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calculate neighborhoods for internal nodes #71

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ajo2995 opened this issue Apr 25, 2017 · 1 comment
Open

calculate neighborhoods for internal nodes #71

ajo2995 opened this issue Apr 25, 2017 · 1 comment
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@ajo2995
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ajo2995 commented Apr 25, 2017

Since the gene tree is often displayed with many collapsed branches it would be nice to summarize the neighborhood conservation for genes in the clade.

We can walk the gene tree and assign a neighborhood to an internal node based on the (two) child nodes.

By definition, the central gene should remain in that position in the parent neighborhood. Similarly, any other pair of genes from the same gene tree in the same relative position could be assigned to the parent. The non-trivial part is dealing with local differences (genes only in one child, tandem duplications, inversions, etc.)

Lets not make it too complicated in case we are able to bring in real synteny information at a later time

@ajo2995 ajo2995 added this to the phylo milestone Apr 25, 2017
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ajo2995 commented May 3, 2017

this is an ancestral reconstruction problem

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