAAAACATTGGATGAAATGCCAATATGTCTATAAATTAAATATTGGAATGTACGTTATCATGTTTCCATTTGCGTCAAATATCAAGGGAATATAGGTTGCATGTTTGCACATAGCAATTTTGAAATATTGAAATTTCTCTCTCCAAATCGCGAAAGTCTTTATAAGTAATCATGTGCTTCAGATTTCAAGTATTACTACATAAATTATGTTAAACATTAAAATAATGTATAGACTTTTAAGGAAATTTATTTAAAAAATCAATGTTTTTATTTGATTATCTTCGTTCTACTATATTAATTATCTTAATTTATCATGTGTCTTATCAATTATTGTCACCATATATGTGTATTGTATATTAAGCGATTTAATAGCGTCTTAATTTAAATAAACATTAAGAAAGTTAATATTTATACTATTTTTATAAATTTTTTTCTCTACAAAAGATGAAAGACTTATCATGTTTGAATATGCGTTAACAATCTTTTGTATAGAATGAATTTATATCTTTACAGGATGTTACACATCCTTTCTCGTAAAACAATTACTTCCTAGTTGTAGAGATAACGATATAGTAAAGATAATGACATAATAGTTAAGCAGAGTTGATTCAACATGTAGAACAGTATATGTTGGACTATAGACGAAAGCTAAACATACAGTCACAGTACTAATCAGTACTATTGATAATTATTATTAATGCAGGTAATTCAATTTTACCATTAATTAGTTTTATTGGCTTATGCTTATCACATTATCACTATACTGTCGTTTTGCACGTTATCTCCGCTTGCACTCTTCTCATGTTAATTTATGTGTGGGTATTATTATATTGCATTTCATTTCATAATGCGTTTTACAATATGGCTCTAAATATTAATAAGTAGCACTTTATTGTGGAATTTATTGGTAGTAACGGCTCAGTGGATTCAATAATATTATCGAAAACGTTCGGTTCTGTGTCGATAAAATTTTCTCGCGCGTGAAATGAATAATATGAATTGCACATGCAAAATTTATTAAATGGATTAAAGGAACATTTTGAGCAGTTATGACTTTTCAGTCGGAAACTAATAACTATCTAACTAATATCCGGTTTGCTGCCGGCACTGAGGAAGTAGAATCATTTAACGAGAAATATTCGTTTAGGATTAATCTCCGTGCCCCGCCTCCTACCTTGTGGAAAAATTACGTAGTGAGAATTGCGAACTTTAAAAGCCCCAGTGAGATAATTCTCCTGGTACTTAAAGAATGGCCCAAGAGTTATCTCTGCTGACTTATAACTCTTTTTAAGTGTATGATCCGCGTTATAAAAATTTAAAGCTTTGTATTGCAAAGTATAAAATTACGTATAAATATTAAAATTTGCATTTTTTTTTAAAAATCGATAAAGTGTGAATAAAATTTTTGTCTAATATACTAACCATAATGTCTATTGACACACACTACCTTTGCATTGCGGTCACAGCTGCGGTCAAAGTTACGTTATCTATGGTCCGATTTGCGGCGAAACAAAGTGCAGCGGTATCAGTTGTATGTGCTTTCAACGAGTTTCGTTCTCTACGATATCGGAACGACCGAAGCATCGTGTGTAAAGTTTATAAATGATAGTACGAGAAATGTCAAAGCCGATTAGAGCATTTGGCTTTTATGGTGTAACTTTCCGAGTAACACGAATGCAATAAATATATGTTATTTTTTtGCTTTTTTACGTTCCGTAGTACATGTACAAAACAATGTTACATGTCTTTCCTAATTTTTTAACATAATATAATGTAAAGATTTATTATTATTGTTATTAATTAGGAGAGAAAAATATTGATATCCCAATCAGCAGACAATGTTTTTtAAATGTTTTTTtAAATATTTATTTTTCATTATAACGTTTTTtAAATATTTAAAAAaCATTTAAATATAAAAAAAaCATATTTAAATATTTAAAAAaCATTTAAAAAaTATTGTTTtCTGATTGGAAGTTAACATGATATTACAGCTATATATTTTCTAAATATTGATATGTCTAATTTAAATGTGTTTTGTTTTTAAAAAAACCAGTAGTCTCTTTATATGTAGAATTGAATACATTGAAATACTACTTTAATTTTAATAGATTTTTAATTCTATACTTATTATTTTTAATATTGCTGAAGAGTAACACCAATCACAGTCACTTCTAAAGATACCGCTAATGCGTTGAGAAGCACGTCTTTTCATCACACGTTTCAAATTAGCTGAGTAGTATATAGATTTACTGTAAAGGTAACTCGCGTACGTGGGATGACGACGGGCTTGAAATTCTCCAAGTTGAAATAGATTATCGGAGGTTCGGAGTTCATGCTGAGAGCTtGTCTCGTAGTTTGGGGTGTCGGAATCTAGCCCTATGTTATCTTAAGTCACAGCGAGATCTTATCAAATCTGATTACATTTACATACGTCTAAAACTGATCTCGGATGTGAGTTAACTTTGCACAACGGAAACAGCGCATGAAATTCCACAAGACAGCGTACATAGATGAGACATTAAGGTCCGTATTCAAAATGCGCTGATAAAATCTTAGCGCGTCTTTTGTCAAATAGAATGAAAACCTTGTTTTAAATATAATAATACAACGAAAACACGCACTAATATGTTTAATAGTTTTTAATAGGAGCTAAATATTTCAATGCTTTAATAACACAAATTGTTTCATGTATTATATAAAGTATAATCATCGTCGTTAAGAAAAATATTCGTATTTTTtAtCTTATTtATCTTATTTCAATATATCATTATTAGGGAAAATGTTATATTTTTTCtCATCTCATATATATATATATATATATATATATATATATATGTgtGtGTaTAcTATAtGtAtaTAcAGtANNNNNNNNNNNNNNNNNNNNtAtATATATATATATATATATATATATATATATATATATATGTGTGTGTAtACTTaTAATGATATACAGTAGCAAAATAATGTGTGTATGTACGTGTGCAATTATCAACAACTCAGTGTAATTAGAAAATGTTTATTTTTCTACTGTATGTTATTCTTCTATTTTAGCCTACCTAAAACTTGGCTTCCTTCAGCATCGCAAAGATATCTCACTCTTTGCTGCATATTGAAAATATACCAGGACATACCTTGTAGCGACAGTGGTGAAGCATGACATTTTGGAGAAGAGTTATGTCATAATACTAAATTTTATAGTAGCGTGTCTTCAAAGTAGAAAATTACATCTTATATAAACAGTCTGTAAACCGTTTATTCATATTTCTTTGTCTTTTAAATAAACGGTTACAAGCATGCTACATTTTTAATATTTAATCAAGTTGTTTTATTTTATAAATGCAACCTATTAAGAAAAAACTAGACTTTTTTGTAAAATGCTTTTACTTAAATAACAATTGAACTCCTATTTAAAGATAACCTAATTTACATTATAAATTAATCATAAATATATAATTAGTTGTTATTTTTTGTTATAATTTTAAAAGTTGAAGCATATAAATGTTACATTAAAACCTTGAAATGCACAGTTGATTGTAAAATAAAAATTATTCTTATATTACGTACGTCTTTGTCTACAATTTGAGACGGAATTATTGTTGTGCGTTAAATTTGCTTATACCAAGAAATCCAATAAATCCTAATGATCTCAAAGGGCAGCTACAGACGATTATTACTTGGCGGTACAATACTTGTACTTACTACCATGCTTTCGCCAATTTTCTCAAAACAAAGAGTCTTGATTGAAGAGAGCCCTTCAGACCTGCACATTTGCGGGAAATTCGTTATAGTCGAGTTTGATTTCACGTTGCAGCTCCAATCGTTAAAGCACGCGCACAATGCAGCTACCATTTTTGTTGTTAACGCTACCCGATGGTATCGAAATTCTAAAGATAAAAACAGAATTATATTCAGGAATGTTGTTCGCGCATATGTCTGTAAAACTTCACACGACGTTGTATGCTATTGGTTTTTGTTAAAGGATCAATATAACAAATATTTGTTAGCAATTTAACATCGTGCAATTGATTTGAATTGATAAATAATACAGCAATTGTTATAGTATTATAGCATAAAATAGATGGCTGCATGCTTGCTTTCAGCGTTTTCATTTTACGATGAGAACGATAATTTTTTACAGATACAATATAATCATAAATGTACTCACTGTAAAAGTAATTAAAGTGCAAAGGTTTTCTGCTTTGAGATAATGTCAAAGAGAAACTTTACATCATTTATTACATTTATCCATTTTAACTCAAAAATTGAGATAGATGTAATTTCGATGGATATTTAGATACTCTTGTATTTATTtATTtCGATTTATGTAAAAGTTCAGATGGATATAGTTTCAATAGCTGTTTATTGTTGTCATTGAAATGATATTTCCTTGAATATTTACTTTTATTGACAGCAAGGACTTTTATTGATAGCAAATCGATCTGGTGGTTTCAAAATACGTTTTGTCATATCTAGAACATGGAAAATATTGAAACTATCGTTTTCGATTTCTATTTCAAACTGTACGCTACTCTATCTCTGCTTTATTTGGTAGTCCGACTGTTATTCAAAGAATTTCCTATCTGTTTGTTTGTACATCTAGTGTCGAAAATTTCGTATTTTTTTAAACAGTTATAGATAAATAACTATTAAAGAAAAATATCCATAATATTTTAATCTCTAAAGTTTTTACATATTTTATTATTACAAATATATTAATTTAAATTTATAATATTTTTCTTTGAATTTCAAAATTTTTAGATGATTACATTTTGAATATATTTAACTGGGAAATAAAAAAAAAaCGGAAGTATCTTTTACACGATTTTTAATACTATTAACTTAATATTACAAAATTGGATTAAAAAATTATTTTGAATTACAATAAAAAAATTTTGAAAAAAATTTGTTATTCCGTTTTGTGTTTTTTCAAATTATGCTTATATTTTGAATATAATTATTTTGTACATATGTGCGTAGGCATAACAGATGTGGTTATGACGAAATCGATTACAGTGACTCATATCTAAAAAGAGATCAAACACCAGAACAGATTGTGCTGAAACAATTACTGATCTTTATCTCTTTCTATTTAAAACTGACATTTTAAATCATTTATACATTCATAAAATTATATGTTTAGAATTAGCATATAAGTTATAAAAAATCAATATTGTTAAATATTTTTATATTTACAAATTTTtAAAACTATTAAAAAaTTACACGCATATTCAAGATAACAATAAAAGATAAAAATCTTCAATGATTGCTGCTTAAATCAGAGAAAGAGAAAGAGAGAGAGAGAGAGAGAGAGAGAGAATAATAAGTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAgAAGAAGAAGAAGAGAGAGAgAGAGAGAGAGAGAGAATAATGTAAAAAAAAAAGAAAATTACTTGCTGATTTAATAATAAATATTTAAATAAAACTAATATGTTCATAATCAAAATACCATTAGTTAGTAACATTACATATTtACGTTTATAAATACAGGAAATTATTCACGATGGAGGTATTCAATATAAAGGTTATAAACAGTATTTTTGTTtATTTTtATtAAAAAaTATATTCCTATATATTTTTTtAATAAGTAAAATTCTTAGAAAATCCTATTTGCACTGAAATCATTGTAGCAAAAACTTCAGAGAAAATTTTTTCTCTGTATTTTATTTGAGTCTTATTGAGCAAAAAGTTGCGGAGAAATCTTTCAAGTTTTAGTTAAATTTACTTTTTTCGTCAGATGATACGAAAAAACATTTTTACACATTTTTAACATTACTTTTTTATATTTATGATTATTCATTTATATTACACGTATAAAAGACGTTTTTATAATATATCTGTGGATTATGTTTGGTCAATTTCTTACGGCTTACTGTACCCACTGTAGCTGGACCATTATGTATATTTGTGAAAGTTTTATTTGTACCTACGGTCCGGCAATTTGTGGACACCTATTTGTTTTCGTTGCCACGCTACTTCTCTCTTTTCACTGCGCATTTTTGCGTTATCCGTGTGTAAGCTACTAGAACAAAACCTGACAGTGTCCCATTCGGACGATTTGAGTGCAAACAATCGATTAATTAAAACCATTTGGAATTATTCTGTTTGTAATTAATGCGGTGTACGTTTTAACCGAAACAATAACTATCAAATATCTTTTTTGAATAAGCGAATGAATTAATAGAATTAAAATAGTAATGATTTCAGTCATTTATATATCTATATGCATATTTTTGAAAAAAAGTGAAGAAATGAAATGTATCTGTGATACTCAGATCAATTCCTTTTTATTAAAAGGAAAAAATTTGCCCGCTTGCAACATATTGGAATATTAAAGTCCGTATCCTGCGAAAGGTACAAAAAAAAaTTTTTTAATATATTTGTAATGTTTGTAATGTTTTATTAAAAAAAAaTACACGCACTAATTGAGAATAGGAAGATTTATTAAATAAAAGATTTAATTGTGATTTTATTTATATAACATAATATTTTTTTAAGCCAATTTCTATTTTTTTAAATATACTCTTATACTGTATTATTATTGTATTGTGTGATTTTATTAGCTATTATTGTGTTTAATATTTTATTAAAATAGTAAAATAAAGCTATATTACAAACAAATCTAAGAGAGAAATTAGCTTGTAACAAAATAAAAAGTAATAATAATTAAAAGAAATAAATGTTATTTTGAATCTTTATTTTTTTtATGTAAACCATTTATTTTGTCTTAGCATAACGCATAACTTAAATTCGCGAATATTTTGTTACTCAAAATAACAGGACCGACCCAGATTATCTCGCTACAATCTGTTCTATTTCATCTTGCAGAATCGATATCGATCGCGCGTGATCTCGTTGGTTCATTCGTCTTATCTAACTTTTGTATCTCACGGTAGTATCCGCCCAGTTTTTATACATTATAAACTATTCTCTCACGTTACTGGAGATTATTTATGGCTGATCGGAAATCTACATTACAAGTGGGAGTACCTTTATCAAATGTTTATCGATCGACCCACTACCGTTTAAACTGTTTTCTCGACGCAAACATGCCTTAATTCTCACACAGATACAGTTGCTCACAGATACGCTTGTCCCATGGGATAATGTGAGCGCTGATTTTCACGAAGCCGTTAAAAAGAACTCAATACCATTCCTGTGTGAGAGTCACTTTTTGTATAAAAGTCGAGTTACGTGTGTGGAACGCTTGGATAAGTGTTCCACACACGTGCTTGGATAAGATACAGTGATATCAAAAGTTTACGTGATATGAAAACGTATATATCATTTGAGATTAATTAAAAGTTGCCTTATAGATGATTTAAACTCATTGCAACTAATGGCACAGTCGTGTATAAAATTTTTATTTtACGATATTATAATAAGAATTCTTTTACATTCATAAAAATGAGGAATATAAAAAAAAaTAAATAGTTACAAAAAAaTTTTTATTTTTTtGTAATAAAAGGATATGAATGCAACATGTTCCTTTCTAATGTTATATCTTTTTAAATTAATTTATAAGTTTTATAAAACTAGAGAGACTTTATCATCGTCGTTTGACACTTTCGCAAGAAAAAAGAAACAGATATGGTTTTAAGAAAGCATCTTTATGCATACTTTTTGTAATTTTGTAAGAATGCCTGATAATTAAAAATATCAAGGGCTTCTAAAAAAAAAaGGAAAACTTGTACTGAGAAGATTAGTTAAGATTTACAATGTTAATAGAAAGGAAAATTACAGTCAATGAGACGACACCTTATAATCGGGCACTATGTTGCTGATAGTTATTAGAATTAAGTACGTGCTCGGAATTCTGCTCTCTTTAAACTGCCTCTCAGTTCAGGTTGCCATTACTTAGTCGCGCTGTGAAAGCGGAAACAATGCCATAATTCACTTAATTCGGCGAGCCGGAGGAAAATCCATTTGCTGCTGGAATCGATAATGGACCGGTGTGGTTGATTATAAAAAGTCACCACGCAAGTTAGGGGAATCGGATAAAAATGATAAAATTATTGCGGCAAATGAAATTTATCTTTAATTTTCTGAAGTACTCTTAATTAGTGCAGCAATATTGTGTATTATACGCTTTGTCATGTCTAATTCTATGTATAACTTTGTTCTTTACATTCGAGAACAAATATCTTAATTCTTTATTGGTATTGTTATAAATAAATCATTAAACGTCTTATCTTACTTTAATACTATTTGATACAATCAATAAAATACTTTATTTTTGGCGACTTTAAAATATTTATTTTGACGATGACAATGCCAATTCGAACAAGAGATTCCACTTGACGCTCGTGTCTTCTTGCGTACTTCAGAATAACTTCTTTTTATAGTGGCACTCAATCTCTCCTGCTCTGTCTTATTTCCATAGTCTGTTTGACTTTTCTCATCCAATTTTAGCAAACTCCCGAGCGTTTGCCTTTTTCCAATGTGATCCATTTCCATATTTCGCAGAAAATCGTCGGCGTTGGGCCATTTTGCCCACATATTCGCGTGACCGTAGAAAGTTTTAAAAGTTCCGATCACTTTTATCTATATTCATATTTCCACTTGCACATGCTGTGATTTTTAATCAATTTCAAATtCAATTCATATGCACCTCATCGTTCGTAGGATTCGCACCTCAATTTGATATGTCCTACAAACGTTATGCATATTCTCCACTTTTTAATGCAAATAAAAAAaTCTAGGCATTCGTATCTTTGTATTTGATTGGCTTATTCGCATGTCATAAAAAAAAaAaTATATATATATATATATATACACATGAGAAAaTTAAATCTAATAATAAGTATTTGAAATTTTTTTTtAGAATTTGATCTGTCAAATCATAGGATATAGCTGAGTGTGGTATTGTTGGGTGTGATGGTACTTGGATATGAGAACGTAGTGGTTTtATATATCTCTTTACGTTATATGTATTTACAAGTATTATTAATACGGGAGATCAAGGCTATAGTTGGCACAAAGAGTGAATTGTATTGCATTTTATTTTTATGTACTTATGTTATAAAGAACAATAAAAAAATTaTCTTAAAATATTGTATTATATTTAAAATGTAAAAGAGGTGTTTTGCGATAATTTTTCTATTGTTTCTTTTATACAGATATGTAAAAACGAATGCAATGCCAACTCACCCCTTGCATCAATTAGATACGGTTTTTCCTACATTGCAATAAAATTTAAATTAAATTAAAATTAAAACTATTAACCATTATTGATTATTATAAAAATTAAGATGTTGTGAAAAAATGTGATAGTAGCTTGAATAATTTGTGGAAaTGTAATACATTAAATTATAAACTTGATTAAATAGGTTACCCAAGTATCTTATGTGTATCATGTTTAGGATATGGACTTCTCTTAGAACTCATCATGTCTCACAATATACGCATCGCAAAACAGAAATTATCATCTATGGATCGAGGGTAAGCGTCATGGAGAATCAAACGGCTGATGATTATGAGGACATTTACCAATGGAACCACACGGTCTCGGCGGACGAAGGAGATACGGAGACAGGATATTACTTACCCAATTGGACCGATCTTATTCTAGCAGGATTATTTACAATGCTAATTATTGTTACCATAGTAAGCAAACATACTACTCAGTAACTGAAATTTCTAACATTTGTAGCGCTGGCAAGAGTATATTTTACATGAGAATATCTGCTTTAATACGTTGGACGCATAAATATTTTACTAAGCCAGGATGCCTTAAGTGGTTTAATAATTTGCATTTTTAAATCTAAAGAACAGCGACTTTTACAGATTTAAATAAGAGTTTACTTCGTGTATACATTATCTGAGAATAATTCTAATGTATCCATGTTCTCATGTATTTTCAATAATCGTGACCTTTTCGTCGTAATATTACAGGTCGGCAATACTTTAGTGATCGCGGCTGTAATTACCACGAGGAGATTACGGTCTGTGACTAATTGTTTCGTGTCTAGCTTGGCTGCTGCAGATTTACTGGTCGGTCTAGCGGTGATGCCACCGGCTGTACTGTTACAGGTACGCATGTGCTCGTTAGAGGATAAAACGCAATAAATGAACGCGAAATGTCCAATTCATCTTCGATACTAAGCTATGAGCCTTCATATAAGCCGATGCAATAAAAGCTCATTTAATTATCGTAATTGATATGCATTATTCACGAAAAGAAATAAATTGCCTGACGGTAAAGGTATTTAATAATTTTGTGAATAGACGCGTATAATAAAAaCAATGACTTTTAGTCAACCTTATCTCTCTCATTATGCAGAAAGAAATGCTCTTTCTTTCCTCAAACTGCAAATCGCATTTTCATGCGTCTTATCACATGGGATATTCATTGAAGCTTACAGGAGGAACTTGGGAGTTGGGCGAAATACTGTGCGATTTCTGGGTCTCCCTCGACATTCTGCTTTGCACGGCCAGCATTCTCTCGTTATGCGCCATATCTATAGACAGGTAAATCCGATCATGAGCATTTCTAAATCACGTCACATAGATAACGGAATTACCGGAAAGCTATCTTGTCAACCATTAAATCTTTTATAGAATAACAGATTATTCTATTATTAAGAAAAGAGATTTCTTATGAGACATAAATTCTTCAACATCCGGGTTTCTGATGGAAAACAGCAGCAACTATGTAGAACAGATGGATTTTCCAACAAAAaGGAAAGTTCATTTAAGTAATAGTATTCTATCAAGTTGGTTTTACCATCGATTAAACGATTCAACATTGATTAGTAAAAGCAGTTCTCGTATCTTGTACATCTTTTTTTCTCTATACTTGTATATACATAATAGGAATCTTTTTATTTTTTtATTTCTGTATTACATAATTTTCTTTTATGTATATGTATTAAAAATGTATAATTAATATGTAATTTTATAAACATATAAAATATTCTATAAATCTTTTATTATAAAAATGTAAAAATTTTATAAAATTGATTATATTATTACCTGCTATATAAATTGATAAAAAATTAACATCAATTTTACCTGATTTAAAAAAAAaCATGTACAAAATAAGACATGATTTCTGAAATTTTGGTCTATTAATCATTTTAGCATTTACTTTCGTTACTAAACGTAGCTTACATATTATAAGTACCTATAAATATAAATATAAAATATTGATGAGAGATATATGATTTATAGGCGACTGATATGCATTCAGCAATTCTCCTCTAAAGATCAAACGTTTTTTTTTACAGAGCATATAAGTTAAATATTTTACTTTTCACATTTGCTTAGAAGCTTTTCACTCATCGCATTAATCATGTACAGATTACGCGAATAAATAAGTTGAAGTTATTACGTATTACGTTTTAATATTCGTTGCGTTTCAAAAATACAATTTTGATACACGCGCACATGTTTACTCGATGCTGTTTAGCTTTCACGGTAGAGATCCTCCTAAAATCCCGAGACGATTCGTTCAACACGCCTTTTAGCCTTCCATTTTCAAGACATTGCGCAAAACATACGATATCCTGCACTTCACGGCGATTCTGTACGTGCTAAGGTAAAATCGTGCGGAATTTATCGTGCCATCGTCGTTATTCCTCGTTCAAGGTATCTGGCCGTAACTCAGCCGCTGATCTACAGCCGTAGACGCAGAAGCAAACGACTGGCTGGGTTGATGATCGTCGCGGTATGGGTGATGGCCGGCGCAATAACGAGCCCGCCTCTACTGGGCTGTTTCCCACGTGCGACAAATCGAGACATCAAAAAATGCTCCTACAATATGGATTCCTCCTATGTGATATTCTCGGCGATGGGCAGCTTCTTCCTGCCGATGCTGGTAATGCTGTACGTGTACGGCAGAATTTCGTGCGTCATAGCGAGCAGGCACAGAAATCTGGAGAAGACCAATGAGGGGGAAAACGTCCGATCACGTCGTAAAATCACGGTGAGAACTGTTTGATTTAGTTTTCCTCAGAGACATAACTATATATCTCCAGTATAAGTTCAGTTTGTTGTTCTTTTTATTTACGTAACTTGTTCTTATTACTTTGCTTTTATTGCTTTTATTATTTTGCTGTATAATCCGATAGAATTTAACAATGTAACTGTAACGTGCTCGTTATAATTAAAATAAACAAGATTTTCTATTTAAACAAATTTATCATAAAGAATTTTAGACATTAATATTATACAAAAACAAATTACGTTTGTTTTATGGTCCGCTTTATCTTATAACGTCATTTATTCAAATGATTATTGAAATCAAATGCTTATAGGAGTAAAATTTTTAATATGATTAATATTACATAACACGTTTCCCTATGTTAACAACTGCCTACACATAAATCTTCCTAATATTACGCTTTGTTTATTCTCTCGGTAGATGATATTGTAAGCGAATTTTGACAGGGAGATATTAATGACGTGTTGTTGAAATTCTACTCGATCAATACTTTGATTTGCGATTATATCTCATTAATAATAAACGATTATGAAAGTTTATAAAAATGCGTAATATTGAAGTCTGCGTGTAGATTTATTATAAATAACTGAAAACAATCTGCTTCCTCATTTCTTTAAAAAAGCTCCGAAATACTCTGTTATCGAATGAAATGTCTTGATGTTTATTTCACAGACAGAAAATGACGGCCTTCCGTTTCTTTGATTAAAAATGACATTTACGGTGTGCATGTGCAGCGATAAAATGAAAAAGCTGGACCACTAGTAATCAGAAAAATTGTTCGCAACAACGAGCAACAGTTAATGCAGATGGGATAACAATCTATTCTGAGTTCAAAGCGAGTGCGCATTTCCAATCGGGGAAAAAAGCGATAAAAACGTATCCTGCTTTTAATGTAAACTGTACCATGAATCCAATGGCACGATCAATCAAAGATAACGAAACCGTTCTCAGTTTCACTGAGAAAGAGATTAGCGAAACCGACGGCTCTCTCACAGGCAAGACTGGCATAGGCATTTAATATCATGATGGGAAATGGGAAAGCCACAGATTCCCCATAATCCACATCATCCGACTTTATATAATCGATTATCAATCATTTTGGACAACGTCTTATCGGCTTTATCGAATTTGATTTAGGTTACGTAGTAGCAAAAACATCGTGATTTTAATACAAAAAAATTTTCAGTACATAAGAGAGAAAAATAGAGGAAATTACGAGGAAAGAATTTTtCTTTtATTGTTTATTAATAATCAAATCATTAATGATGAAAATTAATGGTTCAAAGTATGAAATGCGTATAAATTCATTGATTATGTGTATAATTTTTTATTTATAACAAACATGATCTTTTTAGAACATACGTACTGATTTATAATAGTAATACTGTTTTACATTGTGAAGCTGAATGAAAATAGTTTAGAAAATGATGCTTTCAGTTACAAACAGAACAATACGAGTAGACATTGAGCGATTTATTACGCTGGCAGAATAAGAAATGTTTAAAAGAATAAAAAAAAaGAAATCCGATTGCGGTTCGTAAAAGAAAATATTCTCACTAATACAATTTTTTtACTTTGAGGATAATGAAAAATTACAAAGCTCTGTAATTTAATTAGGTAACTTTTTCGCAATAACTGGTGATGAGTTTCAAACTATTACACACCATTTAAGCTTGGCCAGACTTAAATCGTTAAAGAAGGTTTAAATTGATTTAACAAATCCTTTGTATATATAATGTAGTAATTCTTCATATATCGTATTACTATTGCATGAAATCATTTTTCTGCAGATTGATCGTGGTAGAAGTATCAAGGCGCAACGTTCGAATTATGCTGAGAGCGGAATAACGTGCGACAAGCCATCCGAGGATACCGAGCTAACAAATATGTGCAAAAAGTTGGGCACAATTCGGGGTAATCAGCAAAGCTGCATCAACAGGGTCGCCAGGGAGACGAAAACTGCAGGCACCCTCGCGGTGGTTGTAGGTGGTTTCATCGCATGCTGGTTGCCGTTTTTCATTCTGTATCTGGTAACACCCTTCGTGCCCGTGCAGCCGCCCGATGTTCTCATGCCAGCCTTGACATGGCTAGGTAGCTTCTCCTTTACATACGACGTTCCCAGATATATGATGTTCCTATATAGGACTCGTTTTCCATTATTATTTATGGTTCAGCGAATTTGGACAATCCGTAAAAAATATCTGGAATATCTGGAATTGTTTTAATATTTGTTTTATTTCAGATTATTTAAATAACAATTATGTTTAAAATTAAATTTATTTTATATATGTTGAAATGAAAATAAATATACAGATTTATTAATAATATAAGGAATAAAAATAAACAAAATTAAACGCATAGATTTATTATTAACATAAAGAATCGACATAAACAAATTAAGTAAAATGCGGTACATTTATATATTTATGCATTATGCTAACGTTTGTAATTTTTAATTAATTCCGTTGTAATGTCTTTCAAAATTGCATAATTATTAAATTGTTATTTTGATAAAAAAATTTTTATATGTTTAGGATGGATTAATTCGGCCATCAACCCATTCATTTACGCTTTCTATTCAGCAGACTTCAGACTCGCTTTCTGGCGACTAACATGTAGGAAATGTTCAAAGAGTAGACTGAACTTAGATGGCACAAATCGGAAATTACCAGCCTCGGTTAACTGGAAGAAAGATACATCGAGGACGTGAAGTTCTCTGCCCACAGTTTTGAACTTATGCAATTATGTGGCGTCCGGTATAGAATGATTGTGGTTGACTCGGGTTTATTTGCAATAGCAATCTATTAGCAAAGAATGATGTGTGTGAGAACTACGTATGTTCCTAGTATAAATTTATAACTAATCGATATATGTAGTTCTTATGCGATTTTATAAAACATAAAAGATTCACTATGCATATGTATACGCACAATCATTTTGGATACGCGTAGCTTTCAAGATTTACATCAACAGTCATAATCTCTTTGTGCAATATAATTGAATATTATTCTTTTATTGAATGTTTATCAGTTTTGCAATTATGTTTCATTAAATTAAATTTTTAAAAAATGTTTTACAATTGTTTAATAGTTTTTTtAAAGTAAACTTTAGGAGATAAATTTAATGTATATTCTTTTATGCTTTTTTTtACATGTGTATAATGCAGTGTGTCAAGGCAACATTAAAAACATTGAATCAGTATGAAAATCTTGGCTCTTTTTAATGTTTTTTCTTAAAGTGTGTCTATACTGACAAATATTATGGCAAATTAAATATTGGAAAAATGACGTCAAAGTTGTCTATAACAAAAAAaTTGATGCCATTTGTAATGCAATTTTATGTTAGCAAAAATGAGTCTGACAACAAAAATATTTGAAAAAATGACGAATGCAGTAAAATGCATATGTAATAAATTTTGAAAATTTTTAATTTTtGTTTACAGCATTTACAACTTTGTTCCCTTCAAAAATGTGTACATTATAATAGCACGCAAATATTCTCTTTTTAAACTCATTTTTACGGATATAAAGTAGCACAATAAATAACTTAAATAATACTAATTTTTTtGTCATATACAGCTTTTGACGTTATCTTTATAACAATGCATACAGAGTGTCTTATAACTTTTAATTAATTAATATTTTGAGAAATGAAAGAGGATGGAATATGGAAAAGTTTTTTTtCCAATTTTAGCTCAGACCATTTACCGAGTTATTAACGATTAAAGTTGATCAATCAGATTGCGCCTGTAATACGCAGAAGCATAACATGTCATGGGGCTTCTCGCGTTTACATTACATTTTTCCAATTAAAATTTTATTCTAATTCTTTGTATTAATAAGTAAATCAATAAATCAATAAATAAGTAAATAAATAAATAAACATATAAATAAATAAGAATAAATTACAGTTAGAAATTATTTATTTATTTATTTATTAATATAAAAAATTAGAATAAAATTTTAATCGAGAAAATGTACAGCAACCGCGACCATCCTCATGCTATGCTACATTTCTGCGTAGTCCGGATAGGCGCAATCTGATTGATTAACTTTAATCGTTAATAACTCGATAAATAATGATGGTATGAGTTAAAATTGCGAAAGGAACTTTTAGTTTAAAATTCCATTCTCTTTCACTCCCTGAAATATTAATTAAGAATTACGGAACACTGTAAATTTGCTTAATATCTGCTAGCGTTGACGTACTATAAAAAAAGTAATATCATCTTTTCAAAAAGAGTCAAGATTTTTGTATTCACCTAATGTTTTAATATTATGTGCAATGTATTGAATATTTATATTTATATAAAAAAGTGTAAGTAAGCTTGAATGAAGAAACACACTCGAAGTATGTAGCGAATTCTTCTGGTAAAACATATGACAATTCAGAAATAAAAaTATAAAATATTTATAAGTAATTTATGAATATTAATATTACGTAATTAATGCTTAATCTCTCGTAGAAAACAATGTACGACTGACACTTAATCTGTGATCAATATTAAATCTCATCGTTAACGCATTTATTCGTGATATTTGTATACGAAGAATAAACGATTAAAGATATCTTTCCTTAATTATCATATTATTGCATTCGTTCTATTTTTCTTTAAACATTATGCAAATAACGCCAATATAAAACTTCAAGCACATGTACTGTATATCTTTGAACTTACGTCTTCGAGAAAAACATGCTACATGCATCGAATGCTTTATACTAATACTTTGGCATCGTTAATATGTGATACTACCTTAATATACTAATTTATTTATAATTATTTATAGACAGTGAAGTAATAGCAAAACGTAATACATACTTAGTCATGTGGATTTATAAATGTGAATAGAAATTTATAAATAGATTTTAAAAGATATTTAATTATATTTTAAGAATATTAGATAAGAAATCATAAAAATCCATAATTTATTAACATATACATAATACTATTATATTTAAATAGATATTTGAATTTTAAATAGAGTTAATTGAGATGGTAAATACTGCTGCATAAATTTCATACATTATATAACTTTATCGATCGCTGAAGACTGTGTAGATATTGTATGTGACAGACTATGCCGAAAAATAGAATAGAATTAGTGAAACGTTTGTTTTCAATCGGTTATTTATATGTATAAACATCGTATATAATAATATATAATATATATATGTATATAATTTTAAATTATTAATGTATCTTACTAAAAATTTTTGTTGCACATACGTACATACATAGAACAAGTTTTAATAGATGTATATACATATATAAGATCTGTTTTTTACATATATAAGTCTTTATGAATCGCTATTAAGTATGTATTATTAATTCTAGTCAACAACGATTTTGCTTTATGTAAACTAGAGAAGGAAAGTATATAAATAAGCTGAAATTAAGAAATGACGTGTTTCTTATTTATTATCTTATGTAAGTTTCATGATATGTTAATATTACTATGTAAATTATATTGTCGTGTGTAATACAGAAAAAATATAGTTTTTCTTTGTTTATTTATTTCTAAATTTTTATTAAAGCAAAAGAAAATATTTATATTATTTTATTACGACTTGTATCTTAAAATACATATTTATAATATTGAGATATTTTAGTTGAAATGCAAATTAATAATGCAATTATACATGGTATTTAAACTATCTGTAATATATAAAATGCGTAGAGATTAGAGTTGTGAGATCATAGATCATGCAAACATTAAATACACACGCCTACAAAAGAAAATATAGTGATAAGTCACTAATACAAACTACGATTGCTGCAAATACATAATATATAAATTGCTTAGATATCTAGATAGCAACGTGTCTGTATTGCAGGCTTTGAATCTTAGTTTGTTAACAAATTGTCATTACGATATGACACACAACTTTTGATAGCAACTTGCCGGTGCTTTGTCGGCAACTTTGAAATCATCATCATGAAAATTCATACAGTTGCCATTATGTTGCTATAATAACTACAGGGTTTATACAATGCTGCCATATTGCCAATAACATGAGGTAATTTTTATGCAACTAACTTACCGTAAAACTGCTGGCAATGTATTTATACATTGTTGTCTATGTGTTGCTTGAATTCGAAATTGTCGAAGACAAATATCTGGCAAGTTGCCAACATTATAAGCAATCACAGATTTAAGCGATTTTGCTGAGACACAATTTGCTATCTGTGTGATTTACACAATTTAAGAGTTTTTAATATATACAATTTTCTTGCATAAATACATTTTTCTGATTACTTTGTAATCATTTTTTTAATATTTATAGATATTACATCAGCTAATCAGGAGTTTGAGTTTGTCACTGCTATGTATACTTTAAAGCATTCCTAATATTTTGTCTATTGACATATAGATAAAGTTTGAAAAATAGTTTTATAAGTTTATATCTAATAAAAATACTTAACTAGAATAATTATTATATTAAAGATACATAGAAATTTTTACGTATATTTGTTAATTGCGTGTCTTTATTATATTGCAAATATAATATTTCTGAAATATAAATTAAAACAAAAAGAACATATATCTTAATTAACATTTTTGTTAATTTACTTGTTCTATTTATCAAGATTTTAGAGATGATATTATAAATAGTAGTAGTAGAATGAAGAAATTGATAATTCTGATCCTTTTTCCTTTTTAACAAAATTGCTTTATTGAATCAAATTTATTCATAGTATTATTTTAACATGTCAATACAAAAGAAAGCTGTATAATTTTATTTCTTTATTTAAAATGCTATATGTTGCAAATTTTCATATAATGGTTGTATGCCAGCTGTTTTTAATTGCATTTCTTATGCTCCTTCGTTAGAATCGGCGAGCACAGCTTCAGCTGCTAAGACACATGCTACAAGGAGCAAGCTTTTGTCACATTTATCCTCCATGtCTTTTGCTAAAATAGAAAAAAAAaTAATTAAGTTACAAAAAATAACATATTTTTtAAAATTTATTATAATGTTTAAATAGCCATAATGTATATAAGTAATACTATAAAACATTTTATTAAACAAAGTTAACATTTCTTATATAATTAACGGAATTACTCTTATACGTATAATTTTATAACTTACTTTCTAATTTTATAACTTACTTTCTTGCATGCAGGCATTCAGAGCTTCTATCCTTTGATCTCCTGGTTGAGCACCTGTTTCCTTGATATAGTCCTCACGCATTTTCTCTTCATCATAATCAGCTCCAGACATCTAATATTTACAAGAAAGACAAAAACGTCAATAATTTGAATACATTAGATTACGTTTTAAAATAAAGATAAGATATTTTGTACTATTTTTTGAATTAAATTATGTTGTATAATGTGATAATATATGTATATAAAAATATTAATTTTTtAATAAAATTAATGATTGAAATCAATTCTAACAATAAGTTAAATAGGTCTACATGGGAAGACGTTATGAAAAAAATTATATTTTTGTTTGCAATGTTTTATTTTCTTATGTAATAGTTTGTATTTTAAATATTCTCTTTTTTATAGAAAATAATAGCTACTTACCAGTCCATCTTTTTCTAACAAACATTGCATGACGCAACCATTTTTGTGTAGTTCGGTATCTTCATGATTGGTTTTGTGCTGGCCACTTGATACTTCACCAATCGAGAAGATGTCATCTAAAAAATAAATTTAGAAAATATTAAATTTGTATCTACTTAAATAATTACAAAACACGACTTATACGTTAAAAACTATTGGGATTTTAACTCAAACATGAGAGTGCAGTGTGAACACAGACGTGAAATAATCTTATTGAGGCGGCCATAGTTAAAATCTCAATATAAATTATATAAAATTTATAAATTTTTTAAATGTAAACAATTTTTTAGATATAATTAAAATAAAACAATTTTCCTTAGATTTTAAAATTTATATACGTTATGGGATGTATTTTTAATAAAAATCTTGTATAAGTAATTAAAATATTTTATATTTAATACAGTATAGAAAGCTGTATATAATATGGAAATAATATATAATACACTTTTATTATAAAGGTATTGGTTCAAAATCAAACATAAAATATCTGTTTCTGTACTTTATGAATTAAGAAGACATGTAAATTGTGTAAAATTCTCTAATATAACTTACCCTCTGTTAGACTATGTTCGGCTAAGCAAGTCGCGTAATTGTCATATTGGGATCCTATCTTCCTCGCGCTATCACGAGATGCAGAAGCGAAAGCCTAGATTTGGAATTTTATTTTGCTTATTTTAATTAAGTTTTATTTCATGCACAAGTATAAATAAACGTAAAATATTATCTTCTTATAATATAAACAAACGTGTAGACATTATAATATATGTCTACATGCAATAAGGGCATTGTAATACTTATAATTTATTTATAATTAAGTTGCAAAACACATTATTGTATTATACATTACTAAATTAAACAGAAAAATTTTATACTAATATTTAATTATTATAAAATAGAACTCACCACGAGAGCAAAAATAAAAATATGCAATACGAACGTCTTCATTATTAAGGCAGTTATTCTACTGTACTTTGAATGTACTAATATAAGAACTAAACGCTAAATTCAAATCACACCATATTTATACTATCTGTAATATATAAAATGCGTAGAGATTACAGTTATGAGAGCATAGATCACGTAAACATGAAAGACACACATACAAAAGAAAATATAACAAGTTACTAATACAAACTTTGATTATGGCAAATATAAGTTGCTAAGATGTGACTTATTCGTGGAAAATTTTCTTATATTTACAATTTTCTTACATAACTACATTTTTCTGATTATTTTATAAATTTATATTACGTCAGCTAATCAGGCGTTTATCTTTGCCGCTGCTACGTATACTTTAAAGTATTTTTAGTTTTTTGTTGATTAACGTATCGCTGAAGTTTGAAGAATAGTTTTAAGATAAGTTTATAGAAAACAGAAATACTCAGATAGAATAATTATTTTAAAGATACATTGAAGTTTCCACCTAAAAGTAAAAAATCTAGCTAATTATATTACAATAAAATTTAGGACAGCTCTTTGAATTTTGTTTCCCTATTATATAATTATGTACATTAACTTATATACATTAATTGAGAACAATATGTGTATCATTGTATAGAAGTTATTTGTAACTATGTGAATTATATAATTGATGAATGTATAATATATAATGTATTTATATAATGGATTAATGTATAACATTTATTTAATTTTATTTtTTTTTtCTAAATAATTATTGTTTGAATGTTTGTGTGAATATTTTTCTTAAGAAATACGTTTAACATTTGGATTTTGAGTATTAATAAATAACTCATATTTTAACGTTTAATGCATTCTGATATTTTTTGAGATCAAGATTTTACAGATAAATTACGTAAAAAATAAAACAAGATTTTTTTTACATTTTAATTGAAAGAGTTTTAAGTTATGTTACAAAaGAAAGATTTATTATTTGTAGATGTCATAATATAGTTATAATAAGAAGTAAGAATAATGTTGTAAATACGGGAGAGAAGACATTTGTGAAATATATAATGCCTATATATAGATGTGGGATGATGAGATATATATAGATGTGGGATGATCTTGTACAGTTTTCGTTGAACTCTAAGACTAAATGATAAACTACTTTGTTAAAGTTATTTAAACATGATAAGATGTTTACTGGTTATTAATGTTTATTGTGTTTTTATATAAACTGAATTTTAGTTTTGTAGGTAGCAGAGATTTTTACAGGTGCATGTTTTTTACGTAATTTTTAGAAGCATGTTGGGTATTAATTTTTTAACTTTAGTTTAGTTTAAAGCTTAAATATGATTTTTAAATAATGTAATCATGTAATTGAATTTAATGTGTGACGTAATGTGTTTATGAATCCAACATATAAAGTTATATTATGTACAGGAGAAGGTCATGGGCCATTTGCATTATGAATACATTTGCGATTTTACTATCGCATTCTAGACATTGCGGAATATTTACTAGTGCAGCGAGTAAGCAGCGAGTAAATAATTTAAAACAACTATTTTTTAAGTCAAAGAATTATTTAAAAAAAGATGATTTTTTGTAGGTAAAAATATATCCTGTGAAATATTTACAGGTTAAATTGAGGTATTATGGCTATAAGGAAAAGATGGCCATAGTCTGAAATTTCTTCAGTAATTGCTAAATAATCTATTTTTATAGTCATTTTGAAAGATAATCAATATTTACAGTATTTTATATGCGTACACTATTCGAAACAATTTTATTCTGAATATTATATAATACTTTTACTTTTGACTAACCCCCTCCCCCTCCTTCTGCAAAGTTTTGCATGTGTTCTCTAAAAGCTGCTATAACGTCAAATAAATTACTGTTAAGCTATCATAATTAACGTTACGTATATAATAAAGGAACTTAAATTGTAACATGACATATAATTTGTGCTTTTATTCTCACTATTTATTTAAATGCACTGTCTTCTTTTTCTTACATTTCGGCTAAGATAGCCCACCTTGTTTTTTCATACATTGTTTTTCTTTAAATTATAGAAATCTGTTTTTTTTTCCTtATTTTAAAAAAAaTTATAATTGTTATGTTATTATTGCAATATtATAAATATAACTAAGTTATaTATAATTATATATaTAAAAAAAatATATATATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGtGtNNNNNNNNNNNNNNNNNNNNACTAAATATATAAAATTATAAGTTTTATTTATCACTTTAGAAAATATTACATTTATTTTtAACATGAAACGTGTATAGCCAACTGTCCCATAATACTATGGCCATCTTTTTTtAAAaTTTtGGTAAAATGGCTAATGCATTTGTTATAAAATTTTTTTTtAATATTTGATTTCTAATAAGTGTTTTCTTTTTAAATTCAATAGTATTATTAACTTTAAGATTCAGTGAAGTGATATGTCAAACATTATTAAAAATTAACAAAAATAAAAATGAATTTTTTGCATTTTGAAAAACTATGGCTATCTTACCCGAGTGTACCTTAAACTTGATCATTTTGTGGCACTTATTAGTGTGCAAGATTAACAAAAGGTCAATAATTTATGATTTTTTATAAATACAAAAGTGTTTTTTGTGATATTAGTACTACGGTTTCTCTTCTATCTCACAAATGCATTCTTTTTTCTCTCTTCAGTAAATTGTAAATTACGTTTGATCTATACATTCGATGTGTGTATATGAACTTCTCCCGTATACAGAAGAATGTTCCAGAAAGCTCGCCTCTCCTTTTATGAGCGGATTCTTTAAAAAATTCTAAGAAAAAAATCCTAATACAAAAATGTCGAGGGTATAATGGTTTTTAAATTATTCGCGATTAAAGTTTACGAATCATAGAGCTGACATTTAGCGCGCTCAGGCATGGCGACATGACAAAGTACCACAAGGGTACCTTTTGACATTGAAGTTGTTATATAAATACGCAGTAATATTTATATTAAGAAATTATGACTGTAGCAAACATATTTGTACATTACATGAGTATAATTAACGTTTTCAAGAAAATATTAGTTCAATAACAAGATGTTACGATAGCCGTTGGATCAGTTGTCAAAATCAATTCATTACCATGTTCGACAAGAACATAAATTACAGCAAATATTGTGTGCAACCTATACTTGAAAAAACTGTTTACAAATAGGTACAATCAGTCTAATAGCCAAGTACTATAAATTTAAATACAAATTGAAAATATTGCAGTAAAATACTAAATTAAAGTAAACAATAAAACGTTGAATAAAACTCAATTAATTTCTCTTTAGTGTAATCAGAAGTAATGCTTTTGTTGTACATGTGCGTTGGAAAAGAATTAGTAGAATTATAAAAATCACAATAAAAAAGGTATTTCAAGAAGATTGTATTCATGTATATCTAAAAATTTTTTAAAAATTGAACAAATGTATTAGATATATACAAATGTATACAAATCTAATTATAAATATAACTAATAATTTAATAATTTCTTATCTGGTGTCCGCTAAAACTTCTTGCGTCACAGCGTATAAATTGCTGCTTTCGCGGATATCGAAACGTTATGGAAAAATGACTCTGCTAGCAACACTGCTCACACTTACAATTAGTCTCTCATTCTCTTCTCCTTTTGTCCCCCCTTTTCCATCATTTTTTTCCCTCTATCTCTTTCTCTTTATTCTTGCTCGAGTTTTTCTATTTCTCGTTTTTGTTTTTTTCACATTGTGTATTTTTCTCTTAAAAAAATTTACTTTATTTTGTTATTGACATATAGCTAAAGTTTGAAGAATAGTCTCATAAGTTTATATTTAATAGAAATACTTAACTAGGATAATTAGGGAAGATCCTTGTACCTTGGGACATTTTTCTTTAAACCTTCATAATTTAAGTTCAAATTGATCTGTAGCTATGACTATTGATTATTTCTATTAATAATTAATAACATCACTCATTATGCAACACGCGACTCTATTATATTTTATTTATGAGAAAATGTCAATTAATTACTTAAAGATATTTATCCCGATTAAAGTAAAATCGTGATTTGTACTTTGGGACACTATTATTTTTTTACCAAATTCTTTTTTTTTTTtGTTCAACTTCACGTAACGGTCTATTAAAGATTTTGAGACATGGAACTCTTCGGCTGCATTCCGAATAGAACAACGTCTATAATGATCATTTCAATGACATTTTTAACATTTTCCTGAATTGATTTTGATTAGGTGACTTTATTTTTACTTTGCGGCATCTAAAAACATAATAAACAAAAATAAACAAAATAATATTGAAATAAATAGTTGAAAAAAGCAGTGCCTTGTACCTTGGAACAGTCTCAAGGTACAAAAAATTCACTGACCCAAGGTACAAATTTCTCTTGTATAAAATAAAGTATGGTTATAATTTTTAAATACAAAAATCCAGTAATTTTTATTAAAATAATTGGTTACAAATGTAGTTATCAACTAACTGTATCTTAATTAAATTACTCACTTCAAAATATTTTGATTAAAACAAAGATTCAGAAGAATTGTAAAAAAACAAACACATGTAAAAATCACACGACGTGTCACAGCGATGAAATAAGTCAAAATGGCCGACTTTATGTCATGCATTCTGAATGTTGTAATGAAAGAGCTACTAAATGTTACTACTTATCACTTTTTAATGTGTAATTTTTCAAATGACGAGCTTGTCCTAAGGTACAAGGCGTCCCAAGGTACAAGGTTCTCCCCTATTACATTAAACATTAAATGATAGTTATATAAAAATTTCTACGTATATATGTTAATATTTACGTGACTTTATTATATTGCAAATATAATATTTTTGCAATATAAATTAAAGGATATATATTTCAAATTACATTTTTGTTAACTTACTTGTTTTATTTATCAAGATTTTAAAATGGTATTATAAGTAGTAGTGTAAGAATGAAGAAACTGATAATTTTGATCCTTTTTtCTTTTTAATAAAATTGCTTTATTAAATCAAATTTATTCATAGTATTATTTTAACATGTCAATACAAAAAAACGCTGCATAATTTTATTTTTTtATTTAAAATGCTATATGTTGTAAATTTTTATATATTGGTTGTATGCCGGCTGGTTTTAATTACATTCCTCATGCTTCTTCGTTAGAAGCGGGGAGACTAACTTCGTTCATTAAGACACATCCTATAAAGCCCAAGCTTTTGTCACATTTATCTTCCATGTTTTTTGCTAAAATAGAAAAAAAAaTATAATTAAGTTACAAGAGATAACATATTTTTTTACATTTATTATAATGTTTAAATAGCTACAATATATATAATAAGTAATACTATAAAACATTTTATTAAACAAAGTTAACATCTTATATAATTAAAGGAATTACCCTTATACGTATGATTTTATAACTTACTTTGTTCCATGCAGCTACTCAGAAAATCTATTCTTTGATCTCCTGGTTGAAGACCTTTTTCCTTAATATAATACTCACGCATTTTCTCTTCATCAAAATCCGCTCCAATCATCTAATATTTACAAGAAAGACAAAAACGTCAATAATTTGAATACATTAGGTTACGTTTTAAAATAAAGATAAAATATTTTGTATTATTTTTTGAATTAAATTATGTTGTATAATGTGATAATATATGTATATGAAAATATTAATTTTTCAATAAAATTAATGATTTAAATCAATTCTAACAATAAGTTAAATAGGTCTAGATGGGAAGATATTATGAAAAAAaTTATATTTTTGTTTGCAATGTTTTATTTTCTTATGTAATAGTTTGTATTTTAAATATTCTTTCTTTTAGAGATAGAGAAAATAACAGCTACCTACTAGTCCCAATTTTTCAAACACACATTGCATGATGCAACCATTCTTGTGTTGTTTGGTATCTTCATGCTTGGTTTTGTGCTGGCCATTTGTTACTTCACCAACCGAGAAGAGCTCATCTAAAAAATAAATTTAGAAAACATTAAATTTGTATCTACTTAAATAATTACAAAACATGACTTAAAAATCTTTTATAACTAATTGAAATATTTTATATTTAATACAGTATAGAAAGTTGTAATATGGAAATAATATATAATACACTTTTATTATAAAGGTTTCGGCTTAAAATCAAATATAAAATATCTGTTTCTGTACTTTGTGAATTAAAAAAACATGTAAATTGTGTAAAATTCTCTAATATAACTTACCCTCTGTTACACCAAGTTCGGTTAAGCAAGTTTGGTAATGGTCATAGTGGGATCCTATCTTCTTTGCGCTATTACAAGATGCAGAGGCAAAAGCCTAGATTTGAAATTTTATTTTACTTATTTTAATTAAGTTTTTTTtACACAAGTATAAATAAACGTAAAATATTATCGTTTTATAATATAAACAAACGTATAGACATTATTATAATATATGTATACATACAATAACGACATTGTAATACTTATAATTTTTTTAGAATTAAATTTCAAAACACATTATTTTATTATACATTACTAAATTAAACAGAAAAATTTTATACTAATATTTAATTATTATAAAACAAAAAGATACTTACTATGAGAGCAAAAATGAAAATATGAAATACGAGCGTTTTCATTATTAATGCAGTTATTCTATTGTACTTCAAATATACTACTTAGTACAAGAACTAAACGCTAAATTCAAATGACACCATATTTATATTGTCTGTAATATATGAAATGTGTAGAGGTTACAGCTTGTGAGAGCATAGTTCACGCAAACATGACAGACACACATACAAAAGAAAATATAACAAGTTACTAATACAAACTTTGATTATGGCAAATATAAGTTGCTAAGATGTGACTTATTCGTGGAAAATTTTCCTATATTTACAATTTTTTtACATAAGTACATTTTTCTGTTTATTTTGTAAATTTATATTACATCAGCTAATCAGGCTTTTATCTTTGCGGCTGCTACGTATACTTTAAAGTATTTTTAATTTTTtATTGATTGACGCATTGCTGAAGTTTGAAGAATAGTTTTGAGATTATTTTACAGAAAACAGAAATATTCTACTAGAATAATTATTATATTAAAGATACATTGAAGTTTCCACGTAAAAGTATAAAATCTAGCTAATTATATTACTATGAAAATTAGGAAAGCTGTTTGAATTTTGTTTTCCAATTATATAATTACGTACACTAACTTATATACATTAATTGAGAACAACATGTGTACTATTATATAAAAGTTATTTGTAATTGTGTAAATTATATAATTAATGAATGTATAATGTATAATAAAATTATGTAATAAATCAATGTATAATATTTATTTAGTCTTATTTTTTTtCAAAATTATTGCTTAAATGTTTGTGTGAATATTTCTTTTAAGAAATACGTTTAACATTTGGATTTTTAGTATTAATAAATAACTTGTACTTTAACGTTTAATGCAGTCTGATATTTATAAAATCAAGATTTTACAGATAAATTACGTAAAAAGTAAAATAAATTTTTTTTACATTTTAATTGAAAGAATTTTAAATTATGTTACCAAAAGAAAGATATATTATTTGTAGATGTCATAATATAGTAATATAGTAAGAAATAAAGATAATATTGTATATAGAGAAGAGAAGACGTTCGTGAAATATACATATAATATATATAAATATAGATGAGATCTCGGGGTGATGAGATCTTGTATAGTTTTCGTTGAACTCTAAAGCTAAATGTTAAAATTACTTTGTTAAAGTCTATTTAAACATGGTAGAATGTTTACTGATCATTAaTTGTGTtTTTATAAAAGTTCATTGTGTTTTTATAAAAGCTGAATTTCAGTTTTGTAGGTAGCAGAGATTTTTACAGGTGCATGTTCTTTACGTAATTTTCAGAAGCGTACGTAATTTTTGTTGGTTATTGATTTTTTAACGTTAGTCTAGCTTGAAGCTTAAATATGACTTTTAAATAATTTAATTGAATTTAATGTGTGACGTAATGTGTGTATGAATCCAGCATATAAAATTATATTATGTACAGGAGAAGATTATGGGCCATTTTCATTGTGACTACTTTCGCGATTTTACTATCGCATTCTAGACGTTGCGTAATATTTATTAGTGCAGCAAATAAATAATTTAAAAAAaCTATTTTCTAAGTTAAAAAATTATCTAATAAAAGAACATTTTTTtGTAAGTAAAAGTATATTTAGTGAAATGTTTCTAGACTTGATCATTTTCTGGCACTTATTATTGTGCAAGATCAACGAAAGGTGATTAGTTTATGATTTTCTATCATTACAAAAGTTCCTTTCATGATATTAGTTGCTTACATAACTACCTATAAAATAATTGAAGAATTCTATGATTAACAAACTTGTATTCAATACTTAATTAACGCATGCTAATTGTTTACTTACAGATGAGTGTAATAAATCGAAACATAGTTTTTATATATGCTGCTTTTTTATTAATTTCAAGAAATTAAAAATAGAACATAGAAGAATACATGTACGTATATTTTTATTTAATGTAAGTTATATTGAAAGTGTAGTATATAAATTTATACTAATAATTACACAAATAATATTTAATATAATCCCTATATTTAACTGTGTTTATTCCGTCAGATTTTACTTCTATTTCTTTTCATTTGGTTCTTCTGTTTCTTCTCATTCAGTTGTTACGATTTCTTCATGTTCATGTTCTCTTGGGAATTTATCCATAGTTTGTATTATGCATTCGAATATAGAGAAACATTTAGCACATTCTTGCGTAATATCCCTCTCTATATAAATAAAAaTTTTTAAAATGTGATAAAAAGATGTCATAATATATAGTTATATTAATATGTAATCATAAATATATAGTCATATTTTCTCCGGATAATTTAATAGTTTATATATTGTCCCAAAATTTGCATCATATGTAAGTATACATACAAAAGAACATTCTAAATAAACTTTTGTAATACCACATTTTTTAAGATCTATAGTAATTTTTATACATTTATAATAATGGTGATACAATAAGACTTAACTTACTTTCTTCTAGGCATTTTCGCACAATTTTGCCCAATATCACTTTTAAATCTTGCCTAGTTAATTCATATAATCGTGCAATAACTTCGTCTTCTTTAATGTTTGTTCCTTCCATCTAATATAATTTAAAAAAAaGTATAAACAATAGAAAATAGTAGAATAGTAATTTATTTTAATAATTTAACTCATTTGAGAGTTATAGAAACGATAAAAATGCCTTTTATAACATTAGTATTGTTAGTATGCCACGATACCTCTACTCTCTTACAAACATATTCTTTTTTTCCTCTTCAGTAAATTATAAATTATGTTTGTTTTATATATTTCAAAAACTTCCATCCTATAAGGTAATTAATGAAACTCAACGGTTAACAAACTGGCATTTGTTAGAACTGTGCTGCATTAATATTTATTGATTTATTGTCAGAAAACGATAATTGTATTCCACCACTACCTTTGTTCCCCTATTTGTTACGACACATCAACCTTGCATTCATCATATGTATATATATGTGTAGTATATTTATAAACACTTACTAAATTTTGTTTTTTCAAAACACACGCCATAAAGCAGCCATTCTTTCTCGTTCTTTCTTCATTTCCTGGTTTGGTATGTACGTTAATGGATACTTCGTTCATACTGTACAAGCCACCTAAAAATAAAATTAATCAATGAGGGAAACAAACGTGTTTTTTTTtGTAAAATTGTTAACTTAATAAAACATAAATAAAATTATAAAATTATTAAAAAACGCAATGTTAATTTAAATTGGCCCATTGAAGTCAGGTGCCAAATTAAATCGGGTACAATAGAATTATTGCTATACTAATTTTTTTTAGAAATTAACTAAGTAAACTCGGATAGGAAACAGCACTGGAAATCTGCAATAATGTGCATATATAATGTGTATATAATTATAACTTACTGTTATTTAAACCATTTTCAATCAAGCAAGCTTCTAAATCAAGCCGTAGTTTGATCTCATTTTGGATCTCTTGTTGTATTTCTGTTGCGTTAGACAACTGAAATTTAGCAAAAAAATATTCTTATTTATTTTATGTATTGTAATATAAATATACATTATTTTCATTATAATTTTTCTGCAGTTTATTAAGATAGTTTATTGAAAGCATACTTACAGCAAATATCAAAACACATGCGCACAGCACTAGATGTTTCATTTTGTGCAATGTAAATCTTTATTGCAGAGAGTGGAGTTACCACGATCATATCGTATTTATATACTCACTTCAAAACATAAAAAATATAAGTTAAAGTAATAGATTAAAGAACGATGACTGATCATAAAAACATTGAAAATATATCATTAATAGAGATAATTTGCTATGATCATAGTATTTTAATTTTACTGTGTAGCGCAAATTAGCAAGGATAAAAAGTATTATAATAATAATAAAACTGTTGTCAAATTATAAACATTAACGTAACATGTATTGTTGCTTTATAGAAATTAAATTATGATTTAAATGAATAGAAACTTTATACAATTAAATTATTAGATATTAATAATTTATAAAAAGAAACTTACAAAGATAAAAAAATATATGACAAGATTATAAACTACAGCAATCATGTTAGGTGTGCAACCTAAACTTGAAAAAAAACTGCTTACAAATATGGATACGATCAGTCTAATAGCCAAGTACTACAAATTTAAATACAAATTAAAAATATTACAGTACAATACTAATTAAAATAAAAGATAAACAGTAAAACGTAGAATAAAACTCAATTAATCTCTCTTCAATGTTGTCAGAGGTGACGCTTTTTCTTGTACATGCGCGTTGAAAACGAATAAGTTGAATTATATAAATCATTATAAAAGGTGTACTTCAAGAACATTGTATTCGTATACTTCTAAAAATTTTTTTTAAATTAAACAAATGTATTAGATATATATCTATATAGAAAGTCTATACATTTATATAAATGTATAGAAATCTAATTGTAAAAATAACTATTAATTTAATGACCTTCTAATCTGGTGTCCTCTGAAACTTCTCGTAATAGCGTATAAATTGCTGATTTTGCGGATATCGAACGTCATGAAAAAATGGCTCCGTTAGCAACACTACACCCAGTCTCTCATTCTATTGCTCTCCTTTCTCTGTCCCCCcTCTTTCGTCTTTCTCTCTCCCTCTATCTCTCTTTTTATTCTTGTTCAAGTTTTTCTCTTTCCTGTTTCTGTTTTTCTCGCATTGTTTATTTTTTCCTTCAAAATATTTACTTTATTTTGTTTAATTAAAAGAAAAAaTATATAAATGTAATTGAATCATTGTAAAAACAATTTAAAATACAACATTATTTTATGTATCGTGTAAACGTTAGGATTAGATATAAAAAAaGTCATATTTGGCATATAATAAATCTCGATGTCTTGAGACTGATTTTGGTTAGACTAGTTAAAATGAAAAATTTATAATAATATTATAGTATAAAAATGATTCCAGGTCTTTTATGATTCCAGATTTAGTTATTTGCTAAAATATTTTAATCAAATTTTATTTAATATGAAACTTCCGACAACTTTTTTTGCAGCACCATGACATTATGCTCTTTGCAATTATGTAAACAAATAAAATTTTTATATTATATCCCCACGCTGCAATTATGCTTGAACTTATATAATTTAATAATTTCTCATTAGAGACGATATATATTTATTTAAATAGTAATATAATTTCTAACAAGAGATTCTGTTAAGCCTCGAGATTATATATATGTTTATTAAAGATAAGAAGCAGAATTTATAAAGCTTTATTTTAATTATTATATTTTAAATATCTTTTTATTCGTAAACTGCACGCATATATTATTTAAGCTTTAATTTATCAGGTTATATTTAATCAATTCTCCCTGTATAAAAAGATGATCTTTAAAAAAATCTACTTTCTTAAAAATAACGTTGTAAAAAAGTCAAATTGGTCAAGAAGAGTTATAGTATATATTATTTATTATATAAAAAGAAATTTTATACAATAATTTCTCTCACACAAAAATTTGATATGTAGTACCAATTTATAATCAAGTGTGTATAAAACCGCGTTTATATAATATTTATGATTTAATTGTAATTATTTAATAAAAAACACATAACTTTTATGAATGTATATTTGCAAGAAAATCTTGCTGTATAATAAGTATTTAATTAATGTAAGTTTGATATTTTTAGAAATTTTGTTCAGTATTTAATTAACGCATGTTTAATTGTTCAGAATAATACTTATAACAAGTAGAATAACAACAAGATTAAAAATATATAAAAATAGAACAAGAATATCTTCATTTATTAAATGTAATCTTTTGTATAATGTAATTATCTCTATAAACGTAGTACAGAATTTTTTtGTAAATATTTCTATTAAAAAATAAGTTTAACATATAAATTTTGAGTATTAATAACTTGTACGTTAACGTTTAATGCATTCTGATATTTTTAGAGATTAAGATTTTACAGATAAATTACGTAAAAAGTAAGATGAGAATTTTTTTTACATTTTAATTGAAAGAATTTTAAATTATGTTAAAAAAGAAAGATGTATTATTTGTAGATGTCATAATATAGTTATAATAAAAAATAAACATAATATTGTATATAGAGAAAGGACACATTCGTGAAATATATAATATGTATAGATGTGGGGTAATGAGATCTAGTACAGTTTTTGTTGAACTCTAGGGCTGTTAGAATTACTTTGTTAAATTCCATTTTAATGGATTGAAAGATGTTTACTAGTTAGTAATGTTTATTGTGTTTTTATAAAAGCTGAAATTCAGTTTTGTAGACAGCAAAGATTTCTACTCCCACATAACTCTTCCCCAAGGCCAGGAATACGCATAAAGTGTTTCCCCTTCGTAACCAAAAAAAaGTATATGTTCTTTACGTAATTTTCATAAGCATGTTGGATATTAATATTTTAACTTTAGTTTACCTTGAAGATTAAATGTGAATTTTAAATAATGTAATTGAATTTAATGTGTGACGTAATGTGTTTATGAATCCGACATATAAAATTATATTACGTATACGAAAAGGTCATGGGCCATTTGTATTATGACTACATCTGCGATTTTACTATCACATTTTAGACGTTGCGTAATATTTACTAGTGCAGCGAACAAATAATTAAAAAAAAaTTTTTTTTTTtttAATTATTTATTCGCTGCACTAGTAAACTCATAGAATTATTTGAAGAACATTTTTTCTAAGTAAAAATATATATTGTAAAATGTTTATAAACTTGATCATTTTGTGGTACTTATTAGTGTGCAAGATCAAGGAAAGATTATTAATTTATAATTTTCTATAAATACAAAAGTGCTTTTTATGATATTAGTTTTTTACGATTTTTTTCCTATCTCATAATCGCATTCTTTTTTTCCGTGTTCACTAAATTGAAAATTACATTCGTTCTATATACTAGATAAACCTCTTCTATAAATACATAATATAACAACTTATAGAATAATTGAAAAATTTTATGACTTTTAACAAACTTGTGTTCAAAATTTAATTAACGCATGTTTAATTGTTTACTTATAGAAAAGTGTAATAAATCAAAATACAGTTTTTATATTTGCTGCTCTTTTATAAATCAGGAAATTAAAAATAGGACGTAGAAAAATACATGTACATGTATTTCTATTTAATGTAAGTTATATTGAAAGTGTAGTATATAAATTTATTAATATTTATACAAATAATATTCAATCCGTATATTTAACTGTGTTTATTCCGTCAGCTTTTATATCTTCTTCTACTTCTTTTTATTTGGTTCTCCTGTTTCTTCTTCTTCAGTTCTTACGTTTTCTTCCTGCATACATTTTCTTTCTTCACTTACAGCTTTTATAATACATACGTATATAGAGAAACATTTATCACATTCTTGCGTAATGTCCTTCTCTGTATAAATAAAAATTTTAAAAATATGATAAAAGGATGTCATAATATATAGTTTATAATTATATGAATATGCAGTTATAAATATGTAATCTTATTTTTTtATGGATAATAGCTAATATATATTGTCCCAAAATTAGCGTCATAAGTAAGTACATGTACAAAAAAGaTTTCAAATAAACTTTCGTAACCTTATTCTTTAATAACTATAGTAATTTTtATATATTTATAATAATGATAATATAATAAGACGTAACTTACTTTCTTTtATGCATTTACGCACAATTGTGCGCAATTTTTTTtCAACATCATCAGTAACTACTACTTCATTTAATCGTGCAATAACTTCATCTTCTTTAATGTTGGTTCCTTCCATCTAATATAATTTAAAAAAAaGCATAAACGATAGAAAATATTACAATAATAATTtATTTTtATATTTTAATTAATTTTGAGAGCTATAGAAACAATAAAAGTGTCTTCTATAACATTAGTTGTTAGTATGCCGCAACTCCTGCTATCTTACAAACATGTCTTTTTTTTCAATAAATTATAAATTATGTTCATTTTATATATTCTATAAATTTCTAACTTATAGAGTGATTAATAGAACTTAACGGTTAACAAACTAGCAGTTATTGAAATTGTGTCACATTAATATCTATTGATTTATAATCAAAAAAAGATAATGGTGTTCCACCACCACTTTTGTTCCCCTATTTGTTACGACACATCAACCTTGCATTTATCACAGGTATATAAAATATGTATAGCATATATATAAACACTTACTAAATTTTGTTTTTTTAAAAAACACGCCATAAAGCAGCCATTCTTTCTCGTTTTTTCTTCATTTGCTGTTTCGGTATGTACATTAGACACTATTTCTGTCGGACCGTACAAGTCACCTAAAAATAAAATTAATCAATGACAGTAACAAACGTGTTTTTTATTTGCAAAAAGGCTAACTCAATAAAACACAAATTAAATTATGAAGTTATTAGAAAATAAAATATTTACATCAATCCAATAAAGTCAGGTGTCAATTAATTAAATCGGGTAAAATAGAATTATTTCTATACTAATTTTATTATAAATTAACTAAGTACCCTTGGATAAGAAACAACACTAGAAATATGTAATGATGTGAATGTACAATTATAACTTACTTTCATTTATACCATTTTCACTCAAGCAAGCTTCAAAATCAATCCGTTGCTTGATCTTTACTTCTTCTTGAATCTTTTGTTTTAGTTCTGATGAGTTAGACAACTAAAACTTAACAAAAAAaTAAAAATTCTTATTTATTTTATGTATTGTAATTTAAATATGTATTATTTTAATTATATTTTTTTGCAGCTAATTAAAATAGTTTATTGAAAGATTACTTACAGTGAATAACAAAACACATGCGCACAGCACTAGATGTTTCATGATGTTTGTGCAATTTATATCTTTATTGCAGAAAGTGGAATCTGTGAAATTACCACGATCACATATCGTATATATATACTTATTTGAAAACATAAAAAACGTAGATTAAAAGAAAAGGTTAAAAAAAGTTGATAGATCATACAAACATTGATTAGATAACGTTAATAAAGATAATTTGCTGTGATCATAATATCTTAATTTTACTGTAAAGCGAATTAGCAAGGATAAAAAAATAAGTATTAGAATAAAATAAATAATAAATAAATAATAAATAAAATTTTTGTCAAATTTTAAATAATAACGTAATACCTATTGTTGTTTTAGAAATTGAATCATGATTTACACGAATAGAAACTTTGTTATATTATTAACTTATAGGATATTAATAATTGTAGGATGTTAATAATTTAAAAGAACATTACAAAGATAAAAAAATGTACGACAAGAACATAAACTGCATCAAACATCGTGTGCAACTTTAATTTGAAAAAACTGTTTACAAATAGATACAATGAATCTAATAGCCAAGTACCACAAATTTAAATACAAATTAAAAATATTATAGTACAATACTAAATTAAAATAAACAATAAAGAATTGAATAAAACTCGATTAACCTCTCTTTAGCATTGTAGGTCAGAGATAACGAGAGATAAAGATTTTTTTTATATGTGTGTTGGAAACGAATTAGTAGAATTATAAAAATCATTGTAAAAGACGTACTTCAAGAACATTGCATTCATATATATCTAAAAATTTTTTAAATATTAAACAAATATATCAGTTAGATACAAATGTATACAAATCTAATTGTAAAAGTAACTAATAATTTAATAATCTCTAATCTGGTATCCGCTAAAACTAGCGTCATAAGTAAAATTTTTTTCAAGAGATTCTGTTAAATACCTCAAGTTTATATGTATATATTCAATAAAGATAAGCAGCAGTATTTATAAAGCTTTATTTTAATTATTACATTTTAAATATTTTTTTTATTCGTAAACAATACACATATATTATTTTTGCTTTAATCATGTATCAGGTTATATTTAACAAACTATCCTTGCATAAAAAAaTAATTTAAAAAAAaTTTATCTTCTTAAAAATAATTTTGTAAAAAAaGTCAAATTTGCCAAAAAAATTATAGTATATATTATTTATTATACACAAAGAAATACAATAATTTCTCTTATACAAAAATTTAATATCGTAGTACCAATTTGTATTCAAATGTGTATAAAATTGCGTTTATATAATATTTATGGTTTAATTATAATTTATTAACAAAAAAACACATAACTTTTAAGAATCTATATTTGTAAGAAAATCTTGCTGTATAATAAGTATTTAATTAATGTAAGTTTAATATTTTTGGAAATTTTGTTTGAAAATATGTAATTAACGCATGTTTAATCGTTCACAATAATACTTACAACAAGTAGAATAACACAaTAAGATCAAAAATaTATAAAAaTaGAACATGAATAtCTTtATTTATtAAACGTaTTTTatATANNNNNNNNNNNNNNNNNNNNTATATAtaTATATATATATATATATATATGTAATGTAATTGTCTTCTTAagCAGAATTTTTCGGAATTTtCCAAAGCTAAATAATGTATAATTTAGGTTTTtACGTAAaTTtCCATTACTAACAAATACGCGAATAGATTAGAGTTATGAGATCAGAGATCGCATGAGGGCATCATGTGAATATTAGAATATGATAAGTTATTAATACTTTGAATTACTGTTCAGATAAGAATTGTTGAGATAATACAACATATACGTACAATGTATTTGTCTTATGTCTGTTTTCTTTTACATTTTTTCTTATAATGTCTGTGCATATGGTTATACTCTAATAATATTCACATATTCTTATACATTAACAAATCTATAATTTATATTTTTAGATAGAAAGATAAAAATATAGAATTGTAAGAGAAATCTCACTGTTTaTGTATAGTTATGTCTTTATTATACTGTAAATATAATAATTCTCAAACAAAAGTAAAAATTAAAACAAAAAGGATATATATCTCAAATTATGTTTTtGTTACTTATTCCATTTATGTAGAACTTTAAATGGTATTATAAATAATATTATAAGAATAAAAAAATTGATAATTTAGATTTTTTTtCTTTTTTAATAAAATTAGTTTATTACACCAAAATTTATTTTTAGATTATTATTTTAATATATCAAAACAAAAaGACTGAATAAGTATATCTCTTTATTGAAAATGCTGTACATTGCAAACTTTTAtGTATCTATCGATTATATTTGATaTAACATTCATGTTTATTACAAGTTGAAGAAAGTTTCTCTTCAGCTTTTATGGTACATTCTATAAGATTAAAAGTTTTGACATTTATCTGTAAAATTTTTTGCTAAAATAGAAAAAAaCaCTTAAAAAGACACAAGAGGTAAAATACAAACATTTTTTGCGTTTGTTGTAATAAACGCAAAAATTgAAaTAGCTATAATATATTATTTGTTGATTTCATTAAGATTGGTTGAATAATTAATATTATAGAaTATTTTATTATATAAAGTAGACCTTAAATATCTCAAATAATTATTGAAATTTTTCAACAATTGACAATAAATCAATTGTTTTGGATTTTTtAATATTATTTTTAACTTAAAAAAGAATTTAATATACAAAACATTTGGAAAATAAATAACTTAGCAGTATTGTTATCAGGAAATTAAATAAAGTGTATAAAGATATTGTTAATATATTAGAGCCGACACTGATTGTTCATGTGTAATACATATATAACTTTATTATTTAATAAAATTAATAATATAGACGTTTTGGTTCTATAGTTTGGATCATCCTTAGTACAAGTTATTAACAATTATAGGATAATTACAATTCTGTAAATGGCGTATTAATTAATAACCAGTGTCGATTCCATATTGGTATTATCTTTATACATTTAATTATAATATATTTTGACTTTAAGTTTTAATGTTTGTCGTTATATTGTATAAAAGAGTACAAATCTTTTGTCCGGATAGCTACATTTAGTCAAAACTATTTTGTTAACAAAAGCATTTATTTGCTGGGGAACAGTTTATTTCTTGGGGGTGAAATGTATGAGCATTTCTTCCATGGGTCGCAAAGTGAGAGCGCCACCATACTCGATCGTGTCTATTGTTTTCACACTTTTTATTCTCCACTTTCTGAGAATAGCAGTCAATACAATTTTCTCTTCGAGTAGAGCAAATTTCTGACCTATACAATTCCGCGGTCCAGCGCTGAACGGAACGTAAGCATATGGATTTCTATGTTTCGAGTTCTCTGGAAGGAAGCGATCCGGATCGAATTTTAATGGATCCGGCCAAACCTCCGGATTTCGATGTACAAATATTATTGGTATTAAAACGTTCTCATCTTTCGAAAGGATATTATTATCTAAAATTAAAAAAaTTAATTAATTATGGACTGCATATGGATATTTTGATTAATAATACACAAAATATATAATAAAATATATTGATTATCTTTGTCGGTATAAACGTTTTTCTGAGTTAAAAATTAGACATTTATGTAAAATTATAATGTTAATTTAACACAACTTAGTGTAATTTACGTTTAGTTATAAATCTAAAAAATTATCTGTTTTTAGAGAAATTACTTTTGTTTCATTTTTAATAAATAATGAGAAAATTATTTACTAATTTTTATAAGTACTAACTTAAAAAAaGTCAAAAACATTATTACATTTAATAAATTTACACATTTACAATACAAATTCTTTAAGATTTTCTTCTTAATTGGCAAGTAAAATAACTTACCCAATTTCACGTCTTCTGTTAGAACCCTCGTGATTGTAGGTACACTCGGAAATATTCGGAGCGTCTCTTTTATAACTCTATCGAGATACTTTAATTGCGACAGTTCCTTTACACTGGCTGGTATCTCTGAATTTCCAAAAACCTTTTCGAGTTCTTCGTGAACTTTTTCTTGATGCTCGAAATTATTGCCCAAAAGAAAGAGTGTCCAGCTTATTGCAGACGTAGTTGTGTCGTGTCCCTATTATTTTCATATTATTTTACAGGTACTTGTTATATACATTATCGAATGATATTCTAATAAAAGAAAATTTTGTATTAAAGAAGTTGGAGAATTTTAATAGTAATTCTGAATATTTCACCTCAAACATAAACGTGTCCACTTGCGCTTTCAGCTCATCATCGGTCAGAGGAGCATCGTCTTTCTCATTCTGATCTAATAATAAATCTAGAAACGCTTTTCTCTTCCATTTACCTAATATACAAAATTTTTtCAAATAAGAAAAAGGAAaGAGATATACGTAAAACGTACGTTGTATATTTATAATTTACAATAATACCTATGTCAGATTCATTGTCCTCATCTTCAGGTTTCGTTTTATTGCCATTTTGTAATTGCCGTTCAACCATTTTCTTTCTTATCACCTAGAATTTATCATGTTtATTGAAAATGTAAAATTTTTAATTATGTGTAAAAAATGAAAATTTCTACCTCTTTCGTAAATCCATGCAATGTATCAAGCGCTAATTTATATTGCTTTCCTGTGGACGTTAAATAGTATAACCAGTTAATCCAAAACCACGGACGATAGAGTCGTTTTGCCAATAATTCGGCTATTCTGAAAGTATAATGTTAAAaTATTAGCGTTTATAACTTAaTAAATTGTATATTACATATATATATATATATACATATATACATATATTTTtGACATTTTACTCTCTCTCTCTCTCTCTTtCTATATATATATATATATATATATAATAAaTAATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNtATaTATATATAAAaTTAAAGTTCAAAATtAaTTTTtAACATTATTAAGTAATTAAATATTtGTTATTTTATTAACAATAGTAATATAACAATTTTGAACCAACTCATGTATTGTTGATGAATATTTGGATACGATTTCTTGACAACGAATGTCCACACCCATTGCCGTTTCTGCAAAGTAATAATTGATATTTTTAAAACCTTTAACACCTAGTTTATAATATTATATATATATAAACTTAATATTTATTAGTACTACATATATATTTATTAGTAATTAATATTTATTAGTACTACATATATAAACTAAATATGTATACAATAATACAATAATATTACAACAAGATCTGTTTTATTACTAAAATAAGATAATCGGACTAAATAAAAAATTGCTCATAAGAATGCAAATTTGCACGAATCACTATAATTAATTACAATATTTCTGATATCATTTGGCTACTAATTTGATAACATAATAAGAATCTTTGTTTTTATAGCGAAATAATTTGCAAATTTAGCAAAATTGATACTAATAAACTTAATGTTTATGTTTATATCTTTTACTTTCCATAAAATAACTAATAACATTAGTTGCAGTATATACATAACGTATTATATTAATAAATATATTTTTACCAAAAATATTATAATTATATGTTATTGTATTGTAAATTAAAAAAaTAATATATTACCGCAGATAATATCAAGAGTAGCATTGAGAATAAAAGGAAAAATATCAATGGCCTTTCCGGGATCTGTTTCTATTTTTCTTTCGAGACACTTTATTAAGATTTCTGCTTTCTCAGATAGAAGCACAGCAAATTCATCTAATATACTAAAATGAAATGTTGGTCCAATGAGTCTTCTATCATGGAACCATTGTTTACCTAAAACAGCGTTAAAGTATGATATATTAATGTTGTAAAATATCACAAATGTGAAAAGACTAAAAAGAGCTACAAAATTAGATAAAACAATCAAAAAAAGAATAAAAGCCCTGAAAGCATAAGGAGATGTATGTACTTCTCTCTAAATTCTTTGGATTGAAATCTTACTTTAAAACAGTGAAAATTTAACCATTTTTGACAATATATTGTTACATTAGAGTTCAAATACATATATAGTACATATATGTATTTGACAGAAAATAAAACTGTCTTAAGTTAGCGTTTTTTTATAGCTTGTCTAATATTTCATAAGTGACTGTACTTATTAAATCTAAGTAAATAAGCTGCAATGTATTTTTAGTAAAATTCTATATTTATAAGGAATGTATATAAACATATAATAGATAACTAATATGATTTTATTACATGTTCACCTGTAGATAATAAAAGTCCGTTGCCTAACCAGGATTTCAGTAGAAAATAAGGAAACCCTTTTGTGATATTTACGGTGCTGGGTAAAATAAGCTATAAATAAAGAGATATAATCTAATGATATTTAAAAAAAAGGTGTAACATATTTTTCAATGATATTATGCATTTTATGATGATTTGGTGATTTTGTGATACAACATAATTTGTCAGTTACTAACATTAAAAGGATTTATTATGATTACTAATACCATTTATCAAAATGTTTTACTGAATTTTACCTGTAAACATATTTTATTACAATTTCTATTTAGTAGTAATAGTTTTCCGTGAAATTAAATCGGATTTGCTAAAGATAAATTATTGTATTTCAGAAAAAGTTTCAATTTTTTCAATCAAATTCACACAGCAAAACTTTCAGTATTGTCTATCCTTTCTTTACTAATGAAACATACAATTTACTGAATAGTTATACAATAACAAAATTTGATTATTATGTATTATATATTATACATACATAATATCAGTATCGATAAAAAAACCTCTTGTTTAATAATAAAATGATACTGTATTTTTGCATTATTTTGAATTATGCAACAATTAAGTTTTTTGTAAGAAAAGTAAATTGAGAGTCTGATAAAATAAACTAAAATCAAAATAATTAGTAATGATATATTTTCCTTGTCTTTTCTTTTCACATAAGTCATTTATTTTCTAAAATACTTTTAAGTTAATGTATATGAGTATTTTTAAAAACCTTTTACATCGATGTAAAACGTTTTTCTAGATTTTATAAATACATTATGAAAAATCAAGAGAAAAGAATATAAGTTTCAACACGTTACAAGCACTTAAAATGATCTAATATTAATGATATATTCACTGTTATTTATAAACTTATGTCATTTGCAAAAAATAATTGTTAAAATATTATTTTTGCATTTAAAGACTTTGTTTAATAACTGCTTTCATATAACAATTAAGTTATGGATACATGAATTATAGGTTTTTAATTCTTTAATTATCTAAGTAAATCAAGTTTCTGTCAGTGTCAATAAAGAGTAATATTTACTTTTCAAGAAATAAGAAAGTGTTTTTTTAGAAGTTCTATGTTTTTATTGGCTACTTTCCTCTAATTACTTATAACAAAAAAAAaTAAAAAaTAAAAAaTGACGTTTTTTTGTTAACAAATAGTATTTACCTCTAAATATTCTGGTTTATACACGACTATACCAGGATTGCCAAACATCCACATTATAAATATTCCTTGCTTATACGTCTTTTCTATATACTTTAAATAGAATTTTGTGCGTTCTGTTAATTAAAAATTATTATATAAATTTAAATAGTACACTTTTTATTTTAAGCAGTGTGCGAATACACAAATAACACTTGTAGATTAAGAAAATTTTAAATTTtAAGTTTTTtACCATGaTCCGGTCGATTCATTAACGCAAATGCTGAACCAAAAGGAAATCTGTCGACTTGGGGAATGTTTTTAAGTCTTTGTCGTGTAACATATTGATAATACACTAGCGACAGAACTCGGGAAATCACAATAATGCAAAGAGTGCATAATGCTAAAGAGATTAAATCCATTCTCGCAACCTGCGAAAACTTCAAATAATTTAAGTTACCAAATAACAAGTACATTAATATTATACCAAAATAACTGCACTGTATTCACCGTTACTGTCTTTTCAATACTGATTTGAAGTGTTTGTCAAAAATACGTTCAATTGCGATAAAGTCGATATCAGAGAATATATTCCGTGTAAATAAAACTTATCAATGCAATTGAGTAGTTGTTGACAAAAAATGAAATGCTTTTATCGGTTATCTTAAGAAATAGTTTATTGATAGCTTTACAAATAAAATTTAGCAAATGTAGTTTATGTAATATTTATTTGCTACGTTTTACTCAAATTGTATCATTCTTTTATTGAATTTACTATTTTACATAATGCTTAGCAAGTATGATCTTTCGATACTTACAGTTTGTTACTTTAGAAGACTCCGTAGTTCTACAATACTCGAATATCTCATCAGCACTTTTGCCATTCGATTTAATATTACAGCTTTGATGTTTATAATATGATATTTATAGTAATTTACGTTTTATGATTTGCATAAATGTAAATTTTACTTTGTTTCAATATTAAATGCTGTTTAATAGGTAATAGATTATAATTTTTGTAAAAAAGAGATTATATTAAAGATTATATTAAAAGATAATATAAAAaTTTTAAGAAAGGTTATAAACCGTATTATCTTCTTTCTTTGATTTAAAATTCAATTGTGAAATAAAACTTCAACATATGCGCGGTATTTTGATCTTTCACATCTCTTCTTTATTTTAAGCAAATTTTGCATTGATAAGTATTCACGTAATAGTTACATACCATATACTGAACCAAACATTTATAATATTATTATTTGATTTTTCTAGTAGCTTTTACGTTTGAAAAATGTTGCACTGTGAACAGTACTTTTACAACTGACGAGATAGAATGGAGACTTACATTTAAAGATATGCCTCTAATTTTTCAATGACTTGCAATTTATACGTCAGTGTGAAAAAAGCCTTTATTTCATTTGCATAAGATATTTATACGTAAATGAGATACTGTTTTTTATACTTACATAATTGCAAATCACATTTCAAAAGTAAAAATAAATTTCAAATTTAAAGAAAAGAAAAGTATTCGGACAAAGCAATTTGATCCTTATTGAAGACCTTGATTAGCTGTGCAAATATTAATTTTCTAAAAAaTAAGTCTTTCCGGTGTTTAATGCGTTCAGAAAATGTCATCACAGGATGCCTTATGTAATTATTCAGGAATAATAAATATTTTAATGCACCTTTGATCATAGATGTATTACCTACTGGAAATATCCGTGGCTGTAAGTTCAACTTGTAGTTTTGTGTGGATAGAGGCGCCAGCGCGTATTCCATCTAAAATACCGGCATGTCCATTTTAAAGCTTCTTTCTGATAAAACAATTTGTGCAGCATTCGATAAAAAAGTTCTACTTAGTGAGACTAATAGATTTCAAGACTAAAGTTTATTGTATACCTTATGCAAATAACGTGGAATTCGTGGAACGTACTTCAACAATGTTACATGTATTATATACCTTATGCGAATAACGTAGGATTAAGAATATAACATACTTCGATAATGTTGAAAATAATATTACAAAAATCTATAATTTTGTATGTATCTATGTTACAAATTTATAATGTAAACAATAAAAAGATATTTTTACAAAAaCATTTTTTTTAATTTTtATTtATTAAAACGCTAACAAAATATATGCATTTATTTGATATTATTTGTTAGCAAGCTAAAAAGCAGATAAACGCGAAAAAaTAAAATAaTTAAACGTTAGAATTAATAAAAaTGTATCCAAAAAGTTTTATGTAACTATGTAAATTAACTAATTAAGCTTCAAAGACGTAAAGTTCTAACATTTTATAGCTTATTGTTGGGTTTCCTACCTCTTTTCTAGATCTTTAAAGAACTCCTGTGAAGTGTTAATGCTGATTTATTCTATTCGATAATCAGCTATTTGATTGAAACGCAGGAAATTTATTTTATTGTTTCTTTTAATTTTAGATATTTGCAAAAAGAATTATAAACACAAAGACAAAAAAAAaGACGAACAATCAATTTTATTCAATTATTATAGAAAATATTGATGGGCAATAAACATTAAAGTTCTTAATGTTTAATGTTCAAACAGAAGCAATTAAAAAAAAAaaTTTGTATTTtAGTAATATAGAATTTTTTtAAATTATATGTATAATGCAATTAATACAAAGGAATGTTTCGTGATTAACTTTCATACGTTTTTGGATGTCGCTGTGTTAATAGTAATATATGTGTTAAACTTCATATATGTTTGTTTAATAGCGTTCATATATTTCGAGAATTTGTTACATTATATAAACATAGACATTTTGTTTTtATGCTAATAATTCTAATTTAATATACCTAAAGTATAGAGCTATAGTACTTCTAGGCATGCAGTATTCCATTGTTATTTGGTAAAACGTGCTTGCGCAATAAACACACTTATATTCGTTGTCATGCGCATTTCGTTATACCTCGACATACTCATTCGAATCATCTTTCAGACAGCATACTGTATTCACTGACGCTTATACTTTCTCGCTATCTCTTTCACACAATTCGTTTGCTTTTATAAGTTCACACTCTTAGATATTATTGGATATTCTGAAATAACATTAAAAAAGAATAATTGTCAGACTTTCATTATGTTACAGCGTTATTTCGGAGATCGAAACTAAACTTTAGATTGCAATATAGTAAACAATATTACTGATAACATTCAAAATCCGCAGAGTTCCAATGAGATTAAATTTGAGATATGTCTAAATATAAAGGAAGCATAATTTTTACAAAAATTTTTAACGTCAATAATATTAAAATCAAAATGTGTTTAATATTTTTATTAGTTAATATATAAAATTAAAATATATGTAAAATAAATTATAATTTTGGCAATATATTATATACATTTTTATAAATATTTATCTGTAATCGTGCTGTAAATTTATATCACGAGTTTTGTTTAAATTGTATTAATTAAATTTTTTtGTTGTTTAGAAATAACTACTCTTTTTAATTAACTAGTACCTACTTGGAATGTTGCCAATCTGTATTCACATAAGTCCCCTAAATAAAAATACTCAAATTAAATAAATTTAATATAAAAAaGTATTTAAaTTTTGTTATGTATATGTATAAAATTTCTAACATAAATTTTATTTAAAGTAGTCATCATGTAAAAAaTAAAGAACTATATTTTTATGATTTTATCTAAAAATTATTAATTATTTAATGCTATCTAAATGTAGTAATTTCTATGCATTAATGTCTTTGTCTACGCTTATCACATTAAATATGTGAAAGCAGGTACATATTTAGCATGGAAAAATTTGATTTATTACCTAAATCGATATATATTGAATAATAATTTTAGGAATTTTtAGGAATAAATAATATAATTTTACGCCAATAAATATTAGTGCAATTTGCAGATTTATCCAGTCCCGAAATCGCTTATTGGTAACATTCTTCTTCGATTTGATTCTTTTTATTCACTATTATCTTCCGTTTGATCACGCACGACGTAATTAAATTCTCGCAGTGGATTTACGAATGACAAAATAGTTTACTCGATTCTTGCACCGATTATCACAAGGTATCAAAAGACAAAGGATCTTGACGCTTACGTATCCTTTGTAGTCGTAGACTTTATGCGATAAATGTCTTCATTTTATACGGGTAATGCGAATGCTGAGCGTGACAAAAGAAGTAAATTCAGACAGAAATTACAACCGAAGAGACACTTTCCGAAAGACTTCCTTCTGTAAAATCAAGTAAAAGATTTCGCTCTCGCTTCTAATGTCTAGCAAAGTCGAGGCATGTGTGTTCCTCGAGGCGTGTGATTCGATAACTCGAGGTAAAAGTGTTCGCCACGTTCTGCGAGAGAATAAAAGCCAAATAGTATGCGTTTCGATCGCATGCGCCAGTCCATTGATCACGAAATATGTTAAATTCACGTCAAATAAATATACAAATACGAGTTACGGAAATTCCGGATGGCACGGAAACATATTACGATATTACGAATAGTCCCTTTTATTATTGTCCAATATAGATGCACAATTTATGATAGATGTCACACATTGCTTTGCATTATAATTTTATATGACATTAACATATTACGCGTACGGGATTTACCGTAATTAACGTAAAATCATGATAACGGTTTTGCATTTAAACGTTAAATCCATTACTTTTTTGCAGCTGATAAATAACGTTGTTTATTTATTTAAATAAAGGAAGATATAAAATTATATAAAATTTGTGTTTAAGGTAAAATGTTCATGTAATTTTTAATTCAATAATATTGATAATGGTAATATTGATTAGTGTTTTTTTATTTGCAACTCTACATTCTCTTTAATGCTAGGGGAAAATTGCTAGATGCGTACCCGTCTCCTAAAGCGTATTTATTCAATATTTTATATTTTTACTTTATATAAGCAACATTTATTGATAAAAAGAAAAAaTAAATAAAAAATAAGTAATTTTGAAAAAAATTAAACAAGTTTTATTTTGTTTTGTGCATGCTGTCATTAATCTTTAATTACTTTAATAATAAATTCAATATTTTCAAAAACGATACGATTTAAGAGACCACAGGTACAATTTAAGCAACCAATTTTCTAAATCACACTTTTTACAGCATCTTACAGAAAAGCTTGTAACAAATTAATTTGTTATTATTGAAAGATTTAACATGTAAAAGATGACTAAAACATCGAGCTCCAATTTCAAACTTTAATTTGCATTCAAACAGTATCAAATGCAAAATATAATAAAAAATAGCTTAAGTGATACGCATTTGGCAACTCTTCTCTAAATCCAGAGCACTCATTAAAGGTGATATAGATGATTAAATCATATATTGCAATGGATTATTAATACGACGAATGAACGTATACTGTCTTGCGTATGTTTATTTGTATTTTGTTGGACCAAATGTACAGAGTCGTAATACAAAATCTGTTCTCCGACAGGCGCTAGCTTCGAGTGTTTCGCAGACATTCGTTCGAATGGGACTGATAAAATATCAACAACCAAGTTGTTCATAAACGTAAAAAaGAATGGCATAGGGAACTTATGTGACTATTAATACTAGTAAATTATATTTCACTTCATCGTACTTATACGATCTTGGTACACTTTTCATTTACGGTATGTAAAGAAGAAAACGTAAAGATAAATAATGATCTTCGGCTATCGATAAATGCATGCTATCGTGCGCGTGTGCACATTTACAATTTAAACAGTTTTCACTATTTGTCCATACTTTTGCTGTGAATCGAAATAAAAACGTCTTCCGTGTGAAACTAAGTAAAATCAATTGTGAAGTTAAGTAAAAAAATATGTTGAAAATCCTATATGTCATTGGATAGATAACTTGTCTCTCTCATACAGCCAGAAACTGATTGGTAGTATGACAATCGTTATCCGTGGCAGTTAAGTGATGGCAGTAAATTTCGAGACGAAACTCTAAGAGATACGCTTCGATCGTATGGCCGTTTGAACGTTTAGCGGCCAGAAGCTAAGTCTACATAAATTCTACGATTGGTACTTTCTCGCGAGGCGCACGCTAGGCGGCAAAATCGCATTGAAATCGTAAAGGACGACAGCAAAGCACGCCGAGAGACATTCGTTCGTCTTCTAAGTAAACGTATACGTTTAAAAGAAACGGTTTAACATAAGTGTCAGTGAAACAAGGAAACGGAATAAATACATATAAATACTGGCAGTGGAAGATGCGATGCAGTTATCCAGGGGTAAAATAGATACGCATAAATAGATGTAAGGGTAGGTACGTAGTACGTCATACATTATAAGGGCTTAAGTAGTACGAACGAATTACGCTCTTTGATTAAACTAATAGCAAATTAGCTTAGATATATAAATAATGCGCTTATACAAAAATAATTACGCGGTTTTCGTATCGGTGAACTCCTTGTTTCGGATTACCGACGATTTCATCGACCTATACAATTATATCCGTTTCGCAATCGGCTGACCGAACGTTAATATGCGCGTCCCTCAATAATTCGTTTTCCTATTATCGTACGTTGCGTCGATTCGCACGCAAGTTTTCCGTTGCTTCGTGCAACAGCCCCACGGGCTGCAACTTACATCTCGAAACGTAACATTAGGCCGTAAAGTGAAAAATTTTCGAAGCGCGCTCTCCAAAACTATATAACTCGCGACGCAGTCCGTCCCGGCGTACTCGATCGCGCGGTGCGATTTCTTGGCTTTTTCAAAAATAAAGCTACACTCCCACTGCTGCTGTCGGTGAGGTGAGGTAAGAAGACGTTGACGGCTTACTTTCAATTAAGATCCTTCTATTCTCCTTAAAATATATTTTACATTTAGTTAGACACTTACCTGTGATCTATTCACATAATTGTGACTCTATATGTCGATTCTTTAATAGCATATTTGCTTGTCCCCTCTGATTATCGTGTTTGTTACGATTTACAAGCGGCCTATTCATTACTAGCTAAAGATTGTGCAGTTAAAGTGGTAGTTGGAACGCTAAATTGGCAGCATTGCAACTGAACTGATGAAAAAGGCAAGAAACACACCGCCCCGTTTCCCGTTCTGTTTGCCTTTCGTTCCGTTCGGGTTTATTGGCTACGACGACGTGTGTATTGTAGCCAAGCGAAGTGTATAGAAACCAAACAATCTGTAGCGAAAAAGTATTGCAGCCATTCGCGCCATTCTCACAAACATCTCTCTCGCTATTTTTCACGTATTTGTAGATCTTCTCTTGCAAAAATTCAAAGAGACCATTGCTCAGTGGGTAGAAATAGCTATGCGATCGAAGATTCGCGTTTAGTGTAAAAATTCGCTGGGGAAAAGATAGACCTAACGTGGATCTAGGTTTCGCGATCAATTATCCACAAACTTTGACCAAGTGAAATTACGATTGTCATTAATTTTCTTTGTTACGTAATTATAAATACGAAAACAATTTCCGAGGAATTTAATTCGACACGGGGCAGACGTTAATTCTATAATTGCTTTACTCTGCGAGTAGTTTCGAGTAAAACGTTAATTACATTTTCTAAATATTTTTTTAAAATTTTCTAAACGTTTCCATTGTAATAAGGGAGAATCAACACGTTACCGAATAATAATTTTCGAACGATAGGCAGTGAATTACATTGAGATGGTCGCGTTGAAGGCTCAACGGAGATTACGACCGCCACCGGCGGAAACGTATTAAACAAAAAGCGGCGCGTATATATCCTATAAGAAGATTACGGAAGCCTGTTTGCACGCAGCCGCGAATCCCCTATTACCCAGTTAGGTCCATTCCGCGCTAAATCAACGGCGTAATCGTACGCACTCGTGCGTAACGTTACGAACACGCAAGCGCCCGCGTGCGCGGTCCGCGATCGCAAATATACGGACACATTGTCCGCGCGCGCTCGCGCTCACCCTTCCTTCCGCCCGCGTTCTCGTCGTTATATACCTATATCGGGTCATTATATATACGAATAATACCTAGTATACGTTTAACTGCTTCGATATCGATAGTCCGTAGCTATATATTACGTACAATATACTCTTGCGTCTTCTTTTTTTTtCTCTCGCTCTCTTTCTCGCTTTCTCCTTTTTCTCTTTTTAATAATACATATCACACTGAGCCGGCTATGTGTGTGTCCATCTAGTTTTGGCCTGCACTTCCCCACGCACTCTCTCTCTCGTCCACGTGTGTCTCGGCGAAGGTGGTCTCCGCATAGGGATGCCGAGGGCACGTCGGTGGCAGTGCTCGCCCTCGCCCTCGCCGTCCCGCTGCGCTTCCTTCCTTCGTCATCTCCGAGGACACGTGGAAGTACGCGAGGGGGTGCTGCTTCGGATCCGGGGGTTTCTTCTCGGTCTCGTTTCACGTCTCGACGCACGCCGACGAGACTCGGGCCGCGATGCGTCGACTGGCTAGTAACATTTGCGGGTACACGTGCACTTACGCACCAGGTCAACGTCCTTGGTGTACCGCATGCCGTCCGTGCAAATTAGTCGGACCTGAAATTAATACACAATTGTTTATATGACCTCATATACGATTGTAATCGGCAGATAACGGCGGGAAGGGATCAGTCGCCGGTCGGAACTTAATGAACATAATTGCGGTAATTGACGCGGTTGCTTCGAGCGATTCATGCGCGATCGATCACTTTGGAAGATGAAACAGTTCATCTTGCATCGTCCAGTCGTCGTGAATGACGCTGTATTTAACGCCAATTAACAGGAACAAGAGCGATGCAGGCTTTAATGTTCATCCCCGTGTGCAACCGGGAAAATGGGAGCAGAGGCTCTCGTAACATGTAAATGTTGATGCGATATTAGTTTACTCCGAAATTTGATAGACTCGGACAATTGAAAATTATACAATAGAATCAACGCATTGTTCCGCGGAAAACCGGATCATTCGCGAGTCCTAATCGGTACGCAAATATATCTTATGTACCTTGCGCCGCTTAGTCTTCCGCGGTAAACAGCAGGAATTGCCGCAACTTCCCCAACATTTAGCAAGCTTCACGGGTCGTCGACTTCGACATCCATTCTCGCTGTAGTACTCCCTGGTATGCTCCTTGCGACATGTCGgTGCTGCGACATTGATGTTAATCTTTTTACTGATTGCGATCAAGCGAGAAGCGTTATGAATTAAGTACATAATAAtaAAAAAAAATATATATTTTGAAAAGAATGCAATACCTTACATTATTTTATAATAAATCTATATTCGCGGCATAACATATCTTCATATTTGAGCATTCGATAATATTGATGGATTTACCTTTCTCGCAGTATCGTCCTTGCCAGCCGGTTTGACAGCGACAAGAATAGCCGTTGCCGTACGGCGACGGTATGCATTGGGATCCCTTTTTGCATTCATGTCCAATACATGCGTGCGAAGGCACCAATCCGGATACCGACATAATGATGTCTAAAATTAATGTATATTTTTTtACCAAAAATGTATTATATAAATTTGGAATTAATTTAAAATAGAACAATGTTTTTCGACTTTTTAATCAAATTTAACTTGCAATTTCTCGTATTATACACAATACAATTTAATATATTTCATAAATAAATTGTTAAGTTATTGTGTTGTTTGATTATTAATTTTAATTAATTGAATAGTTGCATTAACCCTTAAACACACAGATCTTTAAAATACGTAAATACATTTTCTAGTCTGAGAGACTTTTTCAACTTTGAGAAACTATAACTTTGGTTTCAATAAATATTTTTCAACATTTCTTTTTAAATGGAAGTTCAGAATTTTGGAAATGTGACTGTGCAAACGACATTAGCGAAAAATGTTTTATTGAGAACTTATAAAGGAAAAACCATTAGACAAAAATAAAAAATTATtCAAAAATCTACTTTTCTTCACAAAATCGTATCTTCGCAACAAAAAACTTCTTAAGAATTTTAAAATACAGTGTTTTAAAGCTAAAGCGTCATACTTTCAAAAAAAaTTATTGGAAGTTACAAAAGATTTCTGCAATGTTAATACAAACTTGCAGCACCGTTGAAATGTCCGTAATTTTAAATTTGAAAATCATTATGACATTTCGGACTATTCGAGATCGACTGCTAATTTTACTGGCGGACGAAACGAAACGCAATGCCAGTAATTTTCACTTCTGCCAACTGCATTATTTTTAGTTATAACCAAACTTATTTTCGAACAGAGAATTTCTAACTTTAGACAGAGTATCTGCGAGTAATATACGCGAACGGACTTGTTCGAACGTGTTTCGTAAACTGTTTTTTTtATATAAGATTACTCATAAACAAGTTTCACTCATACATAATGTTAGTCTCACACACCCCAACAAAACCTTGCTGCCGTGCCATTCGAATTCTAATTGATCAAAAAGTTAATTAACTATATTAATCAAAAGAGATTTCAACATTTTTCAAACCTCCTATCTCATTCCGTCTTCACACAGCAAGCGTTCGAAACTTCATATGGGACCTCTCAGACTCACTTGTGTATTTAAGGGTTAATTAAAGTAATCGAGTTAGTGTTAAAATAATTAGTTAAGTATATAAGACTTTTTAAAAAATCCTTTCTAATGTTATTCGTGGATAGTTTTAAGTACTTTTAGAAATTAAAACTCAACTTCAAGTAAACGATTAACTCAATAAGTTAACATTGCATGAATTAGCAGTTATAAATATTAACATACCTGAATGTTCGCGAGGCATATGCTCTTGTGGCATGGACTCCTCGTTACTGCCACTATTGTTAATTCCCTCAGCCTCAACAACATCTCTCGCTTCGTCGGCCTCCTCGTCGCTAGTAGCACATCCGGGAGTAACGCGATGCATCTTTGCGGCGTTGCTGAAGTCTACCAACTTATGATTGATCCACATCTCGGAGATGCAGCCTGAGATAAAGCAAAGAAACTTTTAATGGATCTGGTGAGAGAGAAACTTTTGCTCTATCCTATATAAAGAGTGGCGGCATGGGAGTGTGTACCGAACGTTACGATGCAATTGAGTAAGGCGCAAGTGACGCGGGCACGCATTTGAGCCTACATAAATTCTTGTAAGACGCTACGCGCAACTTCACTGATTGACGTCGATGATGTACACTTTCACTATTAAAATGTCTCTCTTATCTTATGACGCAAAAAATCCAAATACGATTATAATCCAAATTATGCTGCATGTGCAGTCCGATTACGAATTTTCGTGTGTCGCATTGTTGCGAAACTTTCCGAATCTAATTTCTCTCGGTTACATACGATGCCACATATTATTTCATACACTATATGCAAACGTAGTAAATCAGTATTGCGCCGGGGGACATCAAAAATGTAACCGAATATTAAATGAGGTCTCCGCAAGTTGCAAATTTGCGGCTGATATTCCGAGTTTGCGACAACTATCGTTTCCCAGAGGAACCGCAGAGTATCGGTGTTAGAACTAGCAGTGGTGGAGAGCACAAATCATTCGTGAAATCTTTGAAATATTCTCAACCGAACGGATTCATTATATTATTTTATGATAGTTTTTTTACAATTAGCTAAAAGTAATTTGATAATTACATGGTAAAAACTAGTATTTAAAATAACTAATTTAAAGGTAAAATCGAATGTAATTTGTCTCTCTAAGCTGCAATGTGACAAGAACACGTTTTCATAAAATTCACGTTTCTTTGCGATTTTATTAATACTATTCTATTTTCATAATCGCGACACTTCTCTCTGTCGATGACTTATTAGAGCTCTAAAGATAATACAGTGCCAATTAATCTTAACCATATTTCTCGCGAGAGTGTCGTGAGAGAAACTTACCTTGGAAGCTCGTAATGTTTCTAAGGTGAAACTCGGTAAATGCGACTTTAGCAACTTCCGGCGCTACGCCACCGACAAACATCGGCGTGACAAGCTTGAGATACTCCTTCGGACCCTCGTTGATGATGCTCCTGGCGGGGCCCCGGTCGACCCTCATTGTAAAATTTTTCTTGATCGCCAGAAGCTCCGCCATGTGAGGCTTCCCGTCGGTCACCATCTCGTAGCTGTACATCGTCGAGGTAGGATAATTACCCACGTCATACGAAACCCTGACCCGCCCATTAAAGAGCTCGACGGCGATGTGCCCGTCGTGTTGCCCGTTATAAAAGAGAACCCCGTTTTCCTGCGTGGTCGTGAATATGATGGTCACGTTCGCCTCGGGCCTCGTGCGTAGCGATTCCAGCTCGACCAGCGAGCTATTGTCCACGAAGCTCAGACTCGTCAGGTACTCGCATCTTTTTCCTtAAATGATAAATGTCGTATTAAATTTGTCAAGAGGTAACAGAAAATTTTTAAGCTTTAAAATAAAATTGGTAAGTCTTTGATTAATTATTAAAAATATTTAACAGAAGACAATAATTTTGTGTAAGATTGTATCTTTTACTTACCGGTATAGCCGGGATGGCACTGGCAAAGATAGTCCGCGGCGGAGGGAGCGGGTTGGAAGCAGGCACCGTACTGACAGTCGTGGTGGGCACACGGACTTGTCTGTGGATACAGCATGGCTGTCGAGGGTGCAGCCTCGCAGTATCTCCCTGTATATTCCGCCGCGCACTTACATTCATAATTGTTTATGCCGTCAATGCAAGTAGCACCGTTCTGTGAAACAAATAGATTACAATTTGCAAAAAAGTAGTTTAATGAAACCTTCGTGTGTGATATGTTTTTCACTTTTTTCACTTTTTTTAGATTCTTATTAAAAATTTTTTGAAATCTTTTTGATAAAAAAATCAAATATCAGCATTATACTGCAAAGATCAAATTATAAAACTCGTAAATTCTGCTTCGTTACTCTTATCAATCTTAATTAAGATCTAAATTAAAAATAAGGGATTTCTTGAAATTATTACATATGAAATAAGATATTATAAAAATAATTTTGATGTCGATGCATTTCTAATATAGTCTAATTAATGTCAGCCAGTAAGTTTACGGATAAGATAGGAACGCGCACAAACTGTGGATGCAACTAACTACTAGCAGAGGGTTACAAATCATCGGGCGGTCCGCCAGTTTCACATGCCTGGTCTAGAGTCTCAAACTAAAGGCCATGTATTCTGGGGCTTAAGTCACATATGTGCAATAATATATCCCCCCCTGCGAGTTACACGTGCTAATCTTATCAATGGTTAGTCGGGAATCCTGCTCGAACCATTGGAAACGAGATTCGGCATGTAACGTTCAACGTTATTACGCTATAAAACGTTTAAATGTGTCACTCATAATTATAGCAATTAGGACGACTGAAAATGTAGCGCAATAAATCTTTGAATTGACCGACATGTAAAGTGTATTGTGCAAAATATCAATATCAATATCAATTTTATAACTACGTATAGAATATGCTGGATATATGGAAATGGAAGTTTCATAGGAAGACAGCCTCTGTAGGTCAATTCCGCGCCATTCATGGAAGCTTAGAAAGCTTGGAACGTGATATACTATCGCTGGCTTTAGAGCCAGCACCACAAAGCCGAAAACTCCACACGAGCTTTCTGTACTTCGCGCAAACACTCAAATGAAATTTGGCCAGCGCGCAGCGTTATAATACCGCGAAGAAAAATCTCAGCGTAAAATTTCATACGCCAACTTTGCTTCTGGGTCGTAGCTCTTCGCGACTAAAGTTTCTTCCTCTCGGAAGATCATATCTGCCTGGGTTGAGGGTTCTATTTAAGAGTCGATAGTCAAATAAAAGTTTGGCTCTCATGCAAGTCAAGTTACGTCGCTGAGTTTGAGTTTTCAGTTGATACTGTACCGAATTAAATCGATACTACATTAAGTGATTCAACCAGGAAATACTTCCTCAAATGAAATGCAAAGAGACATATCCGCGCGTTGAACCCGCCAATGAGTGGAACGCATACACGATTCAAAAGTAAGATTTAAAAATATGTTATCAAAGTTAGAATATTTCAAAACGGCGATACGCGCTATTATTACAATTCTGCTAGAAACGTAAAGGGGAGCTGTTAATGCGGCAGCTAGAAATTAATTGCGATTGTTGCAACCGCGAGCGATACGAGAAAATAAATTTCTATGATATGATGTAAATGAAACAGATATCATCGACCTCGTGTAGATAGGTGCACCCGTGCACGCGACTTCTGCAGTAACGTAATTACTTATTTTAATGAATTTTACACTCAGCAGCATTACTGCAGATGTTGCGTATTTATAAATGCTAGCGCATAGAATTTTCTAAATATATATTGTGAAAATCCTTATCGCATTGCAGAGAATTTATTATTATAAAATCTAAAAGTATTTAATTAATATTGCTGTCTCACCATCACGGGGAGAAAAATAATGTATCAAAATATTACTGAAAAATAAAATTGCTTAATATTTCATAACAATTATCAAACATTGGCAGAAATATATCGGCAAATGTAAAATTTATTTCGCCGACTTTTGTCACGCGCCTTATTTTAAATTTTAAAGCAAAAAAATTAATAATTATTAATTCATGAAATTACGTACTTTTTGCCAATCATTCGTTGTACACGAATAAAGCATAGAACCCGTAACAATCGATATGTTACTGTGACAAAGCACGTGTTACTACCTATGTTTGCTATGTACGGTAGTTTCGTTACACGAGAAGACAAGGCACATTACGCCTGGCGCAACACAAGACGTGATTCGCTCTGAAGAAACAAATAAGCGACAATCGATCGTGCCCGCGATCGATAGAATAGTTAACGAGGATGGTGGCACACATACCTGGCACATATGATCGACACAGTCATCCAAGTTTGTGGAACAATTGAGGCCGGTGAAGCCGACTGGGCATTCGCAGCTGTAGTGGGTCTTGTGGTCGACGCATCGGCCTCCATTCTCGCAGGGGTCGTGACCTTTTGTGCAAAAGGGTATCTTCTCCTCGCAGTATTCTCCCATGAATCCTGGGGCGCAGTCGCATCGATAGGCCTGTACGAGGTCGACGCAGGTTGCGTTGTTAGCGCACCTGTTGTTGGCACAGTCGTCGACGTTGCTCTCACATCGAAGTCCCTTGTACCCGGGGGCGCAGTCGCAACTGTCACACACCGACTGAACGTCAATCGAGACATTGAGCCTGACATGCGATCGCGGTAGATCCGCCAAAGGTATCCTACCGCGGGCAATAAACCGCCAACACTGCGTCTCTTCTTTCTACTTTTTTTTTTCACGTTTATAACACGTCAAGTTTGACAATTAAATGCTTCTACTGTAAAACGATCGACAAAAATTTCGGAAAACTAGAATGATGCACTGTCTCCGACAAACAAGTTGCATGTGCAGTTCGTTCTCTATTATTTAGTTCAGTCTAAACTAAACTTATAATTTGGAATATAATTAAATAAATAGTTGATATATATCAATAGCTGCTCATGATTAATATTGATGACTTTAATACGCGTCTTTAATACGCAAGTAATAAAGACGAAAATAAATCTACACTTCTACAGAATTTATTGTTATCAATCTTAAACAAATGTGCTTGTATCGATCGGACGTATAGTATATATGCTTGGCGCAAATAGCCGACGCATAAGTTCGGCTCTTCGATTTTTCGATAATCGCAACAGCCTCTCTGTTATGAGCAGGTTATTGACAGCGCCGTCGGCAGTTTATAGCCTGCAGTCGTCACTCCTCGGGGCTCACGTGCAGAGGGTCCCGTTTATTACGCGTATTGAGAGCTGGAATTTGACGAACGCCCCGATCGCGTTCCACTTTGGACGCCACTTTAAGCGGCACGGCGGCGCGTCGGAGTTGTCAAAATAGCATAGCAACTCAGAGAGACGGATTTTTTTATTGAATCTCCGTGGATTATTGTCAAATTCAAGCTTCAAGATGCAACGTTTTATTCGTCATAAAATCATCCTCCATCGTGCATATTTACGTCTACAATGGTGTCGAAACGAAGACTGCTCAAAGAACTACTTGGTACACGCGAAATGATTTTGGTGGCGTGCAGGTTCTACTGATAATTCTACGATTATAATATCTACACTTTCCGTTATTATAATTACACAAATAACCAATCTATATTTTTACCATTTGATGCCTACGGTAAGATTCTTTAATTAATTCGAGATTAATGATTTAAAAATATATTGACAGTTTTCTATGACAGATTCTACATTGTGCGCTACGATTGATTGTTATTTACTCGGTTCTTTCTTCAAACAGTGATCAAATGAACAAAACTCAAAAATTAATAGGTTTGTTCATTCAAATAATGTTTGAACGCGCGTTCGTAAATGTGCTACATAACTTTATGATGAAATTCGCGAAAATTCAAGCAAGGGGCTGACGTAAAAAAGAAAAATAAAAAAACTACAAAGGTCGAAAAAAAGTTATCTAGACATAATATGATACGATGCTGTCGCAAACGTTCTACGGGTTCCACTGAACGAGCAACTCTAAAGTCAGCCCGACGAGCCACTACTCTGATCGAGCAGTCGTGTTCAGTAAGTACCTGAATCTTCCTTCCTCCAGTACTTTGCAAGTTCCGGAGTTCCTGCAAGGATTTCCATAGCACGCGTCAATTTTATGCTGACACCGGTCCCCGTGATATCCTGGCGTGCACTTGCAACGGAACTGCCGGTCCGGAAGCGCCTCGCAAAATCCTCCGTTTTCGCATGGCGAGGTGTAACACAGGTCGCACTTGGCCAAGACTTCGGCTGGCTGCTGCTTGGCTGCGCGGAAGAAAGGTCTACGATTAATGAGCAATTTTAGTACCCTACCGTGATATTGGGCCAAAAAACCACGAACTAAACAGACTGCGTCGCGCTGTACTACGAAAAATCAAAAACACCGTCACGTGCGACAACCAGTATGCGATTGCGGATCAGTAATGGCCAAGCAATTAGAGGAATTTTTTCTTCTCTGCTTCTTACGAGCTGCGTTACGAATTGCGTACTTAATGTCGTTAAATAAAAAAAAAAAaTAAAAAAaGTATACTTTTTACGTCTAATGGAAAATCGATGTTCAATGACCCGTTTTACAGCAAAGTCGTTACCAAACGGGATAATGATTTGCATTTCCGACTTCAACGATAAATATTCTATGGAGCCGGTACTACTGAATGTTAATGAATACCTAAGTAAGAATTTGAGATGAAGTCGAAATTGTGGACAAACGATCGCACGATTCTACATCAATAAAACATTCCTGCTACACGATTCGTGAAGAGCGATTAAATTTATTTGGCAGCAAATAAAGTCTCTTGGCCATTCTGCCCGCAATCGAGATATATGCTTATGAGATATTTACTTTTGCATTGAAAGGCACTAGCCGGCGTCGTCAAAAGTAATTTGTCTCTCATCGCGGGTGGTTCCATGCACCTAGCTATGCCAGGCTCCACATAATCTTTCTTCACCCATTCGGCCAACCATCGCATGCTGCAGTCGCAGTAAAGCGGGTTGGACCCCAGGGCACTGTAAACATCATGATCGATAAATGGATGGTATCGAAAATCGAGTGCGTGTGGTTTACAAACGGAGTGATACTCACAGATGTGTTATAGACTTGAGATCCTCGAATGCTCCCTCTGGGATCACTGATATGTCGTTACCGTGCAGCGAACTGAAAATGGCAATTAAATTGTGTAGCACACCATTTTATTAAAATTGATTTTAATTTGTGATTTTATTCGGAAGAAGAAAGAGACTAAAATAGCAATAATTTATTTCTATTAGTTGTAATGTCAATAATTAGCGTTATGAAATTTTACTTCAATATCTTCCTTTGTAATTAATTATTTATATCGTACTGCAATTCAGATTAAACATTCCTTTAATATAAAAATTTTATTCGAATTTTAATATATGTTATTTTCATTCAATTGACAGATTTATTAAATAATTACGATAATTAAATAGTTTTAATTTAGTAGAACGTTGAGTGTTCAACAATCGCCGCGATCGTGCGAATGCTACATAAAAGCGCGTTGGAACAGATTTTTTCGCGGCAGTAAAAGAGGCACGTCATGATGATAACAACAGTCGAGTATTTGCACACGTGACTTACATTATTCGCAGGTTCTTCAGTCCCGCGAGAGCATTTCGTTGCACGCACTGTAGTTTATTGTAACTGATGATTCTGCAAAAGAGATTCGTACGTCGCCCATTACATAAACGGTTTCGCGAGTCTCTCCCGAGAACCCCCGGGGTAACGGAATAAATATTCGACTTACAGGTGCGACAGCTTCGTGAGATTCTTGAAGGTATCGTTGGACAGCATTCCGATCTGGTTGTTGCTCAGATCCCTGAAAACGAAGCGGACGTTAAACACGGCGAAAGCCGCTTGAAAGATATACGGGAGAAGGTGCACGCGTGTTTTATTTACAGTCTGGTGAGAATCCTCAGGTGGTTCAGCCTCTCCGGCTGGATCGTCTTGATGTCGTTCACGTCCAAATACAGCTCGGTGGTTTCCGGTGGAATCCCGCGTGGAATCTCTGTAAGCTGAGACCTCGAACATCTCACCACCGAACCCGCGCAATTACATTGAGGCGGGCAGTAATCGTCGCCTAGGCAACCCACGCTGTCGTCTAGGTGTAAAATAGTTCGTGAATCGTTAACAGGATTTGCAATTCAAACGGAAATCGCGAATATTATTTTGTCAATGCGTATAAGAACGTGCAGCGAAAGCAACTGACTTATTCGTGAAAATTTTTTTTTtCGCGAACGCGCAGATATGTAAATCGAAGGCATGAAACACGCGTTATTCGCCAATTCAAATTTAATTAATGTATTATATTGATTTTGATTTTGTATGCGTTCGTGAATCAATTTGCATGCAAAGCCGCTATCAATTTCACATGGGATACGTCATGTTTGTATTCTATTTTGAATTTATAGCGATCGACGGCAAAACGCAATGATACAAATTGCGAGAGTAAGATACATCTACAGATGTGCTACAGGTGACCTAAATCAATTGTACAATAATACATTAAACGCACTGTTGCATTTGAACTCGTGGTGCGGAATGTCCTTGATGATGGCATCCTTTAATCGCGGTGGATCGTGACAACGGCCAGTGATTCCGGCTATATCTCGCTTCCTCAGCCACCCGGCGAACCACGCGAGATAGCAGTTGCACGATAACGGGTTGCCTTGCATGTTGCTGCAGATACCAAAAAAATATATCAAACGATACAGCAACAATAAGAAGGCAGTAACACGGAGATTATACTCTGATTATTACAGCTGATATGTAATTATTTTTAAGATATAACAGAACGTAAATTTTTCCGGCCGCTATACTGCCTGCATATTTTACGAAAGAGATAATGAAGAATAAAAGAATATGATGCAAAAAGATAATGAGAAAGTTTACGGATAACAATGTCTGTGCAGCAATAATCTTGTTGCAATTTCATACGTTGATTACTCGCGAACTTACATGGAACGTATGTGCGGCATTCCTTCGAACGATGTCGGCATAACGCACGTAATGGAATTACCATGGAGATTCCTACGCAGAGTGAATTATGCGAGTAATCGTTTACTCCATGATAGCGTTTTATCAATGCTAGATGGTACATTTACGCAACGTGGTACTTACAGTGTTTTAAGGCTCGATAGGCCGGCGAACATCTTGTTGTGTACTTCTCGCAGCCTGTTCTCGGACAAAAGCCTGCGGAAAGAAAGCTCGTCATATCGTGAAACGAGGCGCACGACAAAATGGAAAGAGATTGCGAGCTAAGTTGCGCCGCGTTACAATTCGCCGTCACTTTTTACGAGTCGATAAATGTCATTTCTTCGAGCAAACGAGCGTACGAGCGTTATGAAACATCATGAAAACACGCGGAGATGTTTTTAGCGTAGTACCACGTGGTGTGTAACGCTTTTATATTCTTTAAATTCCGAACATAAAGCATTGCTCGATTTCAACGTGTCTTAAAAATGCAGCTATTAACTGTATGAAGAATTTATGACGTTATATATTGGATTATAAATTGCACCTATTAAACGATAAAAATGGCTCACGTTGCATGTTCAATTTCTATATGTCATCTAATCTTTCAAATATATAATCTTTCAATATCTTTTTAATATAATCGATATTTTCAAGAAACATTAATTATTGATAATAACAGTTATATCGCTCATGTTGTTGTAACAATGAAAACATTGTCATTTTTTCCCAATTAGATAAAAGAAGAGAAAATTCTTAAGAATTTAATACACTGACTTGAAAGCTAATGATATTTTGATTTCTTTATAATTAGTAGATCAAATTATTACATCAAAATTGCAATTAAAAATAATATTACAAAATTTTCATAATTTCAAACATTCAAACTAGAAAATTTTATTTTTTtAGTTATATCATTGCTATATAAGTAAATGAGCGATAGATAAATAAAAATTAATGTACTTGCAATTAAATTTGACAAATCGTGACTCGCAATGAAACAAACGCTATATCACTTGAGTCTTTGATGAAAAACCGTCGGTATTGTTTTAATAGTCGTGCCCGGAGACAATGAGGCCTTTTCGAAAATTCCCCGAGAGATTCTCTAAAGTTGGAAATATCGACTAGGAGGCCGCGCAAAGAAAACAATCTTGGCGTTACACAACGGTACTTCTAGAACAGTTTCTATTGTGCCGGCAAAGGCGAAGTTTTCCGGAAAGACAACGACGACAATGTCGCAAAGAAGGAGCAAGTTGCGCTGTGCTGTGAAAGCAGTATAATTCGGACCTCGCGTTGTGACTTACAGGTCGGTGAGATTGTGAGCCCCTTGAAAAGCGGACGCCTCGATGCGGGAGATTTTATTTTTCCTGAGATCCAGATGTTGCAGCTCTGGCAGCTTCTCAAAAAGACCATCTGCTTTGATCTTGTCCAGTTCATTGTTGCTCAACAACCTGGCGTAGACACACAAGCGGAAAGGAATGTATGTAGAATGAAGTCGCGACTGTCGTGCCGTCGAATATGCATGCGTGTTTGCGATATGCATGTATGGTTGGTTTGTTACTCGACAaCGTAAAAAAAAAAAaaGAGAGAGAGCAAAATTGGTACTTTCCGTTCGTTACTCCATCACTTGTTTTCGACTACCCACCGAGCAATTTATTTGCTACCGCGTTATAACAATGCGCCGCTCAATAAATTTTGCGAATTGTACGCTGGAATAACTCTCGTGCAGAAATTGGTGCGTTGCAGAATGTTCGTGCGATACGTATCGAGCAATAGTGTAACTTGCAGTTGATTGTTTTGCTTCGTTCGTAATTAATACGCTCTAACATTCGGATAAAACTATTAACTTGGGATATGTCGAAGTGCAAAAAAATGTTTCCACGCATAAAATAGAATAAAATAATAAATTGCTGCAGCAGTTTGTTGTTTTATTTCTAAATCGGATAATTTAAAAGAATAAGATGTGATCGCGGAAGAATGAGCAAATTTTACAATGTATATTTGCAACGTATGTTCAATGATTAATTTGAATGCAAAATACAAATAAATAGAGAGTAGCAAAGAGATAAAAATTAAAAACTACGTGTTCGCGAATCGAACTTTGCTAGCTCGAGTTCGGTGGAACAAACGGCTGATTCCGCTCCGCGAGAAGCGACGATGCAAAATTTGAAATACTTATTTAATTTTGAATAGGCGCGAACGATTTGCCGAACGGAATTGCAAAGAAGTAAAATACTAAAATATAATAGCGTGAATCTAATTTGACTTTAATTTGCTACGATTCTTAACATTATGTAAATCAGAGAAACATTAATATTTTATGCGTATAGACCTTATTGTGAGGGTTGGTGTATTGATTATTGAATGGTATCGAGAAATTAATTTTTTTTTCATAAGCGTCGATTCATCGAACGGACCAAATGCGTAATTTACTGCGAATAATAGTTCAATCTTCATTGTTCTTTTCCCATTGCACTCCACGATTTAATCAGATGATTATCTGGTTCAACGATCGAATTAATATTCGAACGAAGGGATGAGAATTCTCTACAGACGAATGATATTCATCCTAACTACTCGTCTGGACGGTCCCGACCGTCCCGATCGATCGGCTTGTCCCAATACTCGACAATTTGAACACTTTCTCATAGAAAAGTAATAATAATTCAGAATGCATATCAATCAACGAATTGCTACGTTAGATTAAACTAATTGTAAAATAATTGTAAACCAGAACCGTACCTAATTGCAGGTCAGAAATTGAAAAACAATGTATCTGTTCGTAATAAATCAACGAAGTTTGTTCCAATTATTTTCAGTATTGTTACCCATTTTGATTATACGGGCAATTTAATCGGTTTTTTTAATTGTTAGAAATTACCTTCGGCATTACATCGTTTTGCAATTTCAATCTGCAATTCATTCATTAACGATCATTAATTTATACATATGTCTATGCTTATCATGTTAACCGTTGCCATTAGCTGGAAATAATTATGACTAGCGCGAATGCCGGCGACTATCATAATTGTCGATATCAATTATTTTTACATTCTCATTCCTTAATATTGCTAATATTGTAACTTAACACATATACACTAAGAAAAAAGTTGAAATATTCAAAAGCAAATGTTAATTGTGACGTGTTTTTTTTATATTTATTAGTTATAAAATATTTGTATGGAATATACATTTCTGTGAAATATCTCATTTTTCTTATTAATTGGTTTATTTGACAGGAATAAAATTTTCCTATATTTAAATAAGAATTTGTTCTAGCAAAATAAATATTATATTTCACAAATAATTTTTTCCCCATAATTAGTGTACTTACTATATTCGTAAATGTAGTAATTATTTACAGTATTCATTATTTACATGAGTAAATAATTTTTATAATTTGCAGATATTATTAGAAGTGTAGCATAATTATTATTAAATGTAATAAAGTATAATTATTACCCATTATTTATTAAGAGCGCCTTGTTAAATCTTTAATTACGAGAGGCAGCAATGCCTGGCAACGCTATTATTCGGTATCTCAATATTGAAGGCTTAAATATTTTGATGGAAACATTTTCCTTATTTTAGATCGACCGGCTACCTCTTCATCAGCGCGATGTCACACAGTATTTTGGGAGGCACTAAAAATGTTCGCGGTGCAAGTGCGTTCAGCGTGACAAACATAACTGCACGGAATATATTGCGGATGCTGCTATATCCTGTATGACATAAATTGAGTTTGCCTTTGGTTCTCTCATTTTGCACGCCCACGTACATCGTTCAGCGACATAACGACAAGTAAAATATTGTTAGTGGAAGCTTTTTAATAGAAGCTACGTCCTTTCCTCGTCAAGTTTTTTTCTGTTACCAATGATTTACTCATCAACGATGAAGAAGTTTATCAGACAGGACTTTGATAGCATCAGCGATTAGTGTCGAGATTAACAGAGCGCGTTCTTTCTCTGGTTTTCACGCGTGGTGGTTTAACACGTCAATTAAGAGAAGTATACTTACAAAGTCGACGTGTAAAGCGGCAAGTCTTTCGGTATCGCAGTTAATCTCTTGTTGGAGCAATCAACCGTCGCGCCGTTGCATGTGCACGGAGCGGGGCAGGCGCCAGGCAGAATGCACTCGCCGGCCCTTTTTGTTAATAGCTCCTCGTCACCTGCGGACAAAGTTTCTGGGTAGAGTCGATTTCTAACAATCGCGCCTGAGCAACACTTCCGCACTCGATCACGACTCTGCTCCGACACACGACGGGCATATAATGTATACACGTCGTCCGCAGAGCAGTCGTGTGATATCCCGGCCACAAATGAATGCTGCGTTCCTTCGTGAAAATTACGTTGGTCGAACGTAATTATATAGTAAACGTAATGATGATGATGATGTCGATTCATTAACGATAAATTTTGATAATGAACAGTGTAATTAATGGCGCCGTTAAACGAAACCACCCGTAAGCGTGATGCCATATGTACTTGCACGTTAATCGAGTGTTTAACGTCGTGCGTTAGTGTTGAGGGCTAAATATGTTTATGTATGAGTGCGGGGCTACGGCAGAAATGATTTATCATCATATTATACACCACATTACAAATTGCCGGGTGTGATGTACGCATACGTAATTATATCGACGATACACATTGCCACAAGTATAGGCCAGCATCTCGCATAGCGACTGTGCTTTCTCCGACGGTGCTCAAAGTACAATAGCGCTTTTTACTCGTCGATTGTCAAAGTTAAAGAGAAGAAAGCGAGAAAATTAAACGTCACCAAGAGCTGATTTTTTTCTTTTTATCGGTGTGAGCGGACCTGCGCTTATTAATCCCTTTGTCACCATATGTTTTCACAAATAAACAAAATTAAATATTAAAAGCTGTTGATGATAAAACTAATTTAAAAAAAAATGTTTATTGTTTCCATATCAAAGAATAATAGAACGGATATAAAAAATATTCCACGGAAGTACAACAAAGATATATAATATTTATATTTTATATAAATATAAAACCTGCCAAAGTTTTGCTTGAAGCAAATAATAAAATGAAAAGGATAAATAATAAAAACCAATTTGCGTATTTTGTAAACAAAGTTAAAATTGATCGATTACTCTCCGTTGTCTCTTCCGCCTTCCGCTTCGCCAATACTCTTACGTAGTTGGATGGGAGTGCTGCTTAAGGAGCAACATTTGTTTCCTTCTACGAAAACTAGAGAAGCACTCTCCTCCTAATTCTCGCGAAATCCTTCGTAATGCAGAAGCAAGGGTATCGTGTAAATTTTTGCCGTGACCGGGGGGCGCAAGTTGCGAAAGTTGTCTACAAGCTTAACGCTCGAAACGTAAGTTCCTGTTTACGGAATTGCACGTAGCAGTTATGCGCACATTTATACCAGCATAGGTGCACATATGCGCTACCGAGGTATTTATTTTTCTTAACTCTAAATTGAGTTTCATGTACACATAATAAGGAGTTAGTCACAAGTAGTGAATATTGCCTTTCTTCAGTAGTATTAAATGTATTCGTGCTGCTTGCATATACGATACAACAAATAAATAAAATACAGCATATTGAATATTGTGGATATTATTTAAAACAAATGTTTTATCTTTATATAACATTATTAATTTGTAAATACCGTTAATGATATTCTTGCATTTTATAGTATTTTAATAGCTTGTGGCATTTAATTATGCATCAAGTAACTTAAATTTACTTTTTAAAGGGTGCGTCAAAATTGATTGCAAGATAACTTTTTTTTTTTtATTATCCAAAGCCTGTTCGTGCGACTATTTGGTAATCAAGATGTTAACAAGCAAGATATTACACCGTTCAGTTGGGTTTTTGTACCTCACTCCTGTATAACCGCGTGTACATACAGTAGAACATACGTTTTTCGGAATTGTATAGCATACAAGGAGAGTGCATCCGGGTGAAACTTGAGGCCGCATAAAGGAAGGTTAGATACTTCTGGGTATTATTCTCAAACGGATACTGCAAGCACGGATCTCCTCGCAAAAAAATGTGTCGTAAAAGATGCATTCTGCAAAGGGGACATTCGTACGCTTGTGATAAATTTCCCTAGAATTACGGAATTGCAAAAAGACAAGGTAAATGCAAACGACCGCACGATGAAAATAACAGAGAAACATGGAATTCTCGTAATTCCGGAAGTCACGTATCAAAATTTACGGACTGTGATATAATAAACACACTATGAGTGCATCATTCGTTCGCATAAAACACGATATATTTATCGAAAGATCGCTTTTAATTAAGAAAATATAAATTTGCCTTGATATTGTTATGTTGTAACTCTAAAATACCTAACTTCTTAAAATTTAAAGATATGAGAGAGAGGGACGTTTATTAAAATTTTAAATAAATCATCGTTTTCTTGACTTTATTCAGTATTTGTATACGTCACGTCTTAACGGAATAATATACTCGGAATAATATTTTCTTTCGTAAATACAAAGTTTTTATGAAAAGAAAATTCTGTACGTCAACAGAAAAAAAATTTTTATAAAATGTATCTCCTTTTAAGGCACGATGCCAATTATTGTCTGTATCTGTATGCTTCGTTTTGTTAATGATTACTATTACTATACAAGCACAAACGAGTTTGCAAGCGTGTCTGCGAATGTACATAATAATATCGGTTGACATTAATGCATACCGGACAGCATTATGGTTAACAAGATACATCCATCGACAATTACATGCGCCCGGCAAAGTGACCAGCATTTATCCTACCGTGCGGGAACACCTATATAGATCGTCTGGTCACCTGTTCCGGACGTGTCGACAAGAACGAAGAAGAATCGAGACAGAGAGAAAGGAGAAGACGTACGTGTCTGGATGTGTGATGCAAGAAGCAATGGAAACGACGATGGTGGGTGATTTCACACGAGTGAAAATGGAAACCGTAGATCGTTTCGGATGCGGCACGCCGCCGCGCCGTGGGCCATCACGTGTGATTGATAATAAAGTGATGCGATTGATCAGTTTCAATGGCTTGGCATCGGTTTTCGATATACCCTTTCTTAGCGAAAGAGCGAATATATTAATTTATAAATGGTAATGTAATCCGATTTCTCCATTCTGCTTATTCGCTTTCTCTTACCTTTCATATAAGCGTAAGATAAGCGCCACTTTCAATTTTTGACATTTTAAAAGCCGAGATGAGACAGATGATAAAACGTTATTTCCAAATTGTATTGATGCAAGGATGGATGATTAATTTCATACAGATATGAGTATGAACGTGAGTGAATACATATATGATACATATATGAAGATTTGAAGATGAAATGTAAATGAAAGTCAGCGGATAATAGGGGCCTATTTACATTCATCGTGCAATATATCTTCCTCCACATAGACTACCGACCTGCATATTATCCTGCCGAAGTGTTACGAAGAGATATACCGGAAAAATCGAATTGTGCTTACCCTTACATTTGAACTTGTCGTCCCGCATCGAATCGATCTTCCGTTTCTGCGCTCTTTTTGGCGTGTCGCATTTCGCACCGGATGTCTCTATAGGATGCGCGTGAAGATACGCGCTCAGCCAGCGTAGATTGCAATCGCAGATGAACGGATTCCTCGCCAAGTGTCTGCGAAAAAAGAATCGAGTTACTGACTGGAGGTACTTACAATGCAGCACGAAATATCTGCTTCGTTAAATATTTTAACAGCAAGAAAGTTTTTATACATTCGCCCAAGTTAGGAGAGGAAAAGTTTGTAAAAATGTTTGTATTAATAATACGAACAATGTTTTAATGCTTCGCAGGTTGGCAAAAGTCCCATTAGCTAACGAGCGTATATTGTTGTCGTACAAAGATAGTAAGGTGAGACCGGTTAAGTCTTTGAACAGGTCTGTTCGTATGCATGATATCTCATTGGCATTCAGTAACCTGAAACAATAAGTTTCGCTATAATTTCCAACAGTTGCCGCCTCGTTGCAATGCTTCACGGCAAAGCGAGAACAATACGTGAGAAGCCATGAATAAAAACATTTTCTTCAGTGGTTCTAATATGAATTATTAATTCTCGCCTCCTTAAAGTCGACTTCGCGTCATGCAACAGAAAACTATGCCAATTCCAATTTATTAACTTTAATAGGACTGACTTCCATGCAATTATTTACTTTAGTTTTAAATTTTGTTCATTAAGTTTATAACTTTCTTTTCTTATTTACTCACAATAACTGCAGATTTGTCAGGCCTTGGAAAAGACCAGCTGGCAGCTCCGTGATTTTGTTGCCATAAAGAACTCTGTAACAAAATGACGTTTTCTTGTTGTTGTCAAATGAAACAGAATGTTATTTAAAATGAATCGATAATGGAAAAAAGATGCATACAAGGATTCGAGGGACTTCAATCCATGAAAAGCATCCGCTGCTACCTTTTTTATCTGGTTGTTGCTCAGGTCACTACGAGCAAAACACCGGAAACAAATAAAAGTATTAAGCATTGCGGCTGACGTGCGCAATAGCTATTTGTGTTGTATTTATCAGAGTAAGTCAGTCACTCACATTCTTCGCAATTTTCTATATGGCGAAAAAGCCTTGGGTGGAATTTCCGTGATGCCATTTTGTTCCAGCCGCCTACGGGTAATTATGAAAAAaCAAATTAGACAAATAAGTTAGCAAATCTGCGCATTTACGCTAGTGAACGCCTCACAAAGCTCCGAGGTTATCGATCGCTCTTTGCTTGTTCACATTATTTCATGTTTACTACTCTTTTCTGCTTCTCTTGCTCACATGAAAATATAGTATTTTGTTTCACGTGTTTACACACATCACGCGTATTAATCTTGACGGATTTTACAAAATTATTTGTTGCTATCGGTTTTACACAAAACTATTTTAGAAAAATTACTAATAAAATCGCAAATTTATAAATAAAATATTTAAATAAAAGGAATGTAACAATTGGCACTAATTTGTGCTGTATTTTGTGCAACAGCTACATACCATATAAGAGAAGAACTAAAGAGTACTCGAGAGAGTATAGTTCAGTCAATCCGTGTTATCGATAATACTCGCGAACGAGAAATAAATCTCAGACGAAGTACAGGTACACAATGCGCGAACACGGCGCAACGGTTTTACTTACAACTCAGTGGTGTCCTCGGGTAGGTGGGTTGGCACTTTCGTCAAGGAGTTTTCTCTGCAATCGACGATCCCATCAGCGCATTTACAAGGATGCGGGCATTGGGGCTCAGCGCTGCATTCCGATCCCGTTCGCTCGACCAGGCCTGAACACTTGAACTCGTGCTCCTGCAAACAATAGGTTTAGAAGTCGTGTTAGGGGCTAAGTGGGTTAACAAGAATCAATATCGATGAACTTAACAATCGCAGAAATGTTTTATAAAAATCTTCTTTTCTCGTACAATGTTTAGTTTGATAATGATACATCTAACAGTTAAATTATATGCGTACGTGCAGACATGTGATTTAATAAGGACTACATAAAAACCGTATATTTATGTATTATGCAAATGTCTGCATAAATTCTGACGAGAGATAAATGTTTGTGGGTTTTGCATAACCAGAATTCAATAGTGTAAGTCTCTTTAGCCGGACTCACCTGCACATCGGCAAGATTGCGATCCTTGAGATGAGCCGGAGATGCGCAACGTGTATGTTGCCCTAGGCGTGAATGAGCCCTCAAATGACGCGATAACCATGCTAAATGGCAATCGCAAGCGAATGCGTTATCCGCAAGTTTCAAAGTTCGCAAATGCGACAAGCCGTTGAGCATCTCCTTGCCGAGCGTTACAAGTTTGTTGTTGTTCAACATTCTAAAATGAATAATTAATTTGAGCACGTTTATATACTCTCCCGAACATGAAATAGCATTGTTGTAAAACATATTATACGTTCGAATAATTTTAATTCTTTTAATTTCTCTAATATACTTACAATATTTCCAAGTCTTTCAGTTCTCGTATCGAAGCCTCGTCCACGCAGGTCAACACATTGTTGTCAAGTAACCTATGAAGAGTAAAATTTTATAATTTTAATACATAAATATATAAATATACAAAAATTTTTtAAACTTTTTTTtATTAATAAAaTTATTATACAAGAGAGATCAATTATATACTTCAAAGAAATTTTATAAGCTACGCCTAGACTAATAGAGTTGTCTGACCGTGCGCAACATTTTACTACTTGACACAGAAAAAAAATGCGGCTAAGAACAATTATAATATATATTACAATAAATTTAAAATACAAACTTAATTGTAAGTTTTATCTGAAAAGGATGAATAAAATGGGATAATTTTAGCTCTCGTAGCGACAAGAAAAATGATATATCTTTTTACAGTTTTTAAACTGTTTCTACATTTATTTTTTACTTTGATCTTTTTTATTTTTTATTTTTAAGTATTTGTTAGTAAAGTATTAAAATTGACATATAAAATTATTAAATATTTAGTAAATTGTTATTGTTGAGCTTTGCGTATTAATTTACGCATTTTACTGTTAGTAAAACATGAAAATAGTCTCATTTCTAATACTTCTTTAATAATTCATGTTCTACTTGATAAAAAAAAAAAaaTTATTGgTATTTAAAAACATTAAAAGACTTTATTGATGAGATCTATTTTAAATCTTAACTACATTATTTGAAAACATTGTTATTTATTATGTTTTATTCTCGGAGTATTTTATATTTTATTGTAGAACATTATTACTGAAAATTATAAGATTTATGCAAAAAATTTTTAAGTACCAAGATTTACTTTGATAAAGTAAGGCTCTCTTCACTTATTAATACGTGTTCACATGTCGATTAATTTTTACTTAAAATTTTTTATTTTATATAGTTTTACACTTTCATTAACATACCATTCACATAATAGCTTCCCATGTGTTTAACAGCTTTATATACTGATTTTAATATTTTCCTGACAAATTAAAACTTTTCAAAGATCAGAATCAGATTTAGCAGTTACAAAAGTTACAAAAAAAAAAaCATCATTTTTATTTACAGTTCCGGGGCCAAAATCGATGCATTTTATCCTTCTTTATCTGTAATGCGAGTAGAGTTGTCATATGTAAAACATCTTGAGCATAGTTTATAATGGGCTACTAGACTGTGACTAAATGGTCTCGAGAGAGATTGTTACGGAACAATCTGTCTTTGTGGCAAGCACATCCGATAAGATACTTACAAATGTCTGAGAGCGGACACTCCTCTGAGAGTCTTCGGTCCTATGGTGGCGATCTGATTGTGGCTAAGATCTCTGTAAAACAGAATACGATTTTTCTTTTCAAAATGTCCGATTCTGATTCATCTATTATTTGCTTTTAATCATAACTGTAATGTTATCTTAAAAGTTCATCTATCTCATAAAGTTATCTATCATAAAGTCTAATATTGTATTTAATGTCAGTAAAATAGAATCAACTTATAAAAAAATGTAACTCTATTACGTACAATTTTGAAAACATTAAAAATAAGGATCTTTCTGTTTTAAAACCTTATTCTTGCTTTTTTTAATTTCTAAATGTTAAAAACATTTTTAAACCGAAGTTAATGACTAATAATAATACTTTCTCTCTTGCTTTTTTTTTCAATTGCCACGTTTTAAAAACATTTTCAAAACGAGGTTAACGGCTAATATGATTATGGCCATATTAAGAACGCGCTTATAAGGATATTAAAGCGCTTTTTTGATTATGCCATAAACATTTTTATTTTACACGACTATTTTATCGTTCATTAAAATAAAGACAGAATTACAAAAAAAGTGTGCTAATGTTTTCTAAAGCGCGTTATAAATACAAACCCTTATATGTTTAAAAGATACTTTTTTtGTAAAAATGTATTGTTAATTGGTGATGCGATGTTTAAGAGTTCTATTTCTATTTTCAACTTGACTTGTAAAATAAATTAAATCCAATTTCCAATCGTACTCGAAATCAGAAGTGTCTTGTCCCAGTTTTCCATACGTGTGATTGTTGCAGGAGTGTATTCGAAAACTATTAGAGCCCATCGGCGTCACGTTCGCGTTAACTCGAGACTGTTCAGTGACCTTTCAGCTTTTATGTTCTCGAAGGCGGATGACCACGTTTACCATCATCGGTGCAACACCCGCTCGTTCCACTTTATTGCAGCTGTAGTCGCGAGTTCGTCCTACATTTTCGATCAATTATTCAAGAGCGTCGAATGTCGCGGCAAATGCCTCCTTGCGGCGTATACATGATTATCCTCCAGAAAGTTGTCGCTCGTGCGTGTGACCGGTCACACGTGCGCCAGACCGTCACGTGAGTGGCTATAGACTTCGCAAGTACTTCTCATCGCGGTTGGGATCGTTACCCACGTAACGATTGACCATTTCCACGGTCTCACGCGACAGCCGGCGGCTGCTTACGAATTATTTTAACGAAGCCACTCGAAACTTGACCCAAAATTGACTCGCGACAAATTTAATTTCTAAAAaGATATTTTTTTtAtACGGATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGATGTTGATTGTTCTTTCTTTCCAGACATTCAAAATTTAACATTTTTTAAATATATCTTAGTCATACTGTATCTGAACATTATATTAAGTGACATCTCATGTATATCAAAATGATAATACATATCGTTCTATCTTTTTTGCGGAAATTACGTAATTAAATACGCTAATGAAAGAACGAAGGGTTAGCAAATAATTGAATTGTCTCTCATTGATATGGAAAGACACCTTCGAACGATCAAGGGTTAGACAAATGGCGCGGTTGGAGACCCCTCGAAAAGCGTGCGGCTATCGTAGAACCTCGAAAAACCTCTTCTCGAGGTCTGAGTTAACCAGAGGCTTGTGATGATAGGTTGGGGTCTTGGAGTACGGCTTGCCATTGACCATCCATTGGCTTGGACCTCGCAATCTGTAATTATGTTCGCGAGGGAACGCGAGGGGGAGGCCGTGGTGGGCGAGAGAAGAACAACAAAAACGCGAAACGGAGAACGAGGCAGAGGGAGAAGCGCGGGGAGAAAGAGAGAAAGGCGACGAGGGACGTAAGGTGAGAGTGCGAGACTGGGAGATTGAACTCCCAGTTCGCTCGAGCCAATCCAGAAAGTAATTACCGAATTTCGACGCGCGCGCGGCCACGTCTGCACCGAACGCACAAAGGGAACTCGCGTCATTCGCGTTCGAGTTGGTCGGCGCGAAATATTATTGTCCCCGTAGAGTTTGATCGTGCCATCGAATAAACGTTTGTCACACGCCGCGCAATAAAAGTTCATCTCTCTAGAGTACTTTCGCGGAACTATGAAACGAATTAAAAACGGTTTTATAACTATCGATTATTGATCAGGAACTTTGTACTTGATACCATTCCCATTTGTGACTTGTTGGCAAAAGTTTTTGTAAAAATGATTTCAAGAGAAACGAATACTCCTGCTAATGAATTACATGTATTCCATTCCTCTGAATTTAACAAATTGGAAGGAAGTGAAACGAGAAACGCAAGAAACATGAGAGTGGATAAGCTGGAATTGAGTATTTGCACATACAGAAATTTGGGGTATTAAATTCCCACTGCGCCTGATCCAATCGCAAAAAGCAATATCCGAATTTCCAAGTGCCCACGTTGATTCGACAAAAGAAGCCTGCGTCGAAATTGCTCATTATTTCAAGCGATTGATTACGAAAGTCAGTGAAGCGCTATTGCACATAATCAGATAAAAATAAAATAAACGGAAATATGCGCATAAAAATTTTAATATATGTAAATTAATTCGTATTCACTAAAATAATACAATATATACCATTACTCATATAATAAATAAGCAATGTGAAATTAATGCAACGCGAAGTTAATACAACGTTAAATACCACATGTTCACAAAGACGAGGCATTCGAAATAGATTCGCGATGCGTGACATCACATCGTCAGAGTCGACAAGCTAGGCGAGCTCGGAGAATAGACGACGATAATGAGCTGCGACAATAATCAACGGGGAAAACGAGCATTTGCTTTATGTGCTTTGGGTTCGAGCATGTAAGCCGGGGAACCCCGGGAAACCTCTCGGTTCACTCGAGCCAATCCAGAAAGCAATTACCGAATTTCGACGTGACCGCGCCCGCGCGAAACTAACAAAAGGACTCGGTGGTCCTCGTCTCTCGCGAACAGCCTGTCCAATTCCGAATTGTTACCGTCGCCGCTAACTGTGTTACCGCGATAAGAACGAGACGAAACGAGATCCGACGTATCGCGCACGTATCGTTCACGTCTGTTTATCAGGAACCACCGCGCCTTACGATCTTTTTTCGTCCCGTAGCCTGTAGGCACGATTGCGCTGCCGCAAGGGATCGTGAAACTTCAGAGAGAAAGAGACAGAGAAGTCGATGTCGCGATGTCGAGGATTGTAATGTCTGGAGGACGACCGTGCATTCTTCGGACTCGAGCTCCGGAGCTTAGAATGTTACGCAGAAACATTTGTAACAACGCTCTTGCATATGTGGTAAACTGGTTTTAATAGCTTCCACAACGACGCCCTACGCTAGGATTCCTGGCATTTTCCGCTTAGCATACTTGCGACGAGAGTTGGAAAACTGCGGCAGTCTGAAAACTTCATGGGCTCACGAATGGACATTCTCTCGTGTAACCGTCTCTCTATCGTTAGTAAAATTTTGTTAAAAACTAATTTATTCTTTTTTTTtAACTTTACTAAAACATGAAGACGTGAAAAACGGCGTGCCCAAGGCAGTAGATAAAGCGTTTGATGAGCGTACGAAAATGACAAATGAAGTTGTTAACGCGGTTTTACATCCCGGGTCGCATATGCGACGTAACGCCATAACGTCGGGGATGAGAGGGATTTACTGCAAGGGCCGTGAAAGCTGTATAATACAGCGTATTACGATCGTCGGGATGCATGATAACAACTGTACGATAATTATTACAGCCGCCGTCTCTCTCCCTCTCGAGCGATAAACCGAGATTGTGCGCGCGGCTCCTTGTATGACGGGCCTATAATTTGTCGACGTCCCGAAAATCGCCGTGCGGCCTCCTCCGTAGTCTCCGAATTTTGTCCCCCTAAATCATCCGCGCGACCGCGCGCGGATTCGGTTCGGCGGACGTTTGTCCTGGTTATTATCAGCTTAAGCGTACCGCGGACAAATGCCGCACAGCGTCGTAAAATACCCAGCTTGCACGCTGTCCTGCGGTATCGCGTTACAGGCGCCGCAATGCGGCCGCATCGGGCAGAGTGATACTAATCAACGGAGTGTCCGCGCCCCTTTCCATTGTGTCAAACCATTTATTACCACGTGGGTTTCATCCTCTTACCGTATACCTTTCTACGTTTGCGCGATGAGTTAATCATACGTTACGTTCACCGGCGCGACCAGCCCTCACCACGGCGCGGCGGCGGCGTGCCCGCGTCGAATTTACGAGACGAGCGCATAATTATGCTCACGTAGCTTTTGGCTGTGCATTAAGGAGAATCTGATTAATCGCTCGTCCACTTATCAGACTTGCGATCCTGCACCGGTGGTAACTCTCTGATTCATGCTTGTTTGGGGATTTAATTGTATATAAGAAGATACGGATTTATGTACAAACGATTATATTATATATATTACATGTAACAAGATTTATTATATTTTTATGAAAGAGAGAGGTATAGAATAAGAAACGTATTAAAATAATTCCGAGGTACAGTTTGTTCTTCCATTCGCTCGTTTGAAACAAAAGAACAAAATCCGACATCTGGCGTCTTTGCAAAAGGAGAAGATGGCGAGTTTTGTAACGCAGAATCTGATTTAATATATAAATTAAAGAGAAACATCTTCGAGGAGAGAAAGTGCGGAATAAGCTGCCGCTGGAATTACGAGTTTCCGAGAGTTTCGGAATAGCGGCCGGCGAACGGTAGGCGAATTAGCATCCTCCACTTCGCGATTTTAACGCTGGTTTATCCGCGCCGGATGAAGGATTATCGCGCATCCGAAACGCCCGTGAGAATCTCGCCGTAAGGTCGCAACATAATACGTCCCTTTGTAAAGTGGCTGATCCAGCCTTATCGTCAGAGACTGTAGGTTGTGCCCGAGCGGAGCGGCGTGGCGCGGCACGGAGCCCTGAGACGGGAAGTTTCGAGTCCCGTCCATCTTGCCCACTTTGCAGGATGATAGATGGACGATCTCCTCCTCCCACTTTGCTTTCTCCTTTCCCCTCTTCCCCTTCTCTCCCCCTTTtCTTTTTtGCTCTCCGCCGCCGCTTCTCTTGTCTCTTCTCTCTTTTTCTCTGCTCTTCCTCGGCTCTCTCTCCCTGGATCCCGCCATCCTGTCATCCGTGACGCGCGCAAAGAGGAGACTCGCGCACTTTTCGACCGCGCGCGGCTGGCAGCTGCCGGGAACACCAGGAACCTCCGATCCGAACGGAAACGTTTCGTGCCCACTCGATCGCGATAAAGGCACGATATCGCCGCTCGTCAAGCTGGCCTGTCTCTATTTTGTTTTTCTCTGCACCGCGTGGTGTAGCGCGCGCGCGCGCGCGCGCGTCGGTCGTGCCCGCGTTTGATTGAGATTCTGGATCGAGAAGAATGTTACAGCGCGCGTTCGGAGGAAAAGCAACAACCGATGAACGGACAGACGAGCTGGGACGGCATAATCACGGGATCGGAATTTCTTATGACATCAAGGTGGCTCTTCTCGTTAACGAGAGAGGCGAACCGTATGTCGGATACAGAGGAAACCAGTCATGTTTCGCTGAGAAGAGGTCGGTTCGTCCTCTCGACGGATAGCTTATGGATGAGCATAATTTGTGTATACGGCTACGTGTTCTTTCGATATTATCGCTCTTCGAGATCATGGAGGCCGTGGCCAGAAGTCTCTGTGCTCAGAAGTATCTTTAATAAATTGTAACAAGTATAACCGGTATCGCGAGTAAAAAAAaTTCTAGTGATTTCTTTGAGCGTTTGATTGGCAATTATTTTTCTCGGTATTCATTAAAGAATCCAATAATACAAAATTTACTTTAAGTGCTCGAGATCGATGCACGCGACTGGTTTCGGACTCGCCACGCTTTATTAAAGATTCATGCATAACGCGAAACACTGATTTTATCGTTTCTAAGTAATGACTTCATCGATCCTCGTGCCTGGCAAATGTCTAAAATCGTACAATCCCCGCCCATTCATTTCGCTTCTAGTGAATCAGGTCTCGCGCTAATAAGACAGTGGGGAGACGATAAGCGCGCCCGTACCCAGGCAGCCGGTCACGTAAGATAGAAAATACTTTGGTGAGTCGCGTGCAGAAGCGAAATGCGAGCGTCGAGGTGACGGTGGTGGCATCGGCGTTGCATATCGAACGTTCGCCTTTAAGAAACTAAAGCCCGGGGTGAAAAGTCGCGTATGCAGCGGCGCGTACATTCGATCGAGAAGTCTCGCGTGGCAGGTTACACAACGCAAGCCCCCGTCGGGCTTGCGTTGTCCCTCTCGCGCGGCGGTACATACGCGGTAGATATGTAGGCCGTCGTCTGAAAAGTTTACACGATACAAACCTTCCCTCCCGCTACGCCTGTCGTCGCGCTTGACACAATGATGAGGAAGACGGAGAGGCAGAGACGAATGCGGATCGAGGTCGCAATGCACGCGTATGTATTATGCGTGCAGTCTGGCGGAATCTGACATTCGGACTGATCTCACGTGTAATTATTCTCCTGAGATTTCCCTTTAGCTTACCGAGGATCCCGCGCGATCCCCTCGCGCGCGAAATACCGGCGCGGATGTTGCCGCGATATTGCAAACTTTCATGACGTTGTAGACTCGTTGCAACATCGCTCGTATCTCGCAATGCCGCCGCGCCATTTACCCGCCGCGCGTGTTATGTACCGTATACCGCTGACAGATCGCATAAaTCCCGCGGCATAATACGCTCGCGGCTTCTTAACGAATTCTGTTCTTACGCTCGTCGATATCTCGCGCTGACGATAAAGCATTTCAAATTCGTAGTATCGCCGCAGTAACTCCCGTCAAACCTGCTGGCGAGACTCTAACGCGTAATGCTAACGCTCATGAATGTCGGAAGATATTTATTTGTAATTATATATTGCGCAAGTGAGGTTCAATTGCCGACAAATCTATTTAGCATCGCGCGTTCTCCAATCGGTCTCCCGTAATGGGTAATATCGTTGTAATAATTCCCACGGTAATTTGTTCAATCGTACTCACAGGCGTTTTAAGTTCATCATATTACTGAAGAGAAGATCGGGCAAGTGACGTATTTGATTGTTGTTTAGTCGTAGCTTTTCCACTGCCACCAGATCTTGGAAAGCCCCTCTTTCGATAGTGTGTATTTGATTGTTTGACAGCAATCTGTAAATTGAAAGTATTCTCGTGATATATATTATATAAAACCAATGAGAAAACGTAATATTATGAAAACGCAATATTATTGTAATATTATGAAAATTAATCACAAAGGATTTTATATGTCAATTAATGTATATTGATATTAAAATGACATGAAAAATTATAATTATTGCACATCTGACTTAATTGAGAGAAATGCTTAATTATAGTTCACATATAATTCTTGTTTATTTAAATTATAGCCAAACAATAAACTGTAAACATCAATGTAACATATGTGTATTTAATCAATAATCAACGAGAGAATTAAAAATCTACTTACAAAACGTGGAGCGTTGCCATGTCTTCAAAATCTGTCTTGAATATCACCGATACATTATTTCCTTGAAGGTCTCTGCAACAAAAAGAGCAAAATCAATGTCATTATTTGTCAGCACCAAGTAAAAAAATAAATTAACAACTCTATTATGCACGGTCATATATCGCTAAATTATATAATAATCCGACAAAAAGAGTATACACGTTACTTCACGTGTAATCTCAAGAGAAGGGTATCGTGTAGGTAAACGTTCTTAAAAAAAAAAAaGTTTCGTTCCTGACACGACGTAATTTTCACGCCACCAGATTCCGTTGACTTACAACTCTATCGATTCAGCGAACTTAGTTCCGCGTTGCCACCCTCGACGCGGAATAAAAGCTGAACAATCGTACTACGCGAGGAGTGGAGATGACGAGCGACGCGGTATCGCCGTTCTGCCAATAAAGGGTTATACCATTCCGTTACGAGGAAGCGTGAATTTACTCTTCACGTCGAAAAAGGAGAAGACCGTGAAGTAGCCGTCAAATACAGCCGTACGCCAAGCGTCTGCCTCCCTCGGGGAAGTTATTAAGGCCTTATTAAATTGGTTCCTTTTCCCGTGGAAACTTTTTACCTGACAAAAAGCTCGGGGTAAGAGCGAGTAACAAAGTCAGCCTACGAGCGCTTTCTCCTCTCAGCGTGGATTTCTCCTTTCTGGCCCGACGACCGGCGTAAATTATTCCCTCGTTTTCGTCTACTGACGTGTAATTCTCCACCGACGACAAAATGACGGAGTTATATTTCCGGAAACCACGTCTTGCACGTAGAATTTAATGCTTGTACAGATACTCGATAAAAATGTGATTTCTTTTTAAAGTCGTTTTTCACCGGTACCTAGATTTCTTTTCTCTTTACAGCAACGTTACTAAATCGTATTATTCCATACGTCCTCTGATTACACGACCGTTTTATCTCGTTTAAATTTTATGACATTAATTTGGTTTACTTGTTATAATAAATATTTTGATTATTTATTTAAATTTCTAATACACTCGCAAATGAATTTTTGCCAAATGACACAATAGCAGTTGTAATTCGAAAAATTCTGTTAAAGGTATTTTAAGAAAATAAAGTTTAATAAAAGTAGAAAAATCACTTCCGCAGAGTTGTGAGCTAGTTAATTATACTATCCCATGGTAATGACTATGAATACTTCCCGCTAACTCTATTAAGATATTAAGCGCCCTCCTTAATACGTTGCAGGTATCTAATTACGAATCATTATACTTGAAGGAAGCTGAAAATACCTCCCGCGGGAGGAGCATGGGCAATCGCATTATGGAATCGAGGCCCATCGAACCTCGACGCATAATCCACTTTATCGCCGATTCGATTAATTCTCGACGGGATAAAACGGTGACGGCTACCCAACGTCTAACGAGAGCTTTAGGAGCTACCTAACGAACGATGTCACTTTTCCTGTTATCGTTGTCACTAGTTCTCATGGTTCTTTTGTCAGACGAGAGCGATGAACGTTATTATAACGAACAAACAATGTCATCGTTAGAATAGCACTGTAATAATTTAGCTTTTGCTTTCATATCATATGAAGATAGATGATTAAAATTACTTTCATTTCTTACAATAGGCGTTACAAATCTTTAATTTTGAACAGAATCTAATTAACATTATTTTTCTTTAAAATTATTTTTTGTCATAATCAGAGATGCTTTATTTTATCTTTTTTTTCTATAATAATCGAATGCGGATGCAATGAAAGTTTAAACCGCGCTGACCCTTCCTCGTTATTACTGCGATCATTCAAAATCGTCGACGACATCTCTCATAGCGAAATATCGTGGTTCATGAACCAAGCGCCAACTCGTAGAATAAGACAGAAACTTGGCGTGTGCCGTTTGCACGACGGATTTGCGCTTCTAGGAACGTTAATGTGGCCTTTCGCGGAGGACCCCGCCGTCTTATGTGGTGTTACGCTCAATTAAAATAGCGCGGCGTCTTCTCGGAAAGTAATAACGGCAATCGTTCGGGTAATCGTCTTGTATGAGGAACCTTTGCTCAGCGAACTGAATGGAGGAGTGTTTGAACGGTGTAAAGGATCGGTCGCCCGAAGCGACAGTTTACAATTCGTCGTTACAGCGGGACAAAATTTCGCAATATGTCGATGTTTATCGTATTTACTCTGTAAATATCCGTGTTGTTCGATCGACAAAGCCTCCGACGAGGAATATTTGCCAGTTGTCACCTAAAGTCGAGGGTAATTTACACATCTTCCTTAAAGTAAACAAGTGTTTGTGTCTCTACCTATGCAGGTAGTCATTTGAAATTAGTGTACGTAATTAGAACAATTAAGAACCATTGAGATCGCGAGTACCGAAAATCCATTTAGAATACAGCGATGCTTAAAATTGATAGTGTTGAATTGCTGAATGAGATGGGAATATGTTGACGATACGTCACAATACAAAGATCACTAATGAAATTTAAATAGACATGTAATTTAAATGTCTTCAATGGAATGAATTTTGAACCATTAAATGAAGAATACAAATTGTTGTCTCAAATTTGCGAACAGTGACGAGAGTAACATTCGTCATAGAGCTCAAATAGGATGAAAATGCGTGATGTAATTATGACGTAGAAAAATTTATTAGATAATTCTGATGGATCTACCGGTATACTTTCACAATTCAAACGGTAAACCTCGTTATTGATCCGATTCGATCGCTACAATGACGGCCATCGGAAGTCCAATAACATTCTAGAAGGCACAATTTTCATCTTGCACTTTTGCCAGGCGACTCACGTAGCGGCTAACAAAATTACATTTCGCGTCGTCGACCGGGACATCCGCTAAATACGTTTCCATGGGTTTTCGTGAAGGCGGGAACAGAAGGGGCGCGAGAATAGGAGGAAGGGTACTTGACGGTAGTAAATCTGATGGGACGGACGATGGTGAGAATCTGAAGGAAGAGAGAAGGGACAGTTGGGTGTGACGGGATTGGTAGACAAGGTCCAAGAATAAGGTGTTCGTGGTGCGTGTCTATATTTGAGTTGTGGCGGGATGAGAAAAGGGAGGGTAGGCTGCTGGCAGATGTAATCAAAGTTTGCAGACAACCACCCTGAACGAGAACCTCTGCGAGGAACACCAGGGTGGGGGGgAGGGGGAGAACACAGGGGATACCGCCGCGGGATCGGCCGGATATCCGGTCGTATCTCACACGCGGCGCCGCGTCGCGCGCTGCGGCGGCGTGTCGATACTCCTGCTTAATGTCGTAGAAATGTCTCCGGCGGAGATAAGGGAGAGAATCAAGTCGCGACAAGGTGAGACGTGTCTATGGGGAGTGGATCGTAGTCTGGCGCGAGTCTCGATTTTCTCGCGTGCGGAACTGTTCGTCCCGTCTTCTCGCGCCGGGGATCTGGGAATCGAATGATTTATGGGTAGTGATTATATTCAGACTTCGCGTGCGCTGGTATATCATGCTCCTGTACGTGTGACTGCTAGGAAATACCGCGACGTAATCCGCCATTTACTATATGCGCGCCGGATGTTTGGTAGATGTAAAGTAGTAATTTATCGATTGCAACGTGTATTGGGTGATCGATGATAGTTTGTCATAAAATTCATTAGTTTTCAATTTTAATCTATCTGATTTTAATTTGATCTAATTATCAATAATGTATGATATTTATATTAATAAAATGATTGACACGTTTGTTACTACGCATCATAAACATATGACTTATAATAAAATTCTGATTTAGAATATAAAATGTAAGATTTAGAAAAATGTTGAATACCTTTATTTTCAATACAGTTTTtCTATGTGTGCATATAATTGCACATGCATTACATTTAATAAAACTGCTTAAAAATGCAGAGTAGCCTCGTGATGAAGATTTTTCAAATTTAAACAAAAATATTAAGCTAAATACACTTGAGCTTCTTTTAAATTGTATCAATTATTCTCATTTCTAATAGAGCTAAATATATAAAAaTATTAGTGATAGAGGTGTTATGCATTCTTCCGATTATTTCATTGAAGTTGGCTCGACGCGATGCGATATAAAGTTCTCGCAGTTTACGCGCGATATGTTTCAGTTTGTTTATGTCATTTATAACTTTTCTACGGAGTTGCAAATCTGACTCGTAATAACGCACACCTTGCGACAATAATATCCGCTTGCAGGTCCCCCCGATTTATCTTGCCGGGAAAATATAGTCTTCGCCCGATAGATTGCATTCTAGATTTTCAGCGCATTCGTAGCGACGAAGTCGCAGATCCAGATAAGTCGAATATTGCATTTAGAGCGACTGTTCGTTTCTCTGCGATTGGACCTCTCTCCGCTCCAACACGAAAAAATTTTGAACGGAACGAAGAGCGGACAGCTGTACAGCGAAAATATTGTGTCAGATAAGAAAGAGAACTCTCTGCCGTTCTGGGCGAGAAAATATAGTCTTCTGCATGCTCGGCGCAGAAATGCAAATGGAATCTTTTAATTGAGTTTACCGGCGAGACATCGATTTAGTGTCTCTGGATCGGCAGAGTTAAAAAAAAAAAaaaTGGCCGAGGAACATTAAGTCTATTTGACGTATCGACAGCTTTTTCGACTCGCTATTCTCGAATAATTGTGGCAGGTGGAACGGAAAGAATGCGAACGACGCATGGTTTCCATTCCATAAGTGAACAGTTGGACAGCTTAGAGGAATTAGACATCATTTATCATTGAAATTTTATTGCTGTTATCTTCCACGTTTTGTTAAATTTAAACGTTTCAATATCATGAAAGGTAAACTTTTACATCCGTCCAATATAGACTTCCCGATATGCGAACGAAACAATTTCTATCACTGTTGTCTCGTTGGATAATAGACGACACAAACTTCTGCGCATATTACAGAACAATATAATAGTATAATTGTGAGTTGAAAATGAGGATCGTTGATTCATAGTATAATAGTTTGGCGAGGAAAGCGGATGGCATTTACTGACTGTCGTTTTGTGTTCCGTCCCAGAACAATGCAATTAACATGGTGTTTAAACTTAAGCTTTGGCCGCATTACCGTAGAAACTTATTGCGGCGAGGGAGGTTGAAGCGCAATAAACACACTCTGACTTCTGAAACATTCAGACGGAGATTCTACGCTGTAACGCAGCGTCGCCGGGACCGCGCTTTGAATTTATCGGGGCTGGCATGCCTCCAGATGAAACTTCTTTTTTGTCTCGTGCCGGCCGGTCATTTCTCACCTCGCGCCGTGCGCGTGTCAACCCAATAAAATCAAATATTAACGCCCGGATGTAAAATCGCGCTTGTATGCCCGTGTATTTACGGTGTGATACGGTGACGTACGAACCATGATGTATCGCGCGACATTTTATGCATGTGAAAATAAAACATCGTAAAGATGAAGGAACTGCCCAACGGACGGGAAATGCTCGGGAGCATGGAACTCGGGAATCAATAAAAACATGACATTTGTCGTTACGATATCGAGAGAGCGCTTCCTCATGAATTTCTTATGATTGCGCCGTAACGACAGCTGCGAGAAAGTCCATGAAGAAGGAAGAAATGTTTGCATGTCTTGAATCAAGCTGTTTCATGTCACATTATACCAAGAAATTAAAAAAATGAGTCGTTTTTTTCTTGTTTTACATGCAATATTCATTTTTCGAGAAAAAGATCAAATAACAAGTTTAATTGACATTTTAATTTTATTTTAAATTTTGTTATCTAATTTCAAGCTTTTAATTCAAAGCCTGTGTTCTGCGTTTTTAATTGGTTGTAAATTTGTTAATTTAACAATTGTTTAATCATGTAATTAGTATAAATATAATATTACATAAATGTTTTTATAATTGATATAAATTATTTTATTAAATTTATGTAATCTAATATTTATTATATTAATAATTGTAGAATTATTTAATTAATATAAATATTTATTAAATTTGTAAAAGAACTGCTGTTGAAAAAAAGGCGCCATTATATTCCAGTAATTATAAATTTTGAACAAGATTTAAAGATGTTAATCTTTTACATTAGTATATCTTCTATGATGCAATATCAGTATTTGCATTATGTCGTATAAATTCAATTAGTTTCAAATTATTATGTATACTGCACAATTGTAAAATAAGATAAGTATCGTATTATTTAAATTGTTCGCTCTTTAATTCAGTATTTCCGTGGTCAATAGCATCACTTCACGCCCGTGACACTGATTTACAAACGATCATTGTCTTCAACAAGGGAATCATTCGATTCGTCTCTGAGCAGCGCCATTCAAAGCGAATGCCCATGTTTCTTAGACGCAGTTCAGAGCAGCAATAACAATCGCTGTTTGTGGCGCGGGAACGCGGCCGGTCACTAATTCGCCGCATGCATTTTAGCATTTCTCTACCAGCTGCGTGCGACGGCCTGTTCGCGTACACTTAACAACGAAATCGATGCTAAACATCCCTATGTTATGTACATAAGCGAAACGGCGGAGGAGGCGCCAAACTATTGTTCCGCCGTACGGTACGATTCGTTTGTCGACGCAAGTAGTTCAGCAAAGATAAATGCGGGGTCACGTGTAAAGGAGCTACGTGAACTGACCTAAAACATCGCGAAGAAAAGCACCTTAGAGTTTTGCACTAAACGTGGTAATTGATCGATCGATTTGTTATTTGGGCGgTATATATATCTTTTTAATTTGTTTTTTtGTATTCGGACAAAAAATAGCTAAATAATTTGTCAAAAATTATGAATATTTTTCTCATTTAAATTGCAGGAAACAAGTATTATTTTGTTTACGTAGAGTTAAATAAATTTCAAAATTGTAAATTATAAATAATTACAATTACAATCTTCAAATATGCCTTGCAAATGTAGCATGCGCGTTATAAAATATGCAAATGTATTATTTATCCATTAATTTTGAGGCTGTAGAATACGTTATTATGATTGCATTTTGCATCGGTGCATTATTTTTAATGATTTGACATCTTTCTTCTACAAGAGTTAGTTATTACAATGAAAAATGCGGCAATCCAAGGCAAATTTTTTTtCCGATTATTTACAACATTTGACGTTCTGTAAATGACAAGGTGTACTTTGCGACCGCCAAGGTACTCGCGCCCcATTATTTTAAGTGGCGATGCCTGTAATGTAACCGAGAGCAGTAAAATATCGTTTCGCCCGGAGGATATATTACACTTTTAAGAATTTCCGACGGTGTGGGTGGTTCGTTAGCGGGTGTAACTAGTCAAGCAAAAATAAATATTCGCCCACGTAGCGGCGGCGCAACACAGTCCAACCCAAAGTACGGAGCATGGAAATAACCCCGGAGCCTTTTTACAATTTAGATAAGCGTCCGCGCCCTCGCGTATATTCGAATCGCCGATCAGCCGTAGATCAAGCTATCCGCAACTAAAATTTATCCAACAACGTTAGGTATTACGTATATTGCCTCATAAATATTCAGCATGAAAAACGTGAGCGGTTATTTCATCATAAAATTAGCGAAGTCAATCTGTACGGGTAGCCTTCGTTGACACGTTTTAAAAACGAATGTGGAGCATCGGTCAGATTCTTCAACCGTATATACGATAAATTTATATTACACTTTGATTTTTTAGTATAAATATACGAACAAATTTCAGACATTTTAAAAAATGTCTGAAAATACTTTTACAACACAAAAACGATTTACTCACAAAAAGAGAACAATTTTACTGCAGTATTAAAAAATTTACCTATAGAGCAGAAGATAATTTTATGTTGGGCCTTCAAAATAATTATGTAGGACGCTCAAATATGACAATATTGCTGCAAACAGTTTTGACATTTTAGCAATTAACAATAAGTTAAATATGTAATTTTTTGATTGGCTCAACATGATTATTTTCAAATCTGTATTTCAGCAAAATTGTTCCTTTCGTGCTAAAGTATTTAAAAATTTAGCTAGACACAAATTTAAAAATAATTTCGTTGGATTATGAAGACAATTATGAAGGGCGTTCAAACATGATGCTGCAGAAAACTTCAAAATTTTCAACCAGTTTGAGTATCCTATATTTAATTAAATTTTTAGATACTTCAGCAAAATTTTTTTTTtCTGCAGGTATCAAGCGATAATGGAAATAATCTTGTTTTAATTTGTTTGCAATAAACAATATAAATTAGAATTGCTAGTTTTAAAAATAAATTTCTTGCGCATAGATAATTTTTTAGTGGGATAACAAaTAAAAAAaCAAGCTTACACGTTATCGCGTTGAGGCAACTTACAGAAATTCGCTTACTTTTTCCTTGGCAAATAAAGTATTGGTGTTGCAGCGATTAATATGTGCATCTCGTTAACAGACGTAGGGTTAGTATATGAAGCAGTTAAATTAATTGGTGATAAAATATTCGGACAATGTTATGCGATACGTCGCGTATCCGTCCTAATATCACTTTGGCGACCTCGGAGCGGCCCAAAGCGGCAATTTGTAACGTTTTATCCAGCGGAAACGCATGCATCTCCCTCAAGATTTCCTGACAGTCGTACACTGGCCGGTGCAACTGGTTCAGAAAAGACAAATGCGCCGGTTACGTATAACGACCGACGTGGACTCGCCATAATACGGGAGGGAAACGATGTCGAGTCCCTTAGATTTCAGATAGTCCTTGTAGCCGCGTGATTTTTCTGTGTTCTTACCCTCCAAGTGGACCGACCCCATATCGCGAGAACATCAAGTGAGCGCGATGACCCACGCGAGCTTTATCGCGATAGCGTGCATCTCACGAGCCGGGCATCCTCCCGCGCGCTGTAAAACAGGACGTACCGAGCGTCTATTACGCTCATCGTGTAATTCAGGGACGCGGCGGAATGCGTTAAGTGCTCAAGGCGCGAGATGAAATCTCTGTTTCGTGTACCGACCAAATGCAAGAATGCCTCTGCCGTGTGTTACAGTAACAATTACAAACGAGAGGGGgAAAGGAGATATGTGATAATTGTTGAGAGAGCACAGTTCCTCTTCCCGCATAAACGTATTATTCGTTTCATTATTTATTCATTTAAAAAaTATAAAATATTAATTAAACATAACAGTTGCCTCTATTTCATAAAAaTTTTTTtAATATTTAATGAGATCAAACATTTAAATAATAATTCTCTTATAAAGATTATATTTAATATTTAATTATAAAATTTAAACATCTATATCATTTACACGGTAGCTGAAAGAGATTTTATTCGTTGCACAAAGGTTTCGATCCGTTATATATTTTCGTATCAGATTTTAAGCATAGTATAATTTAATCTACTATAAATAGAATAATTTTCGAAATATAAGTGATCGAAGTTGGTTAACGTGATATAATGGAATTAGATCTAATAGAACATTTTTTTTCTCGATAAAATTTAAATTTCTGAGATTTTAATAAATCTGGAAAAAAAGTGAAGAATATTAAATTGCTACATAGTTTGTGAAAATTTAATTCTAAATTTTTAAATTGCTTAAGAGAATTAAGAACTAAATTTATTAATATCACACAATTTTACTGCTTGTAATAAAACAGAGAATTCAAGTAAGATCAATAATGAAAATTATATAATATATTGCTTCAAAAATATGTTTATTATTGACATATTGATTTATAAATATTTTATCAAATGTAATTTATACACTCAGAGAAAAGTTTCTTTGATTAAAAAAATATTTGTTTGAATCAAGAAAATTGGTGCATTATTATACGGTTAAAAAAAAGATTGATTAAAAAAAAaTTTATTGATTTGAAGAAATTTCTTGATTGTTTCTTTTTATTAGAATTAAAGAAATAGTTTGATTATGTAACGCAAATCTTTTTTTTAAATAACTAAAATAAGTAAATTATTTCTTACATTTGTTAGTACTTTCTTTTTGAATAAAAAAATTATTTGTTTAAATTAAACAAATAATTTATTTACGTTAAAGAAGGATAATGTCATTTCTTGAAATTAAATAAATTTCTATTTTCCTCAAAGGTATTTTCACTTCAACTTATTAAAATAAAATTAAGGAAACAAATTTTTAAATTTAAACTATAACTTTTCTCTGGATATAACTATTCTGTTCAATGCGCATTAATCATTCGTTAAATTGTTTTGTAATGCAAAGAACATTACACACAGTCATAATTTACTTATAATGCTACAAATATTTCGTGTAGTGTCGTGGCGAATTACCGACACGCGGGCGTTTGTATTTTGCCGCCCACGGTGTAGAGTGTAGCCAAGTGTAGGTGAGTGCGCGCAGAGTGTAAATATGGCCGCCATTCGTGCGGCGAGATTCGAGCGGGCGACCGGCAACACGAGCCGCTTCGCGTTTCGCATCGAATTCATCCCTCGAAATGTGGCCGTTCCTCGCGAGCGATTGGTAACTATCGACACACATATGATTAGCTGTCTTCCGCAATCGCGGCTTGTAAGCGATCCGAAGCGACGACTGCTTGTCGAAAGGTATTTCGCGCGTTCGCTCACTTGAGAGTGAAAAGCACGTACAGTCACGCTTTAGAGACTTTCAATCTAACGCTCGTAATCTGCTCGCCTCATCAAAAAGCGCGGGTGGACACGAGAGAAGCCGCGATATACATCCACCGTTTACCATAGGGATCAATCTAGCGCGTAAAGTTATTCGGCGTATGTTTACGATATCGTGATATTGGCTAACGTCCGGCGCTTGTTGTTGTCGGCCGGCGCGGCGCGGCGCGGCGCGACGCGACGCGACGTACCGATACCGATGTTTACAGAAGTCGTCGCGCGGCGAAGGCCGAATAGACAACGGCGCAGAGCGCCGACGACGTGCGTCGCATTATCCTTCGAGGCACGGATGCGTAGGGGCGACGGACAGCAGCGATGGAAAACGCGTAATTCCTCTCGCGATCGATGCCACAATCGCCGAACATCGCGCGATAAGTCAGCTCTGACAATAACCTCGCAAACGGCCCGGCCGGCCGACAACAACAGCGTATTGACGGCTGTTGATATGCGATGGCGATACAATTAGTCTCTCTCAATGCCGGAATCGGAATGTGTATCTCGAATCACGCGCGGTTCAATATTTCGATCGATTTTCCTATAATTCGCACGTCATTCTCGTGACGCGCAAATTGCCGGATGTAAGTTACGGTAATATATGTATCAACTGTTTAGATGTTAATCTGTTTCGTCGGGATTCGTATACGTCCGGGAATGTATTGCGCGGCGTGTGTAATATCGAGTTTGCATCGTACGCATTGTCCGTCATGTCTTAATTAGCAATTACGTTGATTTTAACGGCTGGCATCGCACGTAAAAGTGAGTTCGCTGGCGCCCGGCAATTAATATGGGCAGAATTACCGCGCGATTATCTTCCTCGATTGCACCCTGATAATTAATTCGCGCGCGATCGTAGTTAACGCGCGTTTTCGCGAGTGCTGTATTGTGTTGTGTGAATGCGGTGAACCTGGCAATCCTGGCAACCTGAGGGCAGGAGAAGGAGAAGGAGGAGGAGGAGGAGGAGGAGGAGGAAACGTCGATCCTGGAAGGCATCGTGCGACTATGGAGCAACCATCGAGTAAGTACGCATATATAATTTATTATTCATGTAATATTGTGTATCTGTCGTGAAATGTTTCTTTCCATTTGTAAAGGGTGTTTCATGTGGGCATAATTCTTTTTCTCGGGACTGGATAATAATTAGTTAAGAGTTAAAAGTTAAATAATTAAGTTAATAACTTTGAACTTAACTTAGTTAATTTTAAGTAATTTATTTTTTtAACTTTAATTAGCTATTTTTAAAACGCATAAACTTCAATTTATTAACTTTTTTCCTGGGTTAAAAATGTATTTATTATAAAAGGAAAATTAAAAGAAAAAATATATTCCCACGTAAAAAACAATATTTTTTTAATTATTTGAAATAAACTTACAAATTAATTTACAAATAAAAAATGTGTTTGTTTGATTTTAGAAAGTAATAAATTTCCAATTTATGAATAATTTAATTTTTACAAATTTTTTTTtGTAAAGATTATGCGATGGATCAATTTCAAATTTTGTGTATTTTATGTAATTTCAACAATGTGAAAAATAAAAATTATTAAAAATTATTAATTTGTTTAAAAGATATAAAATAATGAAGAAAGCGCTTCTAAAAAAACTTTGTTTTTGGTGTGCACGATAGGCTGATGAACTGAAACAAAAGACTCAAACTGCATTTTATTTATTAAAAATGGGTAGAGAATAAACCTGGATTTTCTGGAAAAAAAATTGTAAAATGACGTTGGTTTAAAGCTAACATTGTGTATTTTCGTTAAAAAATCAGCTTTTACCGCAGCAAAAAAaTATTTGTTTTTAAAAATACAATTCAGCCGCGAATTGACTTACAGCGAATATACTATAAACCTTTTGCGTTATTTTTATGTTCTGAATTCATATTTCTCAAGTTATGCCCACATGTTATGAAACTCTGTATATTTAAGTCATTTACGATTTAAATGACAGAATGTGCGAAACATTTTAATTTTTCCGTAATTACATAAAAGCTTGAATGGAAGGATAAAATTATGTGACTGTTTAATTAAATTGATCCACTTGGTGGAATATAAAAATCGATGTGTGCTTACGAGATTAATATCCATGATTAAACTCTAGACTGAAAATTTATATCTATGTACAGTACATTTTAAACTCTTTTTAAATTATGCAGAAATGTCGTCATATTTGATTATAGCGCAATAAAACGTTAAGGGAAGGGGAATGTAGTGAGTTTTATTTAAAAGGAAATCTCTTTTTATATCCACTATATTACAGCATAAAATCGGACTTGGGTATATTACGTTTGAATTGTATAATAAAATGCGCGGCGATGTGAAATGCACGGTCCACCTACGCGCGGACGAGAAATTTCTCAGGCTAACTTGCATAATCGCGGCAGGGATAGCACGCGGCGGATTGAGGAGCGGTCGGTTAAATCGTCCGTGTGGCGAAACACCGTTTAGCTCGGACGCGATCTTCCGAAAGAAACAGGAAAAATAATTAAGAACTTTGGAGCGCGGAGATCAAAGGGCCAAGTTCGTTAGACGAGACCTCGACGGTACTTTTACATCCGCGCGCAATCAGCGGATCGCCGAGCGCGGCATTGTAATCAAGATAATTAAACAACGCCGTCCGTTCTCCGCGGCCTCGCTGAAATATTAAAATCGTTCGAGAGTTCGCTCTCTCTTTCTCCCCCACCACTTTCCCTGCCCGGCTTCAGAGCTCTGCGTTATACTGCTTTTAATTCTCGATAAACAGTTCGTCGCTCTTTTTTtCGGGATGTAATTATATTGATCTTCTTCGAGGATTTGCGAATATCCTTTCGCGTTTGCCGCCTTAGTGCGCATTGAAGTGCGTTCGTAACCCTTTCGTTACAGTTTGCGAAACACCATCTGGCGTGTGGGTCACATATCGTACTAATTTTTCGGTTCTAACCATTCTCAAGTCGTTTATTTCTTGATATATTGATGTTTGATGATATATTTTTCTGTTTAAAAATAAAAATCTGAAAATTGGTGAAAATATATATATTAAATTCTCGGAATTATTTCTTTTTCTAAAGTCCATTTATAATACAATAAAAATAAAAATTTTCAAGAAATGACTTGAGAAATATTTCATCTTTTTATTTTAAGCGCGTATATTTAATAATCATTTTAATGTTTACGCCATTCCATTAAGATATAAAACATATTTTATTCAATGACATAACAAATTAAGACTGGTGAAATTTACGCAAGATAGTTTTAAGTTCCATTACGGACTAATGTAACTGGAAACATAAATTCTCGTTTATAGTTATGAAATACCATGACATGTCCGTCAGCGTTGTGCTCACGTAGAATACCGTTAATTGCAATTTATATAGCTGCGTCAGGTGAATCGTTACTCAATAAAAACATGTGCTTTTCCCACATCTGTGAATAAATGACGAAAACGATTGAGAAATCTAGTCTCCATTAAACGTTACAAGCGCAACTTGTCATGTTCTGGACAAAAGCATGCAAACATGCATGTTtCCGTTTTTTTTttAAACATAAATAGGATTCAGTTGCACATATCACGGATTATTCGAAATATTGGTATTGAACTATCAATTGGTACCTCTTAAAAATCTGTTATTTTATTTTAATATTTTTtAATATAATTCCGATTTTCACGAGAAACTCTAATATACGAGAGATATTTTTGTATGAGATTAAATTAGGACGTCGAATGGAAGCCACTCGGAATATTGTTAAAGCTTTGCCGTTGATATAATGGTATTTAAAGCAAATAGATATAGCTAAAGAATGCACTCTTTGTTATTGATTTGAAAAAaTTTAATTTGGCAACATGATCACAAATAAAGGACGTTGTTGATCAAAGAGAAATTAACAAAAATTCTATTAAAAGGAGATTGGAAAATTATTACCACATCATAAAAAAAACTATATAGATTATAATAGTTGTTATTTTTAAATTAAATTATATTTAGATGAAACTATTATCGATAACAAATAAGTTCAATTAGAATTATTGTAATTTTGTTAACAAATTAATATTTGGTAATCAAATTTAGAAAGAGCCGTACCATATCGTAGCAACAGAAACATAATTACTTACAACATCGAAAATATGCATCATTTTATATCGCGAATAAATTACTTTTTGAAAACAATATTGATAAAATATTTAATTTAAAATTGGCATCGACCATTATATCTTCTTGCAAATTTTACAAACGCAACAAATGATTTTTTAACTTTTGTTGTAAATAAAAATCGCCGTGCGATATTGATGTTGAAATATAGTGGTTGTGCAATGGTAACCATTTTTTTtGTTCTTCCCAACGTGCGCGCAGCAATTAACGAAAAACTTCTCGAGGCGGAAGTGCCTGTCAGAGTCGTGCATTTTAGCGCTTCTGTTCGTGCTATTTTTTTtCCGCATGGAAGAGCGCCTGGGAAAAAAaTGCTTTTGCCTTTACGTCATTTTTTCGTTTCTGCTCTTTCGTCGTCACGTTCTTCGTTAATCACGTCATACCGTCAGTCTACGTACTCATTATAAACGCGCACGCTGTTATGCTCGACTTTCTTGATTACAACGTCAAAATGCAATGCCTTTATAATTTTTTTTtGCTTTAACATAATAGAGCTGCATAGTGTAGTTTTAATGGTTATTGCGACTTTCCAAAATTTAATTTTAAATTTTATACTTTTTGTATTGTAAAATTTATATACAGTGTGAGAGAAATTTACGAAAGTCACATACATTAGATTATGTACGTGACTTTCGCGATTTTTTAGTGTATTTTTTCTAAAGTAAAAGAGAAAAGTAAAATGAAAAAAAAATTACCTCGCAAATAATGGTTTTAACAAATATTTGCGATTTATTATCTTCACTTTACCTTTATCGGCTTATTAAATTATTGTACACAACACGTATGTACGTGTGTGCGTATGTGTGCGCGCGCGTGGAGAGTAAAAGGTAATTAACGTCCGGAAAAAATTACAATAAAATACGAATGTGTAGCCCGTTACGTGTATAAATTCCCAGACGCTTTCGGCCCGGCTGTATATTTGCGAGGTAAATCACGGACGATGTACATTGCTCGTCGAGGATGAAGTTACACGCATACTCACGCGTTTGGACACGAGCGTAGCGCGCACGTAACGCCGCGAGCGAAACTTGAAAGGGTGCGTGTTCGTTGCATAGAAACAAAGGGAAAGAGAAAGAGAGAGTGCACGATGTGCTTTCATGCTTGGAAATCAGGCGTCTAAATCTAAACGGCGCCGCGACACGACGTCCCCCTCCCCCCTCTCTCTCTCTTTCCCTCTCTCTTCTTGAGCGTCGACTAATTACCGTTAACGCGAGCCGCTTAATTAGCGTCAACGTTAATGCCTCACCACTGACTCGCGATGGAAACTGCGAAACCCGCTTCAAGGCGCGACGGATCGCTGTCTGCACCGCTCGAGAATTTATTTCGTCGACGTTGAAATCAGAATCCAAACGGAAACGTCGGGAAAATGAACGAAAGATCGAAAGATTTCAATACATATCGATTTAAAAGTTCGTGTCGGGCTTGTGTAAGTCACGTAAGTCATTATGAAACGCACGTTATAGCGAAGCTCACGCACTCCGTCGAATGATTTCGACGAATATGCAGAACACGTCACGCAAATCATAACTGCGAAATATTTAGACATATTTTTTGAAAAGAATGCTGAACGGGGGTAGAAGGCAGGAAAGCACAATCCAATTGGTTACGTGAGCAGCGGGATTATTTCGCCAGTCGATTTCGCGATAAACCAAAAATTCAGCTCGCGAATAATTGAAACGCAGCGTCGAAGGCTTATGTATTTTTATGTTGTTAACGGCACCCGGGCAAAATTCCGCGCGCGAAGAAGCGTAGAGGGAAAATACCCAGGATCAGTCAATAAATATGGACGTATCGGATTTTTGTACATTTTCGCGTGGGGAAAATCCGCTACCTCTGAAAATAAAAGGAGTGACAATGCCAGATTTTTGCCGGAGGTTACGATGGATTTGTGTTTCAATTTAAAGTTGAAATTTCAATTTAGATGCCTGCGTATTGCCCGCAATAACGATACATTGCAACCTCGCGGTGTTGTCCTCTCGATATGTAAGGCAAATCGAACACAAAGTTTATCGCTTGGTATTGGCATCCTGTATTTTCAGAGAAATCTCCTGTAATATCGATCTGGTAACAAATTGAATAAATAATTCTACAACTCGGTACTCGTTGGCACGTTGGTACTACCCTTAGAGTACACGATATATTTTCGTATCGCATACCTTTCAGACTTACGTCTTTTTCCTTCTGCGTTTCGCACGAAATCCACGGGTATAACGTCATAATCCTTTCGCGTACAATTGTGTGTACAATTTGAACAAGAAGGCGAAGCTTACGTGCCTGAGTGTAATCAAAGTCAGTATTGTAGAGGATTCAGTAATTAAGGAAAATCGCCCCCTACTACTTGAAATGCATGCTCATGTAATTGAGCGTACGTTCGCGTTTTTCTCTCGTCATGTGACGTTTCACGAGCGTTATCAAGATGTTTTTCCAACATGAAACAAGGATTAATGTCCTTCACACTATATGAAAGGCTAAACCCAGAAAAATGATATATCTTTTCAAAAGAGAATCCTTCAGCTCTCTTTGAATAACATTAATGGGTTTAATAATATTCATTTTtATATAGTCTAATAATAAATTGTTTTTtGCTACGGGAAAATTTTCATGTAATATTATATTAAATAACCAAAAAGTATGGAAAGATTTTAAAATTAATTTTTAATTTTtGAGATTATACAAGTCTTTCAATAATCACATAATTTATTGTGGGTTATACATAATTATTAAAATATTATGAATATATTAGCGTTATAGATAAATATTTTGTTAATTATGATTCTTTTGTGAATAATATGAATAAATTTTGTGACTTCGTTTGATGATAAAATAGTGTAAAGAATTTTTACATATGAATAGAACGTTTATAAACATGTGCAGTAATTCCGCGCGATTTGCTGCAAATTAATAGTTTTAATTAACACTTAATTTATTTTCGAGATAGAAAAAATTCATAAATTATTAGTACTTGATTTGGAAAACGTTTTTGATAATCATTATCCGCGAGTCGAGTTGTATTTCATCCTACAATTCGTCGAATCATTATAAAAAAaTTGTAGATGCAATCTACTTGTAGATGTTTAGACTTACATGACACAGAAAAAATCAAGTTTTACTTTTAAAAATGATATAAGAAAGAGAAATAACTACTTTTTCTAATTACTATTAGCGTTAATATCGCATCGCAACTTTCTACAAAAATATAAGCAAAAAAGAGTAAGATATTTCCATATTATGTATAAAAAATTCTCATGACTGTAAAAATGATTAACGCAAAAATTTTTTACTCCATTTTAGAAAACTGTGATTTAAAGATAACTGAGAATATGCTTGTAATAGCAGATTTAAATTTTTtATACAATTCAGAAATTCATTAATATTTTTTTtAATCTTTAGTAATAACTTATATTAAATCTAAAAATCTGGATCTATATTGTATAATAATTGATACATATAAAATCATATATTTCTAACACTAAATGGGTGTAGTGCAATAATTCATATAATATATGCAATCATATTATGAAGAAATATTGATCCTTTTAATAACTAGGTGGCCTAAATTCGAATAGTAATAATTTGATCATAAAGTAACGTGCATTCACTAACAATAAGTGCAATGTCGAATGTTGACTTAACAAAGCTCAAAAGTGTAAAGTCATTCGTTAGATTGCGGATGATGCGCATTGCACTATTAATAGCTATATATATCGCTCGTATATTTCATGTAAATAAATCCTTAGTGACCCGCGCTTATAATATCGCGATTATCGCACTATAGTGAAAATGGTAATACCATGTTTTCGTAACATATGCGATGCAGTTCCCTAATACGTTTAACGCATTATCATAAATATCATCACGACCGATTACATGATTGCAGTCGAATATTCGTTGTTGATGACCGCGGGCACTTTACAATTTAGCATGACATTTATTTCAGCATTTATGTTCATTTACGTATGCCTATCTTTTATAAACAACGCGTTTATGACGCACACTTCATATAATTGCATAATCCCAAAAGTTTAATTTGGGATTCTACAATATCTTTATACATATAAAGGAATTTATGACGTTATAAATTTTAATAATTGTTGCTTCAAAGCGCTGATTTATTCGACCAATTTGCGAGTGGTATTTAATTATTACGACCAAGCGATACATAATCGTGTGTAAGACTAGAAACATTGCGCAAGAGAAAAGCACGACGGGTAAATATGCTTTGATCGTGTCGCGGTTCAAACATTTGGGACGGTATTTGTGCACAAAGCGACAGAGAGCGAGGCGGTCGAAGCGTGTACAATACACCTATTTTTCGCGCTGTTCACACCATTGATCACTCTTTTCCTCTAACGCGTATATATGCGATCGAATAAACTACACCGCTCATTTTATGTTTGTTTTGTCACGCGATATCGTGTCATCAGCTCGTCTAACTGCTATTTTAGTGAACCTATGTAATGCGTAATACATAATAAAACGACCTGAATCTCTATCGATGAATTAAAAATGTTAAAAGGCATTTCGAGTTACGTTAATTCATTACTGTTGTAGACGATTGCTACCATAGAGCTGACACTTGACAGGCCACTTTATTTTAAAGATTTGATATGCCTTACGGCGTTGATAACACGAAAAGAACGATTTCGTTAGATCAAAAAGTAATTTTATTGGACCATCAAAATAATTACGTTCAAGCATGTTCAGCAATGCTGTAAAATGTTTTGACATGTCCACCAACCAGCTTTAGTGGTTCAGCATAATTATTTTGATGACATAACAAACTTATTTTCAGCTAAATTTTTAACTAACTTCAGCAAAGCCGTCTTTTTCGTGAACACAAATCCTTTTTTAGGCGTGACATTTGCACCGAACTGTTTCTACATTTGTCTAGCACATCCATATTTATTTGAGAATACCATAAATTACACGTACTATCATAAAGAGAAGATAATAGCTGAAATACGGAACAGTTATTAACCAAATGCAATAAGCAGCGCATTGTCCTTGGTAACCAAGTTTTAGTGGTTCTGCTATACAATGTTCTCCGCAACTTGGTTGATATGTATTTCGCACGGGCGCCATTATTGAAATTGCGGTTTAATCCCGCATACCGCATTACATGACGCATATCGCGAAAATTGAATTACGAGAAGAAAAAATGTACATTCACATTATAAATATACATGAATATATATTGTGCGGTTTGCTGTTCATTCGCTAGCAAATGCTAGATGCCGCATCGTTTTGTTATCGCTTTTAATTTTAAACTTCACCGTTTCGGAAGTTTTAAAGCGGATTTCGCGATTTATGAGTTTACGCGTACGCACCGGGCATGGTTCTCTGTACACGAGTCACACGGGTAACAGGTACACATTTTATCACTGCACGGCGGGAAATAAATTCCACGGCACGCAACAGGAAAATTTGGCTTTTTAAATGCGTCAAGTATTTATGGTTAATAAAATTTTCCGGACTGCCGGGCCTCTCCGCGCGCATGTGCGCGTGCGCGCACGCGAGTGCGACTTGCCTGCATTTTTCATTTTACGCGCGTTACTACCGAAGCGCGTCACTCTATTAATTCCGGTCCTTTGTGCGCGACGGATCATTTGTTTGCTACTCGTGTAATTAAAGTAAACGAGTCGTCGGCTGCACGCGTCGGGCCGATGGCGAGACGGGAGTCGGAATAGGGCGACGCCCGTTGTTTCCTCCCGAGAAATCGCGAGCGCTAACGAGCCGGGAATGTCTTCAATAAATATCAACGTTTTAATTAACATAATGCGGCGGCTTTATTGCCCGACATTTATCGCTGTCGCGTAACTCTCGTGCACAGGCGAAACACGTCGCGCTTTAATTGCACGATGCCATTATAAAAGCCGCCGTCGTAATATAATGCAAGCGAGACTATCGGCTGATAGCGAAGGTTCGAAAATACCTGCGAAGAACCGATCGTAAAAGAGCCGGTTCGCACTTCTTTTACCTTTCTTGTGTCTGTCGAACCAATTTTGCTTCAAAATCGGTCAAAAGTTGCACTGAGAGAAAAaaaTCATTGCAATTATTATAATTTAATTATAATTTCTAATTATTTTtCGTTTTAACTATATGTAATTATAGCTACAAATGCTAAACACTTTTTTtCAGTATAGTTACTTTTGTAGCGAGGAAAAAaTTaTGAAAATtCATATCTGTGCAAAAaTCTTAACATAAATTTtAAATATATATATATATATNNNNNNNNNNNNNNNNNNNNATCAATTTATACGTGTATCTGAAGCGAATACAATTGAAAGcTGATGATTTGTGAAGAATATTATTCTTAATTTtGCCTTATTGTCCACGCAAAAATAAAACATATCGAAGAAATGCAATGGCTCTTTACGTTCACAATAGGTTGCAATTTGCGTTGTAAAAGGTACAAAGTGAGGGCGTCCATTAGTAACATTAAGAAGTATTTCGGTCTCATCTAGCCGTTTCCCGCTAATGGATTCATAATCTTAATACTACTGAGCTCGAGTAAGCTCGCGTGTCTATGCTCGATATTACTTTACCGCGGCGGTCTCTTTCCATCCGTTTTTTCTTACCCTCGCGCGAGTTTCAACCTTTCCCTTCGTCGCTTTAAGATACTGCTGGGAATTAATCGCGATGGACCGAGCACTCACGTCCAACGATGGATAAAACCTTTTTCCGCGCGCGTGACGCGACTGTTACCATTGGCTCGAATCCACTCGTAACGAATGTTCCGGAATTAATAATACATGCACACGTAGCTCCACCAGCATGAAAAGTCAAGGGAGAACGCAGAAAAGCCATCCATTTCGAACCCTCTTGAGTATAGTGGATTTTCATAACGCGGAAAGACGGGAGTGTCTCCAAAACCGTTAATGAAAACTATTGAACATATCTATTAATAACAAAATGTCTCTAATTATCAATTAATAATAAAATGTGTTAAGTACAACGTGAGCTATTCAACATTAGACAAATAATAAATGTAATGAAAAAATATTGTTAAAAATTAAATTCATAAATTCATAAATATTTAATGTTTAAGAAACAGTGATAAAAATAATCAAGAATAAATAAGAAATTATCCGCTTTTtTTCGTAACATATAAAACTGTGATATCGCGTCTATTTCCATCTTTTCAATCTTTATACGTACGTTTATAAAGAATTTTCATTTTCCACGAACTTCAATCCGTCATGCATGGATATTGCGAGGACGGAGTCGATTAAAGGTTTTACACCATCCTGTATGCAATAAACCCCGCAATATCGAATTGATATTAATTAGCCGCGAGGAAGTACCATAAAGACATTACGACGGTGCACCGCGAACCCGCGAGTAATTATTAGCGATTTAATGCTCCATCGACCGAGAACCCCATAGAATACCGGCGTGTATGGTGCGCGAGAGCTATTGTCTCTCAGCAACGGAAGCTGTATGAGAACATCGTTGCATGCTTTATCACCGTTTTTTATGCTCTTTTCCTTTCGCCAAATTGCATTCGCCATACATTATTCTGATGGGCAGTACCGGCATGCGGCATCGATTTCGCTGCAACATCCTGCGGATTGAAAATTTCTCGATCGAACCTTTTTGCGTTTAATAATTTTGTCGCGAAATATTAGCGTTGCTGAAATTCTTCAAGTTCTATCAGTGCTTGTACCTCAACGAACAGATTGCGATGTTAGATGGAATTTCCGTCGAGCCGTGTTCGATATTAATCACGAAAGATCGCGCGAGTCTCTTACGTAAATACTTTTGCTTCTACCATTTTTTTGCAAAATGTTCTAATAAAATTCTATAAAAATTATTTAAATAAACTTGTATGAATACGATTCGTGATATTGACGTTGAAAAATCTAGCATTGAATTGCGTAACTATAAAAGTTAACACTGAATTAGTTTCCTCTTTATAATACTTATTCAGGAATATTTCTTCATATTCGTGAGGCAGCAGCTAAATTTGATGAGTCTCATTAGACAATTGCATGCAAAGTTTGGACAAGATTTTAAATTTTtATTTCCTCCAATCTGATCCAAATTGCATCTCTGTAAAGTACTTAATTTATTTTTGATAGAAAAaTAAGCTATGTAATAGCTATGAGTATTATACAACGTTAAATATCAAATAGCAAATAAGTTGCATGAGTCAAAATAAAAATAAATATTTTCTAGTAAAAGGCAAAAATTTTATAACTTATATTATACGTTTTTTGATTTTATTAAATATTAAATATTTTTTGTTTTtGAAATCAAAAAATAATGTTGTTTTTTAAAAAAACATTAATATTATATAATATATTGACAAAGGAAATAATAAATCATTGAAACTCTTTGCTCCAAAAAATTCATAAAATTGGTAAAATAATATATATTTGTTTCAAAATCTATGTAATATGACCTATAACAATCAATAACTCCTATTAATAAAGTTTTCTCCAGAAATGTAATTTACGCTAAATCCACAAACGTCATAAAAAGCCACCGTTTTGCATCCGCTTTTTATCATCGGTCGCGTAATTATGGTAACAGAGCCAGCGGGCAGTCCATTAGCCGTAATAATTCCATAAAATCTGCTTCGCTAGCGCGAAAAAAAGTAGAGTCCTGCTCGTTGCGGGTTTTATCGCCGGCTGTTTTCTGCCTCTTTTCTTCTTTTTTTCGGACCCCCCTTTTCGTCCACGTCGAGAAATTCGCGACCGGCATATCGCGCTCTTGTATCAACCGTGACGCACTGGTTTTATGGTGTCTGTTAAAATAGACAGTGGCTGTTACGCCATGCTGGTGCCTGTAGTCGCATTTACGCTATGGCACGTGAAAATCCGATATCTGTATACGTTTGCACTTGAATCATATGTGCAGATCGGCTCACTGTGCGTGCACCGCAGACTTTGATAAGAGTTATGCGCCATGCGTACGTCTTTTGTCAAATTCGCTTCCGTCTTTCCGTCGCTAATATCAAAAATAACGTTTCAAGTTTAATGGGATGTGATGTGGAAATAATATTGTCGGGTATATTCACACTTTGTAATCCAACGTTTTTTTCCCTGTTTTCTTAGTTCAACGGATGTCTGATAGTGTCTTTGAAAAGGTTTTTGAGTTCTCAAAAATCTAAAAAAATTCTGATACGTTCTACCAACATTCCAGAATACGATTTCACAATTGTTTAACTCAAAACGTTTTTCACTTTTTCTGTGCGTTTGAAGTTAAAGCAAAATAATTCAAATTCAATCTTCAAATCTCTGATTGGATCACAGAGGATTATAAGTCGAAATGGACAGTATAAAAAGAGTATCGTATAAAGCGTTTTAGCAATTATACTTTTCAATAAATGCGAAGTCAGTCACATCACGGCGATCGATTGTGCATTTGCTCGTCTCGTATGTACAATCGCGTGAGCACGCATAGATTGCACACGTATATGGAAACCGCATGTTTGGATGTCCTTGTCTTCAGTATACGATAATATTGACTCGCATAGAGAGCTTGATACGGTTTCGGGAGTAACCCCAGGGACACGCCATTACCGGTCTGGCACACCGTAATAATTTAATGGCGCGAATTAGGTCAATGCCGGCGAGGCGGCGATATTGCTTTTATATAGCCGTGCTTTCGTGCGGGTTTCACGAGCAATGCTCGCCATCTTAGCCAGAGAGATTTGCATTACAAAAGAGAAATCTGTTTTGAGCTTATCGCAAGCTGGTAGAAATCGGAACACCGCATGTTAAGCTGTTTTACGGAAAGAGAAGGGGgAGGGGGgAGGGACCACTTTTGTACGGCTCCATATTCGGATTGAAATTAACTTGTGTTTTTTTTtCCTTTACTTTTTTTtATCGGAATCGACTTGAGTTTATGAGCAATAATCTCGAGAAAAGGTGCATTGCAAATGGAATTCGCAAAGTGAAACTTGGCAATCTCTCGAAGTCGCTCGATAAGCCGAGCAAATTGCATTCATGCATTTGCGTGCCATGGCTTAGGACGATAATGTGATAAGACACATGATAAAAAGCTTAGTGCGACTTTAGTCTATATTTATTTACAACTTTGACTTTCATAGCTTCTATCTGAAAAAGAAATCTTGCGTTCTCTTTTTTTTTttATTTAAAAGAATAAAGAGTGAAAAATATTAAATCTCAATAATGATGGATTCGTGTTCTATCGGTTTTTAAATCAGGTAACAAATTACGTAAGTCGCATGCTTTTCTTCTTGCGACTCTTCTTGTACGTCGTACTTTTGAGGAGCGCAAAAATGTCTCCATCGGACGCTTTCAGAAATAACGAGCTGCGCGCTCTATCGACTCTGCTTTTTCCCGCTTAAACGGCTGAAGGAAGCTCCGTGATCTCGTTAAGTGCCGATTTTATGGTTTCTACGAATCGCACGCACGTGCAAAAGACACGCGGCTCTTCAGTCCAGGCCGAGCCGAGTCGAGCCGAAAGCGAGGGCGTCGCTTTAAATATAGCGTCCCCACGTCCCGTTGCATCTCCTTTTCTATTCCGCGGTATCCTCGAGGTGACATCCGCGCGCCCGGGTGGTGGGACGAACACGACCGAGCCGCGGCACGGTTATGGCGTTATGTCACGTTAATAACGTCCCGCGGTGTAAGCCGCTCCGATCTCTCCGCTATCCACGGCATTCGCGACCGCGACGTGGACGACTTTGAAGCTTTAATTAATGACGCACGGCGGAACGAGCTCGACGCGGACAGGCATGCCGAAATTGCATCGGTCCTCCTCATTTGCACGACGGCGGCGGCACGTCAAAACGTACGACGATAAATAATCCTCGTGGTCGGCGTAATCGTTGTTACGCCGCCGCCGCGTCGCCGGTTCCGCTACCGATCGCTACTGTCCAATCCCGGGATAACGAATGGTCATTTTCACGATTTAGCGTGGCACACTGTTAACTCCGTCGGTAGCGCGCTTTGATTCACGATTATGTCTGTAGCTTATAAATTCTCTAGCGCAATTCGCGCTTTGATGGCTTTTTCAACGGTCCTGGTACATAATAGTTATTGAATTCCCTAGCCGTTATCTAATTTTAATAATAACTGAGACACTATTGCGCATTTATATAGGATGTTTCAAGATTTTCATAGTACTTCTCGATCAAGTAATTTTAAATGTTCGGGCTTTTTGTTTCTTCAACGGAAATTGAATGCCCTTTTCATAAGATTGTAGTCTTCAATTTGAAACATCTTCGGAGCGAAGCATCAATGGAGAATAAGATTCTGTACTTAGCTATTTCAATACTATCTAACAATCCAATACAAATCTCGATAGTCTGTTAAATTTAAACGTCGTGTTAAAACATAGACTATTTACGTTCGATTTTGCACGTAGGCGCGAGAGCATTGCCAGGATTCCCAGGACACCCGGTGAATCTCGCGTGTAGCGAGACTCTCTCATGGCACGATAATCGATGGTGATCGACCTCGCACAGCCTCGAGAGCCGCCCTCTCAAGAGTTTAACGAGCCGGTTGTTCGTGGATAGGGACGAGGAGGGGCCACGTGCAATTCGCGAAAGATGGTCGGTATTTATAAACAGCGTACTCGAGAACTTCCCGACCGACGTGAGTGGGTGAGAGGAGGGCGAGGCGGATCGGAGTCGGCGAAGAAAAATGAAGGAAAGAAACGGACAGACGGGGAATCATCGACGTGCTCGAAATCGCGGCCGGATGCGCATGCAAATCTTTACCCGGGAGTCGAGCCCCCGAGTGAAGGAACCCGCAATTTGCGCGGCGCGGCGCGGCGCGGCGGCGATGCGGCCGGAGAACGGTGGTCTCGAACGGAGTAATTTCGCCATGGGATCGGCATTGTGTTCGGGAGATTAAAACTTTCCAATTTTCAACGGGAGTTCAGCGGCTGCCGCCGATCCCGGAGACTTTACGAGGGTATATCTCGTTATTGAATGGCTAGCTCGCTCGGGTATATATCGCCGTGCTCGTTGAACCGCCAATTAAAAAGTATTCGCTCTCCGAAGGGTCCGTATGCGCGGCGCGCGCGTCTGCAATTAGAATAAATCTGTTCTCTTCATAAATCTCGTCATAGTGCCGCTTGATTTGTCCCCGCGGAATCGGGGATGATACGGCATGCCACTTTTTCATCCTAAAACGAATCTGGAAAATTCATGCGTCGATGCTATTCTTCTCTCCTGATAAACATTGATTTATTGCACAGATATGATGGGCATAAATTTAGCGGATCTAGTTTCTCTTAATTTTTTTTTtAATTCATTAGAACGTAACAGCGGTTCTTCCCCAAAAATAAATATTTATATTAATTAAACAATTGTACAAATATTTAATAAAATAATTATATCAATTGCCCATTTGTGTAATTATTATATTTATGTTAATTAAATAATTAAACTGCAGTTATTAAATAATAAATTTACAACCAATCGCGGTAAACAAGCTTGAATTAGATAACACGCTAAATTTAAAGTAGGCTTATATTTTACATGTTTAGCTCAATAAAAGTTGAAAGAAATCTGATGGAAAAAACATTTTTGCTAAAATATCTAAAAATTTAACTTTTTACAGATCTGAAAATAATTTTGTTAGGTCATCAAAATAATTATGCTGGAACTCTCAAACTGATTGCTAGACTGTCAAAATTTTTTGCTCATCGTGCTTGGACATCTCTCATAATTATTTCGATGTTCCAGTACAATTATTTTCAAATCATCAAATGTTTAAATACTTCAGCAAAACCGTTCTTTCCGTATGTGATATTATGCAATATTAGCATTTCGCTGTAATCGTCGCTTATCCATCCATACAGCTTCGCGTTTGTTCCTTTCCCTCATAACAAACCGAGTGTTTCGCACGTGATTCCATCTACTGCCTTGAGATCAGCCGAAAACCACGTTCCACCATATTGAGCACGCGATTACGAGTCGCTATAAGAATATGGCTTAACCGAGACGAAGGGATTCCATAATACCCCGCTGTATGCTATGTAAACACGAATTACTGTTCCCCATCGGCGAGCGCGCGCTATTTTCACGCTGCCGAATATGAAATATAAATTGGATGCGGATATGGGTATTAAGAGATTTGCAATGCTTAAAGGTACATTGAGAAGTTCGATTTACTTGCGGGAAGCCCAATACGCTCCAACAAAAGCGTCTGAAACAACTCGTTCGTAAAGACAGCAATCAAAATGTTCAGGATTTTAAGAACGTATACAACTTTTATCGGACGATAGTTCAAATATTTAACAGTTAAATTAATAACCAAACAACGTAGAGATTAATTCAAAATGAACATAAAATAAAAAAGTTTACGATGCAAATTGTAAGCTATAAGTTATAAAGAATTTTATAAAGAAAGCTTAAAAAAaTAATTAGATTATTTCTAATAATTAGCAAAATACATATTCATACATGTATATCATTCAATCTGCGCATCCATATGTATCAGGATTTAGCGTTTCAGTTTCAATCATTTGTCACAAGTAATACAAACATTTAAATACTTCAGTATATAAAGTACTCATCGCCTTTCCATGCATTCTATAGGATTTGCCATTCTCGGCGGATTTAAACGTTATCCGGCTGGAGTTTGGAAGTAAATGTGCACGACTTTAATCGAGCATAAAGTTTAAACGGGGCATAAACTCGGCCGCTGTCAGGTCGATATTATATTTAAGCCGACGAAGAGGTACAGTTTGCGTTTCTAAGTTATTTTCGGTCCCGACACACACACGCGCTGCGAGAGTCGGCAACCTTATGAATTATTATTATTTGCATGGCCTTGAAAAGAGAGCAAATTGAAACGCGATGGCCAGGTGGTTCGAATCTTCTTCCTCCAGCCGTTCGCTACTTATTTTCGAGCGGGAGATTTTTCTTTTCTCCGGGCATTACTTTTAAGCGTTAGCCTTCGCCTTCGCCTTCGCAAGAAGTAAAAGTTGACTTCAACACTTCAGGGTGGTAAAAAGTAAAAGGATGTGTCCAAATATTGATACTACGTCAGCTTTTAAAATCGCTTTAATACCTTCTCATTCGATTGTCAAAAGGTATTCGGCATAAAGCACGATAGCTGATGACATTGACATTTTTTAATGTCAAGAACCTAAAGTTACTAAGAACCTTTCATATCTTTATATTAACAAAGGAAGTTTTCGTATAAATTATTTTTAATAAAATAATCATAAAAGAAAATTATTGGGAGGATAAGGAAACATTTATATTACAAGATAATTAATTTTATTAATTTTGTAAGAAAATGAAAAAATAACATTAAGAACAATGACATGTGCATTTTTCTCTGGTACGTTAAAATTTGCTTTATTAATAAATATTTTTAATTAAAAATACATTATCGTGCGACACTTTGATCAATTTGTGAATTTTATCGAGTGATGACAAAGCGCGATGAAATTTATCAGGCACAGACGTTGAATTCCATTCGGTAGCCGCATTGTCAGCAAGGTAAAACGCGTCTGGCTGTCATGCGTGTATGGAATCGCGGCTTTAATGATTTTATCGGTTAATGCAAATCGTAAGGGACGATAATTTATTCGATGGAAGTCGGTCACGGTGGCGTGGAAAGGAACGTAGTAGCCCGCACGTAGACATGTATTTTTGTCCGCGCCTGTTAGTTGTTCAAGCCGTAACAAGTCATCCGGACGACAGCCCTGTCGGACGGGTGCAGCTTTTCAAAGTCAGCTGTCATACCACGAAACGACGAAGAATAGAAGGTCCGAGCTGCTGAGACCCATACATCGAGCGTGCGTGGTCGTTCCCGAGATCTTATCGTCTCTATTTTCCTCTGATCTACGTCGTGACGTAAGATTTAATTAGGATCCTGCAGTAGACGAATACTAATTACGCATTTGCCGCGTTTTCGTTTAACATATTAATCGATTGCATGGCTCATATTAGAACATCAGTAATTGAAATCATCTTCATATAAAGATAGAATTATTATAAGAAATAGTAATTTGGGATTTTAACAGTACATTAGAGAGCATCTAATCACATCTTTGCGAATTTAATTAAAATCAGTACAATTTTGGTATCAAGACTAGAAAATATCAAATTTTTCGACAGAAATACACATTCAGGAGATATTAATATAATAATAATATAATGTGAATAAATTATATATTGTATTGAATTATATATTTTTtGGTTAATACAAAATGTCTATATATAAATTTGTAATGATATTTTATTTGCGCCACATATCGTATTCTATATAATTCTCATAATTATATTTATAATTAAATTGACCACAATTGGTTTTTTATATAACTGAAATGTTTTGAAATATAATATTGCTATTTTTTTAAGCCTATGATAAAGAATGTTGGTTACTTTATTCAATCCTCTCTCTAGAGAGAGGATGCGAATCTAACTTTTCAGCGAACCGTACGAGAACGATCGTtCGAAATTGAATTTTTTTtCGTACGTTTATCTTGCACGAAGTGGCGATTGCGACTACGTAAATCAGTTTATAAAAGCACGACAGTTTCCGCAACAGTTAAAATAAATATTCTACCTCAAAAGTTGTGTGGGGCAAAACAAGCGTGTAAAAACGGTCTGGCGGATTTAGCGACGCCAAAACTTACTTTACGCTGGTTCTCTTTTTATCGACGTTCCCCGCCTCGAAGTCGTTCAGTTAAGCGGGGCTCATTTCATTCTGCCGGCTGATTAAAAATCACGATATTAATGACCCGCTCCGAGTTAATATACATACCGGAGAATTCCCGCTGACGGGATCGCCCTCCAGCGGGTTGTGGGCAGACGTCGCTTAATACAACATAGACGATACCAGTCGCGCACCACGTAAATCACTCCGATGATTGTTAATTACTCGATTAATCGGCTGTACTCGTTGAAACGTAATAATGCCCTTATTTAATTACGAGCGAAAATAGATCTTGTTTGCTTGTATATGCTCTGCATCCCCGCGCCATTGATAACTGCTAACATATTGTTGCTACTGTGTTTGTTAACTCGTGTATTCGATGCAGCTATAATTTAGATTTCGTGTTACCGCGTGCTTCTGTCGCTTTCGTTACAACTACTACTAAATTGAAAAGCAACTACCTCTTCAATTTTCTAAACCAAGATATTTATTTTACGAAACTGAATTAAAATTAATTATTAATTACAAAGAGATATTTTTTTCACGACGCGTTTTAAATGCCCTCTAAACTGTGATGCAACTATAGATGCAATGGATTTACGCAGTCTCGTTATATCGGGATTTTAGCCAACCATAAACCAATCCATTAAGTGGAGTATTCCCACGAGAATTAAATGTATCTCTTGATGAATGGCGTAATTTTTCCCTTTTCCCATGCGCACCGAAGTGTAATCGCTTCTTGCCTCCCTTATAGATTAAAAATCGAGATACTAATAACATCCGCGTTGGCTGACGTAGATCCTGCCGTATCCACTCCGACAGGATCGTCTTTCAGTGCGCGCGAGACGGAGTTTCTTAAATCTACATGCACGTAGCAGCGCATCCTGCAAACGAAGCAGTCTATAATGCCTCTAGGCAGCCACATTTTTTGCATACTCAAAAGCCAATCCTTTATCCTCAAAGGTTAGATTAAAGCAATGACTATCCTATGCAACGAAATTTAAATCGTGAATGTGTGTTATTTGCAAAACGGTGGCAGGTAAAAATTTATCGTTAGAGAAACAGATACTTTGAAGTTGATTTCTAGTGAAAAAATCCAACAAAACTTTTTTGGAAATTTTCAATATAACAAGAATAATAAGAAATGTATAATAAAAATGACAGATAAGAAAAAGTTTCAGTAAATTAATAGAAATATGTATTTTAATATTAAAATATTAAAATATTAAAATATTAAAATACTAATATATTTCTATACTGTTACTCCAATATTTTAATATTTTTCAATAAAATATATAATTCCGCGTATAAAAGACTATTCTAAAAACATTCTAATTGGCTGCAATCTCTAATAAATCTTTGTAGTATACATTGCAATCTCGAAGAATGTGCGATACTGGAACATTCTATTGAAAAACGATACTCTGTGTACAGTGATGCATAACGTGAAATCGGTATGAAATCACAATCTACCCGAATGCTACACGAATAAAAAAATATGAGAGCATAAAAAGAAAATTCATACGTTCTAAAGCTAGTGTGTGCTACTTATCTTATATGACAAAGAAAGATTGTCCTCTGTATTTTATTGTTTTTACATCACATCTAAACATATCTATAATGCTATAATTTTTATAAAaTAAAATATTATTTACTACACATATACAAATAAAAAAaGAATAATAAATATTAATTAATAACTTAATGACAGTATTAACACATTAATTGTAAAGATGATCTCAACTCAGATGATAATTGTGTAAATAATTATATTTTAAAAATTATTACTAATACGTTTCAAAACAATATCGCCGAGAATCGCCAGGTTAATTTCTAGACTTTTCGTAATCCAACTCGAGATCTTTCGTTGTAAAAATACTTGGGTCTTGTCTGTTCCGGTCAGAGGTAATCCGACCGTACCCGAGAGATACGGAAGTCGGTCGGAGGAAACCAGAAGTCGATAGTTTCCGCGAGTAACGTTTCCATGCACTCACCGCGTATTAACCGTTGGGTTATCGGGGCCGAATGAGAGCGTTCGCTGCAATCGTAACTTCGAAATACCAGGATAGCACGTCGGCAATAAATGCCGGCCGCAATTACGGTCCGATGGATCGTATTTTTATTGATCTTCGCGAGCGCGTTCGCTGCTGGCAATCGTTACGATCGCCGCGTAATTCGGTAATTATCATCGCGATGTAATATGTCATCCGCGATTGTAAAGCCAGCTGGATCCCCCGTTTAGTAAATTCATCTGGTAATGGACCGATTATCGCAGCTACTTTCGATGGGAGAGCTCGTTGGGATTGATCTGTCACAATGGAGTCGATCGACGGGCAAATTCACAGAGCGATTGATGCGCCCTTTGTTTCGTAATGCACGCGCCATAGTGGCTGCCAGATTGTTGTGAATCAATGATAAGGGACATTGCGAGGCTCGAGTAATTATCCATGGGGCGCGCGTCAATGAGAATTTTTTCAATGCACTCGGTATTATAATTGTGCGAGTCACGTACATCACAAAAATTTGAAATCGTATCGATTGCAAGCTATATAAAAAGAACAATATGAAAAATATAAAGCGTAAATAATGTTTTTAATTTTAATGGCATTAAATTAAATTAAGAACTTTGTTAAGATTGTAATTTATATATTAAACGAATTACAAAATATGACATATGAAGAAAAATTGACAAACAATTCATTAAAGAGGATTTAGAAAACTGAAGGAAAGCATGCCAAGAAAACTTAATAAAAATTATTTAAGATAGGTATTACAACATAAGAACGAATAAGTTAGCTAGGATAAGCTCCATCTTGTCTTTATAAAGATGAATGTGCGAACCGGGATTTGAATATACATGAAGCATAAAACGAGCCTGAAGAGTTCACGTCAAAGAGGCCTTCCGTTCACGGCCGGAATAAAATCGAGATTGCCGAAGGTGAACTCATTTGAACGATCTGGGTTGCATAAAGTACTGTAAATTTTATTAAAACCGTTTTATTCGTTTTAAGCAAGGTTGTCAACAGGAGGACAGTGACGATAACCTAATGTATTTTTTGTTTCCGTAAAATCAGATAAATACGTATAAGGTAGAGATGTCAGATAAACCGCGAATTTATCGCGGATTTATGTCGAGCAATGATTTATACGCTTTGCATAATAAACAGCTTGATTTGGTCATACAATGGAAGCGTGTGCTCGTGATGGATGCATTAAATTCCACGAATTGTCACGATAAAAATGATATATGATTGCAAAAAATTAAATCTACTTTATTGCAGCTTCGTTTTGTAAGGTAGCATTTCTCGCGCAAAATGAATATAAATTTCAAACGAGAAATTAATATTTTAATATTTAATATAAAAGTACGCTTATTATCAAGAATTACGAATACATATTTAAAGAAAAAAAATGTCTTTTCTCGAAGTCTACGGGGTTCTAAAAAATTTGACAATGTGAAAATTTTATTAAAAGCGAGAAAAGGAATAATCGATTCCAGCGAATCTATCTATCCTCGAATCGAGAGAACGCAAGAAAACGTTGGGATTATTTGCTCGAGAGGACTCGGGGGTTGGAATGACGAGGGTTCGCTCTCCGTGGGGTGCGAATCAATGCGAGAAAAGTGATAACAATATGTAGATCAGATCTGGGCTATCAGTTACCTTTTCCCAGATCTCCGATTATGCGCTATTTATCGAAGTGATGGCGCAATAAATCTTATTTTCTAGACAAATTGATTTGGCTGTCGCGTACTTGCAGGTAATCGAGCTTTGTTTTATGACGGTATAAACAAACCTAACTAATTTAAGTGTTTGACAAATTTCTTTTCGATAATGTGTGTGCGCAAGCTCCGATCAATATTGCAATAGAATTTAACGACTGTACGCGCGGTGCGCACAAATTTACTCTGTCAAACGATTTATTACCAGAAAGATAGTAAGTTTACTTTGAAATTACTTTTTGAAAGTAACCGCGCAATTAATTACGGGAAATCGATCGCGGCACTGTAGAAACCGCGGTAACTCAGGTAAATTAACGATAGCTTTTGCAACAACTCTCCTCCGCGGAACTTCATTCACGCCGGAACACAATCCTTGGCCAGCACGCAATGCGGAAATTAATTTAATTAAACATCGTGAAGAAAGCGTATTGTGATGGAATCGCGAATTATGATTGTGTGATCTCTGTCGTATCGTGTTATGAAATAACGAACTAGAAGAATTTGTGACACAGGTGTAGAAAAGGATGGCATGAGAACCGCTGCTTAAGTAATGAGTGTGGATAAAAGAGATTAGACGGCCGAGCAGTTCTGTGCTTCGAAGGCATAACTAAGGTTTATTAACGGCTCTCTCCCTCTTCCTACCGGACTCCTTTCCATCCAGTTCATCGTATGATATTCATCTGCCTGCCTCTGGCCGGAGAGCCGTTGCTCGTACGACTTTTCGTCGTTTCTCTCGTTTCCGCCCGGCCTTTCTTCTATTTCTTCCCTTTGGACACGGTGCCTCCGCTGCCAAAGGCCGGCCAACAAGATCGTTATATTACGATGGTGTCAACGGTTTCCGGGCGTACGTTAAAACCGGGCGTCGCTGGCAATTTCGATGCAGATTTTTCGACCTTCTTTTGACACGCGGCGAAAAAGAGCCCAAGATCGCACGATAGAGAATCCTAATTTACGAGGAAGCTAACAGTGGCTTAATGTAGTGCTGCCTGATTTTAGCTGTTTTGAATACTTTTCGCATAAATTATCTCAGTTATATAGATATAAGATAGATTCTTTAGACCTTAACAAGGAAGACGATAAATATTTAACAAAGGAAAATGTATATTTATAAGTTAACAGAAAATGTACGTGTGTGGCAATAAAACTGAAAAGTTAGAAGATATTAATCTTTCAGTATGCTAAATATCATCTAAATGATATCGTGCAATGATAATATTCAAAATGCATTTCAGCTTTTATGAGACTGATAGATTTAATTAAGCGTACGTAAAGTTTATGTATCACGAGATAAAGCGAATTAATGCATCTCTAATGATCTGTGATAGATATCAAGTGACGGTATGTGTAAAGTACGAGCCAGGGAAGCACGATAATCGGATTCTGCATGTCTTAAGCTGATATCTTGGCGGACCGGAATATTACGTCGTTCTTGGCAAGGTCTATGCGCGTAACAAGTAGTCGGTGCACGACTACCATGCCGGCCGTGCCATTGTGATATGCGAATGGCTCCAAAAGATTCTGATATACGTAAGGACGTAGTGGTGAGATGCACCTGCCGGGTAAAGGGAATCGCTGCCGAGCGAGGCCGAGGGCTAGCCCGTCTAACCGGTACTGCCCTGTAAAATTCTCAACTATGCACTTAGTACGGTCGGCAGATACGCGATATATAGGGTGGTCTAAAATAAATTGTCGGCGCAAAGCAAATCCGCAATTATATCCTCGTAAGTCTTATCCGTTACGATAGTCTGATTAATTTTCCATTTAATTGCGTAATAAGATAAGGTGAAAGATCTGCATCGACAAGAGCCGACTCGCGGTGAGCTTGAAACTTCAGGTGCATTGTGAGTCAGTTTAGGTGTCTTGAAATGAACGGTAGCGACGAGCGACAGCAAACGAAGACTTCTCAAGATCGTTTTAATCACTCTCTAGATTACTTTGTCGAAGGAAGAAACTTGTTAGCAATTGAAGTATGGGATTCAATTTGATACCCATTCAGTAACAGCCCTCACGTTTTCAATATACATATATGTATAAGATCGAGATGCTTATTTCTAGAAAATTATTCTAGAGAGCTAAAGTAATCAATAATTTAAATAAGAAATAAAAAAaGTAGCAAATCTCTCTCTCTTTTCCTCTTTAAAAAAGTCGGGCAAGTTTGCTTAATTAACGTCTTCGCCAAGGTTCGTTGCAATGCCGTCTCGTTTGTCCAATTCATTAAGTTCAAAAATATTTGAGGCGAAGCTTCGCGCTTTGATCGATCGTCTTCGGTTATAAACATTTACTGGAAATTTGCAAACGTAGACGTCGCAACGTTTGGTCGAAAGTACACATCTGCAAATTTTAACAAAATCCATGGTAATAAACGAAACTGGAGCAAAGAGTCAGCCGAAACTTCGGACATAGCGTTACTCTCTAAGTCATCGTTTACACTTAGTCGTCTGCGAATTAGATGAATTCACGTATCGACGAATAACGAAAAGAGAAATAATGGCTGATAGCGCGGGGACGGACGGTCGTCTTACTTTCTTGTCTCGGTGTCCCGCAGTCGTGCATTCAAAGGAGTTAACGGAAACCGCATGCAGGCAGACGGAGTTCGCCTTGAATGGATGCTATCCTCCCCGTTGCCCTTCAACCGATGGAGCGCCAACGCGCTAGGTTTGCGTTTGTAATTAAATATTTGCCGGCGGTTAATTGAGTCGCGCTGTGCTTTTATTCCAATTTCTGGTTTAAATGAAACGGCACGGTCGTCCGCGGCGCAGACTTCTACCGGGTGTTCCCCGTCCACCCGTGTCGTACTTCTTTCACGTGGTTGCATAATTAAGCTCAGAAATTCGCGAAGCAAAGCAGACAAAGCGGCTTAAATGGCGGCAGCTGTACTCTGACTTTCCTCCGCAAATTTTGCATTTGTTAATAATGTTTACTAAAAATATATTGCATAATTAAAAAGTCTATTGTAATTATGTCCGTGGCATTACATACCCAAGCGGCACAAAATAGCATCAAAAATAAAATAGTATTTCACGTATGTTAGTATGCAGTCAATAGTCAGGAATTTACATTAGCCCAATTTAAAAGTGACGTATTTTGTAAATGTCCAGAAAGATAAATTTACCCTTTTAGTGTCTTGCTTTAATTGACATAAAAGAATTGAGTTAATCAAGATTCATCAAATATATTGAAACTGAATTGCACAATGAATCAATTTACTTTGAAAAATCAAATTACCTTCTAGATTTGTATATCCAGCTATTTTCGATCAAACCATTTCGTTTTTGTAGAATCGTATAATAATGTGAAATCAATGATGGCAACGAGTCTTGTATCACAGTCTCGAGATGAATTCCATAGTTAATTCTATTCGTTAATGCTGTGAGACAGCTATTTGTTTCGAAGAATTAAACGCGCTACACGCATACTTTAGTTCACAGTCAAACAAGCTATAATTCGCTTGGAACTTAATTGATGTGAAATAATTTAAACGTGAAGCATTGTATATTTATGTACAGCTACACCAAAAGTCGAAGTTATATCAGTTTTAAAGTAACAAAGTTTACGTAACAAAGTTATATCAGTTTTAAAGTAAGCTTTCTCAAGCGTATCCAATTACCTTTTAAGCATGCGATCAAATGATTATCATTAATTGTTACGAAAGAGAGAAACATACATATACATATATAATATATCACGTATAGTCATATGATGAAAGACACGTTTCATTTATAACTCCTAATCTTAAATTAACGTTTCCATAAGATAGGATATCTTACAAGGCATGCTGTTCTAATAAAAGCAAAAGACTCGCGCTAGAAAGCGCTAGAATATTTAAAGATTGGCGATAACTATCGCTCATGCAGACGATTGCAATAAATGCGCGAACAGTCTGACTTCCCATAAATCGTTTGCGACGTCTCAGTCGAGAGATCGCAGAATCGCGATCTCATCGCGTCGCGACGTATCTTCGCGACGATCTATCGCGGGACAACGTAGCTCTCATCGATATGTATGATCAAATCGTAGAACGGTCGGATGCAATCTCGTATAATTTGCAAAACGTGATGCGTGCCTTATTGTGATGTCTCAATAAGGCGGCCCCCGTCATTATCTCGCTGCACCATTCTCCCGGTGATGTGCATGTGCAACGCGACCGGATCTCCGCGCTGCGAGATAGATGCGGTCGTTGAATCAAATGCTTCTTGTGGAGGGCACACACCTCTCTCTTTCTCTCTCTTTCTCTCCTCCACTGCATCGTGCGCGCGACGTAAAAACATGAACGTTCACTACCATGTGTAATGCATTGCAGCTTACGCGCGAGGAGAGACGCGTGGCTTGCAGGTCTACCGTTAAAACGTGTTTGCTATTAGACACGCCGGCGAGCTCCGTCGCCGACTTCCGCGAATAATGCAAAGGGAGTGCTTTTACTTAGGTTAATCGAGATAAATGCCTGATGCCGCACGTGTGAATACATTTAATTAAGGAGGTTGGTCACGGTCGAGCGCGAGCGACACGCGGATTATCTTTTATACTTGTACGATAGCGTGGCGTATGTACGGATACTGCAGCTTATGAAGACGTACTGCACGGCGTGGCAATAAGCTTCTGCAAAGTAACTTGATTGATGCGTGCTACGACTAGCGTATAAAGTTTTACGTTTAACGATGAAATGGCGCGCAGCGAAGCCGATAATTTAGTTCCTATATTAGAGCATCTAATGCGTCATATGCATTACTACTACGTATGCTACATACAATTATGCATTGCATATAAATTATCGGATAACATTTACGGTAGGGGAGACGCGTAATAAAAGAGGTGCATTTAATTTTTTTTCTTTTTTTCAGACAAATAATGTAGATTCCCATTACCTTTGCATTCACTCTAAACGACCCATTAGCGGAAAAACGATACATTTACCGGTATTAATAACGAAAGCGGCATACCGCAGCATGGGTCTTATACCATTATCGGAACAACTCGATGTCTCCGAATAAAACAATTCGCCGTGCGTGCGTGTGCGTGAATGCGCACTCTGTAACCCCGACAAAAAAAGAGAAAATATCCGCGCGCTTTTGCGGCTATCCGCGAATTAAAGTATTATGAGCCGCGACATCAAAGCGAAAACTGTAATTTCATAAAACCCCCCTTCAGACTCTGTGCTACATCGTCGTAACGGTAAATCGTGCCGAAGTAATTGCGTGGAAAAGTGAAAAAAAGAAAGGGAGAAGGTGGATGGGGTGGAGGAGGGGGAGGAAGAGGTAGACGAGAAGAAGAAGGACGCGCACTCGCGACGATAATTAACGGCTGTTGCGGCGCGAGGCCATTTTAACAAATCTCTGCGACCGTAACGACCTCATCAACTCCGTTGACGCGCTAACTCGGTGTTATCGCGAAAACTCGACTGCGCCGGCAATTGCTGTTTCATGCATAGCGAAGTGCACCCATGGACCGCAACGGCAAACATTCTCATCGTTCTAACGTCGTATAATTCGCAATTTGATATCGCGTCATGTGTACCATGGCGCTGCTGCTTTCAATTCTCTCCGACGATTCTCCTCCCGTCGCGATAATATCGCGGGCGACCAGCGTGCCACTACGGCGAAGAGAAACGTAATTAATGATTAGTTAATAGCTTGGTGTCGAGATTTGCCACAGTGATCGATACAGGTAAAAGCGAGACAAACTTATAAAAGTTCCAGCTCAAAGATACAATTTTACATTCGACTTTTTCTTAATAAAGAATGACGTAGAACACTATAATATTTAGAATGTTTTGAACACTATTATAAGATAACAAATTTATTTTGTGTCGACATCTCTGATAATTAAACATTGCATTGAGAGAAAAAAACATCTTAAAACAAAAAATTTTATTTAACATAAAAATTACTTACTTGGTGAGTCCTAATAATTTATTTACCTGTAGTCAAGGTAAAATTTTTTTtAATTGAAATTTTTATATGAATAAAGTGAAAAAATAATTTTTAATCAAGTAATTTTTTTTGCAGTTCTAGAAAATATTTACTGTTAAAGTATTAATCAAGATAATCAAATTTGTTAACCTAAGAAAACAATTTAATTAAGTTTAATAATATTATTAACTTCTGCAAATTATTAAATGTAAAAAAATATAAGAATACAAAGTTATATATTTAAGGTAATATGTTTCCTTACTTAAACGTAAATATTTTTATTTAAACAGAAAAAAACAGATGCTTGCATCAAAATATATGATGTTAAGAAAATGTATATCTTTTCATTAAAAACATTTTTTCTCTCAGAGTATTATTTTCTCTTAGTAGTGCATTTTTCAGTTAAACGTAGAGCTAATATTTTTTGCTATTTATTTTtAATTTGGTAAACATTATCGCTTGCAATTCCGCGAAATCTCAAGTCCCATCTAGGTCCACCGTCGCAACGGAGATATTTCCATCAGCGAGGGTAATTTCCCCTGCTCTCGTGGTGCACGTCGAGGGGCACGTGCAGGCATCACGCCGCTGGCGCCGAAGATCGCGCACACGCCGCTCGTTCGTACTTACGTCGACTTATGTAAGGGTGCACGTAAGTGCGGCAAATTGCTCGTAAAACGTGCTGGGTGTGTTAATTCGTCTGGTAACGTTGAAGAAAATACAGAATTAGTTTCCGGACGTAAGTAATACAGACGTGGCCGTGCATGTCCCGCTAAGAAGGCATCGCCTTGCCGTCCGGAATACGGTTGACCAATTGTAACCGAATAGCGTCACGGGATTGTTAGGAACGCTATTAACTACCAAAGTCCATTTCAGGCGCAGCGTGAAATATTGATGAGGCTGGTGGAAATAGTTGAACGTTGTTACGCATTCGTTGAAATCTCCGCGCAACTTGACCATGTGAAAACCGGACGCAAGAAACGAATAATGAGTTAGTGTGTTGAATACAGAAGTTATCCTTTTGCTGGAAACTTATAATGAATAGGGATATGCGCGGGTATTCATGTAATTTAAGTCGAGTTTCTTATCTAATTTTGAATAGCCGAGTTATCAAATAGTCGGAAACTATATATATATATATATATTTTAAGCACTTTAATTATCGGTTAACTTTTTAACTATTAATATCTTACTGATTATTAAATTACAGATATTCAAAACGTTTTAATATATTGATTAAATCTTCTCTTTTCCCTACTGGAATCGATCATGTATTTTCACGATTATTAAAAATTATACAGAACCTATAAATCTTTTTACGTTTCATATCTGTATAATTTTTCTTCTGTCAATGCAACGCTAACAAAAATTAATACTAACAACAACTCTTGCATTGACAGAAAAAAAATTTATACGGATATATAAAATGTGAAAAGTTTTATATGAAATATAATTAAACAATAGACAATGTGATTTTGCATATTTTTTCTAATATGACACGTACTTGTAAGCAAAGTATTTGACAACTAAAATAATTCTCGGGACACATATCACATAAATTATATTACATATTCCGATAGAGACAAGGATGTTGAATGGCGAGAGAAAGAATTACTAAAAAAGCCGTATACTGAGACTGACATTTATGACGTGTATTCAACTCTTGATATATAATGTTGCTGAAAAAAAAACTTGCAAAGCCGCGTAAAATCCACGCGTCAGTTTTCGAAACGAAAAAGTTTTAATCCCTGCCATGGTTAAAGCCCGATCGATGCATTGATCCTTCGGTGATCAAATTGCACATCGCAGAAAGCATTTCTGCAATCGACGTTTGATGTTCACCGTTGTGAAAGTTCAATGTTAAAAAATTATTGCGATCTATATAATGCAATCGTTTGCGGTTTAAACACAATGCGTTCCGTGTTATTTTACCGAATCCGCCGTTGTAACATAATCCATTTTCGATGCATTTTATTAATCCTTAAAATAATTGATTAGTAAACTCAAATATTTTTGTTTTTATTTCATGCGATATAAAATGTATGCAGGATTTACATATTGCCAAAAAGCATATTTTACATGTTCTCTTTCCCATTTCACGTCCTTACGCTTAAACCAGAACTTTAAATATACTCGAACGCAATTTAAAAAAGTCTAGCGTGGCCAAAGAGTTAATTGCCGTATTGGCCATGTATAACAGAATTTCAGAGACACGCGGGCGTGAAAATATCAGCTGCCGCGTAGAAATAAATTACCTGGCAGCGCAGTTTTTCGTTTTTATCTCCGCACTTGACACCGTACGTGACTCGCCAAGTTTGTCGACCTTTATCTCGTTTTATTTCACGTGTCGTTGTACGCGTTAAAATCGCGGTCCGGCCGGACGGGGAAGTCAGGTGGTCGCGGCGAAATAAAAAGTACGATAGGAAAAAAaTAACCCCGGAAAGGTGGATGCAAACCGCACAGAATTCTCGATGAACATAGCGAAATGTAGGTATCGGAGCGAAATCGTACATACGCGTACGAGAATTGTACGAGTCATTGTCGAAACGGGCGAGCCTGTAGGAACAGCTTCATAAAGCATTACAGTCGTTCGATAGTGCCATGCTCGCTAATTGCCGTATCCTAGCAGCGATGGTGCGAGGCGAAACGATCTCGTGAATCTCCCGAGCGACCGTTTGCATCTTCTCTCTGTAGCTACATTTAAACGTAGCGATATTTCACCGATATCGTACCAACGCCGAGCTATATGCAGCTCATAACTCTCGTAGTTTTTAATTTTACATCGTGTCTCACCGTGTCGTATACGAATACTTAGGACCTGTGGCATTAACATAAATTTCATCTCTCGCAACAACGGGCGTAGGGTGAAGCCTCTCACGGATACAAGTTTTAATCAATCGATGGGACCGCCTCTCTGTCATCGGAATTGATCAAAGAGCCATTTTCGACGGCGATTATGACAACCTATCCTTTAATTATCCTCAAGCGACGGACTTGCGCTGCCGAAAAGAGGCCAAACTTTTTTGCGAAGCGTATTATCCGCTCGGCTCGAGCATGAGCTTGTTTTCACTTCAAATCACTATCTATCATCGAATCAATTAGCGACTTCTCGATTACCGACTCGTCGTGCAACGGCCGTGCAAAATTATGCGACGGATCGATGATCGAACGATCGACTCGTCGCGAACACGAGGCCGAATTTACGAGCGAGACACGTTTGATTTATGAGACGGCATCCTTCGTTGATCTACGCTCGATCTACGAGAGAATCAGAGAGGGAAGGGGGGgAAGCGGCCGCAAACGCACAGTACACGAAGTTAATCGTTATTCTTGTCCGGGAAGCAAGGACGATAATTAATAGCCAATCAACGGGTGTGTTGGGTTGAATGTTAAGTAGAGACGCGTAGCGGCGCGCCGCTGCGCTTCCCGTTGGATTCGCTCGTGGTCAGCACAAACGATGTCAATATCGATAACGATATCCGTGTCCGGGGAAAATCGCCGATCGCGCAATACCGCGCGATTCGGCGTTTCGCGCGGCCGTGCAAAAATCGAATAAAAATAATCGCGCGTGATACCGTCGCGCTAACGCGAAATAATATTTTTGCTCTCGCACGCGGGGGGACGCGGCGGCGTAACAACTTGTACTCGCGAGTTTATTTGCAAAAACGCGCTGGAGATAAAATGCATATATGCCCGATACGTACCGGCCTTCGCACTCTGCCTGCATTATAACTGAATTCCGTGAAATAATTAAATTTATACAAGTTTGTTAATTGATGTGTTACGTGCGTTCGCGCTCAAAGTTAAAAGTTCAAAAGGCTGCCAAGTAATCATTCTCTAAAAATTTGATTTACATTTTTAAATGCCCCAAACGTTTGTTCCACTTTCGAAACTAAATTGAAGATTAAATATATTCGATGGGAGGAAAAAGAGCGAAGGAGAGAGCAAAGAATCTTCAAAATAATCTCGCATTAAAAAGTCTAATAACGTTTTATCTTTTAAAATTCAATATGCGCGAAATCAAAATTTCAAAATAAGACACCAATTTAAATTGAAATTAAAGTGGGATTTTCACAATCTCTTACTGATTACATATTCCGCGATATCGCGCCATAAGTCAAAGTAGGCACCCTCGTGAATATAATCATCGATTCTGATTTCGTGTCACGTCATATGACTCCGTCTTGACTAGATATAATCTTCTACGTCAGGCTATCTGGGCCACATCGGTATCTGAGAGAATATCTGAAGGGCTTGCGCGTCATCAAGGTTCCGAGAGTTTCCAGCGGAAACGTGTCGTTATCGCGACAATCCCTTGGGGATTTCAGCATTTTGTCACGAATAACAGGGCTTTCGCCATTCTTTTACTCTTGCACGGTTCCCTACTTATGTCGTGGCAATAGTGCAGTAACAACAAGATGCACTACGGTCGCGTATAGCGGAGCGGATAGAAGCGCGCACAGGGAGCGGAAAATTCTACGGGGCTAACGTAATGTACGCTGCAAATAATTTCGGCGTGAGCACGAAGCTGTCTCTTTGTAGTGCGGCTCTTTGCCGCCTCCGTCTTATTTCCTCGCTTATTTTTCGCGCGGTGACCCCATTACGTATGTATACTTGAATAACGATACGACGCCGACGCAAATGCTGTATCGCTCGGGACTCGTCCGGCCAAGATGCGCCGAGGAGATACTGCGATATTATTCAGCGATACGATGGTGCATCCGCGAGACGGTCTGTCGGGAATCATGACGCGCCAGCTTATGAAATTATGGATTACAGACTGTCTCGACCGTTTTGGAAATCTGATTTCGTGTTTCCTCGAATGCTAATTAATTTCTTAATTATCATGCACGCTGAAAATGACGATCAAAGTTTAGATAACTTATTAATATTGAATATTAAAGTATTTTGTTCTCTTTCTCCTAAATATTATTTTTTtACGAATATGATCGTATTACTTTTTTATTTAAATTTTTCAATAAATTATTTTTTTATAAAAAATTCTTTGCGCACTGAGAGAAAAAATATTTTGACACAAAAAAATTATTTATTCAGAGAATCCTAATAGCATATTTACTTGCAGTCAAGTTAAAAATTTCTTAATTTAAATATTTATATAAACAAAATAAAGAAACAATTTTTGTAATAATAATCAAAAGTAATTTTTTTTGCGGTTCTAGAAAATATTTACTGTTAGACTATTTTTAAATTTAAGACAATAAAATTTTTTAATTGAAAAAAAaTTTAATTAAATTTAACGATATTGCTAGCTATAAAAAaTCATTTAAATGTAAAAAaTACAAAATTACATATTTAAGGTAATATATCTATTTAATTAAAATAAATATTTTTACTAAACTAGAACAAACAAATACTTGCATCAAAATGTATAGTTAAAAAAAAAaTGTATTTTTTTTtATTTTtCATTAAAAAAaTTTTTTTCTCAGTGTAACAGTTAAGCGAATCTCTCGCTGTAAATACCATTGATTTTCTTTTTCCCTGTCGTTTTAAAGTTATTTAACTAAAAAATTTACAAATATATACGTAACGTAAGTAAAATAAATCACGCATGCTACAGAACATGTTTGTAAACTATTATAACAGTATCGAGTAATTTTAACGTATATTCGAAAATTCCGAATCCAGAAATGGCACGTCCACAATAAGGAACTGTGTTAGTGACAGTTGCGATATTTTTCCAATCTAAATCCAAAACTGTTTCTTTAACTTTTGCATTGACAAAGAGTGAGATTTTTCTTCTGTATAGCAGAGAGAGAACTCGATCTGTATGCACGCAATTCGTATACTATCAAAGTATGACCATATGTGAAAATAAAGTCGAGGACTGCGTAAATGCAAAATCCCCGAGCGTGTTTCATACAAGCTCGTGTGAAACGCAAAATGCATCCACGGAAGGTATCACAGTTTGTTACTTTGAAATATTGCCTCTCATAAGAGGCATCTACAGTCACAGCGACTTTTATGTGGTGTAATAAATCTGGCGCTAGTGCATTTTATTCAAATTTACTTCAAAATGACCTCGCCTACCACATAATTTGGTTCCGCATCGGTTGATCTTACGGCAAGAAGTATCTCTATCTCTCGATTCCGCAAAAATTGCAAAAATACTCACGGCAACAGCTTATTAGCTAACAATATAGCCGATATATGTGACGTTAAAAAAAGTGGCTGATTATTATCACTGATATAGTAATTTTGTGTAATTGTATACTCTCTGCGTTACGTACAATTGTAGGGTACTGTGTTATCTGTACTATCTCTTAACGCCATTAATGCGAATTGTAAGTAAAGTTCTTCCCGCGCGACTATCAGCGGAAATGGATCCCCTGAGGAGGTACGCGTTTAATGATAACGCATTTAGCTAGCGAGGACTGGCGTTTCTCTCGTCGGCATGGATAATGATCCCTCGAGCGGTACTCGGCACTCATTTAATTCCCAACTTTTCCTTTCACGGTCGGGCGAGTAGCGCGCGTAAGGAGAAACATCCGGGGGAGAAAACGAGAGGGAGAAAGCAGACGAGTAGCGAAAGCGAAGAAGAATCCAGCGGCAAGGACAACGACGGGTGCGCTCTCCAGGGTCGAGACCTTAGGTAGGATAAGACAGAGAGGCGGTGCCATAGGGGTCAGGGCAAAAAATAAGAAAGGAATCGCGAGGGAGAGTACCGAGGACACGGAAGACGAGCAGCTCGCAGGCGAGACGAGTCTGCCAGGAATAAAGTTTCCTGTCGAGGTGGTCGCACGGGCTCTCGAGAGACTCCAAACACGAGGTGAGTTTCGACCCACCCTCTCTCCTCGTTGATCGCACGGCGCCGCCGAACTACCAACTCGCCCTTTCTAGACGTCCCTACCCAACATCCAGCGTCAAGTTGCCTTACATGGTAGTTGTTGATTGTTTCCGGTGTAATTATAACTTCGACTTAGGCGGACCCTCCTCAGATATAATTATTAATTACCGTGTCGGTGCCGCGTGTTGAAGGTATTCGCGCACGCGCCGCGGAAGACAAAGGTGAGCGCCTCTTGAACAAACTAATGCAAAGTATCGCTCGTTGTGTGTCTTGAAGTCGACGCCGAACGAAGCTCGAGAGAATTCTAAATTGCGACAAGTGGATCTTAAATGGATATTACGCTCACGAATGGTTAAGCGACTCTTAGAAAGATAACATTTTTTGCTAAATAACATTTTAGAACTTTATTTGTAATAATTTGTAAACTCTCTATAAAAAAAACAAATTTTAATACGTTTTTAACATATTTAACAGGTAGATCTTAGGATAATAAACATGTTATCAAACATCACATGTAAAAGTTTTTCACTCGCGTAACAGAGTTTTTAAAAGATTCTATTGTTCCGCACTATTAGTTGCATTTTTAAGCTCTCGGGATGGAATTGAATAATAGAGTTGGGTCGATTTCTTATCCCCATTTTGTCAGTAAGAAAAAGGAGTTCTTTGGTGTGAAAGAACTACTTTAAAATTCATAGAACGGTCGTGAGTGAAGTGGAGAAACTTATTCCTCTCTCACAGCCGTTGATCTGAAATTGAAAGGTATGATTTCAAAACTTCGCCCGCTTGTAAAAGCTTTTAGACTCCATTGCTTTTGTTTTAATAAATATCTGCACATCCGTTTAAATATATACGTATGTAACATTAATAAAATTGTTTTATACATTATACGTGTAAAACGATTTTATTAATATGCATTTATAATGTTCCATGAACTAAACGTAAAAATTTTCACATATATTTAATTAATCCGACAGATCAAATTATACAATAAATTATTTCGTGCAAAAGAATCAATAAATTTTACTGAAATTATGGTAAAGAGATAAAATATTTAATTATCGAATAGCTTTCAATGTTCCAAGCGCAATTACGTTTATCGATACAAATTGTATAGGTACTATCTTTTTATGTGATCTACAGACTACAGAAATTCTCTCGGCAGCTTGATATATTACAAACGTTACAACAATGATTTATATATATATAAAAAAAaCGTGTAAAGACGCACGATTTCCGTGGAAATGTCGCTCGTTATAGTACACGTGCGATGGCACATGCATACCTAACGCGCCATTATGTTCGTTGCCGCGCTAGCATTCCGGGAAACGCTAATGAACGTGCTGTGTCGCGAAAACACCCACGGACATTCGCAATCGCAATCAAACGGCGATCAACGGCGCGTTGATGCACTCTGCCGCGCCTGATTAAACAACGAGTCGTCATCGCCCCCGTCCGCAAAATGCAAATGCAGTCCGAATCACTCGAAGACGCCCACCGTGCGCGCTGCGTGTACCGTGCCATATGTTACGATATTCTGCGGTTGAATTTGCACACACAGCAACCGGGCGCGGTGTGGTTACTGCATACCCACACGCATACGGAGACACACGCGTATGGACAACTCAGACCCAACACGCATACAGAGATACGCGTGCGAGGCGCGCGCGGCTGGCGACGCGTCGTCGGCGTCTCCGAGGGTTCGCCGTATCTGCATGAGCAGTAAGAGCATCGATCACACACCGGGGACAATATTGGCATGATAATCGGAAGGGATTCGGCACGGTTACGTAGTAACATGGGCCAAGGGAGAACGGCCCTTGTCAATGCCGCGGTTACGATCGCGGAGGCTGTTTACTCCCCGGTAaTTATTGTGAAATATGTCGTAGCAGATCGAGTGCGCCGTGACGTGTAAATTATTGCCGCGGCAGACGCATACGTATGCACTTTTGTACGATCGTACGAGGATGACGAATTTCTCAATCTTCGTAATTCAGACGTTTGTCAAATAGATAATTTGATTGCTTGAAACTGGAACGATCGGGCTCGATCTGTCGTTCTATCAGCAAATAGAAAAAGAGAAATGTGCACCCTGCAGTCATCTCTGAAAGTTGTTTTTGTAATTGCAAAATGCAGAATTGTTGTCATTCTAGTTTTACTGCACCGAGATTAATCGTATACAAATAATAATATAAATTTTGCACATAGAATTTGTCATCGACCGGTTTGGTCATAAAGATTTAAGCACATCAGCAATTTTTAGTGCCTTAAAAGAAAACATATATCTATATCTTCTATTGTGATCTCGTAATCACTGCTTGAATTTTTTGAATGTCGCAAGAACGACACCTTCCCTTCTCCATTCTTAATCTCAATATTTAACTGAGATCCCTCGGTTATAGGGTGTATCGAGACACATTTCGTATACATCGACGCGCGGTTCAACAGTGTGTGCGATCCGTCGTTACATAAGCGCGCGCGGTGCAGTCAGAGTTGCGGCAATGGGGGTGTGCGATGTGTTGTGTGGTGAATCATGTACTACCCTCGAGGGATCCATCTACGATTAATTCCATCACTTGACACGCTTCTGAGCGCGTACTCGCGCGCACCCTACCAACCGCTCGACAAACATTTAAGCGGGGCATAAATGCCACGAGCGAAGTGGAAAATGAAGAAAGGCGATGCCAAATGCGCCGTGAAGCGCGAAAGAATTAGATGATGCCGCGAGAGCGCTCGATGAGACGTGAGCTGAATTCGCTTAATGCACGCATTTGATCCCCCGCCGTCCTCTCTTGCGACGTTTCCCATTTTCTCAAAGCCCCGTCTCTCGCCAAAGCGCCAAAAACGATCCCTCGGTACAGGGTATACGTTACGTCATCTGACAGAAAAAATTTTCACGATAAACGCTGTGGTTGATAAAATATAAAAAAAATATCATTTTTTCAGAATTTTATATTGTATCATTCCGTGGGAAACGCGCAGAAATATTCACGACTATATTTGTGTGTATGTCCAATAACTGTAAATGTAGAATATTCAACTAGCAAAACGTGCACTGGCAACGCCGGCGCCGGCATCCAGTGGATTATATAAAACATATTTTCTATGCGTGTAATTTATCAAATATGGTCATAAATGCGCATATATGCCACGTGTTAATATAGCTATGCACTTTTTCTAAATGTATTCCCTCAATGTCGGCAATTTGATATGTAATTAAGTTTTTTTtATCCCAATTTGTTTAATTGCTGGTTTTACTCGGAAAAATATTAAAAAACAGCGCGCGAGACCATTTTATTTCTTTATAACTTGTTTTACGCTTATTTTTCATTTAATCTCTTACAAAGCGAAATATGGTAGAAAGCTCTTCGCTAAAACGCAACGCTGTGAATAACGTTTTCTAAAGGTGCATATTATTTTTTTCTCGACGTCCAAACTAATTAACGCGCGGAGGTGCGAGGCACGAACTAGTTAACGCGGTGCAGGTGCGCTCGCGCTACTTACAATTTAAACTGATCTTAAACTAGGCTTTAGTCTTAACTTAAATTAAGCTCGTGCGGGGTAGAATAACAGAACTAATTGGATGGACGAGCGCGCCCGCTCTGCGATTAGCGAGGGCGAATCATAAAGCGTTATCGCGTAATTCATACAGTTTTATAAACCTGCAGTGAGCGTTGGCTATTAATCGGCTGTTCCAAAAACAACGGGGAATAAAAATTATGCAAATTGATCAGCAAAATTTAATGTCACTGTGATAACAATAGTAAGAGAAAATAGGAATTTTAATAGTATGTTTATTTATTCACACAAAACGTAAATTAAATTAATCCATTAAAATAAAATGCACGAAACCCTTGTCTTCAATTTAATAATTTATAACGAGCGATAACGGTGATAGAAGAATATCTCATGTCTACTTTACAGTGAATATCAGCTCCGTACAAAAAAATTAACAAATGTCTTTGCAAGTGAGCTGCACATTTACATTTATCTGTGAACAATTCTTTTAGAAAGCAGCCGCCTGTCACACACAATTTAATAACGAAAGAATATCGTAATGCTATAACCCGATAATTTAATAAGGCGTACATCAAATTAATCTCGCCTTTCAAAAAAAGAAATTAAATAAAGTCACTTAAGTGCACATATACTTATGTTGCATACGTTGTAAAGATATGAAGATAAAAGAAATATTATATTATTATGCAGCTTAATTTTTCCCTTCTCACTCATTTTTAACTCTGAAATCCTTGTCAAGATACTGCATTTTTGCATCAGAATTTTATATCGTATAAGTGGATTAAAGTTGCATGTAATATTGCGATCGCTATTGCATTATCTGGAACGAAACATCAAATGCTTGACAAAACGCTTCAAATAGACACGTCTGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGTACGTTATATCATATCCCATTTGCAAGTCCCACCGTGACGCGATCTTTTTTTCTTTCTGTTTTTGGTCGACCGCGCCGTTACGCATCGGGGCACGTGCTGTTTTACGACTGTGCGCGTAACGAGCGAGATGCGCGCGAGAAGATCGAGAACGAGTGGGTGGGTGGCTTGCGCTCGGATATCGAAAACGCGAAATTGGCCGTTGGCCATAAATCATTCGCCGGTCGGTCGGTCGGTCGGTCGGTCGGTCGGTCGGTCGGTCGGTCGGTCGGTCGTTCATTCGTTTGTTCGTTCGTTCGGACTCGTTCCGTTCCAGGGCCACCCTGAACGCGTTCGCTGCCTAATCAGTTTAAGTGATTCCGAAAGGCGCTGCCGCTGCACCATCTCGCTCCGCGTAACGACTGGCACCGCTTACACATACGCGCCCCGTGGTGGTCCACGTGCGTAGGCGGATGCTGCACCGTGTTACGCGTACACGCACGCATCCACACACACACAATGTTCGTTCCCCGTTCAGCTGACAACTCACGTTCGCCGTTTCTCTCGCGTGTTCATGCGCGGTGTCTGTTTTCCTTCTTTAGCATTACCATACTAATTACAGTTCAAGTACTAACTAGGATGTCTCTGGTCTATTGGCGATGAAACCTTTTTGCTTCAACGCATCACTGTGCACGCAAAAGGCGTGCACAGTCGTCACCTCAATGTTGTTTTGAGTTACAATATCCTGTGAAAGCATACGAGCATATGTGCAAAAGTATATTGGACGTTTTTGCAAATTAAAAATTTTTTAATCAACAATATGCATATTTATCTCGAGAACTAAAAATAAATAACTGATTCTATCTTTATTTAACGTAATCTGTTGCTTTTATAATTAAAAAGGTATACAAATGTATATTATTCGCTTTTTGTAATAATAAAAAACATTAATGCATGAGTCATTCTACGAAGTACTAAAATGAGCCAGATATTGACGAGAGAAAAAGAAAAACAGGAGGGTGCAGAATAGAACTTATCCATTTAAAGCGCGATAGAAAATCGAACGACGCGGAGCGCGTATAGAAGCGCATTAAGAAATGAAATTCGAAGGTAGCGTCGAAGGATCGATAGCGAGGAATCACCGGAGGCATTCTTCAAAAGGGACACTCCCGCGTCCCTATTGTCACATCGGATCTTGTCTATGCGCGATGCAAAATTCCCCAGCGAGGCGGATCGCGTCCCGGGAGAGGAGTTTCGTGCAAGCTTCGCACACACGCGCGGAATTAGATTAAAGACATTAAAGTCACCCTCTCGCGCACGACACGTAAGGCCGCCCCGCTAGTCATTCCGTGATTGCCTCCCGGACGGAATGAGTGCCCGCTGGACCGCGAAACGAAATTAGAATCCTAATAATACGCGGAATTTAAAGTCGCACGCCCGGGTATGAATAACGCATGCAGCGGGGTGCACGGCTGCTCACTTTGCTCCTTGCACAAAGTCAGCGACACTGGCGTGACGATTGTGTGCGAAGGGATCGCCGGCCTGTCACGACTGTTTATGCAATCTGCCCCGCGTCAACGGTAAAGCAATATGTTCCTATAGATTTACTTTCGGCTGTGGAAAGCCTAGATGTGATTACATATCTAGGACTTCGTCGATCAATTTATTTTCGATGCAAGAATTTTATCGTCATTTCTCAACTACGATAGCTCTATAAGATTTCAAGATAAAGAGAACAGTAAAATGTAATTATTATAATTCGTATTTTTAGTGGTTATATTTACAGATGCGCATACAAAATTATTAAATACAAAATTATTAGCATGTAGATTGTAATATATCTGGAAGTTATACGATGCAGTTCCTTTAGAAAACGTTCATATCGAATGTTACATAGCTGCTTATTATACTTAAACATGATGTATAAGTGTAATAAGCAACTATGTTACTGGATACTTACTACTCACACGTGCGCATATATATTAAATATCGACGCCGCAGTATGACGCATGAGAGCGAGCCACGTGCTATACGAGAAAGGGACACTTAATCTTTTCGTAGATTCCCCGTGGATTCCGCTGGGGGTTCCTGAATATTTTCACACTCCCGCCCCCGCGGTGTGGTCCCACTCTCCGAAGAATCGGACGGCGCCGCTTCTATCGCACTACCGACCCCCCCGATGACGTCTGTTTTGTAACTATTTTCCGCCACCTTCTTTACCCCTGAGTGCCCCTTCGTCTATGACTATGCGAGTATTCGCAACGAGGGAGTCCACTTGCCGCATCTCATATATGAGGGGGGGTACCCATACGAAATGTCGGAACATACGCGTCCACAGGATTAAGCCGGGGGgATCGTATGGTTAATGGACAAAGGGGGAATACGCGTCTGCGGATCCAATTTCGAATTCTACGCTTCGTGAAATTGACGGGTGCGTTTGTGCGAGTGAAGTGCTACTTTTCTTTTGTTGCAATGCGGTCGGCAGACAGACAATATGGGAAACATCTCGGTTGCCCGGATCTAATAACAAATTCAAAAACAaGATAGAGAGAGAGAGAGAGAGAGAGACGTTACATAAAAATTAATTTTTTATTCTTGCCAAAATCTGAGCGATACTTTTTTTACTTATGGATAATACTTATCATTCATAAAATTTTATTCATATAATCTGTTTACTTGGATAAATTTTtAAATTAAATTTTTTTTtAACTAGTCGCTATATCCTACGTAATAATGGGAAAAGAGCTTTCAACAGGTGTTTAAAATTAGTGAAACAAATGTATTTAAATTTATACTGGATTCTTAGTCTTAAGCCAACGACCGTTGAATCCTCTTTTAATTTGTATCAATGTAGTGTTTCGCTCAAGGTATCGAAAGAATATTAGAGCAAAGTTATTTTATTAGAAAAAAAGAGAATTCTCTCTAATTATTATTTTCTAAACTTTTTTTAACGCTTTTTATTATTTAATATATGTAATTTTGTGAAGATTATTTTTCTAATTCAAATATTTGTAAGTTATATATTTTTGTATACAGTATTGTTAAAATATTTCAAGAATAGCGTAGTTCTCATTTTCATGATTCTGCAATCACTAAAGTGCAGTTATAAGGAAGCATTGATTTGAGATTTAGAGTAATTTTTCCTTGCTTTCTTCGACAAGTACGCTTCACATAATCCAAGCGCTAGAGTATGAAGTACGAAATTCACGTTCCTCTGCCATTAAACACGATGAGCTATTGAATCATTGACGGTACTGCATAGTACGAAGATCGGCAGTAATCGGCGAGAGGAGATGGAATTTTCTAACAAATAGGGCATCCAGAATTTCACGATTCGTTGAGGCGAGAGCCGCCTCGGGGCGATAACATCGAACGGCGCTTAATATCGTTTCCAGGGCGAAAGACAAAAGCGGCACCTGCCCCTTCTCACGAGCGTACCGCGCATCTTCCCGATGTGAAGGACGATGGAAGGAGTGTAGGAGGAGTAAAGTGGTGCGATCGGTCCTCTCCTAATTCAATCCCGTGGGATATCGGCAACCCTAGGGCGCGATATCGTGCCGAGGCGTGAATCAGCACGCCCGTGAATTATCCACCTCGTTTATCGAGAAAATTGTAGCCCAGGAAAGATACCGGACGAGTCCCATTGTCCCGTATAACTGCCGCGTGCCTACGCTATTGCATAATACTCTCAATTCAACGGAGATGCGTGTTCCCGATGTCGATGCGCTGGCTCTCGGCCCTGCCAGGGCATCTATGGTGCCCCGGCTCTTAATGCCAGCCCGTAACTCTCGTCTGTCGATTCTCGGTTATGCGTGATTAATCATTCGCTTCGATTGCACTCTGACATTTGTGGTAGGCAATTGCGATCTTGGTGAAGTGTCTTGAAAGCAGGAGACGGTATCGCCAAATCGTATTGACATAAAAGATAAGAATAGTACTCAATTAACATTAACACTGTCCAGTCTCTATTATGTAATAAAATTAGATGAACCGTAATTTGAGGAAGCACGCAATTATATAACAGGTTTACGTTTAGTAAAATGTGAAAATTCAAGTATCGGGATTTACAATAGCATAACGCGAACCTATAAATTTATCTTTGTCTATCACTATCTTAATATTGTACTATATATTAGAGTTATGATGACTTCCTGCATTTATTACATGTAGAGTTGGACATATGTATCAACGAACTTTCGCGCCGTTACGGTAGCTCTTTGCTCGGAGCGTGGGCTTTCCGAAGTGTGTACATTATGTATGGTTGCTTGCTATAGTCAGTAGTTGGGCCCGATAGGCACCGGTATTCATATATTCATTGAATAATTGCGGGATACGCGTATCGTCTCGCCGAGGAAGAGGGTCCTGCATTCCCGCAGGAACAGGACACGCCCCGGCGATCAGACACGCGGCAATGAGGTAGGGTTACTTGGCGAGAAGAGCGACTTTCACGGGTCGACGGACACCTACCAAGGAGGAGCGTACTCTTCAGGGCGTGCAAATCAAACTAGCACCTGTTACCGGAAAAACACGCGTTTCACGACACGTTAAGGCGCGATTAATTTTTACAGACTCGATTCACGGCGTCGCGTTCCAAACTTGTTCACGAGACGAGAGCGTGCAAATGTTTAATTCATGAAACGTTTCCTTTTTGGTAAGAACGAGAGCAACGTAGTCGGGGACTGAATTATAAATTAAGCGAAGCAGATTGGTTGAACATTTAATCGTACAATATTCTGCGACGAATAAACCTACCTTGCACTGTGCAAATATATCTTTTGATCAATTTTCACATTTATCAGTAAACGGTATCCTCGGTGTAATTTACTATAACCTCCAGGCTGCAACCCGTTATTAAATATACATGCACGAATCATATCCATGCATGATAGCCTGATGTCTGATGCATGGATAGCTGACGTCGGGCTTCGGTCATGCGAACGATCAGCAAGATAATCGAAACACCCACGTGTCTGATTATGTGAATTCCTAATCTGACTTTTCATTTTGCAACGACGGCATTGCGGAAGTTGAATTGTATGCACGCGAAACGCCGCGCCGCGCGCCACGCCGCGTCGCCGGGTCGAATGTATCTCGATCGATTTGACGAGAGGTCTCGTAACGCATCGGCATTAATTTTGGCGGCGGCGCTTCATTATCATATAGACGAGTGTTTCGTCGAGCGTTATTGGATCTCTCGCGTCACGACGGAACGACACACGCACGTGCGTATACGTGCTTAGGGTAAACGCGCGTAAGGTTGCCTGTTCATGGCTTCCGGCCAAAGAATAACGATCGCTGCGAGTGTCGGCGTTACCCGGCGAACTATGACGGGCGACTTTGTCGGGTTAAGCTCTCGTAGCTTGGCATAGTAATCACGCTCTGATCCTTGCCAGAGATGCCTTTTATCGCGTGTTTTGCCGACGTTAAATAATTATGGCCCATACACGGGCGTACGTATCTCCGCTTTATTCGTTATAATAACGTTGCGTCGCATCGTACTTTCACGGTGCAGCATTATGCACTTTAAGTAAGTAATGACATATCGCCGCGACGAGGCGATCCCGACCAACTACATCGTTTGACATTCGCGTATCTCATTACGTCGTAAAGTACGCGATAACGGCCGCGTATTGTGACGAGCCCGTAATAATTCCTTACACATATTCCACGTTATTCTCTTCACACAACTTTTTAGATACTCGGCTATCTTTTCGAGGTATAAAGCACCTGTGCTTGTGTTCCATAAGTATGCGCATCCGTCGGATGAAAAAGAAAAAAAAaGTATGAACGTGCGCCTCTTAAAACTCGCCGTTGATGCATACGCCCTGCACCGATATCTGCCTTTATACCTTCCTCTTTTCCATATAACGTCAGCGATGCATCTTTCCGCTTGTTTGATACATTTTACGAGACGATCCATTCATCGTACACACAAGAACGATCTACATCTCCGCGCTGTCCGGGCCGAAGTTCACGATCAGAAAGGGCATAAATTATAAAGCAGCAGTTCGATCACCGTTAACGGCGTTGAAGCGCATCCGGCTGTCAGCGGATATCACGATCGAAAAGGGCATAGATTATCAACCGTTTCTATCGAATTTCCCTGCAACGGGGCTCGGGGGTGTCCGCTGGGACTCGGCCGCACGAAAGACTTCGTGCGTTACGACGATGTACGTATGTACAAGCACTCTCCGTAGGCCGTGCTCGGTAACCCAGTTTAGGGTTGGTTCTCTGCATGGGAAAGTGGAAAGGCACTTACGACTTCCTACAAGGGAACGATCGCGCGCGCGCTCGCTCGCTCGCTCGCTCGCGAGCCTCCTGCAAAGATCTATGACATCTCTCCCGAGGTGTAACTCACAGTCGCTTCAGCAACAGGAACCTTATGAAAGTCAAAGTGCTTCGTGCTCGCGCGATCGTCTATGTTTCGCAACTTGTTGCTGGATTGGCTCGGTTGCCGGAGAGATAAAATCATCTTTGCGTATCGCCGGACCGGATTTACCTGGGATTTCACCAAGTGCAGCGAAAATATAATTGGCGGAGTTTTAACAAACGAGCCGTTTGCGTTGTGTGCACTCGGAAACGAAGTAACGGTACGGGTCGTCGCGACTCGTTGATATCTTTGAGACTACGGTTTGTTATGCGGTATCCGTTGCTTTTCCGATGGGAATCTCATGAAATTCAACGAGTGTCGCGATCAAGCCGCATGCAAATTTCCGAGGAAATCAACCGCGAGATTTTTCAAAGCCGAAGTTGTTTCGCGTTCGAAATTTATTTTCAGCGCGTCGCATTCTTTATGAAACGTGGTTGCCGGTTGCCGTTGACGTTGGCCGTACGACGTGATTATTTCCTACTACAGGATGCTCGTGATTGTTGTCATCCGCGTAGGCTGCTTATGATTCATACTACTTCAGCTTATTCCGCGTTATGATTATTATACTTCTGAAAGAGCGGCAGCTCTTTGTCGTGATGATGTGAATAAAAATACATAGTAACTGCTGCTTCTTCTTTTTATGCGAGTTTCTTTTCAATTCGAGATATTGAGGTTATAACATATTATTTTTATAAAAATATATTACTTACAGAATATTTAGTTAAGTTTGAAAAATTATGTGAGCAACTCTTATAATTATTTTAGATCTTTTCGCGACTTAGAGACAAATAATGACGTAATAAAAAATTGTTACGATAAGCCTTTTCAAAATTGAGTCTTTTCACCTCTCGTAAAATATTTATTGCGCATTTTCTACGTAATGCTTAAAGTTTTCCATAAGTATTGGCGAATATGGTCCGTAAATCAGTTTATGCCGCCGATATAATGTAAATAGTACGCGTTATGGCCTTTCGCGAAGAAGTTCATCAATTTTCTTTGAATCCGCCTTGCCTTGTTATAACATCTATCTAATAATGCATGAGTCATTTGAAAATTTTACATTAAATTTTCCGTTTTCGATAAACTTAATTAGTAGAAATCTTTTAAATTAGCACGAGTAAAGAACATATTTAATGCAACGTATTAGGTTTCTTATGCAGCTTTCGATGTACAATAAAGTTTGAACGCGTCGAAAAGATACCAGGTTCAACCTGATTTAAGAGAGTCTCGTATACTTGTATGCTGATGATAAACGTGATTTGCTCAAGTCCTAAGTACAGTTTTCAATGATAGTACGTCAGAAGCAGTGGCACTCGACTGGATTGCCGGCAGTAGTGATGCCTCAACTAGGTCAAACATATTTAGTAGTCAAAGTATTTAGCACGTTTCCTCTCTTATATTTGCCGTATGTCACGATGTGTGCATGTCGCGTATCCGAGTATTGTCACAAATGAAGATCAATACTATGCGCGCAATGAGAACACGGACGAAATACGATTTTACAATGGTACAGATGTGCCCAAATTAATCATTGAATATTTATTATTTCATTGAAACATGATTTGCCATGCATTGCACATATACCATTTCAGTTATTAAGCTAGCAAATTCAGATATTAATTGGCTGTTAAATATACTATTCGCGCGAGTCTCGCTTTCAACCGTGTCAACTAACGCTAATCACGTTTAATTAAATCGTTTGTACTGTGCAGAACCAGCGGTGTTTACAAAAACGATGGCATTAGTTAAAATTAGAGTTTGTCGTTAACGAAATTGGAACTTAATGTTGTACTTTTACAAAGTATGTGCATACGAGCTTTTATCATTTACAAAACATTTGTAAATTATTCATATTATACCAGAATTGCGTAATAGCGTCACAAATTGCATTAGCTCGGGCTATTCATGTACATGTATCCGTCTATCCCTCGTATCTTACTCAATGTAAATTATGACTTCCGTATGAGGCCTATTGAGATGTCTCACACTCCCACGTCAGCGCATGGAATTCGTTACCACTGGTTTTTGTATTAGTATTAGCAGCGCCGCATACACTTGAATAATCTCTGATTACCTTTAACATCCGTATCTTGACGTCGAGAGGAAATTTAATTTCACGCGGCAGCTGGTACCCTGAATCTAACCATATCAACCGCTTCATCCCTTGATGTATTACAAACGCGCAGCCCTTTAGTAGCTTACGGGAAACTCGGAGATGGTGATGGCGAGTATTCGCCAACAGTAAGAATGCAAATATTACACTCGACGAGCATGTCCTATACTGTAATACAATGGCCACGTACGGCCAACGACGAACCATGCAGAAACAAATGTAACGCGATATGCGAGACTGCATTCCTAGGATCCGATATACCGCACTTGATAACGGCTAACGAGGAATCTAAACGCGAATTGAATAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAAaGAGAGAGAGAGAGAGAGAACGAGAGAGAGACAGAGAGCCAGCAAATGGTTAAACGAAACTCTCATATATAGTTTACGTAACGCTAAAACCCAGCATCACAAGGGGATTGTGTAACTTACGTTATACATACTTTTGCGCGGCATTTATCGAGCGAAGCATTACCTAATTCCCATTAGCGTAACTCCTATTTCTAATTTAGTTGATTCACTATGCATTATACTGATTAATGCAAACAATGAAAAGTCGGTAAGACGTTTGCTCTCCATTCAGTTATGAACGTCTGTAATACCGCGATCTGTCTATAATAAGCGAATTTAAAATTCACTTTGATGAAACATTTAAATACATAGGGCAATGTACTTAAACGAAAGTTATCAAATGACATATTGGCACAGATCTATCTATACTTTTTTTtCTTATGACACAATATAATATTTCTACATGGCCTACAAATATCTATTCATTAATATTATTTACTATTGCACAACAGTAAATTATTTTACAAGTAATTTATTAAAATGCATCACCGTGAATTAGAAACTTATTTTCCAAAATTATCCTATACGGATAATACTTGTACAGATAATACATATTTTCTAAATCTTATAGAATCAAAAATTACTCGAAACATTGCACAGAGGCTCAATTTTCGCTCTGTAAAAATGAATTTTTACTTTGCAAAAGTGGATTTTTATTCTTGTTAAAATGACAAATTGCTAGAAAAATTGTTTGATTTTTATTATTTTTAGAGCGACATTTCACTATATGAGGTTTAGAAAGTATAATTTATAGCTTGCAATTTAACCGGTGCTTATGCAGTCGCACAATTAATGTCGATTCGCCGCGATATGCTTCGCTATGTGAAATATATTTCGAAGAGCATAGTTCTAGAAGCGGCTCTTTCCGGTAACGCGGGGAACAGAAATTAATGCAGCTTTGTTCGGGTAGATGCAGAAATTAAGGCCGCTTTGTCCCGGAACGATCGAGTCGTTGGCGACAGCCGAGTCGATCTCGCTCACGAGACGACGCGACGGCGACGTCTGGCGCCGCGAGAGGCACCCGCGGCGCACGCGGGGCATATCCGCGGCGCTCTCTCTCCTCGGCTTGGAATTACTCCCGTCATATTCAAGATCCGGCGCGATACGCCGTGATGGAAATTGTTGGAGAACTTTGCGCGTCGGACGGGGACTTGAAATTCAGTTGTGTTAATTCCTTCGGGTTTTCGGGCGCCCTCCGGGCCAAAGGCCCGGCGCGTTCGTTTCGCGATTAGCGCGTACACTCACCGGTGCGACAAATACTTCCTCCCGCGTGTACGTTTACGCGGTCTGTCGCGAAGGTCGCACCGTTTTACGCGCGTGTGGGTGAACACGGCTCTTTGCAAATCCATTAGCCGGGCTTGCTCGGTCGTTTCCCTTCGGGCGGCCCGACGACGATCGAGAGGAAGAGAGAGAAAGACGGTCGAATGCTCCAATTCCTATTCCGAACTGCTCGAACGACCGGTGCGCGATTAACCAAATACTCCTTGCAATTCAGATTAGTGCTCGTGGAAAATACGCGCCGCAACAATTTCGGTTCGAACATCAACTTCGTCGTTTATATGTCGAATTATGGACGTACCAGCTACGAGCGAGCTTACGATAAGGCGACGGTAGCTTACGATAAGACCTGTGAGCCTTCAGCTATTTGTATTAATTAATAAATGGAAAATATTCAGATGGAAAGATATACTGTTGTTTTACGTGGACTACATGCACGACATTTCTTTACTCAACACTGAAAAAAGGATACCGACTTTGATACCACTCTTGTTTGAGATTATTTACCTTTAATTAATACTTGAGCATTTTTCCATCAAAAGTTTTCTTATTTTTTtATTTTGCAATCCCTTTTGTGAGAATTGTGAGAAGATTATACCGTCTACATCTGGCAAAAGAGAATGTATCGACAAAGCGAAGAATAAGAAAAAACAGGGCTATTGATGATTGAGGTGCCGTTGAGAATTAATAGCGAAGACGGGTAAAATGAAATTGACAGCAATTGGAGTAAGCCAACCGCAGTCCGGTTATGGCCGCAGTAAAGTTTTAGTGCGTCAGTAAAACTTTTATTTACGCGCATCCCTCTGTCGTTTTATCGCTGTAAGAATATTTTGCTAATTGGAATCATCTTATCTGGGTGATCTTTTCGCTTTATCGTTATCGTAGTAAAATTGCAATTCCACTTTTATATTGCCCAGGAGAAATATCGAAAGCACTCACGCTAGCGAGTCCAAATCTACGTTTCTTTTCCTTTCTCCGCCTGCAACGCTTAGTTTTAGCGTACACGTTACACTTACCTGAAACAAAAATAAAATGGAATTAAGATTGACATTGTAGAAATGTGATATAAAAATCATTTTTTTTATAAGCAATTATTTTAGAAGGATTAAAATTATAAGAGACGCTCCGTTTTTAATTCGTCAATTTTTTAACGAATTACAAGAATTGTCGTAGAGGTCAACTATGTGTATATTGGCAAAATGTCGCACCCTCATCAGAGAGTTGTAGTCTGCAAAAATAGCCACTGACTTGTTACAGAGATCTCTCTTATTAACGTTCATGAAATTCACCAACAATGAAATTATGCAAACACCGCTTATTCATAGTATATTTGATCGGATTAATTATATATATTTGTGAACTCGCGAAGGCAACTTTGTTGGTTGGCTGGAGTCTGAATGCGGTGAAACGCGTCGAACTAACTTGCACGTTACATATTGATTGCCCGACCAGTCTACGTGTATGAGTTTCCTGCAAACTTATTCGACGCCAAATAGTATTCAACAGGTTTTCGTGTATCGCGTGTAAATGCTAGTTTGTTCATGTTTCGCGAACTGTTGATATCAGTGTGAATGTTGCGTCTCGTTGTTAGCTTTATTAAAACAGAACTAACGAGGGACGCCTGAGTATTTGCATATTCATTGTGCTCCTGTAACTCGTGTAATGGTATTTCCGTGCGTTACTTATATCGGCATTATTTTTTCTTGCACTCGATCATTCGTTAGTTATTGAACTGGCTCGTTATAACTTTAGAAACGTTTGTGAAAAGTTATCTTCATTTTCTGAGCGGTGAGATGAAGTTTCACTGGAAATAAAAATCTATCGTACATTTAAACAAGTCTATCCGGACTTTGTGTAGGCTAATTGAATGAATTTATTTATTCCAAAGATAATTAAAAATATACCTTTGATTCTTATGATTTTTTTTTtGAGCAATCAAGCAATAAATTTAATGGAATGTAATAGTAGAATGCTTCTATGTAACTGTATTTTTTAATATGACACAGAATATTTGCCATATTTCCTGTAAAAGAATTTAAATTAAACGCTGCTTTCCTAAAATTTCTGATTCATCGTTATCTGCATAAATTCCGTCATTTATGTTGTGTTCTAGATGAACTTTATGTATATGTATATTTTAAACTAATCAAAAAATTTAGAAAACTAATTTGGGTCGACAATTTCCATTTATTCTCCTCTTTGGCCCTTCTATGTGAATTACTCCAATCCTCAAACCCCCCTCGGGAAACCGCAATATTTGAGAGCAACCATTGGAATTCAAAAGATATCGTTGCTTGACGAACGATGAATAAATACCGCATAAATCACGGCGTCACTCAGAAGACGTCAACAGCGTTGAAATAATCGTTATCGGCTACCGACAGCGTGCAACGCCCGACAATGAGACGTTGTCTCCGATCTGATTGGCGCTGGCAGAGAAACGATGCACACGCGCCTATCACGATATATCAGCCTGTTTACCCAGCAGTTAACGAGTATAGCTCGGCGACGATACGGTCCGCGCGCCGTGAACGCATTATCCGATGAATGAAGCACCAATCTCACCCCCGGATCTCGAAACGCAAGCAGGCAGCGGGCGAACAGTCGTCGGACATACAGCACTCTCCAAGGCCTACGCCTTGGAAACTTATCGCCCCCATAGGCTGCAAGTGCTGCAAGTGCGAGAGGCATTTGCATTTCATGAGCATGAGAGTCCGGTGCTCGTGGTTGAAAAGTAAGGAATTCGTCTAACGCTTGTCTAACCGAGTGATTTATGCAGCGTGGGTTATTTTTAGATCTGATATATCATTTTAAATCGTCGACAAACGGGACGAATAAGAAGGAAAGATTAATATCCGGAAACGTTTCCTCGTCCCCGTGTTTATTCGGAAAATGTGCGAGTGCATTCTCTGGGGCAGCGTTCATAAAAATTCTTTTTTTTTATCTGTTTCGTTAATGAAGCCAAGTATTTCTTGCGTCACGTCAATCGCTTTAGGAGAGGGTGATTCCTTCTTAAGATTTCGCGAGATGGTGCGCCGAGATTATTTTATTATAGCATGCAATTATTTTATATGAGCGACGCACATACCATGTTTTATAAAAAaTAAATATCGTTGTCCCAGATCTCCAAATCTGAGCAGTGTCCCGATGCGGGGTCACCGATTTGCAAAACTTCCGTGGCAGTATGAAATTAAAGCCTCGTACATGTACAACCGCTGCACCGCTTCAATTCTCTTTAAGCGAGATATAAATCTGCGCCTGAAGTGTCCTTTATGCTCTTTACAAAGGTCCCTATAGTTCATCGTGTGAGCGAGCTAAGAAATTAATCTGTTTCAACGTAGCTCTCTAGAAAATTCCGACATAGTCGATACATCAGAGGATTAAGCCATGTCTGCGGTATTAATGTAATTTATATTTGCATAGCGTACATGTACGCAGATCTAAAACGTACTTGCCCGGGTCTAGAGCAAACGTACCGCATAAATATTGTGATAAATTCAGCGAGCGCTGCTCTCGGAGAGCTTCGTGTAGCTCGAAACCACACTTAGATTAGATACGCCCGTTTATGAAGACCGCCTGATCGTTGACGAAATTCCATTCCGGTCAGAGATGACGCATCACGGACCGTGAGCTCGACCGCGCGAGATCGGATCACGGGTAAGGACACCTTCCTGCGGTCGTCCGACGAAGTTCCGTGCGGGCGATTACCGGATCGTTTCGAGAGACGGAGACAGATAGAAAGAGAGAAAGAGAGAGAAGGAGAACATGCTCCTCGCCTCGATATATCGGCGCGACTATTTAGCGCCGCTAACGAGTGCAGGGTACCGCCGTCGTACCGACGATCTACACGTATGGCGCGTTATCCCATGAATGGAGCTTGCAATCTCGTCTCTGGATCTCCCACCGTGGCCGGCGGGGCCAGCGAAGTGAACAGTTGGCCGACGTCGGAGAGCCTGCTCCACTCGCGGCAATGCGAGCTACCGTTTGAGATTAGCATCTTTTATGCATATACATGGGAGACCTGCAGGCGGACAGGCGCGGGCACGCGGGCGCACGGGAGCGCGGACGCGCGCACGACTACCCAATTCCGCCTCGCAGCGAGAAGGAGGTTTATCTACGTACGTACGGTGAATGCACACAGCCGCGGTGCATTCGCGGAGGGCCAGAAGCTCGATCTCCCTCTTTCTTGGCTCTCGGTTCTGTCACGACCTCGCTTACGCCTGTCGAGCTCTTCTCGTGCCGACATCATCGTACCATGGTCCCGTGCATCCTCGGTCTTTATGCCGCTCCGTGCCTTTGGGAAGTGGCCTCCGATCTTATCTCGCGACTCGTCTCCTTCGAAGCGGATCCCCTCCGTTTAAGTTCCACAGCTGCGCCTCGCGCTCACTCAATCGCGTTCTCGTGGAACTGCAGCAGCCCCGCGTAGAACGCATGCGACTCGACGCGGGATACCTTTCGGGTGACACTCGGAGGGTGATGGGATAATTACACGGGTCTCTCCCCAGGGGAAAACTTGTCGTCGCGCTCGCTCGCGAAAGGAATCGTCAAAAGCTCGGCCGTAGCTGACACATCGTGCGCGCTAATGACGGTCGATCGCGTTCCCTGCGATTAATTATTAAACGATTAGTCGCTAACTAGAATGACGCTTGGGAATTGAGATTCCCGAGAGTGGGTGCTCCCATGAAATATGTATATTTGAAAACATTGGATATTCATTACGTTTGGGTAAGCGTCAGATTTGAATAATAAGTAGCGCTTAATTTTTCTTGTTAAAAAAAAaCCAACATTCTCTACCATGTAAATTCTTATATTAAATTCGCGCGAAATTCATGAATGCTTAGAGGTATATACGACAGAAGAAATTGAATAATTTTGGGCGATACAATCTGCATTATACGATGAAATTGAAAGCCACAATTTGACTTTCATTACTGCCATTCATTCACAGTTGCGAAAGCGATTATATATCGTCCGCAATAAGGCCTAAGAGCGTTCCTTATTAAAATGCAATTATTCCGGCGCGTATCCAGCATTGTTAACCGGCGTTGCGTGCGAGCACTTGCCCACTGCGAAAATGATTTGTAGGACTGTGCCTATGATCGACCATGTACTCTATCGATAAAGGATCGCGTGGGCGATCGAAGGCACTTTCCAGACACCTTTGGTGTTGGAATAATTGCGCCGAACACCGGGGAAATAGGCGTTAAGCGTGGGAGGCTAGCGAAGTAGACGGCAGCAACTCGTTTTCTAGATTACTGCTCCATTCATAAATTTGTATGCGATTCAACAACGAGTTTCTCATTTTCACTTTTGAGATTCAACTCGGAAAAACAACTGAAAAAATTTTCCGATAAACTACAATTAAAGTGAAATTGCACGCTTTATATGAGTAGGGGAAGGTGAACAAGACAGTGTGATGAAGTATCCCTTGTATCGCGCGATTCGAATGCAAGAATCATAATCGAACATACGCGTTAGTTGCTCACGAGCCAGCAAAATAGACTGCGCTATTAAGTTAGACTATAATTTATTTTTTTTTTGCAATTTCTTTATGATTTTCTCTCATTTTTTTACTTCTGACATTAGTATTAAATTATAGCATAACTTTTAAAGTGTATCCCATTTTGCTCACGAGAATATCCCGTCTTACTCGACCCGTGGGGCAAGATGGGAAGAAATGCCTTTTTCAATTTTTTTAAAATTGACTTTTAAAAATTCATAATTCTTTGAAGATTTTATTTAATGATAGTTATATTGAAAAATTAATATCCAAAGAATATTTAAGAAGTAGAGATAATTCGTTGATTATAAAAACCTAATTTTTCATAATCATCATCAAACTTTAACTACATCGTTTTCTTCATCTTTCTCTGCGTACAGAAAATGTCTTTCTGATCTCAATTTACTTAATTTACTGAAGGTAAAATATCACAACATATTGACCGCGTGAAAATTGACGTAGACTATTAGACTGCTTATTTGAACGTTGAACAGAAAGGAATAGAATACAAAGAACGATGAGATTGAACGACACATTTTTGCATTTCGATTTAGCGCTGTTTATGCGTTCATAAAATACCGATGATGATAACAAGAATGCATTTCGTTGTTTGCCAGGCGATATTAACAATACATCTGTATCTTTATGCGGCACATGAGAGCGTTTATATAAAAATGCACTTGCGCGCAAGCCGCGATTATCTCGCTCGAAGTGCGCCTTACGGACAGTATTGTCGGGTACTGAAATTTGTACGTACGACAGTACGACGACATTCGCGTGCTTGAAAATATGAAAGTTTTTCCACACCGCGCTCAGACGCACACAGGTCACTGCCGTAATCGTATTCACGGTATTCACGTCGTTCTGGGACGAACTTTGAATACCGGTTTTCCGTTTCTCGACATGCGCCGACTGTGAGCCAATTTATATGCAAAATTATCTCGCGCGGTAACACATGTTCAAAAGGCATGGACGACCATAAAAAaTTACATTATCACATCGTCACGCGCAAAATTTGTATGCAAAAGCGTATGAACGCGATATCGTGCCCACGGATAGGAAGCATCGCGCGTACCGAAAAACGCTGCATTTATTCATGTCCATCTTTCTTTCTCAAGGTCGACCGAAATATTCAGACGGCATAAAAATCCGCGACGAACTCGGATGCGCGTCTTAAGCCCGATCGGAGAGCGCACGGCGACGTGCCACAGGCGTATTACACGCATGGGCGATATATGTCAAATTACATTTACACACACTGTCACACCCGTCGCTTCGTACCAACTTTTtTTTTtATGCATTCGTAATTACCCCATCGCGCGTTCTACCGTAATCACATGGAAATTGGTGACGTAATTAGAAATATACTAGAAAGAAAATGCGACGCTAATAATTGCGTCCCGTAATTAATCCTGCGATCCCAATGTAGACATCAAAGCGACAAGAGTCGCAGTCCCGAATATGCGTCGCTTGATTGATTTGTCAAAGCGGATCGCAATTATTTTCGGCATTCGATTCATCGAACCCCCATCATGCCATTCGCGCCCACCTTTCGTAAAAGTACCACTTGAACGAAACCGATTCGCGCGATAATATGACACTGTGTGTTTGGGTGTATAGGTCTCTAAGACCTGGAATCATTAAACCATTTTGTAATAAAATGACGTCACGTCCGCATCGTAAAACTGAGTCGATGTGTTCTAATTGAATCTGATTTTTGTAACAGTTCTAATTAGTTCTGCTATTTTATTTACAAAGTTTGATTCAGCCAATACGCGTGAATCCGGTTGCCAGTGGCCAGACTCTCATTTCTAAGGACTCGAGACAGTTTGCACCGCCTCGCGACTACGCAACGCTAAAACCAGTAAATAACAATTTTTCTCGCCGTTAGATAAATAATCATTTCGAAGGAATCTATTCGCCGTAGCCCGTCGTTACTTACGCAACGCTGTTTTCCGCGACACAAATTGTTAGGCTTGTCCAAACACACTTTCTATTGTATACGTTCGCGGCTAAACGGTCGACAGACATTATTTCGATGTTACGTTCGCATCGAGTTCGCACTTGTGAAAATCACTCGTTAAATTATGTATCCGCGAAGAAGGTACGAAAGTTTGCCGTCGACGAAAGTAATTCTGTCGCGGCGCAACAACGCGAAGACGGGCGGCGTGGCGGCGGCGGCGTGGCGGCGACGTTATGTAAATGAGCCAGCTTTATTAAACGAATCGACAGGATCGAGCGAAACGAGCCGCCCGTACTCGCCGTTCGTTTGTTCATTTTTCGGTGGAATCGCAAAAATAGCGGGATTATGCAAATACGGCGTTTATCCGTCCCGGACCCGGCAGCACTCGTCGATCTTCCACGGTCGTTATAACGCGAAGATGTTCAAGCAAACGTCGCGAAAATCGCACTCGTTAATCTCCCGGGGCGTTCTTATCGGTCTGGCGTTATGAATTAAAGCCAGTCGCCGTCGGGGCGCAACCGGCCGGCGCAAGAGTTTAAATAACGAATGTGATCACGTAATAACAGGTCGATCGGCTTCTGTCGCAGTATAAACTTCGTGCGCGTAGTCGCACGTTTGTTATCCACGTAGATGAAAAAGCGTTTCGGAGGAGAGAACCTGTCTCTGCGCGGGCGTATCGAGGAAAGAGATCGCTTTTGCCCGCGATAGATTTATGCGCCTCATTATTATTTGTGCTCCTTCTCACCGAGAAAATGTAATAATGTGGCAATATTGTTATCGTCGCTACATCAGACTTATGGTTTTCGGCTCTACATTTTGCATAACTAGTTTGCATAATCGTATAATAAATCGTTGTATGTACGACAGTGCGTAGCACTCGTATTAACAGAAACTTTGAATTAGCCCGATAGAAAATTGGGTCCAGACAGCAAATTACCGTAATTAGCGTTGTGTCTGATCTCACTTGAATTTATTACGTCTATGTTTTATTACATATGTCAAAGGCATTCCAGTATCTAAACGCAGATGTAAGTACCACCGGAATTTCCGCTTAAATGGCTACGAGGTAAACCATTCAGCATAAAGAGATACAGCATAAAGCGATAGACTGAAGGTATATTGTCTTAAAGCGAATCATCATATTCTGTAGAGAAAGAGAGAAATTTACGAATAAAAGCCTCGTAATATTTAACATAAATTGCGACGATATAGATAAATATATTTACGAATCTGAAATGTAACGAGATTATTTTTTACAATTTAAATCGCGAGATTATCTTATATATTGAAAATAACTGAGAACGTGTCACATAAATGTGCACGTTTATGATATAATTTTATTATTTATGTCATCGTTGAAAAATTCAATTTTTCTATGTAAAGAAATTTTCCCTGTTTAAATCTTAAGCGATTCACGTTTGTCTTAAGCTTAAAACGATTTTTTGCAAAAATACGTTTTAAAAAAAATGCAATAAATATATTAGATAATATTACATTCGAAAGGCGGAATTATATATTGACTGTTTCTCTCTGTTTTGCCAGATTTAATTCTGTTTCATATCAATAAAATGATAATTCGTATGAAGAGCCATCGACCTATGAACGTTTTATGAATATTCATTGTATTACATATCGCTACAATATTTTCACAAGTACTCGAAAATTTAAAAAATGCCTGTAATTCGCGCAATATATTCAAATATGATGGGTCGGCGATACGCGGCGTAAAATCGGAAAAGAGATTAGATGCGAAAGAAATTGATATGCGTAAGTTAGAAAAATTAGAGGGATCGTTCGGGAAAAAAAATTTGGGAGCGCGCGATCGGAGCAGCCCATCGTAGGTGAACGGCATTGAGTCGTACGCGATCACGAGAAGCTGTCAACTCGATAAAACGTCAGCGTAATCAAATCGCGGGAGCTGAAAACGTCAGGCGGCGACGTATCGCCGCGTTTCGGGGGTCCAATCAAGGTGGCATTGAATGCGTTTGTTACGATGCCTCGCTCGGCTCGCCCCACAACCGGGATAAGTGCATTATCGGGGCCCACGAATGCCGGCAACATGCACACACACACGTTACGAGAGACGTGCGCGGGCGTACGAATGAACGCTCGAATGGAAAATCCATAGGCACTGCCGCTGTTCTCGCGCGTATTCTGCGATTCTAATGAGGCGTACAGTCGTCGTCATTTGCCGAGATTGGCGCGAAGGGGGCGGGCAGCGACGGAGCAAAAGGAAGACCGGGATCAGGCTCCATGAGAGAGAATTCAATCCCGTAAAGTCGCGGCATAATAAGCAATTACTACCGTTCCGTAGGAATTGCGCGTGGCGCGCCACCGGGGTGGAAACTGCATTTGCGGAATCTCGATTAAATACATGTTACATACCATTAACCCTTTCAACCTGGTAGCATTGAAGCGTGTACGGAATTCTGCGTTATAATCATCGTGGTGTTCCTACGAAGGTTGATGCTATTCAAACCGAATTTGAGATTATGAGAGAAATTGTATACAATTATGAAAAATTGAATTTCAGAATATTTACGGTTTACAGCCAATATCCCGGAAATTAACGATTTATATAATCAATATTGTGTATTCAATAACAATAAGCATTGTTTAATTATGCAAAATTAAAATTAAATCAAAATTTTCAGTCACTAATAAAATATAAACGATGCGAAAAGGCAAAATTCATTTATATGTATTACAATATGCGAATAATATGAAATAATTATTATAGATTATGATGTGCACAAAGAAAAGACGTAATTTTCATCTGACTCTCGCTGAAATGTAATAATTGTAATCCTCTGTAAAAGTTACGGTAATATGAAGATTATACGAAAGCTTTGAGCTCGCAATCTCTCGCAAAAAAAaGAATAACGAGGCTTAGTTTCTCCTTTGTGATCGATCCATTCATTTCATACGCGTTATATCGCGCGACATCGCGATACATCTACGATCGAGGTTGCGGAGATATCGACATGGTAACATCATCGATACCATTGAAACTCGATACTCTTGTTCGTTGAACAGAACGATCTCTGAAAAACTCAGCTATCATTGATATCCCTACAGCTGTATCGTGCTTGCGTTAATAACGAGGAGCGCTTGGTTGGGAAAAAAATAACGAGAACGCGTATATGGGCGCGCGTAATACGAGCCTGACTCTAACACGGAGATTCGCAAAATCTGTCTTCGGCGAACGTCGAAATAAATCACTTGGGAACAATGGTGCATCAGTTACTTGATCCGAAAGTATATTATTCTCTGAACTCGTAATTTTTTTAAACGCACTACAAATTTTTCATACAAGATGTACTCGTAAATTTCGTCGGTAATGTTTAAAACATAAAGACATAATAAATTTTAACCAATTTTGATTTATTCATTCATAAAAATGTCAGATCGCAAATATTAACGAATATTTCAATATAATCTCTTTTTCATGGAAATTTAAAGTTAAATTTGAATATGTGTGCTCACGTTTAATTTGACCGTGTGCATGTGCCACTTAATTATTATCGATGATATATATTTTAGATACATTTAATGATATTACAAGGATTATGATTGTATTCTGCTTTTTATCGTAACTACAGATTTAATTACTTAAGTTTAACAATACTTGCTTTAATTATTTATCACTCATGTCAGCTAACACGAGTCTCGGTGAAACAGACATCAATTTTAAACGGACACGGGAATTAGCTGAGTTTCCTCTAGCACTAAAGAAGTTTGACGAATCGCCATACTTCCTTCGCAAACTTTTAAATCGCGTCGCTTTATGCCCAAGTCTTGTACCGTCTTTCGAAATTTAAAGTCTGCCCGTCGTATTCCGGGTGGGTAAGGCGAGAATTTACAGCCGGGTTTGGCAATGCGCACGTATGTGTATAAGTCTGAAATATGCTTCGAAGCTTATCCAATGTCACAGTCACCCAAGAAACATGCGTGCGAAGCAATAACGCGCTCCGTCTCTCTCTCTTTTTCGTTCGTGCCTTTCGATAACCTGCCGCCCGTAGATGCTGCCACCCTGCTGGTAGATTACGAAAGCAATTCGCTTCGGTTTTGCTGTTATTTCATAACATAAATGTCCGATGCATTCATGAATTTCTTTCACCATCATTAAGTAAGATGATGGAAAAAAaTGGAATTGATTGAACGACTCTGATACATCGTATGAAAGAAAACTTTTCGGAATACTTATCAGATTGTGTCTAATATAAAAGCAATTATCTAAATGTAAATTCTATGTATTTTATAATTGAATTACTATTTACTGAATGTATGAATTGTGTTTTTAATTCTCAATATTAAACATTTTGAAAAATCAGCCTCTCAATATGATTTTACAAATTGATAAAATTTGTAATACAGTAATTTATATTATTTCATCATGGAACTTAAAATTTTAATTTATCAAATTTACGTTTATCAGAGAATATCTGTAATTAAGTTAATCTAGAAGTTTTCGCGCTTAGAAAAAaTTTTCTTTTACGGTTGGTGCATTATACACAACGATGCGTGAAACGACACGCGTACGCGTGCACATCCCGAGTTAGTTAATGTACCACATTAACGTAATGAACTTTTCCCCCTTCTCGCGAGAAGGAGAGAAATATCTCCGAATTACATGAATCGATATGCATCTGTGCCCGGGTCATAAATCAATAAATTCTTAACCCTCCTTCCGAGCGTCGACAAACAAAACACCCCGTTCCCGGTTCTCGGCGCATATCTACACATAGTACACACAAGCATATACCCATCCCCGATGGCTTCTCGGAGGCTGAATATGGCCTTAAGCAGCCGTTTTTTACTCGCGTTAAAATGCACCCCTGGCAGGGAGCTATGGCGCCCGAGCGGCGACAGCCACCCTCACCTCCGGGTCGACTCGGCCCCATGCCGTGTACCGTAGGACGGGGGCACCAGATAATTCTGTTTTAGTTTCGCATTACAACGCGAGGCACGGCAGCGAGACGGACTTCTCGTCCCATCAGGGCGACACCCTTCGCTCCTCGTAACTTCGTCCCCTTTTtCACTTTCTTAGGCGATCGCTCTGGGGCACCAaGGAAAAAAAaTTTGTTCTTTCTCTTTTTAACATTATTCTTCGCTCGCTTTGTCTCGAGCACGTTTTCTCACGTTATGCACCCTTGTCTCCTTATCCTTCTCACCCCTGCTTCTCTCACGACGCGACGGACACGAAAGTACCTGCGAGAGGTAGCTGCCGAATAAGAATTTGACTAATGCAATCGCGGATGCTAAGAAGCCACTCTCGTCGGCTATTGTGCCATGTTATCTCCTTACTTTTACTCCCTATACTTTCCTCTTCTTTGCCCCTACGGCAAATAGAAGAGGACAGAATGGGGAGGCAACCCTGTGAAGGACATTTTGTCAAAGTATACTTGTGCATTTTGTTGGAAGATGTGGAGCGTTGTGAGGGGAATAAAATTTAAGTGTTTACATTGAATGACAATTGTTTCGGGAAGATAATATATTTTTTCTTATGTAGGTTACTTTTAGATTTTCTTATATACATGATTTGTTGTGATTTTTCTTTGCGTTGTTACTACGTGAAATTAATGAATCAGTATCTTATCCGAGTACTATTAAATATTTTACGTTTTAAATGTGAATGTTAATAAACAATTCAATTTTATAATTATCAAAATTACTAAATTTATTCTTGCATGCCGATGAAGTGCGCTTAACTTGCTTCCGTGCAGAGTTAAATTGGTGTGCGCTAAATAACTGATTCACACAACGGCTTCTACAATAGTTCGCTGAAAGGATTCCCTCTCGATTTCTGACCTCGAGATGGCATTAAACTGAATTCCACGTTCGCCGGAGCACATTCCATGGCCCATCCCGAAAAGCGAAACTCGCTTTTAGTAGGTACGCGAGACAGACGGAAGCAATTTCGAGTTTACGCCTCGACAAGCCCTAGCGCAAGTCGCACATCTCATTTTGCAGTAGTCAAATGTTTCCTCGCATAATATGCGTCTCCGTGACGCTGTTGCAAGACGACGACTCGCAAAAATTGCGCTACGCGTCGCGTCCAAAAGTTAAATCTTTGACGATCGTTAAACGAACTACGTGCGAATTTGTTACTCGTTTGAAGAGTCGGACGAAGTAAATCTCTGACAGGCAGCGTGATGCATTCCGGCGATTCGTCCAAACGCGAATTGTCTACCCATCGGCGGACAGGAATCGATCACAAACAAACAACGAATGGTCGACTGCGTTTTAAATATCGCAGCTCCGAATCCTCTTTTGACAGCTCGCGAGAATCTGAAACCATCGCACACTATTCTCCGTTTGCGTTATGTGCACGTGCATTCGCAGGCAGAAATGTCCATCGGTTTTAGATTCCTCCGTGTGTATAGCGAGAAACAATCGAAAGACCGAAATAATAGCCGCCGGTCGTCGAAAGTGAAACGGTCTGTGCAGTTGTGTAATAGGAAAATCGTAGTTTATGGCGCTGCATTGTTGGTTTCTGTCGTCGCGGTTACATGCCTTAAATAACTGCCGAACCGGGCCCACGTAAGCATCAAGTATAAACCGTCTTTCTTCGATTTCTGACCCCGGCTTGAAATTAATCTGGATTCCGCGTACACCGGCACGCGGCGCGATTTCGCCGTGTTGCACCGCGGCGATATTTCGCATGTGGTCGATACGTGCGGCAAATGGAACCAATCCCAACTTTTATCCCGATAAATCGTGGCGCAAAATACTGCTCCTACCGTCGTGCAAAACGCAAATTTCACTGCTGACTACGACGATGTTTCTTGTCTAAAGTGACACACCCAGAATGAGGCAGTAAATCTCGAATTACGTAAATGAGAATGCATGTCTTTTATAAATCTCAGCAGTTGCCTTTTTTTtCAAGACTATTTCTATCGCATTTTTCTTTTACAAAAATTATAAGTTATAAGTTCTTTAAAATTCAGAAATATTAATTAACATGATAATTATTAATAAATATTACAATGACTTTTAATTAATTTGTTTAATTGATTCAGTTGTTTTAATTTGTATAGTTATAACAGTTACATGTCATTATAATACGGTATTTTTAATACATAAATATAAATTCAAAAGTATTATATTATATTAATACAAAAACACTGAAATATTTCCTGAGGCTATAAGCTATTTTTtAATTAATTATATTTATTTAAAAAaCTTCTTATATATATTATATTCATACAATTTTATTTCTCTTGAAGAAAAATGAGGAAAAGAGTGACGTTTAATTTACATAAATAATTCCTCGATCAAAAGTAATGTAAACAGGATGTTTACTACCGGGAAAAACCGGGAAAACATGGGATTTTCAGGAAGTTTATTTTTTATCCTTGAAAATCATGAATGTTCATGAGTACTATGGAAAAATTTTGGAATTTTACTTTTAATATTCTGCTTTTAAAGTTAAATTCTATCTTTTTCTGACGAAATTGTTTCTTTGATCATTTTTTCTTGATAATGCAAGGTTAATTAGTAATATATAGTAATATGGCATGCATGCTCATGTACGACATTCTCGACTTGCAAGTTTTTATAAAAAGAAATTAATGACAATAGAAGACAATACATCATTCTAAATTAGCATTGTGAGTTTAATGATTGTGAACTAGATCCGTATATTGCGGGCAGATCGATATATACCACATTTAGTTCATATTATTTCTTTTTACTACAGTCTCATATTTAAAGTTTAAAACCTTAAGTAGCTTTTCTTTGTAATTGTATGATGAAGGATTATTAAAAATTATAACAAAATTTATTTCAAAGCTGCATTAAAAAGTTCTTTAATCTAATTTAAAATTTGGAATAAAATTCCTGGAAAATCCGGTAATTTTCGGGTAATTTTTTTTCTCAAAACTTGAATAAACACTCTGGTATTTTTCTTTCTGGAGAAATTTTTTCGAAATTTTAATGCAAATTATTTGGAAGAGCTAGAATCAGAATATTCTGTACAAATTTATTTCATAAAGTTCTAAATATTTAACATGGACGGTAATAACGACAACGTTTTAAGGCGATAATATAACGGTTAGCGTATGACCTTGGTGTTTGTTGTTACAGCGTACAGTGTCGGTGCGCAAACAAGGCCGTTCCGCGCCGTGTTATTCGCGCTACGAGATTCAAGCCGGCAGGTAGTAGCATGGGTTGCTGCGCGTGTCACCATGTCATTATCCTACGAAACGTGATAATTCTCAACGAACAATTAGCGCGATTATCAACCCGTACGTTAATTAGCTTTATAATTGACAATTCGTTAGCATGTCAAAGCAATATGTTATATATCGAAGCAAATATTTTGCGCTATTTATTTATTTTATATAAGTTTCAAAAAGATAGAAGATGAACACTGTAAATTACTGTCCGTTATTTATGGATAATAATTATCTGATTAATGATTTATTTCGCTTTGACTCAGGTAATTCATCTCGCATTACGCTTTAAATTTCGGATACGTGGTATGTCCATTATCATTTTTTGAAGATTGAGGGAATGGAGTAATATTTGAATAATCGGATCGAATGATTGTAGTTATGGAAAATAGTTGATCTTTCATTACTAATTCCACAGGATTGCGTGTCGCGTATAGTTAATATCAAGAGTGTCATAGTGATACAGACAATCGCGTGACCATCGATAATCAGTTTGCGTTTCACACGTTTTTGCGAATGTCGGTTGCGTGAATGCAACGAAGAAGTATTTGAGAGAAGGAGATCTCGAGGAAACATTGGGAGACGGTAGAGCGATCAGTAATTACAATGAGGTATATCATCTTATTGATTCATTGATTCGGAATAGACGAGTTAGAACAGATTAGCGCGTTGAACCTTCAGACGTGTGTAATCGCTCGCGACTATATTGTGCATACAAGCAAGAATGCACACATACGAAGCCCATACGATAAAGCTCATTGCTATCGATGCATTATGGACCGGTTTAATTATTATTGACACATTTCAGTGTAATATTAATTAGCGGAATAGTAATTATGATATGTGCATTATTTGAAGTTTATAATAAATTTAAACTTGCAACGTACAATACATAATATGTACACATATGTTACAAAGAAATTGTATGTGATTGATGTTCAGTGCTCATTTTTTGCTATATACCAATAATTACTGATTCTTTGTCGATTACAATCTCTGAGCTTCGCATGTGCACATTCTTGTACGTACAATATAGTTCCGAACGATTACACACGTTTGAAGGTTCAACGCGCTAATCTGTTCTAATTCATCTATTCTGAGTCAAAGGATCAGTAAGATAATATACCTCACTGTAATTACTTATCTCATGACTACGAATTTCGAATGGAGGAGGAGATCAGTATTCTGAAAGGCTCAGTGATGAACGTAACGATTGGGGAAGGATGGGGTACGCGCGTGTCGTCGATTTAATTAAACAAATCGATTCGTCGCGTTGCATGTTAAATTGGGAGTGCTATACAAAGTATCGCGCGATCGTAATTACTTGTTGTGTCTTACGGGAGTTACGAAATTGATAATCTAATTGTAATCAAAGTTTTACGTTAGTTATGTTAGTTATGTTTATGTGATTTCGAAAACATATTCATGATGCATGATATTTAATTTTGATACAAACAATGCATATGAGTGCTATGAAGTATGAATAATAAACAAAAAATTTTTATAAAACTTTTTTAAATTGCAGATTGATCCGTTTATATCGGAAGAAATTTTAGTACAAATCTAAAATTGAAAAAGTATTTTGGTCCGCGTATATTCCACAGGAATCACTGATCCGCACAGTCATTTGGGCTTAGCAGATCCACGGATCCGAACTCAACACATTGCGGATACTCATATCACCTACATGTATATATACACTATATACACGTATAGATATGTACACTTACACACACACGCGTTTTTATGAGCGATAGTTCGATGATAGGTGAAGAGAAGTAAAACATGACTCATAAAaCATGAACCTAAAATGAATCTAAAGTGAATAGTTGAAGAAGTACAATATAACTTAATCTAAAGAGAAGAATAAGTTGAAATTTTAGGTATATATATTCAAAAACTTTGTTAAGTTAGAAATATATATATATTACAAAAAAaTATTTTATTTTAACTATTTATATTTAAAATTAAATTTAATCAAATTTAGCTTAATTACATTTTGTATAGATGTAAAAGAATAAGATTTCATTTTTCTGGTATAAGATGATAAAAAAAATGTGACAAAACCAACATCAGAAATACCGTGTATACTTTATTATTTCATGTGGTCGTAATATTTTAATCAATGTCTGGGACCATAATTAATCTTCAAGTTTAATTTTAAGTCAAAGAATATTTTTAATTTATCGAAATTATGTAATTTTAATTCCTTCGAAATATCAGAAATTTGATATAAAAATAATCAAATGCATATATATCGCATGAAATAGACTAGATTCGTCATTAGCTAACAATAAGCACGTGAGAGTGATCTCAAATGTCGTCTTATGCGTCCCATTCCGTCGCATCCGAGCCTGTTTCTAGCATTGGGTGTCGTTCGGGAGACACTCCTTCCGCAATGCGGCCTGCGAAGGGTGTGCAGTCCGGGTAGAGAGGGTGGTTAATCCATCCCCCGCCGTGAGTCACGCGCCGGCATGGAATTTACGAGGCGCAGTGTCGTCGTCGCGCCTTGGCTCCTCTGATCCGTAGGATTATCTCTCTCGGACTGCGCCTGGTCCCCATGCGTTGCGGCCCACTGACGCCCGATTATTATGCGATCAAAATGTGGCGCCTAGTTAGAAGACCCCTTAATTATAAGGGGCTGATCGAGCCAATAGATCCGGCCAAATGTACCCCTGACGTAGTTATACATTACGTATACCCAAAAGGGCGATATTCTTCGCGTATGCGCAACCTGCCGTACGCCGGAATTACTCGGGCTCGTACGCGGCTTATCGGAACTAATAAGTTTGCCGGGGAATTCTCTGCTGCATACAAGGAAGAACTTGTTGGGACGTTAGCGCGCGAACATATGCAGAGAGTTTCCTCTCATCACAGATTCCTACGTCTCGATATGATTGATTCAGCACGCGGCGCAAGTCACGGATATCGCGATTGTGTACACGCGCTTGTAACACGGTTGACTCGATCAACTGAATTCAGGTATGTTGACTCAGCGAGATTTGACACACGTGTCAAGATACGCATACATCATTCGCTGTACCTTGATATATATGTCAAGGTGTGACGTCTCGTTAACTCGATAACATCATTCCAGTCAATTGTTGAAATTATCCCGGCTAATAATCAGCGTCATAGAATTGTATAATTACCTCCGCCAAGGAGATTCTATGGTTCGTTTGTTGTGCACTTCGCAGCCTTGTTAACGACGTCACAATACGACAACGTAATGTATCCGGCAAACTTGTTCTTTCTTTCATGTCAATTATTAGGTTTATTGTTAGAAAATTATTACTCTATTCTGCTTATTAAATAACTCTCGTATGCTGTCACTTAACTTAGTACATTGAAAAAAAGAGTTTGATAATAATAAAGCTTTGATGGATTAATTCCAATTAAATTCTCAATTATTTTGACTAAATATTTAGCAACTATGTTAAGCAACTAAACATAATAACAGTAATCAATCGGTTACTAACTAGTTACTAAATATTTTACTACACTGATCTAACATTTAATTAAATTATTTCATCAAAACTTAATAAGTATCATGTAGATTTGGTTACAACCAAATTCTTTTTTCAGTGCAATCGATACTTTATAGAAAATCTATTTTGCTATGTCAAAAGACACAGTTTCCATTTACAATCGTCGCGTATATGTGTATTTCATGGAAATTCACGCGCGCTATGCATATTACCGAGTTTAGCAAAATATACAAGATGGGAAGACTGCGAACATTTAATTACTGGCAATCAATCTTTGTAGCTATCGCCATCGGTGCTGCTAGTGCCACCCACAAGGTTATCTGTTTCGGACCCGCTACTCTTCCCTTTCCCCTACACAGCTGCAACGATCGATTATTAGACCATTGCATCGAAATACGGTGCCTTGTTTATCCCCCTTAATTACACAGCGCTGATCGATAGAATCGATTTTCGTGAATTTACCCCACAAAATTGTGGACTTACGGAGGGGACCGGCGGACGCCTCTGTGTTATCTGCAACTCTGAGGAATACGGTACACCACTGCACCAGAGTAGATAAGACACCATGACTAAATAAATAATTACATGTTAACGGACTTCTCGTGGTTTCCGTCATCTTAGTGAAAAAAATAGTGACTTATCAATTATCACGATTTTTTCGCGGCGCGGCGCGGCGTTAATAATTTTAGCGAAAATACAGCGAGAAAACGATACTTCAAAATTTATTTGTGGGATATAAATTTAATTCTTTAATCTTTATTTAAATATGGCGAAATAAAATTTGCTAGCAGATATATCAATTAATTAAAAAAAAaCAAGATATATTTCGTAATATATTTCGTAATTACAATCAAATTATTTTTAGATAAATAATAAATAATACAATAAATAAAAAAAaGCAACATTTGTTTACTAATATTTCGATATTTGCTAATTTTTCTCATTGTCAGTGTGAATAAAGCGCAGGAGTAAATTTGTAATAAATACACGTTGCTGTGTGTCATAACGTTCAAAGAAGCACTGTGCATATCATTTTAATATTATATTTTATCATGCAATTCAGATATTCGTTATTATAATTCGCTTAATGAGTTAATTTCAAAGCTTTCGGTAATATCGCTTTGAAACAAATGTCAGTGTCTACGAAGAAAACAACGTGACATCTTCTTTGCCGATTAAGCATTAATTTCCGCCGTTTGTTACAAAGCGTTACGAATCAGCATCGCTCTGTCTGCGTTATCAGTCTCTATTACCATTTTATTACAGTCCGTGAAAATAAAGGAATGAAATTGCATCGCGCCGGCCACGTGTACCTAGTGTTGAGTTGTGTGCAAATTGATGAGCCTGTCAGTGACATTTCGATTGATTCATTAATACCAAATGGAAATAATAAGCTTTACCAAGTAATCTATCATGAAAATACTATTATTGAATGATTCGCCGACAAAGATGTAATACAGTGTAAGTGAATATTTCACGCATTGAATATTCTAATTGTGAAAATCCGCGGCATATTATCATGAGCGCGGCAATACAGATTAATAATTTTCGATACGGAAATACCTATTTCAGTCTATCGACTCGTAAAATAAAATCCAATATCATGCCTGCCAAGTGCAGTGTTATGTCATTTAGACGATTTTCCGGGAATGGAGAAAATGTAAATGCCATTTAAGTGCATCGTATTCGATTTGTATGTCCAAACGAATTAATTACTTTGTCAAAACTTAGCAGAGCTCAATTTCGCTCGATTGAAATCACGAATGTATGCGCAATAAACCGTAAAATAGACGATTCTGTGCAGCCGAAGATGCATCGTGGTTTTCTTATTAAAGAAGGCGACACATCGTGACTCTACGCGCTCAACCTGTCGTTCCACGCGACGTAGAAAATATATTCCGCTAGGATCTCCCCCCTGCGACTGGTTCCCGGGGGAATATGCGATCCCAAGGCACGTCGTATAATGCGCCAGAGTGACGCATCGGCGGAGTCTGCATAACTGCATATATATCCCCATAGCGATTCGCATCATGCAACCGGGGAGCTTCGTTCTTGCTCCTCGTCCATCACCACATCCACCCTCGCTCGCGTCTACTCGTTGCATTGGTAGGGAGGGGTTGGTCGCGCAAAAAGGCGATCAACCCCTGACGAGATAAACGGCGGCCTGTTCAATTGTTAAATTCTTGACCCTACGTGAGGGTGGCGCAGAGTACGTGAAGTCATTTAACGTTGAAAAATGTCTGTAGTTTCTCTTGGGACGAGATATACGTGCCTACTGCGTAATTATTGTTAATTGCGAAAGGGTTGATAATTGTTTCAAAAATAATCTAAATGATAAATGTTGAGAGTATCTTAAAAAAATTTAGCAATGTAGAAATTACTTAATTTATTAGAAATTTTTCGCATGCGTACTTGTCCTCTTACAAAAACTATTACTGTTCGTAATGGTTTTCTTAAAAAAAaTATATTTTAGAACAGTAACAATAGTATGAAAAAAACTGACATCTGTTATATTAAATTGTTGAGTTTAATATTTGTACACAACTCAATATTTTACTAATAATTGCCAAGCGAATTACAAACGCTTTATACAAACGGCATTAACTTCTAGGAACACTTACGTACAATAAGCAGGTGTCATAACGTTTACGCCGCGTCGCGATAATAACTTTACATTGTAAAACTCGCGAGCCAATCCTTTTAATTTGCCTCAGTCACGTCAGTAGTGCGAGGACTTCACTTTTTTACGGCGTTCGTGAATACCGAATAGCGTGTGTTGTTTTCATAATTGCACGAAATACAAATGTTTCCAGGTCGTTGACTCATTTTAGATTTGAATTATGAACGATGACATAATGCCACCTAGCGCCATAACCCAAGATGCACATAGACGCGTTTTTCGTATGTCACGAAATGGCGATTTCGTCCATTTTAGAAAATGGGACGCAAAATTGTATACTGATAATTAAAAAaTTAGATTCCCTTGAAACATTTAGCATCGAACGACGTCGCGATTTTGTAAAGAACTCACAATCGAATAGAAGAACTCCTCCGTAACTCAAATCTCGTTTCTCAGAGTTCCACTCTCGTGAAAAGAGACACTGCTCTGACTTTCGGCTGAGATTAGACGCACTTTTGGTCGTTACTTTTTCGCCAACGCGCAATTTATTCGCTCCCTCCCCCTTCTCTTTTCTCCGGCAGACAGTGGCCATCGCGTAAAAACGTGCACATGTGACGTGCATGTATGTATGCAAGATAGACGTGGAAAAAAAGAACGAATGGCCTGGGTCTGCAGAACCCACGTAATCCTGTGACTGATTGTAGGTAATTACGCCACTCTCGTTGGCTCCATGCCGCCACGCGACGTCATGGTTTAAGGGTGTTATCTCGAGCGGAAATAAAATCTCGAAGACCTTCGACTCCAGCTACCTCGTCATGGTTTCTTGTTTCGAAGTCGTGTTAACATTTTCTCGTTTGTCCGTCTTTCCTCGAGATTTGTGTCTTTTTTCCCTCTTCTGCTCGCTCGTATATTATTATATTTTGCATCCAATACAACTGGCGGGATTTTAAATATAGTTTCAGCGCAGTTGTCATTAATATAGTTCTAAATTTATGTAATATGCTATATAGTTTTAGCTTAAACGAGAAATTGACAAGTAAGAAAATATATGCCAAATAAATCTTAAATCTTTGATGCATTTGATTAATAATGAAATCAATATTTATCAAAATATATCATTCGATCTTGATTAACACGTCCTGATGAAAGTCCTCGATGAGAACGGAAACGTTGATAATTACGTAATCAGACACGAAACTGACACGAAATTGATGACGTATTGACCAACCGTTTTGCGTATCTTTTTAACTTGCATATACTCGGCCGTCGCGAAAAGTCCAAAAAGCGAAATTCAATTCACGTAGACGAAACAAATGACGCCGCGCGATAGCCGCCTGTCATTCGTTGAACCTCGCACAGTATTGAAAAAAAGCGTCCAATCGCGTACGGAAATAACTTCGACTGGCACGTTTCGCGCTTCTGCTATTCTCGCTACCGCCGATCCATCTTGCTGCCTCAATTTTGTCCTAGTCGAGTTCCAAGGCGAAATGACTCGCGCGCTTGCGAGTCATTCTCGTTTCTGCTGGTTTTGACAAACTAATTTGTCGCGAAACAATGACGGCCCCGTCGTGCTTGACGGCGACGATGAGACGAATGGAATGTGTCCAATCATCGGCTCGGGTAGGAACGTGCACATTGTCCGGCTTTCAACTCCGAATACCCTGAAGCATCCAACGATGTTCGGGCCCCTCGTCCCCTTTCGCTCTTTCCGTTGCATCCTGGATCCTCCGTTTGCTTATTCATCCGTCTGTGCGTATCTGTTTATTCGTCCGCGTATTTAATATGCCGTTTGCCCGCACGTGTGTTTATGAATTTACGTTTGATCGCGAGACAGCGCGGAAATTGGCGGGCATAAAATCTTCATTTAACTTGGGGATATTTCGCTCTGATCGAGCATAACACGGGAATACATTCCACGGCACTGATGCGATTTATAATAATGTTCGCTCATTTAAATTGCATCTGGTTTGAATTCCAACTGAGGTCAATTAACAATATTGCGGTAGTTAAGAAATGAGCAATATGAATAAAATTATACGCGAATTTAATTATATTTTTCCGAAAAACGCCATATATTTATGTATATGCGAGATTTAAATATGCTTAATACAAACGTAACTTTTAAAATTTTATTATTAAATATTTTCCAGTTTTTAATTATTTAAAATTCTTTAATTAAAATTATTGTTCTATTCGAAAATTATTTGGTTGGTAATGCAGTAATTAATAAATGTGCACCGTAATAAATGATTCTGCATTTTATTAATTTTTTCGTATCTACACACACACATACACGCGCGCGCGCACGCGCCCGCACGCATACACACTCACATTTTTCAGGATAGGAATAACAAAAGACGTTCAATAATACGTTGAACACGCGTAGAACACGATGAACAAATTTCGCGATTTAGGAGCACATATATTACGCTGGTCTGAGACGGGCACGAACGTTTCACCAAAATTCGCTCTAATTTATGGTGGAGTCAATCATGTTTTTGTCTCGGTGTATTTATCGCAGCTGTCTATCTCTAATCTGTGCACACGCTATCGCGTTATGCATCGCTGGACAGAGTGTCATTCCGTGTTTGTCAGATTGCACAGTGCCCGTCGTCGGTGGTGGGGAACAAGGGTAAAGCCCGATGAGGTATGGCAGCATAATCTAATTAAACCGCCGATGGACATAGTCCCCGCGTCTAACCCCATTCCCAACGCACGTCCGTACATATCGGCTGCAATTGTCTGATTTGCATGTAAAGCGCACACGTCTCGAAAGCGCCGCGATTATTAACACGGAGACACGCGTCCGCGTCGCGCGTCTCTCGTATACGCTTTGCTCATGTGCATAGGCACACGTCATCGGTACACAGCATCCGCAGACACATCCGGTGACAGTCTCGCATGGTGCCATTTCACTTTCCATTATGACCAATCAAATTCGGAACATTGCACGATATTCGTTAGTTACGTCAAATAAAAGATAGATACACAAGACGATATCAATACACGGTCTTCTCTGTACAGAGTTATTTTCAGAAAATGTGGAAGTTAATTATGGAAACTAATTTAGAAGGTAATTTCTATAGTAACGTGCTGCATTTTCAGAAAATATGGAAACTAATTTCTCTATCAACGCGCTTCATTTCTATTATATTATATATACATTGTTAAAAATACACAGCAAAATTTAATGTAATGTAGTGAAAGCAAATTTCGAGCAGATGCATTAAAAAAATTATCTCCTAGGCCTCTTCCGCCTCTGAGAGAAGGAGGAGGCCAAGGAGAAATATCGGGCTTTAGCGGAGCAACCATGGGGTAATTACAATTCCTTACATAAATTTAATAATCTTTTTCCTCTTTATTCCATCTTAATCGCAATAAATTTAAAAAAAAGATATAGGAAATTCGTATAAAATTTTATACACACCCAAAGAAAAGTTACGTTATTAGCCTTTTTAAAAATAAATAAATTATTTGTTTAATTTAATTATTTAATTCAAAGAAAATATTGATAGAAATGTAAACAAAATTTAGTTCTGGTTTTAAAAGTATATTTCTTTCAATTAAAAAAAATTTGCGTTGTACAACCAAACTGTTTTTTTtAATTCTAATAAAATCGAAAAAATTTCTTTGAGTTAAAGAAATTTTTCTTTAATCATATAGCCATGCACAAATTTTGAGTCAAACAAACATTTTTTTACTCAAAGAAACCTTTCTCTGGGTGTATAGGAATTAGTTTTTAAAATATTGATTATTTCAAGCGTAGTTTTAATTTTTtAATTTTGTGTTTGTGTGTTACAGTAACCACCGCTGATTAACTCCACTCGTTGCACATCGGGTCGGTAAGTAAGAAATGAATTTTCTTATTATTATTTCAATGATGTACAAAGAAATAGTTTCGATAATAATTTTGATAAAATTTGGATAAATTCGACACTCTGTTTTAAAGCCAAAGCATTTTAGTCATCGAATCGACCAGATGTATGGGAAACAAAATTAGGACGGTTTACCGACCTCATCTTTTATTGAGAAGAAATCTGTTTTTATTCATACATATACAATTGGCTCGCTTAAACGTATACCGATTTTACATTCTCGAGAGCTCAGCTTAAGGATGCTCCATGCAGACGAGGGTTCTTTATTTTCCTACGGCGGTAGTACCTCTCCCTTAAATCTCTCGTTCGGTGTTTTCGCAAGCGTGGACGCCGTTCGCCCTCGACTACTCATCCCTCTCCTTCGATTCCTAGTCACATCCGCTCCGTCGCGCTGGCTTCTTCCGCAGCGAACCTGCACGTTTTACGACAAAATACGATTTGCATAGCGGGGGAGATTCTTGGTACTGCCGGTCGAAGATGAAAGGGAAATATTCTGAACGAAAGAAAAAaGAAGGCGGAAAGACGGCAGGGGGGCGGCAGAAATTGAAGACACTACACTCAATCGTGAAGCCGACGCGACAGCGTCGCCAAGCGCGTGCAGTTCAACTCAAGTGTGTAGGTAGGCACTCGGGTTCGCGACATTGGGGTTGAAAGGCGCGCTCCAAGTAATTCAGGTTTCTACAGTTCTGCACGAGGGAACACACGTCTTCACGTCAACGCATGTATAAGCGAGGGGAGGGAAAGATTGACATTGGCTTCCGATATGCCATGCTGGTCGCATGTGTACGACGCATCACAATAACGTCGCGCTGGGGTCTATTCGTCGGATTCCGCTCACTGTATCCGACGAAGTTGAATAGCTTCTGTATCTGTCATTCCAATCCCGCGAGGCGCATAAGTATCCCGAGTAAAGAAGATTGATCGATTTTTTCTCGCAACGATATTTTTATTGTACGCGTACTTTGTAAAACTGAACGCTTTTTTATTACCCTCTCAAGAAAAGAGAAGATGCAGAATTTCTTAACTAAGGAACACACAAAGCAAGGGCGCCCATTAAAATCGTTAACGACGTGGTATCGTTTAATCATTAAAAACTTTTAAAAaGTAATTGAAATACGATTGAAAATATTTTCCTTCCCTCGAATGGTTTTCCTAAGTACTACTAATCGAGTAACGTTGCAATTGACGAGTATAATTATTATTTCAATGGCGTTACAAGTACTTATTGTTTCTGTGTAAATCGCCGTTGAAAGTTCCAATCTCGGCTGGTGGCGGTTGCAATTTACACGCAGCATTGTGCACGATTAAATTGCATCTACACCACGCATGAAGTCGTTCCGCGTACGTGTGTGCGCGCGTGTAGGTGAAACGCGGGAGGAAACACGGTGCATTGGCACATACAAATCGCATAATAATTTGATCGATCCAGCGCAATCCAGCCGCAGTGGGCTCCTTAATTCGTCGATGCTCGGATTACGGTTAGCCGGAAAATGCTTTTGCGGGGGTGGAAGTGATTTATTCGTCGCGAGCGGTTTGTCGAACGGCTCGTCGGGCGGAAGTGCCGCGGAATTTATGAGCGGGGGgAGGACTTCCGACTAGATTTTATCGTTTATCAATAACGTCCGAATAAAAGTAATGCGGCCGCGCATAACCGCGGGGAGAAGGAAATCCCGGCGGCCGTAGGCTTGGCCCGACGACAAATGGATATTCCGTAGACCGTATTATGAAGTCGGCCGCAGATTCGATGTAGTCCATTTCTCCGGATCTTCGCCCTCGCCGCGTGCAGAGATAGAGCTCTTTCGGTCCGCTTCCGTACTGGCAGACGATTTAACGGTCTGCGTCAGACGTTTTTCTTCGAGAAATAATGCAGACGACGTTTCTGGTAAAAAATTAATAAGGTGTACCCCTATAAGAGGAACAAGTGTCGTTGTGATTTATTTTTtGAGCTCTATATAGGTTTCATAAAAGGTATATGAATATCTTTTTCTCAAAGTTTTTCATAATCTTTCAAACATTAGGTACAATGTTCCGTTTAAGTAAATATTTAATTATATGGACGAAAATGAATACAGTGCATTTTGGCTATACAATAAGAAGAAAAAATTATAAAGATTTTATTACATAAAATGCAACCTGTTTCGAAACTAGTGAAATAATTTATAATTGTAATAATTGTTTAATTTGTCAACGTGGGTTGTAACTTAATAATTGAATAATTATGCATTGATCATATTGAAATAATATTAAAACAATATTACTAGATGCTATATATACAATAACATTAATAAACGTTTTTAAAATGTGCAAAGTCACATAGCACAATAGAGATTGCAAATTAAATTTTTATAACCATCTTTTAATATTGTAGGACAGATAGACTGTTATTCTCAACGAATAAAAAGTAATCCTTATTTGTTACGACCAATAAATGTGATCACGATTTATTCGTGGTAGAAACATCAATTATTATATTAACGGAATAAAGCTCGTAAAATCGTTCGTGTTCTCGTTTGTCGCATTTTTAAATTGTGAAATGTATGAAATTTGCATTATTCGTAATTAAATTGATATTTTTCCCTACTAATATTCAATATCGGATGGAGATGATTCCATTAAGGGCGATGTCGTTGGAAGCGGGGCCGATTATCGGACCGGTCGATCAGCTTGTTATAGATTTGCCAGCGCTCTGTCCAGAGAGCAAAGCTTTATGATCCGTATAATGCGGTACAATAGGAATTAATGTCCCCGCGTGGCCCGATAAAATCTCGCGTACCGCGCACATAAGTATTTTATGTATATTCATTCGGCTTGCACGTTGTGTCGTCGCGCCACGCCGGGCGAAATCAAGACGTGATTTATGAATGCCCGAGTCGCCCGCCGCGCCGTCGGTCTGGATGCAGCGCGACTGCGGCAAAGTCGCAGAAATCGTTGTAAAAAATTTAACTGTTTCGCCCGCTGTACGTTTCTGCTTTACGATGACGACCTCTTCTACGCGCCGAGAATTATTACAGGCCTCAATCTGATTCCGCGAAAGGTATATATCTGAATAATGCGACGAGGCTTAGCGATTCGATCAGCCCAGTTTTGAGCGCATTACGTTCCACGCATGTAAATACTTCGCGTTCAATTTCGCACAGTAGGCAAATTAATAGATGATCAGCCGATTGTTTGGACAGGTAGGTACGCGTCCGATCGAAATAGCGCGCGATCGCCACGCGAAATTTAGCCGAGCGTTCGCATTCGATTGTTGTGCCTTGAATGCTACGAGTTAATTAACTATTGTAATTCCACCCCCcTcGCCCCCCCCCcGTAAaCAGTGTTGTCGAACATTCGTGATTCATTATACGCGCGAGGTGAATTCGTATCCGATCCCTTTCACAATTCATATTCGCCAACAATGTTGTGATCGAATTAGCCTCGTAGGTCTCCACAATTTTGTGTAACCATAAAATACTTGCATTAAAACTTGAAATTGAATTTTATGAGAAAACTGCAAGCTCGCAATTTTCGCAATTACGTAGTTGAAGAAAGGAATTGATTGCGCCGATCGATATATATATATATATATATATATATATtatttATTTTTTTTTATTTTGTCNNNNNNNNNNNNNNNNNNNNttcgaaacgtcgcgcgtgtgaagTATCTtGAATAtCATTGTtCTTTttCctACATCCgACGATCACGgTGCGCTCTCAAgACTATCgACTTTTAtATCCCATACGATAGATGCTTGACGCAAGAGGACCCGTAAATCGTCGACGAGGCGACACTGCCGATGTTATCAGTGCGAATCGGTCGTCCAAGAAACGAGATACCTCATTCTTCTGGGAAAACGATAAATTGTGATAACCACAATATACCATATATATATATATATATATaTtTtTTTTTTTTTTtATTtGCAATGACATTTTTGCACAGTTGTCTATTATGCGATACGAACGATTGGTTTAGCAACGAGAAACAAACCTCTTTGATGCGAAATCGTAGTAGCGATATTTATCCCACATTGAAGGAGCTTGATGACGAATGGCGTACTTACCTGAAACAAAAAAGAAAGGAAAGTTAGCGCACGAGAAATAAAGTCTTATATAGAGTGCATATTCGTCAGCTCATATAACGCCGCAGAGAAATTAATAGCTCTGATTCGAAGAAAAAAAGTTCTCCTGAATCTGAGCTGGGCGTAATTACTACGAATAAATCATTTCGTGAATGACACTGGTTTTTCGCTCATCTAATGTCTCGGAAGAAACCTAGTAGCCGGTTAGGGGAACGCGCGTTCATCCACGTCTGCGTCGCGTCATTTATGCGAAACGCGTGCAATTTGTCCTTATTATGTTACACGCTTGTATTGGAAGGTATCATTCGTCGCTCCTCTACGTGGCACACACGTACACTGCACACACATGTGCGTAACCGACTGGCCGCGAAAGAGGGCAAGAGGAAGAGGTACCCTATGCACGAGACTATACGTCGGAAATCGTTGAATTATTTAACACGGGGGACATCGATCATCGCGGTCACGCGATACCTACGTCGGCACGGCGCGGCGGCTTAGCCGGAGCCCTACGTAAAGTTTAATCCAGTGACTTGACCCCGTGTCAAATCGCCGTCCTCGATTATCGCGGGATCCGCTCGGCGTTCCGGATATCGGGGAATTTACATTAAAGAATATTCAAAGCCGTCAACATAATCTAGAGACTTATCGGTACCGCGCCGCGCCGCGCCGCACAAACGTCCGCACCACGTATGTACGCGCATACGTGTATGTCGCTATATCGTTGAGAACACTTGGGAAACTTGTTGCCCGTAAACTGGAACGCTAGCTTAAAGCCGTCACTTCCTATAAGTTTCAGCTGCAAACATGTAAAGCCCGGGGACGACAGGTAAATGCGTTATCGCGTAATTATTTTAACGCTAGGTTGGTCATCTTTACCTTTCTGATTAATTTCACGGAAGAGCGGATAGATACGAAATTACAGGTTGCTCCAGCGATATAATACTTAAATGATATACATTCTGAAACACGTCGTGCCGCTACCGGCGTGCAGCCGCGGTTTCTGCTTTTCATAAATTATTACGAAATTATCCCTCATGTTGTCAGCGTCGATTACGGTACATGTACGGTGTGTACGTGAGGCCGCAATATTGGAGTTTACGTGTATGTGCGTGTGGGGACGATTGGAAAAATATTATTGCGCGGATAAATCACGGTCGAACGAGTGGTGGCGCGCGTATGTACTTAGGACTTAGCGGGCTTGATTACACCTTGTCGAGATGGGCACGGGTCAGCTTTCGAGAGTTTTACAACGGCGATACGTGTGAGAATTTCTGGTCAACGCGCCACGGTTATTTGCGTTCGATACCGGCAGAACGTGTGGAAAGCCGTTTTAATAGACGCAGGCACTCCGATCGGCATGGCGTAAATCTCACGCGTTACGCACCGCCATCGACATCCTCGTGCTTTTATTGCATGTTCCCCCGTGCCCACGTTGCTCTCGCTAAAAGAATTTAATTAAAAATAGCCAATTCGCGCTCTTTGAATCTCTGGTAATAAATACAGATAACAGTCGGTACATAAATAAATATTATCTAACAATATTTAACTACACTTTGGCTAAATTATTTCTGAGGTTATATCGCACTGAGAAAAATGGAAAAATACTTTTTATCGTATAAAAAATACTTGTGTATTGAAAAACTAATTGTTATAATAGAATCGTGTTTCACAATGGCATAAATATTTTGTAAAATATAGAAACAAAATAACATGTTACAGAATTGATGCCGTTCTTGAAAACATTAAAACTAAACGTAATATCTATTGTAAGAAGTAAGAAAAGTTATTCAATTAATCAATTATATTCTTAGAATGTGTGTAAACTTGGAAATTCTGAATATGCACGAATTTATAGCGTAAAAGTAAGCTCAATGTATATACAAAATTATATTTTATTGTATAAAAAATAAAATTATAAAAATTACAATTAGGAATTCATATATAAAATTAAGATACGTCTTGAAAATAGAAATAATTTTTAAGTTGTGTGTGAGCTCGAGGATGATGTTCGGGACAGATCATACAGCACTTAGCGCGGGATAAAAAAATTAACGCTCCATTATACATGGTCTCGCTGATACGATCTGTAAAGGCTTAATTACGCCTTCCATCTCGCGTCAATGGGACTCAACGTCGCCGTAAGAACCAGTCCTCTAACGAACGCGCGTATCTCTCTCGCCGGGCGAGAGACGCACAATACTTCTCCCCGCCTACGATAAATCCGAGATAACGTATATCTCAAACGTTCAATTATCAATTACCCGACGTATCCCGCCGTGCCGGTGGGGCATTTAGATATGGCTCGTTACGCCACATGACGGAAACACCGGGAGCAACGTGCTCGTGCCGTACAACAAGCAATTTTCATGCCGACGAAACGCGGTAGCCGCGCGATTGCTCGTTACGCTCGTGTATCCGCTAGGCTACGTGCGCGTGTGTCTGCATGCCTGCCTGGACCGTCGAGCTCGAAAGAGTGACTCTCCTCGAGGCCAATCGACCGGCTAGAAAGTAAGATTACACGGTTTCTCGCCGCACACACGCAAACCCATTCGCGCACCATTGTGCCAGACGGCGCGTCGTGCTGTGGCCTCCTCTGCTCTCCTCTCTTCTTCTCTCTCGTCTCTCCGTTTTTTTGTTAAAGCGAAAGCTGTGGCGCGTTGCACCAAGCCCGCTCTTTTATTCTGTGCCTTACGTTAACCGCATGTTCCGCTACACCTCGGTGCTTTACGCTCGCCGCAACATCAATGATGGATTGATTCTGGTATCTTTTTGAAGTCCGATCTTCTGAAAATCTATGGGAGAATGTTTCTGCCTTATCTGTCGCGGAAAGATTAACACGGAAACATTTCAGGCGGTGAACTACCGTGATATATAACATTTGATGAATTGATGACGAGATCCAAAAGCTACGTAGAAACGCAGTCGCGATTGAAGTGTAACAAACTTTGCAAATGATGTGTAATAACGTGTGTATTTTTTTCTTTAAGACCATTTTCATTATATAATACTGGTTAAAAGTTAAAAATTGCTTCTTAGGTTTATTCTTTTTCTTTTTTAATTAATGACAAAACATTTTAAACATAACTTCCCCAATTTTCGTCCTGAAACCAGTAAAGAATAAaaAAAAAAAAAAaTGGCTTAAATGACTTACGCAGCAAAAATGACTACATTTTGTTGCAGTTTTTAGTAAATAACTTTTAAACAAGTAAGTGGATTTAAATGAAATTTTACTAATAAAATATTTATTAAAGTTTTATTAATATTATTAAAAAATTTGTAATACGATTTTCTCATCAAATTTACAGACCGGTGTTATTTTCGTGATTTTACATAAGAATCCAGAGTGGACAAAAAATTAAATAACTTTTAAATCAATAAGAGAATTGCGCTCAAATTTTTATAAATATTCAAACGTAATAATATAATAGATTATGAAATTTTTATATTTTTAATAATGTTTTGAGTTGTGACACATATATTTTTAAACTACATATGTAGGTACATATGTAGCTTGTAAAAGAATTTTACAAGATATTTTCCTCTCACTGTTATCAACCAATTTGAGCCTTTTTCTCGGTTTTACTCGATATCACGCATTTCAGATTTACGCAGTACATATATATATATATAAAGACGCCAATTTCCGTATTTCTACCGTGCAACCGCGCACTTCGTATTCGACCAATGTGCGACACACTCTGGTCCAGCACTCCATTTGCATTCTAGACAAATCCAATTTCCTAGGAaCAAAGCTGACGTGCCAAAGAGGGCAGTCGCTGGTCGATTTTCTCTCTCTCGTAGGAGCGTTGTTGGTAATTGTTCGAGTCACGCAGCCCAGGTGATTATTGGAGTAAGTATATTGGAGTTCTGCGGGAAAAATTACATAGAAGTACGAGCGATAGGAAGTCCGTGCTGCTACATGCGGTGATCAAAGGCAGAAGTTGTTAAACGGTCGCGCGAATCTTTTGACGACCGAGGCATAATAAATCTACGTTAACGCATTCCTCATCCACGATCCGCTTGCGCGATTATTAATGCAACGTTACTTTAATCTACTTATTGCCCGTTACATCATTTTTCACTGGCCAACTTCCCAAATTTGTCTCTCGCTGCAATGCAATATGTTTTGTATTTCGTAAGAGATTCAAAGCACCGTGCAATTTACTTCACACCTCGATAAATCTGGCTGCAAGCGTTCAATCGTTATTAATTAATTTCGGTTAATTAATTTTGAACACAGCTTCTATGTAAAGTGTAACGGCATTCTACATTATTATTTCTAAATGTTCCGTATTCATGAATATTATATCTAATTATTTGTTGTTTTGAGTTGCTGTTGAGTTATTATTTATTGAAAATTATCTGTAGATGAAAAACTTTGACTAACTTGACAATTTTTAGATACTACAAGCTATTTTTAGTTAATCATGTTGCAAATACAACAATATTATATCTAGTGTGACAGGTGAACTTTAGTCTTTTCGTACATTGTACGAAAAGTATCATTAACTAAATTGATTCAATGTCTATGCGATCTTGCGCTTTCTGAGACAGCGCGACATTAATACTGTAAAATGAAAGTGTCGATTGTCAATAGGCAAGTGTGAACAAATGAGCGAATGTTTGTTTACAAATGAGGTTGTAAATTGCTTTAACCTACCACTCGGTTGCACGGGAAACGGCCTGCTGATGTTTGCAGATAACTGTACGGTTGTTTCACCACGTTGCTCGAAAACATTACGGCGTGTTCATCGATTTTCGCACGAACGGATGTTAATGTTACGTTCGAGCCGCATTTGTAACGAGCGCGTGCGAGAATCGTATGTCCTTCAGGCACACGTGTTCAGTTACGAAGTTCTATCAATGAATACCTTAGGACATTCAATATTATATCAAATTTGACCAGAAAATAACAGTATTAATCATTGTAAATTATTTCAGATAGAAGAAAATCTTAATACGATACATAAGTGAAGCGAGATCAATTTATTATTGAGAAAATTTCTATCTACATCCATCAAGATGAATAATTGAATTTTTTTATTTAGCAAATCGAACTATAAAAACTATGTCATTGTTTGCAAAAATTTTATTTATTTTATTACACCAAAAAaCCGGATTTTTTTtATATTTTTAACATTGCTAGCTGACATGTTGTCACAATATGATATATGACTCTACGTTTCAATCGATAATATCAAACACAATAAATTTTACTGTAGTATAATGTAGAAAATATAGTATATTTTCTAGCGCGCAAACAAAAATAATGAAAACGCAATCGGTATAGATAAACAGTTACGAGTAAATATATAATCGTAATTAAAATTGTGAATAAATGTATACGATATTGATGTTCCATGAATTTTATTCAGTATGTAATTTATTAACGTGTGTGCCCACCCACGGTGATACATCTCTCTTTAAAAATAATATGTTTCCTACGGAGCCCATTGCAAGCAATTACAAGAAAGTCAGAAGAAGATTTGCATATAAAGTGCTACTATTCGCAAAATGCTCGGTTAATGCATTATTATTTAGGACTTTTTAAGAAATGTAATCGTTATATGTCCCGCAAGTTCGCCTGCAGACCGCATATTAATGGAATGATAAAATTAATAGCGTCGTTTCTAGCTAATAGTTGAAAATAATAACGGCGAAGCCATGTCTCGACTTGGAAACTCTTACATGCTGTTATCACAAACTTTCTCTCACCCCGTTGCTATCCTCTCCGGGTTATATTTCTTCGGTGTCGACGGACACGCGATGAGCCTCTCCCACACGAGAAACTCGGAAAACAAAGTTCTTTGACTTACGAAATTTAAAGAGGAAGAACTCTATCCTGCTCGACTTTTGTCTCCGTCTCGCGCTCGTTGCGGCAATTTCGGTCTCTTTAAGAGAGTACGTTTAAATTGATTTATATTTGTATTAGTACGCTAACGGTGTTTGACGAAGAAAATTATTTATACGTAATTACATAAGTTTCTTAAGACCATGGCAATAAAATTTCATAAAAATTATAACTAATAAAATAACAATATCTTATTATAAACGAATATTACGTATTAAATTCACAAAATAAATCGGAAATCGAGAAACCTAACCCTAATATAGTTTCGTAGCAATTAAATTTTATGCGTTTATAGAAATAGCAAATGGTTTAATCAAGTGTCTTGCAAGACTTATGTGTTTCCAGAAAACTTAATAAATTTTCAATTTCCCGAGGCAACTGCCAAGAAGATGATACCATCCCAGGAAATAAAATTAAATTTTTAATATAAACGAGGTTAACGTCATAAAATGTTAAAATCTTCTTGAAACGAAGAACAGATTAAATATTGCATCAGTTCTTCTCTCCAACACTTCTTTCCACGGCTCAAATACATGTATATGAGAGACGGAAATCTAAGCAAACTCTTAAGCTATTAAGGTCAGCTGTAGAAATTATAATCGTCATAAAACGCAGGTTGACGTTCCGGTCGATTTTTCTAATCCATTTACTCGGGGCATAATCCGCTACCACATAATGTCGGGGGAGCTGCGAGAAAGTGCCTACGATCTTAGGATCGTCAATGGAGTTTCGGTCCAGAAAATAGGAGGGTTGAAACGATCCGGCGCGTCGTGCGGCATGCTCCTCTCTTCGCCGGCTTAAACGCGTCGTAAGTACTTGAATCGTAAAACGAGAAATATCTCGAAGGAGCAGTTCGATCCCAGAGCTTCCACGGGTCTAAGTAAATGCGCGATGAATAAGTTAGGACGAAACGTTCCGCAACACCATCGTCGCGAGGAAAGAGTATAGTATCTCTCTGGTACCTTCGGGTGTCCCTCGGGTACTAGATAATCGAATAGTATCTGATGTACGTGGCACAATAACCGTCGATAGGGCCACAAGACGGGCCGAGGGAACGGCCGCGGTCGTTTGAGGGTGTATTGGGGAGTGGATGAAAAGCTGCCAAAATGTACAGCCAGGAAAGGTAGAGGGAAAGATTCCGAAGACGAGTCGACGGATTGACGGACTCGTAAGATTAACTCCGCTCAAATTCGATAAGCGTTACGTATTTGATTGCACGTGAACGTGACAATATGCAATATTTGCACGGTGAAGAATCACTATTAACGAGATATTTCTATGCGTGTAAAGCATACGTGCGTAAAAACTATGCATACCGATGAAATTTATTCGAAAAAGTACGCGCGAAGCAGCGCGCGGAACAGTTTGTGCAAACATATGCGCAAATTACGTGTGGACGAAAAATTTCTACATGTGAAAACCACCAAATAGTTTTGCACTATGTGGAAAGGGGAATTTCTGAAAAATGGACGGACGGATGGTTTCGAGGATGAATTTACGCGGGTTGCGTACAAAAGAGTAACGGCTCTAAAGTCTGCCTGTATTGAAGATTGTGTTTCGCAATGCGGCGTTAGGAAAGAGTTTACTTGGGTCGAAACCTTCATATTGTATACATCTCTGCGATATATGCGTCGTCTAATGCATCGGCGACAGAGAGTGCTACCTACGATACAATAGCCTGTCGTAATCGCGAGAAGGACCAACAATAAGCATTAAATCATTAAGCCTGCCGGACACGTAGCCGACAATAGAAATTCCGCGTCGCGCGGACATCATCGCAGCTATTACGACCGCGCGCTGGGTTATGTACGATCTCGCCCGTTCCACCCTTTGTCTCGGCGCGAGCGAGCTCTCCGCCGTCAACCCCTGCGGTATCGGCTCCTCTTCGGAGCCGCTGTTTCCTCGTCATTAACTTAGCCGTGCGTGACGCCACCCACGCGTCGATGCGTCTACTCGCGCGCCAGTAGGCTCCCACGCGCGTTTCGCTTTTCCTCAGCTTCTCGCCGACGATCGGACGATGGCAGCCGAAGCTCCGTACCGAACGAGTGTCTGACTGATGAAACCCCGGTCAAATTAAATCCGTAGCGATTCACGATCGTGCCGCCGGCAGTCGCCTTCTCCGAAGTGTAGCCCGACCGCCCTGCCGCCCACCCTTGCATCTCATTCATTTGCATTCGATTCGATGCGCGCTTTCCAAGATATATACGTCGTCACCTTTAGTAATCGTGCGTTTCCTCTCCGACTAAATTTTTGCTTGTGTTCGCAGAGAGCTACGAATGCGGTAATTTACATTCGTTAAGGAGGGGAGGCGGGGTTATGATCTCTTTCGAGTGCGAACGTATCGGGTATCGAGTGACGTCGCTGTCAGATATACGGCGTGTCGTGCGCGTTAAGGCGGAGAGAAGAAAGAGATGGTTGACGAGGGAGGTAGTCTTGGAAACGAGCCAAGATGTAATAAAACGAGGAAAGAGAGGACGGAGGACGCGGGGAGGGAAGCCGCTCGATCATCGCGGAAACTGGAAATATTTTGACGGGCGGTCGGACGTAGCGGCTAAATAAAATTCCCTGGATAATTGTCTCCCGTTCGGCGAGGACCGGGGGCCATTAATTCGTTGGCGTGACTCCAGTGTCTCAACGTCTCCCTGCTTGGTCCCTACCAGGTCCATTCCGCGTGTCTTCCTCCTGTCGAGGGCCAACCTCCTTCCCTCCCGCCTTTTTATCGCAGCTCTTCTTTTTGCGCTCCTTTATACGCGCGCCTTCTTAAGACGCCGTGGTTCGACTTACGACCGAGAGCCCACGGTATTTATACAACTCGCCCACACATCGGCGTACACTCTCATCCCCCGGTTCGTCCGTCTTCTTGTTCGTGAGAGAGCGGATGAGACCTGTGTTCCATTCCTATGTATCAAACTTCACTGCCGCAATTACGTACGATCATCGTGATAAAAGAGTAGTTTCAAGAATTTTCACATTTAATTAAAGCGTAGTATCAAACGTGTTTATTGTTTCGAACGACTTCATTACCGTTCTCAACGTTTTCAAAATTATGGACAATATCCTTTTCTGATTAATTATTATTTTTTTTATATTAAAACAATACAAAACATAGAAAAAATATCTGATATCAACGATCTCTCTATAAATTGCTATAGAAAAATACAAGGAATAAGAGAAAGTGCCACATTTCTTGGTCGAAGTGGATCTTTGTGTTTAATATTTTCATATCAATTATTAAATATATTTTTCTGTTCTATAGACTGTGTATCGATTTGGTTTGTCGGACTTGAAACGGAGTTGTTAACTAAAACTAAAAATAATATTTCAAATTAATTTCATCAAATTGTAATAACAATGTTATAAAATCTTTTTTAAAAAAACTGTAACTTGTTTCTTGTATTATTTGCATATCAATCTAACATTTAATTTATTCTTGTTATAAAAAAaTTTAACATAAAAGGTTAACGCAGTATTTTTTGATGTGTAAGCAACTGGCAAATCGAAACTTTGCCGCACGTTATAAATACTGATTTAACAATAATAGAAACATGTGTTCATGCAAGTAGGCTATTTCGTTTGTGTCTCGTTCCATTGGCGCGCGTGTACATTCCACGATAGTGGAAAGAATAAATTTTAAAGGCTGGTAGAAAGCATACTGACGTGACAATGGTGATATGTTGCGTCGGGTTACTCGGGAAATTCAGAAGCTACTCGACTTTTATTAGACGCAGTACGCCACTACCCCATGAATTGTCGTCCGTGCAAGTGCATCGTATGTTCTACATAGCTTGGTATTACTCGGGAATATATCGCTCGCACGTAATTAAAATGTCAGACGCTGGTAGCACAAATCAATCACTTTCTGCTGACAAAATAAAGAAAAAAGGGAGAAAACTTTCAGTAACGACGCAAGGGCAATAGACAAATAATAGATCCTGTTTGAGTAGTTTGGCCATAGCGATTTATCTAATGATACGCACAAGCTATGCTGCATTACGCCGAAATTTAATGTGTATTGTTCATGCGGACTCTCGTTGGCCGGATAATTCATATTACATTATTGCACCGAATTAATAATGCCCGATATGCGCGCGCGCTAGCTGAATATTATCAATGCAAGGAAATGATGTTAATAAAATATGAAAATTGAATTAACGTTAATAGGGATTTATTAGCTGTGATCATGTATGTAACGTATTAACGCAAGAAATGCATACCTTGATTATTGCCTATAGAATTTGCATTATCTGGATAAACATGTCACATGCAAAATTTCAATATCTGCCACGTCGTTAAAGATGCGGAACAAAAACGAACCGTGGTATGCAAGAAGCATATTATAGCAAGCTGTAAAATATGTCATACTTCTACAATAAAGAAATTTTGAATTTATTATAAAAAGGAATGCATATTACATTTTATGATTTTCTTCAGTTATAAATGCATATTAAATCTAATAATTTAATACAATTTCAACTTTTAAAAATATTATTTATAATAGTATACTTTtAATAATTTTAATTATAAGAAATTTtATTAATTtCGTAATGTTATGTCGAGTATAGAATATTACGCGGTAATGATAGCTGCgTAATAATTATGTCTCAAGATTTTAATTAATGGAAGAAAGCACTCAGTACCTTTCTGACGATGGTAAAACGTTGAATTTGGGTGTGATATCACCTTAATGACCGTAGCGAGATAAATCATAATAAATATCGCTGGAACCGCGCCATGGCGgTTGATTAAAATTTATGCATTTGTTAGAATTATATCTCTCGCGCGGCAAATAAAGTTGGAATGCACGCGTATCCAATTATAACCGGCGGAATTCTCGTTTCCTTTTCGGCGCGCCGACCTAGAAGTATCTTCACACATTGCTGGCGAGCTTTTAATTTCACGCGAAGTTAACACATGCGGATTTAACTGACGTTTACTGTTAACAAAACTATGCAACTCGTAAATTGCGCATTGTTTGTATACGGTATACGTGCAACAATTTTATAAAAATATTCATAAAAATATGCAAAACGAGTCTGTAGGTTTCTACAATTCAAACTCGGGAGATACTACAGATACATATTACATTTACTCGCAATTCAGTTTAAACGTTAAAGCGATGTCTATTGTGTTTTTGATTTTATAACGTTCGCTCTACGCTTGACGACTCCGCAGAGAAATTTCATATTTACGTTTTAGATTCATTCGTAATCATTCCTCGTCCATGACGAGCCATTTGCCTCGAAATGGGAGGGCTAAGTTTTCGTGAATTAGCAAGCAACCGCGAGAACGAATCAAGGAGAGAGCCAGCGCGGACAGGGGTGTTCGAGAAGTTTTTCGCCGCACCAGCGTTGTTGTTCGGAAATGCGAGAGGGAACTTAATTGCATTAATTATCGCGGCGGGTGCATATTTACTCCGCCGCCTCGTTACGCGAACATCGTCAGCCCTTGTCCGCCTGTTTGCGCTCTCGGGGACCTCTTTTACGGCCCACTAAATCTCAAATCAGCCACTTTGTTTTCGCACCACTCGTGCTAAATCTTTCGCTCTGTCTGCCGCGCATTACGCACATTACTGCGAGAGCTCCGCGGGCAAAGCATTCTTATCATAAATGCTTTATTACTTCTCGTGAGTATTACGCTTTCTTGCGCGAGCTTTTGTAAAAGCTTGCGCTGATTTCCTCGGGCTTTTTGACGTTCTCGAGATTCTTTGCACGCGGCGGAGATGTGCGATGCACAAATAATTCATAACATTTTGTACTCGGATACGTATAAGTTTCTGGCATGCGAGACACGCGTCTACATTCCGTCTTCAATGAAAATTTATTGTTCTCTGTGTCGTGGAAAAAGATTTTAAAAGAGATATAATCACAATTCGGTCGAATAATCTCATTTCGATAATGAGCGCGATCAATTCAATTCATTATAATGCATCTCGCGTTTTTCTTCGCGAGCGAAAGCAGAAGCAGCGGAACGCAGGGACGGAATTTAAACAGCGTATCAAAGCGTGTGTATGTCCGCAAAACGTGATGTCACAATAATTTTCTCGCAAAAGCGAAACGCGCACGCGGCGGAGCGCCAAATGCAAATTTTCTGAATGCAGTTTCATCTCGGACCTGGCACTGGGTGAAAATGATATTCTGAAAGTGAAAGAGGAAGGCGTAAATACTTTACTGGATTGCGACGCGCTGGTGAATTACATTGAAGACTTGTTCGCGAATGACGGCATTTATCCGGTTGTAAGCCATTGAGACGCGCGGGCGCGGAATAACCGGGCGAGTAAACGCGAGTGCACCTTATGAAAATCCGCCCGCCTGAAGAAATGTATACGTAAGAGCATGGAGCGTGTACATACCGCGCACTGTGTGTATAGAGGATACATATCAAATTTCACGATCCGGTTGACTTGACGCCATTTATCGGATACGCACGGTCGCGGCGCAACTCCAACCTGGCCGAGTCGTCAGCTTGCCAGTTATGAAATGCGTATTAATTTATGGCTAATGGGTTTTTTAAATCGAAATACTGATCGTGCAAGCACACTTGCCTACAAGCGTAAATTACCACCTGTCCGCAATAGAAAGAATCTACGGAATATACGGAATATATTGATTGTAAAAAAAAaTGCGGTATGCCTGAAGCATCGGATAATAAATATATCGGGAATTCCCTGTCAGACATCTCATTAAAGATTATCGCTTTACCGATATCAGGGATAGGAATGAATATGAAGATTACAACCTGTAATCAGTTTTAGAAAACTTGTACAATCCTTTTTATTTCTATTATCGTTTTTGTGTATTTTATTTACCGTTGCACTTGGTCGCTATATCGGCTGCCATAGAATCCAGCCGTGTCAGTGTAATCTCGCTACGTGTTATCTAATCGACGGCTGCAACGAAGAAATCGATAAACCGTTTAAACGCATTGTCACCTAGACGAAAGCTTCGTGTACACGCCGGGCACACGTACATACACGCTTATCGTATATTCGCGCGATGGCGTGCGCATGTACATTGGGCCACGTACCTCTCGATTCTAATCGTATTACGATCGAAATCGTGAAGCGAGCTTTCGTGCCAAATCTCAGAAATCGCATTAAGGTTACGACCGCCCACGAACGAAAAACCCCGCCGTTATGTCGATCGAAGATAATGTCACGTTAAACGAATACATTCATACGTCTTCATAAATCGAACGAGGCGACAGAATTATCGTCGAACCGCGACCGCGATTTACATAAAGGTAGTAATCGCGTCGTGAATTGGATCTCATTCCGCTCTAATCCTTCGCTTCATTTTCACGCCATTCGTCTCGTTGTGAGCGAAGTAGATATATAGAAATCAACTTCGATACTTGATGCGCAACTTCCCGCGTCTTCGCTGCAGCAAACGAGCTTTGCCGTGCCTTTTCCAATGCGCAACAAGTTTCTTGATGTGGTCACGATAGAGGGTCGTGTCTTACTGATGGAACCAGCGTTTCACAAGTGTCGGGACTTCACTGCATGAAGAGAAACCCTCTTGAAAGGAGTCCCGTCGTGTACCATGGATGTAGCACTGACAAGCTCTCGGTATAATTTAATCTTGATTTAACGATCTCGATCGCGCTGCGCACGGATATCTATTTAAAAAATATCGTAAATCGATAAAGGATATCAAGGTTTGCGCTTGCTTTAATAATGGTCGCTCTAAAAGACACTTTCAAAAATTCTTTTAAGTAATCATTTTATCATTTTATCACTCTATCTTGTTATTATAAATATATATCATTAATCTGAAATTTTTTGCATGACGTATATGAGTTTGTGTATTTTTTAGATTTATATTTACTTTAAAGTAAATTTAGATAGCAATTGTTCATCTGAGGGAAATTGCAAAAAATTTTCCAACGTATCTGTTTTCTCCGATTACGCGCAAGATATTCTGTGAAATTAATTTGGATTTAATCAAGGTGAAATTGTTCGATGCATAATGTGCAATTTTGTCATACGAGATTATGCGTACGAGACTCAATCGCCCGATGAATAAGAAGGCCACCCTCTCGTAATGCAATAAAACTCTACCCGGACACGCAAGCGCATAGCAATTTATTGCAATCAGCGTTCTGCGTGCGCCTCGCGCGTGTCCGTCCGGCAAACTAAAAGCAAAAACAAAATGAAGGAATATCAGCCCCAAAGGGTCGACTCGGCTCTCTAACAAAGAGGAACAGATACATCGTGTTACACGTGCATGCGCCCGTAAGTCGATTCGCCGTGTACGAAGGAGAGGCGAAGGTTTCGCATTGACCGGAGCGCGTGCGTGACCAAACGTACACGTTCTATCGCCTTTGAAAGCAATTCGAGGCACCCTAAGAGAAATTAGAGCCGATTTATCTGATCGACTAAGAATCCAGAGTCCCTTGTTTACCCTGGAAACTCAAATCTCGGAAGTTTTAAGACTTTCTTCAATTCTCCTCCGTTATTTATATATCTCCCATCATTTACAGAAGACGGTTAAAAAACACTGTATTGTTTGTGAAGTTGTGGTATTATTAAATAAATTTAAATGGCGTAGATTTTGTGCGTTATTACAAATTAAAAATTAATTTCTTTTGCTGCATTTTTATTGAAAATTTTCAAAATGATTTATTACCTACATTTTTAAATTATATTTTATTCGTTAAATCTTTATATTTCTTATTTACTTGGACTTATTTGTCTATAGGAGTTGAGAAATGAAGAAACAGAAATATATTTTGCAGTATATAATTATGATATTTCTATAACTTTCATTAATAAATCGGAATTTTAGAAGCATTATTTATATACATTTTGTTAAGTTTGATTTCTTAATTATTAAACAATAGTTATAaaTCTCCGAGCGGAATCTGGCTGAGTGTGAAAAGCTCAGAACGAGGGGACGAGAGAGAGATTGCGCTTTGATTTATTCATATTTAATTATTACTAGAAATTTACGGCAAAATCGAAGCATTCACGAAGGGTGTTACACATAGCATTTGCAAATGTTACGCATGGATGCAGCTGCAATGCGGTTGTCATGATATTAACGACAGTTGGCGAGGGTTAAACGAAAAAGTGGAAGTGGCGGAGGGCAGAGTGGAGCGGACACAGTTGGGTCTTCGTTAGTGCCCGTCAATTAACGCGAATCGAATTAAGGAGGTATACTCTTTTCACGAAAGCGGCACGCGCTGCGAAAATGCTCCGCACGGAAAGCACTTCCTTACTTTCCTTGACGCTCGTTTGCGTCGCTCGTTCGTCCTATTCTCTTTATTTTCTAGAGCTATTAAAGCTTGCCGGATGACGACTACCGCATTGTACATCGCGCGTGAAAAATATTGTACGGAAATGGATCCACGGACCATACTGCAACTCGAGTGTCGCACCGCATTATTGAGAGATAAATTACGTATTACCGGATTTGTGGGGAAATAATTACTGATTTACTGGCGTTAATTTAAGCCGTTCGTGCAAATCGCTTTTAATGATCGATCGTGCGGTTGAATAATACCTGTTTTTAAATATCTATCCTATACCTGTTTAATGTGAATTTCATTTTCATTGTTATTTTTAAAGTGTAACACATTATAAACATTTATATCGAAATTTAAATGTTTAAACCTTCAAAATTCAGAATAAAATTGTCGCGTTTATTTATTTAAAAAAGTTTTAAATCTTTACCATATATTTGGCGCTATGTGTGACACGCGCACAAAAAGTTTATACTTTTACGTCACACCAGGAATTCCACGGGTGAAAGGCAGATTTGCCACTTTTGAGAGATTAGTTCTTCGCGTTAATTTTACGAGTGAGGTAAAGAATCAATTTACGTCGTGCGCTCTTTAACGATGAGCTTCCGTTTTGTTAAAACGAATCGGCAGCAGAGCTCTTTACGTCGGTATTCATCAAACCATATGTAAGTAGCGGCGCAAACACAATTTTTTTTAACACGTTCCGTTTAAGTGGCGAACTGGCTTTAAGTGAGGGAAGAATGTGACAAAGAGATACGCCGTAGCTGTCGAAGGAAGAAATCGGACGCGTACCTTTTGTATTCAGCGTCACGTTGTTACATGGAGACGCTTCTTCGGAATGTTTGCTGTGAAAACATGTGTCCGGGTCCTTGCGAACGAGTGAAAGATCGAACGAGAAAGAGAGGGATGGAGGGGGGATAAGCGGAAACCAGAGAAAAAAAGAAGGTGGGAAGAGACGTCGATAAAAAGAGGACATAATTTTCGCGGCACACTCTGATACGCCGGTGACACATTTCGCCTATCGCTTCACGTGTTTTGCAAAGACCTCCCCGTGCGCTTTTGGATTCATTTCCGCATGTATTCCCTCTTTCCCTCGAATGGAACAAGGGAACATCTCGACGTTCCATCTGGTATGGAATTCTTTCAGAAGATCCTTTCTCGATAATCTCTCTTTCGACCAGACAGATGTAAATGTCACCGCGATAAGCTAAAGAAATCGTGCTCGTACTCAACGTGTTTGTTCCGGACCGTTTGTGTCAACTTAGAGCTACTTATAAACCGAAACTACGCACTTGTGTTTACACAGCGGTCCAATGAGTGGTTATAATAACAGGCCATCTTTCATATACTTCCAGAAGATAAATATACAAGAAAAAAAaTCACGATATATTTCTCCTTTTCCCGTTATATAAGGAAAGATTATATTTTTAAATGTCGGAAAAAATATTGCGAGAAATATATCTCTGACGCGTAAAAATAAATTCCACGATGTCGATGTATCTCTCGATCGCGCTGAAAATTTTCACTAGATAGATAGAACATATCGCGCGCAAGTGAACCGTAAAGTAATTTTCAATAAATTTTTGCGCGAGGAATGCCGTCTGTCGTGTCCGACCCATTCGAGAGCTCAGGTTCTTATATCCTGATTTTTTGTTAGATCGGTCCGCCTTCGATTTCGCGACTTCTCGGATCTTCCCCCTCGTGCGAAATTCCGCATTGCGCGCGAATTAAATTCTACGATCCTTCAAAATTCCACCAAAAGTGACGTGCAATAATCAGCCCGATCCGGACCCGTTTTAATGAGTTCTTCTTTCTTCTTTTCTCCTACAGCCACGCTCGCTCCTTATTCGCTTCCGCGTCCAAAGTCCGAGTTCATTATACCTCGATCATTGGACGTCCATTAAGGAATCCCGTCTAATAAGGGGTAAGGTGCGCATCTGCGCGTCGTTACCGAGCTAATTCGTGACGGCTCTACTCCCCTCGCCCGACCGTGTCGAGCATGAGGATATAAATCTGCCGAAATTAATTAGAGTAGGTAAGCCGCAATTTAACGTAGCGCCAACCAGTGCCAGGACAAAGTTATTCGTCTCTTCCTTTCTCTCCATCTTTCTCCTAGCTCACTCCGGAACTCCGTCTCGATCACCCTAGCTCTTATACTCGCAGTCTCTCCCTATCCTTTCCATTCTCCCTCGCATCGCTGCCTACACTGCGTTCGGGGAAAGCTCGCTTACCTACTGCAGCATAATATCCCTTATTAGAACGTGCCTGGTAGAAATTGCGGCATACGGATATCGAAGAGGTGCGCGAGAAACTACGAGCGCCACGGTAAACCTGGGAGGCCACCGAACGGCAGCGATAGCGCGGTGGCGGAGGAAAGGGGATGGTCGGAGTGACGTGGGAGGGAGAACCAGAGAGCTCAAGGGTTGACGGTGGTTTACTTGGCAAGTCAAACATCCTACAGCTTGCAATATCCTGCCCCAGCCGAGCCTGTAaGATACCGTTAAGGGCGAATCGAACGCAACCGCTTTCCCGCCATTCCCCATTCGGGAGTTGCCTCGACAACGAATCGAGGTGGAGCTCGGGAGGTTTAGTCGTGACCACATCAAATGGACGGTACCTCTCTACAGTATGCAAAGTATGCTAGCCTGCATCCCGTGCCGGAGACGCGAAGTTTGCCCGATGTAGGCTTCTGCAATGAACGCGCGTTCGCGCCAAAGCCGATGATGCGTCGGTGGCGTTAAAGCAAACGAGGGAAACTGCGAGTGAAGGATGCTGACGGGTGTATGAAATTGATTGGTGCTCGCTTTGCGCGATCCTTCCCTTTTTATTCCAAAACGCGAGAAAGATTAATTAAATTACAATACGACACGTAATTCCAAACGGTGCTCGCTGAAAATCCCCCTTTCGCGTATCTGTATTTACGCTCGACGAGAATAACCAACGAGCGATATACGATATAAGCGGCGAAACATTTCGTACGAAATAAGCGCGATAATTTTGCATGCATTTTCCATGGTTACGTGATTAATACGGAGAAACTTCCTTTCGACGTTGCGTACCATGATTTCCGCGCGCTTCGCTACACCGGAAATACATAGACGTAATTTTACCCCCTTCCCTCCCCACAATCGTGATACATCATCCCCGCCCTATATATGGGGGAATGTTTCAGAATCCTGGGAAAATGAGGTTCGACCTTTTGCGTACGAACCAGCCGCGTTCACATTATCGACGCGTGCCGCGAGAGTCTCCCCCTCATATTGGCATACTCACACACAGAGATTTCCATTTTGAGGGATCGCACGGGCTGTCGAGGAGAGTAAAACGAAAAATTCCAGACGGTCCGCCGTGCGTACGAGCGAGATCGTTTTCATTTTTTCGCGTTATTTGCCGAAAATAGTTATCCGTCTTGTACATCCCATTTTTATCTTCGGCTGATTTCTGATGCCTATCTCATTAAGCTCTGCTGTGAGATTTAAATTTCTCGTTATAGAATAACGGTGTTAAATATAATTTTATTCATACTGCTCTCGCAAGCAACGGAAAATGGTCCTTGAAGGAGGATGATAAACATGCCGCAACAGGTTGATACTTAATGATGATTGCTGTGCATCATAATATGATGAATATTTCTATATGTTTACTATTATAATAAAAaTTTTTtAATATTTGGATTAAGATTTTTTTCTTACAGTAAAAATGTAACGTCAAGCTATAAAATAATAAAATATTTTAATTTGAAGTTAAGCAGGATTTTAAATTATGTTTTACAATTATATTCACAAAATAATATTATTACCGTAATGTTACAAATAGCAGTTCTAAATTTATTCGCAATAAAAAAATATTATTTACCGGCAGATGGCAGTCACTCTATATATTCGAAAGTGGATTAAAACAACGAATTAAAAAAATATAGATCGAATTTCTAAATTTACAAGGTTAAAGTCGTATTAAAAAAAAAaTTTTCAAATTTAACTTCGACAAGATCACTTGAATCGCGCTGTATCTTTACAGTTTCAAGTATTTCTTATTCCGCGCGACGATCTCCTCTCGAAATCAAATTCTGGTCTCAATTTCCAGGTCTTCTTTCGCTTTCCTCACAAAAGAGACGGCGAAAAGAGGGGAAAAAAAaGAAGTGGCAGCAGATAGCGCGGTCCCGTTCGAGGGAAAAATAAATTGTGCGCCCACCGTCCGTCCGACGGGAAGTTCATGGCAGAATATTGATTTCCGCGAGAGAAGGCTATCGAAAGAATGGCTTTTTAAAGAATACACATGTACACATCTCGATGCATATAGGGTATCATAGAATGTATCGTAGAAAAATGGCTGCAGAAAAATTCATTTAAAAGTACAAATATTGCAAAAATGCCATCACAGTTGCTACTTTTCAGAGCTACTTCTAGTATAACGACAAACGTTTGCTTTTATGTAGTTTGCTATTACGGTATTGTCTACTGTATGTTGAGACTATTATTTTATAATATCTGACAGTAACAACGCTTTCCAGACACCCAATATCTGCACGTTCGCGGGTGTCGCCACGTCTTCGATTCTCACCGCGTCGACGGATGATGCCGTTCACAGAACCGGAAGTCTATTCGATTCAGCAGAAAAGAGCGTGTATAGGATTCCATCCCCCTTCCCTCCCCCCTCCGCTCCTACCCGCAAGAAATTCTTGCACGAGCGACGCCGAAATCGCGATAAGCAGCGAGCCATCTTCACCGCTATTCATTTTCGAGCGAAGGAGCTTCAGACGAACCGAAAATATTTCTCGATGCCCATGCTCGACGCGCATCGAGGAAAATAACTTCCGCGACAATCGCATTAAACTCGTTTAAATCTATAGTCACTTCATTTCTCTCCTTTTAAACTGCCGGGCAAAAATTCTAGTACGCCAATATATCAAATAATTTAATAATGATTTTTCCAGTCGTGATACGTAATTTAAAAAATTAGTACAATTACAATAAAATAAAATATTTTTTACGGAACATCTCTATAAAATACGCCGTTGATTTTTGCTACCACATTTACGTGCATATATCATAACATTTCATCGTACACGCGCGATAATGGGGAGAATTTCTTCATTTTTGTCATAGTTACGGATATTTATAACGGTAGATGTTTGGGATAAGGATCTCTTCCTTTCCGAAGAATAAACTCCCCTCGGGGATTACTTCGGCCGTGTCTTTAAGATAGATTTGCCTGTACGCGACCGTGCTTGGCATGCGACTTACGCGAAGGAGGTGGAGCTATCCTTGTGATCTTCGTGGATATGTTAAATTGATCGTGAGCAATAACAACGGCGAGGAGGTTCTCGCGGCGTTCCCGACCGGATTCCTCAAAAAGGTCGTCGGTAGAGTTAAAGGGCTGTGGCGCAACATAGAGATGCCCCGCCGCGCTGACTTCCACAGGCACATTAATTTTCGACCTGGGACACTTGCCATCCCGTGCATGTTTATTCAATTCTTACTGGATGCTCCGTCGGCCTCCCCCGGACGGTTAACCGACGTCATAATGGATTCCTCTCCACCCACACATTACGTTCTCACTCCTTTTTCCtCCTTCCCCcTTCTCTCTCTCTCTCTCTCTCTCTCTCTCATTTCTCGCCGTGCGTTtCTTTTTGCCGCGGACGAGCATGATCGATGCGCCACTTTAATGAGATCCTTAAAATACGGTAGCGAAGCTTGCAAGCTCCACGATTCTCTACGATTTCCCAGAAACCCCCTTTCACGCTTTCCCTACACCGTGAAACGGGAGCTGTCCGTGAAGCATGTACGCCGAGTGCAAACTCAGACTTCGTCGATTCTCACTTAATACCATCCCCCTTCTTTGCTTGAGTTAGCTGATTTAGGGATGCGCCGGGAGACACAAGGCTTCTTTTAGGCGCGTACTTTACTTACGACGAAGTTTTACGCGGCACTTTATTACCTTGCTCATTTTACGCGACGGATCGTTAATCTAATGGTGTCGGCCGCCGCCCGGGTGACACGTGCGTATTCGGAAGATAC +>scaffold_2 +TTCGCATTTATTTTTTtCCTCCCCTCCTCCTCTCGTTTCGATTTTCAATTTTGATTTGACAAATTCGTCCATTGAGATGTATCTCGTACATATACACAACGCGCAGCTTCGTTTTCGTAATTGGTTATTGTTATATGTATTTTTAAAAGAATTGTTCCCAATAGCGAAGTAAAAAAAaTAAACCAAAATATTTTCACTATTACTCTCTCAATATTTATAATTACTCGCTGACTTTTACTTCTCATTTTCTTTTCCGCGTTTCGTTCACTTGGGACACGTCAAGTAAATTGCTGTTAAATCTCTTCTGATGAAATAACGTCTAATCTCACCGGACAGCCCGCATGTCAGTGCCGTTTGTCCAACGAGCGGAATGCCAAAGAAGGGGCGGATTCGAGGTCGTAAATCCGCTTTGTCGGAATTGTCATGACGTAATGAAATACGTCCTACAAGCATTTACGCACGTACGTAGGCGTATAGACAAACCCGAGGTGAGAGATAGGAGTTGCCTCGTATTTACGATGGCAAACGCTAATTCTGCAGAGTTTACCGCTGGTAGGACTGACTCGCGCGCGCGTCGGTCCCTCCCCGTGATACCAATCCCTCGCTCGATCAGCGAAGGACGCCCGGCGCGTTTATCTTCCTCGTGGTAATTGCCATTGGCGTTTTTTTTCCATCTCAAGATTCAATCCACTTCGCTGCCATTCGCGCGTCACGGCTACCGGTTTCTCCTCGCGAGAGCTGAAACGCCCGCATGATGGATGAAACGGCTTGGCCGCGGTCGCCGCCGGCGGATTGCGGAATTTGCGCGATCGCAACGTTGTTtAAGGCACACGTGGCGCGAAAAATAaTTACTGAACTTCAAAGACACCGAAATGTTCTCGCGATTGAAATTACCAGTTACCGATTAGTCGATTCAATCGGATTGCCGCGTGAATTTTAAATTGCACCGATGCGAACGGCGTTTTCAATCGCGCGACGTTAACATTTCAAATGAAAAAAaTTCTACATTTATATTGTTTCGCTCCTATCGTTGTACATTATTTTACTTCAGCTTGATGCTCGCAGCGGCAAAAaTTCATTAATTAACTTCGCAAGAATGTGCGTGTTCGAACTGGAACGTCAATGCGACTTTGTAATTAAATTGTTCTTCAATCATTTGACAGCTTTGATTTGTAATTGTAACGCGATTTCTCGTCTCGCGGCGTCTCGTGCGAGACTATGAATGCAAACGCGTCTGCATTTCCGGATTAAATTTGCATTCGGTACTTGTGTTTGTACCCACCACGGCGCCCTACATTACGGCGCCGGCTTTCTGAGCTACCTACATGCACTTAAACGTTCCGGCTACGCCTATTGGATAATTTACGGCCGGCTGAGCATACTGAGTGATGCGCAACACGCGGAGTATCCGCGCTACATCCCCGTGTCACGCGCGCGCTTTGCGCTTCGAAAATCATCGGCGGTTTTACATCATGATGCAAATGGCGACCCAGTTTTTCTCCCTCGCATAGACCGCGCGGCTGTAACGTGGTTTCGTTTCAAGAGGAAATTATCGCTACGTGCTGGAGAGGAATAACATCTTTGCGTCTCTGCGCTCCCTCGTCGTCGTCGTCGCGTTAAAATAACGTTTTCGCACGCCCGCCGCATCACCATGAATATTTATGCGCGCGACAGGTGCTTGAGAGCTGCGGAATCGAGCTGCAGTGGCGCAACCACTCGGCGAGTAGTGGCGATGAGCAAGGAAGACGTGCCCGGTATCGCGCGCTCCGTTCGTTACTCCGACCCTAATGGAGCCTTAATGCCGAAACCCTCACGAACTTGGTCAACGGCCCAGCGCGTTATATACGCGCGTTTCACTTCATCTCGCCGCTCTAATTATTGCCGACGTTGCAATTATGCCGCGCGGCGGGATCGCGCGTGACGGAAACGGGACGTAGTTAATTTTCGGATGTGGCCgTtTtCATTATTATCGCGAACTCTCAGGCGTGTTTCCCGCGGTCTTCCTTCTTGTTATACTCCGCGAGCGCGTCCCCGACGCGCTATTCATTTTCATTATCAAAGGGCAGCGCACCAGCTTCAGAGCTTTCGAGCGACGAGCGAAATGTCTTTGTTGCAATTTGCCGGTGGAACGAATTACTTCAGATTCACAGAAATTGATTCACGTTATGTTGGAGCACGGTACAATCACTCGTTTCATTCACAAAAATAATCCACTATCCTCTCAAACAGTCCTTGAATCTAAAGATAATCAGGAACTTGTGTATCAGACAACTTTATGTCTAATTTAATCGTTTAACAGTTTTTCACAATTTTTTCAGATATATATTTCCAGAAAATATGTGTTGATTATCTGAAAAAATTGAAAAACTATTGAATAATCAAATTATCAAATTATATCTAATTCAAAACAAAATGAAAATGGATACAAATAAAATTTTTCTCTGATAGATGGAAAATTTGGTAATTTATTATTGACTCGCGATAAAAGGTCAAACAGCTCTTTTCAAATTTGAATGACAAATGCGACTGAATTTGAATTACGCAGCTTCGATCATTCGAGTAATCATAAACCCCAGAGTAACAGCTGATCCCTGTGCGTTGATCTAATCATGAGCTTCTAGGTGTCAATCTGTGCTGCCTACTAATGTTGTACTTGTATTCCCCGCCcGCCCCTTGCCGTGTTGTTGGAGGATGCTTGGACTTCCTCCCCGCCCTTACTCACGGCCTACATGTGGTGACGTTTCCCGCATCGAGCCCTAATCTCTGTATCGTAATGTTGTAGTTTCGAAAGGTTGCAGGGGAACGCCAGAGGGAGGAACTCAGATGGGAGCGCGACCTGGACCGGAAGAGCAAGTCGAGGGGCGGCTCGCCCGATCGCCATCAAGCCTCCGATAGAGGGAGAGCGACCAGCCCTCAGAGAGTCGTCATGCCGACCCAGGCGGGCGGTAAGGATCATTTTACTCGTTCGTACGAGATATCTGTTGCTCCTTCATATACCGCAGACGTCACATTTCGCGTAACGACCGCATGTTACGATACAATCGAAGAAATAAGGAATTGTATATGTGGCTCGTTCTTTTTAATGGCAAAAAACGGAGTTTGTAATAAAACGCTACAATATTACTATTAATGTAATATTGTATAATTAGGCTTGTTCTAATTTAATCTAGATAGATTATCTTTACGGATACGTTTTAATTATTTGTTAGTTTTAAGAACAACGTAACTTTCTATTCCATATAAAAATCTTTGCGAATTAAATATATATTTTCATAGAAACAGTTTTTtACACTTATAAATTTGTAGTTTTGTTATTATAATCGAGCAATTGGGCATAACGAGGTTTCCAATTATTTCTGACCACAGTCAATCGGGAGATATCATTCGAGATCAAAATAAATTTCGAATAATGTTCTACGTTAACCGCGTTGGATCGCGTCATCTCTCAATTCGCTTAGCGCGTCAAACTCTAACGTCATCTTTCAATTTCCTTGATAAAGCGATCGAGCAGGAGGGCGGTGATCTGGACGACGAGGAGGAACGTCGACGTCGCGCTCGTCGTGGAGGTAATACAGTTCGCCGTAAGTCTCGCGTGACCAGGCAAAGGTCTTACGACGATGAAATCAAAACGGCGGCCACGATGGCTGCCGGTGGAGCGCAGCCCACGCACCCTGACACCGGCCTAGGACTTCCGGTTCAATTACCAAGACGAGCGTCTGCCTACGACGTTTACGCTGTGCCCGGAAGTAGCGGCCTTAACGCAATGGCCATCGCCGCCGCTCAACAGAGAGCCTCCATTTCGGCGCAAGGTGCGTTAAAATGACTTTACTGCAATAGATGAGAAATTTATTCTTTGATTTCTGAAAGAGCTCGCGTTTGTAATTTAATTACGCAACGCCGTAATAGCCTTTCTTTTTACAATTGAAAGTCTCATAAAAGCTAAGCAAGTTAATTTTTAGGATAAAAACTTCTCATTTTTTAATTGACGATTGTATAAATATAATAAATTTCCTTGGACATATAATAGATATAAGAACATTGTTTTAGAGTTTGATTAATATTTCGAGGACGTTCCATTTTAAAATAAATTATAAAAGAAACCTCTGGAAACTCGTTTGATTCTTGCCGGAACAAAATGTTCACCATGTGGCGCTACTGACGGAGAATGACTTGACGCCATAAATAACTCGGATTCTTTAAAAATAAATTTGTTTGATTTTTGCGACTTCAATTATACATATTTGAGTATGAAAATGCGCAGTATAATACGTGAGATGAAAGACATTTTCTTCTATTAAGTCTTGCAACAAAATGGTCCTCTGTCGAGGTACTGCGAGCATGCAATATTATGCACATTAATATCATGAGCACATTAATATCATGTAAATTTAAACACAAAGAAGTTTGATTCAACTATTTTTTTCTtAAATATCGCTTTTACTCGTGATATGTAATACAGTGTGCGTTAGAATTAATATTTTTATTATTTATGCTTCACACACATACCTAAAATACGGAAATAATTTCGATAAATTATTCCTCAGAGGTACTTCCAAGACAACGGGAGACATTTCTATCGAATATTGGTATCGTGGTCGTGCTGCACATTACATGTACACGTAATTCCTCGCAATTTCTCTCGTTAAAACGCTATCTTTGACCTCTCCCAAGCTATTCTCGGGAGGAAGTTTAGCAGCCGGCTCTTCGATCCTGGCGAAGGCGCCGAAATTTCCAACTACCCCTTCACTTCCCTCCCGATAGCGAGCTAGCTGGCAACACGTGCTACGATTTCTCCACCAAATATTGCGCGTTTACGAGTTATCGCAACGGCATCCGCGGCAAGTTAGAGACGGCTGCGCGCTCTAAGGGGGCCCTAAGGATAGCAAAAGCTGCCGACTAAGGATAATCGAATAGACCTTGTCGAGCAGCAGTAACTCTACCGTGTGTATTGCTCGTTCTTGTTCCATAGATATCTCCGCTTCCTCTGTTTCGTGATAGAAACAATTCGCTTCGTTACGCGAATGCGGGCGTCCTGCCCGGTGTTTCACCCGTCAAAGGCGAAAGCAACTCCGAGGAAATGAGTAAGCCGATTTTCGCTAAACAATATTTTGACCGCAACGATGCCTGACCTCCTCGTCCATTTCGCTCGACATTTTCCGCCGCGAGGAACGCCAGCGACGACGGGAACTCTCGATTTACAAAATTTTCAAACCGCGGCTTCCATTTTAATTAACTTGGCGAACCTCCCGACGATGAGAGAGGGGACTCGTAATTTAAATGTCTCCAAACGACAGCTATCCGTGTTATGCAGTTCGGAGGTAAAACTTTATGAAAATTTCGCGTAATGCATCAACAAATTGTTGGTAACCAGTTGTTGAGGATATCGTtAAAATTTCCCGCAGGGAACAGCTTTAAATAGCGCACCGGGCGAAACTAGTTTCAGAATTCCCATTTTCATGCATTCAATtCAGTCGCGTCTGTTGGACGTGTGTCGCGTATCCTGAGATACATTTCTATGACTGTGTAACTTTAACACTGTGCGCGCATATTACCAGTCTGCGTGATCGGAAGCACTAAACAAGCATCTCAACTCGACATGGAAATTCCGCTTTTCTCTTTCCTTTCTTCTTCCCTCCCTCCCTCCTTCCCTCCTTCCCACTGTCCTATTGAAAGGCCTTGCACGCGGTGAACTTGCAGTGAACTTTCTGCGGAAACTATTTTCGATGCGTAGGGACATATATAACGCGATTTCAAAGCCATCAGTACTCTCGCATACACGCATTGATCGGCTATTCGGATGCTCCTAAAATTTCCATTTTGCCGAGCGTAACGTGTTATAGCCTCAATTCGATACTTGGCTTGATGTAACGTGAGTTTCGCTCGCCAAGGGGCTGATATCGCACAATGGATACAGTAAAGCAAACTTGGCCCAGTCAACTTGACTGTCAAGATCGGGTTTTGCATAAATCGAGAAGCCAAGCGAGAAATTCGCTTTTTGAAGTAACTCGGTAGACGTTTAAGAAGACATATTATAGCATTGTTATAATATCGCGTTACAGTCTGAAAACTGATAGACCGTACCTAGATAAAATGATATAGCATCTTCAAATAAAAATTTTATTTTCGTACAAATTTAATTACCGATTTTATTATAAATTCTCAATTTTTAACATTAAGCAGATTAATGATATAAATTCAAACTCAATAAGAAACGAAGATCAAGACAATAAAAAaTAAGATTTGATTATCTAATTATTAACCACGAGATATTAAATTGTCGATTTTTTTTtATTTTCCTCTTCCTCTCTTCAATCAGCTATAACATTGTTTTAATGTTGATATTTCGCACTCTCTCCATTTCTCTTTCGCGGACAAACAAAAATCTACCCCCTATTCGTGCGACCCGTATATAGTGTGACCTACACTTGTTTCCCTACACAGCGGCCAAGAGCTGAAAACTCCACTTTCTGCGTTACAGAGAGAAACAACATCGGCATTCGACCCGCATCGCACTTTGGTGTGAAAATAACCATTTTGACTATTTTATTTCTTCCGAATATGTTTAACTCCTTTTAAAGTCTTTGTGCGGTAACCGGATATTTCGATATTCTGATATCGGCTTTTtCGCGAGCATCGTTATTACTCGGACACAGAGGAAATTAAGAAAACAAATATGTAAAATTCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTtATATAATTGCAATATGTTCTGCGTCGCGCACGTTTTAATGATTAATAAAAACaCATTTCTGTGAAAAATATTTCAGTTGTAGATATAAATGTACGGCATCGAAACATTTCATCCGTAAAACTGATATGTCTCAATTTTCCGTAACACATTACTATCTATTATAGTTTATATTTTTAAAGTTTTACGTTTTTATAGCCTAACTCTCATCTCTTCCGAGCGTATTAAAAGAAAAAAAAaGTTACGCTACTCTTTCATCTGCACTATTATTATTGCATTAGAGGACCTTTTTATTCAAGGCGATTTTACCCGCTATAACGGGTCATATTTAATATTTCAAGTATAATATGGTTGGCCTGAAAACGTCGTTGGTCGTCTGCTTCTTCGCAGGCACCCGAGAACCTGAAGAGCGGCCTCGCAGGTCGTCCTTCCGCGCCGTGAAACCGGTGATGCCCTACGACGTCGCAGCCGACGATGAGAAGATGATTAAGCTAGACTCGTCATCTGCACCTGTGGTTGCACCGCCTGTGTCCCAACCTGTTCTTATACCCGACGAGGAGAGGCGCAATCGACGAAGGGGCTCCCAATTGTAAGTTATAACTGGCGTTATATCACATGGATTTATTGTGCAAAAGCATGACCGCGCATCTCTTGTTTCGTAATATAGTGTGAGCAAAGTGAAGTACACTTCTTATTAAGATGTTAAGTCATACGGCTCAACATGTTGAAAATCATCTTGACGTTTAACTCCAATGCGACTTAACTCGACATCTGTTGTAAGTGATAATATTTCTCGCAAAACCATTTCTCATTTTGTTATTATACAGTGAATCTCTGTAACTATTGAGCAGTTAAATATATACAGAGTATGTATAAAGTCTCTTTCCCATCCCCTATATTTCATAAAACGATAAAAAATTATAAAGTACTCTTTTAAGGGAGTTGAGAGTAGAGTGCCTCTCAAACACGTATTTTTCGTGACTTTCCACAATTTTAAACCGTCTGCGAAATACAGAGGATGAGAACAGACTTTATAGACACCCTATATATCGTTGCATTTGAGTGAACAACACAATGTGATAATGCAATTAATTCTAGTTAATTTTAATTAACCACACCCAGCACAGAAAGAACATGACATAGATAATCTCTTATTATTTTAATTAAGATTAATGAAATTTTGAATATCATCTCTCTAGTAATTCAGTAACTCTGGAAATTGAAATAAAATCTGCAGTAACACGTTCATATTTATCATTTCGGCTCTTTCTAGCGGAAATGACGTACGCAATCTGCCAATTTCAATTTCGTACTTCAATTTCAAATTTCCATACATTCGTTTGTTTTTTGACACCAGAATTTTGACGTCGAGATAGACATTTCGTCCCTATTTCGCAAAAGTAATTTAAACTTCTACATTTGTCTACGTCAAAAGAGACCAGGCTTTCACTTTTTCGTTTGTAAATCAAGTATTTCCCCATTCAATACCAAGCTGTTTCAATTTTATCTCTGCGCGTCTATTGAATCGTCTAATCTAAAAAGAGTAAAAAACGATTAATAAACGCAGCAATTTCTTCAAACCGCGCAGGACAGATTTTACTGTAAATTACGTTTTTAAATTAATTTCTGAAGGTACGTTCTTTAAAGGAAATGTTCTCAATGTATACTTTAATTCTTCAGAATATCCTTTCATTTAACCAAGTCGCCATTCCCCTCCAATTAAGTATATATTCGAATTTTCTATTGAAACATTGCACCGTTACAAAATCCGATTACCTTTATAATTTTAGCGGTATACGTTGCTCGCGTGAAAAACATGTAAACTGGAAATTGAAAAATAAATCGGCGTATCTCGAAATAAATCGTTGAAATATTTTTTCGAACGAGGACGTATCGATATTGCGCATAGCTTTCACAATCCGCAAATGTTGGTCATATCGATTTTATGGAAGAGGTAATTTTTGAGATATTCAGTACGCGAAGTATCTTGGCGCGAAGATCTCTAACGCACATACACATGCGCATATCCAGAATACTCGATAAAGGATTTCCATATTTTCCATAACCGACGTTTCTTGACGCGAAATGGAAGGCTCGGCGACAATCAGTCATAAAATAAAGTTCAGATTTCAAAACACGATAATGTGACGGAGTGGCGTGTAAACTTAGGTACGCGGTCTCGGTCGTTCAATCTTCGAGAAATGTAATTACCATCTAGTGTTTACACCTCATTAAATCCCGTACCAACAAGTTTGGATTAAATAAACCGATCGCAGCGATTCCCTGCCTAGTTTTTTtGTTTGTGATCTTGCTGGTGATGCGGACGAGGGAAAATTTACTTAGCTAAATTTAGCTCTAAACGACCTGTCTTGAGTTtCCCTTTTTTTTTCAGCGAACGAGTATCGATTCGCAATCAACGAAAGACTCTGATATAGAGCCGAACCGAGCCATTTCTCTTGTATCCAGCCGGTGCGGTGGCGAAAATAAAGATCGATCTTCTCGTCCGTGATTTCTCCCCTTTTCCGCCACACCAACGGCTTACTAGTAATTACTCTTTTTTTTTttCTTTTTTTTtCTTAGCAAACGCGCGCGCGGTCGGCGTGCAACGTGTGTTGTAAGCGCATATACGCGCATCGCGAGCAAGAGGTCGAGTGGCTCGCAAACAGGGGGAGTTTGCTACTACAGAAATAATTAATACCACCCTCTACCGCcTCCCCCCCCCCcTACTCTTCGTTAAGTGTGCGCATTTACTCGCGTGCGAGCATCTGCGGTTCTTGCCAAAGTCGAGTTTGGAACTATCACAATTTCGGAGAGCTTAATTTTCTACGCTATAGAAGGTTACTCGAAAATACACGGTAAGCTCGCGATATTAACTATATTAGAGGCTTGCGTTTATATGGTACTCAGATTGGGTTAATACGACGGAACTGCACAAATGCATTTGAATTGAGCAGTAGCGTTTATGATAAATTAAAATCGTTCTTAAACACACGCAACAAACACACGTTCTCCGGTTTTGCGGAAGTATTTAAAAATCTAGATAAATTTTTAAATACCTCGGAATAACTGTTCTCTCCGTGTGCATTTTTATTTCGTTTAAAAATTGTTGTACCTTCCAAAGAGATTTTACTTTAAATGAACATTTCAGTACTAACCGTCTATTAATTTTATTTAACATGTGATCTAACAAATTAATAAATCAATTCTATGTAAAACCTCAGACATGCACTTGCCCAAATCTGTTAAAAAAAAAAaTGTTTGTTTACATTCGCAATTGAAAATCTTTCATCGTTGATGTAAGCTCAATAATTGCGGCCAAAGATTCTTTCTTTGAACATGTTCTACGTGTGAAAGGGTCGAGGGCCCGACATCGAGGGTAAGGAAGTGTCATCCCTCGGACAGGTTGTTACGCTTATACGAAGGGGTTGGAAATGTTTGGCGGAAGGGTCGTGTGTTACGTGATGTATCGTTCTTGTCAAAATTGGCTTAACCTTCGCGATCCTTCGTCGTCATCGTCTTCCTTCCAGCCGAGTGAAAAAGTCCGTGAAGGATGACGAGCTAAAGTCATCAGTCAGCGTTATAAATCACCTAGACCGCGTAACCGTTATTATCTCGTACCGTCAGGTGCCATTGAAAGCCGATGCCGTTGTACACATCAATTCTTCATACTCAAATCAGTTTTGATACATACTTTAAAGATTTTGGTTATTATATTGGTTATACTAGAAATCGCAATATTTTTAGTAATTTCTCTATAATTTTTTATAAATATAATGTATAGGAATTTAGTTTAACGGCAGTACTGATTAATGTTTTAAAATCTAAATCTAATTAAGCGAATTGTAAGCGATTATTGCAATTTATTTGCAAAACGAGTGCTGTTGAAAAATATTTATACACAATAAAAAATAAAATGTCCTAGAAAGTCTCCACTCTAAATTTTAAATTGAAACAACTTTTATTTTAAATTATTTTACCTTAACTTTTGAGTTATTTAAACTTAAAATTTAAAGTTGACTTTCTGGGACATACAAAAATGTTAAAATTACATTTTATTTATTACTGTGTAATCAAAACTGTTGTAAATACCTTTGTACGCCTTCTTTTTCGCCGCATTATCTTCCAAAAAATTGTATCTTGTGACTTATGGATGCTACGCGGTGAGGAATTAACCTGTTTGTCTATCGAACGTGATAAACTTGAACCTGCGGAAGAAAGCTGCACTAAAACTGTCTCTAATGTAATTTGATCCGATAAACGAAGCGTACGTACGATACTTTCCAAAATACACGGGCCGTTTTTACGCCATCGAAAAAAAAGTCGTCAATTATTCACGATCAATGTGTACTATCTTAAAGCGGCACCATTCGTCGACCTCGATTTCGACGTGTCCCGGCGGATCGGCTAAATCGAGAGACGCGAGAGTGGTTGTCATTAGAATTAAAACAAGTGCGCGGTACTTTACTCTCTGGCTtATGTCGGCTTACATCGGCGAGACGTCGTCCGGCGCACTTCGGAGAATGGAAGCACACTTGCGCTTTAATGCGACCTTGCTcGCACTACGTCGAAATTTGGTCGTGCCTCGAATGCCTTGCATCGGGTGACCGTGCGCCGCACCAACCACGATCTAGGTATCGTCATCTCGGTAAACCGCCGGAAATCAGGCTAAATCGTGCCAATAATTCTACTGAATATCGCACCGCCTTAACTGGCATACTTTCCGTTGCTGTGCCAGTGAATTTTCGACCCATCTCACGCGCGCGTCTAGTAAAGTTACATACCTCGCCTTTCTCTCGCGGTAACTTCAAAAACTCGATTCTACAGCGAGAAGTCGCGTCTCTTTTGTGTGACGAACGCTTCTTCACGAATAATCACCGAAGTTTATTGATGTGTATTCTCCAACTTTATAATACGCGATCAGATAAAAATAGCGAAGTGAATTTGAATGGAATTTTTATGTagTTGTGGCTTATCGTGGCAATTATAACTTGTTGAAAGAGTGAAGAAATTTGCTTAACTATCGCGTATTTATAAGAAGAGAAGTGTAGAACTTGCTAATTAATTTGACAAAATTTAAAAATGCAAATTTTCCGCAAAATATTGAAACACTGTAAAAGAAGCTAGCCTAGAGTCGTTTTTTTTTtCTtCCTATTTTAACTACGTGAGCAATTTGCCAAAAGTTTCGAGGCAACAGCGAGAAAATGTAATGACTTACGTCATACTTTCTTCCTTTTCTCAACAAAACTTAGGAATGTAATAATAAAAGTTTTAATTCTCGCTTACTTACGGCCTGTCCGAGCAATTATTGTTTCCCGTAGCGCCGGCCGCGAGACATAATCATTTAATCGTGTAACCTTTTAATTCCTATTTACTTACGGAACTACGATTTAATGTAATTATCGTGTTTCGTTATTCCGCCCTCTGTGTTCATCCTCCCATGCAACTCGAATTTTCATAGAAACTAAAATACGATAATAATAAGCGTGGACACGCAAATTTGTCACAGTCCCGCAGAATTTTCTCAACTTCCCGACAAAAGCAGATTTTATATAATTTGCAACAAGAAAATTTATAACAATTTGTTTACGCAACAATCAATTTCTATTTCCTACCTGCACGTTTCTGAATACTTTTCACAAGTTTTTGTTTTACGAAACGATTTTAGTCCGTAACGAAACGAAGTTTAATATACGTATGTATAAAAATATTAAACGCATAGAAATTAATTTTACTTGCTATCACTGATACATATTGATTCAATTTAACTGTCTGCACGTGCTTTTTTtCTTATAACTCAACCAAGTGCTTTACATTTATCTCAATGAGAAGATAACGCCAAACGTGCAAGTAAAACAGGACTCTATTTTTCCGTAGACCCTCGACAGAGTATGTACTAATCGATATCGCCGCGCAGCTCATTCTTATTCAGCGAAACGACCAGGAAAAGCTTTTATTCTGCCGGAGTTCGTGATGGCACTGCGCAATTAAGCGATTCTCCTTCAAAGAGTGGCTATGAGCTGCGATGAAAAGAACGGGAAGAATCTCATAAAGGGATATGATCTTGTAAATTTCCATCTAGCTCCAGCTAACCCTCGTACAAAACTGAGTGAATGAGTGAGTGAACGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGATCCtCTTTTAAAGCCGACATGTGACATTCCATTGCATTTGATCGAGAaTTCGATATGAATGCAATATATCTTTTCATTGGGAATGAGAGAAGAAATTTTTTtATAGAAATCCAACAAGACGCACTTATTTCTACGATCAAATGTCAGACTATAAATAATATTTAATTGCATTCTGATTCTTGGAAACTGACCTCTTCAATTCCATTTAATTCGTTTCTGCTTAATAGTTTTCTCGTACTTTTCTAGTTAAAAACCTGTTACATTTTGTTGCGCCGGTTACCATGCATGACCTCTGGTCGTAGAGATTTTTTTCCTGATTATTATTCACATCTTTATTAATTTATTCGTACCGCCCACACATAGCTAGTCTTAATTTATGTTTTAAAGGATATATATTTGAAACTCAATGTGCGTATCGTCTGAAGACACAATTTtACAAAAAAAGAATTGTTTTTCAAGAACTTTAAAAATAGGTTTCTTTTCGTAAACATGAAAAAAATCCCATAGTATCTTTAAAAAATATTTAAAAAACAACTGTATTACAACTTTGTTCTGATCAACCATTTTGATGTTGCAAAAATAATCTTGCGTCATTCATAAATTATTTTTTACATAAAGATACAATTTTTCTTTTCAATTAATAATAATTATATATATAGATTTTGATATCTCAATTATTGTTAACTATCAAAATTAGAAAAATTTTATATTTTATATATAGTGTGTACACACATCCCAGTGTAAACTAGCATTAATATAACGTCAATATAATTTTCTACTCAACAATGTAACTATCGCATACAATATGTTATATTCCTATTTGGTGGGAAATAATATTGATGTTATGTTACTGTTAGTTTGTGTTTACACACTTCAATACACTTCTCATTTCTCGAATTTGTGCTCATCTTTTATTCATACATATTTAAACAAACTCTTGCAATTCTTTTTTTTtAAATAAAATTATAATTAACGCCTTTTGTAATTATCGTAAATATATATAAACAAACAGTATTAACTGAAAAACATAATTTAGGACATTTTCTATATGAACTAAAATACCAATATCAAGTGATTCCGAAGTATCTTTGTGCAAATAAAGGAAAACGGAGGAATAAATATTTTTAGAGGGAAAACTGTCGGCAAAACGTCAAGAAATCTCGTCGATCTGGGCGCAATTTTATTCGTTCCCAAATGCGCGCACTTTCTACTCCATCAAAAACACAAGATTCGGGAAAGGAATCAGATGTAGGATTTGCTATTTTTCACTCTTGATCTGCGCGATCGAGATGTTCGTAAAAAGACTTCGCCGACGGCTGTTGTATTTTTATTTCTACCGAAATAAACGTCCCGCACGCTCGTGCGTTCAACGCAAGATTTCGTCAAATCGATGGTTTCATATTTGAAAGGTCGATTGCTCGCGGCAGAAATCGCTTCTTGTCGATACCAGGCGAATTCGCATGATTGAACGTGCTTACAGAAGAAAGAACTATCAATGTAAGATGAAAGGCCGGCTATTTTATCCTCTAATACGGCGATTTCGTCTTTGCAATCGCTGCTATTAATAACAGATTCTTTTGAGAATCTTCCGTCAATTTTTTGGCGAAAAATTGATAAAAGTTAATCTAGCTCTGAAATTATTTGATAGTGAAAAAAAAAGCATTTTTATCAAGCAAAACTTTATTATGTAACGATAAATGAAAGACAAATTTATTTGTTAATTAAAATCAAACGCTTTTTATTGTTTAATTTTATTGTTTAAATTCAAATGGTTGGTATTATTGAATTGAATTTTTAACCGCGATTGCGAAAATCTATATCTGTTTTAAATTTAAAAATAATATAGAATCTGTAACACGTTTTTCCTTGTAGCGATGTAATGAAGAAAAGGAATTTGAAATTGAGACTCCCTTTTTATAACTACATTCAATCGTATTGTGATACGAAACGACAGCTGCAAGTGTAATACTACAAAAGAGAGATTTCAAACGCGATTACGAATTTCCCCGAAAATGATGAGGCATGGGAGAGGAGCTTACGAAACGCGAGACAATAAGGAAGTCTTTTAATATAATATCGCGTTATCAATTCTTTACtATATTTAACTTAAAAAAAAAAAAaaGGgACACAGATAGCGCCAATAATTCTCTGTATAGCTACTCTTCTCCCTCTCTGCACCTTCTCGCGAAACAATTCAATGATCGTGAGCCGTGATCGCGGAGTTATCTCGGTGGATACGGAAATGCTTTTGAGGGGACGAGACTCGTTAAAAGTTGCACGGCTCGTTTGAGATCTATCTCGTTCGCcTCGGAGTTACACCGTTTTGTTCTTCGTTTTCTGTTAtCTTTTTTTTTTttCGGGTCTTCCGGCGTTGCACaTAAAAATGCAGGATAAGCCCAGCGCTGCGGGGCGCACGCTGCCTCAGCCGTCGGCGGAATTGCAAGTTTCAATTTGCAAGAGAAACGGAAGATGCAGCGAGGCGGTTGCATCAACGTCATGCACGCCGCGATATCGTTTGTTTAATGCAGCGCAGCCGCGGGGCTTCCAGACAATAGTTTGTAACCGGCTCGCAACCGACTTATGAATTTCTATTTATTCTGCGAAACGGCGCGATAACTTTTCCGGGTTAAAAGTGGAACGGTGGAAACGCAGTGGAAACGCAGAGATGCGCACGCATTCCTTCGATTCACGCTTAAAGAATACGTCTTGCAGTCTCCTTGTGAGAAAACCGAAAAAGATGTCTCGAACTTGTAGCCGACTTCCTTAGAAGAACAAGTTCAGAGAGTCGCGCGCGGCCACGTTTTTCTTtATAACATGGATTTGAAGAAAATTCCACCAAAAGGGTCACCAAATCTCCGCGATATAAGTAGATCGTCCAATATAACTTCTCAAGTTTTACTAAATTTTAATGGAGATTTCGACATTAACACTGCTTTTCAGAGTTTATGTATTCGACACTAATACTACTTTTCAACATTTAAAAACTTCATAAGTTACAAGTAGAGGGAAGGTAGTACGGAAAGATCCGGCCTCTCCATTTACATTTCGTACAACTTTGTTGATAATTAATATTTTGAATTGAAAACTTAATGATTACATTCCTCAATGTGTTGTGTATCGATTCGAGATTTAAAGTTTTATAAAATATTTATTATTTAGAGTGTTATTTATAAATATATTTTTTCTTGTTTTAGAAAAATGCGTAATTTTATTAAAAAAaCATTGTTTTTTATACAAAACCAATTTTTAAAATTTATTTTTGTGGAAAGACGAGGGACACACATTATCACATTAGTTTCTTCTCTATTACGTAATGTCATCATATTTTTATATCTACAAGAGTCATAACGCCATCTTCCCCTCTACATAGTTTCAATTACAAAATATTAAATCAATATAAATGTATGGTTAAAGTTCACGCTTAGAAACCGTATTTGTGAAGTATTAAAAATATACGTCAGCCACTCCATTCTTTATAAAGTGCAGTATGTACATATTACATTTCCTTAATTATTCTTTAGTTAATAATTCGCAGCGAGTACTTTCTCCCCTTGTCATCACTGCCGCTCGAATTTCTCCTTCACACGGAAAACTTTTGGCACGATTACTTATGTCGACAGCTTTCAATATGTTATAACGCCGAAGCTCATATAGACACTGGAACTACTTGATAGCACGCCGGTGTTTCGACACTTTTCTCTTGACATATTTACGCCAAAGGCCACATTCTTACATTTAATACTGAATGAATCGAAGTCTTCGAAAAGTTTACGTCTTCATAGAAAATAAAATTTCTTACATCAATTTCTAAAAACCATCTTCAAAGAGATCTAACGACATTAAATATCCAATTTAAGTGCACATTGCATTTGCTATATTATCAGAATGTGAACAGAAAAACGTTGGCTTGATAAAAAAAAGATGTTTCGAAAAATTATTCTTAAAaGGTAAAAAAAGAGCCACGAGGATATCAGGAGAAACTGGTTTAGATACGGTCGTTTAACTTCGAAATTTTGATATATCACATAAAAATTGCGCAGGCACTATTTCGGGCAAAAAATCGGATTTGCATATCTAACGCTAAATATTTCCGACGAAATTCAGCACGGAGCTATCGGTTGCTTTCGCGCAAGGTAAGATAGTGGTTATAGCGGTCTACTTTATGAATCTCAAGCGTAAGCTTCCTTAGCCTTTATGGTGCAGAATTAGGACGGTAATTTGTGTCCATGGCATCACACCAACGCGGGCGGGTAAATTTATGGCATACCCGGGGATGCTCATCGCACGACGGAAAGTTTAACACAATTGCGACTACGTTTGAAAGTCCCGTTACAAAGCATGAAAAATACTTCGTTTTCGTTTCACAAAAATAAACGAGTAGAGTGACCGTGGTTTCTTTTTTTTTTtATATTCTCTCCAGTCGCTTTTTCCATTGTTAAAGAAAATCTAATTTAGCAATTAACTGTTTTGTGCTGTTGGAAGTTAGAGACGTTTGATAAGCGCGCAAAATTACACAACTACAATTCCAATAAAAATGCACTACTACAAAGTCCAATTTTTTTtTTtATTGCGCTTCCACGTTTCTTTTTCTTCGAAGCTGCGATTTGAATAACACGTGTAATAATGAGTACTCAAATGTTTAACTTTTAATTAAATGGTTGCAATAATGTGTAGCGCGTTCAAATCGAATTTATTTTTAATTGTCTGCTAAATTTTCCATTTTAACAACTTTACtATTTTTTTTTTTTTtttATTTCCAATTAACTTCGAATTTTATCTAAACACTCAAAGCGAAAAGAAATCTAATATTGAACTAATATAAGAGGTACAAATACAAGTAATAGCCGTTTAATATCACTGGAATCTACGGCTGTTAAAAGTTAATTTTAAAGTCAATATAGTCAGCATATATTAATATTTACCAAGTGAAACAATATTTCTTGGCGGTTTATTATCGCAACTTTAACCGAGAAAGCTGAACGTCGATATTGGATGTAACATTTTTCGAGCTTCGCCCCGAGCGCTGGCTAAATTATTAAACTTGTCTTGGCTATTCCGAGATAGTTTCACAATAATAAAACTTGCTTCAACGTGGGCAGTCAATATCAATCTTGCGGCTTAACCCGCGAGAATCCGAATCCGCCTAATCCCCATAATGGTTATAATCGGTCGCTTAAATTGGCTTACGTCCATGCTCGTGGCAATGGCAGTCCTTAGCGGTTTTCAAAAGGGTTTTTAGTCGATCAATTAGTTAGCTGATATTTAAACATTTGTTTGTTAATGAGTACTTAAAGGGCATTAATAAGAAACTTTCTAAAGAAGTAGAAAGGGATTAAAAATTTTCTGCGATACATTCGATATTTATAAATCAAGTAAGTTTGATTCGATAATGTCAGTCAAGTGAAGTCTTGGCTGTCTCGGTCGTTTTAATTGTTTCCATTAAACATCAATTAGTTATTTCAGCCGTTTTAATTGTTTCTATTAAATATCAATTAGTTATTCTCAAGTCCGCTTCTTAAAATGTCAAATCTCTTTCTTAATTTCAATAAATCTTGTAAAAAGATTTATGATAATtATTTTTtCAAAGATTTCGCATTAACATCACACGGATCTTTTATGTGTTATTTTAGACCCGACATAAATGCGATAAGAGCGTTAACCTCGGCTCAACCAGGAGCGGCAAAAGCTGCCCCTGCGGCGGCTGTTAGCAGGGTTGCAGCTGAAGAACGCGAATTGCCTAGGCAGGGAAGTCTGGTCGACGGGGAAGGCATCAAGATCGTTATTCATGACGTCGACAGTGATCTAGGTAAGTTGATACGCCGGAAATATTTCCGAAATCATACAGTGTACGTGTTAATCCTTATCCTTATCTTTACTACCCTTCTCATTGATTATCCTTTATCTCTTAATATTTTTCTATATCTATCCTTTGCTAGGAAAACGCTTGTTTTCAAGTCGGTACTGTAAGACCCTGCACAATGAAGGAATATTATATTAGATATTAGAAATATATAGGAATTAAAATTTTAGAATCAATTTCCTCGAATGAATACTAAAAATAAATAATGAGCTATGTTGCATCTTGTACGACACATTTATATGCTATTCGTATCTATTGTGCTTTACGTTTAATATTCATTAAGGAAATTAATTCTAAAATTGTTTAATTCTTATATTCCTATGTATCTAATATTTCTCTATTGTGCGCAGGGTCCAAGTTCGCAATCCTGCTATTTCGTAAAACAATATTTTTACATGTTTGTTCGCAATGATAATAAATAATTACCTTATCTTCGCGTTTCGTAAGTAAATAAATTTCTCTTACTACACTGAATAGAAAACTTATAATAAAGCAAAATATATAGTATCAATTAAATATTTGGTCAATGTGACCAAAAATAATTTTGCTTTTCTAAATATTTAATAAACTTATACCAGATTCGGTAATATTTACTAAACATTATTTAGAACAATAAAATTATTTTTTtGTTATATTGACAAAATATTTAATTGATACCATTTCACTATACGTTTGGTAGTTATTACCAGACTTTTTTTTCCAGCGTATACTAGATTATGCACAAAATAGATAAGGTTTAACGTTTATCTGATTTTTCGCGAGTAATTTGACGCCTTATTTAAAAAAAAAaCAAATCGCAAGGTTTTGCTATGCTGCATTCAAAATATCACCCGATGTAGCACTATTCTCGTTGTTCACCGAATGTTAAACAAGGATAAAATGGTAGCTCGAGTGACATTTCCGAACGCAGCCCTACGAGCGCAAATGTTATGCGAGGAAAAGATGCACACGAAAGAAGAGTGCGTTTGATCGATCGAGCTAGAGGCTTGCCGGGCGGTGATTCAATTCCGCGGATAACATCGCTTTCAGTTAATCCCGAGGTTTTTGTCCCGCCAGTGATGAAATCCCGTTAATTAGGAAACGGCAATTTAATTTCGTATAGGTCACCGTGGATCCGCGCTTTCTCGTCCGAGGGAGGCCCAAAGTGCCGTGCTCAAATATCGATTAATTTACAGGAAATAACGGAACGTGTCTTTGTGTGTGGGGGTTGCGCGACATTCAATGTTAATTATTGCGCGATATCCAATTTCAGCACGATCGAACATCGGCCTCGATTTGCATAAAGTTCACGCGTGACTTACTTTTAACAGAATCACTCTTCCGCATAGGAGTGGCATTACAATACATACCTAAGATCGATGATGTGCACGCGCACCGATACGAAAGAATCCTCCCCGCTGTCCTGCAAATGAACACAATTAGTCATTTTCACAATGTGGTAATACATTCTCACAGTGAAATAAACTATATCATACTTCTATGCATTAATCGATTAGTCATTAACGTTTATCTTAATAGATCTTCTCGATAAAaTTTTACACATTTGTCGTGAAGAAATTTTTCCTTCTCGCTATATACAACTGGCGATAAATATCCTCTGCTATTTTTTTtACGCGGTTTAAAAATTTGCAAAAGGAGAGGGACGGCCTGGTTGCATAATGTCGCATTAAAATGCATGCGTATGAAGAACTCATGCGCGAAGAGTTAAGATCGCGGCCTCCAATTCGTTCGAGAGACAAATATTGCCTCCTTTtCTTTTTAAATATGTGCAATCGTATACACGAAGCGAAACCGTGAGATTATAATTCAGTCTGACTTTGTTGCGAGTTGAAAAAGTTTTTTCGTTCCCGGTTCGAaGAAAAATCGTGCCACAGCTTCGACATAGTATTTCCCTTGCACGGATTATCGGGCTAGGAGTACTTTAATTAAAACGCGCCTTATGCTTTTATTTTATGTTCGCTCTGAGAGTATATATATTACTGCAGAAAAGGAATCTATTTAAACGCTTTTAATCGATCTtTTTTTTTtCTACTGCAATTCTTGAATGTATATATAATTATAACGGAAAACGAAAAAGTTTAATTATCGTATCTTTGAGATACGGAAAGGTTTCTTCTAATAAGATACTGCGTATTTGGAAGAGTTTCCGATTTAAGTTGATAATGTTAAAAACGGACGTTTGACGTAAAGTTAAATAGTAATTATTTCTTACGTTTGAACACTCGATGCCGATGAACGTGCAACGTAATTTCTAAATATTTATGCAACGAGaTCTGCACAAAAAAAaTaTTTTTGTTAAAGTGTCTAAAAATTTAGCTTCGTACAAATCTAAATAATTTTATTAGACCATCAACATAATTGCGTAGAACTATCAAGTTGGCTGTAAAAATATCTAACATTTTTACAACATTGCTCATCATGCTAGAGCGTCCCACATAATTATCTTAATGGCTTAACAAAAATATTTTCAGATCTATACTTGGTTAAATGTTTAAATGCTTCAGTAAATCCGTTCTTTCCGTGCATAGGGAATTTTTATGTTAGCTGAATGGTTTTATCATCTAGACGAGAGGCTAATTTAATTCGGTCATGATGCACCATCTTTTTATTGCAGCTGACCTAATTTTTtAAACCTTTCTATTAAAAAAGTACCCATTTTCTCATCATATTTAATTAAAATTACGGTAAAATCACTTTTCGAAGTAGTTCAAATATTGATTTAATAAACAAGTTAATCTTTGATGTACTAATTCCATAAAATATATACCTCTCGAAAGAAAATCGTTTAATTAATAATTTCAGATTTTGTGTATAATTTTTATAATAATTTTCAAATATATTTCTCTCTTGTCACCCATATGCAACAATTCGTTATAAAGTATTAGAAATAATGACACCCTCTTGTCTACCACTCAAATAGTATTCCGCATTTGCACCGTTTTTAGGCCATTTTACGATCGATTTGTTAGCGTAATGCAAAAAAAAAAAaCGTGAAAACTAAAAGAAATCGTTTCACACGGCGATGTTGTCATCTCTCATCGCGATTGATAAGAAATCGACGGTCGACAGAGGACGCTTGAAAACACGCAAGAAGCTTGGATCGCTGCCAACGCGTTTACAGTTTACCGAAGATATTATCGCGTCGACCACTAGACGCAATATTTTCCTCTTCACTTGCGGGTCACCGAGTTACGGCTGCAAAAACGGACCGTTTCATTTTTTTCGCCCGGCAGGCATGCAGGCAACATCCCCCCTCGCGTAGGTCCGCGCGCAATATCGATTGCAGTCGCAGCAGTTATCGCGATTTGACACGCCATGCAAGAGCTACGTGGGAATCGCGATCTGTCCACGTGTTCATTAACGGCATGTCGGTTGGAAGGCAGATTACGCCATCATCTATCTCGCCGATAAATCGCGATGCAACGAACGAACTGCGCATGAGATGAAGAGAGTTAAGTTAGAGACGCGAGGGGGTGGTAGGAAGGCAGCAGAGAACGAAGCGGGGGTGCGAAGATAACATGTACTTTTCATGCTAAAGTGATTGTATGTAATTTTGCCGCGTGCAAGCTCGCCGCTGCGACGACGGCGAATAACGCAGTTTGCACAGAGTCGTTTGTTGAAATCGTTAGTGGGTCATGTAATTGATTTATATCTCGCGACGAGAGACAGGGCCTTTCCTATGCGATATCTCGTGATGAATTAAAGGAAATTTACAAGGACGCACAGTGCTTCCAAATGCCTCTGAATCCGATAAAAGTTATTTATACATTGTTTATTCTAATTCTTTTAATGAATTTTGTTCCACTGGTTTGGTTAACTTAAAATTAAAAAAAAAaCAAATAATAGTATATCATAAAGTATAAAGTATATCATAACGTTTTTAACTTATTTTAGAAATTATTATCTGTCATCAGTATTAGGAACATTTTGATCATAAGATATGGTTTTATAGAGCGATGACATCTGTTATAAACGTTTTTTCTCTTAATTTTTATTTGAAGTTGGTGAAAAAAAAATGAATAGATCAGATGTTGTTACAAAGTTATTACATTAGAAAGTTAATAATATGAATGTTAATAGCTTTTCTTGAAATCTTGCAAGCACGATGTCTCATAAATTGTCTTAAACGTTTATTCTTAATTTCTTTATGTTCTTCTGACATTTGTCCTAGATATTATATTACTAGTTAAATATCTCTGTTATATATTTTACGAGAAAAAGAGGACAAGGCTGTGCAATTTCTACTTTAAAAAATTTGTAGTTTAAACTTCAGGCATTAAAAATGAGATATCGATCGGGCATCATCGGGCTTATGATTGCATGACTTGTTGCATCAAAAGTAATAAATCACATTAGAAATAAACGTCGTCTAAATATCAAATATCACGGCTTATATTGATTAAAATTTGTTACTTTTGTATAAATTTACTCAAGTAAAATGGAAACAGATATCATATATCATTTCGTATCTACAAAAAATCCCAAAAATATATCCTAAAAAATATGCTTCAAACTTAGTAACGCTATAGAAAAAGTACTTTTAATATtTTTTTTTtAACAGAGAAAGACGATAATGCTTCCGGCTTTTGTTGGTTCTGTAATTCTTCGATACAGTACAATAAAATTATTATAAATAATTGTTAACGATTGAAAACCCAGCTTTTATAAGATTCAAACCACTGTGATACAATAAAAATATATAGTCACAAGTACGTGTAAACTGAAAAATTTGAATTATTTTATTATTTTATCATTTAACAGAGATTACATCATAAAATAAAAACATTTCATAATTTAATTATAATACAAGGGTTGCTTCTCAAAGCTGCTTAAAACTTTGTTAAATGATATTGTAGTTAAATCTTTTATATATTATATTTTCGCTACGTATTGAAATATCGATATATTAATCATATAAATGTTGCCTAAATAGAAACAAATTATTAGATATCAGATTAATTATATAACGAAATTATACTTGTTGCTCTGGCAAAATTGCGCTGTAAGATTTTCTAAGCTTCTTTCTTAGCATTCAATACATGACAAATTAATTTGCTCATTAATTTGTAATAATAAATATACCGCAATGAAAAGAGCGCGCAATGGAATGATAATTAAGCATTTTTCATGCCAAGTAATCGTACAACATTCAAGCTCGTCGCAGCTAAGCTGCTAATGAAAATCGCGCAGAATCGCGTTTTACGACGTTTTTCATTAAAATTAAACCGACTTGGAAACGCACACAATTAAACAATTTCTTTACACGCATTATAATTATGTTAGGGAATTTCCTATTCGCCAGGTTTTTTTATGCATAAATTTAAAGAATAATTAAAATTCATAAATATTTAAGGAAAAGTTATTATAACACGCGCAAAAAAGAATTTTAATTATCTCCATAATGTTTATATTTATATAATATACTTTAATATTCTATGCTTTACAATATTATAATTCTTGGATATAATAATACAGTTCCAAACGTAAAAAACAGTATTTTCTAATTGTTTCTGATTTTTTTATCAATAAATCTATTTTCGTTTCATATGATTAAAAATTTATTTCATTTTCATTTTGTCCTATCGATAGATTTCGTCTCAAATTTTCCCGCGTATCGTCATCTTCCCGAGGCGATTGTCGGGGTTTGAACGTAGAAGGGATGTAATCTGGGTTGTGCCAAAATCGCCTTTACGCTACATCAAGCAGAAATCGCCAGGGCGCATTATAAAAAAGGAATTGTTCGAAAATCTCGACCGTAATTCACTTCGCCTCGCTTTGCGACCTTTTTATAGCTCGCGTGTATTAAACAGAGTTTTTCCGCTCCCGCACAAAATGCAGCAACTTCAGTTAAGCTTGTTTCCTTGCAGAGATACCGATTTATACCGGCGTATGTGAAAAATGACTGATAGATATTACGTGGCCGTAATATCTATCAGTCATTTCACCTGCGCTGCAATCTGAAATGATGACTGACAGCGTTAGGAGAAATTCCATTTCTTTTTGAACCGCGTCATGTCATAAACTAACTCGAGCTGCATGTTTCCATTAAAATAGTGATTAGTTTTATGATTAGCCCGCTCTTTACTCGTTCTATAATTAGTGGAAATATTTCAAGCTATTTTTTTTCAGTCGTAAGCACACTTCAATTTGTATTTCAATTTCAAGTTTCAAAAAATATTGGTTTTCTCTCGCACTTTTTGTATATTTTGTAAATTTTATTTTTAAATTAGATTTATTGCAGTTGTTTCGATTTCTGCGAAGTTAGCCTTATTTCTCAGAATTTTGTTACGCTGGTAAAATTCCAACACTTTTCCTGGAAAAGTTTTAAATAACAATGCTGTTGTATTGTGTGTTTCAAATCTTTTTGTGTTACATTATCTTTGCTTTGTGCGTGCACATATTAATACTGACGTTTCTTACTCATCAAAAGGGTTGAAACAAATAATTTACTGTGTGAAAATAAAGAATATTAAGAAATTAAGAATTAAATAATTAAAAGACATAATTATTATAAAATTGTAGAATTTCAAAATCCTATCTTTCATATAGGAAATATAATATTCATCTGAAATATAGAAATGATAAAAGATAATCACTCCCTATACCTGTGCTAAATTCATAAACTTTTTGGCGTTTAATTTGTGATTAACCTTTATTTTGTTATTCACATTTTTTtGGACATTATTAAAATATAGAAACCCGCCGGTTAATTAAAATTAGTTAGTTATTAATACTGAGTTTTAAAGTTGCCATGTATTTTGTATCTTTCAGCTCCCCGGATGAATGCGAAGAGAAGGGTAAAGCTGAGGAGAGATCCCGTCATGGATAAAGGACACAGAAGTGAGTATATAATTAGATAACTAATTACTACTGATTGAAGCGTCTTCGATGTGCTTAAAACTTGAGATTCGAGGAGTGTCTGAATTCGCTCTACAAACTTCTATCGATCGGTCACAGTTCTCTCCAACACGACTGATACCGTTGATTTATATATCACCGGCACTTATTATCGCGCAGACAATGATAGTGGTACTTCATGCTATCTCTATGGTCTTGAATATTGACTTTTCATACCAGTTACATTGAAACTTTCGATATATTATTAATCATGAAGTGTGCGAGCGTTCGCATTTTGAGTAAACTGTACTACTTTCTTTTATATTTACCAATAAATACGTACTTTGAGAAAAATGTTGATACTAGAAAAAAAAAAAaCaTTCTTTGATATATACTGCAAACATTTCGTAAAGTGCACTTGTTCAAGTACTGAAATAAaTAAAAAAACGaGATACTTGTTTATTATTTTATTTCATATAATTTATTATTTTATTTTGATTAAAGATTAATTGATACCGTAGCGTGTTTTTTATTATATAACAAGAAAaTTTTTTGATCTATTTATATTATCCGCTTATATACATTTTTTAGTCTTACCTTTATAATAGTATCATCATTTCACCTTTAAGCATTATCGATGTCGTCGAGAAGAATTCAAGTAAAAGAAAAACCGTTTATAAAATATTTAATAAAACTTTCAAGAAGAGATTACGTGATGTAACACGTATCTAAATGTCAGGGGGTACTTGCTTGCGACAAAGCGAGAGATCAAGAGTTCCATCTGATAATAACTAATTATAATAAGAATAATGACGTTTCTCGAAAAGACGGCTGTATTACGCAGAATAATCGTTCGCTAAAGGGGTGCAACAGGTTCGCCGTGCCCGGAGTGATGGTAATCGAGAGATTAACGAATCGCGAGGTACTTTGATAGGATCCCAGTTAATCAGTAACCCGGGCTGCGACACCATTAATCTTTTACCACTCTCCGGGGAACTTCATCTCTCTTTGTCAACCTTTCGCGCGCCACTTCCTCTTCGACTACTTCCTCTCGCTTATACTTTTTGTGTTTACTCTCCTCATACATTGTCACTTGCCACCCCGAGCCCTTTGCGTCTATTCCACTGTGACGTTTCATCTATCGTTTCACCTTTACATTCTCAATGAATTATGTATTTTCGTTTCTACCTACGTACACCCACACACTCGTGCGAGGTTTAATCAAGAATTTAATCTAAGATCTAATCACATCCCTTTTTAAATGAAGAGAGAAAAATAAGACAGATCTAGATTCCAGGAAGTTTTATTAACATCGCTGCCATAACTGTCTCGACTTATTATCGTTACGCGTATCATCTAATCTCACATCGCTGTATACAACGTGTTTTGTCGATGTGGTGCCTCCATATCACACGGAGCTTGTCGATGCAGCCAACCGTTGCTCTAAATGGGTGACGGCTTACAGTTATATCAACCGTTATGTAATAGCTACTGCCACGACGTGCGGCATATGCGTTAGGTAAATAGCCAGGTAAATGAGCGAAGATGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGGCGGCAACGGCTCTAAGCCTGCGCCCGACGAGTAGGCGTGCGATTGACGTTTAATTATTCGTTGCGCATTCAGACGCTTCGTTTCCTCTATAACATCGCGCTCGCGTTCTCGTCGTTTCCCCGTTACGACACAGCGACGCGGCAAGGGTTACCGGAGAAATTTACCGATTATGTTTCCGCGAATATAATTAATACAAATGCACCCAAAGAAATTGCTCGAGACGATCGGAATGCCAACGATAAAAACTACCGCGGAGCCAATATATTTGAGACTTTTACAATTCGATCAATGATTGATAAATTCGTGAAAATTAGACGATCAATCTCTCGATAAATCCTACGCTTAAGTTATAATTAGGCCGAGATTGAGCTTTGTCACGAACGTTTCTGCAATAATAATGTCAATCGATTCGTGGCTCGTCTTCTGCTATTTACATATTTCGTCAGCCTCGCGAATTTCGCATTGTTATACAATTACCGCGGTCACTGTAATCAAATATTAATATGTACGCTAATATTTAGAACAATTAATGCATTTATTTAATAACATGAAATTCCCGACTGTGACGACCGCACAACCGTAGCGCGAGTTTACGGGCGGTCCAGTGATTCCAGTATCACCATGCGGCTTGTTTAATATCGCGAAACTGCGCATTACACGTATGTTTGCTTGCTACTCTTATTACCCGTTTAAAACAAaTATACAATTTTTTTTTAATTTtATTTCACGGTAATGGTAATTGGTGGAATTTAAATTCAAGACGATATATTTACCGATAGTCATGACATAGGATCATAGCTGTGTGAAATTACGGTATTAAGTTAACAAGTTTGACTAATGTTCATGATAAATAAATCTTATTTTAACTCCAGGCCAATATATTTTTGTTCATTAGATAAAATAGAATTTTTAAAATATTTATATAGTTGTATATTTATATTACTTATAATTATATTTATATTGTCGTTTATATAATTATTTATTAATAACGATAGCATACAAATAGCTTTCAAGGCGTTTCTGAAATCTTTCAATCAATGTTTCCGATTTAGTAGATGCGTTTTGTTTCCACGATCGTTTTCAATCGCTTGTTACACTGTACAATAATATGATTCGTAAAGACAAAGCTTTCTGCCGATCGCGAGCTGATTTGACAAACACATGTCTCCCCACGGCGCCATTTATACGTCGTTTTGTCTTTACGCATGGAACAACACCTACTAATCACGGCTTTATCAATAACTAATCTGTTGTAATCGCACAGAAAGCGCAATAACGATGGTACCACTTCACTATTCGTGCAATCCGAAGGGAAAGCCATTAAGCGCAATGATACGTAATACACGGACGTAACTGGATGTGATTGTAATTCCAGGTCGCAATTTCGCAATGACAGCTTTTCGACGACTGACGACAGGGCAATATCGCGGAGGATAAATATATAATATCCGTTTGCAATCGCTGTTTTCTACAATTAAATTAATCACAAATAAGGCGATTAACAAGTCTCATAAATCATCTAATTAGTTGCGAGTTATTAAATGCTGTCGTGCATTTGGCTTTATTTGGTATTTATAATTTAAAATGTCAAAATATAACTGTTAAGCGCTATCTCAAAAGGTACATATACATTTATTCTTGTTCGTCGCAGTTTTTTTAAAAGTAAAAATTGAATCAATATCGAGAGAAAACATTGAATAAAGATGAACATCGCGTATCTGCTCCGCAAAAATGTTTTCCGTAAAgaaaaaaaaaaaaCGTTTCCATCTCTTAAAaCCGCAGTGGAACTCAACGAACGGACATTCAACGAAAACCGCTGAATATGAAGGGCCATAGGTTCGAACGTTCCATAAATAGTGAATAGGGGGCAAGGGAGGATAACGCGTGCGAATGATCTGTCGCCGCCGCGCACGAATCTAAATTGCAAGTCGCCGACATTTGCACACATCTATCCGCGGATAATAGCTTTTCGTGCGAATCACAGGACACCACAGACGCAGCTGTACTCGCAGACCCCAAGGTGCGCCGATATTCAACGCGATCGATCGGCGCTCTCTCTCTCTCTCTCTCTCTCGCCGCGGCCCGACTCAGTAGAGACGCGTTAACGCAAACGGACATGTCCCGTGTATTTTGCAAGCCTGTTTGTAAACCGTTCGGCTTGGCCGCATATACGAATACGTGTCGATCAATCGCCCAGTTGTCTTGGTCTGACGTGAGTCTCCGTATCTGTGACAGACTTCATATAAAAGCGAAGTCGCACGAGATAAAATAAAATAATCCCAAATAAAAAATTGATTTTACAACGCCATCCGTAATTTCTAAATCATAAACAATTGAACGATTGGCAAATCTAAAAAAAAAAaTTAAGTTTCAAGGATGTAAATAGCGAAAGTTTACTTTTCAATTATTTCCGGAAATAATTTTGGTGGATGAAAAGGCAGGCATATAACCGGAAGAAACTCGATGAATTTAATATGAAACTGTATTTTTGCCGATTAATCTTGCATGAAAGGTCGCAAGAGAATATTTTTTATAGGTAGCAATCGATACGACAAACAATTTGCAGGTGTGATCTATCCATTGCGCGGCAGTTAAATATTTTTGCGGGACACAGTAACGAATAACGTACTGCGAGAAATAACAATGTCTGGAATTAACGATCAACAGGTTGACTATATGGATGCGGCAGGAATCTGTTTTGATTTAATCATGAGAAATGGGGACGTTTGCTGTGACAGTTTTGGCGAATATTGTCAGGCCTGTTTGATCGGGCACAAATACATGAAATAATAGGGCGGAACACTATTATAGCGATATACTGGATATTAGTATAATATATGTGTACGCAAATACACCGAATTTCTTATTGGTGTCGCATAAAATAGTATGTATTTATATTTTATTTTTTTATTTATTTATTTAAAATGTAACGCAAAAAAGTTAGTACTACAATTATGCAAAAAGGTATTAAAAATCGTTGTTTATATTCATGCATTGCGTAAAATATTATTTAAATAAAATTGCTTGTTATTTATTTCAGAAAAATTTAATTTGATTGAAGATTTATGGTATGTGTATTTGCATTGTGTTCAAATAACTTTATATCAACTAAAAGGATTAAAAATCTTATAATTAATGCTGAATACGATGTATACGGTCGCTTAAATCATACTTCATCAATGGTATATTTATCCTCAATATAAACAACAAATTTAATAACAAAAATATAAAGTAATGAGAAATAATGCAGACAAAAATGTAAAGCGTGTGCTTGCTAACAACACTCTAAAAAATCATTGCAAAAATAAATTCAATTTTTCGTTTTATTTCGACGTCTACATCTTTTAACTGTTATTTATTAATTAATATTAAATATTTGACTCTTTTTTGAAAAATTATTACTAAAATATTTTTCTCTCTTAAGAAGGGAAAGGTTATCGACTGATATCCGGGGTGACCAAATTCCGAAGTGTGAAATTTACTACGAGTGTACAAAGCCCACCGCTAATTGATCGAGCGCTTGTAGCATCTACCACTAAAATACTATCTCCGCTTTCTCCTCATCGTAAGGGAAGGACTACCTTAGCAAGTAAACGAGACATTCTTCACGCTCTCCCCTAGGTTCGTGCGGAAAACCGCTCCTAATTCTCTGATCATTCTTACTAAAAATAGAAGAGAAGACCTCAGCGGTCTGAGTTACGTGAAATACTTCAGCTATACGGGATCCCACTCATTCCCAGGGCACGGGGTGGCTCGGTCATTTTCGTCGGTCCTAACATCAAGAAAAGGAGATCCAAAAGAGTATACATCCAATATACTTGGGTCTGCGAGGTCCGGAGGGGTGAGACTCAAACTCCGAACTTCCGCCCAGTCAATATGGCTAACTTTGTCCCTCCCTATGAAAACTCACCGATGGCGACGTTACCGTCGCCTGCGTGACATGGATGGGGAGTCATCAGAAGACGTGCTTCCAGTCTCCAGATCGACCCGCCGTCTCATTATTGCCCTACGTGGGCTCCAGGTGGCCCTTATGTGGCTCTCATTATCACAGCGAAAGCAGCAGTTTTGTCCCCAATAAAGATACATCTACCATGCTCAAAGAGCACAATTTCCTAAAAATTTCACGGGGGAAAAAATGTCTCTACCCTCATCGGTCGCAAGAACGCGCCTAGCAAAGGGGAGGCTTTCTTACCCGCAGGGGGAGGGATCTTAGAATACTCTTTTTTTtCTTATTATTAACAACGGTAACCcATGGAGAGTTATCATTTTCCTCCATCTTCCGTTCATTCCTAGAAGCGGAAGCCACCGATCGCTCATCCTCTCCCCCACCTCCCAACGGAAGACGGAGAAGCGGGAATTCCATCTTCCCGCCGCAGCAGAAaCAAAGGAGCCCAGATGAGCATCTCCGCTCTTCTAAGCTCCCCTACTCTCTAAATTAACAAAGACCTTAATGAGAATCTCAAAGTCTTTAATCTTCTGACCAACAACATCTGATCTATATTCGGAATATCATCAGTCAGAGAAATCGCCGTTTTGAGTCGGTTCGCTCCTTGAACAGCCAATTCAAGACCGCAACGCGCGGTCATGCCACCGGACCTTGCGCTGCAGGATTTCTATGAATGAATCCTCAAAGAAAGAACCCGGTATCTCTAAGCTCAAGCACTTCTGTACGTACCCAAATTCTACTTTGATCCTTCAATCCACGTTGTCGGAACAGAAGCCAGATCAGAGCCTGTCCTCTCACCGGGATTCATAGTCCTTTTGCTGTGGAGCTCGTTGACAACTCCACGTCAGGCTTGTCACGCGATGACGACAGGGACGAGCCCGGGACAATAACTCGCCCGTACCGTCCCTGGGGTATCCGGTCACCTCTCGGCGATAACTTGCTCTGCCTTGTCATCAATTCCATCTAATGGTTTGTTAACAGTGTGTCCATCACCGGAGTTTTTTTTATCATGGTTTTCCTTTCATTAGACCGACTACCCCACTGGGCTAACTAGCCCAATCGCCCTACACAGATCGGTCGAGGAAAAACAGCAAAACCATGAAACACAGATCACGGATAACCCCGATCGACCGCAACAAAGAGGCACGCGCCCGGATTCTCGACCCCAAGAGTATCCCGCATGAGTACGACACAACCTGCGGAACCCGCAACTCCATTACAAATAATGGAGGTTGAGAGCTTGGGGGATGCGCACGGCGATGGCCTGTACGGGAAACTCGAAACCGGGCATCTGGACACGTTCATAAGAATGTTTCTATCTATGATTTTTAAAAGTTAGCTCTTCACGGCCCGAGCGGTGAAGCCAAGGTCTCCGGTCCCCTTCAAAAGGAAGGGGATTACGATATGGTTGCCTTGGCAACACCGATTCCCGTGCTGCAGTATCAAAAAGATGTTGCAGCTTCTGAGGAAACTAAAGTCAATAGTAGTTAATAATTACTTGTACTTTAATTATTTCAATTTGAAACTTTCGAAGATGATACGAAAATCTAACAGGTACAATTTAAGCGACCTAAATCGTATCTCTTGTAACATGCAGTTTTGTAGCGAACAAGCTTATAATAAATTAATTTGTTATGGGTTAAGCGTGGTAACATAACAGATATTTGAAATATCGAGGTATAATTTCCAGCCTTTGTTTACAAATTAATATCAAATGGGAAATGTAATAAAAAATTAACTTAAGTGGGGACGCACTTGGCAATTCTCCCCTATATTTTGATGCTTTGCTATCTTTCAAATAAACAGAGAGTCTAATAATCCATCACATTATAAATTAGTATGTTGTGTAGTATACGTTGTTCAACATGGAACATTAATAACAATGCATTAATAATCAAAGAGTACGCAATTCTAAAGCCGACGTAGATTCACGATTACCCTAAAAAGCAGTACGCTGTATAACAATTACAAGCTCAATTTGGATTTTCGCGGTTTAACATGATTAAAATGCAATTGCGTAAGTGGATGAAATAGATATAATCGTTGAGTGACGCTTTCAGTGTTGCTCGAAAAATGCAAATCGCGGAACAGAACACGAGCGACGGTAACTCGGGCAGTATGTACGTGGTCCTGACAATAGaaaaaaaaaaaaaaaaaaaaaaCAGAGGACCGATAGATGTTCGTGATAGACACGCAAAACTGTAAAAAAATCTCCACGAGTGACGACGCTCGCGTGTAAACCTCAGTAACAATGTAAATTAATTCGTAGGTCACGTTTTCCAGAGTATGAATTATCGTGTCGCGTTGCTGCAAACTATAATTTAAAGCGGAACGCCTCTCGCTTTGTCGCCTCCATGCGCGTGACATCGTTATACTTCGCGCAAGAACAGTGGGTAGGTGGAAACGATTTATTTCACTCGGACAATAATTATAATTAAACGATGTCGACGAATAGCGCGGAAAAACACGGATCTACCGCCGAGGTTTAATTGCGCGGGAGAAGTCGGCCTCTAATCTCAACATGACGTATTTAAATTGTTACTTCGGCGCATAACCGTATAAAACGTGTTAACCGTAATCCATCAGTTTGATAACGTCGTCATGAAAGCGGATCTTGATAGATCACGTACATTTTTAATGCAGTTGTGAAAGAACTATTTTAATTTATACGTACGCATTCGGAGATTCCTAAATAATATGCGACATGCACGTGCAAAGAGATGAAATTTCGTAAATATTTATAAACATTATTTAAATAACCAGTTTTAAGGGAGTTTTATTAAACGTACGTTGAATAAAACATGAAATTGCAGATCTCATCCGTAAAATAAAAAGTGTTCTTATTTTATGAAAATAAGCAGTGCTTTATGCTCTTTTATTCTGAAGTACAGCAAACTTATACGAGATATCAGCATCTTTCTCGTGACTCATTTCGCGTCTCTTTTCTATTGCTTGAAGATTTTTGATAATGTTTCAAATTATCAAGCGCTCACGCACATTTACATTTAACCGTGCCGTCTCGCAAAGATCACTCATTCAAATGTTAATACTTCCGTAAAAACTTTTCTTCTCATTTGAACATTTAGAGAGTCTATCTAAAGATCGAGAACCTACAATCGCGCAAACGAGGGCAAACTTAATAAAAATGACGAGTAAGAAAAAATATACGAGTTTGCGTGTACTGCAAGCGCAGATGAAAGCTTGTTGTCGTTATTATCATTATTATTATTTACACGGGTTCCGAGTAAGATCTTTTTGTGCCACATTATTGTATTACAGAAAATTACGAGAAAATACGCGAATCATTACCATTTCCGCTTTGTTTTACGAAATAGTTCAAAACAGCTGGTTCgTTtCACAAAGaTATTtCTATCTCAAAGTTATATAGAGATAAAATAaTAAGAATAATATAAATATATTtCAGTTAATGAaGAAAaTaTATCAaTGTGTGTGTGTGTGTGTGTGTGTGTGtGTGTGTgTGTGTGTGTGTGTGTGTgTgTgTNNNNNNNNNNNNNNNNNNNNGCGTGCGTGCGTGCGtGCGTGCGTGCGTGCGTGCGTGCGTGCGTGCGTGCGTGCGTGCGTGCGTGTGTGTGTGTGTAGTTTTATTATTTTAGCGTTATTAGATGTCACGCAAAATTTAATAAACTTTTTTCTTGCGAAGCAATAACGTACTCATGGCATTTTTCAACATTTTGTCAAACTGATTCGGCATAGTAACTAAATTCAGGGAAATTAGAAAAATGGCTAAGAAGGGGGATAAAAAGAGAGCCGAGGAAATGAGAAAATCGTCTACAGAAACGGAATCCATAAAGAGATTGTGCCTCGAGCTTCTGAACTGTCTGCAACAGGTACGCTATTGTGGCTACGAACAGACACATTTTCCATTATCATAGCCATTCCCCTGTCCTTTCCAACCTCATTGTCTAATTACATATTCACGTGGTTTGCCACGTGCTTATAATTATGATTCATTTTTAATAATAAATGTCATTACGATATTTCTGAACAAATGTCACGGTATCAGACTACAAGTAGCAAAGTATTCGTACTCAATTACAATTTTATAAATTTTAATTTCAATTTATACTCGCGTAAAAAGTAATTCAATAATAATAATGTAATTCAGAATTAACATCGTTATCGTAAGCATGAAGCAACACGTGTAAATGAGCAGCATGTAGTCTATAATTATGCAACTTGCGCGTTACTCGTAATTAGACCACGGTTCTTGCAAGTTGCTGAGCACCAACGTGAATTTTAATTAGCTTTGTTGTTTTCGAGCGTTCTTTATATTCCTTTTTGCTTCATAAATGATACTCGAGTTCCGAGTATAATATTTATTTTATCGTAAAATTTTGTTTCAACTTGGAAATATAATATTTAGAAGTTTATTTATTAAATTTAATTAGATTTATTAATATCATACTTAAATCATATACTCATATTTGGGTATATTAATAAATTCAGGAAATAACAGGTTTATTTTAAAAAATTAAAATTAATTAGAATAACAAAGTACAATTCTTCCGAATATCCAGCAGAAAGAAACAACGCGAACAAAATCTGTGCACTGTGGAATGATGATAACTGATCATCATAACTGATCGATCACAACTGATCATAACTGATGGTTATTGATAATTACCATGGCGTGCGAGCGAAACCTTTAACTGAATTATTCCCGTCGCTATCCTGACGCAAACGAGATTCTCCTTAACCAGTTCGTCAGAGCATTAACAGATAATCCCGCTGCGCTCGAAAACTCGATGACGTTGATCAATTAAATGGTACGACGACGTCGCGTCTCTGTCGTATCTCGTTAAAGTTGCGTTTGTGCAAACGCAGGTTTGTACGTCGGTCAACGATAATTCGGAATGACAACCGATTCGTCAGACTGATATTCGATGACTGCCGAATTAAAAATCGCGACTGACTCGACCGCGAGACATCGACATGAGGTTTTAACTCGATTTACCTCAAATACGTGACGTTTTTGACTCTCTGTCAACTACGATGATTTCATTCGATGGTAGGCCCGCTGAATCGTTGATATTGTACATATGATTTCATTGTGGACCAGCACTAGTTTCCTCAAAATTCAAACAGTATTTACATCCACAAATCATATTTACTGTAAATGTAATGAATATGCATACTTAATATAAATTGTAATATTATAGATTTTCTATACAAATATATTGTGCATAGAAAATCTATAATATATTTTATATAATAATCTAAATAATTTtATGTAGAATTATCATTTTATATAAAAATTTATAAATAAATCTATATTAAGAGAGTTGTTGCTCAATTTGTATCGGTTGCTGAATTTGTATCACATCATTATGTTATGTTTTTACTTAACATTTAGCAATATTTGACAACAAAAATATGAAAAAAAAATAAGAAGTGAGTAATATCGACAAAAATACCACACATTACCTCTTATTCCACGAGTGCTAATAATTCTTTAAAAATTCAGGTATAATTGCTTAATTTTTGATTGATTTATATACATATCTGACAATAATGTAATCATGAAATTTTCATCTTTATTTTTTtGTATTTTTGTAAAAAAAaGGTTTGTCGTAGAATATTTTACATTTATTGTACATACACATTTGCAATTATTATAAAGTTTAAATCAATATTTAAAATCTTTCAAATTCCTTAAATCACACCACGCAAGAAATTTCGTTATAATAAACAATTGCAATGGTTCTGAGGATCAATGTACCGGGCAACGGATAACAACGATAAATACTGATGAAATCATTATATTAGAGTGAAATAATTATACATTTGTCTAAACGTTAAGATGCAACAAATCATTCCTGATTACACATATTCGCAATTTCCAACGTATACATTACATGAATCTAGCGTGGTAATCTGAGTACATTATAATGTCGTAGTGATTAGTAAATGAATAACAATGTGTATTATTGTTGTTATTTGAATGTACATATCTGTTATTCGCGCCCGCAGGGGGTATGTAGTTATAATTTCTTGGCACTTTCCACGCGTGTCTCATTGTATCATATTGTTGCATTGGACCACCAGGCTGCTGATTTGCATAATCTTGGTGTTGACAACGTGCATTATAAGCATTATGAAAAACAAATCTATTATTATTTCTAGAAATGTATTGCGCGTTGTTTCTATACATTTGATTATTATAAAATTGACCTCTACCTTGAAAATTTCTCAAGAAATATTGATTTCTCCATCCTTGTTTATGTCTCTGTTGATATTCTTCATTATAACTGAATCGCTGATTTTGAACTTGTGCTGTATTCTCTTTATACGTCTTTTTATTATTGTGTGAGTTATTTTTCTCTTTATCTTTTACGTTTTCTTCTTTATTTACCAGGTGCAAATCAAGATATTGCAATCTGGTAATAATCGCTTGCGCGTCATTAAAATCTGCGCCTACCAATGCTTCTCGCGCCCGCCGCGATAACTGTTTCGATATTTCGAAATTTATTTCGTAGTCCAACATTTTGGGCTCAAAATATCTCGCGATTCTCAGCTGTTTAGAAAAGAAAGTTTCTAAAGATTCACTTTTATCCTTAAATTGTCGCGCCAGCCATTTTTCTTTTATTCTTAACTGGATTGGAATTGAAAAGAATGCTTTCTTAAAGTGTTCCTTAAAGGAATCGAGTGTTTTTATTGTTGATTTACTATTTTCAAACCAATATTTCGCTTTATCCTCCAAGCTGTTTTCTATTATCAATAATTTTGCCGAGTCCGCTACATTTCTCGCTTTAAAATAATTATCTAAGTCATTTAAGTATTCGATCGGATGTTTTTTATCTTCGTCACTAAATTTCGGTACTTTTACGTCTAAATTGAATCGCTGCGCATCTACTAATAAGTTCGAAATAATTGCCGATCGGTTACCACTAAAATTATTCGCTTCGTCATGCGCGCTCTGATTTTGCCCCCTTCCCTGTTCATATTTCAACCGTAATGTTTGCAACTCGCGTTTCACTCTATTGAATTTTTCCTGCCGCGCACGAAATTCTCTAATTTCCTCATTTAGTCTTTTAACTTGCGCTAGCTGCTTTTCAATATCCCTTAATTCTTCCTCCATGCCTTTATTTTTATCAAGTGACTTTCCACTATTTTCTCCTTATTTTCCTTATCTGTACCTTCCGCCAATCGTTTTACCAGTCCTCGTCAACGTTCACGCGAGTGCCTCTCTATTAAAGGGTGTGCCTATTATTCTGTGCCCAATACGCATATCTCTATCCGTTATTCTCTTCCATATTTACTTTACGTACATGTGTATACTTTTTCTCTTTCTTTCCGTTCGAGCGCCGAATGTAACGGTTCTAAGGCTCAATGTATCGAACAACGGATAACAGCAATGATTACTGATGAAATCATTATATTCGAGAGAAATAATTATAAATTTGTCTAAACGTTAAGATGCAACGATTGAGTCAACGTATGTTAAATGAATTCGGCGTGGCAATCTGAGTATATTATAATGTAATGATTAGTAAATGAATAACGATGTGACCTGAGAGAGACAGAGAAAGAGAGAAATATGGAGGAAAGGCTTTCGCATCGCCAATGGGCCGGCTGTGTTTTTCGAGATGAGGGGTCTCAATTGGGTCGTACTCCGTTTCCTCGTGTATAAGTTTTTCCAACGTGTGCTTCGGAGATTTTCTCTCTTATGACAACGGCACGTCTGGAACACCTACGCGGGGTGCAGCCTGGCGTCCCTAGTTCACGTCTCGTCTTAGGCTGATGGCAGAAAACGAGACGTAAGCGCTTAAGTCTGACGACAGTCTAATAATATTTAGTTGTAACCTATTAAGGTATATAATATATTATTAGTACTCACCTCGTCTCTCCGATGCACTTATTAGATGAAACATCCAACACAACATTTCTTACGTCTCCACGTTTTTTCTGTCTTACCTTACGTCACCTCACATTAGACTTAAGCGCTTACGTCTCATTCTCTGCCATCAGCCTTATCAAAATTCAAACTTAACATGTATGTGCTTAGTCAACCAGTTGAGAGCGTTCTAGTTCTTCGCCAGACTCAACGAACCTTCTCTACCAATCTAATTCCTCTCGACCAATATAAAACTCATTCCCTcTCCGAATTCTTTCTCTcTTtCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNttCTCTCTCTcTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCATCATTCGAATATCGCCATACAATATAAATGTAAGACTGATAAGAGATAATACTAAAACTGATAAGAGATATGAATATAAATAGGTCATTTGTAAAAATAAGTTTAAGCCAGTTTTATTTTGACGTCCTTATCTTTCCATTGCTATTCATTAATTATTAAATATTTGATCCTTTTCTGGTAAATCATTAATAAAATAAATTCTTTATATTTTtAATTATTTTAATTACCAAACTCGCTACTTTCAAAAGCGATATGATTTTGATAACCGCTTGCAAAACAGCTTTATTTAATTAATTTGTTATTGACAAAAAATTAAACATTGTAGTACTAGGTACCTGAAATATCATGCTACAATTTCCAATATTTGTTTGCGTACCAAATGAATAAGAAATATAATAAAAAGTAACTTGAATAGTATTTCATATAGAAAATTTATAATATTACAATTTACAATATAGTAACGAAAATAATATCAAGAGACATTTTTTTATTTTCTACAACTTCCATATTCTTTATTTCTTTTATTCGTCCTTTATCAAAATATAAGAAAGTTACACAGAAAACAGCTACGTCTCTATTCGTAATCGTTGAAATTTATCAACAGCATTTGCGTCGAATGTTCCCCTCGATTCGAGTGTACGAAAGGGCGGCAGAATTACGTGCGGCAGCCGCAGGATTAATTCGTACACATCAGAATGAAATTACGTGCGCGGCTAGTACGATAACACTTAATTAAGTGGTTCTCCTCGCGCGCGAGTTTCGGATTTCTCACGCTAATACACACGGGGACAATACCATTGCTGGCAGCGTGCAAGAATGGCACACGGTCGACAATGGAGGCTTAGGTACGCAGAAAGCGAAGATGTTGGCTGCGCACGCAATATGCATAGCATGAGAAACGCCATAGAGGCTCGTTCTATACAACGCCCGTGTGTTCGTTGGTTGTATATCAAACTATACCTCTCCGATGTCTCGACCACCCTTTTCACAGCCCACATCGCATCCTTGGAGAAAATCCTTATACTACGCCTACGTTGTTTGGTGACACAGCCTTGATAGCTCCGTCGAAGATAAAAGTGGAGATGTGGAGAGAAAGAAGCTATTTTTCCACAATTATTGGAGTCGGAAATCACAATGAAAAAAGGTCGAAAATTCAAACGAGGATCGGGCTATTTATAAATTGATTCCTAAAAAGTATTAAAAAATGTTTGAAATAGTGCTTGCAATGGATTTCAATTATTTTTAATGGTAGTAGTTCAATCTCATTCGAGTCTGTCGATAATAAACAATAAATATTAACGTTCACGACGGCACGGCCATCATGCGGGTCATCGTTATCCCACCCACCTGTACTACCGATCAGTCAAGCACTTTCTACGCAGGGGATGGCGATATGTTTGTATACCTGAAGTATGCATGCTACCCTATGTGCATTAGTCATGATCTGACCGCTAATGGCCACCTGACTCGTGATCCATGCGGTGATCACACTGTTCGCAAGATACACTTACCCGAAAACGTCATGATTGTGTTTAGATAGTTTTGAAGATTAGTTACAACTGACCTTACACTGGTCTCCCCATATGGTTTACATAGGTCTAGACGTAGACTATAAATTAAAAAAAAaTTTTAAACACGTTTTTCAAAATAATATCTTCAGATTGGATAGCAATACTTGAGCATCGATAAATCTATTGGCAAAATAAATATTCTTCATACATCCTGATTTCAACTTACAAAATTCATAAGAAAACATCGTAAATAGCGAATGCTGTAAACTTACTTTTACGATGTAAACGTGGGAAATAGCGAAATGCTGTTGCAGACGTCGATTTGCCGCGCGTAAAAAATGCGAAAAGTTAATCTGGCATTTTTTTATCGCCGCCATGCAGCGCCAAAATTGAGAATATGCTATTACATTATATATTATTATCGGCAAATCTCGTTTTTATCTTCTTCCCTTCACCCTTCCCTTTGCTTACTATCATAGTTATATAGCTTTCCTTGTTGAAATATCAATAAAAGGTTATATTGTATTTATTATTTGCACAAATAGTGCGAAACTTGCAATCTGTTATCTCTTATATATTTTCTCGGCATAAACACGATCGATTCGTTATTCAGTCGAGTACAGTACGACTGCGCGATATTTTCTGCAATTCCGTGACTACATTAATTTGTGTGTCAATTCCAACAAACTCGATTTCCGCCGGGGATGGAAAACTAACTCGCAAATATGCTCGAGAAATGAATTTCAAATTTATATTTATAGTATTTCTATGGATATTGCAATTAGAGTTTAAACCGTGATCTTTAGTCATATTTTGGTTTTTGGAATACTTGTCAATCTTTCTGTTTTCTTAAAAGTTCTTTTTTCAATAAAAATAAATGTAAAATCAATTCTATAAATATTTTGATCGTGTCAAGTTGTCCAATTGATGCAAAGACAAATTGAAAAAAGTGTTTGATATTTGTGACTATATAATTGCGTGGTAAAATAATTTTTGGAAGTTCCATTTTGAAAATTATGACTACTTTAATAACCTTATACGTTTATCAACTATAAAAAGTTTTATTATAAATTACAATAATTCCGAATATTAAATATAGTAAGATATTAAGATATGAATGATAAAAATAAAATAAATATTTCCATGTAGTAAATGTAATTATAATTATAGTAAAAATAACTATTTTTTAAACATTCGCTTATTATTCATATTCTATGGTAATAACAACTAAGCTATAACCATTGCATGGTTAAAATAACTATTATAGTTGGCACTAAAAATAGCTGTATATTATAGTTAGTGCAACCAATTGTTTTtTTTTTtCTTTCAGTGCATCTAAATCCGAATAATGTATAATGCATAAGATCAAACAAAGGTAAAACAGGATTTCAATGTTCCTGGCCGTTTCCTTTCAAGCAATTTCCTAAGCTTTTGCGGACACGTCACGCAAGTTCTCATCCACTTAGAGTTTGTAGAATTTGCGGTTGTCCGTGATAAGGGGATTGTCTGTCGAATCCGCATGGTTAATCGTGATGCGAGGGTTTATCCAGATGTTACGAAATCCTTAGAGCCGATAGTTTGAAATTGGCTTGGTCATGTTGAATTGTGTTTCAGTGCGCTTAATCGCTGAATTCAGCGAAACATGGCATTGAAATAGCTCTGTCAGCGTAAATGAATTTAAAAGAGGACACATGTAATGTCCCGCTACATATAATACAATTAAAGATTGTAAATTCTCACGTGTATAATCTATGGACTGTACATTTAATCCACTAGAATTTTTCTGAAAGATGATGTGAAAAATTGATACATTTACCAGTGTGACACTTTTTCAAATTTGTAAGACTATAATTGATATAAAAGTGTCAAGAAGGAATTTTGTTTTTGTTTGTGCAATGATATTGCAAAGACTAAAATAACAAATTATCTCACAACATTATTTATGATTGCCAGTGATAAAAATAATAAATAATTTCTTTGGTCGACAAACTGGCAAGTGTTTATTGAAATTTCTTTACCTTAAAGTCATTTTGTCAACCAAATTTGGAATTATTTATTAAAAAGTTTAAGTCTATTAAGATCATTAAATGATACTGATGTCTTTATGGCTGATAGTAAACATTCTATTTGATTCGTTTAAAAATAATTAAATTTCCTAAATTATTATTTTTTATCGGCTTTTTTCATAAAGGTAAAAATAACGACGATTGCAATAAATCGCAAAGCTAAATTACGAGTGCTCGCATGCGCATTAGGTACGCTAACAACGTGACATTGTTACCCCAACAATCGGCGCAATTGCCGCTCGCGTTTACAGCAAGCGTGGGCGTTAATTATTTTCCTAGACCCGACGTTGTAGCTTCAGCTACATTCGCGAATACGTGTAAATTCTGCTGTGGGGTAGAGGGAAACGTTGGGGGGgAAGCTGCGCGTGTTAGTTACGCCGCTGCACAAAACGTAAACTGCGTTTCGCTTCGGAAAGGTGCCGGGCGTGCCACACGTGCGCAACCCGGATCGTTCTCTCGTCTCTCGATGACGCAAATCCTGACTCACAGAGACGAGAGATACCTCCCACGGAAATTATGGCGTTGTATTGCTTCCCGAGGGTGGTGGGTGCATTACGTTCTTAGCCAATGTCCCTTTGTTGCAGCGCGTGGATTTGGCATGAGGGTGGTAGGCGGCAAGACCGGGTCGGACGGCCGCACCTTCGCGTGCATCGTGTGGACCGTGCCGGGTGGCCCCGCCGAGAAAGCTGGCTTGCAACAAGGCGACAAGGTACGTTAATGTGTACTATATATACCCTACATTTTCTAAGAATCATAACAAGATTACCTTACACGTATAAATTCTCAAACTAATCTCGAAGTTGCCTGTCGTGTCGTGAGATCTTTAACTTTCTTTCCGTTCCGGAGAAGCTTTACAGAAATGTTGGATATTTGTTCAGCCACTTGTTTATTATCGTATTTATTTTTCGAGCGCTAAATATTTTGGAGTCACGCATCCCCTATTTATTCCAAGTATCATTAAAATATATTTATATATGTATATCACGTTGCTTTTATATAAAAACATATTTGGAATGAGATTTATTTGTTCACTGGAAAAAAGTCTGGTTATAACCAAATGTATAGTAAAATAATATTAATTAAATATTTTGTTAATATAACCAAAAATAATTTtACTTTtCTAAATATATTTAGTAAGTATTATCAAATCTGGTATAGGCTATTAAATATTTAGAAAaGTAAAATTATTTTTtGTTACATTGATCAAATATTTAATTGATACTATTTCACTATACATTTGATGGTTATTACCAATCTTTTTTTTCAGTGTTTATTATTATATTTTAAATCAGATTATCTATCATTATCATTGTTACAGAAAAGTTAAACTTTACTTCGAATAATGTATTGGTATTTCGATCGATCCGATATCTGTTCGTAGCGAAGATTACAGTATTACTTTATTGCTTTGTTCAAAACTATCCGTTTTTACAGATACAATACAATAACACATCGCCTCTAACACTTCGTGAATTTTATCAGCTCAAGGCAACGTTATTAAATAATATAACGTAACGTAAACGCCCGAGAAAATACTATACAGAATAAAGTACGGATATAGAAAATATTTTCCCACGAGATGTTTATCGTTACCCATCGGGTATTATGAACGATAAATGCGTGTAAACATCGACATCCCTCGATGCATCAATTTTAATTGAATTTAAAGTTGAAGTACTGACAGTTAAGTGAAGAGTCGTTCTACTCACTCGCATGTCCGTACTAACATTCAAATTGATAAATTTCGTTTAATAAACTGCATATCACTGAGAAGCACATTGTGCATTAATTTGTAATCAGTTTCGTTAAAATGTGTTCATGTAACATAGAAATGTTGCCAATACCGATTACATAGCTCTTTTAAAGCGACACCCCTGCAAAATTCGATCAAATGTCATAACATTATTAGATGTAAAAATTGCTATGACCATCTTATGGAAGATATAATAATTATAATACTTTCTAGTTTGTATTTGTATTTCCAAAGATTTTATTTTTAGTTTTTGTGTAAGAAAATAAAATTCAAAAACAAAGTCAGTATTGATGACTTCTTTTAACGTATTCTAAATACTTTAATTATTAATGATATTATTAAATTAACTAGCAAATTTTTTTtAATGTTATGTTTTTTtGGTTTAATTTAAAAACTGTACTTCAAGCCTTCAGAATATGCAGCGTAAAATTCAGGAAACTATTCTAATAAAAATATCATGAAATTCAATTTTTCTATTTTTAAGTTACACAAGTATATTAAATTTAGGGTATCTATTATTGGAAGGTATGCGCATAAAATTTAGTGCACTTTTGACAACATTAAATATTTTTAATGTACCTGTTTAAAATCTGCTTCCGTTACGTAACATTAAATTTTGCTAACGTATTTTAATAGTGAAAAATGTATATAAAATTACCTAGGAAATTATTGTTTAAGCACCAATATTCGCTTTAACCATTATAGGCCATTTCTTAATTTTAATTATGTCACACACGTCTTGTAATTAATTATTAAACATTCCCTTATAAAAAAAGTACACCTAACTAGACGATGGTCCAAAATGACACTCAAATCGAGTGTTAATCCCCAAGTTGGAAGTTTATTTGGGAGTTAGCCTAATTGGATGTATCTATTTATAAGAAATCACGTCTATCCTTACGTTCAAACAATGCAAAATTTAAAGCAAAATGATCTTAGACAATATTTGAAATTATTTGAATACCATAATAGTCAAATGTCATTCAAACGTCAAGCCGCGCAAAAAGGCGGAAAGTGCAGTCCTTTGGACCCTCTATCTGCCCCTCGAGTGTCATCGCGCATAAAGGGTCGGCATAGATAGATAAGCACGAGTGATTGATCGATCGCGGGGCGACAAAAAGACGCTCTCTCGTTTCTGTTTACCATCATTACATTTTCATAAAGATTCCCCAACGATGATCGCTTATCGTCGATAGACTTTTCTCTCGCGCTCAGCAGCAACGTATAATAAGAAACGTGCAGATGTCGCATAACGCCTCCTCCCCCCGTTCTCGTTATCGCATTATTCCCCCCAAAAAGAGTAAAACTTTCTAATGCACGATGAAAAGCGCAGGCAATGGCAGCAAGGAATAAGGAACAATATGTTAAATAAGGGAAACATATAAAGCGTTCATTGTTGAACACGTTGAATTGCTTATTCACTGTCCGCTATTCTCTATTCCGTTCATTGTATCTAGAGCTTAAGAGGGCACGCGTTCATTCTACTTTCCTTTTATCAGCGGGATGAATATCGAACGGGAATTGAGATAGCCGGGCGACCCTGGCCTACCGCGATGCGAAAAACGAAAAATGCGAAGCACATCGTGAGCACAAGCGTAACGTATATTTGTTAGTTAACTCCGGCAGAACGAAAATCCTCGATACGACGCCTTCGCCTGTCCCGCGGATTCAGAAATGTTTTGTTTAATCCGCTTACATCCCGTCCCTCTTTGTAAAATCGGAGCAAACTCTCTCTCTCTCTCTCTCTCTCGACGAAATCCGTGACGAGCAATTCGTTAGTGTCGAGTTCTGACATAGACAGGCGTAATACTAGAATCATACATAATTTCCACGATTATGCCCCGTCCGTTTCCGCTGTTATGTGTCCTGACCATGTGATGATCAAGTTTCCTCATTTAGAATGACAATTGTCATGTGCTTAGAAATGATCTTGTCAATATTCCGTGCTTATCCGGTCCAGTTATTGCCGTTGTTACTACAAATGCGACGTTATCGTCCAATAGTAATTATTATTTTGTGTAATAATCGAGCAAGTGCCTAAATCTTTTATAACAGAACACTAAGAGACAAAATTGTAGTGGTAGCAACTATAAGGGAACAACCATACCAATTTCATTAATATAATTATGATATATTAAGTAAACTATATTATAGTTATCGCAACTAAGTTAATGGTTAAGAGAACTAATAAAAAATAGTTGTAATGTACTATATAATATAGTAATTTCAACTATTTTTTTATTTCTCTTAACCATTAACTTAGTTGCAATAACTATAATATAGTTCACTTAACTATATTATAATTCTATTAACAAAATATGTATGGTTGTCCTCTTATAGTTGTCACCACTACAATTTTTTCTCTCAATGTATAAATAAATAATCAAAACTGAAGCATGTCTTATTTTACATCGTCATTTTCGCAAGAGGAGGAAAAGTATTATTAAATAACATATAACCCGCTCTCGTCATTCCGCTTGCAGAAAGATATATTGTACAAATACAATATACGTATAAAGATGTGATTTATGAAAGTCATTTCCTGTGGTAATCGGCGAAAACGGAGTTGCGATATGAAACCTTTTGCGAAAATCTGACCTTCCCTTGCTCGATGTGTGCGATATAATCAGCAATCTAGATTACTTCGCTCCCCAAGTACCTATTTGTCGTCACGCGTGCAAACCTATATTTAGCAGCGCGTTTACAACAGAAAACGGATAAGTTACCGATTTGACGATAGAACAGAAGTACTCGATTTACTGAAACGAAGAGAAAAAGCACCGACGTGGGAAATCTTTTTTTCTAACTTGCGAGAGCTTTATCGAACGATCCCGGTCCGAGAGAATAGAATTTTGTGGAATTCAAGAAGGACGAGCATCTGTCGCAAACATACATGCGCACACACACACACACACACAGACATGTATACCTATAGAGTGTCATGGTTTAAAGTTATCTTTTCTCTCTCGATGCTTCAAGTCACCCCTCGTTCTTTTCCCCACGATCTCGTTAAATCCCAAGAATAATTAAACTTCTTCCCTTCTAAGCGAGAGCAAGAGAGAGACCTCTCTCGAAGATCAATTGCCGAGATCGCGTTTCGATACGACCAAATTCCAGGCAAGTTTATCGCCAGCGAGATTAGATTATACTTCGATTGCCACTCACAAAATTTCTTCAAAAGTCTCAACAATGTTTCGTGACTAGTGTCCCGATTTCATGGGCAAGAATACGAATAAGTTCAGCAATTTAAATGTGTAATGTTTTTCTCATTAAATTCCGATTCAATAAATTAAGTTAAAAAAAaTATAGTATCTCGAAATTTTTAAAAGTTATTTTGATTATTTTTGAATTACGACGATGATTTATCTTTATAACTTGAATCTTAGAAAAGTTAATTATTTTTAAAAGTTATTTATTTTAACGTTTTTAACTTTTTAAACGTTTATTATAAATAAATTTAATTAAAAaTATTAAATAAATAATTTATTTCTATAATAATATAGTTATTAAATAAATAAATACGTAGGATAATCAAAATATGAGCTCTTTAACATCTTTTACAGTAATTTGTTATTCAAATAATTGATTTTGTACAACACATTTAGTATAAATATAAAAGAGCAGATTCATTCATTTTATATTTATTTTGAACAGACAAACGTATTTCGTGCTTTAATATTATTCTAGTTAGACACATTAAATAACAGCTAGCAAAAAAGAGAAGAAAGACAAAGAAAAGGGAGATAAAAAAGCATTCTTCTCGCGGAAGTGCGAAGTAATTAGAAGCCCCGCGAGAGCAAAGTTCCTACTAAATCGGACCTGGAAACGCGGGGAACGAGAACGTAATTAAATATTGATCTTCCATTTTGTATCGCGCCGGGCAAAAAAAAaTCGTAAACGGTTTTACATTTCACACGTTTCGAATTTAAAACGAATGTTGATCTTTCATCAATTGTTTGCAATAAAAAGGATCGTGTCGAAGTTAAAGAATCCATCATAAAGTATGATGGAACGAAAATAAAATCCAGATTAAGCTATTATCGACGAATTGAGATTCTCATGCTGGATTAAACGTTTGTATATTATTTTCCCGGGACAGAAAGTAAGGTCAAAATTGAGATTTGAAAATTTTCTTTCCCCGATCTGCATTATACAGGGTGTTAAAAAAAAaCCATTCAGCATTTATATGGCAGATAGTAAACGCGATACTGACGAGTAGAAAAACCCTAGTAAACGTAGGTTGAAAGCTCAACCGTTTCTCAGATATAAACATTTTTTACGTCGAGCAACAAAAGTATTTCCACTAGCACGATCATATAAAAAGTGCATATCTACCATTTCTTGATTAGAGTAACACGCCGACATTTTAGCATAATATCTTATAACTATGTAATCAACAAATAATGTGTAGATCACTGTGGTCGATGCCAATTAATTGCTAATAAATCTTCTGTTATGAAGTACACATGGAAAATGAATGAAGACAAAAAGGGACGTGCTGAATGGTTTCTTTTGAACACCCTATAGATAAAGCCCTTACTGTCCTTATTTGTGCTATGTTGGCGTGATGTATCTATCAGTGCGGTGGATTACGACGGAGTATTGCGTACATATACTCGCGGTTAATGGACGATCGCCCACGCGGTAATTAATAACAATAAAGTTTGACGTCGAGTCGATCGAACAGCAAATCCAACTCCCAGCATCTCGCCTTCTAGCAACGTTTGCTCCTGACGTCACATGAACGTCGTAGTCGCGCCGGTTTACGTCGGAAATGAAATTTAACGTCAACGAGAACGTAGTACGGTGTTAACCGGCGTGATGTGATTCGATAAATCGTATAAGGAACTTTTAGTGCTGACTGATACTTACGCAGTTTGCGCGACACGCGCGTGTTTCATTTATAAATTACTCTTCGAATGCCGAATACGAATGAGAACGAACATAAAGATGCAGAGTAAAAATATACAGAAGAGCAATTTCTAATATATATTTGAACAGATTACGATCGTCGAAATCCGTTTGACAGCAAATGAAATATTTGTGAAATACGTCGATCGTAAAGAGGGTTGCCATAGAAAATAAATTTTTAAATTTTCTGACTTCATGACTTTTCAGACGACAATGCAGAATTTCTCATGACCAATATAATTTTAAAAGAGCTTATACATAGACTAATGAATACAAATATACAATTAACTTTGTATATTTTTATAAGAAATCGGAAAGAAACAGTAAACTCATATTTATTCTATTGTAAAGATTATATTTTTCTCTAATCGACACTTAAATTCTATTAAAAAaAAaGAAAAAAAaTTAGTGTACAATTCTAACACGTAAAAAATAATTTGTAAAGTTCGCGAGTTTACCTATTTGACTATAAAGAAATGTTTGATGTAACATTAAAAGAATTATAAGTACATATTCTTTAGAATAAGAGCATTTAAGGAAAGTGTGAACAAAGCTCAAGTTCCAGACTTTTTTTtATATCTTTGCCCGACTTTTCTGGCTCCTCTCTGACCAATTTAAATTTTCATAACCTTTCCCGTTTTCCAGGTCTGTGGGGACCCTGCATATATGTCACTAAATGAACAAATATTGTAATATACATACAATGTATAGTCATATACGTAGCACAACTAATTTAATATACCCAGCACTTATTTAAAATAGAAGCAAAAAAAATTTCATATTTGACTCTGCAAATTGAACATTGCAAGTTATATAAAAACATAACCCAGAAATTGAATCTAACAATAGCTTAAATTAAATTCGAAATATTTAATGCAAGTTGAATATTTATCTTGGAAGATTGAGATTGGAAAAAGAGATTTCAATGTGTCAATAGGATTAAAATAACTGTACAGATATAAAACAGAATAACGCCATATGATTTTCACATCATGCGCTATATTGTTTTAATATTTCATGAATGAATTTTGTGATGATTTCACGAGTAGGACAAATGCTGTTAATTTATTGAAAAAaTATTATATATCTTTTTCATTTTAATTTTATTTCAATTTGATAATAAAAAGTAAGCCCGGACAATCAACGTTATCGTTTAAAAATAAATTTCAACATAAGATAAAATTGCCGAAAGTACTTTCAAAAGTGTTTTCATATAAACTGTGTTCAGATATTTTGAAAACTGAAAGATTCTATTGTTAACAATTAAATAAATTTTATAGCAAGTATAATTTACAATAAATAAAATCTAGCGAGATAAAAGCATTATCTTCACTCTGTCCTACGTTTTTCAATTTGTTATTTTGAATGAATATTTATTAAACAAATATTTATGTTATAATATTTATAATATTTACGCGATGCCAATAAATAATTTGCATAAATATGAATGAAAAaTATAAAAAAaTTTAACAATGGATGGTGTAAAGAAACACGGTCAATTCACCGCAAAGAAAAAaTACGAAAAAaTTATTTACAGCGTATGCAATGCCTCTATTGCAACTTAATATAATGAATAAaTAAAaTAAAaTATTGTGAATGAATATTCTGATGCACGCAAGTTTCGTAAATATACGTTTTtGAACAATTTTCATGTTATTTTAATAAAGATATCTCTTATACGTATCTATCTTATAATATATACATCGTATATAGTATATATTATATTTTAATCGGCTAATCAAATATTTTATTAACTTTCTATTAAATAATTAAAATATAATTAAAAAGTTATAATTCTCAAATAAATCACAAAaCTAAAAAAaCTTAAGAACATGTAATTTTATCTAGAGTATTCCTTTCCAAAATATCGCTGCTGAATTATGTCTGCTGCGTACATATCGCGACTCATTAATAGTAGTGCTTTTCCGTTGAAAACGTTGGTGCCGTAATTTCTGAAATTTTATTTTTCGCCAATCCGTTGACAAAATTTTCACGCCTCTCATATATTCATTCATTATATCTGTCGCGTCGCGATATTTCTTTCACCACGTGAATATTCTATACATGAGGTAGACCCACATTAATCTCACGTTTCACGCTTTATCTCTGTGTCGCTCAAACACGGTTTGTAGAAGCGGCTGTGAGACAAGTATCTTCCACTTGTTTTACAGCTGCTTATACATGTTTTAAAATCTATGTTTTAAAAAAaGAAATTAATTCTAGTAATCATCATTAAAGATTGTATTAACCTTGATTTGATGTATTCTACACCCACAGAAAAGATTTCTGTATTTAATGTTCTCTCACTCTTCCAAATAGCATAAAATAAAATATAAATACAATCTTAATTGTTAGTGGAAATATTTTATTCTTAAATGGAAAAATTCTTAAATCTAATACAAAATAATCTTGGCAGTCTCATTAACTTTTTCAGACAGATTTAGTCAATGGAAATTTGTGCCGAATTTCATAAAAGTTTTGATTTAACAATAGATTAATCTGAATAAAAATTTGAAAaAAAaTTTGTAAAAAAATATCAGGAAAGCCGATAAAGGAGTTCCGCTTCGTAAATATTAACAAAAAAATACCTTGTCGCGTAAATCGTGAAAAGCCCATAAAGACTCGTTTTATGAGTAAGCAAACGCTGCTGGATTTTTCGTTAATTATTATATAATATATCGTATACGAATCTTTATTACAAAAGCTTGTTCACCTCTATTGATGAGTAGCGATTAATCATTATACGTGCGTCCGAACTGCGTAGCGATTAATCATTATACGTTATAATCGAACACATTTTTATTTTAAATGTAAGAATATGTAGGTTGAAATTTATGTGTTACTCTTGTCTCGAGATAATAAAAATCGCTCTTATTTAATTTAATGGAAGTAAATGGAAACTATAAATCTCATCTTAAGATTATTTTTATATTACATAAAGTTTTAATAAGATTAAGTGTGACAAAAATACTTTTAATCTTTTTTTTATTAGGTTACTAAAAATCTTTTCTAAAAGGgTAATAATTATATCTTATTAAAAATTATATATTCATTATTAAAAATTATAATTTCAATTTTAACGGACAACAAATTTTTTTAATTTGTAAATAAAATAAAAAaCATGATAAAATCTATTATAAATTTTATTATTACATTACTACTACGACTACGAAAAAGATTAACTCAGATCGAAGTGATTCTGCAATGCAGAAGCATAAAACAGATTCGAAATCGATCATTTTATAATTCTTGTGATAAATATCGCCGATCCTGCATTCTGAAAACCGCAATTCGGCAGCTTTCGATCGCACCGATAGATCGTCGTTTAAATCACACGACGTTTTTTTCTCTAGTTAGCTTCGCGGCACTGTGTCGCCGCCAATGTTCTATGAATATTCCTCAGTGTGTCCCGCGCTGACGAACGCATATTGGATTTTTTTTtGGCGGATCGATGCAATATATCATACAATGAACGAGGATCACGGAAATAGCGAACCGACGGCTGATCGTTTTCATACGCGTCATTTCCTGTATCCAGTTACCGCATCCACTATCTTCTCTTTATAAGGGTTCAAGGCAGTGAGGGAAAAAAAaCCGTTCACGTGGATACACAATGTGAACGCTGAAAAGCTCGTTTTGAAGCACCAAGACAGAAAATTGTGCGCGTGTGTAATAATGTGGAATACGTACGTGAGCAGCATGATTGCGAATTGAAACGAGTTTGATTATCAAAACGTGAAGAATGATTCGAAAAAACAAGAGATAAGGCCAAAGGGATAACAAATACGAAGAGACTTTAGTTTACTTAAAGGAATTACGTATATATATTAAATGTGAAATATTATTAATTTTGCAGCTACAAAATTCAAAGATATGTTAAGAATAAAAATTTATGATAAATAGATGAGGAGAGAGCAGCTGTAAAGTGCGAAATAAATGAAAAATACATTAAAGGGATAGAATTCTCCGTTGAAATATAAGCAGAGTGTATACGAGTATATAGATATAGCGCTTGGAGATCCTTTCGAGCTAAGGAGCAAAAAAGGTTTTTTTCTCCACTTTTTTTAAAACACAGAAAGTTGATCAAATGAAAAATTCTGCATTGCTATACCACCTGCGTGGAGTCATATCTCTCCTTCGCCTCCTCTATCCTGCGAGTCTTCTTTAACGCACCCGGGAATATGCAAAGGCAAAAAGATTCGCGCACAAAAGCTATCCGGCAATATTTGGAAAGTTGGAAACACCTTTCCACCTGCTTGGATAAATATTTCCATTTCGATGCAAAGTTTCTCATCGCAGGCATTTCTTAGTCCGAAAAAGGAAGACATCGCTTTACTCAGAGCGCACGGATCGCGAGCATCGCGATATAATTATGGCGTTGCGTTTGAATTTCATCGGATATCTCGCAGAGAATTACGCATTTCTCCCCGAATTTCTTGCATTCTAAACTGCTCTTATAAATTCTTTTCGTTAGAGGACTGCGAATCCTTCGCGAGTATTCGCCGGTACGTAAATAAATGAACGGCAGATGGAAAATTCATTTCCGAGCTATGAGCTTTCGAATATGAGTCACGCTGCCTACATCGCAACGACGATAAATGTTCTGTCGGTGAAGGAAAATTGTGCGCCGGCTTGTTGTACCGAGGCGAACTTGTCGTGAGAATGCATGAGGGGTGCTTTCGCGACACGCGCATGCATAGAATTGTACATACGGGCCAACTCGCGCGCATCCGAGATACATATTTCTATGTACTGCGAAAAGAGGACGTGAGTAATCGACTATTCCGTCGCGCGATACGCGTTTGATATCTTTCAGCACCTTAAGCGGCAATGAAACAGTTATCTGAGACGTTGTAACTCATGTTCCTTCGCAGGTTCTTTTATGTATACACGGAAAGAACAATTTTACTGCAGGATCTAAAAATTGAGCTAGATATACGGATCAGAAAATAAATTTATGCCGTGCCATCAAAATAAAATATATGTAGAACGCTCAAACATGATAACGTTATTCCAAACAGTTTTCATATTTCTAGCGATCAAGTTAAACATTTGATACAATTATTTTCAATAGTTGAATTACTTTCAGATCTGTATTTCAGTGAAGTTCTTTCCGCGCGGTAAAACATTAGGCCTGTTCTTTTTGGACGAGCGGTTCACCTTTAATCTTTTTCCTTTCACGTTGGGGAAAAAGAGAGAAAAGACGAACCGCACGGAAAGTTCGGCCAAAAAGAACAGACACGTAAAAAGCGTTCGCAACAGAGTATCGCGGATACGAGTATTGGCAGTTATTCAAATGTCAAATCGCGAAATTTACGAAGTCGCTTCACAAAATTGCAAACACTCAAAATATAACGTTGCCTAGCTTCAGTCCATTTTAATGTGATAGATCGATTCCGTTCGTAATTCCATCTTTCGCATTCACGCTCTTACACTCGAGAGAAAAATGGTCGCGGTGTATCGATCGCGCGCACTTTCTTCTTCCCCGACGTACAGCGATTTGCATTCAATTCCGCTCCGCAGTTTAATTGAAAGCCGTCAGGCGCCGTAATTAACGCTTGGTATCATGTTCCTCAAAGGATCGGGTATGGGCATTATTGCAAAAGGTTGGGTATGGGCATTATTATACGGTAGAAGTTGGCGACGCGAATATATTTTCAAATTTCACGCGCGCCCCAAAAATATGTAATAATCGAAACAAACGTGCGACGAGCGAAATTTCGTAAATTTCACGATTTGATATTTGAATAACTGCCGACACTGGTATCCGCGTAACTTTGTTGCGAGTACGTTTTTATTATTTAAAAAAAACCGCGAAAGTGCATGAATATTACTTTTTTCCTGCGTTTTTCCGTGAATTTTTCACATCGTACAGAAATAATTATGATATCCTAATCAGATGTTTAATTTGATTCTCGTTAATTAGCACATGACACTTTAACAAGTGTAAAATAAACTGAAATGTTATTCTACTCTGTGCATATTGCAGAATAGGAAGTATAACGTGTGAATACAAAAAAAAGGTGGAAAGGTCACTTAAGTTATTTTTTtATATTTCGCATTTGGTGCTGTTTTAGATGCAAATCAAAATTCAAAATGGTAGCTTGATGTTTTAGGCATCTATTATTACAAACCATTTAGTAATAACAAATTAATTTGTTACAATTTTTCTACCATATACTGCGAAAAGTGTGATTTAGAAAACCGGTTACCTAAAGTATACTTGTGGTCTTTTAAATTGTATTATCTTCGAAAATATTGAATTTATGAATTAAAGTTATTAAAACTATAAAAATATCATTATTTCTTATTTCATCATTATTATATATCAAATATTCAATAATTATTAAATAACAACATTACAAATTTAAAAACACCAAAATAAAACTAACTTGAATTTATTTTTGTAACTGACACATTCTTATTCATAACAAATACTAGTTTTACTGTTATTACTTATCTTACGTAATATTATTTTTTtAGTAAAAATTTGTAATAGTATATACGAATTAGGAAACTTGATAGAGATTATGAAGATACGGATTTAATTTTTATAGTATCTGTAAGTATGTGTATATATAATGAATGTAAAATACTCTACAAGTCTTCTTTTCTGAAAATAGAATAATTTAAAATAAAATTGCATAATTACATTATTATCAGCTATATACGTATAAATTGATAAAAGATTTACATCAAATGCATCTGATTTTCTAAAATGCTGGTAGTATAGCAAATAATAAAACAAGATGAAACTTGTTAAATTGTTGTTTATATTTCTTATTTTTtATTTTTGTTGCTAAATGTTGCTTACACAGAGTAAAAATATAAAATATTGAAGAGATACGATCTAGGAGATCGGTACGCATTTAACAACTCTCCCCTACGTTATCGAATACGACTGCGAGTTAAATCCGTTCCCCGTGAAAATCATTCGAAAGCGGAGAGCCTAATTTATTAAGTTCGCCGATTTCCCTTGACGGTGAACGTCCCCAACCACGTATAACTGCTGTGTTTCAATTTTCACGGTTCACTTTACGTGACAAATGACATCCAAACGAGTTAAGACAGACAGGCCCTTAATCTTAATGTCTCCTTGGCCAAGTGACCTTAAGGATTAACACAGCGATTTCTCCCAAAAGTTTGTGCAGCTTACCGTGGCTCAACTCTGGCGACGATCTCGCCGTCTGCGTTTACCCTCACGGCAATCCGCTCGAGTAATTAAAATAATTAAAGTACTTAAAGAGCCGGAGGAATCGGATGTTTTACGACCGATTGCAATTCCTATGTTGCCTCGCCGAGACGAGTCTCAACAGTAATTTTATGACTGAGGCCAATAGGGTCTCGAATTGCCAGAAATTTCCGGACCATTTGCTCTCGTCTTTCAAATTCAAGATAAAACGTTTTTGTTCCGTAGTAAAGTTACATCCAGAAATTGTATTTTTAAGATACTTCATATATTTTTACTTTATAAAAGTCGCTGCGCGAATAAACGACGAATTTAAGAATAGTCATCACATATAATTGGCAAAAAATAAAAaTACATGATATAATGGTAAAATAACATAAGATTCATGTTAAATTATATATCTCTATTTTtAAAGTTTTTTTTTTAATCTGTGCCGCATAACTGTCAAAATTTATAACAAAGGGATAAATATTCACATAATTAAACTTGCAACCTCTTAATTGTTTGAATAAAAAAATTTAACAATTGATAACAGAACGAGCTAATAAGAGTCAGCGCAATAATTGTAGCACAATTCTTCTTAAATTAATTAATCTTAAAGTAATTATTATCAATTGTTAAAAATTTGGGAGTCTCCATTAATTCAATTTTACTTTAAAAAAaTTTATTTTAATTATTGTGAGACATTCTTTTTTtAATTATGGTTATTCTTCGTTATAAATTTTGAAAAAGCCACAGATTTAAAAAAAACGTTGTATATTATAATAATTATATATTATTAATTGTATGTTATAATTAACTTTACATATTAATATCTGTGTGATAATTAGTTCCTAATTTATATAAAATAAAAGTAATCATTTAAATTCGATTACGAATAAATAATTTTATTTTAATAGTAAACGTTAACGTTAAAAAGTGATAAATATTTTTCTCGCATTTTTACATCATCAAATAATATACATTGTAACAAAGTGTCTATTTGTAGGTGCTAGAATGGTCCGGCGTGTCTTTGATCGATCGGAGCTTCGAAGAGGTGCAGCAGATAATCGAACGGACCGACGACGTGGCGGAATTAGTGGTAGAGCATACGACCGAAATGTAAGTCAATGCATGTAGTAATATTACCGTAAGACAAACGTGAATAGACCTAACCGTAAATCAATTCTCTGTACTCGCATCGTGTGTTCCTCGGCTATCAAACTCTACGGCACTATCGCAAAACAGCACCGGAGATTTGCTGGATGATCCGCAAGCCGGAAAAACACCTACAAATTTGGGCCTGCTGATGGGTGAGTACTAGCAAAATTTTCTAAAACGCGAGTGGTCGAATACTACATCAAACATCCAAAATTTTTCCTATCTGAGACTAATGTAGAAATAATTTCTGATTATGTTATATAATTTTCGATAATACGTAAGTGACTTTGACGTGTTTCCATTTTCGTATAAGTAATTGTAAAGGATAATGTTTGAGATATGTTTGAAGATAAAATTTTCAAACGTTAAAAGAAATATTTTTTTTtAATATAGATATTTTGTTACGTAATACATTTAATTAATAAATTGACAGTTTGTGTCTGGTCAGTTTGATCCCCGTACGAATGCTTACAAATTAATATGAAAATACCAATTTTATATAAACCCGCTAGTAACTCCCAACAAGAGACCGCATTTTATTGAAGATCGATATAAAAGTTAACGCGTAGAAAATTTCATTACATAGTTTCCGTAAAATCGGCTATCGTTTATCGATTTTCATGCCCCAAATACGAGTTCTACGAAAAGAATTTTACATTCGAGAGAGACCAATACCCAACAAAGTATTACGTATCCTTTACTGATTTGTAATATGTGATATGACTGTAAAACTCAAGTTTGACTGCATTTAATTAATCCGTGGTCAGTGGTGAAGATTGGTCACTTCGAAAGCGGGTCAACATAGACAAAAGAAAACACCTAAAGAGATAGCAGTCGCGTGGAAGCGTGCCTCTATACATTCTAGAAATAAATGCCTCCTAAGTAATACGAGCAGTGTCTTTTTATACAACAGATAAAAAAGTTCCGTAGTATTCTAGGACGGGGATGGCCTCTGACCGCTGACACGGTTTCGTTCTGACCTCGAAAATAGCTACAAAACGGACAAGTATTTTAGTATTCCTGAGTATTTGCTAAATTATTTATTCGCTACAAATTGGCCGTCCGTTCACAATCGTGAGCTGAGTTTCTGCATATAAAAGTATGCAATTTTTTAATAATCTCAGTCATTAGAAAATAAGTCATTACCTACAATCTGCTATAAAGTTGATAAAAATCGCAATTTTAACATTTTTTTTTTttATAACTCTGGACTGAGATGAGTCACGAACTTTTATAAAGTTGAAAACGAAGGATCTGAACTACTGCTATAGGAAGTTTATGACACGTCCCAGTTCAGAATTATTAATCATTAAAAAaTGTCAAAATTGGGTTTGTTAACAACTTTAATAACAGATTTCTAAAAATCCTAATAAAGACATATCACACTCTGATTCATGTTTAGCAGCCAAAAGTACATGAGAATGACTTGTTAAACCTAAGGCAAAAACAGTTTGATTTTTTGTCGCTCAGTGTTATTATTAATCATTATTATCCCTCTGCAATTGATCTTTCTACTCTATACGAGAATAAAAAAaTAATATGGCTCAGAATTATTGTATATAAACTATTCAATAAAAAATGTTGAACTTATCGTAAACAAGAATTTAATTGTCGGAACACTCGGTTTTCACAGAAAAAATTAAATTTTTACTCATAATTTCGAGCTATATGTTTTTTtACTCTCGCATGACGAGAGAGGATGACTACTTCAAAGTCAGTGTCATCGCAGTCGTTATGGAAAAAGAGTTACGGAAGCGACATGAGTCACTGATATGATGCATTTTGATATATGTTTGCAGAAACCGAAACGGACAAAACGCCCTCGTCGCCGACGCGCAGGAAACTGCCAAAGACGCCGGTATAACGAGTTAATAAATTGACACCTAGACACATTGACCGTTTCTCTCTTTCTCTCTTTCTCTCATTATCCTACACGATGTACACGATGCATACGCAGACTCGGGGATAAGCACGCTTAGAAGCCGAGAATAAGAGCGTAAGGAAAATAGAAAGAGAAAGGCGCAGGGGAGCAGCTGAACAAAAAAAAAAaTGCTTCCACTCGCATTAGTCTCTCTTTGCTTTTGTATATAATAATATAAGTATAACTCATTAGCCGTACACGAACACGAACTGATTTGTGCGCACTTGTAAACGAGAGATGTGCACAGACAGCCGTGACGCGTGTGAAAGAGTGCGTGAGACCCCGCGGCTTTTAGCGTCGACGTGCAAATCAGTCAAAGTGAGCGAGCTTTGTGTGCTGAAATGTATCGTACGCGGTTTATaAAAAAAGAAAAATGCTGCTGTAATTACAATCAATTTTAATGTCTGCAGATCAATTTTGGCGACCAAACGACGTTCTGCTGGCAAGACTGCATTTACGTCTTCGATCATTTGTCCGATTATTCATTTACATGAATATAAACAGCGTGTTTTAATTTCAGCGTCAATATTTTACCGTAAGAGATGACTTACCGACTGTAACTGTAAAATTCACCCAGTGTGCGTGTACGTGCATGTACACACACACATACAGAGTATCTTGTTGCAATCGGTGAGTCATCTCTTATGATAAAACGTTGACACGGAAATTAAAACTCTCCCTAAATCGCAATTATTTTTTTTTtATATTTAACATAAAAAATCTATCTATCTCTCATTTTCATACGTAACTCATTTTATAAGATTTTTAAAGTTGATGCCAATTTACAATCGCAAATTGAGATTTTAATTATGCGCGTATATCCCCGTTGACACAGTTTACATAATGCTGGAATCAAAATGAACGACCGTATTAAGCTTTTACGATAAATATCGGATAAATTTCGTACAATTATATTTTCACCGGGTTTCAATGGTAAATCGTTTCGTTTGTCCCACGACTGTTCCGGTCTTCGATTCGTCGATAGCACCGGAGTTACCTCCTAAATTTTGTCTTTCGGTAGAAATCTCACGGATCGCCAATCTTATCCGAACGCTTAGTCGGCGGTACTTAAGAAAAGCTGACAGAAGTCGAGTACTCTGATCGAGCGTTATTCGCGAGGAGTATATGGCCACTTGAATCACGCGACTAAGCCATTTTTATCTCGGTAAGACACAATGCGGCACAATTCCACCGCGCATTTTCACTGATCGTGCGCGAAGACTGCTACATGTAAATATTGTACGTATACTTCGATGTAACGGTGTTACTAATAACGCTGTCCCCTTTTGTTTCTCTCGCAAAGCAAAAGCATGTCGTTCGCGTTGTCGCGGTCGCTTCAGATAAGTTTACGAGGATCGGCATCGATGACGAGGATTAAAAAGTCTGTCCGATAGAACGGGGGATACTCAAGAATTGCGTAGGCGCTTACTCTCGAGCGTGTTTCTGGAGAATTAGGCAATTTCGGGAGAAAGAACTGCGAGATAAAAATCCAACTCCGATTGATCCGTAATACATAGCGAGATAGCAGCAGGATAAAGTttttGATCTGTAGCAAAAACTTACTTCGAGTTTGCGTGATTTTTAGAACTCCAGGCGCAAGGGTGTAATAGAAGTTATCGTATAGCTTTCTAAACTTTAGGAGAAATGGAGATACGAGATTATCATCCATCGCGTTTTGTACGATATTAGTCGGAGGAAACTAATAGCAAAAAAATTGTCCGGGGGTTCGTGAAAAACCATATGGAAGAATTTTCGCAAATCGTAATAAAATGTGTAACCGCTCTTTCCTTGCGCGATTTCACGTTTATTCGCTATTTATTAGCTATTCTCTGTTTCGGAATTATTTCTCAAGCCGTTGCGGCGATATCAGAATATTTCAGTGGCGAACAACATATCTACCATCTCCGAAAGCTATTCCATTTTTATCATCGCGCATTTTCGCAATTTTGAAGATTTAAGGGTCTTAACGTATACTTTATTTTTTTtCTTTTTTtCTCTCTTTGAAAGAATAGTTTCACGAGAATTCAATCATCATATATTGCGGCTCGCGTCGGTTATAAAGAATTTATTGCTGATTACCTTTGTTTTATTCTCCGCCATTCTATCGGTTTCACTCGTTACCATCGCGTGCTCTCGAGCTCGCGAATGCTCCGATAAGTATCTTACCAGACGTGAGAGTTTTAGCAAGGATGAACGAAATTCTTATCGCTCGCCCAGCAGCCGAGCTTTTCTCGAATTAGTTATCAGATAAAGTTTAAGGACAAGACTGTATTGTAGCTAGTAAAAAGAAAAaAAAAGCAGCGCGCTCGTGATTTATAGGTTCAACCAGTGCCGTGAATATCCGATAACACACTGTACGAACGTTCCAATACCGTGATACGTATGACACTGTTGGTATGCACGCTGTTTTCCAATCGATAGGTGGCGGTCCAAGCCGCCCAGTTGTTGAATACCCGAGCGGCATATGCAAGAGAGAATCTCGAAAAATATGCTGCACGAATGTCGCAATTATTCCATTGAATCGTTACTCGTGCGTTGAATATTACGCAACGGCTCGCGTTTAAAGCTACTCAATATTCGGATAGTACCTTGCGAGATGTTTGTATGGAGCCGCAGTTAACGAACGTATCGCTGAAAGCAAAACGTTCGCGTTATGTGATTGCCTGACATTTGTACAAAATTTAAAAGAGAGCATTTTTATAAAGATACGAATCTTGAACAGTATGTAATTATTAACAGAGCCTTTTATAGAAAAATGATGCAAAAATATATTTAAAAAAAAaGAGCACACGATCCTGCTGTTTTACATTTATTTGCATATTTGTTTAATTATAATTTTACGCGCGTAAAAGTTGTAATGTTTAATCGTTGAAGTAGTAAAAATTCCGATTATTATTCGACGGCACTGGTTTCTATCGGCTGATATCGATCGTAGAACTTGTCGACGCGACTCGAAAGCAACTTAAATTTATTAGTATCTACGTTGTATATGATCCCCTTTAGGCCATACAGCAGCACTCGTACAATCACTAGCAGAAATGCGCGTTACGGTGTACGCCGCTTTGTTTTCTTCGACGCAATCGCGGGGGTGTTCTCTCATACGTACGTCGGAATTTCGCAAAACGACTTGAAAAAATCGTGAAAATTGGGAAAAGACAACTTTTTGGTTACTCAATGAAAAATTCACAAAGTGTAACTACAGAATTGCAAAAATTTTATATCTTGTTTCACGCAGAATTTAATTCTGTTAAGAAAAGCGATTACTCAATTTTTAGTTTTCTCCTTTTAAATAACGGTTAGTTTTGCAAAAAATATTTTCTTAAAATACACTTATCATTTGCTTGAAACAAGCAATATTTACTTGAAAATATATACTAAATAAAAATTATTATATTAAAAATAATGTAAACAATATTTGCTTAAAATATTTTTTGTGTACACATAAAAAGACATATATTTGAATTATATAAGTAAATATTACTTAGTTCAAGTATTCCGTAAGTTCACATAACTACAAATCTATTATAAAATGTCAAATTTATTCAAAATATATTCTGGTAATTTATTCTTTCAATCAAGAATATTAAGTTAAAACAAAAATTCAATTGGTCCATTATCCTGACTTTTCTTCGATACAATTTTATAATATTCTTCGAAAGAGTATAAATTCTTTTTTTCAGCACGTGATAATAAATTTTTCTAAACTTTGTATGAGTAAGTAATATTTTAAGACAATTATTAAGGAAATATTTTTTTGTTAAAAACAATTGTTACTGACGAAAAGAAAAAAGCAAATTAAACGCTTTTCTTAACATCAGGATTGATATTTTTTtGTGTGTACCAAAAAGATTATTTCATCAGATTCATTAATTTATTGTTATTTGCTCGTTTATTATTCATGCCGTTATTGACAGTTAACGTCATTGTAAATATTAATAGGTGGAATCGACTTTATTATCAGTAGAGACGCGTTGTACCCATAGCTATAAAATTAAAGGGAAAATTTCTCGTTGAAATGTTACAGTCCCTCCCCAATTGAGGGAACATACATATTTCACGTATCATCGGCGATCAAATTCGCCGTCCCGGAATATTCGGCGAGTTTCAATTTATTGCCTTTTTTTCCCGCGCGTCATTAATACGCAGAATTTCGAATGCTACCGAGACCTGTCGCATGTTAAAATAATTTTATCTGTTAGCGCTAGGCACCCCGGCCTCTCGCGCAAACTGTTGATTCAATCGTTTACCGATTCATCCTGGCGCGGCGGCGCGGCGTGTTATCTTAACGGTCCTCCTAATTAATTATCGGAGTACACGACAGATGAATCGGCCGGGTGTGTAATTACATGCATCGATCAATCGCGAGCTTACGAACACCTCCGTCCGTCGGTTTCGCACACACGGGGAAGAGGCAAAATGCCTAAGCGACACCGCAACCGATTTCTGTCTGAAGAGAAAAGCTTTCGTACAATCAATCGTAGAGAATCGCCGTGTGAGCACAGCCCGTATGCTCATATCGCCTCCGAGGATTTTTACGAAAGTCATATTCGCATTTTCGCGAGGAGTGTCAGCATCGGTCGCGAGATTATTAGATATCTGGGAGCACGAGCGATTGAAAATTTTAACATGTAAAAAGACAAAGAAAAGAGATTCGTCGCCCAGATTCTTACTCTAATACTACAGAAAATGTTTGATACGTCCTACATGTATACGTATAAATAAAAAAaTAAAAAAaTAAATTTGTAATGCGACACTGCAACTACTGAATTTGATAAAAAaTTCAATTTTTTGGAAATTTATAGCGTACGGGAATTTGTTTATTATCAATTATTAATATGTGTGCAATTGAATAGATGTATTGCGTTAAAAAAaTATATATATGTATATATATATGTACATAATAATTCAGGAAATATGCGGGATCTTTTGTACATGAAAGAGTTTCACCAATTGGAATTATAACTCTAATAAACAAGACTGCTTAACAATAAAAACAACAGTAATATGGTAACAATAGCATTGATTTTTATGAACCATCAGATATTTGATATAAAAATAGTGTAAATATGCGGATATATGCTAAAAGATAAATCAGGGAGTGTACTCTAATTTTGTAAAACAATTTTCCAAAAATTCCCGGAAAATTTTATTTTACAAAATTCTAGGTAAATTAAAGCAGCTTTTAACGCAGCTTTGAAATACCTTTATTTTATTATATCTTTTAAATGTTTCTAATTATACAAAGAAAAGTTATTTGAGCTCAAATAATGAAAAAGTAAAAATAAAGTTAAATATAGTAAAAGTATGGAATGCGAAGCGAGCACTGAAAAAGGAACATTTCTTGTTGCATTAATTACAAAACTGAGAAATTCAACCAGTAAGTCTGTTTGAAAACGGACGAATCAGAAAGATTGAATTAGCGGATTATAGTAAAGTCTAACAAGCATTCTAATTATACATAAAATCTCAAATCCCATTATAGTAATCAGAAATTCTACTTGGTTTCGCTACAATTCACTCAATCGTATACGTTAATATAATAAAATTATTTTTCTCAGTATAATTAAAAACATATATACGCTAATTAACAATGTGCTGTCTTATAATGTCACTGATTTTTAATAAAAACTCGCAAGTCACACAAAAATGTATGTGAATGAGAAAGAAACGACAAAGGTAATAATTTTGTCAGAAAGAGAGAGAATTAATATTTAAAATTAAATTCCAAAAATTTCCTTAATCTCCAACAAAATTCCAGGAAAATCCATAATATGTATATTTTTTTTTTtCAAAGATAAAATAATAGAAATATTCTGAAAATTCCAGCTTTTTCTCGGTAGTACGCACCCTGATAAACATATATTAAGCAATATTGCAACAATGAAATAAGAAATAAATCCCGCAGATTCTTGCAAGGAACAATATTAATTTTtCTAAGATTTCTCTCTATATAGACATAAGAACATTTTATATAGTAAATAGTCCTCCATTTTTAACGATACTATACTGGTGCTATCCTATTGATATAATCTCATCACTAAATCAATAACAACTGATCCAATGTGATACGTCAAAGTTTAATGATAAATGACCGACAAAGCTCTCTTTCTCTACTGTAATCGTGCATATGTACCGCAAACCTTCAGAATCACTCGTGCTCCCAGAAATATATTTCCCGAATAATTCCTCGTTTTTCTCGAGACAGCGAACGGGCGGAAGCGGAAACTCGCACGGCTCCTAGATATTAACGCGAGCTTCGAGACGTATAGAAGCGATTGTAAAGCGCGGATCAACACAGGAATGAATCTAGCATTTTAGCGCAGTTTTAGATATACTGGGTGTTTTGATAAAGTACTCATCGAATTAAGAATTCTTTCTCAATCGGCGTAAATCCGCGACGTGAGTGGAAGCTGTTAAGTTGAAACCTGGGTTTTCAACAATTTCATAAATTTCTATCTCTGAAAATCGTATGGGACATTTATTTCCAATTTTCGATGTACATTCGCGTAAACGCGGACGATTGCTGGAAGAGCGTTGCTGCTTCCGGTTTTCTCACACGCGTTTTTGAAAAGACTTGGATTAAAAGTCGAAAGGCTAAAGCCAAGCTTCGATAACTCGACCAGGTTTCGGCTTCGTTACGTCACTTGCAATAAATAACGCGGATTCGTCTGGATATATCGCATCAAGCCAATCATCTTCTCTCTTCGATCGGCCGTGTAAATATTACTCGATCTACAGACTAGAACTTTGTTATGGACCACTGTATCTCTCGCGAGAGAGATTTTTGCAGTTGGACCAATAAAAGTCCATATATAGAATATGAAGCTTGTTCGAACGCAATTTGCACATGTCTGACACGGAATGTCATTTATAATGCTAGCAGCGTGACAAATCGATCCCATGATTCTCCGTGTCACTTTTACGAACACGAAGTGGTCGATTCACGCGGTACATCGCGCGAATAAAAAACAAAAAACGCCGAAAATTGTTGAATCTGCTCTTCATATACGCGTGCTACATGCATTAATTATATTATATAGGGTGTCTATGATTTTTCACTTCCATCCTCTATGTTTCGGAAACATAGTACAAAATTGTGGAAAACCACGAAATGTGTATTCGATCATTTCGAGGGGCCACTCTTTTAAAGGGTGGAGTAGCCCCTCCAAATAATTGGACATGTATTTTGCGGTTTTTCATAATTTTAAATTTTGCGAGCAGATTTTATAGACACCTCGTAATATTTATTTATTTATTTATTTTTTTTTTtAATTCAATATATTTCGAATATTTAATAAAaTAAATAATTTTAAAAAGTGATTCTCTTTCTTATGAATTTTTTCGTTAACCAAGTATGTTAAATAAAAATAATAAATAAGTTGCGTTAGGCAAAGATATTTTCCAACAAAGGCATTATATCTCAACATACGTAACTGCATACGTAACATAAAAAAAAATTTCTAAATTGACGCTTTCGGTCAGACGTACGCATTTTTCGCTCGGACAAGTCGTGTATATTACCTACAGATTTCTACCTTTATGAATGTTAAAGGATCAGATGGTATTCGTGCAGATTTATCGAGTACGTTTAGACGAAAATTATGTGTTTTAAATACGATTATCGAGAGTAAGACTAAGATTGCTACAGTGCTTAGATTTTAGACGCTTTCGACAGTTTAGGGCGCAGCTTTCCGAATCTTTCGGGCGCATCCTGCCTTTTCATCCCGATCCTGTAGAAGGATGTGAGAAAGGCCAAACGTTGTGCGCCACGCGTGCGTTTGTCGCCAGTATGCATTTACCGAAATAGCCAGGATTATTATATCTGCGAGAGCGTGCGTGTATCGCCGAAATTGATGAACTCTGTTGATCACGGTTCTCAGAAAAATATGTGCGTTTGGAAAATGATTGCGAAAATTATTAGTACACTTAAACTTTTCGAGTTTTTTTTTtACGGTAATTCAGGAACCTTTTATTTGTCATTTGCACAACTGGGGAGAGCTATAAAACCAAGAGGGATATCTCGCTCATTTACGTTGCGGAATGTACAAGGTTGACCGAAAAAATCCAGTGAGTGGGAAAAACCGTAGTAAATTCCGAGAATACTTGAGACTCTTTTACTATTTCAAACTTTATCCAGTGGTACAAATTAGCAAAAAGTAAAAaTAATTATTGCATATTAAACGTGTTTATACAACTTTGTGCAAAATGATACTTTTAATTGTAAAATTAATAAGTCATTGATTTCATTTTCCTTTATTGTGACTAGTACAACTTATTAAGGATGTTCTCAAAATATAATTTTTATATTTCTTTTTATAGCTTAGAATGAAGCCAAAACGTTTGACGAGAACGTGTAGTTAAATTTTGTTTAATTATATTATCAAAACACAATAAAATAAATTTAATCTAATCAATTTGCGCACTGACGACCATGTTGATTCCTGACGGCTCATCTTTTCGAGCTGTAGCGATTAATTTTTTTAAGGACGAGGAGTCGAATCCAATTTCGTTAGAATTTTTATTTTCTTAATAATAATTAAACTTTGTAATAATAGTCTTTTTAATTTCAATTATAGTAATTTTAATTTGCGAAATACTTTTCTTAACAAAAATTTCGGAGATACAATTGTTGCTAAATTTTATATTAATTTTTAATTTCACAGGAAAAACATAATAGTAACAGAATTAAAAATTTGTATCTATATAATTGTTTCGCATTTACTGCTCAACAGCTTGTAACAAAAACTAATTAATTTACAATGTCGATTCTTATAACCTGTTACAGCTTTCATTTCGGATAAAACTTGAATTGGAACAGATGTTTTTCAGTTGACAATACTCTCTCACCGTTTTCCATTTATTTTATCGTCTTTGATAGAAAAAAGTTTCTGCCGGTTTTTTTTTTTtGAAAATACCGATTTTATTACTGGCACAAACTTTATAAAAAAaTATGGCATTTTTCCTACCTCGTAAGTACTTGTACAAATATAATCAAACAACAAATAACATGCGAATATTCTACATTACCTCAATATAGATCTCGCTAGATGTACAACCTCGGTGCTCAATGTTCCTCGAGCTCTTCGCCGTTCCTCAGTTATCCTCAATGCTCTTTAATGTTTCTCATTGCACTCACTGTCGCACTGAAAGAACAATTTGGTTGATAATACAGATATGAAAATAATTATGTTGGATCATTAAAACAATTACATTGTATTGAAAAAAAGATTTAGCAGCTATTACCAAATTTAGTAAAGTTATCGAATTTTTAATTTTTATAATCTCCCGCTTATACAAATTATTATTGTTCAGCACTACCCCAGTAAGCATAAAATCATTACTATAATTATGTTATTATACAACGATGTTAAATAAAATGTAACGTATTCAAATATATTTtATTTAACGTTATACAACATTAATATAAACTCTGCTCGTGACTAGATTAGAGATAACGTTTTTAAAACATTTCAAAGAAAGTAAAAAAaaGTCAGCAATATTATTTTAAAACGCTTACAAGTGCGTGATAACAACATTGCTAAATGTTGCTTTAATGTCTCTTGCCTATTGGGAAGAACGGCTTAATGACAAAAGCCTGCTAACTTTATCTTAGAAAAAGATAAAGATTCGTGATCGCGTTCAGCTCGTTAGCACAGTAAACAATCGTCCGCTGATTTATTTCACACTTCGGCATTCGCAATATAGTGTACACAGCGGTGAGAACTTACCTGGAGCGTTGCGGAATAATGCGCGCAATTGTCTCGTCTAATGAACGTGCGAGGAAAATCACTGTAACGCGCCCGTAGATTTCGTCGGATTCCCCGGATCTCGGTGCTCCTCCTCCTCCTCCTCCTCCTCGGTGCCCGCTAATGAATAGACACACGTACTCGGGCCGCTCTTCTTCTTTTTCTCAATTGTGTGACCTTTAGATTTCCGAGTCTTCAATTAAACGTCACGGATTCACGATCGTTGAGCACCGAATCGCCAGAGAGCTCGGTTGTCCTAAGGTTTGTTCGCGTCGCATGCTCCGAGAGCACTTGGATCACTTGGATCACTTTTATCACCAATCGCAGCATTAgCTCTAATGCTGCGATTGGTGATAAAAGTGATCCAAGTGATCCAAGTGATCCGAATGCTCTTGGGGCACGCGACGCGAACAAATCTCTAGTCTACAGTTCAGGGCTCTCGACGAGGAGCGAGGAGTCCGTACGAAAAAGATACCGTTCGTATCGCGCACACACGATCCGGCGTAAACGCTAAGACCGATTCGCGCTCATTGTCAGAGGCACTAGTGGGTCCTGTTCCAACCCACGAGCGATAGAGACAGACCCCGGCACCGTTGGCGCGTCGAACGTGAATGATGAACCGTAGGACGGTCGCGAGCCAGGATTTTCGACACCTCGAAAGCTTGTTGCGTACTCGGCCGTGAAAATACCGGGAAACGTGACGTAGCGCGTCGGCGAAAATAATGAAAACAATGAGAAACGACGCGCCGCGAGGACGTCGAACATTTGCGAGAAACGACGACGCGCTGCGAGTAAACATGGCGGAGGACGGGgAGGGCAATGCAGCTCGCTCCCCCCCCCCcTCCACCCATGCCGCTCGCCCCGTGCCTCGATACTATCGATCTCGATCAATCCCTCGATGAACGACGTCTCGATTCGTTTCGATGTCCGGCGCGTTCGGCGAACGCGAACACAAATAAGAACGCCTTCGAAATGCTCGGCGGCCGAGTACGTATGTATGTACATATGTACCATTTGGCGTCGCGACGCTATCGCATCGCTCGATTCGACGTTTTGCGAAATAATCGTGTTGAAAAGCGGATTTTTCCGAACGCCAGTCCAGTCGAGCGAAGCGTGAAACGTAGCTTCGGCAGCGAGAGACATACTTAACCTTTAAGTAGGTAGGTGGTCGAAGGTTACGCAAGTAGGTAAGACTAATTATATTTTACGCGTAAAACACACAACTCTGACTGCAATTATAATACTTCTCTTGGTAATAGACAATTTATATAAATTGTAAAAAATGCGCGCGCGCGCGTGTGTGTGTGTATGTGTACGTATGTGTGGGCATGCTTTTGTGCATGTTTCTTGCGTGTATGAGTATTTTATAATTTACTAGATAGCGCGTCTTCTTTTTTCCACAGCTGTTCATTTGTTAATTTAATAAATATTTATATTAGTTAAACAGTTATGTAATTATTTGATAAAATAATTATATTAAGTAACCATTTATCTAATTATATTTAAATTAATTAATAAaTTAAaTAATTATTAAaTGAGCAAATTtATAACCAATCGgAAACGCGGAAAGGAaGCTTCAAGTTAGAtAAGATGTtAATTTTtAAAtAaTATATATTGACACACACACACACACACACACACACACACACcTATTTATAtAGTATTTATAaTTATAATtAcNNNNNNNNNNNNNNNNNNNNGTATTTTATAATTTATAAATTACCTATTATCAAGAGAAGCAAAGGGAAGCACAGACTTTTGCATTTTCTTTATCTTCTTAATGTTTTTAATATTATATAGTTTTACATTTAATATATTGAAATCAGATATACATATTAACAATTTTAAAACTTAATTACTTTTTTTCTATTTTACTCTATATTATCTAATTTACAATAGTTTACATATTTCACATGTTTGTCTACATAAAAAAAGTTTGTGCAAACACGTGTTACGTATTTGTTCAAGTAAAAAACGAGTGTAGACGTCATCTTGACTTTATTCAATTTCTGTGATACACAATTGATCCTTTGACACTGAGGATCGATTGTGTATCACATGAATTGAATGAAAATTACAAAAGTGAGCAAATCCATTAAATTTTGATAATAAAATTTATAAATATTTTAGTAAATTTATTTATTTTTGTAATTCTCATTAAGAGTTGCATAATACACAATCGACCCTCTGATTTATTATACTGAACTCGATCACGTGATAGTCTTTTCAACTTGGCGCGTCCTATACGCGACACGCGGAAAAACAAAGCGCAATGGCTTGTTTGAGACGCTAAAGATAAATCTACAATGTGCTCTTTTCTTTTTTCATTATTTGCTTTTTACCTGTTGCCTTTTTGCCTCTTTACACATAATGTTTTGTTGACATTGGCGAGATAAAAGCTGACGAACTCCGAAAGAGACAAGAAACGTGTGACAAAAAATAGGTTTGTCATTAAAATAGTGCGTAATAAAAAGGTAACAGTCGAAAAGCAAGAAACAAAAGGCAAAAAACATACTGTACATTAGTCTTTAAGGAAAATCTTGATGGCATCGATTAAATTACAATGAAAAGGCAATTCGCTCGAGTTTGTTTTTCGCCAGTGAGATAAAATACGACGAAATGATAAATATCTTCCGCGTAATCGTTCAATAAAGAACTCTGAAAGATATCTCAATGTTGTATTATGCATCAATTTTAAATATTCTGCTCACTGGGTTTCTTTAATATATTTCACAAGAACAAGCTCTCGTATGTATCTCTCTAACTTTAATGAAATTTGGTGAATTCGTAAGAGTAAAAATTTAATAAGAATTTTTTTATCCACAACCGAGCACATTTAAGGGGTGAAATCAATTCTTGAAGATTAATTAAATTTTTAGCTATAATTTCTGAACGAAGCATGCTAGCGTAATTTCATAAATGTATAAAATGTACAGAACTTCGAAAGAATACAAATTTCGCCCCTTACACACGTTTTAATTGCCAATAAAGAATGTATATATTTTTACCCCCTCTACAAACCTATCAAATTTTATTTTAAAATCAGAGAAGAACTGATTGGGAGCCTGTTCCTTGTGTCGGTGCAGTAAATTCTTTTTCTCTCTCTCTCTCTCTCTTTCTTATATTTTATTTATTTTATATCTAATCTTTACTACATATATTTAAGACGCAGAAACAGAGAGTGAAATTTACACTGTAAAATTATGTAAAACATTTGAAATAACGATTTCTCCAAAATCAACAGAGTTCATTGATAATCGGGACAGTTTGACGAGAGTGCGATATCTTATTGCCATATAAGAAACACAAATCTACGTTGTATACCGAAAGTTCTGTCTCTGTTCGCGCCCTTGTATGTCTCGTCGATGGTGGAATTCGCGAGAGGAGCAAGACGAATATATAGACGGTGCCTCTAAGTTGTGTACCATTATTACTTTGGCAGTTCTTAGAGCTCGCGCGTGTAAGGGCCGATACCTCTTCGTTTCCGATGTTGCAGCGTCGATTCTAAACGCCTTTAGCGAGTAATGACGTGAGTCAGAACTTTGTTAACGTAGAGAGATTGAAATAAAAAAAAAAaaaGAAGAAGCTTAATCTTACCGAGGCGGAAATATAGGGATTTCTGCAAGCTGTTGTTTATTAAGCGATATAATAAGATTTGCTGTACGACGTATCTGTGTGGAAAATATAATAGATTGATCGTATATAAATTTTATAACTATTAATAGCGTGTAGCACTTCTAGGGCTAATAGGCACGAGATCTGTCGACTCTTCCAGCGCGAGCTCTACGATAACGGCATTCATCGACTTCGTACGTCGTGTTACTTTGTAAACGGACTTGAAGCTTACGATGTTAATCGCGCCCTTTCCTAAAGCTACGTTCGCGCATTTTAAGTGTACCTCTCATTTTTAATTTATGCTTTTTTAATGAGGCGAGGCAGCATGAGGCTGAGAATTAAGGAAGCTCACTCGCGCTCGACGGAAATCGCCGTGCAGCATCTTTGAGTCCCTTTGCAGAGTATTTAAAATCGGATCATAAAATTGGATGATAGTGACGTTCGCGCGTCCTGCGGGATCCTTTAGCGACGTACGTACGCGATGGGGCAAAAGGAAAAGAAGGAAATGAAAGACAGCGCGCGCGAGCGTGCCCGTCGCTTTCGTGTGAGAGAGAACGAATGTCACGCTTTTCACTTTTCGCTTTTCACGTCAGAGTGGCAAGACGTGTTGCTACAATAAACGCGCAACGTGCAACGAGAGCAAGATTCGAGAAAGAAAAAAAGAAAAAAGAAAAGAAAAACGCGCAGCGCAAGAAAACGAAAGTGTCAGTTGGGGCGAGTTGTGTCGTTGCTGTTCTCCTTTCTTTGCTTCATTGTTGATTTTCGCGCGGATTAAAATCGCCTGGAAGCGATCACCGTCGCGAAGCACTGTCGCGAATGTCGAATTTCTCACTTTGGCTCCGAACTTGGCCGGCGACCTTTACTTTTTCGACAGCTTGATAAAAAGAAAAAAAaCAGGAATGGAATAGTGTCGAGCGAGATGTTGTTTATTCTTGTTAACCGTCTGTTACAATTAATATCGGAACCTCAAACGTTTTCCGTGAAACGCTTGCTGGAACGATTTTGTTCTCACCCAGTTGAATATCGCAGCCGACTATCGTTTAGCGCTTGAATATACATATTTTCAAGTTCAACGGATTTATCGGATGCGTGGCACACGTGAAAACGCGGAATATTATTAAATGTAGCGTTACGTCGCTTATTTATTTCGTATTTACCATTTTACTTTGGTATAATTTTCGAAATAAATGCACGCTCGATAAAGGAAGAGAGTTATTTTGCAAATATGGGTAATACCGCATTTACAATGACATTTCAAAGAGGTTTGCTTTACAGAAAGTCACGTTTACATTTCTCTCTATAAATTGCTAATAAAATACGTACACGTATATACATTTATATGTGCGTTACGCTCTTTAATTTCTCCTGGCAAAGCTGCTGGACACTGTTCCAGATTTTCTCGGTATAATTTAAAGCCTGGATTCGCGATGAGGCACGTCCTCTACTACCTCGTGTTCTCGAAAGAGCGGTCTCAAAAGCCTGAATGGAAAGGAGAAACGGCGGAAATAGCTAAAGGAGATTCTCGCGGAGAAGCTCGACTATATGCATACACGGAGGCTGTGGCACTCGATCTTTCTTTACGTAATTTACCCTGCCAGAGAAAGATCATATATATGTATAAATGTATATCCATCTTCGTTTCAACACCGCTCTGTCTCTCACTCTCTCTCTCTCTCTCTAaCTGTTTCTTtCTCCCCcTTATCACATTTTTGCACAGCTCCTCCGTTTCTCTTTTACGTTTAGATGTATCTCGCTCAGTTACAATGTATCTCGTACCCCTTTCCCCCCACCGCCTCCCCCACTATCTCGTTCTCATTCTTTCTCTCTTCTCTCTCTTTCTCTCTCCCCCGCCCCCTATCTCCTCTGTCTCTTTGTCTCTGAATCTTTGTCTCTTCTCGCTCATCCCGATGTACGATGGACTTACACGAGACTCCTCTCTGGATCTCTACACATCTCTGCTCCGTCTCTTTGCTCTACGTTACTTTAAGTAAATCCGTTACTTCCACCCATACGAATGTACATACTCGATGTCATCTACGTTTCTTTATATTATACATATATATATATACATGCATATATATACGCAACTGTATGTCTCCCTGTATATACCCGCTGATAAAAGCTGACCGCACCGTGTGTAAAGACAAAAAGATCTGTAACGATCAGAAACCAAAAAAAAAAaGAAAAAAAaaGAACTAGACAATCCGCTGAGACGAAAGAGAAATGAAAAAGACATGAAATGTAAGTTGTCCATGTTGAGCAAGTTTAGCATATTGGTCCTCCACGCTACTCTCTCCCAACTGGCACGAATTCTAGTTGTACGCTAGCGTTTCTTTCCTCCTTGGCGGCTCGTTTTtCTCACCTTtCTCTCTCTCTCTCTCTCTTTCTCTCTGTCTGTCTTTCTTTCTCTCTCCCAATTCTCTCCGTAACGTCTTTGGCTGTCTCGTTGTTTAGCTGAGTGATATTTCAGTTCATAGATCGTATACCAACCTCTCTCTCGCTCTACATACACACACATATGTATGGCTCTCTGTCTTTCTTTTtCTTTCTTTGTCATTTTTTCCACCCCTCCTTATCTGTCCGCTGCCCTTAATTTTGGTTGCGAGCGCAGACACACGAACACCAAACTCGTCCTGAGTGATGCACAAATGCCAAACGTCCGAGCGCATTGTCATCTTTGCGAGAGGTATCGCTCGTGGCGCGCGCTCGCAATTGGGATGCTGCGACTAGCTATCGACGGCAGTATGATCGACAATTCATTCAACGTCCCATCGATATGCAACGCGCTCGGCGAGCACGCGGTAAATAAATATAAACGAGAATTCAACGGCTCCGCGTCCGTTTGATTTTTTACCTTTGCTCGAATGCGTGCGTTTTTATCCAATGTTTGACGACCGTTCGGGACCGTTACGGAGCGACGAAGCCGATAATCTTTGACGATAACGACGAAACAAGCGCGCGGATCGCTCGGATGGAAAATGCGGGCGTTTGGTTGTTGTTACATTCTCGCTTTTCCCTGGTATATGTATACGCCGACAACCGGGGGAGGTATGTGCACAAGCGCAGATTTAATGGACGCACTTCCATCGGATACGTCGAGAATGAATTTTCCCAGGGGGAAAAGGGGGAGGCGGGAGAACGGTGTTGCGAAACGTATCACAATGCTGGCCGATTGTTATACTGGGGAAATGCGCGCTTTGGAAACAACCGTAGACTGACATTGTACATAAATGCTTGTCGCAACGGCTCTTCTTCGGCTTCAAAAGAATTTATGCACGTGTAACTCCAAAGCGAAACGGTATATCGATGCATCGGGAAAACGTTTGATAAACTCGATCTCGAAAACAGAGTGTCATGAATAATGAATGATATTAGTAATAATCGATCGTTCGAAAATTTAATTTATAATTAACGTGCAGCGTTTGGGAAACGTTTTCATAAGCAGCTCGCGCAAAAAGCAAAATAATTTTCCAAGAGAATTTTTTTATTTTTTAATACTTGATTGATAATTTTCATTAAATTCAACGTGATTACCGAAGCGGTGAAACTTGTACGCGACAATCCTATTTTAAACATGTAAGATTATTATGCGAAAAGATAATGGGAAGAGATAGTAAAGTTGGGGGTTAGATTATTTTCGTGATTTCTTCCCGGAATCTCATCGTCATCCTCATTAAAATTCATTTTTCACTTTCTACTTTAAATCGGGCTAAAAAGATTCCCCCATCCTCGCCCGCTTTCATCCGCGATAACTTTTCTATTCCCATTACCGAGAGACCGCACCTGTTAACCGAGATTATTCGTAAAAATAATCTCGAAGCATAATCTCGGCCGTCTTATGATCATTAATTATCTTTTCATGTTGTATTTGCCATTTTTCATTTTGAACGATATGATTTTAAAAATATATTGCAATGATTACACATCTATTAATAAATGTTTGCAAATTTTCGTGTAAATATTAATAAATTTATAGCAATACTATACAGTTCTCTCGATTCTAGCTTGGAATTTTATTTACTGTAACTTTTGGCATAATTTTCAAGATTCAATTTCTCTAAATTTGCTAATTAATCAAAATTACTGCTACTTGTATCTTTCGAACTCTTTTTCGTAAATATCACTTTATCTAAAAATTGACTACGTTACAAATATAATTTTGAAATTAGCATACCATCCGAAAGTTTAGCCATTAGAATTACCACACTGTATCAAATTTCAGTTTTGAAATTAGGATATTAGATTTATATTTACATTACGAATTCGTATCCTATTCCCGAAAACTAATGTTTCACATGAAATAACATTGGAGCTATGATATCAATTGGTTTCAACTTTCATTTAAATGGAACAGCAATAGGTACGATCAATTTGCATAAACAATTTCCTTTGGGAGAGAACGCAAAGCAATGGTAAACTTATTTTTtCTCAAATTGTTGTAATTCTAAATGGCAGACAGCAAATTGCATAACAGATATACTATTTCTAATGTGCACGTCATTGTCAGTATGACTTATTGCAGCCGAAGAAGCGCGTCGCGACGATACACACTTGTTTGCTTGCGTAGAAAGAAACCTTTTTTTCAATAAAAACATCTGTAAATACGTATTCCATCAGCTTACAGTTCGGGAAAACCGTACGTGAAAAGAAAAAGAGTGATGGACGATTTATGTTTTTTTTTtCGTGATAATAAAAGGCCTGGACACCCGGGAAGGCACGCAAAGTCGGAATGCAGAGAAGATGCGTGAAGTGATGTCGTGGAAACATCGGAGCAGGAATACAAGGAGAGGAGAAGAAGACTGACCGAGTGGAAAATATATAAATCGTCGGTCGTGTGACAGAAAAAGAAAAGAGATGTTAATGAAAATTAACAAAGGCTTGCTTTCAAACGAACGTTTTTCTTGACTGTATCGCACGTACAGGACTGTAATCCAATTACGTGTCTTCATGATGCTATTTTAAAGAGATAAAAATATCAAATAATAATTTTAATAAATGAATAGAGTGCCATTTTATTACTAGCTCTTTGAGACAATTTATTGCTACTCATTAAAACAAATAATAAAAAACAATTTTtATATATATTGTAATATTATAAGGTTTTTtAATTTTAGTTGCATTAATTAATGTTATGTTAAAATTAGGCATTACATTTGTCAATGTCTAATCTTAATATAATATTAATTAAAGTAATTAAAAAGCCTATATTATATATATATACGCAAATAAAATTTATTTACATCTATTTATTTTATTATATTCATGGCTTAATATTAAATTAATGACATAATAATTATATAATTGGTTTTTtACGTTTTTTTtAAATAAAACAAACTATTTTTAATGAAATCGAGAAATTATATTCGAAAATTCAAAAATCTGAAAATGTGTAAAGATTAAAAAATCCTAATAATTGTAAAGCTCCAAGAATTAAAAGATCTAAAAATTTCAATGTCTTTATTGAGATGTTTAAATTTTAATTTTTCTATTAAATTTTTAAACGTGGGAAATTTTATGACTTTACATTCAAAAATCTTTTGTATAAATTTCATATATGAGAATTATAATTGTATGCAAAATCTATCCAGATTGTAAAAAACCATGGAATTGTTCACATCATTTATAATGTCAGCTTTGAAATCTTAATTTAAACATTTAATTAAAATATTAATTATAAATGAAAATTGATTATAAAAAATTATTGGTCCGAATAGCTAGTTTGAAAGAGTGAAATAAAAATTAAATTAAAGCGAAGTAGATTAGTACTTTTCTCGGATTACATCCCTGCACACACACGATTACACACCCATAGTTGCTGTATGTATAGTCTGCGACATGGAATGGGTCTTGACACGAATAAAATTAAACCTCGAGGACTGCTCTTAGTTTGCTCACACTCTTCTTCTTTGTTTTATCTTCTCAACAAAACTCCACCGCGAAACCGCTTCTGCATGCAAAATTAACTCTGCTTCGGTCTCCTCAACAACCGCGAGTGGAGCACGAAGGTTCCGTTAAAAAAATCCTTCAATGTGTTCCGCTGAAAAATTTAAATACCTTTAACTGAATACCTTTATTCCCGAGTTTTATCCGTGTTACTATTGTAAACAAACTGGTTAGTAAATTTTTAAAATTTTAAAGTCAAAATAATTGTAGACCAGCTACAGGAATAAATAAAACATTGATATTGCAAAGTTATTGGGAAGTTATTGTAAAAATTCGTAAAAATTTTCGTAAAAATTTTTTTTtCGAGTTTTTATAATAATTCTCTGATAGCTCTGCGATAATAAAATTTTATTGCTATATCTGCTGTACAACTATTTTGGGAATTACATATAGATTGCGGAAAAAAAAACAAGGAACGTTCGTCACCATCCGCAGGTTCAGAAATCTTTACCCCCCTCGGATTACGATGCACTGGAAACGTTAGGATTGATTTCGTATCTTTTAGGAACAAATAGCGAAGGAGAGGCAGGTGACCGGTCGCCTACAGATCCAGGTTTCGTACGAAGCGGAACGTAAAGAATTGGTCGTTTCGGTTTTTATGGCCGATGACCTGTGTACGCGAGAAGACACCGGATTCGGCATCTTGCCGGAGGCTTTCGCAAAGCTTATCCTTGCTCCGCCATCGTAAGTCCATGGACATCTCATAAATTTTCAGATTGAATATATCCGACACGTTGATCTTTCGCAAAATCGATTCTTGACCGTACTATAAAACGGTACAATGCAAAGAGAAAAAAATCCATAAATTTGACACTAAAGAAAAATTATGTGAAATTAGGACATGACAGATTGATTAATACCTAATAGAAGTTCCGTGTAAGCGCTGTTAACGCGTTTAATTGCTTTTCCAAGAGCTTCGCCAAATTGATTTCTTTTTCTTCATTTATCTTTTGTTTACTCTATGCTTCGACGGTTAAAATGAAAGGTTAATTAATCACTTGTGACCTTCGCAGCGGCGATGCAGCTCCGCTGAAAACTATCGTAGCCGAGCCGACCCAGAAACCCATCTGGAACGCTACATTGTTCTTTACTGGAGTTGATGGCGAGAGCTTGATGGAACGTGCGATCGAGGTGACTCTCTGGGATTACTGTCCCGATGGCGATAATGTGTTCCTTGGTGAATGCACTGTCGATGTTCAGCGAGCGCTTGAAAATGATAGAGCTGTTTGGTAAGTGCATTCTTTTTtTTTTTTAAGGACGGAGATCAAAAAAAACTTTTTGTGCTGAGTAACTGTAAACATAATTTGGTATGCGGTATTTGATTGTAAATCGATAAAACAATTTACAAATTTTTCCAGCTAAACTGCAAATGCTATAATACTTAACAATTATTGTAAATTGACTAGAATTAACAAGTAAGATTTTATATATGAATTATGAGATTTTTATTTCTTTCATCGTCTAAGAAGATTATGTTTTTATCATTATTAATAAAGTGCAATGTTTAATTTTCAAAAAATAAAAGAATGTTGCACAAGACCTATGTCAGTACTGACAATTTTTCTCTATTATTAATTATATTGTAAACTTGTCAACCTAATAATTTATCAAATTTTTTCATAAATAATAAATAGATTCGTAAAATGATTGATGTCGCGAGTTGTATACTAATCAAACTGATGATGATTAGCAGCAGTTGCAAAGAATCGAGGATCCGTAACGTTCGTGTATCGAAGTATCTGTAAAATGTCAGGTATCGATTGGAGGATCCACGCGGACTTCGAACAGGCAAGTCGCCGTATTGTTCACCGCGGGGCTCGGTATCGATGGACGTCGCCCAAAGATTATTCAGGAAAGAGCTGCGGGATCGTAGCTACAGCGACGATACGCAGAGCGACAGCGGCAGCCCCGAGTTCTGTTTCCTACATCCGGATCATGCTTGGCACAATTCTAGACGTGGTTCCAGTCAGTCCGAGCAACTCGAGGTTGAGCCTTACGAGCTCAACCGGGATTACAGCAGATCCCTGCCGGGTAGCCGCAGGAGCAGCTTCCAGAGTCAGGGCGGCACTGATAGCAAGCGTGAGTGTCAGGCACGAAAAGATTCTGCACGGTCCAGCTTCTCCTTTCGAGAAATCGCTAATGGAAATGCAACCACGCGTCAGTAAGAGGATCCTCCTCAAGTAATTTCCATTAGTCTCTCGGGAGTGAGAAATTAATGTGAGGCTTAATTACGAGAATATTTAATATTATAGCAGGGTAGAATTTTAATCACAATGAAATGATATCTGATGAATAAAAGTCATATCGAGCCCCTTTTACGATGAGATTTAAGAAAATTTTAACTTTTAATTTTACTCTGACTAATTCTTAATATGTAGCCATATAATGCAAAATTAAGAGATGTAATAAGTAGAGAAAAGATATCGGATAAATTCTTTTTTTTTtATTGTGTGAAATAATCTAAACTTAAAATTTATCAGACATGAGCTGTTAGCAAATCGCCATGATACAGTGTTTTTAATTTAATTTTGTGATTTTAAACGCATTTGCACAAATGTGACGCACTAACAATCAATAGAGATGAATGAAATTCTTGGACGCTGGAACTTTGGAAATTTAGCTTCTGAAAGATGTTTTTGTCGAAATTTTCGATATCGTACATGGAATTTCGACCCAATAAACTATGTTCCGTTCTCCGCTGCTGGCTACCATCCTCAAGCAAACTCTCCCTTCTTCTGTTCCTTTTCAAAGATGATAGAGTGGGACTATCCGTGATGCTATTGTTGGGTAACCTCGAGTGCTGCTTGGAAGCACTTGGCACGCTTAAGTAACAGCTTCCTCGATTATCGCTATTCGATTACGTCACTTCAGCTAGAAGACGCTCATGTAAACGTTGTAAACAACGGGAATCGATGCACCGCGAAGTATCGTGAAAAATAGCAAGCATCAAAGAAGCATTAGAGAAGCAAAAGGATAATATCATAaCATTCTTTCTTCTTTTAATGAAAACACATATATAACAATTTACAATCTAGTTATTTAACAATTCCGAGCAATTGTGAACTTTCAGAGTTGAATATCTGTAAGTCAGAGTTTTATGAGTTAAAAGTTGAAATGTTTCGTTGTCATCGGATGTTATCATTCTTAGATGTCGCTAATTGTATCTAATCGCTCCTATTTAATTCATCGCAGGTGGAAGCATGTGCGAAGCCGATATGCCCGTGTACTACAATCGCGATCGGCGGCGAAGCTCGTTCACCAGACCGATGAGGGATCCGGAGGAGATCCTGGAGGGTCTACGAGCGTTGAAGGCGACCAAGGGCGAGCTTAATAGGACCATGAGCCTCTCCGGCGACAAGAGACGCGGCAGCCGTGAGTATAAAAaTTTtCCTTGCTTTCTCTCTTTtAGCCATCATTTCGCTCGTTCGTTCGTCCGTCGTCCGTCTGATTGTTTGTACCTTTTTGtACCTCTCCATTCGTCACCACACCTCCACGACCATTTTTACTGCATTTTGTGATACACTTTTCCtCTTTTtCTATCTTTCTCTTTTTATCACCGTTACTGTTGTTTAACGTCTTGTTGGTAACCATCACCGCCACCATCACCGTCTCGTTCGACCAAGAGAGACTCATTAATAAACGTCACATCATAATCGTGCATCCAGATGTAAGTGTGCGAGTGCGCGTGTGCATTGTGTCTGGGTGTTCGTGCACCGTCTCACATGTGGTTGTCCCACCATATTCGTTACGTGTCTACATTACACGAGTCACCTGCCTGTTTCTTTCTCTTTGTTAATGTTATTTTTTtCTTtCTGTCCCTTATCTTCGATTTTTATTAGAAAACAGTTTTCGCACAGAAAACTAAATTTCATGAACTTGCTAAACGTTCTACCCGAATTCTGAAAACCATTCTTGTTTTCGAATTGATGTAAAGCAAAAGAATTTGAAAATTTGACAGTAAATAGAAAAATTAATAAAATAGAAAATAAATGATTAAAGATGTACTATTAGACATTATATTTTCCATTAAGAACAGATCTCATTTTAACGTAAAATTAATTAATACTAATACAATAACTTGATAAAATGTAAATCTTTGAAAAAATTTCGAAAATATTTCTTATTTTTATTCTTGCGTCTATACTATTTGTTATATGACACGAAGTAGCAGGACACTTCCGCAACAATTATCTCCTTGACGTATAACTTCAGTGCCAATGTTATTTACAAAATTTTTtAaCTTTTTTTtAAAAAAAaTTATTTATATAGTATATAATTTAGTTTTATATATGTAATGAATATTATTTTGTAATCACATTCCTAGTCATACTTAATGTAGCCCCCACCTATATGCTCAGCCTCACATCGTATAACATTTTTCTAGAAAATTAAAAATCTTTCTTTCTAATTTTCCAATATTTTTGTATTCGAATGTCGATGCAATTATTATTTATCTGTCTCGCACTATCATGTCCTGTCGATCCCGCGCGGCTTGACCGAGCGAACGATTTTCACACACAAAGGAGTCTCTCACTCGTTTGTCAAAAACCATGATTTCGTCCCAGTTTACGGAATCTAAATCGGACGGATCAAAGTGGGAATAGCCCGACCTGGAAAGGATTTTGACAAGACTTCGGGATACACGATCGGTTTGATTATATAGATTTTCGTGTCTAATGTCGACCATGACGATGACCGCCTTCGATACTTGCATTCTCAATTGTGCCTCATCGTCGCTTATCTCATCACACGTTCGATGTTCGGCGTTTTACCTCGTTTCTGGATTAGACTGCAAATCTCCAACGAGCATTCGCCAAAAGAAATCGTCACAACCGATTTTTCGCCACATTCACCGAACTGCGCGGTACCGATTCGTCGGCGTCGGAATGGAATCGAACCAGAGAATCAAAAGTAGAAAGCATCCCGATCATCGCCGTGGAGCGTTCATCGTGCGACATTTCGCTTGGGTCTGCGAAATTTCAAGCTTCGCCGGTCAATCATCCTCTGCTTTTTCGTCTCGAGGAGTCATCGTCCCGGTCGACCCGGAAATGCTCGAATTGGCGTGGTTTCACCGAGCATCAAACCACCACCGTTCATCCCGCCACTGTGTCTGTCTCTCGCTCTGCTTATGTTCTACGAAGAGGTCGATGTTCTCCACCAAAACCAGCCAAAGATAACGCGACCACGATCTGTACTCTCTGCTCATCTGTATTTGCGATTCGTTGTTGCGCGCCGCTGTTGCCTGTTGCTGATTGCTCGTATCGTCTCACAGCCTGACAGTAACGATTTGGATCCTTGCTCTCGCCCTGTGCCTCAGGCTTTTACGAAGCGAGAAACAGTATCGTTCCCTCCGCCGCCATCGCCGCCGCCGCCGCTGCTGCTGTCGCCGTCGTCAATGTGATCACAATAGCGGAAGACATAATTCGCTGTTGTGCTTCTGTGCCGTTGCACGCACGTGTGTGATGATTTTACGCGCTACGATCTTCCGCTCTTTGTTGCTCTCTTTCTTTCTATCTCTGTCTGTTCTTATGCTATTCGGCCTCTCATCCACTCCGCCGAGTGTTGTTTGACACCAAGCGCTCCGCGTGCCATAAGCGATGCGCTGCTCTGATCGTTCTATCAGCAAGATTATCGTCTCTTCGTTTTtCAGGCTTAATGGTCGCTTCAGCTAGCGGCTTTTGACACATGTTGAACGTACGAAGACGATATAGATGATACGTTAACAGTCATAAAAATATTTTGTATATCATTCAAGAAACTGATGCTCGAAGCAATTATCCGATAAGCGCTACAATATTATTTAATATTATATTAATATTAAATAATATCTCTAAAATATTAATAAAAACTAGTTATACGTCCACTTCTGATAATATTATATGAATGTTATATGAGGATTAAATAATATTATTTACTTTAATATTTCAAATTTGAAAATAACTTTTAAATGTAATAATTATAAAGTTTATGAATATTTTATGCATAATAATTCACATTAATTTTTGATCACAATAATATTCGTAGAACATTTTCGTAATATTCCACGGATATTGAAATAATATACCACAAATATTATGTAAAAACGAGCGTATAACATTGCTACAATACTCCCGTGATATTAAAATAATATTAAAAATATTGAATAATAATATTCGTATAATATTCGTACAATATTCTAGGAATATTGTGTACTATAGGATAGTGGCAATATTGCTTTTCGTATCCAGTTTTTACCATTTTTGCAATATTATGCTTTGCAGTACATTCCGCTAAAATATATTGATTTTTTAAACGTATAAAGAAGAAGTTAATTTTTTTATTTAGTTTAACGCGAAATTATCGTCATTTTTATCTGCTGACGGCTAATGAAGACAGTAAATTTGCAAGGAAGTAGACTCTGAATTGTGCATGAGAAAGAGACTGGCTAATGTGTTTGGAGCACGTATGAAAACAATGAATTCAACGCAATGGGTCAAAGTGCTCCTCACGATTATCCCTGTCAAGTCTCCTCGCTTTCGCTCGAAACAGTCGAATTTGTGAAGCATCCCTCTCGTCGCTACGTTGAACATTCGAAGCGATCATTAAGCGTCCCGACGTTACTAAAAGAATCGCAAAATATCACCAATATCAATTTCTCGCCATCCGACTTCCTGTTGACATCTGTGTGCATCTTCGTTCACATAAGTGCACGGCCTCGAGCGCAGCGTGCACTTTTGAAATTTTGACGCCTCACTGTATTGTTGATTATCTTGATATCCTTTCTCGGTCGGCACCGTCCGCCAATGCCAAAACTCTGAACGCTCTTCGTACTCAACTCGAATCGCGAAACACTCGGTTCGCTCGGTCGAAACGCCATCGGCCATCGTCACGACCCCGATTATCGACGACAAATCGTGGGCCACGCACGCACGACCAACCAACCAACCAACCAACCAACCAACCAACCAATCAACCAACCACCAACCAACCACCAATCGACCACCATCGACCACCAACAACGACAACAGAGTGCGTAGTCCCAACAGTTACTGTGTGGCAGTGCGAGCCTGTGTCTCCGAGGACCGGTAACTCGGCCTCCTTCCCATTGCCGCACTCCACACCACCTCGATAAATAATCGCAAGGCACTGTCAACCAACGTTACGGGCTTCCGGTAAGACACACTCTTTCTCTATCGCTCTTTTCCTCTACCACTCTCTCTCTGTCTATCTGTACTTTGAGCAGAATCTCGCTTCCAACTTTTGCCTCTTTTAGTTTACCCTCAACAAACGATATCGTAGCATTTGTTCTGCAACGATGAGAGAATAAGAACGGACTAGGTTTAACGATGTAACAAACGTAGATGTGTAGCTAAACTATTGAATATCCGTTAGAATATTAATTAGTCCATTAGATATCCATTAGTTTGAACGTTAGTTCGAAATAGACGAAACTAGAAACGGATCAAAAATAGAAATAGGATTTGGATTTGAATACGCCCAAATCTGATTGAATTCCTGGATTACAGCTTTAAATTTCATAAATTTTAATTCTCACAAACATATTCATTCACGAAATTTTAATGTACATTTAAAAAGAAAACAACTCTATGTCAAACATTAATTCCATTAGTGATATCACGTTTTATTCGGCATTGAAATCGGTAATAAATATTCTATTTTATTTGAAAATGTTTTGTTTTTTTtCATAATTGTTCTTTTTtACAAGTAATCATAATAGAAAAGATCTCTACAAAATTTATATGGTAAATAAAATTTTTATAATTATTAAAAATAGATAAATAAATTTCTCTCTCTCTCTCtcNNNNNNNNNNNNNNNNNNNNTTAATTTAATTAATTAATAAATAaGATAATAAaTTAcTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCTCTCTCTGTTTATCGTATGTCACGTTTATTGAACATATTTTTTtGACACATGTTGAACGTACAAAGACAATATAGATGATACGTTAACAGTCATAAAAATATTTTGTATATCATTCAAAAAATATTTTTTCTCTGCAATCTTATTTTCTTCATTCATCTTTGTGGGGATCTTACTCAACTTTTTACTTAATCAAAAAGGTAAACGAGATGCTACACGAAAAGGGAATTTGAAAGAGGTACACATCATTATACTGTTGATAGAGAATACCGTTCTAATATCTCTCATGTTTCGCTTCTTTATTTTTGCACTTTTTTTCTCTCCCTTTGCGCGCACGTGCCATTAATTTGTCTTTCCCCCGATACACGCTACATTGTATTTTTCAAAAACGCACGCAACGCCATTTATCATAAGACAAGGAAAAGATAACATGTCGGTAAACTTCACCCGCGGAATATTTTCTTCCCCTTTTGCACGCGTCTTTCGTGATCCCATCGTGATATAATTTTTTATACATCGAGATTAATTATACTTCTGTTAGTTTTGCAACTTCTCGGGTATATCATTAATTTCCTGCTTGCGTTAATCGTACTCCATTTCATCTTCTGCTCTCATTTATTAGTCCAGTTAATCATTCTAAAGGCCAAGAGTTAGTGCGTTAATTCTTTGCCACGATTTAACTTCATCCCTTTCTCTCTCTCTTTTTTCCACGATTATATCTCTTGTTGAATTTGAGCGAGACAACCATTTAAAAATAATATACTCGATATTTTCCCGGGAATTGCTTTTATTATTCTATTTGACTTTGTTAATTATCAAAATTTCTTGAGCAAATTCAGTTTAATTAGCGGTTATAACTTCATTAACATATCCTAATGGTTTCGCCGAAATACACGTCTACATCAACTTTGCATCTTGAGTTATTTTAACGTTAACAACTTTACGCATAACTTTCATAACTGGATGGAAAAATGAATAAATTTACAATTAATAGAGAGCACTTACACACATATACCCATACACGTTTGCTCGCGCAAACGTTATTTATTTATTTAATAATACATTGCGGAAATAGTGCAATTTTTCGAGTCATCTGCATATAGGTGAGTAGCAAACAAAATTCCCTTATCTTCGTTCCTTTCCTCATTGCAAGCCTTTACGACTTCCTTTTTGCTTCTCTTTCCTAAATTTTCTTGCAATTAGAGCGAATAGCGCATTGATATATTTGTTTCAGCGCACTATTAGTTTATAGATAATTTGAACGCTAGCCACTTACTGCTACCACTGTTGCTATCCACACAATCGTGATCTTAGGTAAGAAGTCGAATGCCATCGTCGTATTGTCGCACGTCTTTAGAACTGTATATTGACATGTATATATGACAAGTAGTATTTTATTAATATGATTGACTTATCTAACAAAATGTCTCTATACTGATTATATGACATATTTCTACCAATTCTTTAAGTATATCTATTGATATTATGCGCCTGATTTAGAAATTGTTAATCTTTTTtATTTTTTACTTTTAAATATTTTTTTATTATTCTTTTCTATATTTAAGTTATTTTATTTTATAATAAAAATATATGTTAATAAAAaTATATGTTATATCAAGGAATATTTCTATATTTGTATATTTTGTAGAAAAATATTTTTATTCATAAAATGATAATGTACAATGGATAAAAAAGTATTTTTATTGATTTTTTTtATAAGAAATTTTTTTtATACAAGAATTAAAAATAAAAAGTATAATACAAAAAAAGTGGAATGTACATATTGATATGTACATATATGTAAATAGAGCAATGTGCTAATAGATATATGAATGAAGAATACGTTATTTACGCCAAGTAAACCTTTGGTTTTATTGAAAAAAaTTAAAAACAAATTGGTAGAACTTGTAATTCTAAATATGTTATGTTTAATAAGTAATTAAATTATCTAGACTATCTAGAGAGTTATAATGTTCATAAAAAAAGTATTTGCTAGATTATTGAAATGATGTATGCGGGTGTCCTATAACAAATAATAAGGAAGTGTAAGAATTATAATGAGAACTTTAGAAGGAATATGTTAACAATAGAACAAGAACTATTAGCTCCCCGAGCTTCTAATTATCTTATTACAGCTATCGAGACCGAACTTCCCTCTTCGTAGAGTTGAAACTCCCTGCTATCGTTGGTACTTTGGAGCCGAAGTTTGTATCTTACTTCTGTGTAGAGAACGCGTTTGGAATTTATTACATACATCTACGTAATTCAGGAAGCTTCGGTCGTTGAATTTCACGATTCGGTTAGCAGTTCCATTGCCGTTGATTGAATTGCTTGCATAGAAATACCTACTACATATTCTTGCACAATAAAGTCGACGTTATCAGCAATTTAAAAATTGACAATAGTACGACACGGTGATATGTTGATTTACTTTATTTGTTTATTTTGAATTGTAAAAGTGACATGTACGCAAATATAATCTCTTCCTGCTTTTCTTTTACTATTGTGAGTGATTTTAATATACGATCAAATATTTTATTTAGTACTTTTACAATTGCTTATTCGAAGTACCACTTAAATAAGACGATCAACATAACGCGTTCACAGGACTTTTGAAGCAAACGTTAAGAAAACTGTTACGTTAACAATACAATATCATTTATTAGAATCATAATGAAATTCACACGACCGAAGATGCTTTGCAGCTGTCGTATTGTTGAGTAGGAAGCTTCTCTGAGAGATTTGTTGCAAAACTGAGTTTGAAATTACAAGCCCGTAGCACTAACTCTTCTGACTGGCAGGTGTAAATTATTTGATTCAATTACAACTTAACTGCAACCTGTATGGAAATACGGTACTTGGAAAATCATCTAAAACTAGGAATGTCAATTGTATAACATGTTAATATTTTCGAGCATGGTTATTCGGTGAATAAATAACATCTTGATAAAATAGATGTCTGCTTGCTCGCGCGATGCCATACAGTTTGCAGCTGATCCGACGTGATCAGTAGTGTAAGAAGATATTTTTCAATTTGTAGGGCGGGGTGAGCGCAAAGACAGCGTCATGGAGATTCCTGAGAGATTTTACGATCGAAATAGCGAATCCGACGAAGACGAGAAATGGAGGTACGCGATCCATCTTGAGTGACAAGTTAAAATGGATCAATCACTCCATTCTATTCACATTTTCGACGTATTTATTATTGATTCATCAATTATGCTTTATATCATCGCGTCGTTAATATTTTACTTTAGTCACAGCGATGAGGAGAGCGCGGAAACTCCAAATCATCCTACATTGATATTCATTAAGCTAAACGTAATTGAATTTTATGACATAACTTTTGTTATTGCAGTCAGTCGGCGAGAAATGAAAATGGCGTCGATCTGAAACTGGGTCGTGGACAATTGTTGCCGAAAGGAAAAATAATCAGTGGTAAAATATTCGTTCCAGCCTTATGAGCTCCTTAATTGGTCTTCTAAAATTAAATTATTTGTTTTCGCAGATTTTTATGTTTCATCCTGGTTCCTCTAAAGATTATATAATTTTCAGTGACTCCAGAAAGTTATTTCCATAATTACACTTAACTACTATAATTTTATTACTATAATTTTATTACTATAATTAATAAATTGCAGATCTAAAGCCGCATTTATTTTTGATCCATTAATGTTCATTTCTACCTAAAGTATTATAGATTAACTTTGGCCTCGCTTTAACTCACTCTCCACCCTTTTCTCATTCTTAAGTTAAACCGAGATCAAAGTTAGTTTTGTACATCGATGGAAGCTCCGGCATAAATCCTCTCGAATATTCATTAATTTCGATTCCATTAAAATTTTTTCTCGTTACAATTTTGCTTTTGCACTCGCTTGATTGCGATCGCAAACATTGCAGGAGCGCAGAACGGCGAAGTGCAACTGGGCTTCTATATGTGCAAGGGAACTCTCGAGGTCGAAGTTATCTGCGCAAGGGACATTTGTCCCGAGGAGAAGGAGGAGCCAGGTAATTTGAGGAGCGTGCCTTTGCCGCTGTTAATTTCCCCCATTCGAGTTATTCGTTCCTGTTTGCAGTTACTATAAAATTCTCGCAACGTCGTACCTTTGAGAGCCTCCCGGCCATTTATCCTCGCGCGAGCGTTAATTCCGTAGTTGTTACTTTTACAGCGTGCGGGCGTTCGGTCTTGATTATTCATGCATTACTTTAGCGTTTAGAAACAAATTTCCGCGCGGGCGTTCAACGCGCCGGTTAATCGCAACGACCTACATCCGCTAACTCGTTAAAGGCTTATTAAGGTCGACAGTGAAGCGAAGCTAACTAAAATATTTACTTTTACGAATATTTTAGACGTAATGTAAAATAATAAACGAAGCTATTGGCTCGGTCTTTTTATATTTTAATTTGGTAAAAAAAGAATATTTAATAAGACTTGCGACAATAATACATCTTAACTTATCTTCTTCAACCGTTTCTATTTTTGCGCATTATAAAAGATCGAATGTCTCTTTGATCCATGTCTTCAATTGAAAATTTCCAGGAGAAGAAAATTCTCTCCACTTCCGCAGATACCTTAAAAATAAACCAGATTTAAAATAAACTATTTTCCCGAGTACCGTCGGTAAAATGTTTATCCTTATCCGCAGATACTTACGTGAAGACGTACTTGCGAGAACGAGACGGCGAGAAGTGGCTGCAGAAGCGCAAGACCCGCGTGGTGCGACACTCGAAGACCCCGCAGTATCGGCAGACGCTGAAATACGTACGCTGCGACACCCTGCAGGGCAGGCACTTGCTGGTGATGCTGTGGGAAAAGAAGCAGGGCTTCGAGAGCAACCAGGGGCTGGGTGGCGCCGAAGTGGATCTCGATGTACTGCCGCCGAAGGAATTCATCTTCGACTGGTATCCGCTCTTCCCGATCCACACCCTCGGCACGAACAACGCGGACTCGCCATGATGGCTAAGGGAAAAATGGGCCCTCGAGGCCGGCGAGCTCGACCTCAGATTGAGCCTTTTGCTCAAGGACGAGGGCGAGTCCGTCGTCAAGATCATCTCTTGATGGAAATCGTGGCTGATCATGTGGCAATTTCGACTGGCTCGAATCGAACGCGATCTCGAACTCCGCGCGACAACGGCATTCTTTATTATTGCAAGTCCTTGAGAGTAGCGACGAGGCTCACGTTGTTGCCCAGAATGCAAATGAAGTTCGCGTCGACAAGGTTTAGTTTTTTTTTTtGCTACAACTTTTTAATCATAACTTGTAGCAAATTTGGTTGGATCGCACTGGTACGTACTGGTGCACATTAAAGTCGCTGTACACTGATCTAACCTTGTTTAAGAATAAAAAATAAATATTGTAAATGATGAAATATATATTTTACTAAATAGTATAATAAAATATCGATTGATCGGGTTTTCACAATTTTATCTGTTTATATTAAATACGTATTTTTACGTCGATTTGTGTACGACAATTTTAATGTGCATCAGTGCTCACTAGTCCAACCGAATTCGCTATTATATTCACAATAATATACGGATGTGTTTGGATGATGTTCAGAATAACACATTTATTTtATTCAATTGATCTATCAAATTACATTGTACACGAATATTAAATATTAAGCGCATCCAATGCTGATATTAACGTCCATTAACGTATTTTATAATTGTTACTTAATCAATCTGAAAGTGCAAACAAATAAGTAATGAACACATCTGTCAGTTGTCAGAATGTTCGGTTTATTTATTAACATTTGCAAATACAAATGATCGTGGAAAGGAGTATTTCTAAAATTGGATATTATCGAAATTTTATAATAAAAGGATATGTCTTTTTTtCTTTTAATAAACATAAAGTTAAAATGTCATGGAGCGTAAGAACTTCAGATTGCATCGCAATGTATAAAAAGTAATTCTCAAAAaTAAAAaGATTAGTCAGTAACGTGGATCGATCATACGTCGTACGACAGACTTGATTGAAAAAAAAAAaTGCTTAGCGTATAACCGGAAGACAATCAACTTCAGAGGGTTTATACAATTGTTCAATAAGACAATCAACTTTAAAAATTGTAAAGACAATGAAGCTTCCATTGAACTTACACTTGTGAGCGTCAGCGTCAGCGTCGTCGCGTTTCAACTCGGTAGTAAAAAAGGAAGTAAAAAAAAaGAATAGAAAAGATGAGAAAGACAGATTCAAGAGAACCGAGTTCCTTCGATTAGCGCCTTTCGAGATCCACGAGTGCCGATGAAGCGCTCGCGGTGATTTTAGCAATAAAGGTGTACCTGTGAAAGTCTTGTTTGCACGAAGCGGCAGGAACAAAGAATGAAAAAGGTACGGAGAGTTTATTTTtCGACGAGCAACTACAGAGACAAGTGGAGGCAGCCATATATCCTGATGAAATGATAAGGGTCCATTTTTCCCGAAACAAATATAATGATCGACGAGTGAGTATCGTCGACTGTGCGAAGCGAAACTTGATCGACATCTGCCGCCGGCGGTGGTTAAATCTGGTTGATCCAGTCAGTGATTCGATTGAATTTCGCACGTACTAATTCAAATATCGATACTTAAGGGTCAATATAGGAGGATGTAGACCCCTCCTATCTGATCCTTCTACGCCGACGAGGCGCTTTCGGGATTCGCGTTTCTATTTAAAGTAGATATTCGATTGAGAATGTAGAACTTAAAATTTGCAGTAATATAGTAAATTATTGTAATCCTTTTAATCTATTAATTTTTCAAAATGTATTCTTTTGCCGTGCTCTTACATTAAATTTATTATTGTATAAATTTATATTAATTTGTACAGAACATAATTTCAAATTATTTTTTTTAGAATTtCTTTTTTGTATAAATAGCTAAAAAAAAAaTGATTTATGAAAAAACGGAAAACAGTCGAATCAAATGGAACGCCTCGGTCGGCGTGACTAAATAATGCTTTAACTATTTAATGATAGACAATCGTTTCAAGGCTTGCTGGCCGAGCCGATGACATAAAAAGACGAGTAATTAGCTTGAGGTGGTGGCGAGATGAGCGGATGAGTTCCCGGAGGTAAACTTCGCGGCCAACTTGAATAATACCCAACCAAACTCGGTGTTTAGAAGTCGCACAATTTTTGTAGCTCGTAGACTGATAGCGGGACGTCGAGGCGGACTTCTTTGACGTTTCTCAGATGTAATACTGACGTCCCGTTTTGCGTAGCGTCTCGAAGATCACTATGACCTCATGAAGCAAGTTCGATTGGCCATAAAAAGAAAAAAAAGAAAAAAAaTCGACAGAAACAACATAGGAAGAGATATGCGAAAATTCCAATGCGAGCTTAATTCATCACTTCGGGATGATTCACGATGATCCTCGGGACGCGTTAATGTGAATGTTTAAATCCTATGATGTCCCGCGACGAGATTAGGGACATAATGGATTGTCCAGAATTATTGCGCTTACCCCGCCCGAGTAATTAGTAATAGGTAATGAACGTGATAATATTAATTAATGATTCAGCAGCATTCTCACGATATGATCCATAAATTTATTATTACGCTGAGTGTGATGCGTGCACAGACGGAGAAACACGCGGCGGTACTTAAGTGATGTGGTGTATCGTGTATAACGTGAGGCTCACGGCGGGTCGGTATCGACCCCCGGGACTTGGTATACACGTGCACATCTATATAAATATATATATTATATATTATTGCAATCCGCGGGGAAAACTGTAACGAAGGATAATCAAAATGTACATGTGTTTAACCGGTACGATTAAGGATAAATACGGTGTCACTGTCCCATATCATTAAAACTCGGTGTTAACGATGTAGATGTTTAAGGGATGTCAACGAAAGTTCGGTCGAAAATTTATTTTTGCGAAGTTCTTTGAAAAAAaCAAAAAGAGAAAAAAaCGAAATTCTTAACGACGGTACATAGGTAGGCGGCTCTTACATTGGTAATGTCGTTTCTTCTGTACGTAAGTTTACGTTGATTCTACCTTTTTAAATATTAGATCTCTTGCAAAATATCAGATTCTCTGACTTTTCTTACGGAAACTTTTACGTATTCATTATTCACGTCGGATCTTTAAGATCCAACGGTTTGGACAAATCTTGCGATTCCTTTGAGGATTCCTTAATTGGCAATCTGTAAACGGCAGACTTTTGATCGGAAAGGCATGCACAGGCGGAATCGCGAGCGCCCAAGCATTCAGAAGAAAGTAATTTTTTTACTTAAAGCACACGGAGCGGAAAAGCATATCGGCCCGAAAAAAAACAAAAATGAAGAAAAAAATGACTCTTTAATTACGGTTGTGCTGTTCAGACACACATACACACACAAACATCTTTTATCGATATAATCGCTACATCAGTCTCTCGCCTCGAACGCCAGCGACACGCCTCGCAAGACTCATAAACGAGACGATTGTGCCTTTGCGAGGGCTACGTCAGATATATCGTAGAAAAAAAACAGTGTTTTACGAGCAATCGGCCTAGAAACATATCCGATGATCATGAATATTAAACAATACAGATTCGAACTTTGCTGTAAAACAAATTACTTCTTGTGATCTCGTTATATGCTTATATTTATAATATGTAATACGTTACGTAGTACTCGTATCGTGATCTTAACGATATTACGCACATTTACCAAAGTCGTTAATATTTTAATTAACGTGCAGCTTGTAATGTAAATTAAATTTCGAAAATTTTAAATATTAATTCTTTACTTTACGAACGATAAGTTATACGAATTACGCGAAAGAAACAAGGAAATAAATTCAAAATATGATCTTAGCAAACGACGAAAAATCGAAAGTACAAGCGAAAGAGATATTTGTAGCAAGAGGATAAAGGAAATCGGTGAAACTTTCGACGAAAAATCACGAATTAATTCGAACAGATGCATCATTTCGTCGAGGGTTTCCTCGTGTGAAGATTATCGCATGGACAATCTTCTCGTACGAATGCAATCATCTATACTTTAGACGGAGGACTTCTCTCCTTTGTAAGTAGTTGAGCGCATTCTAAACAAGTTTTCTACTAGCCTTCGAAGTGACCTAACTATTACGGACGTTATCGATGCCGTTGTTACTGCTTCTTGTTCTCCTCTCTTGACGATTCTAGATAAATTAATACTTATTAGAGCTCGAAATGAGAATTTACATTTCGTACACTGAGAAAGAAATGGTGGTTTGACTAAATTTTTCGACTCGATTGAATTTCTTCAGCTCACGTATCTATGTATAATATTTAAGATAAATGTATATGTAGTTAAGTTAAATATATAAACGCTTTATCCAAAGTTCAAGTATTTTACGTATTTAAGTCAAATACATAAATACTTGAACTAAAAAAATTTAATCGAGTTGAAAACTTTAGTCAAGTTAACAATTTTTCTTTCTCTCAGTGTAAAGGTTTTTTTAGTTTtAAATTGTAGTAATATCAGTGTTTTTTATCAGTGAAATTACAAATCACAAATTAATTTTTTTTtCTTtAAATTATTATTTGGTCATTATTTAAATCAGGCCTGTATTATTCTTTGCGTTTAAAAAATTTTTATTCTTTGCAATTCTTTTTAAACTATTACAAACTAAACACGCTCTTTCATACATTATATTTATTTATTTAAACTTAAATAGATATAAATAAAATTAAGTGTTTATAATGCAAACGTATAATTATATCTATATATTGATATTTACATCTATATGTTCAAAAGTCTCTGAAAGCGAAGGATTAAATTATCTTCGAACACGATGCTTCACTCATTTCTAGCGCGTTTCTAAAAATCTTCTAGTAGTTTTCGACGAAGTTCGAGCTTACAGTGAAACCCTTACCTTATAGTAAAATCTAGACACGTGTCATTCGCTCAGATAAAGAGCAACTACGATTTTTCTACGATACAGAACGCTAGCACCTTAATGTAGAGCATGACTTGAGTCTGTTTCACTATATTGTCTTACGTCTAATTATGACGAGCACGCACACAGACATACACACGGACACACACATACACACGAAATACACATAGAGACAGACGGACGGACAAACAGGCAAACAAATACATACGCAAAAAATATATTGTATCAATCTTGACAATCGAAACTATTGATTCAAATTTACGCTGTGGATCTCTAGAAGATAATATATACTTATTACAGTTCATACTATATACATATGTACTATGGGCCGTGTGTAAAATATTCCTAGAAACGATCGCTAATTATCGCGTAATTGTACATTCGGTACATCATATAAATTATCAGGTCAATCACAGATATAGAATTACTTTCCTCCCCTTCAAAAAAAAaTTATTGCTGAATATAGTTGAAGGAAATAGACTTTCTTCCTCTCTAGATGAATATCGACGCGATTGGTCACCTCGTTGAGAACGCTGTTAATTAAGAGTTACAAGACGGCCTGTTCCCTTACATATCTGTGTTGTACTCGTTCTAACTTCTAACTGTAAGTGTCAGGGACAATCTCACGGAAGTGCGCGCGTATCTTCACGTGGATCAAACAACAACGGCATTCTCTAGCCTGCGTAGCAGGAAGCGTGTCTCGTATCAGCGTTTCGGCGATGCAAATCGATCGCCGTTTGAGTTTCTTTAATTGCTATGTTAGTGACGCTAAGAATTTAGCGGAAGGCAAATCGCTAAATGGGCATACGATCAATCTGTTATACTTCATGACGAAACGCTGTGCGAGAAGAAAACTAGCCATCTGCCGATTGTAGTTCTCGTTCGTTTTCGTTCCTCGTATGATTGTGATCGTCCTCATTATTCCTTATTATCATTTCCAACACTTGTTCGATCATACTTTGCCACATTTCACGAGAAAGGATGTTTCGCGGGAATTTAATTAAGCGATCGGCGATAATGATGATCGCGATCTCCGTTTCTCAGCAGGGAACGCTCAAGTACGGCCTAAAATCACACATTCGAACGAGTCACGAAAGGAATGCTTGATCCTCGTAGATGCGCGATTAATTGTTACATACGTACACCTGTAAGTACTAGCCGTTAAACTGATGATTTATAAAATGTGTAATTAAAATGAAGCGCGAGAGAGAGCGGCTTCGAGAAGGAAGAGGAGAAAGGCGAAAAACGGAATCGCACGTGAAAGATTTTAAACGAGTTACAATAATCATTCGGGACCCAAACAATTTCGGCCGCAGAATTAGGGACTGGTAGTTTAAATGTGTTTAGCGATAATTAGTCTGCAAAAAATTCAATTCGACTAGAACTGATTCATCGTTAAAGAAGATATTCTCTTTAGCAGAAAGAGCTCTCGGTCTCCGCTAACTGACTTCTTCTATGACACCGTTTCGCTCGAGGCAACTCGAGATTCCATACACTAGACTAAAGCAATCGAACTGTTTTTCCAATATTCTCCGCGTTTCGTCTTTCTAATATATCGCTCTGTCGTTAGTGACTGTAGATACTAATATAAAATTAGAACTTATGAAATTAGACACGTTAAGAAATTCTGCCATTTTCTCATCAGCCATAGGGATGGCAGAAAAACGTTTCGCTGGTGTACAGTAAGCTGATTTCCTTCGATCATGACACGTATTGTGAGCCGTCAAAGTTTAGAAATTTATATACAAAATTTCATTTATGAAATTTCACCTTTTTGGATAGTGAATACATGAAGTAGCGAATACATATTGCACTAATAATAAAAATGGTTAACCGCTCTTAAATGAAAATTATATACATATATATATATATATATACATATATACTAAACTTTATTACTtATTTTGAATAATTATTTTAAATAAGAGCATTGATATTGAAGAGATACATCTATATTTACAAATCATATATATTTAATACAATCACTTCTTAAATATTATCAAGTTTAAATTATATACGTATTTAAtAATTTTAAATGACAGCTGTCACCCcTCCGACATAGCTACATAATTTTATTAATTAAATCTCTGACGTCTGTTTGAACATAATAAATATGGCTAACAACGTGTCGAGAAATACTGAAGAATATCAGCGTAAACAGAAATACACTATGGCCTTGTAAAGTCTTATATAAAAAAGGGCAAGTGTGTCGACGATTCTTCTTGCTTTGTTTTATTAGAATTATTAGAGATTAAAATTCGTATAATTTTTACGGGCGATTGCGCAATCGCTCCGCGCTCGTGCGTACTTTCACGAAAGTGATTGCTCGCAAGAAAGAGCGCAACAACGGGAAAGACACCCTTAACGTAGCTAAAAGATATAAATACGATATGTTGTCACACATATATCAAACTTAATGTGATGTTCCCTGCATGTTGAATGTTGATCGTCACGTATGTGGATTAGCGTCACCGAGTGTGATAGAATTGCGGGTTAATCAGAGTGTGGGTAATTAGCGGTTAAGTGAACTGCGATACAATTTACTTTCTATTGATTTTGTGGTAATTAGTGGTTACGAAGCAGTCTTAATTATTAATTAAACATTGATTGGTCGATGGTGATCGAGGAAATCGTTTCAGAACCAAATAAAATTTATTCTTAATATAACGTATGAGATATCTGGGTTGAATAAAAGCCACTTGATTCCTTTTATTTTTCAAAAACTCTATGGATATTAAAATATAATGTATTTCAATATATATTTCCATAAATAAACTGAGGATATTGAAATAAAGTGTATTTTAATATCCTCATAGTTTAAGCCCATCTTGTATGCATAAATTTATATTAATTTAAAGTTTTAATTTTATAAAAAAAAaGCTCCGTTAAATAAACAAGATATTTTAATTCTGATTGGTTACAAACGGTTTTTTAGAAATTTTTGATAATATTTAACAAAATATTTGAGAGTAATTATTAATATTTTTTGTTTATAAAGTTTGAAAAAAATAATTTGAATATTGTCCTAAGAACTTCTTGTAATCGATGAATCAAAGTTTATATAATAATTAGTAAATTTATTTAATTTTAATCAATTAAAAGAGTCTCGCTCCTCAATTTCAGGAACAAAAACTACGAAAGTATCTAATATGACTTCTACAATTTTTTTACAAGGAAAGTTCTCTGAGAGACAGTAAAAAAAATGGAATTTTCTATATATTTAAAGATATTTTGCGGATATTAGCAGCGTGTCTTAAGATAGCTACCATGTCTATCTAAAAATCTTATTTTGTTCTCAAACACGTGTGTTTTGTATTTAATCTGTCTATTGTGTAATGATGAAATGTCGAGCATTACTAATTTCTAATCGTGGATCGATGATAAATAGAATAAAAATAAGGCGAGAATAATAAAGAAAAGAAGAAGGCAATGTAATTAAATAATAACGTAGCAATTAGAATAGACATTATTATTCTTCAGTGGAGAAATGTATTTTTCCATATGTCAGAAGAGAGAGAGAGAGAGAGAGAGAAAGAGAGAGCAAGCGTTCCATTATAGTACAATATTGTATGTAATATTTTTCTTGAGAAAGTACAGGAAGGACCATCATATATCTTGCAAGAATGCAAATAGTTTCGATTAGTCAGCGATTAAATTAGAACAATAGGTAGATTGTTGATAAGGTTAGCGCAGTATGCTTCGTATTTCAGAATTAATTTTTCGAAGATTAAAAATCGACTGCTGCGTTCGGTCGTGCTAAGAATGACGTGCAAAAAAAAaCAGGTGATATGAAAAGATATATAAAGATAAGGAGTGCCAGATTGACAAAATGTATAGAATGTATAGATTGACAAAATGTACAGTGGCTTTATACATCCATAACAGAAAGGTACAAAAAGACGAAGCCTCAGCCGATTTCCGTTTGCTCCTCGTTAAAATTTTGACGACGGTATACAAGTCGCAAATTTTTTACATTAAAATTTGTCTTCCTAAGAATTTTGACCGTATTATTGTCTTCTGTTTAATTGATATTAAATTTTAATTTAACATCAGTTGAGTGATATTAAAATTTAATAAGTTACTTCCTTGCTTTTATGCATACGAGTGCTTGTGCAGCAAATGGTACCAGTAAAATACAGTTGTGTATGCGGTCTGTAGACTAAAGTCTGTGCTGGAAACGAAAAATTCAAATACTTACTGTGTAATAAGTCTAAATTATGCAAAAATATCTCATAGCTTGATTCGCGAAGCGACGATTGAGCTTTTTTTTACATTTGTCTCTTTCCTTTCTTCCCACCTAACATCTGAATACGCTTACTTCATTTGAGATGCAAAAGGCACAGAGAGACGATTAGGTCTAATGTCGACGACAAACTTGAGGGATGACTGATTTGTAGTATGTATAATATGCGTATGTGTGTAAGTGTGCGTCTATATGTAAGGCTTTTGAGTTGTTCATCCATCTACTTTTCCTCGAGAAATTTATGGATTTATGTAAATCCCTTCCATTTTACATTAACCACTTTTCCCACCACACACGTGCAGCACGTATGCAGACACACCACAGACACATGTACACACGCATGTACACACCCACGTCATGTACGAAAGAAATGCTGCATATATAAAACAAACGTTAGATAATTAATGATGTGAAAAAAAAGCGAGATCAAATTGCTGCTCGTTCCTGTAATTATCAGAGACATGTTTTGTTCTCATGTAAAGCACACACACCGAAATAATAAATAATATTTTTTGTCGACGTAATTTATCTTAATTTATCTTCATTTCCTCGTCCGTCCGTAAGAGAAAACGAACGAAAAAGATTCAAAACTGCAAGTAACTTAGGTAACTCATCTAAATTAAATAAAATGACAAATCCATTTAATGCCAACTCTTTTATTCACTCAGAAATTCACACGACTTATAACAATACACAAATATTATATTAAATAAGTTATATTTATATTGTTTATTTAAATATTATAAATAATTATGGTCTTATCTATACTATCAAAAGCATTTACTTTTAGCAACAGCTAAAGAATTTTCAGTGAAACTTTTACAATTTTGACAGTTTTTTAATTCTTTACAATAAATTAAATTATTACTATAATTAAAACGTATGGTAAATATTTCTTTTTTAAAAAAaTTTTATATAACTTAAACGCAATTGTGAATAAGATATTCTATTATAAAATTCTACATTACCTACGATAAATAATGAATATTTGCAGTATTTAGTGTTCTTGTAATTATATGACAACAAATTACACAATGTACAAAGAAGACCATTAAAATCGTAAACAATAAATTAAATTTCACAAAATTATTATAACTTAATGAAAAATTTCCAATTTGCACAAATTCACAGATTTTTTTTTATAGAGTCGTATATACAGTATCATTTTTTTATTCATCTTTCCGTTGTATTTACAAATTCAGAATTTATCCATTAATTACTAAATTTAAAATTTATTTGAACAACACAATGTGTTTTTCTTGATATATGACCGTTAAGATTTGTATGTCCTGTCCCTTCCTATTATGTTTGGGAGGAAAACACGTTCCTGCCGGCAACGTGTTTCATTACAGTTACCAATCTCGCACGTGTTCTGCGAAAGGATAACATCTCTCTCTAATTTGGAAAAGTAATTAAGATTTAAACAATCTCTCTGCAACTGCAATCATCTCACAGCATGTTTTTGCAGTAAGTACCATCATGTATGTACATACGTCCGTGTATGACGTTCAAGCGTATATCTAATATTCCTTTCACCACGTTAAAACATGTTACCGAGATACGTAAAATGACCTGAGAAGTAAATGTCATGTCAAGTCATCAGTAGCCTATCATTAAAAGACGTTTTAAATATATTCACATCGTGTACTTTTAATAACGTTAGAATAAATTTAAATTATATTATGTAAATTATAAATACTTATCATTCTACCTTTCTTCTTTCTCTGCAAATGTGATTACGTCAGTAACGGTTCATCTCTATTGAAGGAAAAAGAGGAGAAAAAAGAATCGACACACACATAAAACATGGCTTCTTTGTGAAATTCATATAAAATTTTATTTTTATTGCAAGGCAGTTTGCAGAAATAAATGTGTTAATTAAAATTTTAAATAAACTAATATCCCGACAAAGCTTTTGATAAAAACAATTTGTTCAGTTTTATATTTTTATGTTAAAAGAAGTCTATTTTATTTATTAAAGTCTATTTATTAAAGTTTATAACGTCACTTACAAGTTATGTAAAAAATCTATTTCTTCAGTAAATTTTTAATATGACACATTTCGAAATAATTACATATATATGTATATATGTATATATTTTTATAATATTTTAGATTTATTCTTGTTTATGCATATATCACATTATTAATCACGTTATTACTATTCTTAATCGACGCTACCCTTATAATTATTTTTATAATTTGCTCATTCTTTAATTATTGTGCATATTAATTAATTGTATTTGCTTATTTAATAGTATTCTTGTATCAGTTCTCATAAGCTAAGCGCAATGCAGAACAATACGTTTTGCGATAGCCCATACGACGATTTGCTTAATTGCCTGCTAAAAGTTTTGTTCTATATCGATAAAATCAGATCATCCGTTTTCTAAGTTAATCAAATATATTTGATTAATATAAAAAAAAaaTAGGAAGCCATGTATAAATACTTAAATGATGTGTCTTAATAACGTATGTACATAACATGGATAAACGGATTTCCTGTGCTTATCTTGTAAGTTTAAGCGGAGTGCTTCTAATAAATAATGGAATGATGGCAGCAACTGTTATGCCACGCAATATTGTGCAAACTCCGTTAACAGAAACTCCGTTAGTAAGCACAATTCATGAAGAGAACCGTGGATACAGTATTCCCACACCTATGGCAATTTATAGTACAATATTCAGCTTTAACCAGTTGAGATCGTTTGATCATGATGATGATAACAAAAGTGCATAACAATACTTATGATGTTTGTAGGGTTATAATTAAAAGCTGGTATTCATAGTAGATTCTTATATTTAAGGCTGCCTTAAGATGTCATTAACCAATTAGAGAACTGTATTAGCAGTTTAAAACATTTCTTAAGACGGTCTTGAAATAAGAATCGACTATGAATACTGACTTAAGCACAGTTTATAAGTACTAAATATCTTTTACAGTCTACTCGATCAAACCGTTAAATTATAAATTTTAGTATCTTTGTTTATCTTACAATTAATCATTTTTATCAAATTGAAATAGTTTCTTGTATCATACATTAAGTACATAAGTAAGTTAAATTAATGTTATAAATTTTACAAGTTCTATCTATTTGTTGTGCATGATATAGTGTTAATGTATTACTTGTTATAAAATTAATATAGTGTAAAAAATTCATAAATTATTTATTTTTCAGATTTGTTTAGTTAATGAACTAAATAATCAAATTTTACCGAATTGTAATAAATCCATTGACGGGTGGTCGCTATATTAGAAATATCTCACCACGAATGGAATATAAAGGCTATTTCAGTGTAGTGTCCAAACTCTATTGTACTGGTGTTAAAGTGAATTATGATCGACATATATTTTGCGAAATAAAATCTGAATTTCTATTTTATATTCTAAGCAACGTAATATTATTTAAAATAAAATTTCTTCCGTGATTTTTATCATATAAATTTTTCTCAGTAAGAATAAAGTTCTTGCTAAACTCGTATTATTATATTTTCATACATAATTATTATAGATATAACTAGACTATTTAAGAAAAGTATTTTTtATTTAATTAATAGATTGTTACAATTAAAAATTAAAATGTTAACGTTTCTTTATTTGAGTGTGATATTCTTAAAaCTTATATTTTTATATCGGTAGTAGCAACAGGAAAAGACATTTGCGATTAACACAAAATTATAGCATTGTTAAAAAAAaTATTTAAAATATTTTTAAATAAATTTTAATTAATGTCAGTACATTTTAATTAATATCAACACTGAAAGAAAGAAAGTGTAAAACTGTAATATTAAAAAGAAAGAAATACTATACATTTATAAAATCATATCAAACTCTGATCTTTGTAATATTTTTAATTCTTATAAAGTCTAGAATTTTCTTACCCAAATATTTTCTAAACACAATTTGAAGAAAAAATCTGCGATTGGTCTTATTAACTCCCAGTTTGGATAAATGAAATGAAATAATATGTAATATACAAATATTTTCTTAAAATACATGTGTTTCAAGAAAAAATACAGAATATATTTCATAACTACAAATGCACATTTTAATTAACGTACTTAATAAAAAGAAGACGCTAATATTTAGAACAAAAGAGATTGGTTAGATTTTTTTATTCTTCATGTTGCATCAGTATTTTGTCAATGCATATTATTTACAATATTGTAATTATTTTATATAAAAACAGACAAAAAGAATTATAGTTTCGACACATGTATCGAACGTTGGTATTCGCATGTTCCGATTTCGTGGCATACCATACAACTTGCCACTTATGGAATAAGGGAAAACTAGAGAGGAAAATAAAAGAATGAGAGTAGAATCGATAGTTTTTCCTTTGCCGAAATGAAAGCTACAATTGCATACATCATATTGCACATCGTGGTCTTTCTTTTATTATCAAGAATATCAAAGCAGTAAGAGTTTGATAATTTTTTTtATGTGAACTACTTATCTAGTGAGATAAGACAAACTTTCTATTTTAAATGATATGACTCTAAAGATTGTTTTACTCTAAAAATTGTTTTTAAAAGTCAGGCAAAAGAAATAATTGCAATTTTATAAATAATTTATAGCTTTTCATAATTTTAATTTTTTTTtAATAATTTTTCTTCTTTTCTTTCGTAAATGCCAAATGTATGTATGTATGTACGTATGTATGTATGTATGTAAATGTCTGTACACACACATACACAAATTAAATTTATAAATATATTTTTAAAAGACACCCAAAAATCTTACTCTTACTTTTACGATCTCTACTTTATATCTTACTGCTAAATTTTGCGTTAAAATTGTGTAAAAACTATGGAAATGTAAAGGTTTTAGAAGTAATATTCACAATTCTCAATCTTGAAGCAATTCATTCTTTATAATATTGCTTTATTTGCGTTTTCTACTTCACGCTCATCAATCTTTTCGGACAAGTCATAAAAATGGTCTTCTACATCTTATCCGACCTAGCCAAAAATCAATTTAATTGCTTTGGTGAAATCGAGTGCCATAAGTATAACGACGTGCATAACATTCGAGAATGAAAGAGAGGAAAATTGAAGAGTCATTAAAATCCCCTCTTCATGCGACCAATGTCACTTTCACCACCTCGCGTTCCGCTACTGATGAATATAAGACCACAAAAATCCAAACAAGCGGAAATTCTACGATTAGTACACATATAATAACTCTTTAAGATCAGGAAAATCATTATTAAATTAGTTTACAAATAACATTGGGGTTACTGCTTTCCGCGCAATATTGAATTTTCGCAGAAAGTCACGAGTTCCTGGGAGATCCATGTGACCTCTGTTAATTTGAAAATTAATTCCCGAAATAAAAATGAGCTTGGGATTCGCCGAGGATTAATTTACGCCATCAGCTAATACGGAACTAATGCGTCCCACGTCAAGTCGCATACCCATCGCTAATCTCTCTCTCTCCGAGCCATTCACCCTCCACGACTGTCTCCCTGCCTCGTTCTCTCTTTCTCTCTCTTCGTCACTCTTCTCGCAACGGATCCTCTTGCTTCCTCCAATCACTAAGTAAGCGACACAAGTGAGGAGTGTTAGGTGTGCATCGCGGATGCTGGAGGGATTTCGTAGGTGGCCGCCGCGGCTTCTCTTGCCGCGAACCGCTGGTGTGGGGATAACTGGAGCTTCGGCTTAAGTCAACTGTATCGCGTGAAGATGAAGTAGTACACATTGCCTCGTTGCGGAGTGCATGCGTCGGAGTGCACGCGATAAACATCGCGCGGATAGAAGAGTGATCAAAGAGAACCGGAAATCGTCGGGAGAATAACGTAAAGGACTTGTGCAGTTTGTTCCCGAAATTCTTGCTTATTAATGCATTAAAGCAGAAGATATGAGACTCTACGCTGTGAGTTGAATATTATATTCTTTATGTTTTTTCATTTGCACTTTTTTATAAAATATTTTAATTTGCTAAGTTTAAGTGTGACAAAAGTAAGAAATTTTCATGTTCATTTCATATCTTAACATTACGTATCTTTAAAATAGTTTTTAAATTCTGTATATAAAAAAAGTTAATGAGAATAAAAAAAAaCATCGGTTAAACATGAAATAAAAATCTTAGCTTTATCTATATATTAAATTTTTTtACTAAAAaTTTTATCTACAAATGTAAATTTAAAGCATAATTTTACCATAATTTAATTATATATAATTATTACATTAATTTAATTATATTAATTATAAGTTAAGTAAGAATGAATAATGACAGAAAAATATAAAGCTACCTTGATTATATATTTTCTACTTATTTTCTACTTTTGTTTATCTTAAACTTATTTTAAAACTAATTTATGTTAAATATTTTTAAAATCAATAAATAATTCAACAATTTATGCATCTTATTTTTGTCAAGACAAaTTAAAAAAAAAaTTTTtAaTTATAAAATTTATAAaCATTATTAATTAATATTTTTTGTATATTATTAATTTATATTAATATATATTATTATAATACTTATAAATATTATTAATTTTATAAAACCGATTTTAGAGTAAAACTTATTTAATTTAGTATTTCTTATCTCAAAGTCTTATTATATTTTTtATTTTATTTATTACAGATAAAAAAaCCAAATAATAAATACATATAAAAATTATAAAAATTTTTtAATTATCTTCAGAAAATTAAATTGTTTTACATTGTATTTTGATAAAAAATGCGTTTTTATAAATCTACAGTTGTTCGTACTTTTACATCGAGATGTAGATAACAGTGTCATTTTTTtGATGCACAGGATGTATCATAATTATATTCTCTTTACAGGTTGCTCTTGTAACATGGGCGGCATTCATAACAATATCTGCGGAACATAACATCGCAAAATTGAGTGATGAAAAGGTAAACTTGATAAACAGTATCGTATTAAATTATAATGTAGAAAATCACGTAAATTATTAGCAGTGAATTCTGGGAAAATGATTAAAATGCAGTGCTTTATTAATTATTTATATAATAAATTATATAATTGTATAATACAATTAAAATTTACCGTTAAAACTTTTTATTGTTAGTTGCAAATCTTTAAATAATTTTAAATAAAAAGAAATGAATAATTTATACAAATCTTGAAAAAAATTCGAGAAAAATATTCTATTCTAATTTGTCTTCAATAAAAACTTAGAACGGTTTAGTATAAAACCGAGAAAGTGATTTTGAGAGAGAGAATATGATCAAAAATCATATCAATGATCGAAAACATTGGTAATTAAATTTAAATCAGTGGTTCCAACACGTAGTAGAGAAAGTTCGAAGATGATTAAAACGTGCGTCGCTAAAAAAAGTTTTCTCTTTCAATTTCGACAGCTGTAGCCGTAGAGGGTATAATGACGGGTCCTAGAGTTTAGGCGAAAATAGAGTGCTTACAAACATCCTTAACCTTGGGGCATAGAAATCTTTAACCTCGATCTACTTGCAGCGCGTCATTCAAGTGCTACTTTACGTATAGGCGCGACGAGCCGAGATGAATTACAGCTGGGAGCTAACGTAGACTGAGTGAATGTCGAGAAACAGAGAGAGAAAGAGAACATTTTCACTTGTGCGGCACGTTTGTGCTAACAAAATAGTTCATTGGCTATGGTTCCCACCTTTTCTAAAATGTCTTTCGCGAAGTGCCAGAGTTCGCGCTTTTCCATTGAAAAACGCGAACAACTAATTTTTTTCCATCATTCGTATCTGCAATGTGCACAGTAATAAAAGACATTTATTGATAAAATAAAACATTAAGAATTTACAAATAATACATGAAATAAAAGTTAATTTTAATTTATATTAAATTTTTTTtGTACAAATTAAAACTAAATATTTTATATATAAATAACACATAATTAATTAAATACAAAAGTATTTAACTAATTTATTTAATTAATTTACTTAATTTTAATTAATTTATGAAATCAAATAGGTTTATTCTATTAATCAATATTTTGAGATTTAATCAATACAGAAAAAATGGCAGTCAAGAAAGTCGAATACTTTCGCGTACATCTTTATTTGCATATTCTGGAAATTTTCACGTTTTCGTGTCAGAATGTATCCTCTTTGCCTGCCAAGAAATTTCTAGTAGAATAATAAACTACTTATCCAAGAAGCTTTTTACAGCTGTACTTTTATTTTGTCAAAAAAGAAATCAAAAATGAAATTTTAATTATTCTATATTAAACATTAAAaGTTCTATATTTACCATATTATtCAATATATCACGTGTAAAATAAATTTAAAAAAATGACAATTAcATTATTTTAAAAtaCAAAAGTTAATAAAAAATTTAatGAAAAaTAAAaTAaTATNNNNNNNNNNNNNNNNNNNNTTAATATaaTAaTAgTAAAAAaTAAAAaCTTtaGTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTTTCTCTCTCTtCTGTTATTATtAATTTTCTtGAAAaTTAAAAaaGTAAAaCTGTgTGCATACTCATATTTATACATGTAAATAAAAGATATAAATTTGTTTCTTTAAACACGTTTTtAAAATTAAAATTAATTTTTTAACTTAACAACGTTAATTTACTAATTGAAAGTGAACGTTCTTTTGCTGTAAGGTAGAGTAAGTTATAAGATTTCTTTATACTCTCACGTGAAATAAAAACACATTTTCAAATCGTTTAAGGATAAACGGTGAAAATTTCGCGTCGTGCAGACtGGAGTCGCGTCAGCGGGTGGGTTAATCGCGGTTGTTTAGTTCAAGTGCATCTCGGGTGAAATTGATGCAATTGCTATtATACAAATACCGAGGCTGAATTAAGAGGCGCGCTCGCGGAACGTCGTCAGGGACAAGGTAAAACGCGACAACGGGCGAAGAATGCGCCGACGGGCACGAGGGGCATGTGCATTTTCTTTGCGTTAAAAGGAAACTTGCCAGTGAAAGTGGCCACACGCGGACGTAAATTCGTTCGCCGGTGATTGCCGTTGTTCCAACGAGATGCACCATCGCGCACCATCCATCGTGTGTTACACAATGTCACGCAACGTAGAGAAACGAATCGATCGACGTTTGTCAAGTGTACGATTTATAGTCGCGGTTGAAATTTTCCGGTCGAAGAGCTGAGAAAATTATATCTTGATCGACTATTTCTCAAGTTATCGAAAAAAAAAAaTAATAATAATATAATAAATGTTGCATCGTGAGAATCTACTTAATTCAAGTTGTTCGGTGATATATGCGGTTCTTGGATAACAAGAAGAAAATAAACAAATAAAAATGAGAAAGAAAATTGAAATGGATATGCGTTTTTGTCGAGGTGAAATATTCTCTGAATATCGTTACGATTTAAGCAATAGAAATATGCAGGTAATTCAGTGAATATTtATTTTCTTATGACAGGGGAACAATATATGGAGAAAGTTGTTTTCGATGTGTTTATGTATAAATCATGTACCAAATTGGAAAGATAAGGTCGCTCGTTCTTGATGTTCTCAACAAAGTTACGATTATTTCTTATTGACGCATTTGCCCCACAAAAGGCAAGGCGCTACTCGTTATTATTATCTTAATGTGCCATTTCTCTCTATTCGTGTCGGATAAACCAAAGATAAGGCAATTACGTCTTGATTTATtCGTAATATTTACGCATCCATGCAGCGTCATACATCCGTAACACACGCAAAAAGATtCTGATATTTCTAGTTCACTGAGAATACTGTTTAAACTAGGTCATTAGCAAAACGGAAAAATACAAAAGAAATTTGAATATTACGGAAAACAGTGGCAAATTTCTCGAAAAGCGTGGTATAATTTTCTCTGAACGCATAATATTATTCTTTGATAAAAAAGTGTATATATCATAAAAGCAAATTGCCGAAAATGCGTCAAAATTTACGTTCAATTTATTCAATAAAAATTACAGAATTTCATCAAGTTAAGCTTTAAGAATTTAATTGAAAATTTCGATTTATATATAGTTCACCGAGAAAAAAAGTTATTAAATAGATTAAATTTTTCAACTTGATTAAATTCGATTAAATTCTTCAGTTTAACTATTTATGTATTTGACTCAAAATACATAAAATACTTCGACCTTAATTTAAGCATTTATATGTTTAATTTAAATACTTAAAGAAATTTAAACAAGTTGAAAAGTTTAGTCAATTCAACGATTTTTCTTCTAATTGTAAGTGTAATAATAAAACTCTTATTCGAATTAAAGCTCATTATACTCGAAGTTTGAAACACTGAGAAATAAACATTGGGAAAATTATTGGAAGTTTCCATAAAAAAAaGGACGAGTAAATTTATAATTTATTCATTAGATTTCGATTAAGAGATACAACTTGAAACCTCAATCTAATCAAACCGATTCCTTTGTCATGCCGAACCATTCAATTAGAAGTACAGAAATATGTTTTGCGAAAGAAAGCAAAATATGTGGTTTCGGCAAATAAGGAGAAAGTAAAGGGTCCATTGGACGTGGATTGAGGACGTATCAGCTCCGCTTCGTTCTCGCTGGACCATCGGGATTTGCTCGACTCTCACTGGTTTTTCTTTTGCGCGCGCGGTGCAGGAATGCGGCGCATCTTTCTCGTTTCTCCTTTCTTCTCGCTCGAACGCCACGGGAGAAAGGGAGATCGGTGCCGGTACCGTAACTGCACCTTTCTCTCGCGCCGGACGACCATCAGATGCGTTATTTTCAGCCACCGCGCGCGCCGATCTCCCCGCGATGCGGAAAGATCGTCGTGCGGGATTACGACGAGAAATTACGGGGTGCCGCGGATTCTTTTTAATGGGTGTGTCCGTCCCATATAGCCAGAACACCGCTCGATTCTTTTCGAGAACTGGTTAATTATCTCTAGCAAAGATAATATCTGCTTAGCGAAACTTACTGACAGTGTTCTCTTTATTTCGTTTTATTTTATTTTTTTTCAACAACAAATTTATCGTGTTCATTTTCATGTCCATTAGTTCTTTACGGGCCAATTAGTCGTCGCAATTTCGAGAAAGTTGGTCGCCCGGATGATAGGAAATGACCAAAACAATTTCTTGTCCTACAAACTTTTTGGAGAATATTGTTCTTGCGCTCGATTACACTTTTTGCACAATATACGCATGTAATGTATATAACATATCAGTCGCAAGATGCCGGTTTCGTGTTTCATAAAAAAGTATGCCGATATCGCTACGTTGGAATGATCTAACCACGTTGGCTGTCGATTTTTATCGTGAGTACGCTATATTTCGCATTTTTTACGCCTTCTTCTTGCAAAATCTTCTGGGTCACCGCGATTTGCTTCGTTTGGACATCCATGGCGCTTGGATGCGATCGAGTATCTCGTTTCCTCCTCCGGTCAACATCCGAGAATACCGCAGAAAGAGCGAAAGAAAGAAATAAACGAGTGCCCTCAACGTGATAGAATGAGGAAAGTTACTTAACGAGCGTTCGAAATAATTTAAAAGCGACGTTGAACACGATAATTACGGCTGCTTAAGAAAATGAAGGGAAGTGTACCTCTTAATATCGTACAATAAGTTATATAAAATAAATTGTTCCGTGCGCGCGATTTGTGTAAATATTCTTGCAAAGCTGCAGGGTACAAATGAATGGAAAACGATAATGATGGTCACTAATATCAATTTTATATTGTTTTCCTATCAATTAGTCGTTTACATAATAATATAAAGCTAAAAACTGAAGGGGATATGTTAGAAAGATATTAGAAAATGCAATAAACAATATTTTATTACTAATATTTtATTTCCTAGCTCTCAATAATTTTCTGCTTAATTTTAATTCTAGTTTAGTTGCGCGTAATTTTTTTTACACGACGTGCTATAAATTTTTACAAATATATGCAAATATAAGTATGATATATTCGTAAAAAATGTATAAATTTtAAATTTTTTTtACAAaTTAATATAATTAATATATAATTTATTTAATTTtATTTTTGTGTACAATTATATAATTGATCAATAATGCAAATCAATAATAATGCATTAATTTACGATAATTAAAATAGATTTTtATTTAACAATTAAATTAAATTGATTTGCACATTTATATAATTATTATTTTATTTCCTAATTCTCAATAATTTTTTGCTTAATTTTAATTCTAGTTTAGTTACGCATAATTTTTTACACGGTGTACTATAATTTTTACAAATATATACAAATATAAGTATATCTTCGTAAAAAATGTATATCTTCGTAAAAACTTTGAAATTTCTTTTTTTAAATTAATAAACTTAATATAAATTAATCTAATTAATATTTATTTAATTCTATTTTTATGTATAATTATATAATTGATTAATAATTAATTTACGATTATTGAAATACCTAAATTTTtATTTGATTAACAATTAAATCAAATTGATTTGCACATTATATAATATGTACTTATAAGCTGGTAAAATTTTTACTTTTATAATTTCATACAGGAAACGCAGCTCCGCAATTTCCTGATGTAATTTTCCTTATAAAATTGTACCGAGTCGTCGAGAATTTTCTAGGCAATCACTGCAACTGATTTATTTTTCAGGTTATCGATTACACGACGTTTCATGATTTGCCGTATGATTTGAAGCAGATAGTACAGCCGTACGTGACGGACGTAGAGGCGAAGAGTTCTGGGCGGACGGACGCCGAAGATCATTCTGACGTTTTCCAGAATGCCGGATTAAGTAGATCAGCAGTTCACGCCGGCGAAGAGAGAGGATCGAATGGTGTTTCCACGACCGATTCCTCCTCGCCAGGATCGATTTATGCGACGCCGCTCGCCGAGACAAGTATCCGTTTAGAGACAACCGACAAGTATCCATTTAGAGAGTATGCAAGTCACGAGCAGCCAAGGTACACCGACGATGTGCTCCTCGTCGAAAATGCCGGTAGTTTTGGGCAAAAAGTCCAGCACGGTCACCCGCGTGACGAAACGATTGTCAGGACTACCGTGCGGACCAGCGAGGGCCAAAGGGATGGCGAGTACACGAGTTTCCAGAGGCCCTTCAGCAGCACCAGGTCGCCTCTCGAAAATGAAGATGACCGTAAAAGGCCTCACACGCCGGCTACTCGGGAGGCATTTGTGCTGAAGAAGGAAAGTAATTTTCCAGACGACGATTCGTCTTCTGACGATTCTAAAGTAATCAAGTCTGAAACATTCGCGGAAAATTCCGATAAAGTTTTCAGTGAAATCACAACGGAAAGCACGTCGCCCGGCAACGTTGCCTCGATCCTTGAGAACGACATCGTGCCCGAAATTCTTCCGACGCCACAAGCGAGATTATTTCGAGCGCGTAATGACACCGCGGATGAAAAAACCGCAGAGAAATCTATCGAGTCTGCTGAAAAAACGGAGAACGTTGTGAGAACGTCGACGTCCGTGGAGATCAGTCCCTCGCTTCAAGTGAGATTTTCAGGCCCCATCGTAGTGGCCGACTTGCCTAATAGAGAAACTCAGGAGATGGTTATTGATTATATGGACGATGCATCCGAGGCGTACAGGCCAGTCGAGAACGCCGAGATTACCGCGGAGGCCAACGCCGAAGGCACCAAAGTGGCGGCTTCCTCCAGCATAACATCCTCGGTTATGCTGAACCCGCTGCAGGTCGGAATCACGCTGATGAACGCCAATCAAGGTAGACTGACGGACGAGAGTGAGCAATCTGAGACGATAGACTATGTCCAGGACTATCCCCAGGAAGATCTACAACGCTTAGGGACTGCGGATAAGGAATTTGTCAAAAGCAATGGGAACCAGTCACGTATCGATTACCAGGATGAGAACTTTGAACGCGAGATCGAGAAGAGTGTTGGAATCGACGCGCAAAAAGTTCCCAACAACTCGGTCGAGATTCAAAAGTCCGTCGAGCTGTACCACACCGCGCCGATACAGGAGATCCATTATCCTCCGGAATACGTTCAAACTACAAACCTCGGTGTCATCGAAACGAATAATATTGGGAATTTACAGCGATCGAAGCAACCATACGATCAGGTCGAGCAATCAGAATTGCGGCCGACTTATAATGTTTATCAAGGTAATACGATATTGCCCATCGATCCCTCGATCGTTATTTATTTCTTTTATTTTTATTCAAGAATGTGTATTACATCTATTTTTACAAATACATTAATATTTATAATTTACATAAATTGTATACAAGTAAAAATTGTGTGCTTGTAGTATTTTAATTTTATTAAATTATAATATATTTTTACAATTTATTTATTTTATTTCTTATCATTTTTTACTGTTGTAATACAAACATTTATAATGTAATGACGAAATTCTCAATTTTCTTGTATAAGTACTTTAAGAAGATTATTTAAGATGATTTATACAAAAGTTCTTGGCTTACTTGTTCTGCAAATAAATAAATAAATTTTTATTTACAGAATAATTTGCAAAAGTAATCTTTGTATCGCAATGAATCTTTACATAAATTGTCTTAAATACTTAATTAATAAAAAaTAAGTTTTTTtATCATAATTTCTTAATGCATTTTTAATAGAGCACTTTTTATTAAAATAATTTTTAATAAGAATTAATTCAGTTATAAAATTCTAATACATCCTTAATTCTAATCTATAAATGAAGTTGGTAGTTTGTGTAAATAACGAGAACCCATCAACGAATAGAAAATTCTTAAATCATTGTTACTCAAATTATAATCACAGAGAACCGTTTAAAATATTATATCAAAAATGTAATAGAAATTAATGTCGCAATGAAAGAGAAAATGAGAGCCGTATCTGTATTTTATTTTTtACTTTTACTAGATATAATAGTAATTCTTTTAAAAAATTTAACAAACATTTATAATAATTAACCAGTTATGCAATTATTTAATTTAATAaTTATAGTAACAAACTAATTATGCAATTATTATATTTATATAAATTAAATAATTAAACAATTATTAAATTGATAAATTTACAACTAATCGGAAACGCGGAAAACTGGCTTCAAATTAGATAACATGCCAATTTTAAGATAGTAAGATACGAAGGCCGTCCAAAATCCGCCCAAAATCTTATACGAACGTTGAAGTTAAAGAATTGCCCTAATAATAATTTCGAGACAATTTAACTTTCACCGAATTCCTTTTAACGCGGAAAAAAGTCTGTATGACGCAAGACACAAATTAACATGCAACGACGGATTAATGCTCGCCATCTGCGCGTAATAATACTCGCATTATCAAATCACGCATCAGCGCCACTACAAATTGCCAGGTTTCACCCATATATGCGGTGGAATGCGGCAGACACAATGCATTAATCTCGCCTTCCGTTTCAGGTAACGACCAGGACGAAAAGAGCGTCATTAAGACGCACGCATCCACGTTCTCGCAGAACCTTAACCGGCACGAATACAACGCCCTCGAGGAGGACGCTGGCAGACCGATGACCTCGGCCGTGGGCGCCGAGTACACGTCGAGTACTACTCGCGAGCAAACACCCCTCGAGGTGCAGCAGCCGATCAAATACAACGGCTACCAGTCGACTCTGTTAACACCGAATCAATATGATGACACGTTGTACGATCAATCCAACGTACGACAGAATTTTAACGGCAACGATAACGGCGTACCGCCACGCGCGAAACTCATCGGTAGCTCCACGAGGCAAGAAGCAGCGAGCGAGCCCGTGAAACCGTACGTACCGAATACGTATCAGTATTCGGTGCAGCAGCCGCAATCGAATCAACCGTACGATCATCAGCAGCAATTTCGATCGCCGGAGATAAGGCGACCGGAGGTTCAGCAACTCCTTCTCAGGATAATACCCGAGGGAGCGTCCGCGAACGGAGGCTTCCTGGTGCCGATCCCACGACCCTCCTACCCTATCGAAAAGATCGTTCACATGTCGCATCCGGTCGAGAAGATACCGGTGGAGCGGCTGGTTGAGAAGAAGGTGCAGATACAGATGCTGCCGCAGCAGTATCCCGTGCACGTGCAGGTGCCGGCCGAACGTGTGGTGGAGAAGCAGATCCGCCTGCCACAGACCTATCCGCTCCACATTGAACGGGTGGTCGAGAAGAGGGTGCCATATACGGTTCAGCGATTAATAGTGCAGCCTCCTCCGTACCCGCTGCACGCCGTGAGACTACCCGGTGCGGCTTACCCGGCGACCTATTCGGCAACGGCACCGATCGAGCAACCGGTGCACGCAACGGTTCCGATGGAGAAGGCCACGGAGAAGCCGGCGGTCTCCTCGCGGCCTCCTTCTCCTCCTCGGCCGCTGTACCGCGTGAACACGGACAGGCCGACTGGCGGCGGCAACTCGGTCGAGACCAGGTTCACCAAGTATTACCAGAAGCCGCAAGAAGCGATCTTTGCCGAGAACGCGAATCTCCAGCACGGTCTCGCACCCGCCGGCGGCTTCTCGTTCGCGCCGCAGCTGCAGAGCGACACGAACGTGTCGCAATTTTACAGCATTCCCTACGGCAGACCGTACGACTACAACATCGACGTCGGCAAGAACTTTGTTCCCACCGCGCACTTCTCCAACGTCAAGCTGGTGATCCTGCCGAAGAAGTTCGCCAATCACGTGATATTCCGGCCACAAACGACCACGCCGGCGTACGCGATACCGTCCTTCGGACGGCAGATCCTGTACAATCTGGTGGAGAAGGATAAAACGATCAAGGACGAGTACGTGGGTCCTGCGCCGCCGCGCAAAACCTCGCAGAGCAAGGTGTTTCTTCAAACGCCTGCGAAGTCGCCGCAGTTCACCACGAGCGCCGCTCAATCGTCATTAGCCGCGCTGAGAAAATCCAGGCAACCTGAAACGCAGCATCACGGAAGTTTCAGGCAATCGAAAATGGAGTACGGCTTCAAGCCGCCTATGGTGCCGTCCATTCAGTACGACGAAAATACCGCCAGTAAAGTAGAGAATTAACGTAACGGCTTATGATAGTAATAGTAATATTAGACAAGTGTCTAAAATGCGTCATACAACGCGTCTAAAAAAACTTTCCATCATTCAAACGTATCTTGAGCATATAATATTTTAGACGTTTCTTGCATTCTTGCATTATTCAAATGTTTCAGAACGATTCGTGGATATGATTGAGTTAATGAAAGAGATGTTAATGAATGAATAGAAAAGAGCCAATTTACAGTACTTCCTTCGTATCCATGAAGATTTATTTGTGACACAAATTTTAGATTTTAATATTCTTTTTATATTACATGTATACTTATTATTGAAAATTATATTTTTCAATCACTTGAGGTGTTTTATAATTTATTTTGATTCTAATAGTAATTTTACTGTTTTGCAATTAATATTAGCAATATATCTATTATTATATTCTATGGTAAAAtGTTACATTTTGTATATTTTATGTACCTTGTTACATACATAAATATCTAAAATTATTTTATTACTGTTACAAATAATTAGGAGAAAAGCGACAGTTTGCAAACATCATAACATATAAGAAAGTATTGTAATGTAATATTCTGTGTTAACCGTAAATAGAAAAAACGATTTAATATCGTTACTGCTAGCACAGTACGATAGTTACGATAATGGAATAAACACATATGTAAGTTTTGTACAATATATTTTCTACTTTCATACAATACTTCTCGCTGTACTGTTTATTTCACACATTTTGATTCTATTTTTAACAATGATACTTTATATTGTATTAATTCAATTTTTTTtATTAATTTtATTTTtATAAATTTCTACTGTAGTTCTCTCTCCTTCTCTCTTGTGTGTGTATTATATGTAAATATGTGTACTGTTATGTCATCCTTTATATTCCAACTCTAGGAGTTGGACGTAAATAATTTCTCGTATTCAGAAAATACGCAAACATTTATTAATAATTATATAATCTTATCTTATATACACGTATACAAGGTATATACTTATGTATATATTTATACTTAATACTAAGATTATAATGGTTTACGTTTGCATTCATGATATAATTACATATAATACTTATATATACATATTTTTCATGTTTtCTTCATGCAATTTAAAaCGTAAAATCGCTACGCAATATAAAGCAGACCACCTCTCAATAAGAATAAACAATAACTACAAAATCTTCAATtACAATGTTGACAGATGTTTCATGAACTTTTTCATATTTTCTTTAATATCTTAAGATAGAAGAAATAGATTATGTTATAAAAACCTTTATTATTACAAAATACGAAATAGTATCATGAAAACTACTATAATATACTATCTGATAGAAGACACTTTCTACTTTATATTTATGTTTTCAAAGTTTTATTTTTAATTTTTGTTTAAAAATATTAAAAAaTATTAAAAAaTAAAaTAAAGTACCATTATTAgCGATTTTTtATAAGCaTAAGATTTTTtACACACGCGCGCTTTcTCTCTCTCTCTCTCTNNNNNNNNNNNNNNNNNNNNCACgCGCGCTtCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCGCTCACCCTcTCCCCCCcTcTTCCTCCTATCCACTATATAGACTTCTATTTTCGTTtACAATATTACAATATTTCAATATTTAATTATTTACATATAAATTATAATTTATTTTACATATTATTTACAGATAAATTATAATTAATAAAAATAACTGATAATAACTAATAATAATATTTTTATATTTCTTACACACATACGTAGATATACACACATACAGCGAATTTTTAAATTGGACAATTCGACAAGTTGTATAGAAAAACATACACGTTTATCTCCTCTTTTTTTACTATTCCTTACTTTGTCAATATTTCAGAAAAATTTTAAAAACTTTTTAAGAACGACCCCAACGTTCACATGTCTTATACGATAAATTAGGCAAATTTTTCAGAGCTCAAAAAGATCAACTTTTGGTCGACTGTCAATCAAATGTCGTTTATATAATAAACTGCAAAGATTGCGAGGCCTCATATGTGGGGCAGACGAGCAGATTTTTAAATACTAGAATCATGGAACATAGGAAACATATCAACAGAAACGCGCGGTTAAACATTCTGTTATCACAGATCATAGAATTAGTTCATCACATGAATTTGATTGGAATGGGGTTGAAATTTTAGCCAGAAAAAAGTTTTAAACAAAAGACTAATATCAGAAATGATTTATAAAATCATTTATAAAAATAAAAACAGCCTCTAAATTCGCAAACAGATACAATTTTTTTACATCCGTTAGAAACCGAATTATTTACTAATGCTTGACGTTTCTGTCTCTTATTTCTCTTCGGATTTACTGTTTATTTATTATATATTCACTGTCAGCTTTATTACACCGTTTAGTTTTTTGTAACCATTCGTTCTATCCACATCGCTGTTACTTTGTACATCCGCCTCGCGTAAATTAATCTATCTCTGCAAAATACTTTTCTGTGTATGTATTGCTTAGTATTGCTTCCTTTTTTTTATTTTATCTAATTTCGATCATTCAATGTTTTTATATAGCGCTATTCTTAAACAAATATTGTACATAATTGTTTTAGTACGACCATTCGAAAAACTTTTTATACAACGACACGGACCATAACGTATCACATTGACTACAATTGTACTGCATCATTTTAAACTGACAATTTTTGTACCTGCGCTACACAAGCCTGATTATTAACCATCGCATGTGGACTGAAGTAATAATTTTACACCGAGGATCGAAACGTCTGTAATACTTTTCTGTTAATTACATTAATTCTCACATGAACATCTTGTGTTGGCTCACGGTATTAATTCATATTTTAATTTACTTTTTCAGAGCCTTTCTCATTTTAAATTTAATACATGTTTAGATTAGTATTTAATTGTTTAAGTAAGATATTCTTAAGAAAGGACAGAAATAGACAGAAATTTTTCATCATAACTTAAACGTAAGTCCGATTAAAATAATAATTGTATAATAAAATGAGATAAAACAAAAAGTTTAAATCTGTTTCTATTCATCGGTTTTTTAAACAGAGTTTTCTGGATTCATATATCGCTTTTTACGACGAGATCTCGCACTCTCGTATACTAAATGCAGAAAGAGGAGAATGTATCTCCGAGTAATACATTTATACGTTGTGCTTTCAGACTGTTTTGAAGTTTTCTCGGGAGGCCATTCCCGGAAATTATGCCGTAATTTAAATGCATATTGTAACTACAGTTTCTACACGCAAGTTATTTTCACATTAACATAAGATAATGTATTTACACAAAATATTTACAGTTATTTACACAAATAAGTGTAAATAAGTGTATACAAATTTTATTGGTTTGTGAATATTGCAGAATTTCGAGTGAGCGACACCGAATTTGAATCCGTGAACAACATAGTTCCACGGTCAAAGAAAGCGATTTTGATTTACAATTAGTTTCCCAAACGCCGTGTGAAATCGCGGAAAAAGGGATTCTTTGACTTACGATAAACCAACAAAATAAAGCAAATGTACCATCATGCAGTATTTTTATAAATCGTGTTTTCAGACTATTTCCGAAGCTATATAAATTTTCATTAGATTGCATAATACTAAATTGTTGCAGCATTATAGCTGTTCCACATAAATTAGACAACTGTAATAATTCCTCTTTTTTCTATAATTTTTAACCTTTGGAGGTCACACAAGGTTTAAACGACACACTTCGATTTTGAAGGAAAGTGTCTTCATAGTAATACCTCATCAGCTGATATGGAACCAGTCGAACTAAACAGAAACGTTCTCTACCATTTTGCATCCTTTGCAATAATTAAACAGATGTTAATTATTGAAAATCGCCATATGCTGGAATTATCTAATTAGAACTTAAAATAGAGCGTATGACATTATTACATTAACCCGCTTTAATTCGATAGTTCTTCAATAGTGTATTAGTAATTTGTTTGTATTTTTATAGTTTTTTTTtCGTAAAAGTATCAGGCAGTATATCATCTAATCCTGCACAAGAAGTAGAAAGGCATTTCTTTAATAGTAAACAAGATTGCTGTCCATTACGCTTTTATATAAAAAATTGTAAAATCAAGTATCAATGTTCTTCCTGTGTACATCCGATGTGCGACAGTCATCATCTTTATTTATGTAACAATTGCGGCAAACCAAAATAAATTTGCAAAATTTCATATTTTTTAACTTTTAAAACCATTTCAGATTTAAAAAAAGTTACTTTTGCACTGATTTTGCTTGATAAATTCAATTTTTTTTGTATAAACGTAATTTTCTTTCTTTTTTTTTTTTTttGAAAAATTGCCAACATTATATAAGTAAAACAAATTCATTTTCTTAAACATTTACTAGAAAATTATTTTCAATAAGAGTAGCATATTTTAAAAGTATTACCATAACTTTTAGTAAAAATATTGAAGAACTTATAATTATTTTAGGTAAAACGTGGTTTTTTTCTTATAAACTTATATTATTAAAAAGTGTTTACATAATGTAAGTGTAATTTTAATTATTAATTTTTTATGAAGAAAATGCATTCTATAATGTTTAAAAAATTTATATAAAAATTTTTCCGATCTAATTATACTGTCTGCTTTTATACGTTAAGTTACACAGAGGTTAAATTGACCCACAGTGACCACCAAATTTTAAATATGGTGTCATATTCCCTTCTTTATCAAACCATAGATCATATAAGTCTTTGAATGCTTTAGAAGCATTAGAGCCTGATCCTTTTAAAACACTGGAGACATTAGTAAGAGTTATTTTATTTTTCTCTAGAGTTTTTAAATATCTGGTTTTATGTTCTTCTTCATCGAACCACAGATCATGTAAAGTCTTTGAATGCTTTAGGAGCTTTAGCGCCTGATCCATGCAAAATAGAAGACACATTAGCTACATTTATTCCCTCTTTTTCTAGAAATTTTAAATATTGCGTTTTATGTCCTTCGTTATTAAACCACAGATCATATAAGTCTTTAAATGCTTTAGGAGCTTTAGCGCCTGATCGACTTAAAATACTGGACACATTAACTAGATTTATTTTTTtCTTTTTCAGAACTGTTAGATATTTTAGTCCTTCCCCATTAATTAAAAAGTCCAAGAATTTGTTAAATTCAGATGTTTTCGCACTGCCAACAATACATCTAGCAAATTTAATTTCATTACAAGTATGTTTACTTTGAGCTGTTTGGTAACTGGATTTATTATTTTTTATTTCCTCAAAAATCGTTTTCATTATTCCTTGTGTAACAGGCCCGAATTCATGGGACTCTACCCAACGTAACGCTAATTTATGTAATTCTTCATAGCTGTATGCGTAATTGTGTGACTGATTGTGAGTTATATTTTTTCTAATAAGAGTATTTAATTTTGTCTTATTTGGCTGATTAACTGCAAATATCAATTTATCTAAAAACTTTTCTTTTCTTTCTCTTTCACTGTTATTAGAAAGTATTCCCACTTCTTTCTCTTTTTGCAAGGAAGGCGGCAGCTGTAACTGATTTATAATCTTCTCTCGTGTTACTTTTTCCGAAAATTGATAAAGATTATTTTTGTTTATACACGAACTATATCTTAAAACTCTATATTTTTCTTCACAAATATTTACACTATTAAATTTGAAAAGATAGGAATCATTAGGTAGCCTTTTTTTTAACCTCTTTTCTTTTGTGAGATCTAAGTTTGCATTAGTGTAGATAATCAAATGTTCTATATCCTCGCTAAATTTTTCAATAAATAGTGTAAAATATTTATTAATGGAGAACATATTTTCTTTCTGTCCAAAGGAAAACAACTGACTACTGTCTATATTAGCATCTGCGTTGTGAACATAAAGGTAAGAAATTTTATTTTGATGATAGATAGCAATGCTATTATCATTTTTTCCAAAGTTTATGGAAAATGCATTTTTATGCACAAATACATCATGAAAGAAATTCATTAGTACATTAAACTGATATATAACTTCAGATACATCAACTCCACATTTTATATACTGATCTGAAGTTTCTAAGTCACATAATATTTTTtCTTGTAATGCTACATAATCGTCTTGATCTTTACCATATTTTTTCATTTCAATTTTTACAATGCTGCTCAGTTTTTCTCTGTTAGGCTGATTAACTGCAAATACTAATTTGTCTAAAAATGCTTCTTTTATTTTTTTTTCAAAATCCTGAGTAAATTTTCCTTTTTGTACTACTTTCTTCGTAGAAGACAAAAATTCCAACTGTTTTAAAAGCTTTTCTCTTGTTGTTTTATCTAGCGAAAACCGATAAAAAGCACCCTCTTGTGTATCATCGTTTGTAAATAAAAAATCTTTTAAAATGTCACATTCTTCAATTTGTATGTCATCAAATTTAAAAGGATAAAACGTTTTAGCTCGTCCTATATTAAATGTGTTCTCTTTTGTAAGATCCAATTTTGAATTAGTATAAATAATGAGATATTCTACATCTGTTAATGAATTATCTGTTGTCAACATACGTTTAGCAAAAACATTAAAATAATTATTAAGTAAATGGTTGCGTTTTGAAAATAATTTGCCATAACTAGTACTATTTTCTGTATAGTATTCATCTACATATTCAATTCGTATATGAATTGACTTCTTTTCATAACGAATAACAACATTGTTAAATTTATCAATTTCAGAATCTTCAAACGTTAATGATAATGAAGGATATTTATGTTCATACGTAAACTTTCTAAGCGAGCAAAGTACTGACAAGTTTAATTGATACATAAGTTCGATCAAGTGATTAGAAGAATGATGTCTGTGGTGTTGAGTACGATGATATGTATACAATTTATCCTGTCCAGATTCATCTTGTACATCACTAACACATCCTAAACTCTCTTGTTTATTTGAATCTATGCGTATTAATTCTATGCGCAGTCTCTTTAATACTATATCATTTCTGTCTTTAGGAGAACGTTTCCTTTTTTTAGTGTTTACACTCATTTTACAATTTTTCTTTCTTAAACTCTTTCCTTAAATGTCTCTTTTACTTGTGTGAAGCACTTCTAATATCTTTCAATAGATTATACAAATTTCTATTTAATATAAATATCTCAAGAATTGTTTTCGTTATCACTATGTTATTTACTGCATGATAATAGAAACAGTTAATAAAGCAAGTTATTTTTTGTGACTAATTGTATAATTCCAACATGTTGCCTTATATTAATTAATTTTATATCTAGAAAAAATAGAAAAAAAAGGAACGTTTTTTTAGAAAAAGTAATGAATCAAAATATTCAGAAATGCAGTAGAGAGTTAATAAAGGAATTTCTATATTGTTATAAAAAATATTTAGATATTAGCAATTTTATATACTATTTAGAGCATTTAGAAATACTGATAATTTTTTAAGGCTTTAAAAAAGCTATCTGAAAAGCTTTTACGAAGTATGCGTAATTTTCCTTCAAATGTATTCACTTGAAGAACAATAGATTTCCTTTTCTTTTGTTGGTTTCTTCACATTACTAACATACCATAAACTTTTgctacccgtatgtcgcgtatttctaaatacaatatatgtgtttaaccatgNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN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AAGCTAAAAGTTTATCTTACTATTACTATTCATCGATATAAATTACCTTGTTTAATATAATCGGTGTAATATCAAGGAAATGTTAAAGTATGCAAATTTGTCTGTTGTTTAAATTTAAGCAGTATCTTGCAATAGAAATGAGCGTAATATTTGCAGCGCGATTAACACAGCGGAGTTTATTTCTTCCTTCTCACATTGCTCAATTTCATTATGTTTCGCATTCACCTGGTTAAACTGCACTTTTTATTTGCAATAAAATTTGGTAACACACTCTGTATCTCCGAGAGCATCGTTGCGTATCGCTCACCGAGCCATGGCGCGATTTTCCGTAATGTCTTGCAAATTACAGCTTGCCATGTTTGACTCGTTAAAAAGTCTGGTAAACAACATTTAACGTAGCGTAACGATTTAATAATATACACGTTAAACGTTAACAAGTCATACAAAAAGCTCTGCATTTGCACAAAGATATAGCCAGGCATTCCAGGCATATCGTGTAAACAGGCACATTAAAAGCAAATGGAACATCGAAATTAACATAAATCGATTTTCCGCGTGTATACGTCGAATGTGCAGAAACCGCATTTGATCTCTCATTCCGGTATCATTTTCCGTGAAAATATTCCTCTATAAAATGTAAATGTATCGTCATTACCAAGCTACTGAATAATTTGCGTTGTTAATGCTGTTCGTCACAACGAAATGCTTGGAATACTGTTTCTCTAAATGATACGTCAAGCAAACAAAAaTCGACGAAAAAAATTACACAGAAAATTTGGAAAATGTTATGTGTTGATTATTAATTAAATAATTTAGCGAAAAGAACGCTCTTCTCTCATCTTTTTCTCTTTTTTATTTTGACATATAACATTCAAAAGACATTTTTTGAAGCATTACTAAAGAATTATCATTTTAATTGTGTATATGAATATACATACATATAATGCGTAAACAATCAATGTATATAGTACTGGGCAAAATAAATCATACAACATTTCAACCAATTGAATTTCTCAGTGTAACTATTTTTTTTtAATAAACAGATTATTAGATACAGTAAAATCAAAGCATTTCAAAGTAAATAAAGTAAATAAAGAAAATATAAAATATTTAAAATAAAGATAATAATTAAAATAAATTGTGCTCAATTTTTATTATTTTATATATGTATATTTTCTTTATTCAATTAATTTATTTATTTTGAAATGCTTTAATTTTCCTGAATCTAATAATCTGTTTGTTTGTTAAAAAAAATAGTTACACTAACAAATTCATTGTTGTATATTATATGTTTTGTTCAATACTGTATGTAAAAATTTGTGCCAAAAATAAAATCGAATTTTTGGGTAGATTTTGATAATTTCGGGACAAAGTGATTGTGGTGACACTTCCCCGATTCTAATGACGGGCGAAGTTACTTATCCACGCTTTGTTTGCAAGTCATCTGCCGGCATGAACCGGCAATCATCATTCGAGTCGTTATGCGCACAGTGGTGGGATTCCAGCGATCCGGCCGGCGCGCGGTTGTAAGGACGCGCTGATGAGGGAGAGATTGCGTGACCGCCGGCGCTGCATTGCGAAATGGAATTATCCGCCGTTAGGTAATCATAGGTAAGAAGAGCAAATAGCGTCAAATTTAAATCAGATTGTATCACCGCGCGGCATTCCTAACCGGTGGCTCTCCGGCTCTACCGTAGAAAGCAAGCAACGCGTGAAACGCATCACTTAGGAAAGTCTCACTTGAGTTTAAGTGCCGGCGCGGGTACCCCCCGTCAGCTCCGTCAGCGACCGTCTTTGAAGATGATTGTCGTATTGCACGTACGGTATAGTCATGTATAGCAATAATAATTATCTATCATAATGAAAGTAATATATAATAATAATGTAATATAATATATTATCTCTGTTTAATACCAACGTAAAaTGTTTATAATTATAATTTGTAATATTATATATAAAATTATTGAAAAGAGCCCTTAAATCTGAGGTCAAATAAAGTTAATTATTAAACTCAATTTGCTAGTTTGTCAACTAAATTTTAATTATTTTTtATTTTTTtATCATTGGTGACTACAAGTAAAACTACACTGATTATAAAATTATATTTGTAAAATTATATTTGTAATATTATAAAGGTATTATAACTTATAATAAAAATAATACCCTTTAGTATTAATTTGTATATATTTTAAACATAATTTTACTATTTATTCAAGAATAAGCAATACTTTAATGATTATTTTAATCGATTAAATTACTTCTATAAATTGTTCTTTACTCATTTCAAAATTCTAAGGATGTACATAATCTCATATAATACACTTGTGTGCCGCTTCTATTAAGTAAGTGCGTTTATAAGACCGGCAATTCCGCACAGTGCACCGTCAACTTGTTGACAAATTGTGGGATAATTCGGGAACAGAACTGTTGTTTCGTCGAGACGAGCGGTATATGTCATTAAAAACGAATAAACTTCTGCGGGACTGTATCACATGTAAAGAATGACAATTCGTCCGGGTAGCCCCGTCGCAATGTTTTTGTTCATTAAATTGCAACGGTTTCTCTATTCTCTGTACAGTATAATGTGTATGTTACAGTAGAAAATAAACATAAAACCGAACAATCAGACAAAAAAGTAGTGAAGATGTTAATTTTTAAAATATTTTATAACGTCTATAATCTCGAAAAATTTGAGACTAATATTGCATCGAATTAATTTTACACTTAATATTTATTTAATAATTAATCTCATATTTTTCAATTTACAATCAATATTGCAATAAAGTTATTGTAACTTACTATGTTGTAGTACAGACATGTCGAAAATTTTATTCCTTTCAAAATTAAATGTATTGTTAAAATTTTTAATATTTCGAAAGAAATTTTTCATAGAAATTAAGATTGATTAATAGATTTAATTGTTTGACAAAAAAATCTTATTAATCGTTAATTTTCAAAACAAATTCTTACAAAAATTACAAGTTCCATCAATCTCTTTAATCCTAAACGGAGTAAATCTTCTTAGCACGTCATATGTAATGACATATAATAGCAAGATAAATTATCAAAATAGCCTTCCTTTACAACTTCAGCCTCGAATTTCTCAAGATTGCGATGATGTTAGAGAATTTCCAGTCATAATCCTATTGAGCACAGGAAAAATAACAAGGAATCTTTCCTTCTCGTTGAAGTCTGCTACCTAGTAGCCTATATGCATCTTTCTTATATACTATATTTCTGTTAAAGTTACACGAGAAGATAAAGTATGCCCATAATCGGATCCGCGCCGTAAGCGAAAGGATTAACCCGCCGTTTGGATCTTACGCGGTCTAACTTGACGTAACGAGCTACATGCGTTGCAGCCAGTGTTGCTAGATGGGTCGCTTTTTTCGCGCATGCGCAACAGTAGAGGCTTTTAATACAGTGCCGTATAGTAATACATATGTATAGGTGGGAAATCTTGGCGAACTGTTGCTGCAAaGGTTAAaTGTAAGCTATATTTCAAAACATTCTTTTCGaGAAAAATTTTACTCAAAATAGTATAGTATACGTTaCGTgtattatatattttaagttaaaatttttttctaaaggaacgttttagaatctaatcttaaaagtgtaaattattttgtacatcaattatttaatttttttataattatttttgggcacgtgcatgtaaatcttaNNNNNNNNNNNNNNNNNNNNatgcgcaacagtagaggctttttaatacagtgccgtatagtaatacatatgtaTAGGTGGGAAatCTtGGCGAaCTGTtGCTGcAAAGGTTAAATGTAAGCTATATTtCAAAACATTCTTTTCGAGAAAAaTTTTACTCAAAATAGTATAGTATACGTTACGTGTATTATATATTTtAAGTAAAATTTTTTtCTAAAGGAACGTTTTAGAATCTAATCTTAAAAGTGTAAATTATTTTGTACATCAATTATTTaattttttATAATTATTTTTGGGCACGTGCATGTAAATCTTATTAATGTCTAAATAACTAATATTTTTtCTTTTtAAGAAGCTTTTTTTTtATtATTATTGAAAGACAGGCTCTAGTAGTACCCTTTtCCGTATGGTTATAATACTTTACTGAGGCTGAGTTTTATGCGCATGTGCAAAAAAAGCGACCCATCTAGCAACACTGGTTGCAGCATTAGCATATCGTTACGGTTGTCGGTGCACGCCGGTGCGGGCATATTAATATTATGAGGATGATGACACCCCGTCGCTTGCGTTACATTGCGCAGAGATCTTTCAAGGACACGCGAGATCGGTGTGCGTATTCACAAAAGAAGAAGAAGAAAAAGAAATGAAAGGTGAGAGAGCGTCGTTAGTAATGCTCCAGATGAGCGTGTGCCCTTCCTTGTGCGCGCACGCGGTGACGACGCGCGGCGTATGTACAAAGAGGATCGAAAGGCAGGATTTACGCAGCGAACGGGCACGCTGCTGGAGGATTCCGCATAATTAAGGCCCCCGATTGCGCAATCCTCTAAACGGGAGCGATGTTACTCGCCTACTGTGCGTGCCTCTTCGACGTAATCCTGATTCAGAGGCGTTTACATCCTCGCGTGTATCGTGACTTGTAGAGTAAAGGCAGGTAATGTCGAGTAAGGGATACTAATATGGAATAGGGGATTCGTATTTTTTTTtAAAGAAAGCACCCGATATTCAGGTGATAATCGTTGAAAGTTAAACATGCTATGATGAACAATGAACTTGGCACGACAATGGCTTTCTTCGACATAAGTATTTACTTTATTTTTGTTGCACTCGGAGATATCACGGCATTGTATTTTATTCGCGTTCTCACAAACTGAAAGTAAATTCTTCAACGTTTATATTCCAGACTCCTTCGATAATGTTATGTGAGTAATGTTATGCTATTTAATTGTGATTCTTAATTTCTTTATTTACACGGCAAGATTTTGTTCGTCATGTCAAGACGTGCAGGTAATATGGAGCATTTCAAGAATAAAAAATATGAAGTCTATTATAACACTTATATATTACGTTTTTTTATTTTTCATAAAAGATATAATTATATACATACATAATTATCTCAAATTTTCTATATTTTATATTTATTTCTGATGTGTTGTACAATTTTGCATAAACTGTCATTTTAAATTTCTCAAGAACTTAAACAAAAATATAAACGTTATTGTTCTTATTATAATAATATTATTTACAATGTAAAAAATTATATAATATTTATTTTAAATAATAATTTAATGATTTAGGATTTAATTTTAATATCTGTATGCATGCAATAATATTATTTTTATGTGGCATTGTACAGTAAAGATATAAACTATGTTTAATTACATCCGTATTCCATATTATATCTTATTTTTAAACTTTCTTTATTTTCAAATTTTTtACTGTTTTATTAATACTGAAGTTGGATTTAAATTTTTGAAACTTTCATTAATTGGACATCATAAAGTAGAATTTTGTTTATGAGCGAAAGAGTCCCGGTAAATCATTGGATTCGTGAATCCTCAATTAATTCAAGATTTGAATTTTTTCAATTTTATCAGTCGAATATTTATAGTCAATAATTTTTGCAATCCAAAATTATTGATTAAAAACACCGAATATAGATCGTCTTTGTAATATGAATAATGATTAGTATAGGACGATTTTGCTGAAGTATCTAAAGTCTTAGCTGGACGTGCAGGTCTGAAAATAATTTTGTTGGACTATGAAATTATTTTTAGCTTTGTATCTAACTAAACATTTCAGCAAAATTATTTTTTCCACGTGTGTATGCTTTCCACGGCTCAACGTTCTCCTGTGTATGCTTTCTATGCAACTCCCTCTTCAGTATCGCGTATCTTCTTCAGGGAGTCCTATATATCTCTCGATAGCTAACGAGCTCGTTCCCGTGGACCCACTCGTGGACTCGCGCGTTTGCGTCCGCTGGTCCTGCGACTTAATTAAGACTCAATTGCCTAATTAGTCCGCATGAAGAAGGTGAGCAGCGGCGCGCCGCGCCGCGCCGCGCCGCGGGCTGTCCCACGCGATGAAGTAATCAGCTTTCTCCGCGGCGTAGACGCGCATCGCGACTCCGCGGATGCGCTCTGCTCTACGTTCGTCTATGCTCGCTCGCTCGCACCTGGGGGGgCCCGAAATCGCGCGAGTCGGCCGGGAGAGAACAATGGGAAATCAAGCGCGGGCTTTCCACACGCGCGGCCTCCCTATGTGAACTGGAGTACACACGGCCGCAGTCTCTTATACTGCCTACGCCGCCGCTTGAGCGAATCCCTTGGCTTTGCTCCCCcGACGGTGGCGGCCGGCGACAGGAAaCGGATCTTCTCCGTGGAACGATGAGAAAGGGAGAAAGAGAGAGAGAGCTCTCTATATAAGCACCAGTATGCGCGCCGAAACGTCATCATATATTTCAGCATTCAGTCCAGTGCTCTTCTTCCACGCCACACGGTGTCCGAAGCGTCGTTGTCTCCCGCACACTTGCCACCCACCCCCGTGTTCTCCGTTCCCCGAGCATGGATTTGATAGTGCGACAGGTAATGCGCTAGCGCGAGAAAGGTGCAGACTCGTGATTCGATCAATCGAAATCGGCTGTCAGTTGTTGGGCTTTTTACTAGCTTACTCTCGAGGAAACTTTTTGGATCCGCCGTGTGGTCGAGGGTGTGCTTTCAAGGGGGGTTTCCCGCGCTCCAAGTGTGATCGCTAAACGAGATGGCGATCTCTAACAAGACTGTGAGTCTCTCTAGCAAGGATTAATATCGATATAATTTCGCTGAGTTCAATTTTGCCGTAAGTACACGCGAAGAACGAATTTATGTCAGATACATTGTGTATTATTTTATTCGCGTGTAATCGCAAAAATCATTGTTGTATGTATTTGACTTCTAAACAATGAAGTTGCATCAGCGAAATTATATCGGTATTAATTACCTCGATATCTGGTGGTGAGTAATAAAAGCACGCGATTAATCCCGGAATGCTATCATCGATAAATAATATTTATAATATTTAGAAGTGAATGATATAAATATTTATCAAAAATTAGATTCTTATAAATACAAATGACCTAATTATTAAATTAAAAGGAAAGAAAGAATTAACACACACTATCAAATGCAATCTGCAAGCGGCGTGTTAAATTTATGTACGATAGCGTTCTTGGGTTAATTAGGTAGATATAATTGGTGTTGGGCATTTGCATGGCAGTTTTTTACATAGAACCTCTATTAGAATTAGATATTTAAGCGATACGAGCTTTTAATTTATAGCATGATTTATATAAATTTAACTAGAAATAAGTAATAAATTATTTATTAATTACAAATGAGGTCTAAATCTGAAACGAAAGGAGATAAGAAGCGGTTTGTACTGCACGAAAGTCAGGACAAGGTGAATGTCTTACGTATTACTTAATTTGCGTGAGAATTTGCGTTAGATATTACAAATCAAGAAAAGATATAAATGTATAACAATAGTAAGTTGAATTCTTTTTAAAACTTATATAATTCAATTCTCACTATTGTCTAACTATTTACTATGTAAATTTACGTGCAATATCAGTGAATATACTTTTTGTAGTCGGTTTAATTGTTTAATTGTGATAATATTCTAGGGTTATGAAATGAGATCTAAAATTGCTTGGAGCATAGAATTCATTGCAGTAATACTGTAATGTAACATAAAGAGTTTTTACGCTGAGCAATATATTTTTCAGGAAATGCATCTGACAATGCAATCTTTAATATTTAATTGCTTTTATCATAATATTGTATATACATTTTATTTTGCTAGAACGTAATAACGCGTGATACGCACACACCTTCTTTATTCCACAAAGATTCTTTTCTAAATTTAATAAATATTTATATTGATTAAACAATTGTACAATTATTTAATAAAATAATTATATTAATTAACTATTTATGCAATTATTAAATTAAAAATTTATAACCAATTAAAAAAGCGGAAAACAGGCTTCACTTTAGATAACACGCCAAATTTAAAATAGAGACTTTCTTCATTTCGCTTCTATCTTATTGTTTTCCTTTTATTTCGAATGTAGATCGAAAATGGTATTAATATTAATGAATAATATAAATATAAATTTGAGTATATAGTATCTTATGTGCATGTGAAAAAGGGAAAAaGAAGGAGAGAGAGAGAGAGAGACAGAGACACAGAGACAGAGACAGAGAGAGAAGGAGAAAGAGAGACAGAGAAAAGAGGgAGAGAGGGGgAgAAATGTGAATTTATAAAATATCGAATTATAAATACATTGTATTATATGTACATATGATATTAATTTAAATTTGTAAAAATGTTCAGACAAAAATTTAATATTAATTAATAAAAATTATTATAGTTATATAAAACATAAAATTTTATATAACAAAAAaTTAAATAACACAGAAAAAAaGATTAAAAATATTTGCTTAAATTTAAATTTTATTTATGTAATAAATATAATATATATGATAAATATGAAAATATATTTTAACATTATTGAATAAATTTAAATTGTTATGTAAATCTTTTATTATATGTTTTATATATATTGTGTTTTAATTACATGTTGAGAAAAACTATTGTATCAGAAAAAGACTTTTTTATTTTTATCCGTTCTATAGTATTATGAAACGCAATATAAAACAATGGTTGCAGCAAAAAATTGATACAAATTAATACAGAAAAGACATCTTGAGATATAAAACAATAATATCAAATTTTAATAGTACAAAAAAATAAAAAaTCGGTAAAAAAaTAATAATATCGTAAAGTAAGAAAAAAATTACAAACTAGATATCTTTAATATGTCATATACCTCTCAACAAATGTTAACAGCAATGTTCTCATTAACGCTCTTGTTATTAAGACAATACATTAATTTGCATATTCATACATATACGTTGCATTTGCGTAAAGTGTACTGAAATGCGTTGTGATTAATACGTTGTAATATGCCATAACGTGCACAATCATTGTACACTTGTATATTTACTAAAGCAGAAAAATTTAGTTAACGATAACTAGCGCAGGATAAAAATCGTTGATTCAGATTGCATTTTATTAACAGAATCTTTTTCTAGAAGACGCTAGTTTATAAAACACAATTATTCTAAAGATTTGTTATATCTCCTAAATGTATCAAATTCCATTCGTATATGTTTATACATCACAAATTCTGTTAATTATATATATCTCAATATCATATTATATATAACACAATGTTATACAATAAATTGAGTAATTGCGAATCTTTTTATAATTAAACCACCGGCTTAATCAACGTTGCGACATTTCGCAAAACTAATTTGTGCCCACACGAGATTTTATCTTTACTTAGATTTGGACATTAGTGTGCTAAAGCAGCTACTTAATTATCTGAAAAATCATGCGTATGAAAGACGGTTTCCCGCGGAAAAGTCACGGATTACGTGCCTAAGAGCTCTCTGATTCCTTTACCGTTATGTTTAGTCTTGCGTCAGTTTTTAAAGTGCCAGTGATGTAATATCGTGCACCTTCTCACGATACTGCAGAAACGAGAGAAGAAAAGATAGACGCGCATGAGTCTAATTTCCCGCCTACGCAACGCGCGCGTAGTTGATCATCTGACGTTCTCATCTGACGCATGGAAAGCATCCCTGGGAAGTCATCGGAAATATTTTAGGAACTAATTAGCGTTCCGCTGACAGTAAACCTCGTCGGAACCCGCGTATTACCTCGCTGCATGTTCAACATAACACGCGGGAATATTGTACGAGTTAACATCTCGTGTGGATGATTCCGCCTACATGAATTGCGGAAACAAATTTCTTTTGTTCCCACGATTGGTTTCTTTTTCTGATCACTTTGACGTTAGCTAATACTGAAAAACGATAAATGTTATAAATCATTTTTATAAGCAAAAAAATTTAaTCAATAATAATAAATATTAATAATGATCAATAATAATGAATATTAATAATAATAATAAGTTCCAAAAAATAATACAAAAaTTTGAAGTTTTGAAAAAATTTTGTTCTTTGAAAATTTATTACTTTTATAGCACGCAGATAAATTGACCGGAGAAGTAATTGGTCCTCACTGCATTTGCATTGCTTTATACGTGCATAAACAAAAaTAATTTATGGATGTTTACGTCTTTTATTTtAGTATTAAATATTTATGCACAACTATAAGTAAAAGTGAGCATTTTAATCACACGAGCCAGATCTTAATTTGTTAATATTTATATTTCTATCTTTATATATTGTAAATGTTGATATTATTTATATTTATGCGACTTTAATGATCTAATACATATTTATATACAGGTACTGTTCGCCCTGTTGGCGAGCATCAGCCTCGTGCTCTGCGAGCCACCCCTCAGCAATCAGTATGGCGTTCCCGGAAATTACGCAGGTGGAGGTCATCATGGGGCGCAAGGTGGTGGGAACGGATTTGGTGGCCATTACGGTGGGCACGAACATCAAGATTATGCAGATAATGAGGTATTTGTAATACATATCTGTGTCTAAGTAACTTTCAATGAAATTACACACGCGATTAAGGACAATGTATCCCATGCCCCAATGTCTTCATCATAGCTTTACTGTTTCTTTTTtATCCATCTGCTAGCTTCTTCTTTTGATACAACAATCGATATATAATAGCGCTTGAAAGAAATTTGTAGGAAACCAAAAaTGATTAAAAaTAAAAaGAGACAAAAaTGTATAATTTTTAATTCACTAATGAGTTTTCCTCACTTGAAAATCTTTTTATTTAAAAATTAGGAACTTTGAAAACTGTAAAATATTTTTGAGCGCTACTGTATTTTTTTGATGGTAATAAAATCTTATTAACAATTATTAACACTAATGCTTCTAACAATGCTTAACAATTATTAATTATTCGATGTAAAATATTTGTAAATCATTAAGTAATTTTCTTAAAATAATTTCAAATTAAATAAATAATGTTACAATGTTCAACTATTTGGTAATAACGTAAACGCCGATACGGACATACCGGGAAAAACGTAAACGAAGTAATTCAGAACTTTTACAGGGATGAGATATTGCAATTGTCCGATTAAAAATTTATGCAATACGATCTGACATAACGTGGGATCGATCTCGGCCTATCATCTTTGATCTTCATTCGATGATTACTTCAATAGCTGGTGCAACACGTTTTGCGAAATCAGGCTTCGAATTGCGTGATCGTAATTAAGCCAGACGCTCGTTAAGTAATTAAGCGGCACTTTTTTTATCGATAAACCATTTATAAAATAATGCGAAATAATTAGTATCAATTAGCGTGAGAGAAACACTTTTACCGCTTTTGTAAAGCATGTCGTCGGTGGCTTTCGAGGTTGCAATTTTGATTCGTGAATTTCAAATGACTCATGATAGATCGATATTCCATCGATGGTTTTGAGGATTGCATAATCTGCAGCATTAAGGAAAACGCATCTTACGTCATCGAGACAGACGTTCTTTTGTTCGGAGAATACAGTGTGCTGCTTTCTAAATCTAGATACCTGCCTAATGTATACGTATCGCCGATTATTCCGACGGGTCTTGCGAAAACGCGCGGCACTCCCGAGGTCAAAGTTGAACACTTCAGCTCTAGATTCGGTCATGTCTTGGAAGTAACATTGAACTCTTCGGATAAAGAAAGGTCTGGCCTCATTACGCAAACCTCGTCCGGAGGAGCGCGCGCTCTGAGCTTGAGCTAACTATTTTCTGAATGACCTCGCCGATTTTTTTCGtAGGCGGCGAGTAGGATGATaGATCCtGGGATATTTAACGTTATATTACATTACGATCGAGATGTTTCTTTTATCTTTCGTAATCTTTCACGATTTGCAGCCGATATCATTGTGAGATATATTACCCACTTACTTTAAATTGACTTTGAGGTATCATCATTTCTCACAACGAGACATTTATTACCAGATTTTTAGTAGTAGTCATCGCCAAAGGAGATGTTTGAGAATTGTATAATAATTTATAAATTCAATCGCTAACAGTTAAACAATGATCGTAAAAGCGATATTTATGACACGAATAATGTAATATTCAATATTAAAAAATGTTAATCTGTACGTAATTAAGAGAACTCATTTGTTTTAAGACATCTTAATGATAACATTTTTCAATTTTTTTtCTTTTATTAGAAGTGTATATTATGAAGATATTAAGTCAAATGCAGTTTGCAGAAAATTTAAATTCCTTGCTGGTTTTCTTACATCTTGAAGAAAAAGGTGTATAAAAAAaGAGTTAATATTTTATCAGTTAACTGGCATAGTAATGAGTTTATAGACACGTTCTAATAGTTCGTCTTTTTTAAGGGAAGCTCACTGCATCTCCGTATCCCTTTCTCGCAAAAaCGAATCATCCTTGCACAACACGCCTCGCAATCAATCGGGTTAAAAATGCACGATCGAAAGACGCTCGTGCATATTCCGACTCACAGCTTGCTACTCATACTCGCACATTGTTTGAACACTGCGGGATTACGTTAATCGAGGATCGACGCATCGCGCTCAAGTGTCTCGCGATGCTACAAATTCGAGTCCGAGAGCGAGAGCGTGGCGCAAACGGGGATGATGTAACAATATTAATAGGGTGAACCGCGACCGCGGGCATAATTCACGGTAAaTCGTTATTGCTGGTTAGCTAATCGTCCCGGGGATCTGCGCGTTCGCATCTCGCGCGGATCTGCCCGTCGGCGAGGAGCGAGCGAGCGAGCCCGCTGCTGGTGATAGTAGCTGATGGTGATGGTTGTGTGTGCCATGAGCCAGATTAAATCGCGGCAGATTCTCTTCAGCACCGTCGTCCGCTCTACTTTGCCGGGACGGAGGAAGGAAAGCTTGTCGTCCTGGCTTAGAGGTTGCGCCATTGCGCGCATTAATAATGTGCATCCATTCGTGTTATTTTTTCACTTATCACCTTTCGTCATTTATCTCTGCATTTTTACATCCTTCATTCTTTACTCTCTTACCTTTCTACCTTTCGTTCATCCCACCACCTTCCTTCCGCGAGAAGACAAGGGGGGAAAAAGAATAGGGAATACCGCGATGACCCGTATATGACTCTGCTTCAGCCCAAGGCCTACGAGTTCGGCTATTCCGTGAAGGACCAGGCTACCGGAAACGATTTCGGTAGACAGGAGACGAGCGACGGCGAGACCGTGCGCGGCGAGTACAGAGTGCAGCTTCCGGACGGTAGGACGCAGATTGTCACCTACACCGCCGACTGGAGGACCGGCTTTCACGCCGACGTGAGATACGAGGGTACCGCGAGTTATCCAGACCAGTACAACGCCGGATACGGAAACGCTGGTCAAGGTTTCGGCTACCAGGGAAATCAACTCGGCGCTGGAGGCAGCGGATACGCCGGAGGTGTGTAGCATAGAACGTTTAACATTTTGCTCGTACTCTTTCAAGCGTGATGGTACATCCGTGTACCATCCACGGAGTATTCAAAGAATTATTCAGCACTTAAAGACAAATAATATTCACCAAATTAAAAAAaTATCTAATCAATATGAATTATTGTCAATCAAGATGGTCGACAAAAGCGATCAATTAAGATTTTGATAATTAAACAATATATTTAATTATAATAAAATTAAATAAAATATTAAAAAGGGATTGTCGATTGTATTACAAAGAGTAATATTTTAATATTTTAATTAATCTTATTATAATTAAAAATATATTGTTTAATTATGTTAATTTTATTTGATTTTATTAATTTTATTTGTTTAGTAACAAGAAGAATTAATTTATTATACGAAAAGAAATCAATGATTTTAATTCTAATTGTTGACGAGATATCGTTTGAACATACCAGACCAAAATCGTTTAAATATGTTAAATATTtCGTTTTTTTTTttCAAGCATATTCTGTGTAATTTTTAATTATTTCTCAATGTTATAAATCAACAGGTAACCAGGGCGGTTACAACTACCCATCGGGCGGTGGACAGAATTTCAACGCCAACAACTACCAATTCGGCTCCAATGCCATAGACAACAGTTACAACAATTTCGGTGGGAGGAATAATTACCCCGGAATACCGTCGCCTACGTACGGTCCTGCTTTCCATTAGAATACATAAAAAaGTATTATATAGGCTATACTGATTCCGCTTGTGAGAGCAGTCTTCTTTCCAATAAAGACATTTTTCATAAAAAAaCTTTCTTATTTGTACAAATATAAACCATCAAACCTTGGTAGCTTGGTAGCTTATTGAAGCGAGGAGAAATTGCGAAATTTACACTCAATCACTCGCGTGCCTTTTCTCATTACTACCAATCGCAACGTATCTTTGACAATTTCGTAATTTTCGGACGACGTGAAAAGCGACGACAAGCAACGTGATGTATCAAAACGTTGCAACATCAGCTAATGTATGTGACAGACATCACACTTCCGCGCGTTGTAATTATACAGTTGATGAGGGAGTATCTTGATTATTCAACCCTGCCTACTGCACTCGCCCTATGTTTACTTCGCATCTCTCGTAGGTAATCTTCCAGGCGAAGATAGAGACGCCCCTTATTTGTCTTACGGTTTCTCATATGGAAGAGATGAGATAAAACTCTTTCCTGTGAACAGCTCTATTCTCTCGAGGCTTATGCTGCATTTCTCTCTCGTGCCGTTCACAAAAGAAGTTTATACTATACTTTCCTTTCTATTTAAGAAAATACATTCTCCAAAGGTATAAAGTAATATGTAATGTCATTATTATTTAGCAAATTTATGTTAACAAAATTATCACAAATTCCAAATCTGGCTTACAGTTCTTTTGATTAAAAGAAAAACGCTTTTTAGTGTACAATAGATTATTTGCGAAAAAAAATGTGCTGCAACTTTTTTGTTTTATTATGTCAAGTTCAGCGTCTGAGTAACTTGTAAATACATCGTCAAGAGATGCTGCTGTTTTGCATTATGTCATCAGGAAGTTCACGTGCCCGTGGAGATAAACTTTCTCCAACGTGTAACACTTAAATTGCACACTGCAAATTTCATTAAAATCGCAAGCACACATTACCACACGTAAAAGTATGTGTGCCATTATCATTCTATATGGCCATAGCATTTTAATAGCGCAGTAGGAATATAAGATAATTTCGCAAAATCGGTTTATTTAATCTGGATATGAGATTAAATAAAGGTATGGATCGTTAACCGCAATAACGTAAACTTCGAGCTGTCGCTACGGACGTTTCTTTATTGCAAATAGTACACACATGCATGTGTGCTTGTGTAATATAAAATGTCTTAATTATACTAAAATAAAATTGCATTTAAATAAAAAaTTTTATATGTTCGTATAAATAACGTAAATTAGAATAAGATTTTGCAAAACAGAATATCAAACGTCTTTATAAAATAAATAATAAAATAAATTGGACATAAAGTTAGAACAAAAAATAAAATAGCAATCCTCTATTAATATCATATTTTTAATGAAATAATAATAGAAAATGGTAATGGATGCAAAAAGCTTGGCCGCCTTGCTAAAGATTTTTCAAAACGTTCTTTGCAAGAATAAATGTTCGTTCTTCATCACTGCAGATTTATCACATTTTGAAGCGTGACGCTGTCATACGGAAGTAAAGGCGAAAATAATCGCACGCACGCGGATGTCCTCATTCGGACTGTTGGAAACTTCAGGCGCACACGGATGTCCGCAGATCCGGGCTGTTGCAAATTTGAGGCGAATGGGATGGTAGCAAGATATCTAGGACAATTGCGTACGCGCGGAAAAAGTTTGCGAGATTTACGAGTTCGCCCGCGAACGAGCCGGGGATATTCCGACCGTGTTTATTGGTCCTCACCGGAGAAAGTCACCGGGTGCATTTTTACCCAAGTGCGACTCGCGTGAATCCTTAGACCGATTAAGAAACGGTTCGTTAGGGGATTCCTGTTTGATTTCATCTTTAATGCCCGCGATTGCTCCAATAATATATTTCTCTCCTCGCGAGAATCCCCTTCTAATTGACTCGTGTGTCGAGAGTCGCGCGTAATGAAGGAAGCGGCCTATTAACTCCATGTCACTTCTGAATCTTTATAGAATCGAATGAAAGAATACAAAATCTTGCAATATCGCACACTGATAAATTTGTTGTGTCGAATTATAGCCAATTTAAGTTACTTTTAATCATTTTTATAGGTCGCTATTTCTCCTATTCAATACGTCTCTAATTTATCTAAAACATGGAGTTAAACAATTTAACTTAAAAAATATTAAAATGTTTGACAAATTTAATATATTATTTATTAGAAGCATACATTAATATGCACGAGTTGCTTACTTTAAAACTAAGCAATTCAATGACAGAAATAAATTGATTAAATAAAACGTTGTTTATTTTAACTGTACGTTTTCTGTTAAAATAATAAATTTCAAATAAAAATAAAAaTTAAAAATAACAAAATATTATTTAACGCATGGAATTGATTTAAATTTAATTTTTTAATACTCAATTGTGTAATAGAGTTTATTAAAATTTACTAAAATTTAaTAAAATCGTTATATATAAATGTTTATTTTTATATTATTTAACACGTCTTGTTTAATATTTAAAAATTTTTATTTAAAACATTATCTAAAACAATATTAAACATTAAAAAAAaCAAACATTATTAGGAAATATAGAAATGATTTATAGATTTGTAAAAATATGCGCACCTTAATGTGATTTAAGGTCATTAAGTAAAAGCTTATATAAATTATTTCCATATTTTTTAATAATTTTTTTTTTtAATATTTAGTATTATTTTAGATAATGTTTCAACAAATAATGTCTTGTTTTGCTCTTAAGCTCGTTTTATGGGATCTGGAATTTATGAAGTAAGCAATTTTCTGTCAATCTATCTCGTATAATAAGTTTTATGAGTTAAACAAGTCATAAATTATCTAGCAGTGATTATAAATCAATAGTGCATAATCGAATAATATCAGTAATATCATAATATTGTAATTTCACATTTATTATAAATCTAATATTTATTTTAAACAGTCGATTTTTTAATATTGTTTAATAGTGTCTTACTTTCATTTTCATTTTTCTCTTTGTTGCAACGACATCGAATACTTTATGTACTCTTTTGTTTTtGTTTTTTTTtAATCATTCTGAAAGATTTCACGTAAACAGTTATTGTTGTACTTTGAAACTCTTGGTAAGAAAAAATCATCGGAGTATCAAATAACTTCTCGACAGCCCTGAAATGCCTTTAGCTTGAATAAGAATGCAAGCACACCTTTAGAAACGAATGTAGGCATAATGGACTCGAAAATAGACGTCGAGTTGAACTACTATTTCATGTTCAGGCACCTTTACGCGAGGCATCCAGACACCAATCCCCCATCCTGACTTACTTCACATACGTGGAATCTTGCTTCTTGAGAGGTGACGTATCCAAGATACATCAGATCTGATGTGGCTTGGCCACGGACTGAAGAAAAGAGGCAGAAGAATAAGCCACGCATACATATCCACGGTGCGCGTGTAGCACATGCAACGAGCCTTCCGCATCGCGTGGAGTATTGCGTAATGCCGTTTATCCCCGATTACAGAGCAGACCGCGCATCCGCGAGCCTTCACTCACAGATGAGTTACGTGGCCACCTATCTGCACCGCGTGCCTACCTGCCGAAGCCGGGGCATTCGGCGCCGATCCATAATTAGTAACAATTATGCCGAGATTAATTAAGCATTCCCGATCGCTGCGCGTCGACGAATCGCGTTGCCGCGCAATTGCGCGTGTTTTCAGCGAAAAGTCATATTGTAAATTTATACGCGATCCACGAGGAATCAAAATCCAAATCTTTAAATGTGGAAGCTCACGAATATAATGTAACATGTACGAGAGTAAATTCTCCAATTTATTACGTTAATATAATTTGTCTACGTTTTTATTATTCATGTCGCTTTTGTATGTATTTGGACAATATCGGTAGAGGGAATGAAAAATTACGTTAGTGTAAAATTTGCATTTTTGCGAAACCGACACGGCGGTTTTAGGCGGCGAAAATAAAAGAATTTAACGAGATTGAACTCTCTTACTCCAACTTTTGTATGCGAATCATTATAACGAAGTAATGTGCGCACAAGTAGGCTGAGGTAGGATGATTGTGATGAATGGAAGGATGGCCCACGCATATGCCGGAATCCGACAGTGTTTGTGAAACAGCTGATTAATGTGGTGATCGATGCGTCCGAATTAACCTTATGACTCGTATCGAATTTTTTCGAGGCCTTGATCCGTCAAATTGTCCCAGGGAGAAAGAACAGACGTTACTTCGCAGTAAAAATTTCAATAAATAAAAAATAAAACACGCATTCAAGGGCCTTAACAATAAAGGTCTGGTAAAAGATAATTTCCAGAAATTATATAATTGTACAGATTCGGCAATTATTAATTTCAGCTTGGCATAGCGTGACGTGCATCGTATCGTAGTATTCTTATTCTCATATAATATAATAAGTCTTATGTAACGCGTAAAATCGCCCAAAATTGTTAAAACGTGCGGCGAAAGGTCATTACGTATTTTCTGGATACTTTGTTCCGCGCTGGCAAAATTCGCAATTTCGACGAAATTACTGCCGGCCGCATGCATATCTGATTTGTAGTAATATACCGAAACGACTTTGCCATAAAGGTACCATCATTATGTTGTAATTACGAGGTCATTACTTGAAAAAGGTACTTGAAGTTCGTGGTGTGCAGTTAAATTCGTGTTTCAGTTCACCAATCATTCACAACTCCGGCAAGTCTGTAAATTGATATTCTTAAAAAGAAAAaTTACTTTTTAAAAAAAAAAaGATAAAAAGGCGCAAATTGCGCATTAAAATATACGTTTAGAAAAAGTAAAAACAGGACGTTTCTCTTAAAGCACATAAATGTCATATGTGTATTCATTTTAATGTAAAAAATAATCTGCAATGCGAATATCACATTTGTCGTTTTTTGTAAAAAGTAAAAATATACAAATAAAGGAAAGTCGTGAATATACTAAGCCACCCTTCTTAAAACGGCACCCCCGTATTTTTTGGAAACTGAACTTTCCACTAATAAAATCATGATCTGTTTAAGTAATTGAAGAAATAAAAACCCATAACATAGTTCGTACATTTTCATGGCTTTTTCCTATATAAAATCTGTTAAAAACCAATTTTTGAAAAACAAAAATAAAATTGCACAATTTTCTCTTGCAAATTGCATAATTAAAACAATAATGAGTATATTATTGAAAATATTATTGAAAATAGCTCATTTCACATGTTTGTAGTTTTCCAAAACTGTTTTGTTTATATTTTTCTCTTTCATATTTTCTTCATAATGCACAGTTTGAGACGTAAAATTGCTGTAGCGAACCATCTTCTCTGTGAGAACAGACAATAATTATGAAACTTTCAACTACAATATTGACAGATGTTTGATAAATTTTTTCATGTTTTTTTTTAGTAGTTCTTTAATAAGTTTTATAATTCAAGAAGAGTTAAGATATGAACGATATTATACAAGAACAGCACAACCAAGAGAAGTTGCTATATTTTTATGACATTACGGATTTAATTACATTTACATACAATGACATTTAAATAAATATTACCTTCACTGATTCTTATATTGATATCGGTATTATATTGATAGTTTTTAATTTACTTAATTTTACAAAACGCGTAGCAAATTTGGCATTGAGCCGTGTAAGGTAAGACAAGCAATTGAAAATTGCAATATTTCTAGTATGTAATGTTCAACAACAGAAAGTATTTATATCGTATGAATTAGAAATTCAAACGGAGTAAAAGATATTTTCACTAATGCGCGATATGGATAACAGATATAATAACAACCGCAGCAACGTGCATATTAGCAAGATTAGTATGGGTGTTACTTCACATTGTGTTTACCATAGAGATCTTTCTAAGTACATAGCACAGTATAATGATAGTAATAATATTCGTAAATCATCATCCATTAGGCTCTGTATTATGCAGCGCATAAGATAGCGTGCTTATTGAATTCATGAATTCGCGAACCGTATCATTAGAAGAAAAGTATCTTATACCTTATGTATCTACTGTAATATACTCTTCCATAATGATATTGTTCGAACGAAAAGGAAATTAAATGCTGACAATTACCAGAAACATAAAAGCAATAATTACTCCATTGACGCGAGCGCTAAATTAATAAATCTCGCCAGATAAACACATTGAAATTTATTATAGATAATGTTGCTTCCGACAGTAAAGATACTTCCGACTTGCTGAAATATATTTTTATCGATTGATCAATTTTAAATTCTTTTTTTTTtACTTATTGCTGCATCGTATTATGACAGCAAAAGTGAAAAATTATGTAAATTATTATATAAATAATTATGTAAATAATTTATATATAAAAGTAAAAGAATTCTCTCGTTAAAATTTTCTGCCCTATTATCTCTCCTACATTAAATTTATGTATAATTTAATCTGCACGTTTCTTATGTTCCCAGAAAAAATAAATAATATGAGTTGATCATGAGTTGAGATGAAAAGAAAaTCTTTGGATTTTACCAATCCATAATCAAACGTGTAAAATATTTAAAAAaTTAATATGTTCAACGCCACACTATGATTTTTAAAAAATCACCTAATTTTTGTAATTGACATCTGTAATTGACATTTGCAAGTGACGTAATTCAATATAGCTGCAATAAGGAAACAGAAGTCAAAGTCTCGAATTAGCGAGTGCACGTAATAAATAATAACCCATTGAGCATAAAGTCATTCCTACCATGTTATTACAATGATATTCAATAACATGGAACGTTTTTCAAATATGTCGTATTTAATGTTGAATACAATATCAATATAAACAAACTTAGACTTGGAGATGATATTTTTCAAATACTTCAACATTCGAAAGAAAACATAAAAAATTAGAAATCTTTTTAAAATGTTTATACAATATTATTTTAAAAATACATATAAAATCAACAAATGTTTCTTGCTTACTGGAAAATATTATTGTATCGAGATGCCAATGCGGAATTGATGATACCATGATGAACTGATGCTATGCGGAACCGAAAATGTTACGTTGCCAAGTACAAGTATGTATGTAGTTAAAGGAGATTAAAGATATCGACAGCAATTAATCTGAAAGGCACATGCAACATTCTCGATCGGGACGCCCGTGTAAAATATTATATAAATCGTGGTACACGCCATTTCTATTAAAATTAACACATAGAAAGTAAATTAAGATTTTATCATTCAGTCAATTTTCAGGCTATTTTATTTCAATAAAAATATAATAAAATAGACTTTGATAATAGATAACGGCTCTTGTCAATTAAAAGAAATAGAAATCATCCATAAAAACGCCAGTAACCGGAAAAACAGAAATAATCTAAAATCTCCTTTTCTGGCAGTTGAATTATCATAATCCAAGCAAACATCGTACTATACATCGCATATTACGTCCGCGTAATTACTACTGTACTAATCATATCGTCGTGAAAACGATGTTATTTTAATAACGCTCTCAGCAGGTATACCAGATTGTTTATTAAACTCGCACGTGTTTACCGCGAGCGTAGGCCTGAGAATCTCGTACGTATGCACAATCGACAAGCGGCGTTTCGTTTCGCGCTCGTTATGATGCATCTTCGGAGCATTCTCGTAACAGCGTGGCCAATCGCATACCGGGGCACGTATAAGGAACCCGGCGTCGAAAAAGGGATCAGGCAGCCGCTTCGCGCGTGATACGTCAATTTATCTGCCGGCAGCTAAAATCGCGTTGCGCGATACACGTAATATTTATTCTCCGTGACGAGTATCTGCACGCGCAACCAGACAGAATATCTTTGTACCCTCCCGCTCCCCAAACCTCCCCGCTATACAGATACAGGGCGAATTTTATACCGCGCAGCGCGCGGTCTTGTAGCAGCTCGCTACGGCTGATTTCGCAGATGCGGTAAAGTtGCACCACCTTCAACATATAACATTGACAACAACGAGCGATACCGACTCTGCCTAACAAATGAAGCGCTGAGAATGAGATAGGTCATTGTAGACCCTGAACCAGACTCACAAAGGACCGACTAAGTCAATACACTTTGCCAAGACGTGTTTCTTAGCTGTCTCTATAAGAACTCCGTCCGGAGTAGAGTGCTTGCCCAACGTGTAATGTTGAAACGACATTGAATAATACTAATGATATGGATTGAATGATATTGAATAATGTTGCCGATGTTATTTTGCGCATAATAGAGAATATCGAAATGCATGCAAAATATCGGCGAAATAAATCGATAAGGATCGAAATATCTGTGCCAAACGCGCGCGACTCGCTTTCCCATGTAATTTCCTTTGCATTTGCAACCCGTTTCGCAATTTTTTATATGAAATGTCTGATTCTTTACGTCATATTTCTTGGGGCGCTAAATATCTGAATTACGATGTGTCTCCATTTGTCTGAGAGCTCTTAAACAAATTAATTAACCCGAGTGAGGTAATATTTTTCGCAATAAATTATTTACAGTTTTTAAGATGCAAGTACTATTATCATTATTAAATTAACGATCAATTTGATTTGCGATATTATTCCTAGTTTTAATTTAGAATTGAATTTAAAAACCGACGGTGTTCGGCGTGCAGTTTATAATAATATTGAAAATGTTTTTACCAGATTGGATAATAACTCATTACAAAATTAAAAGTTAAATAATGAAAATTTTAAATAACCCAAATTTTAAGTTTAACTAATTATTGTTGCAACACATAAATTTTAATTTATTAACTTTCTTCCTAAATTAAAAATTTGCCTACGTAAAAGAAAAAAAATTATTAAAAAATGCAGTTCCACATAAAATGTTTCTTTATTATTTTATGTAAACTTAATTTACAAATAAAATATTAAATTTATTCAATGATCTGTATTATTGTTTTAAATAATCTAACTTATAAATTTCTAATTTATAAATATAAATAATATTCTTCAAAATTAACTTTAAATTTAACTTGAGTTAATAAAATTGTCTGGAAAGAACTCGATATTGTTTAACTGACTCACATGAAAAACACCTTAGGTCAAAATGTTGGAAACAAGTTTAAATCAGTAAACAATTTGCCAGTTTGTCAACTAAATTTAAAATTATTATTAATATAATCATAACTTTTAAGTAGTTAGTTCTTTGTTCATGTAACTATTTTTCTGCTTTGGCAACAAATAAAAAACAGTGATACTTGATGCTACCGAGAAAAGGTTTTAAATATTAAAATACTACTATCTATAAGCATGGGGTTCTTTATACCATCTAAAACTATAAGAAATTAATAAATTTCCAATCAATACTAAACATCAATTATATTATATTTATATCTATGTTGAAATTTCGCACTCAAAAATGTAAATATAATATAACACGTGTTGTTATATCACATTTACATTACTGAGTGCGAGATTTTAACTGATGGTCCCAGTGCCAACTGGATTGTATATTTATAGATACAAAAATTGCAATAATATTTTATAGCCATGGCTGCAATGAGAACGAAGGAATTAAATTCTCGAATTTTCTCGTACAATCGTTAATCGAGCAATTGGTTTCATCTAAACGGCTGCAAAATCCCGGAATCTTCGTTAACGATCGGCGATGCACATTGCATCGATCGATTCGCAAATATATACCGGGAATATCGTAAAATTAATCGCGAAAATGAATCGCCGTATTGAGTCGTCACTCGCACTCGCGGCTCGGGTGACGTCGGATTACTCGTAAATTTGTTAAACGTTTGCATAAGTCGTCGCCACCGAGATTTATGCTTTGCGCTTCTACTATACATCTCTCGCGGATCGCGGGCGAGCAAGCGCCTCGCGCGATCTAAGCGGCGCGCCGCGCCGCGCGAAGACGTGCGCGCACACCGAATAGATCGGATTTATATCCCACACACTCATCCTCGCGTCGCGTCTCTCCGTACCAACACTCCGATTACCGGCAGGCGTATTTCTTCACATCCACCTTTCATTCGTAACTACAAACTCGGTAATTGGTTCGATACACTTCGGGATGAGATCAGCGAGCGCGCGCGCGCGAGGCGCCTTTTTTTCATCCGATCAGACGGTTCGAAAGTGCGGCGTCGGATTTCGAAGGCCGTCTCCTCGGAATCGAACTGGCCGGCTAGGGAGGTAAGGGAGGTAAGGGGCGGCCGGTAGATCTATAGCGCTTCCCTGGCGGATGAGAAAATGTGTCGAGGATCGCGGGGAGCCCGCCGGCAGATGCGGCACCAGCGAATTTTCCTAGAGCTGCCTCCGCCGCCGCCGCGGCACTGTGCAATCGCATTCTTGCTCGCGCGCGTGCAACGCGTCGGACGCGTTCTCGGCCGCCACGTGCCTAGGATTCTTTTTATTGCGCGCAGAGAGCACGATGTCGAAAATGTATATGTCCGTGCCGACGGAGGCCGATTGCCCAATCGTCCGACGATGATTCGCGATAGTTTGGAGAAGCTCACGCTCGCCTCGCGCGCGGAAATGTTTTCTTCTTTTTtCTTCTtCTCTTTTTTCGGCCTATTACCTTCTGACAAGTTGATTTAAGGATGTTTTGGCTATGCAATACGAGCTACAAGTGTTATCGAAATTTCAAACCTAATCCCCTGTGGCCTACAGCGTAGAATATTGCACAATATCTCAATATTGCTATAACATTGTTGAAATATTCTGCAATATTCTGTGCTATAGGGAAAAGCTTCTCTAGGTTTACTCTTTTCCTTGCTAATAGACAATACAAAATTTTCATCGTAAATGCTCGAATTCTGGTCCTTGCAAAATAGCTTCAAAGAAGAAGACAATGAAAAATTTGATTTATAATGATTTTTGCAGCGAAAATTATTATATTTCACTGCAGTTTTAAATAAGTAACTCTTAAATGAGTAAGTGAATCTAAATAAATTTTTGTACGCATATTTGTTAAAGTTTTATTAGTATATATATATAAATTTTGATTTAATTGATAATGCTACTTCTCAAATTTGCAAATAAGTACAGCAAAACGCGATTTTACATGAGAATTAGAAATAAAAAAGTTAAATAACTTTTAAATCAACAAGTAAATTGTGCTCAAATTTTACAGATACTCAAACGTAATACTAAAATATTCTATAAAATTTTTTTTTtGATAATGTTTTAAGATATGACTTATGCATCATTAATTATATCCTTTTGATTTCACGTATGTAATATGTTTGAAAGTCTACAGGAATGCCGACGCTTACATTCTTTTTtTttAGCGGATATGTATCTCTGCGTAATACATTTTACATAGAAATTATTCCTAACAAAACCGTGTTATCGATAAATTATTATGGAAATTTAAACGTGTACAATTTTAAGCTCTAATTTTATGTGGAAATGATAGCATTAGCTTGAGATATGTTCCTAACTTTGTGCCTTTTACTACACAAACGTTAAAGTTACGCTCTAATCAATTCTCCTTAATATATCCCTTTACAATTCTCTCTAATAGCCGTGCAAAATTCTTATTCTATACATAAGAAAATGCTCGAGTAATCATAATTGCAAATATAAAATATGTCATACCTTTCACTTTTTTCGCATGACTTTTTTCACGCCCAAACTATCGATTCTATTCAATTGACATATAACATACATCCAATATAAAAAAGTAATATGACGTTATATTATCAAATATAACGCGTCGTATTATTTATAACATAATATAAAATTCCAATTCCGCTCAAAAGTGTTAGGTATCTATAGCAGCGCTCAAAAATATTTTGCAGATTTCAAAATTCCTAATATTCAAATAAAAAGATTTTCAAGTTAAGAAAATTCATTGATAAGTCAAAAATTATATATTTTAATATTTTTTCTTAACAAAATAAACTTTATATATCTCGAATATTTGAATAACAATCATTTTGAAAAAAAACTATTTTGAAGAATAACTATTTTTTTTtGTTCCCTACAAATTACTTTCAAGCGCTATTGTATATTTTTTTCATTAACTTTATTATTTCCTCTTACTTACTAGTGTCATGTATAAATTTAAAAAATTCTTGAAACATAAGATGATTCACAATTTAATTTGTTTAAATCCCTCTAGTTAATATTTAAAATATATAAGATGCCTAATATTTTTTGTATAATAAAAATTTTAATTATATGCAATATCAATTACGTTTGTAATAATTAAGGTTTTCTTATTCAAACCTCAAATATATAAATATGTTACAGTTTTTTTAGAAAATGAATTCAATCAGTAGGTAAGaGAAaCTTCGGGCTTACAATAGTACAAAAAGCAAGTTACCAATTCCGTTTATTTATTTATGCCGAAAAAAACAATGAAAAATTATTTCAAACTATCTCTTTCCTAATATAAGAGAACCAATTGTGAAGTTTTATTTAAATAAATCAAGTATTGCAATAAAGAAAGGAAAAAATCTAATTCAAAGGAAAGATAAGTTTTCCGAGTGTTCTAAAATTCGTATTAATGTTTAATAATTTCTTATTAATGTTCTTCAGCTTAAAAGAATGTAGAGTGAAAAATCGTAGAAAAATCACTCAAAAAATTGCACGGGCTCAATTCTCATTTTAAAGTAACGTTTCGCTCAATCAGATTTAGAGAGTAATTAATAATAATTTATTATAATAAAATTATTTATAAATCAATGTATATAGAGATAGAGTACATTGACTCATATTTAAAACAGTGAGACACAGTGACAAGTGTGTGAACATTCAATTACAATTTATGTAACAAACTGTAACAAAACACTCTGCATTTAAAATTTCTATATTGAAGCAAGTTACATTTAAAATTGTTCTGTAACAGCATTTTGCTATTCGATCTTCGCAAAATAAGTTTAAAAATATACAATTGTATATATCTTTACAATTATACATATCTACGATTTGTTTTTtATTTCTATTACGTTTACATTAATTTAATATCAAATTTGTTGTGTAACTTACAGCGTGATACGTGCCAATGTATCCTTTCGTCGATCAAGTTTGCTACAATCCAGCATGTTCGTATTTTACTTATTACAAAGAAATTATTATATCATGTACAGAATCATTCCTGACATGGAAGCAAAATTCTCTCTATCATATTAATACAGTTTAATCATAATAATAAATTGTTTAAAATGTCGAATACCAAAATTGTGAAAACTGTAAATACCAAAAACCTGTGAACCTCGCTCTCCCCTAATGTTCTAGACGTTCTGAGCAGTGTGTTTCATTAATTTAACATTCAGTCACGCTAATCCGGTGATTCGGATTTTTTCGACACGCATTTCTGCGTGTCGGAAATCGATTTCTACGCGATGCTCCCGGACGCAAATATGTTCTACCGTGCAAGATAACCCGATCGAGAAACCGAAAGTCACGTGCGTAGCTCCAATTAAAATTTTAAAGCTATTTCAGTCATCAACGGGCTATCTATTCCCATAATGCATCACACGGAGTGAAGGGAAGATGCGCACCTCTCCGCCTCCCACACCCTCCCACAGAGTGCGGTCGGTCATTCTAACACGCCAGTTATTACATGGATATGCAGTACGAAGGATAAACTGTAACAAAGGGTTTGCGTAGTATATAAACTCCCCGGAGAATCATCTTCTCAGTTCGCTTCGTGTCTTCGGTCCTACAGCAATATGAATTGCCACCAGGTAGGCCACCAGATAGTATCGTGGGCGGACCATTTTTTCGCGAAATGCACTAGTCCGCTAACGTGTTTTACAATAAGTAATTTAATAATCCGAATAAATGTATTCTTGTAAATGTTTCTAACAATAAATTTTATTATAGAAGTTTACTTATCAGAACTTACTTTTCCTAACAGCACAGATCTCATGCCCGTGGTATGCCCATGGGAATCCCTGGGATGTCCCTGGGACATCCCCTGGGCGTCCCACGGGTGTCCCGTAGACGTCCCAGGCTGGAAAGTGTGCTGTTAGAGTTGTTCTGTACTCTCTAAATTCTTTGGAGTGGAATCCCACTCTAAAAGTGTAAAAATCCTGCCAGTCTTGATAAAGAGTGGCAGTATTTTCACACTTTTAAAGTGGAATTTCACTCTTTTAGATGAAATCCCACTCTAAAGAATTTAGAGAATATCATATCAATTTTTATCGTTTATTACTATATTATTAAATTATTTTATTTATTTTTACATTTGTTTTTTTTTtATATGAAAGCTTAGAATATTTAAAAAAAaTTATTTCCTTTATTAGAGCATTATTTTGACTAAGAATCATTAAAATGTGTCATCGGGACCAGAAAATTTATGATATATCTTCAATGACTTTTAATACTATTCCCCTAATTTATTCGACAATTATAAATTATAAAATACCTCAAAGATAGTAATTTTTATTACGTTTCGTTATTTTGATAAACAATAGAAAATTCAAAGACAGCTCTTCTCTTTCTCGCATATAAAAAAAAAaGTACTAATCAAAGGCTCTTTATAATCGATCATTTAGCCAACATCTCTAGTATCTATAAGTTGTTATATAGCTGCCTTTCTCTCTTATTATTCTTACGAACAAAATATCTTTGATAAAGCATGAATGAACAAGCAATCGTAACAGACAGCTTTTAAGTTTGCTTGATAGAAGAAAATGGAAGTAGTTATAACAGGAATAAATTGCAACAGTGATCGCTAATCTGGAATCTTATAACGCCTGTGATGCGCCTATGCAACACGCGATTTGCAATTATCTTCCATTGTGCCAGCGATGACTCTCAGCTTGGTGACAACGCGTCACAGCCGTGAAAGGTGCGACATTTATGACAAATGTTGCAATTTATCCCGGTCACAAATACAGTTCTTTTCTTTTCTTACATACCGCAATAAACGTTGGGACAAAAGTCGATTAAGAAATTTAATAATCAGGTGAATAAACTAAACTGAGAGATGAAGTTTAAGATAAGAGTAAAGAAAAATATCTCCCTATGTATAAATGTATGTGAGTTATGTAAACAAATATGTGAATAGGCACGTTCATGTATAATTGGTAATAATATGATAAAATCCTTTTCTATAACAAGTAGTGTAATAGTGTAATCGAGATTCCGCGTCGATAGAGCGGTATGGTTTTCCCTCACTACGTGATGTCAAACATATAACCGCATATAACGGAGGGATGCCTGATTGTGCCCCACTTTCCCTCAGTAACGCGCGATTATCGCAGCGGACACCGCAATGTCCACCATCTCGGTCCCGCAATACGTCTCGGTCATATCTGACCCATCGGCTTACACGCTCTTCCTTCGGAATAAAAAGTTCCAGTGAGTCTTCCAAACCGGAAGTCAATGATATAATCATTCTCTAGCAATTTCGTAATACGCAAACAACTTGTCATCACTTCTAATGACTTTATGATCAAACGTTATTAATTTTTtCACAAAAAAAaGTACTTTAAATTAAATATTATTAATTTCATCGAGAAATATCGCATTGATCCTAATTGAACTGCCTTTATTATCGGCACAAATGTATTTTCGAGCAAAAATGCGTAGTAAATATGCTTATATATTAATGAGGTTTCGTTATATAATTGTAATTCACTTACCCCGATCTCGTCGAAAAGCCACAGAATGTCTTCTCTGATTGCAGTTGGCCAAGCTGGTCTTGGTGCTGTCCTGCCTCGGCAGCGATGTCCTGGCGGGTCTCCTGCCGGCTAGTGGCGCAGGGGGTGGTGCTGGGGGATATCAGTACAACCGACCGGGCGGTGGTGGATTTGGTGGAGGATACGCAGGTGATACCGGTTTCGGGGGTGGCAGCCGCGGTGGCGACTTTGGCATCAGCAGCTACAGAGGAAGACCCGGCCAAGCTTACGGTCCACCCGGAAGTGGCGGCGACTCTTTTGGCAGACCGGGTGCAGCTGGATTTGGAGGACAATCGTCGTATAGACATCCGCAATTCGGTGAGAGTGGCAGTGGTGGATACCAAGACGGTGGTGCCGGAAGATACCAACAAGGAGGATATGGATATGGTGGACGCGACGGCGGAAGGGTACAATTATTTTTTATGTGTTTTTCATTCTTCAAATGGATAATCTAAAATAATAAGAAATTATATATATATTTTTTTTATTTATTTATAGGATATATTTAGGATATATAACAGAACATATAAAAAGAATGCTGCTCTTTCAAAAAATATTGTCATCAAATTTTATCTTGTATTATTATATATTAACGTGTCAGATTAATTGTATATATTTAAAATTTAGAAGAAAAGATATTTTGCAAAGTAGTGCAAACTCAAAAATGTTTTTATTTAACAAAGCTTGAAAATTTAAATGTTTATTTGCGCATAATATTTTTTATTATAGATTTATGAATTAAATATTATTTTTGTTTCTCACCACTTTTTCGTTTGTTATATAAACGATGATAGTTTATTAAGCATTATTTCGTAGCCGCAGCCGTACAGCTTCCAATACGAGGTCGTCGATCCGCCAAGTGGTAACGATTACTCTCATCGCCAGAGCAGCGACGGTAATGTCGTTCAAGGAGAGTACAGAGTCTTGTTGCCGGACTCGAGGACACAGATCGTTCGGTATATGGCTGATGACGCGAATGGATACAACGCAGAGGTTCAATACGAAGGACAGGCTCGTGGTGGATACGGAGGATATGGAGGAGGAGGACATCAAGGCGGCGGTTATCAAGGAGGTCAGTATATCCTTCGCACAAAATGCAATGATATGAGACAATGAATTCAAATATACGGGCACAAAATCACATTAATAATTGCGCATTTTTAAATCACAAAAGAAAAGACAATGCAATGTCAAACATAAAAAAGTTCAACATGTAAGATTGGAAATTAGATCATTTAACTAATTAATTAAAAATTATTGATACATATATCAAATAGCATAAAATTATGTAAATCACATATAAATTTGAAAAAAATTGAAGTAAAATTAATTAATTTAAAATTATTAACAATACACAAAATTAACTATAAATAATTAAATATTATAATTATAAATTCAAAAGCAGCTTTGTTTAGATGTCCACATTTCACATTGTAGAAATTAATAATTTTTTGACTAGAAGAGAAAAAATTTATTATAACTCTATATATATCATCATAGGCAGAGGCGGCGGTTTCGGCGGACACGGTGGTAGTTTTGGAGGCGGCTTCGGTAGCGACGGTGCCAGCAATCAATATTTGCCACCGCACAATTATCACAAaTAATTGTCGTCGACATGAAGCTACCTtACCAAAATACGGCATGTACCGCATGCATCTCCGGCGACAATCATCACGGACCTCCCTCGTTTACGGCTTTTATTCTAAATACAATAATCCTTCGCTCACACACATGAGACACGAACTCTCTCCCGATCACCTATGCATCCCTGTGCATCCACAAATCACTCTTTCACCCATATTTAACGACTACACAAGAACTAATTAAGGATAACTTGCATATGCATGCATGAGTGTATGTATTTATATATATGATATATATAATTTTGTACATGATAACTGTATTATCAAACATACGCTTGTATCTTCCGCTAAGCGATTATCAAACTCTTATGTACGTATTTATACGAGCTTGTAGTAAAACATGAATGTAAAGTACTCTTTCTACTTTATATTGTTTTCCCAATTTATCCTCAATCTATGCTTTAATCAAATCATTAGTCAAATAAAATTTTCGTTCGACATTTTATTTTGAACAATTGCCCGAAGAGTGTCAACATTTATAACGGTATTTTAACTACTCAGATTGTTATATACAGCACAGAACATTTAAGCAATATATCAGAAAATTTATTGCTGAAATATTGTTGAAAATATTGTTGCATCATTGCTGGAATAATCTGCGGAGCATACACAAACACAATATGTGTTGTGTGTATGAGTAATATTTTGTACAAAAAACACAATTTCTGTAAACACAATTTTGAATAATTTAAGATTACTTAACCAAAAAGTTGAATCTTTCTGAGATCATGCTCATTGAAAATTTTATTCAGTATCCTAAAAGCAATCACATATAAAAAATTTAGCCAATTTGATAGAAGCCATTTTTTCCATATAAAGCGTGCGGGCTCCTTTATAAATAAAATTATTTATCTACTTATTTATTAATTCATTTATTTATTAATACGAAAAATTAGAATAAATCGAGAGAATGTACAGTAAGCGCGAGGAGCTCCATTTCTGCATTCTTTGGCTGGGCGTCAATCTAATTAATCAATTTAATCGTTAATAAATCGGTTAATAATGTCAAAATTGAAAAAGAATTAGTTCAAAACTTTTAGTTTAAAATTCCATCTTTGTTCATTCCCTGAAATATTGATTTATTAAGAGTTATGGGACACCTTATATACTACATCAAAATGGCAGTTTTAATATCTTGTGATAAACATCTAATATTTTTTATAAGACGTTCGTAATGATTCTTCGCATAATATCCAATGCAAACAATTATTATAAAATATATTGAATAAAACCGTTTGTTCTATCTAATGACTGCCAAATTTAACAACACCGAAATTTTCAAACTGTCGAAATAGAGAGGTACTTTGTAATTCTTAAAATATTAAAaaTGTAAACATAACGCGAACTAATCAATTCTAGAGATCCTCAAATAAGAGATTAGACACCGTATCCTAAATATAGAGAAATGTGTAACTTAAAATGAGAAGCATTTATAAAATAAAATAGATCTATCTCACTGGGGTTGATTGAGAGCTCTAAATGTGGAGAGAATATATATACATGATTTTTAAAATGTTATACATGAAATCATAAAAACTTTGAATTTACAAACAGATACTCTTTCGATGATATTTATATCGCAAAATTAGAAAAATTATAAACTGGTTTCATTATTTGATCTTGAATCATTTCGGCGATGATACTTTCGTAATTTTACACTCTAACAATATTAACAATAACTAACAATATCAGTTCATACGTAGTTTTTCCGTACGGAGAATTATTATTAGACATTATTTAAAATTTTATTCAAATAATATACACTATATACTTATAATTTTTATTCTGCATCGTTACATAATGTGAAAGTGCAAGATTTAGCAGTATCCTGGTGAGTAATGAAGATCGTTTTAAACTTGACATTGCTCTTTAAAGTTACACTCATTCTTCTGGTATTTTAGAGTTTAATGCGTTTTTAATCCATCTGGCCTACTAACTTTAAAAAAaTAAATATTTTATTTAGATCTATTGATTGACCATAGACTATTACTCTCTCGCACTTCATGGAATACGATTTTTAATCAATTTAATTGAAAATGATTAAAATAAATCTAAACACGTTCAGCAGGAAATTAATTCTAATTGGTGCATCCGTTTTTAATTATGATATGTGTAAAATTACTCAATAAATTTGTTGGATTTTCGTAAATTGCTTGTACACTAAGTTCCACCTTGATACATTTTCCCCTTTTTACATTACTTTTCGTTATCTCATTCTAATATGTCTATCTCATGTTATCTTAAGCATTTTTAACATCATGGTGAATCAGTTAAGTTGTTTAAACGTGATATCCAATCTTACTGGAGGATCTCAAATTCCATTTAAGAAAAAGAAATAGAAATTTAGTGTACCATAGAGAATAAATCAAGAAACACAGTAGTAGTAGTAGTGGTAGTGATAGTGATAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGATAGTGGTAGTGGTAGTGGTAATGGTAGTGGTAGTGGTAATGGTAGCGGTAGTGATAGTGATAGTAGTAGTAGTAGTAGCTTCAAGTAAACGCTTCAAATAGGGCTTATTAAAAATAATTAAATCTAAATAATTAAACAAAGACACAATTAAAAGTCAAGAAGATTTTAAAGCATATAGGTATCATCTATTTTTATACATTTTTAATAGTTTCTGATTTAATTCTTTGTATACATAAAAAAAAACTTCCTAGTATTTATAACAAATAGCAATAATGACGAACCAATTTCAATAATTTCTGAAAAAAATTTAATGTAAAGACAATTTTGAAAATAATATTAAAATATCAAAATTAAAAATTAAAGAAGAAATTACAGTACAATATAACATTCTTGAATTACTGTAATTATTTAATATATTTAACATGTAACGTTTATATATTGTTCATTAACCCTAACTCCCCACACCTATTTTTGATTATCTTCCTCCTCACCTATGAGTTTATAGGACTCTGTAACTTTAAGGACCCTGTGCAACATTTCTGAACAAACAGCATATTTTTTAGCTCATAATATATAAAATCAATACCTGAAAGTCTGATAAAGATGCTAAACGAGATCTGAATCAAAAATATTTTATTCTCAAGTAATTAAAAAAAAaTTGCGTTGCACAAAATCGCAAAAACATGAGTACTCGCATAGGGTCCATTAGACCCATGTGTAAGGAGGATTAAACATAGTAAACATGTAAAATTTTTATTTACTTTTTCATAGTAATTTATAATTAATAAATTTGTATTTTATATTTAATAAACTTGAGTACTAAATCTAAATTGAAATTTAATGAAGCTTTCCTATTTATTTTAATACATAATATTCATTAAAAAaTATTTTTAAAAGTATCAAAAAAATAAATCAACAGTGTTTTACAAAAATCTATTTTTATAAAATTGATCTAATTTTTAATAATAAAATTGTGTCGCAATAATTATATTGTAACAAAATTTTCTTTTAATATAAACTCGTTATCAATGAAGGCATTGTTATTTTCCACAGACCACGTTATAATAGATAAAATAATAGAATTCTAAATAGAACAATATATAAAAaGACTTATTACATATAAATTGTTATAAAACAACATCGTTGTTTGAATATCATCAGAACAGTACTTCAAACAACAAAAAAATGTATCATATCATCAGTTTTCCTTACAGATAAATGTAAATTTAAACAAATTATTGAAAAAATTCTCTTATTTCAAAATAAATGTTTAACATATAAATGAGAATTTTTACTTAAGTACTATTGTTAAATGAATGTAAAATTTCTTTGGCATTATGATTGTAAAATAAATTGCTATATTATAAAGAATCTTTTCAATGTAAAAATATATTATTAATCACCTTCATCAAATATCGTTGTCAGAAGTTATATTAGATCTGTTATGCATTCCTCCAAAATCTGACTCACGTGTGTCCTTGACCTATATATAGAAAAATTTAAATAAAATTTCCGTAAACATTTGTGTATAGTTCAATAACTGAAAATTACCTTTGCCTAAAGGCGCTTTTTTTATTGTATTTATTCGAGATCTGATAGATACGCCTCTTCCACCTACATATGCAGACATTTTCCAATTAGTTGCAAGTAATTAATGTAATTAAAAAATTATAATCAATTATTATATTGGATATGTATAATGATACAGTTACATCATATTAACTTACCAATAGGAGGAAAGCTTTCATCATCTGATAGCAAAAAGTCTTTTGCACATCCAAGAAAAGGCGGTTCTAAAAACAATAAACAATATAACGTAAAATATAATAGATATAAATATAAATATGTTATGTGTGCAATAGAATTATTTTATTAATGAAAAATAGATAAATTATATAAAATATTCCATCGTCTATAATTTAAATAGATAATTTTCTAAACTTACGTTCAATATTTGGAGGTCTCATTGGTTTTTCATTCAACTAAAaaAAAAAaaGTAAaTTTAGTATGTACAATATTTTTAAATCAATGTAATGTAAAAAATATATAAGAGAACATACATAGTTTGGTACATTTTTAGTATTTTCTTCAATAGTTGTTTTAACAGATTTATCAACAGAATTTTTAGGTTTATCAACACTGGTAGATTCTTGTACTTTACTGTAATCAATAATTTGTACTGGTTTCGATTCTTTTCGGCGGCGCATTTCGTCTTCATATGTTCTACCAGAAACTTTTATTCTATGTTGCTCACTCACCTATTACGAGATAATTAATAGAAATCATCATTGATGAAAATATTGCATAAAATTTATAAAACTAATTAAACATATATAATGTACCTGTTCATGCATAAATCACTATACTAGCATATTTTTAATATATTATACTCACGCCTGTCATAGATAAAATTGCACTGGACTCAGGTGTAGATTTGGAAGCAGAATCCTTAACTTTTAGGTTACTCAGCAAATTTGTCACGACAGAAAAGTTCTCTTGTTCAGGCTTTGTAAGAGGTTTATGTACCCCTGACTTCATTTCGATCCCAAGTGGTTCACAAAACTCATCACATAATGTCCATGCCCATTGGTACAACACAGATTTACTGCACCATTCACTTCCTCCATCAATATATTTATGAAGCTAAATATTACAAAAAAAAAaTAATATTATGAATATAATTCAATTTATTATGAATATAATACACAATGTTATAAAATAATAAAATTTCCTACATGACATTCAAATCCTTTATCAAAGATATACGTATAGCGTGTAAACACGTTTTCAGCATAAACAGGAATAAACCGCATATCTCGATCTGTCCTTTTTCTGTAGTTTTCATTTGCCAAATGATTAAACAATGACTCCATTTCGTAAATTATAAATTGGTTCTCTTCGTCTGAAACAGAAACAAATTTATTTAAATACATATTAGCATATAGCATTTACAATGTATTTAAGTTTCTATTTGGCTATAGAAGAGAAAAATAATTTTCAAATATTCCTTGTATATTTTTTAAATTATACATACTTTTTACTTTACTTTTTAATATAATTGCCATCTAAGTTGAGATATTTTATCATATTATTTTTATTCTTTAATATAACGAGATATTTAATGGAATTCAACAGAAATTCAATAAAAATCATAAAGTGAAGAAAAATATTAAAAAATGAGTTAAACTATTAACAGCAGAATTTTCTTTAAATAAGATATATAAACAAAAAACATTATACCATAAGTATCTCAATTTAAACAATATTATGTTGCAATAAAAAAGAAATTTAAGAAATATATATACATATATCTATAACTATATATAAAAGTAAATATCTTAAAAACCCATTTTTAAACTTGTAACAGATAAAAAAGAAAGTAAGATATAATTGTATTTGCTTGTCTTGCATTTAAACATGGAATTGTTAAAATATTTAAAAAATGTGATAAAACTGTACTTACTTGCTGCTTTACATAGTCTTGATATCAAAGATTGCACTGGATCGTAGAATTTTTTTGTTGTATAAAAATAAGGATATTTATCCCCAAGTTTTCTACATTCTAGAAATTTGACCAAATCGTCATACATATTAGCAAAATTAGTCTCTCCACCTGGATATTCTACTGGGATATTATGAGAATTTTGACTTTCCTCCATTGCCTCCCGTCTATATCCCAAAGGAATTGGGGCACTAACAATTGCATGATGTACATCCTCTATACCCTTCTCAAGTGAGAAGATTCCAAATGCATATTCAGCCGGGAAATAATCAGAACAGTTGTTAACAATCATGTGGAAAAAATGGTTAACATGTACAAAGCAAAATTTTGATTGTGACAAAACTGCAATAACAAAAGTATTATTTGTACATTTTAATCTAGTAACTTAACATATTGTATTTATTAAAATTAGTATATTGTACTTGAATCTCATTGCTTCATATTTGCAAAATTTTGGACCCAAAAaGAAAAAaTTATTTCCTCTTGTTAAATTTTGTGTACAGATCATGATACCATTTAATATACTTGTTATTCTTTGTGACTTCATCTTTTTAAAACAAAGTCACAATTTTCAAAATGTAAAAAGCATTAAATATGCAGTAAGATACTTTCAAATTAATTTATATAATAAATTATATTTTATTATGCTACTTACTATTAAGATTTGCAGCTGAATCAACTATGTGTTTTATATTTTCCTGCATCTTCATCTTAAACAACTCTGCTTCTTTTTGCTTCTGTTCCAGCATAGATATTGACTCTCCGTATGATGTTTTCTTATCTTGGTTTGATATTTGTGACTTAATTTTATCTTGTTTGGCCATTTCTTCGTATGGGGCTTTTTCAGGTTTACTTAAATTCTGATAAAAAAAAaaGAAAaTATTTTATTACAAAATTAAAGAATAGAATGTATACTAAGGTATAAAATAAAATATTTTTTATTATATATTTACTTTGTCATAATATATAACATTTGAATTATTTTTATACATGGAATAAACAAACTTTTTCATATCAAATTCTTTGAGAACACATTCTAAACACTTATCAATAATTATAGTCGTTAATATCTTATAATTTCTTATAAAAAGCACTTATCAATAATTATAGCCACTAATATTTTATAACTTCTTATAAAAAAAAAGAAAAAAAGCATAGGTCCTAAGAATATAGAATTCACTGTTAAAAAATACAACATATGTATGTATACATATTTTTATAAATATTATTAAAATCAATCATCTTTTCTTATTTTAACAGATATAAAATCTTAAAATTAACATGTCATTTATTGTTGAGAAAAAGATAGTGAATTATACTTGCTAATTTATATGCTTAAACAAAAAAAAaTATTCTCAATGTCTTAGTAATTTCTTAGGGCATTTAATTCTAACCTATTTTTTTCTGATTTATTATGCTCTCGTATATTAACTGTACGTTCAGACGAAGGACAAACTCTTGAAACTAAGTCACTTCCTTTCTTTCTCTCCAATATCTAATTTACCATCAAATGTGTTTTTAGCTCTCAATTCAACTTTGTTGGTATTTAATTAGCATTTAATTCTTCAATGCGTTAGTATTTATTTAGCGCTGAAAGCTAAACTTAAAGACAATATCAAAAATTGAAAATGCTAGAATCGCACATGTGAATTTGATTCTTTTGTAAAGACATTACCCGCCATTCGTCGTTACAATCTGGATCCTGTTGAACGTCTTTGAATCCATTAGGAAACTTGCGCCCTTTCGCCTCCTCGCGTTTCTTCCAAGAGGCCATGAAAAAAAaGAATGCATTTCTGCCTTTGGCCTTCGGCATTTTGCTCCAGCAAGAATAAGATCACTTTCAGTTGCAAATGATCTGAACGTCAACAATCGTCAGCAATCAATCAGCAATGGAGCAATGCAGCAAAGTAGCAAAAACAAGTTAAGACTCGAGGCAAGTCAGGGCTAGAGAACCTTTAGGAGTGAGAGGCTTCTTCTTTCTTTGCTTGTACTTTGGTTTATTGGTTTCTCGCTTTCTTCGAAAACAAAGTACTGCGTAATTAGATGAGTGAGAGGCTACGAAAGGCTCCGATCCACTTGATGCTACAAAGCGAAAGTGAGCGAAAGCTTTTATACAATCAAATGGACCTCATCATGGCCCGCAGCCTGTAACGCTTGAAACTCGAAACACCCTCGCACACTAACGACCTCGTTTATTTTCGTTCGGAATGTGAACTACAAGTCACATACATCTTGCGACCGTATCGTTAAAATCGTATCTCGTAAAATAGATGTGGTTCGTATCCGTGGTAAAAATAAATAGTAGATGCAACCAGGTGCAGCTTTTTTTGATTCATACATTTAAATTTGACAAGAACTAAGAACAAGGAGAATATTAACAAAACCATATTAAAGAATTTTATAAATTACTTTCTTTCCTAAACACAGCCATTGTTTTGTAAATTTAAAGAGATTCTAACTAATAAAATAAAGATGAAAATTAAGAATAACAAAAATGCAATTAAGTCTTGACTTTTAATTATAAATGTTTGAATATTTATATAAAATGTGATAAAAGCATAAAAATATTTAAACATAATAAAAAaCAAAGCATCCACTGAAATTTTTTTATTCTTTTATGATCATAAATATTTGAATAATCATGTAAAAAGTGCCTATAGTATGTGAATACTTAAACATTCACAATTAAAAAATTTAAACAAAAATTTAATGGTAATTTTGTTATTTTTAATTTTCTTTTTACTTTCAATATGTATAAAACGTTTGAGACGTGTCAGAAACAATATTAATTCTATATATTTTtATTCAAAAATTTGAATATTTAAAATTATTGTGTATCATAGAATAGATAACAAAATAATTTTTTTTCATGAAGAATTAACAGTCTACAAGCATAATAAAAAATGGATAAACATCAATACTTTTATGCAAACTGTATTTCGAGGCAAAAATCTACAAAATATATTCGAAAAATAATTTTCTGGAAATATTATTAGAAAATAAGTTCATATGAATACATATTTCTTATGTATATTTTAAGCGTATATATTTCTAACTAGAAGAACTTGTGATACTTATTAAAAACTATTTAAAACCAATAAGCATTGCTGGTACAATGTCGGCTTTACTCAACATCTGTTTCTTCTCTGTTCGCCCCGGTAACATTAGAAGCGCATTAGCACCTTTGCAACTGAGTAATTTACTACTGATTTGATTTCCCGTGCTGTAAGCCAATGGAAGCATTTCTTTGTTATTCCACTTCAAGATCACTCTTGCATATTCGGGACGTGAATCCAAATTGTATGACGACGTTAACTGTAATGTTAAAACAACATTTTACACTTATCGTGCCGCATTACCGTTTCACAAATTGTAATGATGATATGAGACAAACCGCAGCTTGCACTATAACCGGCTCCGATGAGTCGTTGCGCATCTCGTTCAAAAGCGGTAAGAGAAACAAATGTGCAGTAACGGTGGCTGACACCGGATTTCCCGGCAAACAAAGGAAATATTTCTTTTTATCTAAATACGTGCACGTTGCAAATGTTGTTGGTTTTCCCGGTTTCATATTTACACGCCCTTTGAGAGAATACATTTAATATTTCGTACAAGAAACATATATTTAAATACATTAaTTTAAACATGATTAAAAAAaGGGTACCAAAGTGTATTGTAGCTTTGAAATATGTCTCTAAAATTGGCTTCAACAAATCTTTGTCACCCATTGACACGGAGCCTGTTGTCACAAGTACATCTACTTTTTCtAGAGCCTCCTTAATTTTGTTTATCATCTGATCAACAcTATAATATTATATATTATATTAATAATAAATTTAATATTGATTCTTTATCACTATATTAATAAATCACTTCATTAACCTTCGAGTGTTTATATATAATATTTGGTAAATTTTTATCGAAGTACTAATTCAAGTTTAGTAGTTTTCGTTACTAAAATTTTGGTACCTTAAACATTTAATACGCTTACATTAAAATAATATTAGCTTAGTTATTCTAACATCTAGcTACCTGTAAAATAGAAAAAaGTAATAGAAAATTCTTAATTTTGTAAGTGAATTTTCTAGATTAATATTAAGAAAAGTATGAGTAATACTCTAAGGTTAATAAATATAATAAAAAAATATAATACAATGTGCTGAGAATAAATTTTGACATACTTGTCAACTGCAATTCCGAAATCCAAAGAATCAAAGCCATTCTCTTTTAATAGTGAAATGAGAGTTATTTTGTTGCTGTCGTAGACCTTTCCTGGTTTCAAAGGCTCTCCAGCTTCCTGTAATTCGTCTCCTGTTGACAATATACCTATATCTGGATGTTTAGTAACTGTAACATGCTTCCTGCCGCAAGCCATCAGAAGTCCCATTTCCGCTGAACCAATACACGTGTTTGAATTTAATACTAAGCTTCCTTTTTTTATATCGGAACCAATAGGTCTTCAATAACAAACAATAATAAACACAAATAATAAATAAATTTCTACCAAAAATAAAATAAACCTTTTTTAAGAATGACAAAGCTTATTGAGCCTTGTACCTGATATCTTGTCCTTCTTGAGGTACAGTCATTATCTCAATTTCCATTTCTTCCATGTTGTCAACGCTTTTTGATATTAACTTTGTGTCCTCAACTTGTACAACCGCTGTTGCTTCTACAATCAGGCAAAAAAAGATGTAAATCGTTTATCGTGAGTAAATCAATATAAATTTAATTACAATTGTTTACCATCGGGAACAGGCGCTCCAGTGTTCACGCGTACGCAAGTGCCACATTCAATAGACACTAGAAGAAGAGGCTAAAAAAGTGTATTAATCAATAGTCTTATTCGAATCTTACTGGATCTTCGTGCCAATATTTCTTGTGTGATTTTACATACATTTTCATACTTTATAATATTTGGGAAAGGGATAAGTGCTTATTATCATCATTATTATTATTAAAGTGAGTATCAATTTAATATTGTGACGTTTACTATTCTTATTTCAACTTAAATCTGTGTTATAAAACTGAAAATTAATTTGGGGCATAGTTTGACAAAGTTGTGTATATAATGTATATAAAGTTACTCAAGAAATATTTAGCACAAAGATCCAGTTATGATCAATAAGGCTATTATTTCATTAAACGTATTTTCACATATTGGTCTATATTACTTCTATTATTATTTTCATTTACTATCTTCTATGTATGGCATTAAATATTTGTTATTATGACTTACAGCGGTCCCTGCTTGCACACTACTCAACACCTTTCTTCTGCCCTTTCCATCGCTCGCTAACACTGCATATCCGTCTTTTATGGAAGCTCTGAATGGTGGAAGATCGCAATTGGAATATACATCCTCAGATAATATTCTACCGTAAGCATCTTTCACATTCACAGTCTCTACAATTCTTTTTtCATCTACACTCATACATATTATTCTCACTGCTTCTTCCACAGAAATCATAGGAAATGGAGATTCTCTAAGGCGTGTTGTCACATTCTCGAAGTTCGTCTGAAACTATCTAATTTTACTACACAATTTCATGTAAAATTATTTtGTTTTCAAAATAAAATAAAATATCTCACTGGAATTCTACAAGAAGTATTGTGCGAACAAGATGTAACATTATGTTGCACAACATTATGCGTATCTTTAACTTTTGCTTTATTGTCCAAGATCAAATCTACGGCATGCGGAATGGCAGGCGCGATTGCAGTAAAGCATTCTATTGCAGCCTTATGTGAACCTGGTAAATTAATAATTAGGGTCCTTTTTCGTATTCCACATACAGCTCTGAAAATATTATAAGTTGTAGCTTTAAAGAGATTTCAGTGTAAATATAGTGACTTAGTGACTTTACCGAGAAAGCATTGCCAAGGGGGTGATTTTTAGACTCGCCTCGAGCATCGCTACAGACAATCCAGGAGCTTCTTTATCGATAACTTTCCTGGTTGCCTCGGGAGTAACATCTCTCCTGGAAAATCCTGTGCCACCAGTGGTAAGAATGACATCAGTTTTTCTTTGATCACTCCAGTGGATTAAATATTCCTACAAGTCAAGGCAGTACAAATATGTAATAACAAAATCAAAATATTAAAAAAAATTGTTAAAATTTCAACTACATTATAGCTACCATTATTGACGCTTCGTTATCTTCCACAATAGCCATGTAAGAAaCATCTCCTATTATTTTTTCTGCACTGCTGATAAACATTTTTAATCCAGGTCCACTTTCATCTATTTTCTCACCACTGGCACAACTGTCACTTACTAAAAAAATATAATGGAATCATTAGAGAAAAAACCAACAACAGTCACAGCAGGATGTTTGACAAACTAGAAAAAAATATATTAAATTATTTAAGAAATATTATTGAGCATTAAGATTATGCTATGACTGTTGTTATCCTTTTCTCGATTCTAATTATGTTGTACATGTCACATGAGTTTGTCATAATTATTTGTAGAATCATTACAATACAAAAAATGTGCAATATGTAACAAATTTATATATTAAACATAAATGAAAGCTTCTTATAAATAAAAGCAAATTATTAAGACTTATATAAAATTAATTAAAAaTTATTAATTAAAGATAGAAATACAATGTAACTGTATTTAACATTTAATGCACACCTTTATTTTTCAATTCCTTACAGCATGCCATGAATCATTCATGTTTGTTATTAATTTTCATTACTTTTACAAGTACaTAAAAaTTAAGTGACTCTTACATGTACTTTAACATCTCTAGAAAGTATTTGTGTAATTATTAaTTAAAAAAATTATATATAAATGTTATTGCTAATTATAACTGACAAGACATTTCGAGAAAAAAAAaTGCAGACTACAAATGTCCTAAGGCGAACATTAAGTATTAAATTAGTCTCCATACGCATACATAACTAAAATATCTTATAAACTTTCATTAATTTTTATCAATATATATATAAGAAAGCTTTTAAAAATGATTCCATGTAATATATTACCAGTTAAAATTGCAAATCTTATTGGTGTCATTTTGATCTTCTGCAATAGACTTTTGTCTAAATAGCTTGTGACTAAACAATTTTTtATCAAATCTGTGATTACGTGAAATATGTACTCTCCATTTAACTGTACAATACTGGAAAGAGTACTAGCAGAAGTAGCAGGTAACAGCCACTTGTAGCCAGCTGAGACCGGTATTCATAATCAATTTTTAAGTTAAATGTAACATCATAAACCAATCACAGAGCCGTATTAAGACATTACTTATGACGATTTGAAATAAGATCAGATTATGAATATACCAGGCTTGAGAGAAGTTTTGTATAATATTAATATTAGTTCTGTTCTTTGTAACTGCACTGTGCTGCTTTCTGCACTCAAAATGAAATAGATATATAAGACTAGACATTGGGAAGAAAAAGAGGAAAGATCAACGATACAGTAAGTTCAATAAAATATCTTTTCCAGTACAGTATTAGGCAAAAGTCGATTTGGATTCTTGGATAGATCGCTCATCATTCGTAATATTACACTACTAAAAAaTATCTGGAAAACGtACATACCTGGCAGGGCTATAACAAAGACAATGGAAGCATTtGTCTTCATTATACGTCAGCACAAATACTGATTAAAAACAATACATTATACTCATTAAAATTAAAAGTTTCACAAaGATTATAATTTATAATTATTtATACAATATTTtATTtAATTtAAAaTtAATTATATAGTATTTTATTTGGTGTTCAAaCCGATGTTTATTtATTTTtACTtNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATATATATATCATTaCCAATTaTAACTGAATATATGTCACACAAAAATTTATTTATtCAAtCGAATACACGAGCGAATAAAAGAAAAGATAATAATAAGGCAGCCAATTTGATATAGATTGGTTCCAGCGATAATTCTCTCAAAATAAAATAACGATTAAAAATTTTTAAGTCCTCTGTGGTTTTAACAATACATGTACATTAAAATTCTGCTCCTCAaTGAATTAAAAATAAAAAAAAATAAATGTAGACTATCAGCACATTAATATTGTTGTGTAATATAATAAAAATGAGACGCGCTTGTAGAGGTTCTTCGTTCAGAAGGAAGACATATAGACATTATACTTATATAGACATGGTACTTATATAAGTATGTTTTGTCTTTATTCTCTGTGCGTTAAGTGACTAAGAAAGCGTTATGGTTCTTACTGACTTTGTGTCCGCCACCAGAATTTGTACTTAACCCTGCTTTTGGCTTGTTCCTGAAATATATTTAGAAAAAATTAAGTCTATGCGTAATAATTTATAATTATGCGTATAAAATTAAGATTGTACTTATAAAATGCTTACACGTTTGCATTTATAGGTGTCTTCGATGCTGCTGGACTGGATTTTTCTTCGTTATCGGACAGCTCTAGTTCAAGACTTGATGATTTTCCACGTCGGCCGTAATACCTACACGTAAAAAAAaTTATACAGCTTACATTATAATATGTAATCTTTGAAAGTTAATTCCTGAAGAAATCTTTACCTGGGCAGTGCTGGTGTTTTATTATCATCGCTTCTTGAACGTTTACAACTAGATTGACTTCTCGATCTCGACCGAGATCTTGATGGAGACTTCGATCTTGAACGAGACTTGGATCTCGACTTTGACAGCGAATAACGTCTTTTCCGATAACTATCTCTGGAATGGCTCCTATTACGCGATTTAGATCTCGATCTTGATTTCGATGCGCTCGAAGACGAACTCCTTGACCTCTTCAAACGTGAACGTGATCTAGATCTTGTCTTCGATCGAGAAACTGAACGCGATCGAGATCTGCTGATACTTCTACAGCGCGATCGTGATTTACTTCGCGTTCGCGATCGTCTGGAACGACTTCTTGTACGGGACCTTGTGTATTTTCGAGGTCTTGAGCGCGTTCTTCTAGATCTAAGATATATTAAATATATTAAAATAAAACATTAACTATGTCTATTACGTTCTTTTTCTTGCAACTCACCTCATCCTAGATCCACTTCGTTTCCTATCGCGTGTTCTATATGATTTAGTCCTACTAACAGAACGTGAACAACTTCTTGACCTGGACTTGGATATTTTCTTACTGATACTTCTATCATTGAAAGGAGGACTATCTGATCTCCGCCGTCTGAGATACGAATAATTGACTTTTCTTGAATTCGACGAAGATACATGTGATGTGCTACCGTGAGTCTCTTCTTCTCCACCGAAGCTTGTAATGTAAGTAATCTGTCCCGTATTTACAGGTGATGTGGATCGCGATCGCGATTTGGAAGAGGATTTTCTATAAGGATTATACTCTGGGCTTTCTCTAGCTGCATAACTAAAATAAAAAaGAATTTATATAAGCAAATACGTAAAAAAaTGTATTTATTTGTAGAAATGTAATGAATTATTACCTAGGTGGACTCATAACGCGACCTATCATCTTCTTTTCTCTGAATGCACGCCTTTCTCTGCGCGACCGTCGACCCTATTACATATTAAAATGAAAAATGCATTAAAATGTGGCATATTTTCAAACATTTAGTTATAATATACAATATTATTATAATATATAATACAATATTATATATACCATATTATAATTTGTAATATATATTGTACACAAGTAAAATTATAAAGATATCTTTTTTTtAATTTAATTATTTACCGAGTACATAGCTTTCTCTTCTTCTTGCTTACGAGCCTGTCGCAAGGTTTCAGCTTCTTCAAAATCTTGCGTTAAAAAACTAAAGTAATCAGCACCTAAAAGTCCATATTTTTGAGCTACTAAATTCATCTCATGTGCCTGAGATGGCTCTATTTGGGATACATCTACGCATATATCTAAAAAAAaCATTATATCATGTTAAAAATTATTAATATATCATGTAGCATTTCAAAATATATAGTACTAACACATTATTGACTGACAATGAGACATATTAGCTCGGTTTTTATTGCTCAAACGTTATTGGCCAATGACGAGTTTATATACAGTGCAAAGTTATTGGGACTCAAAATTGATAGTTTTCATTATAGGATTTGTGATTGTTTATTCTCTTTTTTGACCTCTCGTACATTCTAAACAAAATTTTGAAGTTATTCATATTTGAATAAATAAAACAATCTCAAGATCAATGAATGCATATGCAAAAATAAAAACAATAAAGTCAAAGACGAGTCAGTTAGAATAAAAAaTTATAATATATAATCTCAATTTTATATTTGTAAGAATAAATTTATATCAACATTTACAGACATTTCAGACTCACTCATCTTTCATCAGCATGAAACAACAGTAATATTTCTATCCTGACAAATGAACAAAATTAGACAAATAAATTATTGATATTTACTCATATCCTGTTTCAATATTGATTTAGGAGTATAATAGCCAATTAGGCGTTAGTTTCTGCATAAAATGCCCAGTCAATAATGTATTAAATATTGCAATAAGCAAAATAATGGTACCTAAATCTATATCGCTATCTTCATCATCTCCCTTTTCCTCCGATATAACTGGATCCACAGTTTTTACTGGTTCGGGTATCGGTTCCTCGGTTTCATAATTGTATCCAATGGCAGCGTTATTAGCAGATTTTTTCTTATCCTTTGCAGCATCCAATTTTGTCGACGAACCAAACTGTTCTTCCAAATGTATTTGATGAAGAAATTTCTCTTCAGTCACTGTGAAAGAGACATTCCATCAAAAATACAAGAAACTGGTAAAAGATTCCTGTAGTGAGAGGACAAGCGACATACCGCCTAGAAATTCATTTTGCACAATTATACGATAGCGCTCGTAGTTGATGTGTCTGTCTTCGCTCGTTAGAGCAATATCAACATCAATTGTATCCACAGGCTCTGGTATCCAGTCCAGATGTGCTCGTACATCAAAACGATCTATGAGATTGTCTTCATTGCCCTGCCATGGCATCCTGTCAATGATATATTTTTCTTTATTGATGAACAAGAACAATTAACTATTGTATTAGTGATCGTATCTACATCATAACACTCACATATTTGCAGGACTGTCACCCGCGGCAGCTATCGCTGGATCCAAATGTATCTTGCATGGTCTACCGTGCAGTTGGAGAAATTGAGTAGGATCCGATTTCTAAATAAAGCAGAAGAACGTTCAATTGTTATACATCTAGGCAATACTGCTCACGATTATATCTTATGTAAGAAAAATGTAAAAAAAAATGTAAAAAAAATGTAAAAAAATGTAAAAAAAAAaGACAGAGAAAAGGCGTAATAATGAAGGTTAAGCCAAGGAGCAGAGAGAAAGATACGTAAAAAATAATGCGCGACGTATCGATCCATTCCAAATTACACGAAGAAAGAAAATCCGTCGCGTATAGGTTTCTTACGATTTTCTCGTAGTAGTCCCGTCTACGTTCCGCTCTGCGACGATAATCGACCAGCATACCGCGGATCTTCTTCTCCTGCTTGCGTGCCTCGTGCCACATTCTGCCGCCGGTCTTCTTTACGGAGAAACTCATTTTtCCTTGCTCACTACTGTGGATCAATTTCGCGCGGCTAGCTTGACGTGGGTGCCATTCGTCCAGCTGTAATCGCTAAAAAATTGAAGCACTAATAATTGACACGCTTTCCTCTCTCGCGAGACGGACATGTTGCGGTTGCCTCGCTGAGAGCTACATCAGCGACTTCTTTCGGAGCGCGCGGAAATCACTTTATTGCACAATCAGCCAGCTTGCGGCAGTTGCGGCGATCAATAATTTGAATTAATAAATTATCCAATTTCATTTTTCAATACACTATTTAACtAAGTTATATTAAATAACTGAAATTATTtATTCAAATATTTATTATtAaTAattaTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGTGTCACAGACTTCAATGTATTATTATTAAATAACTATAAATTTCCTAAAGATAAATAATTATTAATAATAAATATTAGAATAAaTAATTTCAGTTATTTAATTTAACTTaGTTAAATATATTGAATATATTGAAGTCTATGGTGTGCGTACACGCGTGTGCACGCGTGACATGCGTGTATATGTGCATATACACATTATTGAAACAGCACATTAATTGACAGTAATAATTGTAATTTCATCGATTAAAACGTTaCACTTTATAAATTTAATTAGCAATATTTATAGACAATGAAATCGATATACGAATGGCGAATGCAAGATGAAACGCGAGAATTATGCAATCTTATAATGAAATCTCTTTCTCTTTACTTCTCACAGCATTGAACTCGCTCGAAAACCCCGTATCTGTGCCGCTTAATTTTAACGTTCGTATTTTATAGAATATGCTCGTTTTACACGCCACTTTGTGCATTTTCTCGTCTCAATAATCTGTTCGTCCAGCTAGAAGAAGGATCAAAaCGTTTAAAATGGACTTGGAGACATTTATATCGCGAACGCGTTTTATTCTTTTCACGACGCCTCGGTTCTCGCGCAAAGGGTGCGGATCGGGTGCGGCGCGAAAGGTCAGAGCGGAAGAAAAGGTAACAGCAGAAGGTGAAGATGTTTTTGTTTATTATTAACCTTATGTAATATCGTTTCAAATTTTCAATTACATTATTATATATAATAATAATTATAATAATCATCATAATAATGTTATGACAATGTATACACGTTAGATACAAGTTCATTTTTCTTCATGGAGTTTTGTTAATTATTTTTTTTTttCCATCTTAATAAATCGGTTTTTTGTTTCTTAATTCACATTTTTCCGCTTCCTTTCTCTCACTTGCACGCATACATCCGCAGGCACACGCGTTTTTTCTCTCCTTTTCGCTCCTCGTCTCATTCATTCCTTATATTTTTTTTTtGTCCCGATTGGTGCATGCCGAACGAGACATCGAGATATTATCACCCTTTCATGCTCGATTCTTAAAGAACGCTTATGCGTTGCCTCTCAGGCGCATCTCTCATCTTTCTTTCTCTCTCTCTCTCTCTGTCAGTCGTATTATAGTAATATTTGTTTCTGAACACAATGCTTTTACtCATGACGTTAGGAAACTTAGGTTACTTTACTTCCCCGCCGCATCAACATGTTCCAAAGATCTGGTGATCAAGTTTCCCCGCGAGCGCGCCTTGCGGGCAAACTTTTTCAAAGGTCGCAGCACGTGCGACTCGCGCTAGGTTTACAAACTGAAACGCAGAGATGGGAAATAACGCGTTACAAGCAACGAGTCGCTGATACTTTCAATTTTTTTTTtATAATAATAATTTGGTAAAGACGTTACAATTTTTTATAATAGTAATAGTAATCTCAGGCGGGAACAGTCACTTTGGACAAGTAACTTTTTACTATTACGTGTTACTTGTTGAAAAGTAACTCGTTAGTTGACTCGTATCGAGTTAAGTTACGATTTATTAACTGTAAGAAAAATTGTATCGTCATTCAAATCATTATATTGGATGTTACGCAAGTTCTTTTGGTTCTTTTGCCTTTTTTTCAaTAAAACATACATTCTAATGTATGTTTCATTAAAATATGTGTGCTTCATATTTCAATAAAACATACATTAAAAATATATATTTCATTGAAATAGGGTAGGCCGAACAAACTAATGTAACAACTCTGTATTATAAAAATGTAACGGTATCAGCGTTACTTGTAATTTGTTACTTCCCATCCTTGCCAAAACGTAAAGAAAAAGCGCGAGCGAAGCACATGGAAGAAAGATTTTCCACGACACCGATTGACAATTTAACAAATTACATGCGCGAACAAAAATTCATAAATACGTCAATCCTTCATTGCCCAAATTATTCGTTGAGATTTTAAGGAGATTTCAATATATACAGATATTAGTGTTTCAATGACGGACCTATATCTTCTTTTTACTGAAGAACAGGAAAaCAAATAGATGCTTATGGTACAAAACTTGAGAATTACGATAATCGTGTCGCTCGAAGAGCACGAAAGGTAAAAAGTGAACAGTAAAATAAATCGACAGGTGATTTTAATATTACGCTGGGCAACAAATGATCAAGAAAGCTCGTCGGAAAATCGCTTTCGCGCTACAAATGTGTAAAAATATGCGAATAATGCGCAAATGTCGCATATACGTTAGCTAAGATAAATAATAATTAAAATATAAATCGGTTtCCGTTATCGTTTTtCTCATGATCTTtCTGTAAATGAAGTTCTCTtCATGTAAAAaTAAATAAATAAATATATATATaTATATATATATATATATATATATATATATATgctATGTgTGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACGCTCAGAATTTGTCACAGAAAATCCTGAACTTCCCGCCATTTAATCTCTCTACACCTAATAAATCATATCCTGTACAACTTCAACTGCGGAAATTATCAAAAAGGTCATTGAGGTAAGGTGCGACATATCCCGTTTTTACGTTTCCTCTTTTTTtAGATGATTTTTTTCGGAGAACTGTTCTCTCTTCTCTCTTTAGGTATTTATTTATGTCATAGCGAATCTATCTATTTTAAGCATTGCTTTCGAGCTATCTAATCACAACACAGACTCATTACGACTCTTGAAATTTAATGTATCTTAAGCACCGATTGCCGTAAATCTCAATGCGATATAAAAACATTTATGGTACAAGTGTCAGTGGGCTTCGTATTCCTATTTGTCCGTTGGTTGATTTACATATTATTAGATATTGTTAGAAAATTTGTTTTCGTTCGGTAACTTATTATAAATTCGAGTATAACAAACTTCAACATCTGAGTTGCAATATAGAATCGTCTCGTGTATATCTCATTAAATCGTATCTGCAAATGTTCTTGTATTGCAGGTGTATAAAAATATACAAATCATTCGAAAGGCCGCACGAATAAAATGATTCTTAGCAGATCGAATGGCTTGTGAAACGTTAGACTTTTCTCAGCTACTCGAAAGTATCTTATATTTCTCATATATTTACAACTAATACAACAAGAATTCAAATCTAAATTTCACAGTGAGACTCGTTACTTTTCCAGAAAATACATTGTAAGAATTCTCTTGGTCGTCTAATACCTTTTTTTTtGGCCAAGCTCTTTTGACAACAGTCGCAGTCATGCAGACGAAATTGCTTTGCCGCTGCTTTATATTTACGCATTAAAATTTTCGTACAAAAAAGaTATCGCAATTAAAACGTTAAAGATGACGGTTATATTGAGAATTATACATGTAGCTTCATTTATCGGAGACCACATAAAAaGACAATTAAAATTAGATATTAGAACGTCTTAAAACAAATTAATAATAGTAAATCAGTAAAGATCCGTCAACAAAAAAAGATTATGCTTGTCCAATATATAATGTAATAAATGACATAATCCACAGATAAATTATTCTCTAAATCTTAAAGTCTCCATTCATGTAATCTCTTTTGTATGAAAGAGTATAAAAAGCCGCAAATATATCAAATATACCTTGTAAACAGACTTGGTATTTCCATATTTCGTTATCGTGATTATAGAAAAGCAACATGCATAATTCTTTAGATTTCTTTCTTTTTACAGCATATATTATTATTTTCTATTAAAAGTCATACTTTTtTtCCTTTGTAACATCTGGATGGTACAGGGATTATAGTTGCATTTTAATGGTCTGCCTTCAGGTACTATACTACACTTACAATTGGTAGTTTCATGATGACAAAAATGTGGTTGATGATAATAAGAAAGAAATTATTAGCTTCTATTTTTGTTCGTCATCTAGTCTTATAATACATAAATAATAAAAAGATCGCATTTTAAAGATTTAAAATATTTTGGCCAAATGAAAGTAGAATCCTCTATAGAAATAAAGAGCCTACATTACAATTGGTGCGAATGGCATAAGCGCAGCGACCATCGGGGCAAAACGGCAAAAATCAATGACGATTAGCGTTGGAAACACGTGTGTATGCGAGTACGCGCGTATTGTTTATTATAAAGTATCTAGGTTCTTTGTATGATTATATCATTCTCGATTTTACGTGTATGCTGCTTTTTTAACTTTCTTATTACTGCGTTTTTTTATGTATAAATATGTATTGTTGTTAAGCCGCGCAAACCTCGTTTGTTTAGAGTCCTTGTTCAACAACAAACTGACGTTTGCAACATCCTTGTCTTCCATTAAAGTAAATAAAAGATTTAAGTTTTACAATATCTGTGTTTGTATGTGTGTGTTTTACCTCCTCACACTTAAAAGCTAAACCCTAAAGCTGCACTCTTATCATTCACCTAAGTGTATTGTACAAATAACTAGCAGTCGACGCGACTGTTTGCTCGCAAGTACTTGCTAAACCGTTTACATTCGTGTGACATCGTGTATAAAACTCTATTGGAGTACATGCTTACATTGGTAATTCTTACTTCCTCTTtCTTTTTTTtACGCGGTAATAATAGTAATTATCACTTTTTAGCTCTCTAGGCCACACAGTTTGGTTGCCGAAAGTTTTCCGCTCAGCCGTTTCTGCTAAAAAACCTGCTAAGAGTGTCTGTGGAAATCGGGCAGGACCCGAGAGGCCAGCTGGGTTCATCCTCACTAGACCATTACTGTCTGTCCATGCTCGAAGCTTTCGTCAACATCTTCCGTGTTAGACACATATAGCCACTCTCAACATAGGGCCAGTCAGCTTGATAAAAAaTACGAAAAATTCAGCAACGCAACAGAAATTAGAGGTTCCCCcTCTTTTTTCTCCCATCGCTTTCTCCTCTACTCTTAAGATTTCTCATACAGTCGTTAACGCCGCCAAGCTTAGGGTACTTTTTCGTTTCTATGATCTCTTGATACACAGAGAGTTTTGGGCTTTGTGATTTACGATTATTTCTTTGGATTTTCCGGGAAATTTTATTTGCATTTTTCAGAATTGTTCAGCCAAACCAACATGTCCGAAAAATTTCTTGAATTCACTGCCGAAGTTGAGACTAATCGCAAGACAACGTGTTTTATTTCTTATTTCTTTTTGACTCTGTGATGAGAAAGCAGCATCGGGGAACGACTTTCAAGATGTTCAACATGCCATTTATCCGTTCTTCTGTCGTTTTCTTCTCAATGCCACATTATATGTAGCATAACATCCATTCTCAAGGCATGCCATCTCTGTAAATCAGCTACTCATCTTTTTCACGGTCTTGCGTTCGCGACAAACTGTATTGTCCACCGTCAGTTGTCCCTTCTTGCCACTTAGTGGATAGCGACTGGGCTCTGTTGGACGCATACCCCGACCATCGGGCTATCTTCTCTCTCTGGATCTCGCTGGTTACCGGACGACACCGTTGATGGCTGTCTGACCATACTGTGGGTATCAGTAGCCGAGTAGCCGTAGTTGTAAAAGTTCTGCTGCTGAATCATCGGCGAGGTCATCAGGTGGGGTATACCAGGAAGAATTAGGCTATTGTACGATC 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a/2023/data/reference_assembly/gv_examples.fa b/2023/data/reference_assembly/gv_examples.fa new file mode 100644 index 00000000..b394a8b4 --- /dev/null +++ b/2023/data/reference_assembly/gv_examples.fa @@ -0,0 +1,4 @@ +>spQ7F1X5 rice +MADRAPPPPPPPAGIDSRSGFCAATRIFHSTRAPGDLPPESLPMTAAAYAFSLLSSSTLPGRPALVDAATGIAISYPSFLAAVRSLAGGLWCSLGLRPGDVALVVAPSRLEVPVLDFALMSIGAVVSPANPVSTPEEYAHQVALSRPVVAFAAPEVAAKLPEHVRCVVIGSDEYGRLAASDGRRAAAPAAVAVKQSDTAAVLYSSGTTGRVKAVAITHRNLIALMSLHADNREKVAREAAEAGEEPPPPAVTLLPIPLFHVFGFMMVLRSVSMGETSVLMERFDFIAALRAIERYRVTLLPAAPPVLVAMVKYEEARRRDLSSLLVIGIGGAPLGREVAEQFASVFPNVELVQGYGLTESSGAVAATVGPEESKAYGSVGKLGSHLQAKIVDPSTGYVGDDEATAATVDSEGWLKTGDLCYFNEDGFLYIVDRLKELIKYKGYQVPPAELEHILQSHPGIADAAVIPYPDEEAGELPMAFIVRQPGSNITKEQVMDYVAKQVAPYKKVRRVAFVTAIPKSPAGKILRRELVQQALSMGASKL +>SequenceA FromApisMellifera +MLPQTPDIIPTTLNQQKCVKARALYDNIAEAPDELAFRKGDVLTVLEQNTAGLEGWWLCALRGRQGICPGNRLRLLVGQYDTGGCLVGSRPDLTISEDGIQRHGKRRSWHVQPNRVVTPQKCGDVYLYDLPASRGSPAPPSRHDSPLNSNNEHLHNSGRYTTSSRNSVDNGGDVSDCYDVPPRAIPVIPSPASSPSPAPSCYDIPRPPTSCTPISNCSGGSGVTPLDCYDVPRPLQPLTPSSSASSLTNDGSLSGSNRSSLAAPDYDVPRSRLPASSLPSRHNTPVPKTPTPPPPPQTQQIYDVPVSKELPLELDSALEGLQRLQSEASAAIARLLGFVSPVWRTPQRLDATLMDLRLAALRLRTSLHDLAEFAEGTLGNAGKAPDKGLATKLRPLVKALRDSDKLVQEAATELDAMEWDAGKLCRGGGDTPTPTNGPPSTILPPAQPDPLDQLIACARALTEDVRQVASFIQGNSTLLFKRSSIISTGSSNNSGAGEDYDYVNLDSREVVAKQREEVRASLPQELRSNYDLLVSESDNATIQMPPTTPTPMDPNDKQLLAFYAAQVITHGNHLTHAIDAFMQTVEHNQPPKVFLAHGKFVVLSAHRLVHIGDTVHRNVIRNDVKTRVLECANALNEALKQTVSKTKQAAQFFPSVSAVQEMVDSVVDVSHLAKDLKVAIINGAQQPMEVTSSNFQEVLVELDEILKNATFLCIDGEFTGLNSGPDGGVFDTPAQYYAKLRTGSMDFLLIQFGLSVFTFNKEMQKYNQRSYNFYVFPRPLNRMAPDCRFMCQTSSISFLASQGFDFNKLFKLGIPYLTTNEEEKLMKRLEEKQRIRDEGTEILPISDVERPQIEEICSRIDEFVTSETEELLIEKCNAFIRRLVYQEVKLRWPNKLKVESKMNNFGCILVVQRLGTKEEEEQREIEKREREKTEIQQAVGLSILMRKIADSGKLIVGHNMLLDLCHIVHQFFGQLPESYFEFKSLVHSLFPRILDTKIICHSQQFKENIPSSNLGILLETVSKSPFKITEVEPIDGRSYSTLSEKCHEAGYDAYITGICFIALSNYLGSLQKPEVPIVLSDSPLLNPFLNKLLIARLKDVPYINLVGDDPNPSRDHVFHLTFPKEWKFNDISHLFSPFGSVHVSWLSDISAYIELHRRDQVNEVMKVLAKTSTYKLQRYADYQASLENFNTGERKRKLSSSEETTPEAEELCGCRECAKIETETLCRA diff --git a/2023/data/reference_assembly/output/scaffolds.fasta.gz b/2023/data/reference_assembly/output/scaffolds.fasta.gz new file mode 100644 index 00000000..af94fae4 Binary files /dev/null and b/2023/data/reference_assembly/output/scaffolds.fasta.gz differ diff --git a/2023/data/reference_assembly/reads.pe1.fastq.gz b/2023/data/reference_assembly/reads.pe1.fastq.gz new file mode 100644 index 00000000..2e9ec179 Binary files /dev/null and b/2023/data/reference_assembly/reads.pe1.fastq.gz differ diff --git a/2023/data/reference_assembly/reads.pe2.fastq.gz b/2023/data/reference_assembly/reads.pe2.fastq.gz new file mode 100644 index 00000000..ff7e7b97 Binary files /dev/null and b/2023/data/reference_assembly/reads.pe2.fastq.gz differ diff --git a/2023/data/reference_databases/DO_WHILE_BUILDING_IMAGE b/2023/data/reference_databases/DO_WHILE_BUILDING_IMAGE new file mode 100644 index 00000000..c5fcc8f7 --- /dev/null +++ b/2023/data/reference_databases/DO_WHILE_BUILDING_IMAGE @@ -0,0 +1,19 @@ +# get Swissprot/trembl + +mkdir uniprot +cd uniprot +wget ftp://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/complete/uniprot_sprot.fasta.gz +##wget ftp://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/complete/uniprot_trembl.fasta.gz + +gunzip uniprot_sprot.fasta.gz +makeblastdb -dbtype prot -parse_seqids -title "UniProtKB-SwissProt" -in uniprot_sprot.fasta +##makeblastdb -dbtype prot -parse_seqids -title "UniProtKB-TrEMBL" -in uniprot_trembl.fasta +##cd .. + + +### get NR +##mkdir nr +##cd nr +##./update_blastdb.pl nr + + diff --git a/2023/data/reference_databases/download_reference_databases b/2023/data/reference_databases/download_reference_databases new file mode 100644 index 00000000..c5fcc8f7 --- /dev/null +++ b/2023/data/reference_databases/download_reference_databases @@ -0,0 +1,19 @@ +# get Swissprot/trembl + +mkdir uniprot +cd uniprot +wget ftp://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/complete/uniprot_sprot.fasta.gz +##wget ftp://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/complete/uniprot_trembl.fasta.gz + +gunzip uniprot_sprot.fasta.gz +makeblastdb -dbtype prot -parse_seqids -title "UniProtKB-SwissProt" -in uniprot_sprot.fasta +##makeblastdb -dbtype prot -parse_seqids -title "UniProtKB-TrEMBL" -in uniprot_trembl.fasta +##cd .. + + +### get NR +##mkdir nr +##cd nr +##./update_blastdb.pl nr + + diff --git a/2023/data/reference_databases/update_blastdb.pl b/2023/data/reference_databases/update_blastdb.pl new file mode 100644 index 00000000..b71e25dc --- /dev/null +++ b/2023/data/reference_databases/update_blastdb.pl @@ -0,0 +1,271 @@ +#! /usr/bin/perl -w +# $Id: update_blastdb.pl,v 1.6 2005/09/09 18:58:39 camacho Exp $ +# =========================================================================== +# +# PUBLIC DOMAIN NOTICE +# National Center for Biotechnology Information +# +# This software/database is a "United States Government Work" under the +# terms of the United States Copyright Act. It was written as part of +# the author's official duties as a United States Government employee and +# thus cannot be copyrighted. This software/database is freely available +# to the public for use. The National Library of Medicine and the U.S. +# Government have not placed any restriction on its use or reproduction. +# +# Although all reasonable efforts have been taken to ensure the accuracy +# and reliability of the software and data, the NLM and the U.S. +# Government do not and cannot warrant the performance or results that +# may be obtained by using this software or data. The NLM and the U.S. +# Government disclaim all warranties, express or implied, including +# warranties of performance, merchantability or fitness for any particular +# purpose. +# +# Please cite the author in any work or product based on this material. +# +# =========================================================================== +# +# Author: Christiam Camacho +# +# File Description: +# Script to download the pre-formatted BLAST databases from the NCBI ftp +# server. +# +# =========================================================================== + +use strict; +use warnings; +use Net::FTP; +use Getopt::Long; +use Pod::Usage; +use File::stat; + +use constant VERSION => 1.2; +use constant NCBI_FTP => "ftp.ncbi.nlm.nih.gov"; +use constant BLAST_DB_DIR => "/blast/db"; +use constant USER => "anonymous"; +use constant PASSWORD => "anonymous"; +use constant DEBUG => 0; + +# Process command line options +my $opt_verbose = 1; +my $opt_quiet = 0; +my $opt_force_download = 0; +my $opt_help = 0; +my $opt_passive = 0; +my $opt_timeout = 120; +my $opt_showall = 0; +my $result = GetOptions("verbose+" => \$opt_verbose, + "quiet" => \$opt_quiet, + "force" => \$opt_force_download, + "passive" => \$opt_passive, + "timeout=i" => \$opt_timeout, + "showall" => \$opt_showall, + "help" => \$opt_help); +$opt_verbose = 0 if $opt_quiet; +die "Failed to parse command line options\n" unless $result; +pod2usage({-exitval => 0, -verbose => 2}) if $opt_help; +pod2usage({-exitval => 1, -verbose => 2}) unless (scalar @ARGV or $opt_showall); + + +# Connect and download files +my $ftp = &connect_to_ftp(); +if ($opt_showall) { + print "$_\n" foreach (sort(&get_available_databases())); +} else { + my @files = sort(&get_files_to_download()); + &download(@files); +} +$ftp->quit(); + +# Connects to NCBI ftp server +sub connect_to_ftp +{ + my %ftp_opts; + $ftp_opts{'Passive'} = 1 if $opt_passive; + $ftp_opts{'Timeout'} = $opt_timeout if ($opt_timeout >= 0); + $ftp_opts{'Debug'} = 1 if ($opt_verbose > 1); + my $ftp = Net::FTP->new(NCBI_FTP, %ftp_opts) + or die "Failed to connect to " . NCBI_FTP . ": $!\n"; + $ftp->login(USER, PASSWORD) + or die "Failed to login to " . NCBI_FTP . ": $!\n"; + $ftp->cwd(BLAST_DB_DIR); + $ftp->binary(); + print STDERR "Connected to NCBI\n" if $opt_verbose; + return $ftp; +} + +# Gets the list of available databases on NCBI FTP site +sub get_available_databases +{ + my @blast_db_files = $ftp->ls(); + my @retval = (); + + foreach (@blast_db_files) { + next unless (/\.tar\.gz$/); + push @retval, &extract_db_name($_); + } + + # Sort and eliminate adjacent duplicates + @retval = sort @retval; + my $prev = "not equal to $retval[0]"; + return grep($_ ne $prev && ($prev = $_, 1), @retval); +} + +# Obtains the list of files to download +sub get_files_to_download +{ + my @blast_db_files = $ftp->ls(); + my @retval = (); + + if (DEBUG) { + print STDERR "DEBUG: Found the following files on ftp site:\n"; + print STDERR "DEBUG: $_\n" for (@blast_db_files); + } + + for my $requested_db (@ARGV) { + for my $file (@blast_db_files) { + next unless ($file =~ /\.tar\.gz$/); + if ($file =~ /^$requested_db\..*/) { + push @retval, $file; + } + } + } + + if ($opt_verbose) { + for my $requested_db (@ARGV) { + unless (grep(/$requested_db/, @retval)) { + print STDERR "$requested_db not found, skipping.\n" + } + } + } + + return @retval; +} + +# Download the requestes files only if they are missing or if they are newer in +# the FTP site. +sub download($) +{ + my @requested_dbs = @ARGV; + + for my $file (@_) { + + if ($opt_verbose and &is_multivolume_db($file)) { + my $db_name = &extract_db_name($file); + my $nvol = &get_num_volumes($db_name, @_); + print STDERR "Downloading $db_name (" . $nvol . " volumes) ...\n"; + } + + if ($opt_force_download or + not -f $file or + ((stat($file))->mtime < $ftp->mdtm($file))) { + print STDERR "Downloading $file... " if $opt_verbose; + $ftp->get($file); + print STDERR "done.\n" if $opt_verbose; + } else { + print STDERR "$file is up to date.\n" if $opt_verbose; + } + } +} + +# Determine if a given pre-formatted BLAST database file is part of a +# multi-volume database +sub is_multivolume_db +{ + my $file = shift; + return 1 if ($file =~ /\.\d{2}\.tar\.gz$/); + return 0; +} + +# Extracts the database name from the pre-formatted BLAST database archive file +# name +sub extract_db_name +{ + my $file = shift; + my $retval = ""; + if (&is_multivolume_db($file)) { + $retval = $1 if ($file =~ m/(.*)\.\d{2}\.tar\.gz$/); + } else { + $retval = $1 if ($file =~ m/(.*)\.tar\.gz$/); + } + return $retval; +} + +# Returns the number of volumes for a BLAST database given the file name of a +# pre-formatted BLAST database and the list of all databases to download +sub get_num_volumes +{ + my $db = shift; + my $retval = 0; + foreach (@_) { + if (/$db/) { + if (/.*\.(\d{2})\.tar\.gz$/) { + $retval = int($1) if (int($1) > $retval); + } + } + } + return $retval + 1; +} + +__END__ + +=head1 NAME + +B - Download pre-formatted BLAST databases from NCBI + +=head1 SYNOPSIS + +update_blastdb.pl [options] blastdb ... + +=head1 OPTIONS + +=over 2 + +=item B<--showall> + +Show all available pre-formatted BLAST databases (default: false). The output +of this option lists the database names which should be used when +requesting downloads or updates using this script. + +=item B<--passive> + +Use passive FTP, useful when behind a firewall (default: false). + +=item B<--timeout> + +Timeout on connection to NCBI (default: 120 seconds). + +=item B<--force> + +Force download even if there is a archive already on local directory (default: +false). + +=item B<--verbose> + +Increment verbosity level (default: 1). Repeat this option multiple times to +increase the verbosity level (maximum 2). + +=item B<--quiet> + +Produce no output (default: false). Overrides the B<--verbose> option. + +=back + +=head1 DESCRIPTION + +This script will download the pre-formatted BLAST databases requested in the +command line from the NCBI ftp site. + +=head1 EXIT CODES + +This script returns 0 on success and a non-zero value on errors. + +=head1 BUGS + +Please report them to + +=head1 COPYRIGHT + +See PUBLIC DOMAIN NOTICE included at the top of this script. + +=cut diff --git a/2023/docs/images/aws_screenshot.png b/2023/docs/images/aws_screenshot.png new file mode 100644 index 00000000..c2db5419 Binary files /dev/null and b/2023/docs/images/aws_screenshot.png differ diff --git a/2023/docs/images/linux_find_terminal.png b/2023/docs/images/linux_find_terminal.png new file mode 100644 index 00000000..69bb9997 Binary files /dev/null and b/2023/docs/images/linux_find_terminal.png differ diff --git a/2023/docs/images/linux_login_done.png b/2023/docs/images/linux_login_done.png new file mode 100644 index 00000000..712bd9ae Binary files /dev/null and b/2023/docs/images/linux_login_done.png differ diff --git a/2023/docs/images/mobasession.PNG b/2023/docs/images/mobasession.PNG new file mode 100644 index 00000000..3601222f Binary files /dev/null and b/2023/docs/images/mobasession.PNG differ diff --git a/2023/docs/images/mobassh.PNG b/2023/docs/images/mobassh.PNG new file mode 100644 index 00000000..4afec09a Binary files /dev/null and b/2023/docs/images/mobassh.PNG differ diff --git a/2023/docs/images/session.PNG b/2023/docs/images/session.PNG new file mode 100644 index 00000000..cec4b7e5 Binary files /dev/null and b/2023/docs/images/session.PNG differ diff --git a/2023/docs/images/spotlight.png b/2023/docs/images/spotlight.png new file mode 100644 index 00000000..1796867d Binary files /dev/null and b/2023/docs/images/spotlight.png differ diff --git a/2023/docs/images/ssh_linux_login.png b/2023/docs/images/ssh_linux_login.png new file mode 100644 index 00000000..b9b02323 Binary files /dev/null and b/2023/docs/images/ssh_linux_login.png differ diff --git a/2023/docs/images/ssh_linux_username.png b/2023/docs/images/ssh_linux_username.png new file mode 100644 index 00000000..1ebacfad Binary files /dev/null and b/2023/docs/images/ssh_linux_username.png differ diff --git a/2023/docs/images/ssh_login.png b/2023/docs/images/ssh_login.png new file mode 100644 index 00000000..ba2d0770 Binary files /dev/null and b/2023/docs/images/ssh_login.png differ diff --git a/2023/docs/images/warning.png b/2023/docs/images/warning.png new file mode 100644 index 00000000..b5ef3439 Binary files /dev/null and b/2023/docs/images/warning.png differ diff --git a/2023/docs/images/warning_message.png b/2023/docs/images/warning_message.png new file mode 100644 index 00000000..9c5327b0 Binary files /dev/null and b/2023/docs/images/warning_message.png differ diff --git a/2023/docs/index.md b/2023/docs/index.md new file mode 100644 index 00000000..72bff5ad --- /dev/null +++ b/2023/docs/index.md @@ -0,0 +1,7 @@ +--- +layout: page +--- + + + +{% include_relative ssh.md %} \ No newline at end of file diff --git a/2023/docs/ssh.md b/2023/docs/ssh.md new file mode 100644 index 00000000..98216738 --- /dev/null +++ b/2023/docs/ssh.md @@ -0,0 +1,145 @@ +--- +layout: page +title: Tutorial - SSH +--- + +# SSH + +Click on the link to the operating system you are using + +[SSH on Linux](#sshlinux) + +[SSH on Mac](#sshmac) + +[SSH on Windows](#sshwindows) + +# SSH on Linux + +**Note:** Instructions are provided for **Ubuntu**, but if you are running a +different flavour of linux, the only thing that should be different is how to +open the terminal. From step 3 onwards, everything should be identical. + +1) On Ubuntu, click on the icon in the top left of the screen + +2) Type *Terminal* and open the terminal application + +![](images/linux_find_terminal.png) + +3) Into the Linux terminal that appears, type `ssh username@servername`, + replacing username and servername with the username and server name that you + have been emailed: + +```bash +ssh bt007@bt007.genomicscourse.com +``` + +1) The first time you log in, you will see a message talking about the host's + authenticity, it's fingerprint and asksing if you wish to continue. + +``` +The authenticity of host 'bt007.genomicscourse.com (192.135.232.24)' can't be established. +ECDSA key fingerprint is SHA256:xmvrB9Ke/bXNtpu5PXF6IbUS8wxCtF6SNqZ7VV+IRoU. +Are you sure you want to continue connecting (yes/no)? +``` + +This message is normal when you log in to a new server. Agreeing will store the server's fingerprint, and the message will not appear again. + +1) Type `yes` into the Linux terminal and hit return. + +2) You will then be asked for a password. + +``` +bt007@bt007.genomicscourse.com's password: +``` + +Type in the password that you've been emailed, and hit return. Nothing will appear while you type. If you know you have made a mistake, you can hold down backspace, and retype the password. + +7) Congratulations! You are now logged in! + +# SSH on Mac + +1) Press Cmd-Space to open Spotlight, type *Terminal*, and press enter. + +![](images/spotlight.png) + +2) Into the Mac terminal that appears, type `ssh username@servername`, replacing username and servername with the username and server name that you have been emailed: + +``` +ssh bt007@bt007.genomicscourse.com +``` + +3) The first time you log in, you will see a message talking about the host's authenticity, it's fingerprint and asksing if you wish to continue. + +``` +The authenticity of host 'bt007.genomicscourse.com (192.135.232.24)' can't be established. +ECDSA key fingerprint is SHA256:xmvrB9Ke/bXNtpu5PXF6IbUS8wxCtF6SNqZ7VV+IRoU. +Are you sure you want to continue connecting (yes/no)? +``` + +This message is normal when you log in to a new server. Agreeing will store the server's fingerprint, and the message will not appear again. + + +4) Type `yes` into the Mac terminal and press enter. + + +5) You will then be asked for a password. + +``` +bt007@bt007.genomicscourse.com's password: +``` + +Type in the password that you've been emailed, and hit return. Nothing will appear while you type. If you know you have made a mistake, you can hold down backspace, and retype the password. + +6) Congratulations! You are now logged in! + + +# SSH on Windows + +## Installing MobaXTerm + +There are a number of SSH clients you can use, but for the purposes of this practical, we would recommend MobaXTerm. + +1) Download MobaXTerm from: + - select installer version. + +2) Unzip the folder you downloaded. + +3) Run the file ending in .msi - you'll get a windows prompt to install this, which it is safe to agree to. Install MobaXTerm in the default location, and you're then ready to log in. + +## Logging in through MobaXTerm + +1) Open MobaXTerm from the Windows start menu (if you can't find it, use the search bar). + +2) Click on Session in the upper left of MobaXTerm ![](images/mobasession.PNG) + +3) Select SSH in the window that opens. + +4) In the next window, enter your computer's hostname in the `Remote host` box + (your computer's hostname is included in the email that we sent you with log + in details). + +5) In the same window, tick the `Specify username` box, and add your username + (included in the email that we sent you with log in details). + +![](images/ssh_login.png) + + +1) Tick OK, at the bottom of the box. + +2) You may see a message the first time you log in, saying that "the authenticity of the host can not be established", and asking if you wish to continue connecting. This message is normal when you log in to a new server. Agreeing will store the server's fingerprint, and the message will not appear again. + +3) Click on `Yes` if the message appears + +![](images/warning.png) + + + +9) You will then be asked for a password. + +``` +james@james.genomicscourse.com's password: +``` + +Type in the password that you've been emailed, and press enter. Nothing will appear while you type. If you know you have made a mistake, you can hold down backspace, and retype the password. + +10) Congratulations! You are now logged in! diff --git a/2023/practicals/img/Queen_Mary,_University_of_London_logo.svg b/2023/practicals/img/Queen_Mary,_University_of_London_logo.svg new file mode 100644 index 00000000..6e2c1200 Binary files /dev/null and b/2023/practicals/img/Queen_Mary,_University_of_London_logo.svg differ diff --git a/2023/practicals/population_genetics/README.md b/2023/practicals/population_genetics/README.md new file mode 100644 index 00000000..60922e07 --- /dev/null +++ b/2023/practicals/population_genetics/README.md @@ -0,0 +1,8 @@ +# Genome-Bioinformatics: read mapping, variant calling and population genetics + +Practical aimed at getting students familiar with: +* Concept of variants and variant calling +* Read mapping +* Simple pipelines +* Standard formats: VCF and SAM/BAM +* An example of biological analysis diff --git a/2023/practicals/population_genetics/popgen.Rmd b/2023/practicals/population_genetics/popgen.Rmd new file mode 100644 index 00000000..3c6cf9f1 --- /dev/null +++ b/2023/practicals/population_genetics/popgen.Rmd @@ -0,0 +1,308 @@ +# Population genetics in R + +## Introduction + +We have samples with two genotypes: the B genotype (associated with single-queen colony phenotype) and the b genotype (found exclusively in multiple-queen colonies). + +Our dummy assembly has two scaffolds, from two different chromosomes. We aim to test whether any parts of this assembly differ between the individuals from these two groups (B and b). + +First, we will create a heat map of the genotypes of the individuals and we will run Principal Component Analysis (PCA) on these genotypes. This will allow us to visualise if individuals cluster together by their B/b genotype. This will be done using the ``adegenet`` package in R. + +In a second part, we are going to measure genetic differentiation between the two groups (B and b). We will do this analysis over a sliding window, to see if the differentiation between B and b are specific to any portion of the genome. We will also measure the genetic diversity among each of the groups, which may tell us something about the evolutionary history of the portions of genome represented in our assembly. This will be done using the ``PopGenome`` package in R. + +## Load packages + +Before we start with the analysis, let us first load the R packages we will need and configure them. + +```{r message=FALSE} +# Load libraries +library(dplyr) +library(ggplot2) +library(adegenet) +library(PopGenome) + +# Configure ggplot to use 'theme_minimal' +theme_set(theme_minimal()) +``` + +## Analysis using ``adegenet`` + +The package ``adegenet`` uses an R object called ``genlight``. To create it, we need to input a matrix where each row is an individual and each column is a locus (i.e. a SNP position). We can do this using ``bcftools``: + +```{bash engine.opts='-l'} +# Select the information in the vcf file without the header +bcftools query input/snp.vcf.gz -f '%CHROM\t%POS[\t%GT]\n' > snp_matrix.txt + +# Get sample names +bcftools query -l input/snp.vcf.gz | sed 's/.bam//g' > sample_names.txt +``` + +Next, create the R ``genlight`` object from the files we just created: + +```{r} +# Input the SNP data and the sample names by reading the .txt files you just created with bcftools +names_input <- read.table("sample_names.txt", col.names = c("names")) +sample_names <- as.vector(names_input$names) + +snp_data <- read.table("snp_matrix.txt") +colnames(snp_data) <- c("scaffold", "position", sample_names) + +# Keep the position of the loci +loci <- snp_data[, c("scaffold", "position")] + +# Transpose the data (turn it on its side so that rows = individuals and columns = loci) +snp_matrix <- t(snp_data[,3:ncol(snp_data)]) + +# Finally we reorder the rows by population +bb <- sample_names[grep(pattern = "B", x = sample_names)] # B samples (bb = "big B") +lb <- sample_names[grep(pattern = "b", x = sample_names)] # b samples (lb = "little b") +snp_matrix <- snp_matrix[c(bb, lb), ] + +# Now we can create a new genlight object that contains all the SNP data. Note that the +# following line has been split up over multiple lines to make it easier to read R won't +# run the command until all brackets have been closed. +snp <- new("genlight", + snp_matrix, + chromosome = loci$scaffold, + position = loci$position, + pop = as.factor(c(rep("B", 7), rep("b", 7)))) + + +# Print details of the snp genlight object: +snp +``` + +You can access the content of ``snp`` object using the "@" sign: + +```{r} +# Print name of the individuals: +snp@ind.names + +# There are some functions that may also be helpful: +ploidy(snp) +``` + +Now plot a heatmap showing the genotypes. + +```{r} +## Heat map of genotype +glPlot(snp) +``` + +You can also perform a Principle Component Analysis (PCA) and plot the first few components. + +```{r} +## PCA +# Run PCA - scale = TRUE meaning any outlier will be accounted for, recommended if no previous normalisation was applied to the data +pca_results <- prcomp(snp_matrix, scale. = TRUE) +# Check how much variance each PC explains +summary(pca_results) +# Call out another dimension of the data +pca_results_invert <- as.data.frame(pca_results$x) +# Add additional column with B or b to set colours in the plot +pca_results_invert$sample <- rownames(pca_results_invert) +# Plot the PCA +pca_plot <- pca_results_invert %>% + mutate_all(~ gsub(pattern = "results/|f1|f2|f3|f4|f5|f6|f7|_", replacement = "", .)) %>% # Remove redundant pattern from the data to only have B or b + transform(pca_results_invert, # Transform values to numeric + PC1 = as.numeric(PC1), + PC2 = as.numeric(PC2), PC3 = as.numeric(PC3) +) %>% + ggplot(aes(x = PC1, y = PC2, colour = sample)) + # Plot 2 first PC values + geom_point(size = 2) + + xlab("PC1") + + ylab("PC2") + + coord_fixed(ratio = 1) + +pca_plot +``` + +The aim of these analyses is to test whether the B and the b individuals cluster together or separately. The first principal component separates B and b. But if you look at the heat map, the separation is not constant in the whole genome. + +Each of the scaffolds is from a different chromosome. We can test whether the differentiation between B and b is only seen in one of the scaffolds. + +We will start with scaffold_2. + +```{r} +## scaffold_2 +# Plot heat map +scaffold_2 <- snp[, which(snp@chromosome == "scaffold_2")] +glPlot(scaffold_2) + +# Plot PCA +# Select only "scaffold_2" rows +scaffold_2_pca <- snp_data %>% dplyr::group_by(scaffold) %>% dplyr::filter(scaffold == "scaffold_2") +# Transpose the data +scaffold_2_pca <- t(scaffold_2_pca[, 3:ncol(scaffold_2_pca)]) +scaffold_2_pca_res <- prcomp(scaffold_2_pca, scale. = TRUE) +# Check how much variance each PC explains +summary(scaffold_2_pca_res) +# Call out another dimension of the data +scaffold_2_pca_inv <- as.data.frame(scaffold_2_pca_res$x) +# Add additional column with B or b to set colours in the plot +scaffold_2_pca_inv$sample <- sample_names +# Plot the PCA +scaffold_2_pca_plot <- scaffold_2_pca_inv %>% + mutate_all(~ gsub(pattern = "results/|f1|f2|f3|f4|f5|f6|f7|_", replacement = "", .)) %>% # Remove redundant pattern from the data to only have B or b + transform(pca_results_invert, # Transform values to numeric + PC1 = as.numeric(PC1), + PC2 = as.numeric(PC2), PC3 = as.numeric(PC3) +) %>% + ggplot(aes(x = PC1, y = PC2, colour = sample)) + + geom_point(size = 2) + + xlab("PC1") + + ylab("PC2") + + coord_fixed(ratio = 1) + +scaffold_2_pca_plot +``` + +Now check scaffold_1. +```{r} +## scaffold_1 +# Plot heat map +scaffold_1 <- snp[, which(snp@chromosome == "scaffold_1")] +glPlot(scaffold_1) + +# Plot PCA +scaffold_1_pca <- snp_data %>% dplyr::group_by(scaffold) %>% dplyr::filter(scaffold == "scaffold_1") +scaffold_1_pca <- t(scaffold_1_pca[, 3:ncol(scaffold_1_pca)]) +scaffold_1_pca_res <- prcomp(scaffold_1_pca, scale. = TRUE) +summary(scaffold_1_pca_res) + +scaffold_1_pca_inv <- as.data.frame(scaffold_1_pca_res$x) +scaffold_1_pca_inv$sample <- sample_names + +scaffold_1_pca_plot <- scaffold_1_pca_inv %>% + mutate_all(~ gsub(pattern = "results/|f1|f2|f3|f4|f5|f6|f7|_", replacement = "", .)) %>% + transform(pca_results_invert, + PC1 = as.numeric(PC1), + PC2 = as.numeric(PC2), PC3 = as.numeric(PC3) +) %>% + ggplot(aes(x = PC1, y = PC2, colour = sample)) + + geom_point(size = 2) + + xlab("PC1") + + ylab("PC2") + + coord_fixed(ratio = 1) + +scaffold_1_pca_plot +``` +* Is differentiation coming mainly from one of the scaffolds? +* If so, which one? + +## Using ``PopGenome`` to measure differentiation and diversity + +Another way of measuring differentiation between groups of individuals is using the fixation index, FST, which tests whether there is genetic structure in the population. FST can be used, for example, to test whether there is evidence of low gene flow between populations. In the case of the fire ant, the B and b supergene variants coexist in the population, but do not recombine with each other - so they should show strong differentiation. + +An important population genetics measure is genetic diversity. Patterns of genetic diversity can be informative of a population's evolutionary past - for example, low genetic diversity may be evidence for a recent population bottleneck. Furthermore, the variation of diversity within the genome can be informative of different evolutionary effects, such as the strength of selection in different parts of the genome. + +We will measure FST and nucleotide diversity (a measure of genetic diversity) using the R package ``PopGenome``. + +In theory, ``PopGenome`` can read VCF files directly, using the ``readVCF`` function. However, because our samples are haploid, we need to use a different function, ``readData``, which requires a folder with a separate VCF for each scaffold. + +```{bash engine.opts='-l'} +# Make new directory +mkdir -p popgenome-vcf + +# Separate variant sites for each scaffold into different files. +bcftools view input/snp.vcf.gz scaffold_1 > popgenome-vcf/scaffold_1 +bcftools view input/snp.vcf.gz scaffold_2 > popgenome-vcf/scaffold_2 +``` + +Now we can analyse the data: + +```{r} +# Load the data +# MODIFY the path for the above created folder +snp <- readData("popgenome-vcf", format = "VCF") + +# This is complex object, with several slots +get.sum.data(snp) +show.slots(snp) + +# You can access the different "slots" by using the "@" sign: +snp@n.sites + +# Set populations +pops <- get.individuals(snp)[[1]] +pop1 <- pops[grep(pattern = "B\\.bam", x = pops)] +pop2 <- pops[grep(pattern = "b\\.bam", x = pops)] + +snp <- set.populations(snp, list(pop1, pop2)) + +snp@populations # check if it worked +``` + +Let's calculate FST between the two populations and nucleotide diversity in each of the populations. + +```{r} +# Diversities and FST (by scaffold) +snp <- F_ST.stats(snp) # this does the calculations and + # adds the results to the appropriate slots + +# Print FST +get.F_ST(snp) # each line is a scaffold +snp@nucleotide.F_ST + +# Print diversities +get.diversity(snp) +get.diversity(snp)[[1]] # pop1 (B) +get.diversity(snp)[[2]] # pop2 (b) +snp@nuc.diversity.within +``` + +Another useful tool is to do the calculations along a sliding window. + +```{r} +# Transform object into object divided by sliding window +win_snp <- sliding.window.transform(snp, + width = 10000, + jump = 10000, + type = 2, + whole.data = FALSE) + +# Measurements per window +win_snp <- F_ST.stats(win_snp) + +win_snp@nucleotide.F_ST +win_snp@nuc.diversity.within +``` + +Now we can look at the FST for each window. + +```{r} +# A simple plot +win_fst <- win_snp@nucleotide.F_ST[, 1] + +ggplot(data = data.frame(window = 1:length(win_fst), value = win_fst)) + + geom_point(aes(x = window, y = value)) + + xlab("Window") + + ylab("FST per window") +``` + +Diversity among B individuals. + +```{r} +# diversity among B (bb = "big B") +bb_div <- win_snp@nuc.diversity.within[, 1] + +ggplot(data = data.frame(window = 1:length(bb_div), value = bb_div)) + + geom_point(aes(x = window, y = value)) + + xlab("Window") + + ylab("Diversity among B") +``` + +Diversity among b individuals. + +```{r} +# diversity among b (lb = "little b") +lb_div <- win_snp@nuc.diversity.within[, 2] + +ggplot(data = data.frame(window = 1:length(lb_div), value = lb_div)) + + geom_point(aes(x = window, y = value)) + + xlab("Window") + + ylab("Diversity among b") +``` + +* Knowing that there is no recombination between B and b somewhere in the genome, why do you think there is high FST in one scaffold and not the other? +* What factors could make b have such low diversity in one of the scaffolds? diff --git a/2023/practicals/population_genetics/pt-4-map-call.md b/2023/practicals/population_genetics/pt-4-map-call.md new file mode 100644 index 00000000..8e7fde4c --- /dev/null +++ b/2023/practicals/population_genetics/pt-4-map-call.md @@ -0,0 +1,435 @@ +--- +layout: page +title: Part 4 - Read mapping and variant calling +--- + + + +# Part 4: Population genetics - Read mapping and variant calling + +## 1. Introduction + +Different types of genetic variants exist. Commonly, people look at **single +nucleotide polymorphisms** (**SNPs**, sometimes also known as **single +nucleotide variants**, **SNVs**). Other classes include small insertions and +deletions (known collectively as **indels**), as well as larger structural +variants, such as large insertions, deletions, inversions and translocations. Some +of these larger ones are described as **copy number variants**, **CNVs**). + +Here, we aim to identify genetic variation and genotypes from **short +paired-end Illumina reads**. First, we will map the reads from each +individual to a reference assembly similar to the one created in the +[previous practical](../reference_genome/pt-2-assembly.md) (you can use your +assembly too, but that is better left as an exercise for later!). Then we will +find the positions where at least some of the individuals differ from the +reference genome sequence (and from each other). + +## 2. Pipeline + +We will analyse subsets of whole-genome sequences of several fire ant +individuals. The fire ant, *Solenopsis invicta*, is notable for having two colony +types, with some colonies having one queen and other +colonies having multiple queens. Previous work showed that this trait is +associated with the **B** vs. **b** alleles of a genetic marker. In this +practical, we aim to understand whether there are multiple genetic differences +between B and b ants. As a reminder, all ants in single queen colonies carry the B +allele of the genetic marker, while individuals carrying the b alelles exist +exclusively in multiple queen colonies. + +We will use a subset of the reads from whole-genome sequencing of 14 male fire +ants. Samples 1B to 7B are from single-queen colonies, samples 1b to 7b are from +multiple-queen colonies. Ants are haplodiploid, which means that females are +diploid and males are haploid. Here we will use only males, so all our samples +are haploid, which makes variant calling easier. Bacteria and yeast are +typically also haploid. For highly inbred strains of many laboratory organisms, most +of the genome similarly lacks genetic diversity. + +The aim of this practical is to genotype these 14 individuals. We will: + +1. Align the reads of each individual to a reference genome assembly using the + aligner *bowtie2*. +2. Find positions that differ between each individual and the reference with + the software *samtools* and *bcftools*. +3. Filter the SNP calls to produce a set of good-quality SNPs. +4. Visualise the alignments and the SNP calls in the genome browser *IGV*. + +We recommend that you create a directory for this work following the same +principles as in the last few practicals (e.g., `2023-10-02-mapping`). You +should have subdirectories called `input`, `results` and `tmp` and a +`WHATIDID.txt` file in which to log your commands. +Create a symlink (using `ln -s`) from the reference genome +`/shared/data/popgen/reference.fa` and the directory containing the reads +`/shared/data/popgen/reads` to `input` subdirectory: + +> **_Note:_** +> Remember to keep your commands in the `WHATIDID.txt` file. + +```bash +2023-10-02-mapping/ +├── input +│   ├── -> /shared/data/popgen/reference.fa +│   └── -> /shared/data/popgen/reads +├── results +├── tmp +└── WHATIDID.txt +``` + +To check that the reference genome and the reads directory are linked +(not copied) in the `input` directory, you could use one of the following +commands from your `input` directory: + +```bash +ls -al +``` + +Check how many scaffolds there are in the reference genome: + +```bash +grep "^>" input/reference.fa +``` + +> **_Question:_** +> Have a look at the `.fq.gz` files (`ls input/reads`). +> +> * Why does each sample have two sets of reads? +> * What is each line of the `.fq.gz` file? (you can use `zless`) +> * How many reads do we have in individual *f1_B*? (you can use `zless` and + `wc -l`) +> * How long are the reads (are all their lengths equal)? +> * Knowing that each scaffold is 200kb, calculate which coverage you would expect per base +> pair of individual *f1_B*? + +## 3. Aligning reads to a reference assembly + +The first step in our pipeline is to align the paired end reads to the reference +genome. We are using the software [*bowtie2*](http://bowtie-bio.sourceforge.net/bowtie2/index.shtml), +which was created to align short read sequences to long sequences such as the +scaffolds in a reference assembly. Like most aligners, *bowtie2* works in two +steps: + +1. the scaffold sequence (sometimes known as the database) is indexed, in this + case using the + [Burrows-Wheeler Transform](https://en.wikipedia.org/wiki/Burrows-Wheeler_transform). + This manner of representing the genome enables it to be stored using less memory, and + thus enables memory-efficient alignment of sequence reads to the reference. +2. Only subsequently will we do the actual alignment of Illumina reads from individual samples to the indexed reference genome. + +Let's start by linking scaffold sequences to our `tmp` directory. + +Symlink `reference.fa` to `tmp/`: + +```bash +cd tmp +ln -s ~/2023-10-02-mapping/input/reference.fa . +cd .. +``` + +Build the index (step 1): + +```bash +bowtie2-build tmp/reference.fa tmp/reference +``` + +Perform the alignment (step 2): + +```bash +# Create a directory for the alignments. +mkdir tmp/alignments + +# Use bowtie2 to align paired reads from f1_B sample to the reference. +bowtie2 --local -x tmp/reference -1 input/reads/f1_B.1.fq.gz -2 input/reads/f1_B.2.fq.gz > tmp/alignments/f1_B.sam +``` + +> **_Question:_** +> * What is the meaning of the `-1` and `-2` parameters? +> * Why do we use `--local` parameter? + +The command produced a *SAM* file ( +[Sequence Alignment/Map file](http://samtools.github.io/hts-specs/SAMv1.pdf)), +which is a text representation of the standard format used to store sequence alignments. +Have a quick look at the file using `less`. The file includes a header (lines +starting with the `@` symbol), and a line for every read aligned to the +reference assembly. For each read, we are given a mapping quality value, the +position of both reads in a pair, the actual sequence and its quality by base +pair, and a series of flags with additional measures of mapping quality. + +> **_Question:_** +> Can you tell, by looking at the *SAM* file specification linked above, +> which columns correspond to which information? + +We now need to run *bowtie2* for all the other samples. We could do this by +typing the same command another 13 times (changing the sample name). Alternatively, we can +use [*GNU parallel*](https://www.gnu.org/software/parallel/), a tool that helps +to automatce running the same command on several samples. + +To use `parallel`, lets first create a file that contains all sample names: + +```bash +ls input/reads/*fq.gz | cut -d '/' -f 3 | cut -d '.' -f 1 | sort | uniq > tmp/names.txt +``` + +Then, run *bowtie* on each sample (will take a few minutes): + +```bash +cat tmp/names.txt | parallel --verbose --jobs 1 "bowtie2 --local -x tmp/reference -1 input/reads/{}.1.fq.gz -2 input/reads/{}.2.fq.gz > tmp/alignments/{}.sam" +``` + +Because the *SAM* files include a lot of information, they tend to occupy a lot +of space (even with our small example data). Therefore, *SAM* files are +generally compressed into *BAM* files (Binary sAM). Most tools that use aligned +reads require BAM files that have been sorted and indexed by genomic position. +This is done using [*samtools*](http://www.htslib.org/doc/samtools.html), a +set of tools created to manipulate *SAM*/*BAM* files. + +First, sort the SAM file by scaffold position and output in BAM format: + +```bash +samtools sort -O BAM tmp/alignments/f1_B.sam > tmp/alignments/f1_B.bam +``` + +Then, index the BAM file generated above (creates f1_B.bam.bai): + +```bash +samtools index tmp/alignments/f1_B.bam +``` + +Also in this case, we can use `parallel` to run this step for all the samples: + +```bash +# For each sample, sort the SAM file for each and convert to BAM. +cat tmp/names.txt | parallel --verbose "samtools sort -O BAM tmp/alignments/{}.sam > tmp/alignments/{}.bam" + +# Index the BAM file for each sample. +cat tmp/names.txt | parallel --verbose "samtools index tmp/alignments/{}.bam" +``` + +Now check that a `.bam` and a `.bai` file exist for each sample. + +To view what's in a *BAM* file, you have to use `samtools view`: + +```bash +# View the entire BAM file: +samtools view tmp/alignments/f1_B.bam | less -S + +# View a particular region of the reference: +samtools view tmp/alignments/f1_B.bam scaffold_1:10000-10500 | less -S +``` + +Copy the `.bam` and `.bai` files to the `results` directory. + +```bash +cp tmp/alignments/*.bam results/ +cp tmp/alignments/*.bai results/ +``` + +Once you are sure the files are in `results`, clean the `tmp` directory. + +```bash +rm -ri tmp +``` + +## 4. Variant calling + +Create a new directory in your `home` for the second part of today's practical +(e.g., `2023-10-02-genotyping`). You will want to set up the relevant +subdirectories and `WHATIDID.txt` file as before. Then symlink (`ln -s`) the +reference genome `/shared/data/popgen/reference.fa` and the alignments +from the mapping part of the practical (both `.bam` and `.bai` files) to your +`input` directory. + +> **_Note:_** +> Remember to keep your commands in the `WHATIDID.txt` file. + +This is what your directory structure should look like when running `tree`: + +```bash +2023-10-02-genotyping/ +├── input +│   ├── -> /shared/data/popgen/reference.fa +│   ├── -> ~/2023-10-02-mapping/results/f1_B.bam +│   ├── -> ~/2023-10-02-mapping/results/f1_B.bam.bai +│   └── -> ... +├── results +├── tmp +└── WHATIDID.txt +``` + +Several variant calling approaches exist. The simplest approach is to look +for positions where the mapped reads consistently have a different base than the +reference assembly (this is called **consensus approach**). For this, we will +use [*bcftools*](http://www.htslib.org/doc/bcftools.html), a set of tools to +call variants and manipulate them. We will run two commands: + +```bash +bcftools mpileup +``` + +The previous command looks for inconsistencies between the reference and the +aligned reads, followed by: + +```bash +bcftools call +``` + +which interprets them as variants. + +We will use *multiallelic caller* (option `-m`) of `bcftools` and set all +individuals as **haploid**. + +First link `reference.fa` to `tmp/` + +```bash +cd tmp +ln -s ~/2023-10-02-genotyping/input/reference.fa . +cd .. +``` + +Then create the index of the reference (different from that used by *bowtie2*): + +```bash +samtools faidx tmp/reference.fa +``` + +Finally, call the variants using *bcftools*: identify all differences between +reference and reads using `mpileup` subcommand and pipe it to call subcommand +to determine if the identified difference are variants. + +```bash +bcftools mpileup --output-type u --fasta-ref tmp/reference.fa input/*.bam | bcftools call --ploidy 1 --variants-only --multiallelic-caller > tmp/calls.vcf +``` + +> **_Question:_** +> +> * Why we are using the `--variants-only` option in `bcftools call`? +> * Is it ever useful to leave it out? + +The output `calls.vcf` is a file in the *VCF* +([Variant Call Format](http://samtools.github.io/hts-specs/VCFv4.3.pdf)) format, +which contains the position, nature and quality of the called variants. + +> **_Note:_** +> Check that the output VCF file has the right extension `.vcf`: +> +> ```bash +> ls tmp/calls* +> ``` +> +> If the listed file has a different name from the expected `calls.vcf`, rename +> it by running the command: +> +> ```bash +> mv tmp/YOUR_CALLS_FILENAME tmp/calls.vcf +> ``` +> +> where you need to substitute YOUR_CALLS_FILENAME with the filename you got +> from the `ls tmp/calls*` command. + +Let's take a look at the *VCF* file produced by typing `less -S tmp/calls.vcf`. +The file is composed of a header and rows for all the variant positions. Have a +look at the different columns and check what each is (the header includes +labels). Notice that some columns include several fields. + +> **_Question:_** +> * Where does the header start and end? +> * How is the genotype of each sample coded? +> * How many variants were identified? +> * Can you tell the difference between SNPs and indels? How many of each have +> been identified? + +## 5. Quality filtering of variant calls + +Some potentially identified genetic variation may be unreliable - for example due +to sequencing errors or ambiguous mapping. The VCF file includes several fields with +quality information that enable us to remove lower-confidence genetic variants. +The most obvious is the column QUAL, which provides a +[Phred-scale quality score](https://en.wikipedia.org/wiki/Phred_quality_score) for +each genetic variant. + +* What does a Phred-scale quality score of 30 mean? + +We will filter the VCF using `bcftools filter`. Based on the distribution of quality values we +see in the file, we suggest removing variant with a quality less than **30**: + +```bash +# Remove variant site with quality score less than 30. Then remove sites that have a missing genotype call. +bcftools filter --exclude 'QUAL < 30' tmp/calls.vcf | bcftools view --genotype ^miss > tmp/filtered_calls.vcf +``` + +In real scenarios, it may be important to filter by other parameters, but we will also use a different +variant calling & genotyping approach. bcftools is not normally used for real projects. + +In the downstream analysis, we only want to look at sites that are: + +1. snps (--types snps) +2. biallelic (--min-alleles 2 --max-alleles 2) +3. where the minor allele is present in at least one individual (because we are + not interested in the sites where all individuals are different from the + reference, yet equal to each other) + +Now, select **biallelic** variant sites that are SNPs and at least one +individual differs from the rest: + +```bash +bcftools view --types snps --min-alleles 2 --max-alleles 2 --min-ac 1:minor tmp/filtered_calls.vcf > tmp/snp.vcf +``` + +(Always check that the output file in `tmp` has the right extension `.vcf`) + +> **_Question:_** +> * How many SNPs does the resulting *VCF* file have? +> * Can you find any other parameters indicating the quality of the site? +> * Can you find any other parameters indicating the quality of the variant call +> for a given individual on a given site? + +In this practical, we only looked at a subset of the fire ant genome. When +calling variants for the entire genome and using hundreds or thousands of +samples, the resulting VCF files can end up being very large (reaching terabytes +for cancer genomics projects!). It is thus a good idea to compress and index a +*VCF* file. This is typically done using `bgzip` (for compression) and `tabix` +(for indexing - tabix requires the file to be compressed using `bgzip`). + +Compress the VCF file using `bgzip`. This will remove the `snp.vcf` file and +produce `snp.vcf.gz` file in its place: + +```bash +bgzip tmp/snp.vcf +``` + +Index the compressed *VCF* file. This will produce a `.tbi` file alongside the +`snp.vcf.gz` file. + +```bash +tabix tmp/snp.vcf.gz +``` + +Now that we have a SNP set, we can copy it to `results` directory: + +```bash +cp tmp/snp.vcf.gz results +cp tmp/snp.vcf.gz.tbi results +``` + +## 6. Viewing the results using IGV (Integrative Genome Viewer) + +In this part of the practical, we will use the software [*IGV*](https://igv.org) +to visualise the alignments and the SNPs we generated, and verify some of the +called SNPs. + +1. Copy the *BAM* and their index files (`.bai`) to `~/www/igv/data`. +2. Copy the `snp.vcf.gz` and its index file (`.tbi`) to `~/www/igv/data`. + +To visualise them, open *IGV* by clicking on the *IGV* link in your personal +module page (e.g., http://bob.genomicscourse.com). + +Here, we use [*igv.js*](https://github.com/igvteam/igv.js#igvjs) which is +designed to be embedded in web pages and the installation is pre-configured to +use the assembly (`reference.fa` file) you used for variant calling. + +> **_Questions:_** +> +> * Try to undrestand what all the parts of the screen are and mean. +> * What do the colors represent? +> * Can you see genetic variation? Can you see sequencing errors? +> * Has bcftools/mpileup recovered the same genetic variants as you would by looking +> at the alignments with IGV? +> * Do you think our filtering was effective? diff --git a/2023/practicals/population_genetics/pt-5-popgen.md b/2023/practicals/population_genetics/pt-5-popgen.md new file mode 100644 index 00000000..b0f1fad8 --- /dev/null +++ b/2023/practicals/population_genetics/pt-5-popgen.md @@ -0,0 +1,61 @@ +--- +layout: page +title: Part 5 - Population genetics in R +--- + + + +# Part 5 - Population genetics in R + +## 1. Introduction + +In this practical, we will use samples with two genotypes associated to two +distinct phenotypes. Also, Our example assembly consists of two scaffolds, +from two different chromosomes: + +| Genotype label | Phenotype description | +| :------------: | :---------------------: | +| *B* | *single-queen* colony | +| *b* | *multiple-queen* colony | + + +The aim of our analysis is to test whether any parts of this assembly differ +between the individuals from these two groups (*B* and *b*). + +In the first part of the analysis, we are going to create a heat map of the +genotypes of the individuals and we are going to run Principal Component +Analysis (PCA) on these genotypes. This will allow us to test if any of the +individuals cluster together by their B/b genotype. This will be done using +the *adegenet* package in R. + +In the second part, we are going to estimate the genetic differentiation between +the two groups (*B* and *b*). We will do this analysis over a sliding window, +to see if the differentiation between *B* and *b* are specific to any portion of +the genome. We will also measure the genetic diversity among each of the groups, +which may tell us something about the evolutionary history of the portions of +genome represented in our assembly. This will be done using the *PopGenome* +package in R. + +## 2. Input into R + +As before, create a directory for this practical (e.g., +`2023-10-xx-population_genetics`). Copy over the R markdown notebook +`/shared/data/popgen/popgen.Rmd` to your project directory. Create `input/` +subdirectory and symlink the `snp.vcf.gz` and `snp.vcf.gz.tbi` file we created +in the last practical to it. If you don't have these files, you can use the +ones in: `/shared/data/backup_vcf`. +The output of the `tree` command should look like this: + +```bash +2023-10-xx-population_genetics +├── input +│   ├── snp.vcf.gz +│   └── snp.vcf.gz.tbi +└── popgen.Rmd +``` + +Next, open *RStudio* by clicking on the 'RStudio' link in your personal module +page (e.g., bt007.genomicscourse.com). Login using your username (e.g., bt007) +and the password that you use for ssh. +In *RStudio*, open the file `popgen.Rmd` and work through the rest of the +practical there. diff --git a/2023/practicals/reference_genome/README.md b/2023/practicals/reference_genome/README.md new file mode 100644 index 00000000..bfffa6b0 --- /dev/null +++ b/2023/practicals/reference_genome/README.md @@ -0,0 +1,8 @@ +## Read cleaning, genome assembly (and quality assessment) & gene prediction + +Pdfs for manual assembly exercise [here](paper_exercise) + +Main documents: +[Part 1: Read cleaning](pt-1-read-cleaning.md) +[Part 2: Genome assembly](pt-2-assembly.md) +[Part 3: Gene prediction](pt-3-prediction.md) diff --git a/2023/practicals/reference_genome/img-qc/bad.png b/2023/practicals/reference_genome/img-qc/bad.png new file mode 100644 index 00000000..8a1b553a Binary files /dev/null and b/2023/practicals/reference_genome/img-qc/bad.png differ diff --git a/2023/practicals/reference_genome/img-qc/good.png 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00000000..d071e390 Binary files /dev/null and b/2023/practicals/reference_genome/img/yannick-overview.png differ diff --git a/2023/practicals/reference_genome/paper_exercise/README.md b/2023/practicals/reference_genome/paper_exercise/README.md new file mode 100644 index 00000000..0370f03b --- /dev/null +++ b/2023/practicals/reference_genome/paper_exercise/README.md @@ -0,0 +1,5 @@ +# Manual assembly +PDFs to print and cut with scissors. +Generated with [https://github.com/dib-lab/assembly-exercise](https://github.com/dib-lab/assembly-exercise) + +Actually, bruno's fork is easier to run with `python2 ./server.py` in the add-server branch of https://github.com/bmpvieira/assembly-exercise/tree/add-server diff --git a/2023/practicals/reference_genome/paper_exercise/pe_dickens.pdf b/2023/practicals/reference_genome/paper_exercise/pe_dickens.pdf new file mode 100644 index 00000000..c4dd874e Binary files /dev/null and b/2023/practicals/reference_genome/paper_exercise/pe_dickens.pdf differ diff --git a/2023/practicals/reference_genome/paper_exercise/se_long_dickens.pdf b/2023/practicals/reference_genome/paper_exercise/se_long_dickens.pdf new file mode 100644 index 00000000..621fd7d8 Binary files /dev/null and b/2023/practicals/reference_genome/paper_exercise/se_long_dickens.pdf differ diff --git a/2023/practicals/reference_genome/paper_exercise/se_small_dickens.pdf b/2023/practicals/reference_genome/paper_exercise/se_small_dickens.pdf new file mode 100644 index 00000000..6d7dc49b Binary files /dev/null and b/2023/practicals/reference_genome/paper_exercise/se_small_dickens.pdf differ diff --git a/2023/practicals/reference_genome/predictions.fa b/2023/practicals/reference_genome/predictions.fa new file mode 100644 index 00000000..e0476e77 --- /dev/null +++ b/2023/practicals/reference_genome/predictions.fa @@ -0,0 +1,4 @@ +>rice_spQ7F1X5 +MADRAPPPPPPPAGIDSRSGFCAATRIFHSTRAPGDLPPESLPMTAAAYAFSLLSSSTLPGRPALVDAATGIAISYPSFLAAVRSLAGGLWCSLGLRPGDVALVVAPSRLEVPVLDFALMSIGAVVSPANPVSTPEEYAHQVALSRPVVAFAAPEVAAKLPEHVRCVVIGSDEYGRLAASDGRRAAAPAAVAVKQSDTAAVLYSSGTTGRVKAVAITHRNLIALMSLHADNREKVAREAAEAGEEPPPPAVTLLPIPLFHVFGFMMVLRSVSMGETSVLMERFDFIAALRAIERYRVTLLPAAPPVLVAMVKYEEARRRDLSSLLVIGIGGAPLGREVAEQFASVFPNVELVQGYGLTESSGAVAATVGPEESKAYGSVGKLGSHLQAKIVDPSTGYVGDDEATAATVDSEGWLKTGDLCYFNEDGFLYIVDRLKELIKYKGYQVPPAELEHILQSHPGIADAAVIPYPDEEAGELPMAFIVRQPGSNITKEQVMDYVAKQVAPYKKVRRVAFVTAIPKSPAGKILRRELVQQALSMGASKL +>ApisMellifera_SequenceA +MLPQTPDIIPTTLNQQKCVKARALYDNIAEAPDELAFRKGDVLTVLEQNTAGLEGWWLCALRGRQGICPGNRLRLLVGQYDTGGCLVGSRPDLTISEDGIQRHGKRRSWHVQPNRVVTPQKCGDVYLYDLPASRGSPAPPSRHDSPLNSNNEHLHNSGRYTTSSRNSVDNGGDVSDCYDVPPRAIPVIPSPASSPSPAPSCYDIPRPPTSCTPISNCSGGSGVTPLDCYDVPRPLQPLTPSSSASSLTNDGSLSGSNRSSLAAPDYDVPRSRLPASSLPSRHNTPVPKTPTPPPPPQTQQIYDVPVSKELPLELDSALEGLQRLQSEASAAIARLLGFVSPVWRTPQRLDATLMDLRLAALRLRTSLHDLAEFAEGTLGNAGKAPDKGLATKLRPLVKALRDSDKLVQEAATELDAMEWDAGKLCRGGGDTPTPTNGPPSTILPPAQPDPLDQLIACARALTEDVRQVASFIQGNSTLLFKRSSIISTGSSNNSGAGEDYDYVNLDSREVVAKQREEVRASLPQELRSNYDLLVSESDNATIQMPPTTPTPMDPNDKQLLAFYAAQVITHGNHLTHAIDAFMQTVEHNQPPKVFLAHGKFVVLSAHRLVHIGDTVHRNVIRNDVKTRVLECANALNEALKQTVSKTKQAAQFFPSVSAVQEMVDSVVDVSHLAKDLKVAIINGAQQPMEVTSSNFQEVLVELDEILKNATFLCIDGEFTGLNSGPDGGVFDTPAQYYAKLRTGSMDFLLIQFGLSVFTFNKEMQKYNQRSYNFYVFPRPLNRMAPDCRFMCQTSSISFLASQGFDFNKLFKLGIPYLTTNEEEKLMKRLEEKQRIRDEGTEILPISDVERPQIEEICSRIDEFVTSETEELLIEKCNAFIRRLVYQEVKLRWPNKLKVESKMNNFGCILVVQRLGTKEEEEQREIEKREREKTEIQQAVGLSILMRKIADSGKLIVGHNMLLDLCHIVHQFFGQLPESYFEFKSLVHSLFPRILDTKIICHSQQFKENIPSSNLGILLETVSKSPFKITEVEPIDGRSYSTLSEKCHEAGYDAYITGICFIALSNYLGSLQKPEVPIVLSDSPLLNPFLNKLLIARLKDVPYINLVGDDPNPSRDHVFHLTFPKEWKFNDISHLFSPFGSVHVSWLSDISAYIELHRRDQVNEVMKVLAKTSTYKLQRYADYQASLENFNTGERKRKLSSSEETTPEAEELCGCRECAKIETETLCRA diff --git a/2023/practicals/reference_genome/pt-1-read-cleaning.md b/2023/practicals/reference_genome/pt-1-read-cleaning.md new file mode 100644 index 00000000..c21c93f9 --- /dev/null +++ b/2023/practicals/reference_genome/pt-1-read-cleaning.md @@ -0,0 +1,407 @@ +--- +layout: page +title: Part 1 - Reads to reference genome and gene predictions +post_url: pt-1-read-cleaning + +--- + +# Part 1: Reads to reference genome and gene predictions +## 1. Introduction + +[Cheap sequencing](http://www.genome.gov/sequencingcosts/) has created the opportunity to perform molecular-genetic analyses on just about anything. Traditional genetic model organisms benefit from years of efforts by expert genome assemblers, gene predictors, and curators. They have created most of the prerequisites for genomic analyses. In contrast, genomic resources are much more limited for those working on "emerging" model organisms or other species. These new organisms includes most crops, animals and plant pest species, many pathogens, and major models for ecology & evolution. + +The steps below are meant to provide some ideas that can help obtaining a reference +genome and a reference geneset of sufficient quality for many analyses. They are based on (and updated from) work we did for +the [fire ant genome](http://www.pnas.org/content/108/14/5679.long "The genome of the fire ant Solenopsis invicta")[1]. + +The dataset that you will use represents ~0.5% of the fire ant genome. This enables us to perform a toy/sandbox version of all analyses within a much shorter amount of time than would normally be required. For real projects, much more sophisticated approaches are needed! + +During this series of practicals, we will: + + 1. inspect and clean short (Illumina) reads, + 2. perform genome assembly, + 3. assess the quality of the genome assembly using simple statistics, + 4. predict protein-coding genes, + 5. assess quality of gene predictions, + 6. assess quality of the entire process using a biologically meaningful measure. + +Note: Please do not jump ahead. You will gain the most by following through each section of the practical one by one. If you're fast, dig deeper into particular aspects. Dozens of approaches and tools exist for each step - try to understand their tradeoffs. + +## 2. Software and environment setup + +### Test that the necessary bioinformatics software is available + +Run `seqtk`. If this prints `command not found`, ask for help. Otherwise, move +to the next section. If that one is available and you see it's help screen, we'll suppose that everything else is too. + +### Set up directory hierarchy to work in + +Start by creating a directory to work in. Drawing on ideas from _[Noble (2009)](http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1000424 "A Quick Guide to Organizing Computational Biology Projects")[2]_ +and others, we recommend following a specific directory convention for all your +projects. The details of the convention that we will use in this practical can +be found +[here](http://github.com/wurmlab/templates/blob/master/project_structures.md "Typical multi-day project structure"). + +For the purpose of these practicals we will use a slightly simplified version of +the directory structure explained above. + +For each practical, you will have to create the following directory structure: + +* main directory in your home directory in the format + (`YYYY-MM-DD-name_of_the_practical`, where `YYYY` is the current year, `MM` is + the current month, and `DD` is the current day, and `name_of_the_practical` + matches the practical). For instance, on the 26th of September 2023 you should + create the directory `2023-09-26_read_cleaning` for this practical. In the + tutorial we will use this example directory name. +* Inside this directory, create other three directories, called `input`, `tmp`, + and `results`. +* The directory `input` will contain the FASTQ files. +* The directory `tmp` will represent your working directory. +* The direcyory `results` will contain a copy of the final results. + +Each directory in which you have done something should include a `WHATIDID.txt` +file in which you log your commands. + +Your directory structure should look like this (run `tree` in your `home` +directory): + +```bash +2023-09-26-read_cleaning +├── input +├── tmp +├── results +└── WHATIDID.txt +``` + +Being disciplined about structuring analyses is *extremely important*. It is similar to having +a laboratory notebook. It will prevent you from becoming overwhelmed by having +too many files, or not remembering what you did where. + +## 3. Sequencing an appropriate sample + +**The properties of your data can affect the ability of bioinformatics algorithms to handle them.** +For instance, less diversity and complexity in a sample makes life easier: +assembly algorithms *really* struggle when given similar sequences. So less +heterozygosity and fewer repeats are easier. + +Thus: + +* A haploid is easier than a diploid (those of us working on haplo-diploid + Hymenoptera have it easy because male ants are haploid). +* It goes without saying that a diploid is easier than a tetraploid! +* An inbred line or strain is easier than a wild-type. +* A more compact genome (with less repetitive DNA) is easier than one full of + repeats - sorry, grasshopper & *Fritillaria* researchers! :) + +Many considerations go into the appropriate experimental design and sequencing +strategy. We will not formally cover those here & instead jump right into our data. + +## 4. Illumina short read cleaning + +In this practical, we will work with paired ends short read sequences from an Illumina machine. Each piece of DNA was thus sequenced once from the 5' and once from the 3' end. Thus we expect to have two files per sequences. + +However, sequencers aren't perfect. Several problems may affect the quality of +the reads. You can find some examples +[here](http://genomecuration.github.io/genometrain/a-experimental-design/curated-collection/Presentations/Sequencing%20Troubleshooting.pptx) +and [here](http://sequencing.qcfail.com/). Also, as you may already know, +"*garbage in – garbage out*", which means that reads should be cleaned before +performing any analysis. + +### Setup and initial inspection using FastQC + +Lets move to the main directory for this practical, so that everything we need and do and create is in one place: + +```bash +# Remember that yours may have a different date +cd ~/2023-09-26-read_cleaning +``` + +After, create a symbolic link (using `ln -s`) from the reads files to the +`input` directory: + +```bash + +# Change directory to input +cd input + +# Link the two compressed FASTQ files (remember that each correspond to one of +# the pair) +ln -s /shared/data/reads.pe1.fastq.gz . +ln -s /shared/data/reads.pe2.fastq.gz . + +# Return to the main directory +cd .. +``` + +The structure of your directory should look like this (use the command `tree`): + +```bash +2023-09-26-read_cleaning +├── input +│ ├── reads.pe1.fastq.gz -> /shared/data/reads.pe1.fastq.gz +│ └── reads.pe2.fastq.gz -> /shared/data/reads.pe2.fastq.gz +├── tmp +├── results +└── WHATIDID.txt +``` + +Now, you can start evaluating the quality of the reads `reads.pe1.fastq.gz` and +`reads.pe2.fastq.gz`. To do so, we will use +[*FastQC*](http://www.bioinformatics.babraham.ac.uk/projects/fastqc/) +([documentation](http://www.bioinformatics.babraham.ac.uk/projects/fastqc/Help/)). +FASTQC is a software tool to help visualise characteristics of a sequencing run. +It can thus inform yourread cleaning strategy. + +Run FastQC on the `reads.pe1.fastq.gz` and `reads.pe2.fastq.gz` files. +The command is given below, where instead of `YOUR_OUTDIR`, you will need +replace `YOUR_OUTDIR` with the path to your `tmp` directory (e.g. if you main +directory is `2023-09-26-read_cleaning`, you need to replace `YOUR_OUTDIR` with +`tmp`): + +```bash +fastqc --nogroup --outdir YOUR_OUTDIR input/reads.pe1.fastq.gz +fastqc --nogroup --outdir YOUR_OUTDIR input/reads.pe2.fastq.gz +``` + +The `--nogroup` option ensures that bases are not grouped together in many of +the plots generated by FastQC. This makes it easier to interpret the output in +many cases. The `--outdir` option is there to help you clearly separate input +and output files. To learn more about these options run `fastqc --help` in the +terminal. + +> **_Note:_** +> Remember to log the commands you used in the `WHATIDID.txt` file. + +Take a moment to verify your directory structure. You can do so using the `tree` +command (be aware of your current working directory using the command `pwd`): + +```bash +tree ~/2023-09-26-read_cleaning +``` + +Your [resulting directory structure](http://github.com/wurmlab/templates/blob/master/project_structures.md "Typical multi-day project structure") +(`~/2023-09-26-read_cleaning`), should look like this: + +```bash +2023-09-26-read_cleaning +├── input +│ ├── reads.pe1.fastq.gz -> /shared/data/reads.pe1.fastq.gz +│ └── reads.pe2.fastq.gz -> /shared/data/reads.pe2.fastq.gz +├── tmp +│ ├── reads.pe1_fastqc.html +│ ├── reads.pe1_fastqc.zip +│ ├── reads.pe2_fastqc.html +│ └── reads.pe2_fastqc.zip +├── results +└── WHATIDID.txt +``` + +If your directory and file structure looks different, ask for some help. + + +Now inspect the FastQC report. First, copy the files `reads.pe1_fastqc.html` and +`reads.pe2_fastqc.html` to the directory `~/www/tmp`. Then, open the browser and +go to your personal module page (e.g., if your QMUL username is `bob`, the +URL will be `https://bob.genomicscourse.com`) and click on the `~/www/tmp` link. After +that, click on one of the links corresponding to the reports files. + +> **_Question:_** +> What does the *FastQC* report tell you? +> If in doubt, check the documentation +> [here](http://www.bioinformatics.babraham.ac.uk/projects/fastqc/Help/3%20Analysis%20Modules/) +> and what the quality scores mean +> [here](https://learn.gencore.bio.nyu.edu/ngs-file-formats/quality-scores/). + +For comparison, have a look at some plots from other sequencing libraries: +e.g, [[1]](img-qc/per_base_quality.png), +[[2]](img-qc/qc_factq_tile_sequence_quality.png), +[[3]](img-qc/per_base_sequence_content.png). +*NOTE:* the results for your sequences may look different. + +Clearly, some sequences have very low quality bases towards the end. Why do you think that may be? +Furthermore, many more sequences start with the nucleotide **A** rather +than **T**. Is this what you would expect? + +> **_Question:_** +> * Which FastQC plots shows the relationship between base quality and position +> in the sequence? What else does this plot tell you about nucleotide +> composition towards the end of the sequences? +> * Should you maybe trim the sequences to remove low-quality ends? What else +> might you want to do? + +In the following sections, we will perform two cleaning steps: + +* Trimming the ends of sequence reads using cutadapt. +* K-mer filtering using *kmc3*. +* Removing sequences that are of low quality or too short using cutadapt. + +Other tools, including [*fastx_toolkit*](http://github.com/agordon/fastx_toolkit), +[*BBTools*](https://jgi.doe.gov/data-and-tools/bbtools/), and +[*Trimmomatic*](http://www.usadellab.org/cms/index.php?page=trimmomatic) can +also be useful, **but we won't use them now**. + +### Read trimming + +To clean the FASTQ sequences, we will use a software tool called +[*cutadapt*](https://cutadapt.readthedocs.io/en/stable/). As stated on the +official website: + +> Cutadapt finds and removes adapter sequences, primers, poly-A tails and +> other types of unwanted sequence from your high-throughput sequencing reads. + +Specifically, we will use `cutadapt` to trim the sequences. + +> **_Question:_** +> What is the meaning of `cutadapt` options `--cut` and `--quality-cutoff` ? +> (*Hint:* you can read a short description of the options by calling the +> command `cutadapt -h`) + +To identify relevant quality cutoffs, it is necessary to be familiar with +[base quality scores](https://learn.gencore.bio.nyu.edu/ngs-file-formats/quality-scores/) +and examine the per-base quality score in your FastQC report. + +We will run `cutadapt` with two options, `--cut` and/or `--quality-cutoff`, +corresponding to the number of nucleotides to trim from the beginning (`--cut`) +and end (`--quality-cutoff`) of the sequences. + +> **_Note:_** +> If you trim too much of your sequence (i.e., too large values for `--cut` and +> `--quality-cutoff`), you increase the likelihood of eliminating important +> information. Additionally, if the trimming is too aggressive, some sequences +> may be discarded completely, which will cause problems in the subsequent +> steps of the pre-processing. +> For this example, we suggest to keep `--cut` below 5 and `--quality-cutoff` +> below 10. + +The command to run `cutadapt` on the two reads files is reported below, where +`BEGINNING` and `CUTOFF` are the the two integer values corresponding to the +number of bases to trim from the beginning of the sequence and the quality +threshold (see the above note for suggestion about the values to use). Remember +that each `.fq` file can have a different set of values. + +```bash +cutadapt --cut BEGINNING --quality-cutoff CUTOFF input/reads.pe1.fastq.gz > tmp/reads.pe1.trimmed.fq + +cutadapt --cut BEGINNING --quality-cutoff CUTOFF input/reads.pe2.fastq.gz > tmp/reads.pe2.trimmed.fq +``` + +## 5. K-mer filtering, removal of short sequences + +Let's suppose that you have sequenced your sample at 45x genome coverage. This +means that every nucleotide of the genome was sequenced 45 times on average. +So, for a genome of 100,000,000 nucleotides, you expect to have about 4,500,000,000 +nucleotides of raw sequence. But that coverage will not be homogeneous. Instead, the real coverage distribution will be influenced by factors including DNA quality, library preparation type, how was DNA packaged within the chromosomes (e.g., hetero vs. euchromatin) and local **GC** content. But you might expect most of the genome to be covered between +20 and 70x. + +In practice, this distribution can be very strange. One way of rapidly examining +the coverage distribution before you have a reference genome is to chop your raw +sequence reads into short *"k-mers"* of *k* nucleotides long, and estimate the +frequency of occurrence of all k-mers. An example plot of k-mer frequencies from +a **haploid** sample sequenced at **~45x** coverage is shown below: + +![kmer distribution graph from UCSC](img-qc/quake_kmer_distribution.jpg) + +In the above plot, the *y* axis represents the proportion of k-mers in the +dataset that are observed *x* times (called *Coverage*). As, expected, we +observe a peak in the region close to 45, which corresponds to the targeted +coverage. + +However, we also see that a large fraction of sequences have a very low +coverage (they are found only 10 times or less). + +These rare k-mers are likely to be errors that appeared during library +preparation or sequencing, or **could be rare somatic mutations**. Analogously +(although not shown in the above plot) other k-mers may exist at very large +coverage (up to 10,000). These could be viruses or other pathogens, or highly repetitive parts of the genome, such as transposons or LINE elements. + +> **_Note_:** +> Extremely rare and extremely frequent sequences can both confuse assembly +> algorithms. Eliminating them can reduce subsequent memory, disk space and CPU +> requirements considerably. + +Below, we use [*kmc3*](http://github.com/refresh-bio/KMC) to "mask" extremely +rare k-mers (i.e., convert each base in the sequences corresponding to rare +k-mers into **N**). In this way, we will ignore these bases (those called **N**) +because they are not really present in the species. Multiple alternative +approaches for k-mer filtering exist (e.g., using +[*khmer*](http://github.com/ged-lab/khmer)). + +Here, we use *kmc3* to estimate the coverage of k-mers with a size of 21 +nucleotides. When the masked k-mers are located at the end of the reads, we trim +them in a subsequent step using *cutadapt*. If the masked k-mers are in the +**middle** of the reads, we **leave them** just masked. +Trimming reads (either masked k-mers or low quality ends in the previous step) +can cause some reads to become too short to be informative. We remove such +reads in the same step using *cutadapt*. Finally, discarding reads (because they +are too short) can cause the corresponding read of the pair to become +**"unpaired"**. While it is possible to capture and use unpaired reads, we skip +that here for simplicity. Understanding the exact commands – which are a bit +convoluted – is unnecessary. However, it is important to understand the +concept of k-mer filtering and the reasoning behind each step. + +```bash +# To mask rare k-mers we will first build a k-mer database that includes counts +# for each k-mer. +# For this, we first make a list of files to input to KMC. +ls tmp/reads.pe1.trimmed.fq tmp/reads.pe2.trimmed.fq > tmp/file_list_for_kmc + +# Build a k-mer database using k-mer size of 21 nucleotides (-k). This will +# produce two files in your tmp/ directory: 21-mers.kmc_pre and 21-mers.kmc_suf. +# The last argument (tmp) tells kmc where to put intermediate files during +# computation; these are automatically deleted afterwards. The -m option tells +# KMC to use only 4 GB of RAM. +kmc -m4 -k21 @tmp/file_list_for_kmc tmp/21-mers tmp + +# Mask k-mers (-hm) observed less than two times (-ci) in the database +# (tmp/21-mers). The -t option tells KMC to run in single-threaded mode: this is +# required to preserve the order of the reads in the file. filter is a +# sub-command of kmc_tools that has options to mask, trim, or discard reads +# contain extremely rare k-mers. +# NOTE: kmc_tools command may take a few seconds to complete and does not +# provide any visual feedback during the process. +kmc_tools -t1 filter -hm tmp/21-mers tmp/reads.pe1.trimmed.fq -ci2 tmp/reads.pe1.trimmed.norare.fq +kmc_tools -t1 filter -hm tmp/21-mers tmp/reads.pe2.trimmed.fq -ci2 tmp/reads.pe2.trimmed.norare.fq + +# Check if unpaired reads are present in the files +cutadapt -o /dev/null -p /dev/null tmp/reads.pe1.trimmed.norare.fq tmp/reads.pe2.trimmed.norare.fq + +# Trim 'N's from the ends of the reads, then discard reads shorter than 21 bp, +# and save remaining reads to the paths specified by -o and -p options. +# The -p option ensures that only paired reads are saved (an error is raised +# if unpaired reads are found). +cutadapt --trim-n --minimum-length 21 -o tmp/reads.pe1.clean.fq -p tmp/reads.pe2.clean.fq tmp/reads.pe1.trimmed.norare.fq tmp/reads.pe2.trimmed.norare.fq + +# Finally, we can copy over the cleaned reads to results directory for further analysis +cp tmp/reads.pe1.clean.fq tmp/reads.pe2.clean.fq results +``` + +### Inspecting quality of cleaned reads + +Which percentage of reads have we removed overall? (hint: `wc -l` can count +lines in a non-gzipped file). Is there a general rule about how much we should +be removing? + +## 6. References + +1. Wurm, Y., Wang, J., Riba-Grognuz, O., Corona, M., Nygaard, S., Hunt, B.G., + Ingram, K.K., Falquet, L., Nipitwattanaphon, M., Gotzek, D. and Dijkstra, + M.B., 2011. The genome of the fire ant Solenopsis invicta. *Proceedings of the 2012. + National Academy of Sciences*, 108(14), pp.5679-5684. + +2. Noble, W.S., 2009. A quick guide to organizing computational biology + projects. *PLoS computational biology*, 5(7), p.e1000424. + +## 7. Further reading + +* MARTIN Marcel. Cutadapt removes adapter sequences from high-throughput + sequencing reads. EMBnet.journal, [S.l.], v. 17, n. 1, p. pp. 10-12, may 2011. + ISSN 2226-6089. doi: https://doi.org/10.14806/ej.17.1.200. + +* Kokot, M., Długosz, M. and Deorowicz, S., 2017. KMC 3: counting and + manipulating k-mer statistics. Bioinformatics, 33(17), pp.2759-2761. + +## 8. Bonus questions if you're done early + + * Which read cleaners exist and are the most popular today? Which would you use for Illumina data? And for long-read data? Why? + * How do read cleaning strategies for RNAseq and DNAseq differ? + * Can having an existing genome assembly help with read cleaning? How? diff --git a/2023/practicals/reference_genome/pt-2-assembly.md b/2023/practicals/reference_genome/pt-2-assembly.md new file mode 100644 index 00000000..c2a678ea --- /dev/null +++ b/2023/practicals/reference_genome/pt-2-assembly.md @@ -0,0 +1,155 @@ +--- +layout: page +title: Part 2 - Genome assembly +--- + + + +# Part 2: Genome assembly + +You need to have gone through [Part 1: Read cleaning](pt-1-read-cleaning.html) +before starting this practical. + +# 1. Brief assembly example / concepts + +Many different pieces of software exist for genome assembly. We will be using +[*SPAdes*](https://cab.spbu.ru/software/spades/). + +Following the same procedure described in Section 1.2 of +[Part 1: Read cleaning](pt-1-read-cleaning.html), create a new main directory +for today's practical (e.g., `2023-09-27-assembly`), the `input`, `tmp`, +and `results` subdirectories, and the file `WHATIDID.txt` to log your +commands. +Link the output (cleaned reads) from Part 1 practical into `input` subdirectory: + +```bash +cd ~/2023-09-27-assembly +cd input +ln -s ~/2023-09-26-read_cleaning/results/reads.pe*.clean.fq . +cd .. +``` + +> **_Question:_** +> * Did you note the use of `*` in the above command? +> * What does it do? (Hint: the symbol `*` is called 'globbing') + +To assemble our cleaned reads with *SPAdes*, run the following line: +(_This will take about 10 minutes_) + +```bash +spades.py -o tmp -1 input/reads.pe1.clean.fq -2 input/reads.pe2.clean.fq +``` + +Like any other assembler, *SPAdes* creates many files, including a +`scaffolds.fasta` file that is likely to be used for follow-up +analyses. + +Copy this file to your `results` directory: + +```bash +cp tmp/scaffolds.fasta results/ +``` + +Take a look at the contents of this file (e.g., to see the first 10 lines, use +`head results/scaffolds.fasta`, or `tail results/scaffolds.fasta` to see the +last 10 lines). + +> **_Question:_** +> Does it contain a lot of **NNNN** sequences? What do you think might be the +> reason for that? (Do not worry if your assembly does not contain any **NNNN** +> sequence.) + +There are many other genome assembly approaches. While waiting for everyone to +make it to this stage, get an idea of some challenges associated to **_de novo_ +genome assembly** and the approaches used to overcome them from the following +papers: + + * [Genetic variation and the *de novo* assembly of human genomes. Chaisson et al 2015 NRG](https://www.nature.com/articles/nrg3933) + (to overcome the paywall, login via your university, or email the authors). + * The now slightly outdated (2013) [Assemblathon paper](http://gigascience.biomedcentral.com/articles/10.1186/2047-217X-2-10). + * [Metassembler: merging and optimizing *de novo* genome assemblies. Wences & Schatz (2015)](http://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0764-4). + * [A hybrid approach for *de novo* human genome sequence assembly and phasing. Mostovoy et al (2016)](https://www.nature.com/articles/nmeth.3865). + +# 2. Quality assessment + +_How do we know if our genome is good?_ + +> "... the performance of different *de novo* genome assembly algorithms can +> vary greatly on the same dataset, although it has been repeatedly demonstrated +> that no single assembler is optimal in every possible quality metric +> [6, 7, 8]. The most widely used metrics for evaluating an assembly include 1) +> contiguity statistics such as scaffold and contig N50 size, 2) accuracy +> statistics such as the number of structural errors found when compared with an +> available reference genome (GAGE (Genome Assembly Gold Standard Evaluation) +> evaluation tool [8]), 3) presence of core eukaryotic genes (CEGMA (Core +> Eukaryotic Genes Mapping Approach) [9]) or, if available, transcript mapping +> rates, and 4) the concordance of the sequence with remapped paired-end and +> mate-pair reads (REAPR (Recognizing Errors in Assemblies using Paired Reads) +> [10], assembly validation [11], or assembly likelihood [12])." - +> [Wences & Schatz (2015)](http://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0764-4) + +## 2.1 Simple metrics + +An assembly software will generally provide some statistics about what it did. +But the output formats differ between assemblers. [*Quast*](http://quast.sourceforge.net/quast), +the _Quality Assessment Tool for Genome Assemblies_ is a tool designed to +generate a standardized report. Run *Quast* on the `scaffolds.fasta` +file without special options to get the basic statistics: + +```bash +cd ~/2023-09-27-assembly/results +quast.py scaffolds.fasta +``` + +Have a look at the report (pdf or html) generated by *Quast* (copy the Quast's +output directory to `~/www/tmp` and access through your browser). + +> **_Question:_** +> * What do the values in the table mean? +> * For which values is higher better, and for which ones is smaller better? +> * Why does *Quast* use the word "contig"? + +In some cases, we have prior knowledge about the expected percentage of **GC** +content, the number of chromosomes, and the total genome size. These information +can be compared to the statistics present in Quast's report. + +## 2.2 Biologically meaningful measures + +Unfortunately, with many of the simple metrics, it is difficult to determine +whether the assembler did things correctly, or just haphazardly stuck lots of +reads together. + +We probably have other prior information about what to expect in this genome. +For example: + + 1. if we have a reference assembly from a not-too-distant relative, we can + expect that large parts of genome will be organised in the same order, i.e., + _synteny_. + 2. If we independently created a transcriptome assembly, we can expect that + the exons making each transcript will be mapped sequentially onto the + genome (see [TGNet](http://github.com/ksanao/TGNet) for an implementation). + 4. We can expect that the different scaffolds in the genome have a unimodal + distribution in sequence read coverage. Similarly, we can expect that the + percentage of **GC** content will be unimodally distributed among scaffolds. + Using this idea, the [Blobology](https://github.com/sujaikumar/assemblage) + approach determined that evidence of foreign sequences in Tardigrades is + largely due to extensive contamination rather than extensive horizontal gene + transfer [Koutsovoulos et al 2016](http://www.pnas.org/content/113/18/5053). + 5. We can expect different patterns of gene content and structure between + eukaryotes and prokaryotes. + 6. Pushing this idea further, we can expect a genome to contain a single copy + of each of the "house-keeping" genes found in related species. This is + applied in *BUSCO* (Benchmarking Universal Single-Copy Orthologs). + Note that: + * *BUSCO* is a refined, modernized implementation of [*CEGMA*]("http://korflab.ucdavis.edu/Datasets/cegma/") + (Core Eukaryotic Genes Mapping Approach). *CEGMA* examines a eukaryotic + genome assembly for presence and completeness of 248 "core eukaryotic genes". + * *Quast* also includes a "quick and dirty" method of finding genes. + +It is *very important* to understand the concepts underlying these different +approaches. + +# 3. In your own time + +Try to figure out what are the [tradeoffs between `de bruijn` graph and +`overlap-layout-consensus` assembly approaches](https://www.nature.com/articles/nrg3367). diff --git a/2023/practicals/reference_genome/pt-3-prediction.md b/2023/practicals/reference_genome/pt-3-prediction.md new file mode 100644 index 00000000..eeffe81e --- /dev/null +++ b/2023/practicals/reference_genome/pt-3-prediction.md @@ -0,0 +1,200 @@ +--- +layout: page +title: Part 3 - Gene prediction +--- + + + +# Part 3: Gene prediction + +You need to have gone through [Part 2: Genome assembly](pt-2-assembly.html) +before starting this practical. + +Many tools exist for gene prediction, some based on *ab initio* statistical +models of what a protein-coding gene should look like, others that use +similarity with protein-coding genes from other species, and others (such as +[Augustus](http://bioinf.uni-greifswald.de/augustus/) and +[SNAP](https://github.com/KorfLab/SNAP)), that use both. +There is no perfect tool or approach, thus we typically run many gene-finding +tools and call a consensus between the different predicted gene models. +[MAKER](http://www.yandell-lab.org/software/maker.html), +[BRAKER](https://github.com/Gaius-Augustus/BRAKER) and +[JAMg](https://github.com/genomecuration/JAMg) can do this for us. +In this practical, we will use `MAKER`. + +# 1. Running Maker + +Following the same procedure described in Section 1.2 of +[Part 1: Read cleaning](pt-1-read-cleaning.html), create a new main directory +for today's practical (e.g., `2023-09-29-gene_prediction`) and the `input`, +`tmp`, and `results` subdirectories, and the file `WHATIDID.txt` to log your +commands. +Link the output (assembly) from Part 2 practical into `input` subdirectory: + +```bash +cd ~/2023-09-29-gene_prediction/input +ln -s ~/2023-09-27-assembly/results/scaffolds.fasta . +cd .. +``` + +Pull out the longest few scaffolds from `scaffolds.fasta` into a new file: + +```bash +seqtk seq -L 10000 input/scaffolds.fasta > tmp/min10000.fa +``` + +Gene prediction can be difficult if the assembly is of low quality and does not +include long scaffolds. For instance, in the case of short scaffolds, if a gene +is 2,000 bp long and includes introns, it may be very hard finding many entire +genes. + +> **_Note_:** +> If you have difficulty in predicting the genes or you suspect that your +> assembly may be affected by the forementioned issues, you can use alreaady +> assembled scaffolds. +> ```bash +> # Link this scaffolds file into your input directory +> ln -s /shared/data/backup_assembly/scaffolds.fasta . +> ``` + +In this practical, we will show how to run MAKER in a simple scenario. For a +better understanding of how this tool works, and how it can be applied in real +case scenarios, we encourage to read the paper and documentation. Also, checking +which settings were used in recent publications can be very helpful. + +Change to your `tmp` directory and run `maker`: + +```bash +cd tmp +maker -OPTS +``` +This will generate an empty `maker_opts.ctl` configuration file (ignore the +warnings). Edit that file using a text editor such as `nano` or `emacs` and +specify: + + * genome: `min10000.fa` + * deactivate RepeatMasker by changing `model_org` line to `model_org=` + (i.e., nothing afer `=`) + * deactivate RepeatRunner by changing `repeat_protein` line to + `repeat_protein=` (i.e., nothing after `=`) + * Augustus_species:`honeybee1` (remember to add 1 at the end; this provides + hints to Augustus about the gene structure based on what we know about gene composition from the honeybee. + +We deactivated RepeatMakser and RepeatRunner due to computational limitations +as well as the lack of a suitable library of repetitive elements for this +species. For a real project, we *would* include RepeatMasker, likely after +creating a new repeat library for our species. +For a real project, we would also include gene expression data (RNAseq improves +gene prediction performance *tremendously*), protein sequences from related +species, and iteratively train gene prediction algorithms (e.g., Augustus and +SNAP) for our data. + +Finally, run MAKER using the edited configuration. This may take a few +minutes, depending on how much data you gave it: + +```bash +maker maker_opts.ctl +``` + +Genome annotation software like MAKER usually provide information about the +exon-intron structure of the genes (e.g., in +[GFF3 format](https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md)), +and sequence of corresponding messenger RNA and protein products (e.g., in +FASTA format). + +> **_Question:_** +> While MAKER is running, make a note of the different file formats you have +> encountered by now. +> * Which type of data do each file formats contain? +> * Do you understand the difference between the different file formats and data +> types? + +Once MAKER is done the results will be hidden in subdirectories of +`min10000.maker.output`. MAKER provides a helper script to collect this hidden +output in one place (again please ignore the warnings for these steps): + +```bash +# Pull out information about exon-intron structure of the predicted genes. This +# will be saved to the file min10000.all.gff. +gff3_merge -d min10000.maker.output/min10000_master_datastore_index.log + +# Pull out predicted messenger RNA and protein sequences. These will be saved +# to the files: min10000.all.maker.augustus.transcripts.fasta, and +# min10000.all.maker.augustus.proteins.fasta +fasta_merge -d min10000.maker.output/min10000_master_datastore_index.log +``` + +# 2. Quality control of individual genes + +So now we have some gene predictions... *how can we know if they are any good?* +The easiest way to get a feel for this is to use the following example +sequences: [predicted protein sequences from rice and honeybee](predictions.fa). +We will compare them using BLAST to known sequences from other species against the Swissprot database (faster), or the Uniref50 database (slower). + +## 2.1 Running BLAST with SequenceServer + +We will use [SequenceServer](https://sequenceserver.com) to run BLAST. Open [genomicscourse.sequenceserver.com](https://genomicscourse.sequenceserver.com) in your browser, paste the [example rice and honeybee protein sequences](predictions.fa) +in the textbox and click on the 'BLAST' button to run a BLAST search. *THIS WILL TAKE A MINUTE +OR TWO*. Alternatively, just use the results of the +[BLAST that we performed before](https://genomicscourse.sequenceserver.com/42c77718-7b26-43eb-8315-d4ee9df96985). + +> **_Question:_** +> Look at the BLAST results: +> * Do any of the gene predictions have significant similarity to known +> sequences? +> * For a given gene prediction, do you think it is complete, or can you infer +> from the BLAST alignments that something may be wrong? +> Start by comparing the length of your gene prediction to that of the BLAST +> hits. +> * Is your gene prediction considerably longer or considerably shorter than +> BLAST hits? Why? + +Now try a few of your gene predictions (**use the predicted protein +sequences**). Run BLAST on only a maximum of 12 sequences at a time (instead of +simply selecting the first 12 genes in your file, copy-paste sequences randomly +from the file). *This will take a bit longer*. + +As you can see, gene prediction software is imperfect. This is even the case +when using all available evidence. This is potentially costly for analyses that +rely on gene predictions, i.e. many of the analyses we might want to do: + +> *“Incorrect annotations [ie. gene identifications] poison every experiment +> that makes use of them. Worse still the poison spreads.”* – +> [Yandell & Ence (2012)](http://www.ncbi.nlm.nih.gov/pubmed/22510764). + +--- + +## 2.2 Using GeneValidator + +The +[*GeneValidator*](http://bioinformatics.oxfordjournals.org/content/32/10/1559.long) +tool can help to evaluate the quality of a gene prediction by comparing features +of a predicted gene to similar database sequences. This approach expects that +similar sequences should for example be of similar length. *Genevalidator* was +built to automate the comparison of sequence characteristics in a manner similar +to what we just did through visual individual BLAST results. + +Try to run the [example rice and honeybee protein sequences](predictions.fa) +through *GeneValidator*. It should be accessible at [https://genevalidator.genomicscourse.com/](https://genevalidator.genomicscourse.com/) or [https://genevalidator.wurmlab.com/](https://genevalidator.wurmlab.com/). + + +# 3. Comparing whole genesets and prioritizing genes for manual curation + +*Genevalidator*'s visual output can be handy when looking at few genes. But the +tool also provides tab-delimited output, useful when working in the command-line +or running the software on whole proteomes. This can help the analysis: + * in situations when you can choose between multiple gene sets. + * to identify which gene predictions are likely correct, and which predictions + need might require further inspection and potentially be manually fixed. + +# 4. Manual curation + +Because automated gene predictions are not perfect, manual inspection and fixing +is often required. The most commonly used software for this is +[*Apollo/WebApollo*](http://genomearchitect.org/). + +We will not curate any gene models as part of this practical, but you can learn +about it through these youtube videos: + +1. [EMBL-ABR training 20171121 - Genome Annotation using Apollo](https://youtu.be/Wec7ZlXykQc) +2. [The i5k Workspace@NAL: a pan-Arthropoda genome database](https://youtu.be/HYo2RQa4BUI?t=865) diff --git a/2023/practicals/reference_genome/soap-config b/2023/practicals/reference_genome/soap-config new file mode 100644 index 00000000..ccd8e027 --- /dev/null +++ b/2023/practicals/reference_genome/soap-config @@ -0,0 +1,8 @@ +max_rd_len=101 +[LIB] +avg_ins=355 +reverse_seq=0 +asm_flags=3 +rank=1 +q1=/data/SBCS-MSc-BioInf/user/ant.pe1.fastq +q2=/data/SBCS-MSc-BioInf/user/ant.pe2.fastq diff --git a/2023/scripts/index.md b/2023/scripts/index.md new file mode 100644 index 00000000..c038cd90 --- /dev/null +++ b/2023/scripts/index.md @@ -0,0 +1,5 @@ +--- +layout: page +--- + +{% include_relative setup.sh %} diff --git a/2023/scripts/setup.sh b/2023/scripts/setup.sh new file mode 100644 index 00000000..c5dfdcc1 --- /dev/null +++ b/2023/scripts/setup.sh @@ -0,0 +1,4 @@ +# Fix the sshfs stuff. +set -x + +cd; fusermount -u hpc; rmdir hpc \ No newline at end of file diff --git a/2023/singularity/README.md b/2023/singularity/README.md new file mode 100644 index 00000000..edfb2374 --- /dev/null +++ b/2023/singularity/README.md @@ -0,0 +1,6 @@ +Example command to build Singularity image (.simg) from a recipe file: + + sudo singularity build rstudio.simg rstudio.recipe + +You want to run the above command on prometheus. Talk to James if for +some reason the above command fails for you. diff --git a/2023/singularity/index.md b/2023/singularity/index.md new file mode 100644 index 00000000..6daa3e17 --- /dev/null +++ b/2023/singularity/index.md @@ -0,0 +1,5 @@ +--- +layout: page +--- + +{% include_relative README.md %} \ No newline at end of file diff --git a/2023/singularity/maker.recipe b/2023/singularity/maker.recipe new file mode 100644 index 00000000..98c65e30 --- /dev/null +++ b/2023/singularity/maker.recipe @@ -0,0 +1,38 @@ +Bootstrap: docker + +From: ubuntu + +%files + maker-2.31.10.tgz + +%post + # Install base packages. + apt-get update + apt-get install -y --no-install-recommends build-essential ca-certificates curl gcc-5 locales perl + + # Configure UTF8 locale. + locale-gen "en_US.UTF-8" + dpkg-reconfigure locales + + # Make gcc-5 the default. Required for SNAP. + update-alternatives --install /usr/bin/gcc gcc /usr/bin/gcc-5 10 + + # Install and configure MAKER. + tar xvf maker-2.31.10.tgz + cd maker/src + PERL_MM_USE_DEFAULT=1 perl Build.PL + echo "ynnnnn" | ./Build installdeps || : + echo "n" | ./Build installdeps + echo "n" | ./Build installexes + ./Build augustus + ./Build install + + # Clean up image + apt-get -qqy autoclean + rm -rf /var/lib/apt/lists/* /tmp/* /var/tmp/* + +%environment + export PATH=/maker/bin:$PATH + +%runscript + exec maker "$@" diff --git a/2023/singularity/rstudio.recipe b/2023/singularity/rstudio.recipe new file mode 100644 index 00000000..7ea0c1a8 --- /dev/null +++ b/2023/singularity/rstudio.recipe @@ -0,0 +1,60 @@ +# Modified from gh:NIH-HPC/singularity-examples/tree/master/rstudio + +BootStrap: docker +From: debian:buster + +%runscript + rstudio "$@" + +%post +# +# Choose your mirror from the list at +# http://cran.r-project.org/mirrors.html +# + export r_mirror="https://cran.ma.imperial.ac.uk" + +# Disable interactive package configuration prompts + export DEBIAN_FRONTEND=noninteractive + +# +# Install required Debian packages. +# + apt-get update + # libssl and libcurl are needed to build some R packages. You may + # need to install others depending on the R packages you need. + # + # libudunits2 and libgdal are needed to build adegenet. + # + # libasound is required by rstudio (other packages required by rstudio are + # automatically pulled by the commands in the Install RStudio section, + # except this one) + apt-get install -y gnupg libssl-dev libcurl4-openssl-dev libudunits2-dev \ + libgdal-dev libasound2 r-base-core r-base-dev r-recommended wget xorg + +# +# Install RStudio +# see https://www.rstudio.com/products/rstudio/download/#download +# + wget https://download1.rstudio.org/desktop/bionic/amd64/rstudio-1.2.5001-amd64.deb + dpkg -i --force-depends rstudio-1.2.5001-amd64.deb + apt-get -f install -y + +# +# Remove all downloaded packages to minimize the container size +# + rm -f rstudio-*.deb + apt-get -qqy autoclean + rm -rf /var/lib/apt/lists/* /tmp/* /var/tmp/* + + +# +# Install additional R packages from CRAN and Bioconductor +# + R --no-save --no-restore <<__INSTALLCMDS__ +packages <- c('ggplot2', 'adegenet', 'PopGenome') +install.packages(packages, repos="$r_mirror") +__INSTALLCMDS__ + +%environment +# Set locale + export LC_ALL=C.UTF-8 diff --git a/2023/singularity/sequenceserver.recipe b/2023/singularity/sequenceserver.recipe new file mode 100644 index 00000000..ac97a4e7 --- /dev/null +++ b/2023/singularity/sequenceserver.recipe @@ -0,0 +1,19 @@ +Bootstrap: docker + +# Use Debian unstable as the base so that we can get BLAST 2.9.0 from apt. +From: debian:sid + +%post + # Install base packages. + apt-get update + apt-get install -y --no-install-recommends build-essential ruby ruby-dev curl gnupg git zlib1g-dev ncbi-blast+ + + # Install sequenceserver. + gem install --pre --no-document sequenceserver + + # Clean up image + apt-get -qqy autoclean + rm -rf /var/lib/apt/lists/* /tmp/* /var/tmp/* + +%runscript + exec /usr/local/bin/sequenceserver --num_threads 8 "$@" diff --git a/2023/software.md b/2023/software.md new file mode 100644 index 00000000..595bc600 --- /dev/null +++ b/2023/software.md @@ -0,0 +1,165 @@ +# Purpose of the module + +The goal of this module is to introduce students to bioinformatics software, +without introducing any additional layer of abstraction. +All software presented here are expected to locally run on modern PCs, without the usage of High Performance Computing (HPC) environments, such as *Apocrita*. + +For this module, we will use a subset of a real-scenario dataset. Its size has been designed such that it can be processed locally. + +## PCs + +We tested the pipelines on 2019 PCs with these specifications: +* **CPU**: 4 hyper-threading cores (i.e., ability to run up to 8 threads) - the number of concurrent threads allows running **BLAST** flawslessly. +* **RAM**: 16 GB of RAM - a large amount of RAM allows a smooth experience when visualising large datasets or running browser-based apps (such as, IGV, JBrowse/WebApollo, SequenceServer). + +However, **BLAST** can still be a bit slow: comparing 2 queries to *uniref50* database (downloaded Oct, 2018) took about **3 minutes**. As this process heavily relies on hard drives capabilities, it can be speeded up by using local solid-state drives (SSD) which is now standard on mid/top-range laptops. Using an SSD should improve the performances by 3-5 folds. + +## List of software required for the practical + +**IMPORTANT**: please ensure that you are using the listed version of the software. + +The links point to the softwares official websites, where you can find their documentations and manuals. + +### General tools: +* [git](https://git-scm.com/docs/git) (GitHub) +* [htop](https://htop.dev/) (Interactive process viewer) +* [tree](http://mama.indstate.edu/users/ice/tree/) (Recursive directory listing) +* text editors: [emacs](https://www.gnu.org/software/emacs/), [vi/vim](https://www.vim.org/), [nano](https://www.nano-editor.org/), [Atom](https://atom.io/) +* [GNU parallel](https://www.gnu.org/software/parallel/) +* Latest Mozilla Firefox and Google Chrome (**set Firefox as the default browser**) +* [singularity](https://docs.sylabs.io/guides/2.6/user-guide/index.html) + +### Programming tools + +| Tool | Version | Description | +| ------- | ----------------- | -------------------------------------------------------------------------- | +| CRAN R | 3.5.2 or later | R language | +| RStudio | 1.2.5001 or later | IDE for R | +| Java | 1.8 or later | Java language (required by a few tools - some are picky about the version) | + +R packages: +* `ggplot2` +* `adegenet` +* `popgenome` + +### Bioinformatics tools: +* [FastQC](https://www.bioinformatics.babraham.ac.uk/projects/fastqc/Help/) **0.11.8** +* [seqtk](https://docs.csc.fi/apps/seqtk/) **1.3-r106** +* [kmc](https://github.com/refresh-bio/KMC) **3.0.0** +* [SOAPdenovo](https://github.com/aquaskyline/SOAPdenovo2) **2.04** +* [quast](http://quast.sourceforge.net) **5.0.2** +* [MAKER](https://www.yandell-lab.org/software/maker.html) **2.31.0** +* [SequenceServer](https://sequenceserver.com/) **2.0 beta** +* [Bowtie2](http://bowtie-bio.sourceforge.net/bowtie2/index.shtml) **2.3.5.1** +* [samtools](http://bowtie-bio.sourceforge.net/bowtie2/index.shtml) **1.9** +* [bcftools](https://samtools.github.io/bcftools/bcftools.html) **1.9** +* [bgzip](http://www.htslib.org/doc/bgzip.html) +* [IGV](https://software.broadinstitute.org/software/igv/) **Latest version** + +Additionally, for the module prior to Yannick's (this may be incomplete) +* [bwa](http://bio-bwa.sourceforge.net/) **0.7.17** +* [dotter](https://sonnhammer.sbc.su.se/Dotter.html) **4.44.1** +* [jalview](https://www.jalview.org/) **2.11.0** (requires launching with specified path to java binary) + +## Singularity images and setup + +The decision to provide singularity this year was a good one. For certain +reasons it may be desirable to use an old, highly stable linux distribution, +e.g., CentOS as the base operating system on the PC. However, this can also +complicate the installation of many software packages. Such apps can be built +and provided as a singularity image. + +Our lab created three singularity images for this year's course: maker, +sequenceserver, and rstudio. The singularity images, corresponding recipe +files, and instructions for building singularity images from recipe files +are here on Apocrita: `/data/SBCS-MSc-BioInf/2019-priyam_singularity_images`. + +A few other software were provided as singularity images this year. These were +created by Tom King and his team. + +**Singularity configuration can be improved**. All paths relevant to the practical +(e.g., `/import`) was not automatically mounted inside the image this year. This +was addressed this year by adding `-B /import:/import`) to the aliases created +for running tools inside singularity image: + +``` +alias sequenceserver="singularity run -B /import:/import sequenceserver.simg +``` + +**Singularity provides a way to configure at the system level which paths +should be automatically mounted inside the image**. This should have included +`/import` and `/run` this year (`/run` was important for rstudio). If a local +scratch is provided next year, it should be auto-mounted as well. + +Given how well Singularity interfaces with the host OS (in contrast to Docker) +it might be worth considering providing all software as a single singularity +image. + +### Gotchas + +We learnt this year the hard way that: + +* Prefer to put aliases in ~/.bashrc instead of ~/.bash_profile or the aliases + may not get sourced on certain systems. +* Check that `/tmp` is writable and all relevant paths are available inside + singularity images +* While testing the practicals pay attention to the questions that the + practical asks of the students before and after running commands. + +### Web servers + +We have not done manual curation practical for three years in a row. This has +been linked to technical challenges installing and running Afra / WebApollo. + +However, WebApollo is now very easy to use via docker on prometheus: + +``` +# Make parent directory and cd to it +mkdir 2019-10-MSc_apollo_gnG && cd $_ + +# First, make a directory called postgres which we will pass to WebApollo +mkdir postgres + +# Next, setup JBrowse. We will pass JBrowse's data directory to WebApollo. + +## Download JBrowse from https://jbrowse.org and unzip it here # + +## Install JBrowse's dependencies (all installed locally) +cd JBrowse-1.16.6 +./setup.pl + +## Copy over a genome assembly (FASTA) and annotations (GFF) to data/ ## + +## Format genome assembly. This step can take a gzip compressed file. +bin/prepare-refseqs.pl --fasta data/GCF_000188075.2_Si_gnH_genomic.fna.gz + +## Format annotations. This step cannot take a compressed file. +bin/flatfile-to-json.pl --gff data/GCF_000188075.2_Si_gnH_genomic.gff \ + --type mRNA --trackLabel RefSeqAnnotations + +## Index names - required for the search bar to work. +bin/generate-names.pl + +## Copy over BAM, BigWig and other evidence files to data/tracks/ and add them +to JBrowse using respective commands. ## + +## e.g., bam track (note that --bam_url does not begin with data/) +bin/add-bam-track.pl --label RNASeq --bam_url tracks/RNAseq_merged_subsampled.bam +## e.g., bigwig (note that --bw_url does not begin with data/) +bin/add-bw-track.pl --label RNAseq --bw_url tracks/RNAseq_merged_normalized.bw + + +# Finally, run WebApollo using Docker. This will make WebApollo instance +# accessible on port 80 on prometheus. +docker run -it -p 80:8080 -v $PWD/JBrowse-1.16.6/data:/data \ + -v $PWD/postgres:/var/lib/postgresql -e APOLLO_ADMIN_PASSWORD='compGenomics' +``` + +Upon login, first create an organism (don't use space in the name, path to data +dir in the above setup is `/data`). + +The remaining challenge of doing manual curation practical, or homework +assignment is providing 40 different problematic gene models for 40 students. +An interesting technical question is to emulate how NCBI shows RNAseq evidence +for its gene models (for e.g., search vitellogenin fire ant on NCBI and look at +the RNAseq tracks).