diff --git a/.github/workflows/release.yml b/.github/workflows/release.yml
index ac5fa1864..87b9466ba 100644
--- a/.github/workflows/release.yml
+++ b/.github/workflows/release.yml
@@ -40,6 +40,7 @@ jobs:
           push: true
           tags: |
             ghcr.io/umccr/htsget-rs:latest
+
 ## SOCI (Seekable OCI) support. Only enable when and if docker layers surpass 10MB in the future, see:
 # https://github.com/awslabs/soci-snapshotter/issues/100
 #      - name: Install aws SOCI
diff --git a/Cargo.lock b/Cargo.lock
index 4bb58e9b1..f1108cb39 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -8,7 +8,7 @@ version = "0.5.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "5f7b0a21988c1bf877cf4759ef5ddaac04c1c9fe808c9142ecb78ba97d97a28a"
 dependencies = [
- "bitflags 2.5.0",
+ "bitflags",
  "bytes",
  "futures-core",
  "futures-sink",
@@ -21,9 +21,9 @@ dependencies = [
 
 [[package]]
 name = "actix-cors"
-version = "0.6.5"
+version = "0.7.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "0346d8c1f762b41b458ed3145eea914966bb9ad20b9be0d6d463b20d45586370"
+checksum = "f9e772b3bcafe335042b5db010ab7c09013dad6eac4915c91d8d50902769f331"
 dependencies = [
  "actix-utils",
  "actix-web",
@@ -36,9 +36,9 @@ dependencies = [
 
 [[package]]
 name = "actix-http"
-version = "3.6.0"
+version = "3.7.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d223b13fd481fc0d1f83bb12659ae774d9e3601814c68a0bc539731698cca743"
+checksum = "4eb9843d84c775696c37d9a418bbb01b932629d01870722c0f13eb3f95e2536d"
 dependencies = [
  "actix-codec",
  "actix-rt",
@@ -46,8 +46,8 @@ dependencies = [
  "actix-tls",
  "actix-utils",
  "ahash",
- "base64 0.21.7",
- "bitflags 2.5.0",
+ "base64 0.22.1",
+ "bitflags",
  "brotli",
  "bytes",
  "bytestring",
@@ -55,8 +55,8 @@ dependencies = [
  "encoding_rs",
  "flate2",
  "futures-core",
- "h2",
- "http",
+ "h2 0.3.26",
+ "http 0.2.12",
  "httparse",
  "httpdate",
  "itoa",
@@ -86,13 +86,15 @@ dependencies = [
 
 [[package]]
 name = "actix-router"
-version = "0.5.2"
+version = "0.5.3"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d22475596539443685426b6bdadb926ad0ecaefdfc5fb05e5e3441f15463c511"
+checksum = "13d324164c51f63867b57e73ba5936ea151b8a41a1d23d1031eeb9f70d0236f8"
 dependencies = [
  "bytestring",
- "http",
+ "cfg-if",
+ "http 0.2.12",
  "regex",
+ "regex-lite",
  "serde",
  "tracing",
 ]
@@ -137,9 +139,9 @@ dependencies = [
 
 [[package]]
 name = "actix-tls"
-version = "3.3.0"
+version = "3.4.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d4cce60a2f2b477bc72e5cde0af1812a6e82d8fd85b5570a5dcf2a5bf2c5be5f"
+checksum = "ac453898d866cdbecdbc2334fe1738c747b4eba14a677261f2b768ba05329389"
 dependencies = [
  "actix-rt",
  "actix-service",
@@ -147,11 +149,11 @@ dependencies = [
  "futures-core",
  "impl-more",
  "pin-project-lite",
+ "rustls-pki-types",
  "tokio",
- "tokio-rustls",
+ "tokio-rustls 0.26.0",
  "tokio-util",
  "tracing",
- "webpki-roots",
 ]
 
 [[package]]
@@ -166,9 +168,9 @@ dependencies = [
 
 [[package]]
 name = "actix-web"
-version = "4.5.1"
+version = "4.6.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "43a6556ddebb638c2358714d853257ed226ece6023ef9364f23f0c70737ea984"
+checksum = "b1cf67dadb19d7c95e5a299e2dda24193b89d5d4f33a3b9800888ede9e19aa32"
 dependencies = [
  "actix-codec",
  "actix-http",
@@ -196,6 +198,7 @@ dependencies = [
  "once_cell",
  "pin-project-lite",
  "regex",
+ "regex-lite",
  "serde",
  "serde_json",
  "serde_urlencoded",
@@ -269,6 +272,12 @@ dependencies = [
  "alloc-no-stdlib",
 ]
 
+[[package]]
+name = "allocator-api2"
+version = "0.2.18"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "5c6cb57a04249c6480766f7f7cef5467412af1490f8d1e243141daddada3264f"
+
 [[package]]
 name = "android-tzdata"
 version = "0.1.1"
@@ -420,6 +429,12 @@ dependencies = [
  "bytemuck",
 ]
 
+[[package]]
+name = "atomic-waker"
+version = "1.1.2"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "1505bd5d3d116872e7271a6d4e16d81d0c8570876c8de68093a09ac269d8aac0"
+
 [[package]]
 name = "autocfg"
 version = "1.3.0"
@@ -428,75 +443,81 @@ checksum = "0c4b4d0bd25bd0b74681c0ad21497610ce1b7c91b1022cd21c80c6fbdd9476b0"
 
 [[package]]
 name = "aws-config"
-version = "0.56.1"
+version = "1.4.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "fc6b3804dca60326e07205179847f17a4fce45af3a1106939177ad41ac08a6de"
+checksum = "40ddbfb5db93d62521f47b3f223da0884a2f02741ff54cb9cda192a0e73ba08b"
 dependencies = [
  "aws-credential-types",
- "aws-http",
+ "aws-runtime",
  "aws-sdk-sso",
+ "aws-sdk-ssooidc",
  "aws-sdk-sts",
  "aws-smithy-async",
- "aws-smithy-client",
  "aws-smithy-http",
- "aws-smithy-http-tower",
  "aws-smithy-json",
+ "aws-smithy-runtime",
+ "aws-smithy-runtime-api",
  "aws-smithy-types",
  "aws-types",
  "bytes",
  "fastrand",
  "hex",
- "http",
- "hyper",
- "ring 0.16.20",
+ "http 0.2.12",
+ "hyper 0.14.28",
+ "ring",
  "time",
  "tokio",
- "tower",
  "tracing",
+ "url",
  "zeroize",
 ]
 
 [[package]]
 name = "aws-credential-types"
-version = "0.56.1"
+version = "1.2.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "70a66ac8ef5fa9cf01c2d999f39d16812e90ec1467bd382cbbb74ba23ea86201"
+checksum = "e16838e6c9e12125face1c1eff1343c75e3ff540de98ff7ebd61874a89bcfeb9"
 dependencies = [
  "aws-smithy-async",
+ "aws-smithy-runtime-api",
  "aws-smithy-types",
- "fastrand",
- "tokio",
- "tracing",
  "zeroize",
 ]
 
 [[package]]
-name = "aws-http"
-version = "0.56.1"
+name = "aws-lc-rs"
+version = "1.7.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "3e626370f9ba806ae4c439e49675fd871f5767b093075cdf4fef16cac42ba900"
+checksum = "8487b59d62764df8231cb371c459314df895b41756df457a1fb1243d65c89195"
 dependencies = [
- "aws-credential-types",
- "aws-smithy-http",
- "aws-smithy-types",
- "aws-types",
- "bytes",
- "http",
- "http-body",
- "lazy_static",
- "percent-encoding",
- "pin-project-lite",
- "tracing",
+ "aws-lc-sys",
+ "mirai-annotations",
+ "paste",
+ "zeroize",
+]
+
+[[package]]
+name = "aws-lc-sys"
+version = "0.16.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "c15eb61145320320eb919d9bab524617a7aa4216c78d342fae3a758bc33073e4"
+dependencies = [
+ "bindgen",
+ "cc",
+ "cmake",
+ "dunce",
+ "fs_extra",
+ "libc",
+ "paste",
 ]
 
 [[package]]
 name = "aws-runtime"
-version = "0.56.1"
+version = "1.2.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "07ac5cf0ff19c1bca0cea7932e11b239d1025a45696a4f44f72ea86e2b8bdd07"
+checksum = "75588e7ee5e8496eed939adac2035a6dbab9f7eb2acdd9ab2d31856dab6f3955"
 dependencies = [
  "aws-credential-types",
- "aws-http",
  "aws-sigv4",
  "aws-smithy-async",
  "aws-smithy-eventstream",
@@ -504,26 +525,28 @@ dependencies = [
  "aws-smithy-runtime-api",
  "aws-smithy-types",
  "aws-types",
+ "bytes",
  "fastrand",
- "http",
+ "http 0.2.12",
+ "http-body 0.4.6",
  "percent-encoding",
+ "pin-project-lite",
  "tracing",
  "uuid",
 ]
 
 [[package]]
 name = "aws-sdk-s3"
-version = "0.34.0"
+version = "1.29.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "42f7a233b27af6e70094eafd43d9ee11da6e78eb2c1a31e5a7de737b782c627d"
+checksum = "966646a69665bb0427460d78747204317f6639bdf5ec61305c4c5195af3dc086"
 dependencies = [
+ "ahash",
  "aws-credential-types",
- "aws-http",
  "aws-runtime",
  "aws-sigv4",
  "aws-smithy-async",
  "aws-smithy-checksums",
- "aws-smithy-client",
  "aws-smithy-eventstream",
  "aws-smithy-http",
  "aws-smithy-json",
@@ -533,27 +556,29 @@ dependencies = [
  "aws-smithy-xml",
  "aws-types",
  "bytes",
- "http",
- "http-body",
+ "fastrand",
+ "hex",
+ "hmac",
+ "http 0.2.12",
+ "http-body 0.4.6",
+ "lru",
  "once_cell",
  "percent-encoding",
- "regex",
- "tokio-stream",
+ "regex-lite",
+ "sha2",
  "tracing",
  "url",
 ]
 
 [[package]]
 name = "aws-sdk-sso"
-version = "0.30.0"
+version = "1.25.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "903f888ff190e64f6f5c83fb0f8d54f9c20481f1dc26359bb8896f5d99908949"
+checksum = "fef2d9ca2b43051224ed326ed9960a85e277b7d554a2cd0397e57c0553d86e64"
 dependencies = [
  "aws-credential-types",
- "aws-http",
  "aws-runtime",
  "aws-smithy-async",
- "aws-smithy-client",
  "aws-smithy-http",
  "aws-smithy-json",
  "aws-smithy-runtime",
@@ -561,23 +586,43 @@ dependencies = [
  "aws-smithy-types",
  "aws-types",
  "bytes",
- "http",
- "regex",
- "tokio-stream",
+ "http 0.2.12",
+ "once_cell",
+ "regex-lite",
+ "tracing",
+]
+
+[[package]]
+name = "aws-sdk-ssooidc"
+version = "1.26.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "c869d1f5c4ee7437b79c3c1664ddbf7a60231e893960cf82b2b299a5ccf2cc5d"
+dependencies = [
+ "aws-credential-types",
+ "aws-runtime",
+ "aws-smithy-async",
+ "aws-smithy-http",
+ "aws-smithy-json",
+ "aws-smithy-runtime",
+ "aws-smithy-runtime-api",
+ "aws-smithy-types",
+ "aws-types",
+ "bytes",
+ "http 0.2.12",
+ "once_cell",
+ "regex-lite",
  "tracing",
 ]
 
 [[package]]
 name = "aws-sdk-sts"
-version = "0.30.0"
+version = "1.25.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "a47ad6bf01afc00423d781d464220bf69fb6a674ad6629cbbcb06d88cdc2be82"
+checksum = "9e2b4a632a59e4fab7abf1db0d94a3136ad7871aba46bebd1fdb95c7054afcdb"
 dependencies = [
  "aws-credential-types",
- "aws-http",
  "aws-runtime",
  "aws-smithy-async",
- "aws-smithy-client",
  "aws-smithy-http",
  "aws-smithy-json",
  "aws-smithy-query",
@@ -586,49 +631,57 @@ dependencies = [
  "aws-smithy-types",
  "aws-smithy-xml",
  "aws-types",
- "http",
- "regex",
+ "http 0.2.12",
+ "once_cell",
+ "regex-lite",
  "tracing",
 ]
 
 [[package]]
 name = "aws-sigv4"
-version = "0.56.1"
+version = "1.2.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "b7b28f4910bb956b7ab320b62e98096402354eca976c587d1eeccd523d9bac03"
+checksum = "58b56f1cbe6fd4d0c2573df72868f20ab1c125ca9c9dbce17927a463433a2e57"
 dependencies = [
+ "aws-credential-types",
  "aws-smithy-eventstream",
  "aws-smithy-http",
+ "aws-smithy-runtime-api",
+ "aws-smithy-types",
  "bytes",
+ "crypto-bigint 0.5.5",
  "form_urlencoded",
  "hex",
  "hmac",
- "http",
+ "http 0.2.12",
+ "http 1.1.0",
  "once_cell",
+ "p256",
  "percent-encoding",
- "regex",
+ "ring",
  "sha2",
+ "subtle",
  "time",
  "tracing",
+ "zeroize",
 ]
 
 [[package]]
 name = "aws-smithy-async"
-version = "0.56.1"
+version = "1.2.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "2cdb73f85528b9d19c23a496034ac53703955a59323d581c06aa27b4e4e247af"
+checksum = "62220bc6e97f946ddd51b5f1361f78996e704677afc518a4ff66b7a72ea1378c"
 dependencies = [
  "futures-util",
  "pin-project-lite",
  "tokio",
- "tokio-stream",
 ]
 
 [[package]]
 name = "aws-smithy-checksums"
-version = "0.56.1"
+version = "0.60.7"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "afb15946af1b8d3beeff53ad991d9bff68ac22426b6d40372b958a75fa61eaed"
+checksum = "83fa43bc04a6b2441968faeab56e68da3812f978a670a5db32accbdcafddd12f"
 dependencies = [
  "aws-smithy-http",
  "aws-smithy-types",
@@ -636,8 +689,8 @@ dependencies = [
  "crc32c",
  "crc32fast",
  "hex",
- "http",
- "http-body",
+ "http 0.2.12",
+ "http-body 0.4.6",
  "md-5",
  "pin-project-lite",
  "sha1",
@@ -645,35 +698,11 @@ dependencies = [
  "tracing",
 ]
 
-[[package]]
-name = "aws-smithy-client"
-version = "0.56.1"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "c27b2756264c82f830a91cb4d2d485b2d19ad5bea476d9a966e03d27f27ba59a"
-dependencies = [
- "aws-smithy-async",
- "aws-smithy-http",
- "aws-smithy-http-tower",
- "aws-smithy-types",
- "bytes",
- "fastrand",
- "http",
- "http-body",
- "hyper",
- "hyper-rustls",
- "lazy_static",
- "pin-project-lite",
- "rustls",
- "tokio",
- "tower",
- "tracing",
-]
-
 [[package]]
 name = "aws-smithy-eventstream"
-version = "0.56.1"
+version = "0.60.4"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "850233feab37b591b7377fd52063aa37af615687f5896807abe7f49bd4e1d25b"
+checksum = "e6363078f927f612b970edf9d1903ef5cef9a64d1e8423525ebb1f0a1633c858"
 dependencies = [
  "aws-smithy-types",
  "bytes",
@@ -682,62 +711,45 @@ dependencies = [
 
 [[package]]
 name = "aws-smithy-http"
-version = "0.56.1"
+version = "0.60.8"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "54cdcf365d8eee60686885f750a34c190e513677db58bbc466c44c588abf4199"
+checksum = "4a7de001a1b9a25601016d8057ea16e31a45fdca3751304c8edf4ad72e706c08"
 dependencies = [
  "aws-smithy-eventstream",
+ "aws-smithy-runtime-api",
  "aws-smithy-types",
  "bytes",
  "bytes-utils",
  "futures-core",
- "http",
- "http-body",
- "hyper",
+ "http 0.2.12",
+ "http-body 0.4.6",
  "once_cell",
  "percent-encoding",
  "pin-project-lite",
  "pin-utils",
- "tokio",
- "tokio-util",
- "tracing",
-]
-
-[[package]]
-name = "aws-smithy-http-tower"
-version = "0.56.1"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "822de399d0ce62829a69dfa8c5cd08efdbe61a7426b953e2268f8b8b52a607bd"
-dependencies = [
- "aws-smithy-http",
- "aws-smithy-types",
- "bytes",
- "http",
- "http-body",
- "pin-project-lite",
- "tower",
  "tracing",
 ]
 
 [[package]]
 name = "aws-smithy-json"
-version = "0.56.1"
+version = "0.60.7"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "4fb1e7ab8fa7ad10c193af7ae56d2420989e9f4758bf03601a342573333ea34f"
+checksum = "4683df9469ef09468dad3473d129960119a0d3593617542b7d52086c8486f2d6"
 dependencies = [
  "aws-smithy-types",
 ]
 
 [[package]]
 name = "aws-smithy-protocol-test"
-version = "0.56.1"
+version = "0.60.7"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "30600c65e5a9bedccff93c75872731ddc8a38dafbf95a18ba752227ab04f8574"
+checksum = "a31e8279cb24640c7349f2bda6ca818d5fcc85129386bd73c1d0999430d6ddf2"
 dependencies = [
  "assert-json-diff",
- "http",
+ "aws-smithy-runtime-api",
+ "http 0.2.12",
  "pretty_assertions",
- "regex",
+ "regex-lite",
  "roxmltree",
  "serde_json",
  "thiserror",
@@ -745,9 +757,9 @@ dependencies = [
 
 [[package]]
 name = "aws-smithy-query"
-version = "0.56.1"
+version = "0.60.7"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "28556a3902091c1f768a34f6c998028921bdab8d47d92586f363f14a4a32d047"
+checksum = "f2fbd61ceb3fe8a1cb7352e42689cec5335833cd9f94103a61e98f9bb61c64bb"
 dependencies = [
  "aws-smithy-types",
  "urlencoding",
@@ -755,23 +767,30 @@ dependencies = [
 
 [[package]]
 name = "aws-smithy-runtime"
-version = "0.56.1"
+version = "1.5.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "745e096b3553e7e0f40622aa04971ce52765af82bebdeeac53aa6fc82fe801e6"
+checksum = "c9ac79e9f3a4d576f3cd4a470a0275b138d9e7b11b1cd514a6858ae0a79dd5bb"
 dependencies = [
  "aws-smithy-async",
- "aws-smithy-client",
  "aws-smithy-http",
  "aws-smithy-protocol-test",
  "aws-smithy-runtime-api",
  "aws-smithy-types",
  "bytes",
  "fastrand",
- "http",
- "http-body",
+ "h2 0.3.26",
+ "http 0.2.12",
+ "http-body 0.4.6",
+ "http-body 1.0.0",
+ "hyper 0.14.28",
+ "hyper-rustls 0.24.2",
+ "indexmap 2.2.6",
  "once_cell",
  "pin-project-lite",
  "pin-utils",
+ "rustls 0.21.12",
+ "serde",
+ "serde_json",
  "tokio",
  "tracing",
  "tracing-subscriber",
@@ -779,38 +798,52 @@ dependencies = [
 
 [[package]]
 name = "aws-smithy-runtime-api"
-version = "0.56.1"
+version = "1.6.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "93d0ae0c9cfd57944e9711ea610b48a963fb174a53aabacc08c5794a594b1d02"
+checksum = "04ec42c2f5c0e7796a2848dde4d9f3bf8ce12ccbb3d5aa40c52fa0cdd61a1c47"
 dependencies = [
  "aws-smithy-async",
- "aws-smithy-http",
  "aws-smithy-types",
  "bytes",
- "http",
+ "http 0.2.12",
+ "http 1.1.0",
+ "pin-project-lite",
  "tokio",
  "tracing",
+ "zeroize",
 ]
 
 [[package]]
 name = "aws-smithy-types"
-version = "0.56.1"
+version = "1.1.9"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d90dbc8da2f6be461fa3c1906b20af8f79d14968fe47f2b7d29d086f62a51728"
+checksum = "baf98d97bba6ddaba180f1b1147e202d8fe04940403a95a3f826c790f931bbd1"
 dependencies = [
  "base64-simd",
+ "bytes",
+ "bytes-utils",
+ "futures-core",
+ "http 0.2.12",
+ "http 1.1.0",
+ "http-body 0.4.6",
+ "http-body 1.0.0",
+ "http-body-util",
  "itoa",
  "num-integer",
+ "pin-project-lite",
+ "pin-utils",
  "ryu",
  "serde",
  "time",
+ "tokio",
+ "tokio-util",
 ]
 
 [[package]]
 name = "aws-smithy-types-convert"
-version = "0.56.1"
+version = "0.60.8"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "4aec73ec67166b7bc64804aba0cf38808f5b2aecf05d353cad2e855aabce431a"
+checksum = "7f280f434214856abace637b1f944d50ccca216814813acd195cdd7f206ce17f"
 dependencies = [
  "aws-smithy-types",
  "time",
@@ -818,39 +851,38 @@ dependencies = [
 
 [[package]]
 name = "aws-smithy-xml"
-version = "0.56.1"
+version = "0.60.8"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "e01d2dedcdd8023043716cfeeb3c6c59f2d447fce365d8e194838891794b23b6"
+checksum = "d123fbc2a4adc3c301652ba8e149bf4bc1d1725affb9784eb20c953ace06bf55"
 dependencies = [
  "xmlparser",
 ]
 
 [[package]]
 name = "aws-types"
-version = "0.56.1"
+version = "1.2.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "85aa0451bf8af1bf22a4f028d5d28054507a14be43cb8ac0597a8471fba9edfe"
+checksum = "a807d90cd50a969b3d95e4e7ad1491fcae13c6e83948d8728363ecc09d66343a"
 dependencies = [
  "aws-credential-types",
  "aws-smithy-async",
- "aws-smithy-client",
- "aws-smithy-http",
+ "aws-smithy-runtime-api",
  "aws-smithy-types",
- "http",
+ "http 0.2.12",
  "rustc_version",
  "tracing",
 ]
 
 [[package]]
 name = "aws_lambda_events"
-version = "0.12.1"
+version = "0.15.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "03611508dd1e514e311caec235b581c99a4cb66fa1771bd502819eed69894f12"
+checksum = "7319a086b79c3ff026a33a61e80f04fd3885fbb73237981ea080d21944e1cb1c"
 dependencies = [
- "base64 0.21.7",
+ "base64 0.22.1",
  "bytes",
- "http",
- "http-body",
+ "http 1.1.0",
+ "http-body 1.0.0",
  "http-serde",
  "query_map",
  "serde",
@@ -859,18 +891,19 @@ dependencies = [
 
 [[package]]
 name = "axum"
-version = "0.6.20"
+version = "0.7.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "3b829e4e32b91e643de6eafe82b1d90675f5874230191a4ffbc1b336dec4d6bf"
+checksum = "3a6c9af12842a67734c9a2e355436e5d03b22383ed60cf13cd0c18fbfe3dcbcf"
 dependencies = [
  "async-trait",
  "axum-core",
- "bitflags 1.3.2",
  "bytes",
  "futures-util",
- "http",
- "http-body",
- "hyper",
+ "http 1.1.0",
+ "http-body 1.0.0",
+ "http-body-util",
+ "hyper 1.3.1",
+ "hyper-util",
  "itoa",
  "matchit",
  "memchr",
@@ -882,28 +915,33 @@ dependencies = [
  "serde_json",
  "serde_path_to_error",
  "serde_urlencoded",
- "sync_wrapper",
+ "sync_wrapper 1.0.1",
  "tokio",
  "tower",
  "tower-layer",
  "tower-service",
+ "tracing",
 ]
 
 [[package]]
 name = "axum-core"
-version = "0.3.4"
+version = "0.4.3"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "759fa577a247914fd3f7f76d62972792636412fbfd634cd452f6a385a74d2d2c"
+checksum = "a15c63fd72d41492dc4f497196f5da1fb04fb7529e631d73630d1b491e47a2e3"
 dependencies = [
  "async-trait",
  "bytes",
  "futures-util",
- "http",
- "http-body",
+ "http 1.1.0",
+ "http-body 1.0.0",
+ "http-body-util",
  "mime",
+ "pin-project-lite",
  "rustversion",
+ "sync_wrapper 0.1.2",
  "tower-layer",
  "tower-service",
+ "tracing",
 ]
 
 [[package]]
@@ -922,10 +960,10 @@ dependencies = [
 ]
 
 [[package]]
-name = "base64"
-version = "0.20.0"
+name = "base16ct"
+version = "0.1.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "0ea22880d78093b0cbe17c89f64a7d457941e65759157ec6cb31a31d652b05e5"
+checksum = "349a06037c7bf932dd7e7d1f653678b2038b9ad46a74102f1fc7bd7872678cce"
 
 [[package]]
 name = "base64"
@@ -950,16 +988,39 @@ dependencies = [
 ]
 
 [[package]]
-name = "bit-vec"
-version = "0.6.3"
+name = "base64ct"
+version = "1.6.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "349f9b6a179ed607305526ca489b34ad0a41aed5f7980fa90eb03160b69598fb"
+checksum = "8c3c1a368f70d6cf7302d78f8f7093da241fb8e8807c05cc9e51a125895a6d5b"
 
 [[package]]
-name = "bitflags"
-version = "1.3.2"
+name = "bindgen"
+version = "0.69.4"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "a00dc851838a2120612785d195287475a3ac45514741da670b735818822129a0"
+dependencies = [
+ "bitflags",
+ "cexpr",
+ "clang-sys",
+ "itertools",
+ "lazy_static",
+ "lazycell",
+ "log",
+ "prettyplease",
+ "proc-macro2",
+ "quote",
+ "regex",
+ "rustc-hash",
+ "shlex",
+ "syn 2.0.61",
+ "which",
+]
+
+[[package]]
+name = "bit-vec"
+version = "0.6.3"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "bef38d45163c2f1dde094a7dfd33ccf595c92905c8f8f4fdc18d06fb1037718a"
+checksum = "349f9b6a179ed607305526ca489b34ad0a41aed5f7980fa90eb03160b69598fb"
 
 [[package]]
 name = "bitflags"
@@ -978,9 +1039,9 @@ dependencies = [
 
 [[package]]
 name = "brotli"
-version = "3.5.0"
+version = "6.0.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d640d25bc63c50fb1f0b545ffd80207d2e10a4c965530809b40ba3386825c391"
+checksum = "74f7971dbd9326d58187408ab83117d8ac1bb9c17b085fdacd1cf2f598719b6b"
 dependencies = [
  "alloc-no-stdlib",
  "alloc-stdlib",
@@ -989,9 +1050,9 @@ dependencies = [
 
 [[package]]
 name = "brotli-decompressor"
-version = "2.5.1"
+version = "4.0.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "4e2e4afe60d7dd600fdd3de8d0f08c2b7ec039712e3b6137ff98b7004e82de4f"
+checksum = "e6221fe77a248b9117d431ad93761222e1cf8ff282d9d1d5d9f53d6299a1cf76"
 dependencies = [
  "alloc-no-stdlib",
  "alloc-stdlib",
@@ -1091,6 +1152,15 @@ dependencies = [
  "once_cell",
 ]
 
+[[package]]
+name = "cexpr"
+version = "0.6.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "6fac387a98bb7c37292057cffc56d62ecb629900026402633ae9160df93a8766"
+dependencies = [
+ "nom",
+]
+
 [[package]]
 name = "cfg-if"
 version = "1.0.0"
@@ -1137,6 +1207,17 @@ dependencies = [
  "half",
 ]
 
+[[package]]
+name = "clang-sys"
+version = "1.7.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "67523a3b4be3ce1989d607a828d036249522dd9c1c8de7f4dd2dae43a37369d1"
+dependencies = [
+ "glob",
+ "libc",
+ "libloading",
+]
+
 [[package]]
 name = "clap"
 version = "4.5.4"
@@ -1177,12 +1258,27 @@ version = "0.7.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "98cc8fbded0c607b7ba9dd60cd98df59af97e84d24e49c8557331cfc26d301ce"
 
+[[package]]
+name = "cmake"
+version = "0.1.50"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "a31c789563b815f77f4250caee12365734369f942439b7defd71e18a48197130"
+dependencies = [
+ "cc",
+]
+
 [[package]]
 name = "colorchoice"
 version = "1.0.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "0b6a852b24ab71dffc585bcb46eaf7959d175cb865a7152e35b348d1b2960422"
 
+[[package]]
+name = "const-oid"
+version = "0.9.6"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "c2459377285ad874054d797f3ccebf984978aa39129f6eafde5cdc8315b612f8"
+
 [[package]]
 name = "convert_case"
 version = "0.4.0"
@@ -1321,6 +1417,28 @@ version = "0.2.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "7a81dae078cea95a014a339291cec439d2f232ebe854a9d672b796c6afafa9b7"
 
+[[package]]
+name = "crypto-bigint"
+version = "0.4.9"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "ef2b4b23cddf68b89b8f8069890e8c270d54e2d5fe1b143820234805e4cb17ef"
+dependencies = [
+ "generic-array",
+ "rand_core",
+ "subtle",
+ "zeroize",
+]
+
+[[package]]
+name = "crypto-bigint"
+version = "0.5.5"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "0dc92fb57ca44df6db8059111ab3af99a63d5d0f8375d9972e319a379c6bab76"
+dependencies = [
+ "rand_core",
+ "subtle",
+]
+
 [[package]]
 name = "crypto-common"
 version = "0.1.6"
@@ -1372,6 +1490,16 @@ version = "0.3.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "5c297a1c74b71ae29df00c3e22dd9534821d60eb9af5a0192823fa2acea70c2a"
 
+[[package]]
+name = "der"
+version = "0.6.1"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "f1a467a65c5e759bce6e65eaf91cc29f466cdc57cb65777bd646872a8a1fd4de"
+dependencies = [
+ "const-oid",
+ "zeroize",
+]
+
 [[package]]
 name = "deranged"
 version = "0.3.11"
@@ -1412,12 +1540,50 @@ dependencies = [
  "subtle",
 ]
 
+[[package]]
+name = "dunce"
+version = "1.0.4"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "56ce8c6da7551ec6c462cbaf3bfbc75131ebbfa1c944aeaa9dab51ca1c5f0c3b"
+
+[[package]]
+name = "ecdsa"
+version = "0.14.8"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "413301934810f597c1d19ca71c8710e99a3f1ba28a0d2ebc01551a2daeea3c5c"
+dependencies = [
+ "der",
+ "elliptic-curve",
+ "rfc6979",
+ "signature",
+]
+
 [[package]]
 name = "either"
 version = "1.11.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "a47c1c47d2f5964e29c61246e81db715514cd532db6b5116a25ea3c03d6780a2"
 
+[[package]]
+name = "elliptic-curve"
+version = "0.12.3"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "e7bb888ab5300a19b8e5bceef25ac745ad065f3c9f7efc6de1b91958110891d3"
+dependencies = [
+ "base16ct",
+ "crypto-bigint 0.4.9",
+ "der",
+ "digest",
+ "ff",
+ "generic-array",
+ "group",
+ "pkcs8",
+ "rand_core",
+ "sec1",
+ "subtle",
+ "zeroize",
+]
+
 [[package]]
 name = "encoding_rs"
 version = "0.8.34"
@@ -1461,6 +1627,16 @@ version = "2.1.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "9fc0510504f03c51ada170672ac806f1f105a88aa97a5281117e1ddc3368e51a"
 
+[[package]]
+name = "ff"
+version = "0.12.1"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "d013fc25338cc558c5c2cfbad646908fb23591e2404481826742b651c9af7160"
+dependencies = [
+ "rand_core",
+ "subtle",
+]
+
 [[package]]
 name = "figment"
 version = "0.10.18"
@@ -1502,6 +1678,12 @@ dependencies = [
  "percent-encoding",
 ]
 
+[[package]]
+name = "fs_extra"
+version = "1.3.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "42703706b716c37f96a77aea830392ad231f44c9e9a67872fa5548707e11b11c"
+
 [[package]]
 name = "futures"
 version = "0.3.30"
@@ -1618,6 +1800,23 @@ version = "0.28.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "4271d37baee1b8c7e4b708028c57d816cf9d2434acb33a549475f78c181f6253"
 
+[[package]]
+name = "glob"
+version = "0.3.1"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "d2fabcfbdc87f4758337ca535fb41a6d701b65693ce38287d856d1674551ec9b"
+
+[[package]]
+name = "group"
+version = "0.12.1"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "5dfbfb3a6cfbd390d5c9564ab283a0349b9b9fcd46a706c1eb10e0db70bfbac7"
+dependencies = [
+ "ff",
+ "rand_core",
+ "subtle",
+]
+
 [[package]]
 name = "h2"
 version = "0.3.26"
@@ -1629,7 +1828,26 @@ dependencies = [
  "futures-core",
  "futures-sink",
  "futures-util",
- "http",
+ "http 0.2.12",
+ "indexmap 2.2.6",
+ "slab",
+ "tokio",
+ "tokio-util",
+ "tracing",
+]
+
+[[package]]
+name = "h2"
+version = "0.4.5"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "fa82e28a107a8cc405f0839610bdc9b15f1e25ec7d696aa5cf173edbcb1486ab"
+dependencies = [
+ "atomic-waker",
+ "bytes",
+ "fnv",
+ "futures-core",
+ "futures-sink",
+ "http 1.1.0",
  "indexmap 2.2.6",
  "slab",
  "tokio",
@@ -1658,6 +1876,10 @@ name = "hashbrown"
 version = "0.14.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "e5274423e17b7c9fc20b6e7e208532f9b19825d82dfd615708b70edd83df41f1"
+dependencies = [
+ "ahash",
+ "allocator-api2",
+]
 
 [[package]]
 name = "heck"
@@ -1696,6 +1918,15 @@ dependencies = [
  "digest",
 ]
 
+[[package]]
+name = "home"
+version = "0.5.9"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "e3d1354bf6b7235cb4a0576c2619fd4ed18183f689b12b006a0ee7329eeff9a5"
+dependencies = [
+ "windows-sys 0.52.0",
+]
+
 [[package]]
 name = "htsget-actix"
 version = "0.6.0"
@@ -1710,9 +1941,10 @@ dependencies = [
  "htsget-http",
  "htsget-search",
  "htsget-test",
- "http",
+ "http 0.2.12",
+ "http 1.1.0",
  "reqwest",
- "rustls-pemfile",
+ "rustls-pemfile 2.1.2",
  "serde",
  "serde_json",
  "tempfile",
@@ -1728,14 +1960,15 @@ dependencies = [
  "async-trait",
  "clap",
  "figment",
- "http",
+ "http 1.1.0",
  "http-serde",
  "noodles",
  "rcgen",
  "regex",
  "reqwest",
- "rustls",
- "rustls-pemfile",
+ "rustls 0.23.7",
+ "rustls-pemfile 2.1.2",
+ "rustls-pki-types",
  "serde",
  "serde_json",
  "serde_regex",
@@ -1756,7 +1989,7 @@ dependencies = [
  "htsget-config",
  "htsget-search",
  "htsget-test",
- "http",
+ "http 1.1.0",
  "serde",
  "thiserror",
  "tokio",
@@ -1795,7 +2028,7 @@ dependencies = [
  "aws-config",
  "aws-sdk-s3",
  "axum",
- "base64 0.21.7",
+ "base64 0.22.1",
  "bytes",
  "criterion",
  "data-url",
@@ -1803,17 +2036,18 @@ dependencies = [
  "futures-util",
  "htsget-config",
  "htsget-test",
- "http",
- "hyper",
+ "http 1.1.0",
+ "hyper 1.3.1",
+ "hyper-util",
  "noodles",
  "pin-project-lite",
  "reqwest",
- "rustls-pemfile",
+ "rustls-pemfile 2.1.2",
  "serde",
  "tempfile",
  "thiserror",
  "tokio",
- "tokio-rustls",
+ "tokio-rustls 0.26.0",
  "tokio-util",
  "tower",
  "tower-http",
@@ -1829,10 +2063,10 @@ dependencies = [
  "aws-config",
  "aws-credential-types",
  "aws-sdk-s3",
- "base64 0.21.7",
+ "base64 0.22.1",
  "futures",
  "htsget-config",
- "http",
+ "http 1.1.0",
  "mime",
  "noodles",
  "rcgen",
@@ -1858,6 +2092,17 @@ dependencies = [
  "itoa",
 ]
 
+[[package]]
+name = "http"
+version = "1.1.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "21b9ddb458710bc376481b842f5da65cdf31522de232c1ca8146abce2a358258"
+dependencies = [
+ "bytes",
+ "fnv",
+ "itoa",
+]
+
 [[package]]
 name = "http-body"
 version = "0.4.6"
@@ -1865,23 +2110,46 @@ source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "7ceab25649e9960c0311ea418d17bee82c0dcec1bd053b5f9a66e265a693bed2"
 dependencies = [
  "bytes",
- "http",
+ "http 0.2.12",
+ "pin-project-lite",
+]
+
+[[package]]
+name = "http-body"
+version = "1.0.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "1cac85db508abc24a2e48553ba12a996e87244a0395ce011e62b37158745d643"
+dependencies = [
+ "bytes",
+ "http 1.1.0",
+]
+
+[[package]]
+name = "http-body-util"
+version = "0.1.1"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "0475f8b2ac86659c21b64320d5d653f9efe42acd2a4e560073ec61a155a34f1d"
+dependencies = [
+ "bytes",
+ "futures-core",
+ "http 1.1.0",
+ "http-body 1.0.0",
  "pin-project-lite",
 ]
 
 [[package]]
 name = "http-range-header"
-version = "0.3.1"
+version = "0.4.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "add0ab9360ddbd88cfeb3bd9574a1d85cfdfa14db10b3e21d3700dbc4328758f"
+checksum = "08a397c49fec283e3d6211adbe480be95aae5f304cfb923e9970e08956d5168a"
 
 [[package]]
 name = "http-serde"
-version = "1.1.3"
+version = "2.1.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "6f560b665ad9f1572cfcaf034f7fb84338a7ce945216d64a90fd81f046a3caee"
+checksum = "1133cafcce27ea69d35e56b3a8772e265633e04de73c5f4e1afdffc1d19b5419"
 dependencies = [
- "http",
+ "http 1.1.0",
  "serde",
 ]
 
@@ -1899,25 +2167,46 @@ checksum = "df3b46402a9d5adb4c86a0cf463f42e19994e3ee891101b1841f30a545cb49a9"
 
 [[package]]
 name = "hyper"
-version = "0.14.28"
+version = "0.14.28"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "bf96e135eb83a2a8ddf766e426a841d8ddd7449d5f00d34ea02b41d2f19eef80"
+dependencies = [
+ "bytes",
+ "futures-channel",
+ "futures-core",
+ "futures-util",
+ "h2 0.3.26",
+ "http 0.2.12",
+ "http-body 0.4.6",
+ "httparse",
+ "httpdate",
+ "itoa",
+ "pin-project-lite",
+ "socket2",
+ "tokio",
+ "tower-service",
+ "tracing",
+ "want",
+]
+
+[[package]]
+name = "hyper"
+version = "1.3.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "bf96e135eb83a2a8ddf766e426a841d8ddd7449d5f00d34ea02b41d2f19eef80"
+checksum = "fe575dd17d0862a9a33781c8c4696a55c320909004a67a00fb286ba8b1bc496d"
 dependencies = [
  "bytes",
  "futures-channel",
- "futures-core",
  "futures-util",
- "h2",
- "http",
- "http-body",
+ "h2 0.4.5",
+ "http 1.1.0",
+ "http-body 1.0.0",
  "httparse",
  "httpdate",
  "itoa",
  "pin-project-lite",
- "socket2",
+ "smallvec",
  "tokio",
- "tower-service",
- "tracing",
  "want",
 ]
 
@@ -1928,13 +2217,50 @@ source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "ec3efd23720e2049821a693cbc7e65ea87c72f1c58ff2f9522ff332b1491e590"
 dependencies = [
  "futures-util",
- "http",
- "hyper",
+ "http 0.2.12",
+ "hyper 0.14.28",
  "log",
- "rustls",
+ "rustls 0.21.12",
  "rustls-native-certs",
  "tokio",
- "tokio-rustls",
+ "tokio-rustls 0.24.1",
+]
+
+[[package]]
+name = "hyper-rustls"
+version = "0.26.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "a0bea761b46ae2b24eb4aef630d8d1c398157b6fc29e6350ecf090a0b70c952c"
+dependencies = [
+ "futures-util",
+ "http 1.1.0",
+ "hyper 1.3.1",
+ "hyper-util",
+ "rustls 0.22.4",
+ "rustls-pki-types",
+ "tokio",
+ "tokio-rustls 0.25.0",
+ "tower-service",
+]
+
+[[package]]
+name = "hyper-util"
+version = "0.1.3"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "ca38ef113da30126bbff9cd1705f9273e15d45498615d138b0c20279ac7a76aa"
+dependencies = [
+ "bytes",
+ "futures-channel",
+ "futures-util",
+ "http 1.1.0",
+ "http-body 1.0.0",
+ "hyper 1.3.1",
+ "pin-project-lite",
+ "socket2",
+ "tokio",
+ "tower",
+ "tower-service",
+ "tracing",
 ]
 
 [[package]]
@@ -2068,21 +2394,24 @@ dependencies = [
 
 [[package]]
 name = "lambda_http"
-version = "0.8.3"
+version = "0.11.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "2505c4a24f5a8d8ac66a87691215ec1f79736c5bc6e62bb921788dca9753f650"
+checksum = "5ebde9aedfdf8c2bac4365d9adafae6ca6d631b0ea221734ac802595fcd141cb"
 dependencies = [
  "aws_lambda_events",
  "base64 0.21.7",
  "bytes",
  "encoding_rs",
  "futures",
- "http",
- "http-body",
- "hyper",
+ "futures-util",
+ "http 1.1.0",
+ "http-body 1.0.0",
+ "http-body-util",
+ "hyper 1.3.1",
  "lambda_runtime",
  "mime",
  "percent-encoding",
+ "pin-project-lite",
  "serde",
  "serde_json",
  "serde_urlencoded",
@@ -2092,38 +2421,51 @@ dependencies = [
 
 [[package]]
 name = "lambda_runtime"
-version = "0.8.3"
+version = "0.11.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "deca8f65d7ce9a8bfddebb49d7d91b22e788a59ca0c5190f26794ab80ed7a702"
+checksum = "ae4606aea513f0e614497c0c4556d0e39f51a8434d9d97e592d32f9e615d4232"
 dependencies = [
  "async-stream",
- "base64 0.20.0",
+ "base64 0.22.1",
  "bytes",
  "futures",
- "http",
- "http-body",
+ "http 1.1.0",
+ "http-body 1.0.0",
+ "http-body-util",
  "http-serde",
- "hyper",
+ "hyper 1.3.1",
+ "hyper-util",
  "lambda_runtime_api_client",
+ "pin-project",
  "serde",
  "serde_json",
  "serde_path_to_error",
  "tokio",
  "tokio-stream",
  "tower",
+ "tower-layer",
  "tracing",
 ]
 
 [[package]]
 name = "lambda_runtime_api_client"
-version = "0.8.0"
+version = "0.11.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "690c5ae01f3acac8c9c3348b556fc443054e9b7f1deaf53e9ebab716282bf0ed"
+checksum = "c90a10f094475a34a04da2be11686c4dcfe214d93413162db9ffdff3d3af293a"
 dependencies = [
- "http",
- "hyper",
+ "bytes",
+ "futures-channel",
+ "futures-util",
+ "http 1.1.0",
+ "http-body 1.0.0",
+ "http-body-util",
+ "hyper 1.3.1",
+ "hyper-util",
  "tokio",
+ "tower",
  "tower-service",
+ "tracing",
+ "tracing-subscriber",
 ]
 
 [[package]]
@@ -2138,6 +2480,12 @@ version = "1.4.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "e2abad23fbc42b3700f2f279844dc832adb2b2eb069b2df918f455c4e18cc646"
 
+[[package]]
+name = "lazycell"
+version = "1.3.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "830d08ce1d1d941e6b30645f1a0eb5643013d835ce3779a5fc208261dbe10f55"
+
 [[package]]
 name = "lexical-core"
 version = "0.8.5"
@@ -2208,6 +2556,16 @@ version = "0.2.154"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "ae743338b92ff9146ce83992f766a31066a91a8c84a45e0e9f21e7cf6de6d346"
 
+[[package]]
+name = "libloading"
+version = "0.8.3"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "0c2a198fb6b0eada2a8df47933734e6d35d350665a33a3593d7164fa52c75c19"
+dependencies = [
+ "cfg-if",
+ "windows-targets 0.52.5",
+]
+
 [[package]]
 name = "linux-raw-sys"
 version = "0.4.13"
@@ -2247,6 +2605,15 @@ version = "0.4.21"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "90ed8c1e510134f979dbc4f070f87d4313098b704861a105fe34231c70a3901c"
 
+[[package]]
+name = "lru"
+version = "0.12.3"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "d3262e75e648fce39813cb56ac41f3c3e3f65217ebf3844d818d1f9398cfb0dc"
+dependencies = [
+ "hashbrown 0.14.5",
+]
+
 [[package]]
 name = "lzma-sys"
 version = "0.1.20"
@@ -2332,6 +2699,12 @@ dependencies = [
  "windows-sys 0.48.0",
 ]
 
+[[package]]
+name = "mirai-annotations"
+version = "1.12.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "c9be0862c1b3f26a88803c4a49de6889c10e608b3ee9344e6ef5b45fb37ad3d1"
+
 [[package]]
 name = "mutually_exclusive_features"
 version = "0.0.3"
@@ -2350,9 +2723,9 @@ dependencies = [
 
 [[package]]
 name = "noodles"
-version = "0.65.0"
+version = "0.74.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "38db1833ba39368f7a855c5b9a8412729a61dd86b2563e1a3bdb02aecbe92a3c"
+checksum = "8903a0299daf4f072f2e601c74c29c861abdfd2427366e727b8d8afbbde8cbcc"
 dependencies = [
  "noodles-bam",
  "noodles-bcf",
@@ -2362,6 +2735,7 @@ dependencies = [
  "noodles-csi",
  "noodles-fasta",
  "noodles-fastq",
+ "noodles-gff",
  "noodles-sam",
  "noodles-tabix",
  "noodles-vcf",
@@ -2369,9 +2743,9 @@ dependencies = [
 
 [[package]]
 name = "noodles-bam"
-version = "0.56.0"
+version = "0.63.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d3189e8ecee801ab5c3f4ea9908c4196b429137d8d35d733f00f6681f9188be7"
+checksum = "3ede0b1e0b8e0e03f21c692ad38473dfe95c3650317650205c29c9a682c4a5a6"
 dependencies = [
  "bit-vec",
  "bstr",
@@ -2388,9 +2762,9 @@ dependencies = [
 
 [[package]]
 name = "noodles-bcf"
-version = "0.46.0"
+version = "0.54.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "1561dbba3a09a61020b805a598b3d7c50841491c915523e0e4987f67286886f1"
+checksum = "924e8b050dc7d9b6e4933da612e45743aaf5450094dab069ed9cddb79700e193"
 dependencies = [
  "byteorder",
  "futures",
@@ -2404,9 +2778,9 @@ dependencies = [
 
 [[package]]
 name = "noodles-bgzf"
-version = "0.26.0"
+version = "0.30.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "8970db2e84adb1007377dd3988258d7a64e3fc4c05602ebf94e1f8cba207c030"
+checksum = "13f54d4840fd26ed94103ded9524aa5fdd757255a556f24653d162c0a45c47e8"
 dependencies = [
  "byteorder",
  "bytes",
@@ -2420,18 +2794,21 @@ dependencies = [
 
 [[package]]
 name = "noodles-core"
-version = "0.14.0"
+version = "0.15.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "7336c3be652de4e05444c9b12a32331beb5ba3316e8872d92bfdd8ef3b06c282"
+checksum = "c5a8c6b020d1205abef2b0fab4463a6c5ecc3c8f4d561ca8b0d1a42323376200"
+dependencies = [
+ "bstr",
+]
 
 [[package]]
 name = "noodles-cram"
-version = "0.56.0"
+version = "0.63.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "34a70ebb5bc7ff2d07ce96c0568691e57be421c121103ebef10cf02a63d7d400"
+checksum = "8e16052ef0d5da67e94e8372c18daf6bd288eebe4fc44654e9b944e3da9d8c7f"
 dependencies = [
  "async-compression",
- "bitflags 2.5.0",
+ "bitflags",
  "bstr",
  "byteorder",
  "bytes",
@@ -2451,9 +2828,9 @@ dependencies = [
 
 [[package]]
 name = "noodles-csi"
-version = "0.30.0"
+version = "0.35.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "a60dfe0919f7ecbd081a82eb1d32e8f89f9041932d035fe8309073c8c01277bf"
+checksum = "beb1618ca2aa88662d387197a188686105d6b5e25f6959c52b766276cbfc4620"
 dependencies = [
  "bit-vec",
  "byteorder",
@@ -2465,9 +2842,9 @@ dependencies = [
 
 [[package]]
 name = "noodles-fasta"
-version = "0.33.0"
+version = "0.38.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "5e9e953e4e90e6c96e6a384598ebf2ab6d2f5add259ff05a194cf635e892c980"
+checksum = "8bf9160022ada6c905f4e54aa27dd1ebde8d48faf6fb4dcd0f3ec423adc241ec"
 dependencies = [
  "bytes",
  "memchr",
@@ -2487,13 +2864,28 @@ dependencies = [
  "tokio",
 ]
 
+[[package]]
+name = "noodles-gff"
+version = "0.33.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "578b6efaf5c3f029720af4c8590e34fd38e214666971d665a52e3566830170d0"
+dependencies = [
+ "futures",
+ "indexmap 2.2.6",
+ "noodles-bgzf",
+ "noodles-core",
+ "noodles-csi",
+ "percent-encoding",
+ "tokio",
+]
+
 [[package]]
 name = "noodles-sam"
-version = "0.53.0"
+version = "0.60.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "1f0d8e441368374f6e144989f823fd7c05e58cdaa3f97d22bb4d75b534327b87"
+checksum = "0ec6452e8ed9f20ef043dce35e09ed58f1c34834cd941e987458a66e8fa66fa0"
 dependencies = [
- "bitflags 2.5.0",
+ "bitflags",
  "bstr",
  "futures",
  "indexmap 2.2.6",
@@ -2507,9 +2899,9 @@ dependencies = [
 
 [[package]]
 name = "noodles-tabix"
-version = "0.36.0"
+version = "0.41.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "cc1ab29335a68d0c2bdf41460a67714ca69e23a1cbeb950ac5c38a9afa446a62"
+checksum = "0cc110f78cb406f69f42c482d1986526c590b7295f37f0e37f1fc380413400ef"
 dependencies = [
  "bit-vec",
  "byteorder",
@@ -2522,9 +2914,9 @@ dependencies = [
 
 [[package]]
 name = "noodles-vcf"
-version = "0.49.0"
+version = "0.57.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "2e1f2fa749afaccadc596ec55ccb7bdcd8101fa79f8382384223c0dbae3e245b"
+checksum = "4df6e162ec2e898581b5ccf5e8972e376a7c41807061b66152280dea2c53a989"
 dependencies = [
  "futures",
  "indexmap 2.2.6",
@@ -2635,6 +3027,17 @@ version = "0.1.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "b15813163c1d831bf4a13c3610c05c0d03b39feb07f7e09fa234dac9b15aaf39"
 
+[[package]]
+name = "p256"
+version = "0.11.1"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "51f44edd08f51e2ade572f141051021c5af22677e42b7dd28a88155151c33594"
+dependencies = [
+ "ecdsa",
+ "elliptic-curve",
+ "sha2",
+]
+
 [[package]]
 name = "parking_lot"
 version = "0.12.2"
@@ -2753,6 +3156,16 @@ version = "0.1.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "8b870d8c151b6f2fb93e84a13146138f05d02ed11c7e7c54f8826aaaf7c9f184"
 
+[[package]]
+name = "pkcs8"
+version = "0.9.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "9eca2c590a5f85da82668fa685c09ce2888b9430e83299debf1f34b65fd4a4ba"
+dependencies = [
+ "der",
+ "spki",
+]
+
 [[package]]
 name = "pkg-config"
 version = "0.3.30"
@@ -2809,6 +3222,16 @@ dependencies = [
  "yansi 0.5.1",
 ]
 
+[[package]]
+name = "prettyplease"
+version = "0.2.20"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "5f12335488a2f3b0a83b14edad48dca9879ce89b2edd10e80237e4e852dd645e"
+dependencies = [
+ "proc-macro2",
+ "syn 2.0.61",
+]
+
 [[package]]
 name = "proc-macro-error"
 version = "1.0.4"
@@ -2937,12 +3360,13 @@ dependencies = [
 
 [[package]]
 name = "rcgen"
-version = "0.12.1"
+version = "0.13.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "48406db8ac1f3cbc7dcdb56ec355343817958a356ff430259bb07baf7607e1e1"
+checksum = "54077e1872c46788540de1ea3d7f4ccb1983d12f9aa909b234468676c1a36779"
 dependencies = [
  "pem",
- "ring 0.17.8",
+ "ring",
+ "rustls-pki-types",
  "time",
  "yasna",
 ]
@@ -2953,7 +3377,7 @@ version = "0.5.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "469052894dcb553421e483e4209ee581a45100d31b4018de03e5a7ad86374a7e"
 dependencies = [
- "bitflags 2.5.0",
+ "bitflags",
 ]
 
 [[package]]
@@ -2988,6 +3412,12 @@ dependencies = [
  "regex-syntax 0.8.3",
 ]
 
+[[package]]
+name = "regex-lite"
+version = "0.1.5"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "30b661b2f27137bdbc16f00eda72866a92bb28af1753ffbd56744fb6e2e9cd8e"
+
 [[package]]
 name = "regex-syntax"
 version = "0.6.29"
@@ -3002,20 +3432,21 @@ checksum = "adad44e29e4c806119491a7f06f03de4d1af22c3a680dd47f1e6e179439d1f56"
 
 [[package]]
 name = "reqwest"
-version = "0.11.27"
+version = "0.12.4"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "dd67538700a17451e7cba03ac727fb961abb7607553461627b97de0b89cf4a62"
+checksum = "566cafdd92868e0939d3fb961bd0dc25fcfaaed179291093b3d43e6b3150ea10"
 dependencies = [
- "base64 0.21.7",
+ "base64 0.22.1",
  "bytes",
- "encoding_rs",
+ "futures-channel",
  "futures-core",
  "futures-util",
- "h2",
- "http",
- "http-body",
- "hyper",
- "hyper-rustls",
+ "http 1.1.0",
+ "http-body 1.0.0",
+ "http-body-util",
+ "hyper 1.3.1",
+ "hyper-rustls 0.26.0",
+ "hyper-util",
  "ipnet",
  "js-sys",
  "log",
@@ -3023,15 +3454,15 @@ dependencies = [
  "once_cell",
  "percent-encoding",
  "pin-project-lite",
- "rustls",
- "rustls-pemfile",
+ "rustls 0.22.4",
+ "rustls-pemfile 2.1.2",
+ "rustls-pki-types",
  "serde",
  "serde_json",
  "serde_urlencoded",
- "sync_wrapper",
- "system-configuration",
+ "sync_wrapper 0.1.2",
  "tokio",
- "tokio-rustls",
+ "tokio-rustls 0.25.0",
  "tokio-util",
  "tower-service",
  "url",
@@ -3044,18 +3475,14 @@ dependencies = [
 ]
 
 [[package]]
-name = "ring"
-version = "0.16.20"
+name = "rfc6979"
+version = "0.3.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "3053cf52e236a3ed746dfc745aa9cacf1b791d846bdaf412f60a8d7d6e17c8fc"
+checksum = "7743f17af12fa0b03b803ba12cd6a8d9483a587e89c69445e3909655c0b9fabb"
 dependencies = [
- "cc",
- "libc",
- "once_cell",
- "spin 0.5.2",
- "untrusted 0.7.1",
- "web-sys",
- "winapi",
+ "crypto-bigint 0.4.9",
+ "hmac",
+ "zeroize",
 ]
 
 [[package]]
@@ -3068,8 +3495,8 @@ dependencies = [
  "cfg-if",
  "getrandom",
  "libc",
- "spin 0.9.8",
- "untrusted 0.9.0",
+ "spin",
+ "untrusted",
  "windows-sys 0.52.0",
 ]
 
@@ -3088,6 +3515,12 @@ version = "0.1.24"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "719b953e2095829ee67db738b3bfa9fa368c94900df327b3f07fe6e794d2fe1f"
 
+[[package]]
+name = "rustc-hash"
+version = "1.1.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "08d43f7aa6b08d49f382cde6a7982047c3426db949b1424bc4b7ec9ae12c6ce2"
+
 [[package]]
 name = "rustc_version"
 version = "0.4.0"
@@ -3103,7 +3536,7 @@ version = "0.38.34"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "70dc5ec042f7a43c4a73241207cecc9873a06d45debb38b329f8541d85c2730f"
 dependencies = [
- "bitflags 2.5.0",
+ "bitflags",
  "errno",
  "libc",
  "linux-raw-sys",
@@ -3117,11 +3550,40 @@ source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "3f56a14d1f48b391359b22f731fd4bd7e43c97f3c50eee276f3aa09c94784d3e"
 dependencies = [
  "log",
- "ring 0.17.8",
- "rustls-webpki",
+ "ring",
+ "rustls-webpki 0.101.7",
  "sct",
 ]
 
+[[package]]
+name = "rustls"
+version = "0.22.4"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "bf4ef73721ac7bcd79b2b315da7779d8fc09718c6b3d2d1b2d94850eb8c18432"
+dependencies = [
+ "log",
+ "ring",
+ "rustls-pki-types",
+ "rustls-webpki 0.102.4",
+ "subtle",
+ "zeroize",
+]
+
+[[package]]
+name = "rustls"
+version = "0.23.7"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "ebbbdb961df0ad3f2652da8f3fdc4b36122f568f968f45ad3316f26c025c677b"
+dependencies = [
+ "aws-lc-rs",
+ "log",
+ "once_cell",
+ "rustls-pki-types",
+ "rustls-webpki 0.102.4",
+ "subtle",
+ "zeroize",
+]
+
 [[package]]
 name = "rustls-native-certs"
 version = "0.6.3"
@@ -3129,7 +3591,7 @@ source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "a9aace74cb666635c918e9c12bc0d348266037aa8eb599b5cba565709a8dff00"
 dependencies = [
  "openssl-probe",
- "rustls-pemfile",
+ "rustls-pemfile 1.0.4",
  "schannel",
  "security-framework",
 ]
@@ -3143,14 +3605,42 @@ dependencies = [
  "base64 0.21.7",
 ]
 
+[[package]]
+name = "rustls-pemfile"
+version = "2.1.2"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "29993a25686778eb88d4189742cd713c9bce943bc54251a33509dc63cbacf73d"
+dependencies = [
+ "base64 0.22.1",
+ "rustls-pki-types",
+]
+
+[[package]]
+name = "rustls-pki-types"
+version = "1.7.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "976295e77ce332211c0d24d92c0e83e50f5c5f046d11082cea19f3df13a3562d"
+
 [[package]]
 name = "rustls-webpki"
 version = "0.101.7"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "8b6275d1ee7a1cd780b64aca7726599a1dbc893b1e64144529e55c3c2f745765"
 dependencies = [
- "ring 0.17.8",
- "untrusted 0.9.0",
+ "ring",
+ "untrusted",
+]
+
+[[package]]
+name = "rustls-webpki"
+version = "0.102.4"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "ff448f7e92e913c4b7d4c6d8e4540a1724b319b4152b8aef6d4cf8339712b33e"
+dependencies = [
+ "aws-lc-rs",
+ "ring",
+ "rustls-pki-types",
+ "untrusted",
 ]
 
 [[package]]
@@ -3167,9 +3657,9 @@ checksum = "f3cb5ba0dc43242ce17de99c180e96db90b235b8a9fdc9543c96d2209116bd9f"
 
 [[package]]
 name = "s3s"
-version = "0.8.1"
+version = "0.10.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "17419b26b83f810a49eb1087213e889da16b446f9cf5149aaad777c0b1e5f56f"
+checksum = "67e6cdc8002708b435946eec39afa13c43e4288d1de6316a12816e4cfaaa6c2c"
 dependencies = [
  "arrayvec",
  "async-trait",
@@ -3182,9 +3672,10 @@ dependencies = [
  "futures",
  "hex-simd",
  "hmac",
- "http-body",
+ "http-body 1.0.0",
+ "http-body-util",
  "httparse",
- "hyper",
+ "hyper 1.3.1",
  "itoa",
  "memchr",
  "mime",
@@ -3207,30 +3698,27 @@ dependencies = [
 
 [[package]]
 name = "s3s-aws"
-version = "0.8.1"
+version = "0.10.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "355d5e4fc3dad032b0c719057b3632713caee110b4ea231f4d37b44287eee8ea"
+checksum = "6de0d6542f9aa260bd219cf69caf4a5d16786114a4fd834df78d6ae85cfaf10f"
 dependencies = [
  "async-trait",
  "aws-sdk-s3",
- "aws-smithy-http",
  "aws-smithy-runtime-api",
  "aws-smithy-types",
  "aws-smithy-types-convert",
- "bytes",
- "futures",
- "hyper",
+ "hyper 1.3.1",
  "s3s",
- "sync_wrapper",
+ "sync_wrapper 1.0.1",
  "tracing",
  "transform-stream",
 ]
 
 [[package]]
 name = "s3s-fs"
-version = "0.8.1"
+version = "0.10.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "cfed24ce7b786e2d8979f0468e7745482cc1f5114ed75dd214c71e5c5620d87e"
+checksum = "12416a376cc964d0730718c8e03e2c0e414c1da48c20b1057ca4cad29059b308"
 dependencies = [
  "async-trait",
  "base64-simd",
@@ -3290,8 +3778,22 @@ version = "0.7.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "da046153aa2352493d6cb7da4b6e5c0c057d8a1d0a9aa8560baffdd945acd414"
 dependencies = [
- "ring 0.17.8",
- "untrusted 0.9.0",
+ "ring",
+ "untrusted",
+]
+
+[[package]]
+name = "sec1"
+version = "0.3.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "3be24c1842290c45df0a7bf069e0c268a747ad05a192f2fd7dcfdbc1cba40928"
+dependencies = [
+ "base16ct",
+ "der",
+ "generic-array",
+ "pkcs8",
+ "subtle",
+ "zeroize",
 ]
 
 [[package]]
@@ -3300,7 +3802,7 @@ version = "2.11.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "c627723fd09706bacdb5cf41499e95098555af3c3c29d014dc3c458ef6be11c0"
 dependencies = [
- "bitflags 2.5.0",
+ "bitflags",
  "core-foundation",
  "core-foundation-sys",
  "libc",
@@ -3457,6 +3959,12 @@ dependencies = [
  "lazy_static",
 ]
 
+[[package]]
+name = "shlex"
+version = "1.3.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "0fda2ff0d084019ba4d7c6f371c95d8fd75ce3524c3cb8fb653a3023f6323e64"
+
 [[package]]
 name = "signal-hook-registry"
 version = "1.4.2"
@@ -3466,6 +3974,16 @@ dependencies = [
  "libc",
 ]
 
+[[package]]
+name = "signature"
+version = "1.6.4"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "74233d3b3b2f6d4b006dc19dee745e73e2a6bfb6f93607cd3b02bd5b00797d7c"
+dependencies = [
+ "digest",
+ "rand_core",
+]
+
 [[package]]
 name = "simdutf8"
 version = "0.1.4"
@@ -3499,15 +4017,19 @@ dependencies = [
 
 [[package]]
 name = "spin"
-version = "0.5.2"
+version = "0.9.8"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "6e63cff320ae2c57904679ba7cb63280a3dc4613885beafb148ee7bf9aa9042d"
+checksum = "6980e8d7511241f8acf4aebddbb1ff938df5eebe98691418c4468d0b72a96a67"
 
 [[package]]
-name = "spin"
-version = "0.9.8"
+name = "spki"
+version = "0.6.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "6980e8d7511241f8acf4aebddbb1ff938df5eebe98691418c4468d0b72a96a67"
+checksum = "67cf02bbac7a337dc36e4f5a693db6c21e7863f45070f7064577eb4367a3212b"
+dependencies = [
+ "base64ct",
+ "der",
+]
 
 [[package]]
 name = "static_assertions"
@@ -3562,25 +4084,10 @@ source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "2047c6ded9c721764247e62cd3b03c09ffc529b2ba5b10ec482ae507a4a70160"
 
 [[package]]
-name = "system-configuration"
-version = "0.5.1"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "ba3a3adc5c275d719af8cb4272ea1c4a6d668a777f37e115f6d11ddbc1c8e0e7"
-dependencies = [
- "bitflags 1.3.2",
- "core-foundation",
- "system-configuration-sys",
-]
-
-[[package]]
-name = "system-configuration-sys"
-version = "0.5.0"
+name = "sync_wrapper"
+version = "1.0.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "a75fb188eb626b924683e3b95e3a48e63551fcfb51949de2f06a9d91dbee93c9"
-dependencies = [
- "core-foundation-sys",
- "libc",
-]
+checksum = "a7065abeca94b6a8a577f9bd45aa0867a2238b74e8eb67cf10d492bc39351394"
 
 [[package]]
 name = "tempfile"
@@ -3716,7 +4223,29 @@ version = "0.24.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "c28327cf380ac148141087fbfb9de9d7bd4e84ab5d2c28fbc911d753de8a7081"
 dependencies = [
- "rustls",
+ "rustls 0.21.12",
+ "tokio",
+]
+
+[[package]]
+name = "tokio-rustls"
+version = "0.25.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "775e0c0f0adb3a2f22a00c4745d728b479985fc15ee7ca6a2608388c5569860f"
+dependencies = [
+ "rustls 0.22.4",
+ "rustls-pki-types",
+ "tokio",
+]
+
+[[package]]
+name = "tokio-rustls"
+version = "0.26.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "0c7bc40d0e5a97695bb96e27995cd3a08538541b0a846f65bba7a359f36700d4"
+dependencies = [
+ "rustls 0.23.7",
+ "rustls-pki-types",
  "tokio",
 ]
 
@@ -3797,16 +4326,16 @@ dependencies = [
 
 [[package]]
 name = "tower-http"
-version = "0.4.4"
+version = "0.5.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "61c5bb1d698276a2443e5ecfabc1008bf15a36c12e6a7176e7bf089ea9131140"
+checksum = "1e9cd434a998747dd2c4276bc96ee2e0c7a2eadf3cae88e52be55a05fa9053f5"
 dependencies = [
- "bitflags 2.5.0",
+ "bitflags",
  "bytes",
- "futures-core",
  "futures-util",
- "http",
- "http-body",
+ "http 1.1.0",
+ "http-body 1.0.0",
+ "http-body-util",
  "http-range-header",
  "httpdate",
  "mime",
@@ -3990,12 +4519,6 @@ dependencies = [
  "tinyvec",
 ]
 
-[[package]]
-name = "untrusted"
-version = "0.7.1"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "a156c684c91ea7d62626509bce3cb4e1d9ed5c4d978f7b4352658f96a4c26b4a"
-
 [[package]]
 name = "untrusted"
 version = "0.9.0"
@@ -4168,9 +4691,24 @@ dependencies = [
 
 [[package]]
 name = "webpki-roots"
-version = "0.25.4"
+version = "0.26.1"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "b3de34ae270483955a94f4b21bdaaeb83d508bb84a01435f393818edb0012009"
+dependencies = [
+ "rustls-pki-types",
+]
+
+[[package]]
+name = "which"
+version = "4.4.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "5f20c57d8d7db6d3b86154206ae5d8fba62dd39573114de97c2cb0578251f8e1"
+checksum = "87ba24419a2078cd2b0f2ede2691b6c66d8e47836da3b6db8265ebad47afbfc7"
+dependencies = [
+ "either",
+ "home",
+ "once_cell",
+ "rustix",
+]
 
 [[package]]
 name = "winapi"
@@ -4362,9 +4900,9 @@ dependencies = [
 
 [[package]]
 name = "winreg"
-version = "0.50.0"
+version = "0.52.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "524e57b2c537c0f9b1e69f1965311ec12182b4122e45035b1508cd24d2adadb1"
+checksum = "a277a57398d4bfa075df44f501a17cfdf8542d224f0d36095a2adc7aee4ef0a5"
 dependencies = [
  "cfg-if",
  "windows-sys 0.48.0",
diff --git a/htsget-actix/Cargo.toml b/htsget-actix/Cargo.toml
index 45bb84cd3..3e5248a8b 100644
--- a/htsget-actix/Cargo.toml
+++ b/htsget-actix/Cargo.toml
@@ -2,7 +2,7 @@
 name = "htsget-actix"
 version = "0.6.0"
 rust-version = "1.74"
-authors = ["Daniel del Castillo de la Rosa <delcastillodelarosadaniel@gmail.com>", "Marko Malenic <mmalenic1@gmail.com>"]
+authors = ["Daniel del Castillo de la Rosa <delcastillodelarosadaniel@gmail.com>", "Marko Malenic <mmalenic1@gmail.com>", "Roman Valls Guimera <brainstorm@nopcode.org>"]
 edition = "2021"
 license = "MIT"
 description = "A webserver instance of htsget-rs configured using htsget-config."
@@ -16,11 +16,12 @@ url-storage = ["htsget-config/url-storage", "htsget-search/url-storage", "htsget
 default = []
 
 [dependencies]
-actix-web = { version = "4", features = ["rustls-0_21"] }
-actix-cors = "0.6"
+actix-web = { version = "4", features = ["rustls-0_23"] }
+actix-cors = "0.7"
+http_1 = { package = "http", version = "1" }
 http = "0.2"
-rustls-pemfile = "1.0"
-serde = { version = "1.0", features = ["derive"] }
+rustls-pemfile = "2"
+serde = { version = "1", features = ["derive"] }
 serde_json = "1"
 futures-util = { version = "0.3" }
 htsget-http = { version = "0.4.13", path = "../htsget-http", default-features = false }
@@ -28,7 +29,7 @@ htsget-search = { version = "0.7.0", path = "../htsget-search", default-features
 htsget-config = { version = "0.9.0", path = "../htsget-config", default-features = false }
 htsget-test = { version = "0.6.0", path = "../htsget-test", features = ["http"], default-features = false }
 futures = { version = "0.3" }
-tokio = { version = "1.28", features = ["macros", "rt-multi-thread"] }
+tokio = { version = "1", features = ["macros", "rt-multi-thread"] }
 
 tracing-actix-web = "0.7"
 tracing = "0.1"
@@ -37,8 +38,8 @@ tracing = "0.1"
 async-trait = "0.1"
 
 criterion = { version = "0.5", features = ["async_tokio"] }
-reqwest = { version = "0.11", default-features = false, features = ["json", "blocking", "rustls-tls"] }
-tempfile = "3.5"
+reqwest = { version = "0.12", default-features = false, features = ["json", "blocking", "rustls-tls"] }
+tempfile = "3"
 
 [[bench]]
 name = "request-benchmarks"
diff --git a/htsget-actix/src/handlers/mod.rs b/htsget-actix/src/handlers/mod.rs
index edbe7014f..66d1d87c7 100644
--- a/htsget-actix/src/handlers/mod.rs
+++ b/htsget-actix/src/handlers/mod.rs
@@ -2,7 +2,7 @@ use std::collections::HashMap;
 
 use actix_web::web::{Path, Query};
 use actix_web::{http::StatusCode, Either, HttpRequest, Responder};
-use http::HeaderMap as HttpHeaderMap;
+use http::{HeaderMap as HttpHeaderMap, HeaderName, Method};
 
 use htsget_config::types::{JsonResponse, Request};
 use htsget_http::Result;
@@ -37,7 +37,11 @@ fn handle_response(response: Result<JsonResponse>) -> Either<impl Responder, imp
   match response {
     Err(error) => {
       let (json, status_code) = error.to_json_representation();
-      Either::Left(PrettyJson(json).customize().with_status(status_code))
+      Either::Left(
+        PrettyJson(json)
+          .customize()
+          .with_status(HttpVersionCompat::status_code_1_to_0_2(status_code)),
+      )
     }
     Ok(json) => Either::Right(PrettyJson(json).customize().with_status(StatusCode::OK)),
   }
@@ -53,6 +57,47 @@ fn extract_request(
   Request::new(
     path.into_inner(),
     query,
-    HeaderMap::from(&http_request).into_inner(),
+    HttpVersionCompat::header_map_0_2_to_1(HeaderMap::from(&http_request).into_inner()),
   )
 }
+
+// Todo, remove this when actix-web starts using http 1.0.
+pub(crate) struct HttpVersionCompat;
+
+impl HttpVersionCompat {
+  pub(crate) fn header_names_1_to_0_2(header_name: Vec<http_1::HeaderName>) -> Vec<HeaderName> {
+    header_name
+      .iter()
+      .map(|name| name.as_str().parse().ok())
+      .collect::<Option<_>>()
+      .unwrap_or_default()
+  }
+
+  pub(crate) fn methods_0_2_to_1(method: Vec<http_1::Method>) -> Vec<Method> {
+    method
+      .iter()
+      .map(|method| method.as_str().parse().ok())
+      .collect::<Option<_>>()
+      .unwrap_or_default()
+  }
+
+  pub(crate) fn header_map_0_2_to_1(header_map: HttpHeaderMap) -> http_1::HeaderMap {
+    // Silently ignore incompatible headers. This isn't ideal but it shouldn't cause any errors.
+    header_map
+      .iter()
+      .map(|(name, value)| {
+        let name = name.as_str().parse().ok()?;
+        let value = value.to_str().ok()?.parse().ok()?;
+
+        Some((name, value))
+      })
+      .collect::<Option<Vec<_>>>()
+      .map(FromIterator::from_iter)
+      .unwrap_or_default()
+  }
+
+  pub(crate) fn status_code_1_to_0_2(status_code: http_1::StatusCode) -> StatusCode {
+    // Report an error if the status code is not convertible
+    StatusCode::from_u16(status_code.as_u16()).unwrap_or(StatusCode::INTERNAL_SERVER_ERROR)
+  }
+}
diff --git a/htsget-actix/src/lib.rs b/htsget-actix/src/lib.rs
index 7e103db30..0bc2faadc 100644
--- a/htsget-actix/src/lib.rs
+++ b/htsget-actix/src/lib.rs
@@ -14,7 +14,7 @@ use htsget_search::htsget::from_storage::HtsGetFromStorage;
 use htsget_search::htsget::HtsGet;
 use htsget_search::storage::local::LocalStorage;
 
-use crate::handlers::{get, post, reads_service_info, variants_service_info};
+use crate::handlers::{get, post, reads_service_info, variants_service_info, HttpVersionCompat};
 
 pub mod handlers;
 
@@ -78,7 +78,9 @@ pub fn configure_cors(cors: CorsConfig) -> Cors {
     .allow_headers()
     .apply_any(|cors_layer| cors_layer.allow_any_header(), cors_layer);
   cors_layer = cors.allow_headers().apply_list(
-    |cors_layer, headers| cors_layer.allowed_headers(headers.clone()),
+    |cors_layer, headers| {
+      cors_layer.allowed_headers(HttpVersionCompat::header_names_1_to_0_2(headers.clone()))
+    },
     cors_layer,
   );
 
@@ -86,7 +88,9 @@ pub fn configure_cors(cors: CorsConfig) -> Cors {
     .allow_methods()
     .apply_any(|cors_layer| cors_layer.allow_any_method(), cors_layer);
   cors_layer = cors.allow_methods().apply_list(
-    |cors_layer, methods| cors_layer.allowed_methods(methods.clone()),
+    |cors_layer, methods| {
+      cors_layer.allowed_methods(HttpVersionCompat::methods_0_2_to_1(methods.clone()))
+    },
     cors_layer,
   );
 
@@ -94,7 +98,9 @@ pub fn configure_cors(cors: CorsConfig) -> Cors {
     .expose_headers()
     .apply_any(|cors_layer| cors_layer.expose_any_header(), cors_layer);
   cors_layer = cors.expose_headers().apply_list(
-    |cors_layer, headers| cors_layer.expose_headers(headers.clone()),
+    |cors_layer, headers| {
+      cors_layer.expose_headers(HttpVersionCompat::header_names_1_to_0_2(headers.clone()))
+    },
     cors_layer,
   );
 
@@ -131,7 +137,7 @@ pub fn run_server<H: HtsGet + Clone + Send + Sync + 'static>(
     }
     Some(tls) => {
       info!("using TLS ticket server");
-      server.bind_rustls_021(addr, tls.into_inner())?
+      server.bind_rustls_0_23(addr, tls.into_inner())?
     }
   };
 
@@ -208,7 +214,7 @@ mod tests {
       let path = self.get_config().data_server().local_path().to_path_buf();
       tokio::spawn(async move { server.serve(path).await.unwrap() });
 
-      expected_url_path(self.get_config(), addr)
+      expected_url_path(self.get_config(), addr.unwrap())
     }
 
     fn get_config(&self) -> &Config {
@@ -232,10 +238,12 @@ mod tests {
 
       TestResponse::new(
         status,
-        headers
-          .drain()
-          .map(|(name, value)| (name.unwrap(), value))
-          .collect(),
+        HttpVersionCompat::header_map_0_2_to_1(
+          headers
+            .drain()
+            .map(|(name, value)| (name.unwrap(), value))
+            .collect(),
+        ),
         bytes,
         expected_path,
       )
diff --git a/htsget-config/Cargo.toml b/htsget-config/Cargo.toml
index 42893e612..b71844ca8 100644
--- a/htsget-config/Cargo.toml
+++ b/htsget-config/Cargo.toml
@@ -2,7 +2,7 @@
 name = "htsget-config"
 version = "0.9.0"
 rust-version = "1.74"
-authors = ["Daniel del Castillo de la Rosa <delcastillodelarosadaniel@gmail.com>", "Marko Malenic <mmalenic1@gmail.com>"]
+authors = ["Daniel del Castillo de la Rosa <delcastillodelarosadaniel@gmail.com>", "Marko Malenic <mmalenic1@gmail.com>", "Roman Valls Guimera <brainstorm@nopcode.org>"]
 edition = "2021"
 description = "Used to configure htsget-rs by using a config file or reading environment variables."
 license = "MIT"
@@ -12,33 +12,34 @@ repository = "https://github.com/umccr/htsget-rs"
 
 [features]
 s3-storage = []
-url-storage = ["reqwest"]
+url-storage = ["dep:reqwest"]
 default = []
 
 [dependencies]
-thiserror = "1.0"
+thiserror = "1"
 async-trait = "0.1"
-noodles = { version = "0.65", features = ["core"] }
-serde = { version = "1.0", features = ["derive"] }
-serde_with = "3.0"
-serde_regex = "1.1"
-regex = "1.8"
+noodles = { version = "0.74", features = ["core"] }
+serde = { version = "1", features = ["derive"] }
+serde_with = "3"
+serde_regex = "1"
+regex = "1"
 figment = { version = "0.10", features = ["env", "toml"] }
-clap = { version = "4.3", features = ["derive", "env", "cargo"] }
+clap = { version = "4", features = ["derive", "env", "cargo"] }
 tracing = "0.1"
 tracing-subscriber = { version = "0.3", features = ["registry", "env-filter", "ansi", "json"] }
 toml = "0.8"
-http = "0.2"
-http-serde = "1.1"
-rustls-pemfile = "1.0"
-rustls = "0.21"
+http = "1"
+http-serde = "2"
+rustls-pemfile = "2"
+rustls = "0.23"
+rustls-pki-types = "1"
 
 # url-storage
-reqwest = { version = "0.11", features = ["rustls-tls"], default-features = false, optional = true }
+reqwest = { version = "0.12", features = ["rustls-tls"], default-features = false, optional = true }
 
 [dev-dependencies]
-serde_json = "1.0"
+serde_json = "1"
 figment = { version = "0.10", features = ["test"] }
-tokio = { version = "1.28", features = ["macros", "rt-multi-thread"] }
-tempfile = "3.6"
-rcgen = "0.12"
+tokio = { version = "1", features = ["macros", "rt-multi-thread"] }
+tempfile = "3"
+rcgen = { version = "0.13", features = ["pem"] }
diff --git a/htsget-config/src/config/cors.rs b/htsget-config/src/config/cors.rs
index a480682cc..75f0546b1 100644
--- a/htsget-config/src/config/cors.rs
+++ b/htsget-config/src/config/cors.rs
@@ -48,6 +48,18 @@ impl<T, Tagged> AllowType<T, Tagged> {
     }
   }
 
+  /// Apply a function to the builder when the type is a List returning a Result.
+  pub fn try_apply_list<F, U, E>(&self, func: F, builder: U) -> Result<U, E>
+  where
+    F: FnOnce(U, &Vec<T>) -> Result<U, E>,
+  {
+    if let Self::List(list) = self {
+      func(builder, list)
+    } else {
+      Ok(builder)
+    }
+  }
+
   /// Apply a function to the builder when the type is tagged.
   pub fn apply_tagged<F, U>(&self, func: F, builder: U, tagged_type: &Tagged) -> U
   where
diff --git a/htsget-config/src/error.rs b/htsget-config/src/error.rs
index b92c42e68..9c2d68f4c 100644
--- a/htsget-config/src/error.rs
+++ b/htsget-config/src/error.rs
@@ -26,3 +26,9 @@ impl From<Error> for io::Error {
     io::Error::new(io::ErrorKind::Other, error.to_string())
   }
 }
+
+impl From<io::Error> for Error {
+  fn from(error: io::Error) -> Self {
+    Error::IoError(error.to_string())
+  }
+}
diff --git a/htsget-config/src/tls/client.rs b/htsget-config/src/tls/client.rs
index 2b1d80bec..7864543b0 100644
--- a/htsget-config/src/tls/client.rs
+++ b/htsget-config/src/tls/client.rs
@@ -1,10 +1,11 @@
 //! TLS configuration related to HTTP clients.
 //!
 
-use crate::error::Error;
 use crate::error::Error::IoError;
+use crate::error::{Error, Result};
 use crate::tls::RootCertStorePair;
 use crate::tls::{load_certs, read_bytes};
+use reqwest::{Certificate, Identity};
 use serde::Deserialize;
 
 /// A certificate and key pair used for TLS. Serialization is not implemented because there
@@ -12,18 +13,18 @@ use serde::Deserialize;
 #[derive(Deserialize, Debug, Clone, Default)]
 #[serde(try_from = "RootCertStorePair")]
 pub struct TlsClientConfig {
-  cert: Option<Vec<reqwest::Certificate>>,
-  identity: Option<reqwest::Identity>,
+  cert: Option<Vec<Certificate>>,
+  identity: Option<Identity>,
 }
 
 impl TlsClientConfig {
   /// Create a new TlsClientConfig.
-  pub fn new(cert: Option<Vec<reqwest::Certificate>>, identity: Option<reqwest::Identity>) -> Self {
+  pub fn new(cert: Option<Vec<Certificate>>, identity: Option<Identity>) -> Self {
     Self { cert, identity }
   }
 
   /// Get the inner client config.
-  pub fn into_inner(self) -> (Option<Vec<reqwest::Certificate>>, Option<reqwest::Identity>) {
+  pub fn into_inner(self) -> (Option<Vec<Certificate>>, Option<Identity>) {
     (self.cert, self.identity)
   }
 }
@@ -31,7 +32,7 @@ impl TlsClientConfig {
 impl TryFrom<RootCertStorePair> for TlsClientConfig {
   type Error = Error;
 
-  fn try_from(root_store_pair: RootCertStorePair) -> crate::error::Result<Self> {
+  fn try_from(root_store_pair: RootCertStorePair) -> Result<Self> {
     let (key_pair, root_store) = root_store_pair.into_inner();
 
     let cert = root_store
@@ -42,10 +43,10 @@ impl TryFrom<RootCertStorePair> for TlsClientConfig {
         certs
           .into_iter()
           .map(|cert| {
-            reqwest::Certificate::from_der(&cert.0)
+            Certificate::from_der(&cert)
               .map_err(|err| IoError(format!("failed to read certificate from pem: {}", err)))
           })
-          .collect::<crate::error::Result<Vec<_>>>()
+          .collect::<Result<Vec<_>>>()
       })
       .transpose()?;
 
@@ -55,7 +56,7 @@ impl TryFrom<RootCertStorePair> for TlsClientConfig {
         let key = read_bytes(pair.key)?;
         let certs = read_bytes(pair.cert)?;
 
-        reqwest::Identity::from_pem(&[certs, key].concat())
+        Identity::from_pem(&[certs, key].concat())
           .map_err(|err| IoError(format!("failed to pkcs8 pem identity: {}", err)))
       })
       .transpose()?;
diff --git a/htsget-config/src/tls/mod.rs b/htsget-config/src/tls/mod.rs
index 90c5881a6..30838140c 100644
--- a/htsget-config/src/tls/mod.rs
+++ b/htsget-config/src/tls/mod.rs
@@ -5,14 +5,17 @@
 pub mod client;
 
 use std::fs::File;
+use std::io;
 use std::io::{BufReader, Read};
 use std::path::{Path, PathBuf};
 
-use rustls::{Certificate, PrivateKey, ServerConfig};
-use rustls_pemfile::read_one;
+use rustls::ServerConfig;
+use rustls_pemfile::Item::{Pkcs1Key, Pkcs8Key, Sec1Key};
+use rustls_pemfile::{certs, read_one};
+use rustls_pki_types::{CertificateDer, PrivateKeyDer};
 use serde::{Deserialize, Serialize};
 
-use crate::error::Error::{IoError, ParseError};
+use crate::error::Error::ParseError;
 use crate::error::{Error, Result};
 use crate::types::Scheme;
 use crate::types::Scheme::{Http, Https};
@@ -52,20 +55,20 @@ pub struct CertificateKeyPairPath {
 }
 
 /// The certificate and key pair used for TLS.
-#[derive(Debug, Clone, PartialEq, Eq)]
+#[derive(Debug, PartialEq, Eq)]
 pub struct CertificateKeyPair {
-  certs: Vec<Certificate>,
-  key: PrivateKey,
+  certs: Vec<CertificateDer<'static>>,
+  key: PrivateKeyDer<'static>,
 }
 
 impl CertificateKeyPair {
   /// Create a new CertificateKeyPair.
-  pub fn new(certs: Vec<Certificate>, key: PrivateKey) -> Self {
+  pub fn new(certs: Vec<CertificateDer<'static>>, key: PrivateKeyDer<'static>) -> Self {
     Self { certs, key }
   }
 
   /// Get the owned certificate and private key.
-  pub fn into_inner(self) -> (Vec<Certificate>, PrivateKey) {
+  pub fn into_inner(self) -> (Vec<CertificateDer<'static>>, PrivateKeyDer<'static>) {
     (self.certs, self.key)
   }
 }
@@ -141,51 +144,39 @@ impl KeyPairScheme for Option<&TlsServerConfig> {
   }
 }
 
-/// Load a private key from a file. Supports RSA, PKCS8, and Sec1 encoded keys.
-pub fn load_key<P: AsRef<Path>>(key: P) -> Result<PrivateKey> {
-  let mut key_reader = BufReader::new(
-    File::open(key).map_err(|err| IoError(format!("failed to open key file: {}", err)))?,
-  );
+/// Loads the first private key from a file. Supports RSA, PKCS8, and Sec1 encoded EC keys.
+pub fn load_key<P: AsRef<Path>>(key_path: P) -> Result<PrivateKeyDer<'static>> {
+  let mut key_reader = BufReader::new(File::open(key_path)?);
 
   loop {
-    match read_one(&mut key_reader)
-      .map_err(|err| ParseError(format!("failed to parse private key: {}", err)))?
-    {
-      Some(rustls_pemfile::Item::RSAKey(key)) => return Ok(PrivateKey(key)),
-      Some(rustls_pemfile::Item::PKCS8Key(key)) => return Ok(PrivateKey(key)),
-      Some(rustls_pemfile::Item::ECKey(key)) => return Ok(PrivateKey(key)),
+    match read_one(&mut key_reader)? {
+      Some(Pkcs1Key(key)) => return Ok(PrivateKeyDer::from(key)),
+      Some(Pkcs8Key(key)) => return Ok(PrivateKeyDer::from(key)),
+      Some(Sec1Key(key)) => return Ok(PrivateKeyDer::from(key)),
+      // Silently disregard unknown private keys.
+      Some(_) => continue,
       None => break,
-      _ => {}
     }
   }
 
-  Err(ParseError("no key found in pem file".to_string()))
+  Err(ParseError("no keys found in pem file".to_string()))
 }
 
 /// Read byte data.
 pub fn read_bytes<P: AsRef<Path>>(path: P) -> Result<Vec<u8>> {
   let mut bytes = vec![];
-  File::open(path)
-    .map_err(|err| IoError(format!("failed to open certificate or key file: {}", err)))?
-    .read_to_end(&mut bytes)
-    .map_err(|err| IoError(format!("failed to read certificate or key bytes: {}", err)))?;
+  File::open(path)?.read_to_end(&mut bytes)?;
   Ok(bytes)
 }
 
 /// Load certificates from a file.
-pub fn load_certs<P: AsRef<Path>>(certs: P) -> Result<Vec<Certificate>> {
-  let mut cert_reader = BufReader::new(
-    File::open(certs).map_err(|err| IoError(format!("failed to open cert file: {}", err)))?,
-  );
-
-  let certs: Vec<Certificate> = rustls_pemfile::certs(&mut cert_reader)
-    .map_err(|err| ParseError(format!("failed to parse certificates: {}", err)))?
-    .into_iter()
-    .map(Certificate)
-    .collect();
+pub fn load_certs<P: AsRef<Path>>(certs_path: P) -> Result<Vec<CertificateDer<'static>>> {
+  let mut cert_reader = BufReader::new(File::open(certs_path)?);
 
+  let certs: Vec<CertificateDer> =
+    certs(&mut cert_reader).collect::<io::Result<Vec<CertificateDer>>>()?;
   if certs.is_empty() {
-    return Err(ParseError("no certificates found in pem file".to_string()));
+    return Err(ParseError("no certificates found in .pem file".to_string()));
   }
 
   Ok(certs)
@@ -196,7 +187,6 @@ pub fn tls_server_config(key_pair: CertificateKeyPair) -> Result<ServerConfig> {
   let (certs, key) = key_pair.into_inner();
 
   let mut config = ServerConfig::builder()
-    .with_safe_defaults()
     .with_no_client_auth()
     .with_single_cert(certs, key)
     .map_err(|err| ParseError(err.to_string()))?;
@@ -253,7 +243,7 @@ pub(crate) mod tests {
 
   pub(crate) fn with_test_certificates<F>(test: F)
   where
-    F: FnOnce(&Path, PrivateKey, Certificate),
+    F: FnOnce(&Path, PrivateKeyDer<'static>, CertificateDer<'static>),
   {
     let tmp_dir = TempDir::new().unwrap();
 
@@ -262,26 +252,19 @@ pub(crate) mod tests {
 
     let cert = generate_simple_self_signed(vec!["localhost".to_string()]).unwrap();
 
-    let key = cert.serialize_private_key_pem();
-    let cert = cert.serialize_pem().unwrap();
+    let key = cert.key_pair.serialize_pem();
+    let cert = cert.cert.pem();
 
     write(key_path, &key).unwrap();
     write(cert_path, &cert).unwrap();
 
-    let key = PrivateKey(
-      pkcs8_private_keys(&mut Cursor::new(key))
-        .unwrap()
-        .into_iter()
+    let key = PrivateKeyDer::from(
+      pkcs8_private_keys(&mut Cursor::new(key.clone()))
         .next()
-        .unwrap(),
-    );
-    let cert = Certificate(
-      certs(&mut Cursor::new(cert))
         .unwrap()
-        .into_iter()
-        .next()
         .unwrap(),
     );
+    let cert = certs(&mut Cursor::new(cert)).next().unwrap().unwrap();
 
     test(tmp_dir.path(), key, cert);
   }
diff --git a/htsget-http/Cargo.toml b/htsget-http/Cargo.toml
index 985c1de7a..f0da5a7ca 100644
--- a/htsget-http/Cargo.toml
+++ b/htsget-http/Cargo.toml
@@ -2,7 +2,7 @@
 name = "htsget-http"
 version = "0.4.13"
 rust-version = "1.74"
-authors = ["Daniel del Castillo de la Rosa <delcastillodelarosadaniel@gmail.com>", "Marko Malenic <mmalenic1@gmail.com>"]
+authors = ["Daniel del Castillo de la Rosa <delcastillodelarosadaniel@gmail.com>", "Marko Malenic <mmalenic1@gmail.com>", "Roman Valls Guimera <brainstorm@nopcode.org>"]
 edition = "2021"
 license = "MIT"
 description = "Crate for handling HTTP in htsget-rs."
@@ -16,12 +16,12 @@ url-storage = ["htsget-config/url-storage", "htsget-search/url-storage", "htsget
 default = []
 
 [dependencies]
-thiserror = "1.0"
-serde = { version = "1.0", features = ["derive"] }
-http = "0.2"
+thiserror = "1"
+serde = { version = "1", features = ["derive"] }
+http = "1"
 htsget-search = { version = "0.7.0", path = "../htsget-search", default-features = false }
 htsget-config = { version = "0.9.0", path = "../htsget-config", default-features = false }
 htsget-test = { version = "0.6.0", path = "../htsget-test", default-features = false }
 futures = { version = "0.3" }
-tokio = { version = "1.28", features = ["macros", "rt-multi-thread"] }
+tokio = { version = "1", features = ["macros", "rt-multi-thread"] }
 tracing = "0.1"
diff --git a/htsget-lambda/Cargo.toml b/htsget-lambda/Cargo.toml
index 0e0cdad78..156ad2b0c 100644
--- a/htsget-lambda/Cargo.toml
+++ b/htsget-lambda/Cargo.toml
@@ -16,23 +16,23 @@ url-storage = ["htsget-config/url-storage", "htsget-search/url-storage", "htsget
 default = []
 
 [dependencies]
-tokio = { version = "1.28", features = ["macros", "rt-multi-thread"] }
-tower-http = { version = "0.4", features = ["cors"] }
-lambda_http = { version = "0.8" }
-lambda_runtime = { version = "0.8" }
+tokio = { version = "1", features = ["macros", "rt-multi-thread"] }
+tower-http = { version = "0.5", features = ["cors"] }
+lambda_http = { version = "0.11" }
+lambda_runtime = { version = "0.11" }
 htsget-config = { version = "0.9.0", path = "../htsget-config", default-features = false }
 htsget-search = { version = "0.7.0", path = "../htsget-search", default-features = false }
 htsget-http = { version = "0.4.13", path = "../htsget-http", default-features = false }
 htsget-test = { version = "0.6.0", path = "../htsget-test", features = ["http"], default-features = false }
-serde = { version = "1.0" }
-serde_json = "1.0"
+serde = { version = "1" }
+serde_json = "1"
 mime = "0.3"
-regex = "1.8"
+regex = "1"
 tracing = "0.1"
 tracing-subscriber = "0.3"
-bytes = "1.4"
+bytes = "1"
 
 [dev-dependencies]
 async-trait = "0.1"
 query_map = { version = "0.7", features = ["url-query"] }
-tempfile = "3.6"
+tempfile = "3"
diff --git a/htsget-lambda/src/lib.rs b/htsget-lambda/src/lib.rs
index a18657ea7..452aa0630 100644
--- a/htsget-lambda/src/lib.rs
+++ b/htsget-lambda/src/lib.rs
@@ -711,7 +711,7 @@ mod tests {
     let path = config.data_server().local_path().to_path_buf();
     tokio::spawn(async move { server.serve(path).await.unwrap() });
 
-    expected_url_path(config, addr)
+    expected_url_path(config, addr.unwrap())
   }
 
   async fn endpoint_from_file(file_path: &str, class: Class, config: &Config) {
diff --git a/htsget-search/Cargo.toml b/htsget-search/Cargo.toml
index fb6e30b2c..9693ce37b 100644
--- a/htsget-search/Cargo.toml
+++ b/htsget-search/Cargo.toml
@@ -15,15 +15,15 @@ s3-storage = [
     "dep:bytes",
     "dep:aws-sdk-s3",
     "dep:aws-config",
+    "dep:pin-project-lite",
     "htsget-config/s3-storage",
     "htsget-test/s3-storage",
     "htsget-test/aws-mocks"
 ]
 url-storage = [
     "dep:bytes",
-    "hyper/client",
-    "reqwest",
-    "pin-project-lite",
+    "dep:reqwest",
+    "dep:pin-project-lite",
     "htsget-config/url-storage",
     "htsget-test/url-storage"
 ]
@@ -31,48 +31,49 @@ default = []
 
 [dependencies]
 # Axum server
-url = "2.3"
-hyper = { version = "0.14", features = ["http1", "http2", "server"] }
-tower-http = { version = "0.4", features = ["trace", "cors", "fs"] }
-http = "0.2"
-axum = "0.6"
-rustls-pemfile = "1.0"
+url = "2"
+hyper = { version = "1", features = ["http1", "http2", "server"] }
+hyper-util = "0.1"
+tower-http = { version = "0.5", features = ["trace", "cors", "fs"] }
+http = "1"
+axum = "0.7"
+rustls-pemfile = "2"
 tower = { version = "0.4", features = ["make"] }
 
 # Async
-tokio-rustls = "0.24"
-tokio = { version = "1.28", features = ["macros", "rt-multi-thread"] }
+tokio-rustls = "0.26"
+tokio = { version = "1", features = ["macros", "rt-multi-thread"] }
 tokio-util = { version = "0.7", features = ["io", "compat"] }
 futures = { version = "0.3" }
 futures-util = "0.3"
 async-trait = "0.1"
 
 # Noodles
-noodles = { version = "0.65", features = ["async", "core", "bgzf", "bam", "bcf", "cram", "csi", "sam", "tabix", "vcf"] }
+noodles = { version = "0.74", features = ["async", "core", "bgzf", "bam", "bcf", "cram", "csi", "sam", "tabix", "vcf"] }
 
 # Amazon S3
-bytes = { version = "1.4", optional = true }
-aws-sdk-s3 = { version = "0.34", optional = true }
-aws-config = { version = "0.56", optional = true }
+bytes = { version = "1", optional = true }
+aws-sdk-s3 = { version = "1", optional = true }
+aws-config = { version = "1", optional = true }
 
 # Url storage
-reqwest = { version = "0.11", features = ["rustls-tls", "stream"], default-features = false, optional = true }
+reqwest = { version = "0.12", features = ["rustls-tls", "stream"], default-features = false, optional = true }
 pin-project-lite = { version = "0.2", optional = true }
 
 # Error control, tracing, config
-thiserror = "1.0"
+thiserror = "1"
 htsget-config = { version = "0.9.0", path = "../htsget-config", default-features = false }
 htsget-test = { version = "0.6.0", path = "../htsget-test", features = ["http"], default-features = false }
 tracing = "0.1"
-base64 = "0.21"
-serde = "1.0"
+base64 = "0.22"
+serde = "1"
 
 [dev-dependencies]
-tempfile = "3.6"
+tempfile = "3"
 data-url = "0.3"
 
 # Axum server
-reqwest = { version = "0.11", default-features = false, features = ["rustls-tls"] }
+reqwest = { version = "0.12", default-features = false, features = ["rustls-tls"] }
 
 criterion = { version = "0.5", features = ["async_tokio"] }
 
diff --git a/htsget-search/src/htsget/bam_search.rs b/htsget-search/src/htsget/bam_search.rs
index 7aa17c65a..56afc1393 100644
--- a/htsget-search/src/htsget/bam_search.rs
+++ b/htsget-search/src/htsget/bam_search.rs
@@ -64,12 +64,12 @@ where
       .with_class(Body)])
   }
 
-  async fn read_bytes(_header: &Header, reader: &mut AsyncReader<ReaderType>) -> Option<usize> {
+  async fn read_bytes(reader: &mut AsyncReader<ReaderType>) -> Option<usize> {
     reader.read_record(&mut Default::default()).await.ok()
   }
 
   fn virtual_position(&self, reader: &AsyncReader<ReaderType>) -> VirtualPosition {
-    reader.virtual_position()
+    reader.get_ref().virtual_position()
   }
 }
 
diff --git a/htsget-search/src/htsget/bcf_search.rs b/htsget-search/src/htsget/bcf_search.rs
index 545e5a7f3..8017563bc 100644
--- a/htsget-search/src/htsget/bcf_search.rs
+++ b/htsget-search/src/htsget/bcf_search.rs
@@ -17,7 +17,6 @@ use tokio::io::AsyncRead;
 use tracing::{instrument, trace};
 
 use crate::htsget::search::{find_first, BgzfSearch, Search};
-use crate::htsget::ParsedHeader;
 use crate::storage::{BytesPosition, Storage};
 use crate::{Format, Query, Result};
 
@@ -35,12 +34,12 @@ where
   S: Storage<Streamable = ReaderType> + Send + Sync + 'static,
   ReaderType: AsyncRead + Unpin + Send + Sync,
 {
-  async fn read_bytes(_header: &Header, reader: &mut AsyncReader<ReaderType>) -> Option<usize> {
-    reader.read_lazy_record(&mut Default::default()).await.ok()
+  async fn read_bytes(reader: &mut AsyncReader<ReaderType>) -> Option<usize> {
+    reader.read_record(&mut Default::default()).await.ok()
   }
 
   fn virtual_position(&self, reader: &AsyncReader<ReaderType>) -> VirtualPosition {
-    reader.virtual_position()
+    reader.get_ref().virtual_position()
   }
 }
 
@@ -57,15 +56,7 @@ where
   }
 
   async fn read_header(reader: &mut AsyncReader<ReaderType>) -> io::Result<Header> {
-    reader.read_file_format().await?;
-
-    Ok(
-      reader
-        .read_header()
-        .await?
-        .parse::<ParsedHeader<Header>>()?
-        .into_inner(),
-    )
+    reader.read_header().await
   }
 
   async fn read_index_inner<T: AsyncRead + Unpin + Send>(inner: T) -> io::Result<Index> {
diff --git a/htsget-search/src/htsget/cram_search.rs b/htsget-search/src/htsget/cram_search.rs
index 49fa286fc..32a9bde7c 100644
--- a/htsget-search/src/htsget/cram_search.rs
+++ b/htsget-search/src/htsget/cram_search.rs
@@ -72,7 +72,6 @@ where
   async fn get_byte_ranges_for_header(
     &self,
     index: &Index,
-    _header: &Header,
     _reader: &mut AsyncReader<ReaderType>,
     _query: &Query,
   ) -> Result<BytesPosition> {
diff --git a/htsget-search/src/htsget/search.rs b/htsget-search/src/htsget/search.rs
index 88fc56d9a..b93a38465 100644
--- a/htsget-search/src/htsget/search.rs
+++ b/htsget-search/src/htsget/search.rs
@@ -82,7 +82,6 @@ where
   async fn get_byte_ranges_for_header(
     &self,
     index: &Index,
-    header: &Header,
     reader: &mut Reader,
     query: &Query,
   ) -> Result<BytesPosition>;
@@ -265,7 +264,7 @@ where
 
             byte_ranges.push(
               self
-                .get_byte_ranges_for_header(&index, &header, &mut reader, &query)
+                .get_byte_ranges_for_header(&index, &mut reader, &query)
                 .await?,
             );
 
@@ -293,10 +292,10 @@ where
         let index = self.read_index(&query).await?;
 
         let header_end = self.get_header_end_offset(&index).await?;
-        let (header, mut reader) = self.get_header(&query, header_end).await?;
+        let (_, mut reader) = self.get_header(&query, header_end).await?;
 
         let header_byte_ranges = self
-          .get_byte_ranges_for_header(&index, &header, &mut reader, &query)
+          .get_byte_ranges_for_header(&index, &mut reader, &query)
           .await?;
 
         self
@@ -548,7 +547,7 @@ where
   }
 
   /// Get the virtual position of the underlying reader.
-  async fn read_bytes(header: &Header, reader: &mut Reader) -> Option<usize>;
+  async fn read_bytes(reader: &mut Reader) -> Option<usize>;
 
   /// Get the virtual position of the underlying reader.
   fn virtual_position(&self, reader: &Reader) -> VirtualPosition;
@@ -593,7 +592,6 @@ where
   async fn get_byte_ranges_for_header(
     &self,
     index: &Index<I>,
-    header: &Header,
     reader: &mut Reader,
     query: &Query,
   ) -> Result<BytesPosition> {
@@ -603,7 +601,7 @@ where
       current_block_index.compressed()
     } else {
       loop {
-        let bytes_read = Self::read_bytes(header, reader).await.unwrap_or_default();
+        let bytes_read = Self::read_bytes(reader).await.unwrap_or_default();
         let actual_block_index = self.virtual_position(reader).compressed();
 
         if bytes_read == 0 || actual_block_index > current_block_index.compressed() {
diff --git a/htsget-search/src/htsget/vcf_search.rs b/htsget-search/src/htsget/vcf_search.rs
index 08a391a6a..db4acfe35 100644
--- a/htsget-search/src/htsget/vcf_search.rs
+++ b/htsget-search/src/htsget/vcf_search.rs
@@ -38,15 +38,12 @@ where
   S: Storage<Streamable = ReaderType> + Send + Sync + 'static,
   ReaderType: AsyncRead + Unpin + Send + Sync,
 {
-  async fn read_bytes(header: &Header, reader: &mut AsyncReader<ReaderType>) -> Option<usize> {
-    reader
-      .read_record(header, &mut Default::default())
-      .await
-      .ok()
+  async fn read_bytes(reader: &mut AsyncReader<ReaderType>) -> Option<usize> {
+    reader.read_record(&mut Default::default()).await.ok()
   }
 
   fn virtual_position(&self, reader: &AsyncReader<ReaderType>) -> VirtualPosition {
-    reader.virtual_position()
+    reader.get_ref().virtual_position()
   }
 }
 
diff --git a/htsget-search/src/storage/data_server.rs b/htsget-search/src/storage/data_server.rs
index 03192dabb..43cd31e47 100644
--- a/htsget-search/src/storage/data_server.rs
+++ b/htsget-search/src/storage/data_server.rs
@@ -4,21 +4,22 @@
 //! This is the code that replies to the url tickets generated by [HtsGet], in the case of [LocalStorage].
 //!
 
+use axum::extract::Request;
 use std::net::{AddrParseError, SocketAddr};
 use std::path::Path;
-use std::pin::Pin;
 use std::sync::Arc;
 
 use axum::Router;
-use futures_util::future::poll_fn;
-use hyper::server::accept::Accept;
-use hyper::server::conn::{AddrIncoming, Http};
+use hyper::body::Incoming;
+use hyper::service::service_fn;
+use hyper_util::rt::{TokioExecutor, TokioIo};
+use hyper_util::server::conn::auto::Builder;
 use tokio::net::TcpListener;
 use tokio_rustls::TlsAcceptor;
-use tower::MakeService;
+use tower::Service;
 use tower_http::services::ServeDir;
 use tower_http::trace::TraceLayer;
-use tracing::instrument;
+use tracing::{error, instrument, warn};
 use tracing::{info, trace};
 
 use htsget_config::config::cors::CorsConfig;
@@ -85,7 +86,7 @@ impl BindDataServer {
       self.cors.clone(),
     )
     .await?;
-    self.addr = server.local_addr();
+    self.addr = server.local_addr()?;
     Ok(server)
   }
 
@@ -119,7 +120,7 @@ impl From<AddrParseError> for StorageError {
 /// The local storage static http server.
 #[derive(Debug)]
 pub struct DataServer {
-  listener: AddrIncoming,
+  listener: TcpListener,
   serve_at: String,
   cert_key_pair: Option<TlsServerConfig>,
   cors: CorsConfig,
@@ -137,7 +138,6 @@ impl DataServer {
     let listener = TcpListener::bind(addr)
       .await
       .map_err(|err| IoError("binding data server addr".to_string(), err))?;
-    let listener = AddrIncoming::from_listener(listener)?;
 
     info!(address = ?listener.local_addr(), "data server address bound to");
     Ok(Self {
@@ -150,38 +150,42 @@ impl DataServer {
 
   /// Run the actual server, using the provided path, key and certificate.
   #[instrument(level = "trace", skip_all)]
-  pub async fn serve<P: AsRef<Path>>(mut self, path: P) -> Result<()> {
-    let mut app = Router::new()
+  pub async fn serve<P: AsRef<Path>>(self, path: P) -> Result<()> {
+    let app = Router::new()
       .nest_service(&self.serve_at, ServeDir::new(path))
       .layer(configure_cors(self.cors)?)
-      .layer(TraceLayer::new_for_http())
-      .into_make_service_with_connect_info::<SocketAddr>();
+      .layer(TraceLayer::new_for_http());
 
-    // TODO write using new axum functions.
     match self.cert_key_pair {
-      None => axum::Server::builder(self.listener)
-        .serve(app)
+      None => axum::serve(self.listener, app)
         .await
         .map_err(|err| ServerError(err.to_string())),
       Some(tls) => {
-        let acceptor = TlsAcceptor::from(Arc::new(tls.into_inner()));
+        let tls_acceptor = TlsAcceptor::from(Arc::new(tls.into_inner()));
 
         loop {
-          let stream = poll_fn(|cx| Pin::new(&mut self.listener).poll_accept(cx))
-            .await
-            .ok_or_else(|| ServerError("poll accept failed".to_string()))?
-            .map_err(|err| ServerError(err.to_string()))?;
-          let acceptor = acceptor.clone();
-
-          let app = app
-            .make_service(&stream)
-            .await
-            .map_err(|err| ServerError(err.to_string()))?;
-
-          trace!(stream = ?stream, "accepting stream");
+          let tower_service = app.clone();
+          let tls_acceptor = tls_acceptor.clone();
+
+          trace!("accepting connection");
+          let (cnx, addr) = self.listener.accept().await.unwrap();
+
           tokio::spawn(async move {
-            if let Ok(stream) = acceptor.accept(stream).await {
-              let _ = Http::new().serve_connection(stream, app).await;
+            let Ok(stream) = tls_acceptor.accept(cnx).await else {
+              error!("error during tls handshake connection from {}", addr);
+              return;
+            };
+
+            let stream = TokioIo::new(stream);
+            let hyper_service =
+              service_fn(move |request: Request<Incoming>| tower_service.clone().call(request));
+
+            let ret = Builder::new(TokioExecutor::new())
+              .serve_connection_with_upgrades(stream, hyper_service)
+              .await;
+
+            if let Err(err) = ret {
+              warn!("error serving connection from {}: {}", addr, err);
             }
           });
         }
@@ -190,8 +194,8 @@ impl DataServer {
   }
 
   /// Get the local address the server has bound to.
-  pub fn local_addr(&self) -> SocketAddr {
-    self.listener.local_addr()
+  pub fn local_addr(&self) -> Result<SocketAddr> {
+    Ok(self.listener.local_addr()?)
   }
 }
 
@@ -356,7 +360,7 @@ mod tests {
       "/data".to_string(),
     );
     let server = formatter.bind_data_server().await.unwrap();
-    assert_eq!(formatter.get_addr(), server.local_addr());
+    assert_eq!(formatter.get_addr(), server.local_addr().unwrap());
   }
 
   #[tokio::test]
@@ -406,7 +410,7 @@ mod tests {
     let server = DataServer::bind_addr(addr, "/data", cert_key_pair, default_cors_config())
       .await
       .unwrap();
-    let port = server.local_addr().port();
+    let port = server.local_addr().unwrap().port();
     tokio::spawn(async move { server.serve(path).await.unwrap() });
 
     port
diff --git a/htsget-search/src/storage/mod.rs b/htsget-search/src/storage/mod.rs
index 812061481..d4e0e5d51 100644
--- a/htsget-search/src/storage/mod.rs
+++ b/htsget-search/src/storage/mod.rs
@@ -1,5 +1,6 @@
 //! Module providing the abstractions needed to read files from an storage
 //!
+
 use std::cmp::Ordering;
 use std::fmt::{Debug, Display, Formatter};
 use std::io;
@@ -199,6 +200,12 @@ impl From<StorageError> for io::Error {
   }
 }
 
+impl From<io::Error> for StorageError {
+  fn from(error: io::Error) -> Self {
+    Self::IoError("io error".to_string(), error)
+  }
+}
+
 /// A DataBlock is either a range of bytes, or a data blob that gets transformed into a data uri.
 #[derive(Debug, PartialEq, Eq)]
 pub enum DataBlock {
diff --git a/htsget-search/src/storage/s3.rs b/htsget-search/src/storage/s3.rs
index a2bb89414..67ced38b1 100644
--- a/htsget-search/src/storage/s3.rs
+++ b/htsget-search/src/storage/s3.rs
@@ -4,25 +4,29 @@
 use std::fmt::Debug;
 use std::io;
 use std::io::ErrorKind::Other;
+use std::pin::Pin;
+use std::task::{Context, Poll};
 use std::time::Duration;
 
 use async_trait::async_trait;
+use aws_config::BehaviorVersion;
 use aws_sdk_s3::error::{DisplayErrorContext, SdkError};
 use aws_sdk_s3::operation::get_object::builders::GetObjectFluentBuilder;
 use aws_sdk_s3::operation::get_object::GetObjectError;
 use aws_sdk_s3::operation::head_object::{HeadObjectError, HeadObjectOutput};
 use aws_sdk_s3::presigning::PresigningConfig;
-use aws_sdk_s3::primitives::{ByteStream, SdkBody};
+use aws_sdk_s3::primitives::ByteStream;
 use aws_sdk_s3::types::StorageClass;
 use aws_sdk_s3::Client;
 use bytes::Bytes;
-use http::Response;
+use futures::Stream;
+use pin_project_lite::pin_project;
 use tokio_util::io::StreamReader;
 use tracing::instrument;
 use tracing::{debug, warn};
 
 use crate::storage::s3::Retrieval::{Delayed, Immediate};
-use crate::storage::StorageError::{AwsS3Error, KeyNotFound};
+use crate::storage::StorageError::{AwsS3Error, IoError, KeyNotFound};
 use crate::storage::{BytesPosition, HeadOptions, StorageError};
 use crate::storage::{BytesRange, Storage};
 use crate::Url;
@@ -58,7 +62,7 @@ impl S3Storage {
     endpoint: Option<String>,
     path_style: bool,
   ) -> Self {
-    let sdk_config = aws_config::load_from_env().await;
+    let sdk_config = aws_config::load_defaults(BehaviorVersion::latest()).await;
     let mut s3_config_builder = aws_sdk_s3::config::Builder::from(&sdk_config);
     s3_config_builder.set_endpoint_url(endpoint); // For local S3 storage, i.e: Minio
     s3_config_builder.set_force_path_style(Some(path_style));
@@ -189,14 +193,16 @@ impl S3Storage {
     &self,
     key: K,
     options: GetOptions<'_>,
-  ) -> Result<StreamReader<ByteStream, Bytes>> {
-    let response = self.get_content(key, options).await?;
-    Ok(StreamReader::new(response))
+  ) -> Result<StreamReader<S3Stream, Bytes>> {
+    Ok(StreamReader::new(S3Stream::new(
+      self.get_content(key, options).await?,
+    )))
   }
 
-  fn map_get_error<K>(key: K, error: SdkError<GetObjectError, Response<SdkBody>>) -> StorageError
+  fn map_get_error<K, T>(key: K, error: SdkError<GetObjectError, T>) -> StorageError
   where
     K: AsRef<str> + Send,
+    T: Debug + Send + Sync + 'static,
   {
     warn!("S3 error: {}", DisplayErrorContext(&error));
 
@@ -209,9 +215,36 @@ impl S3Storage {
   }
 }
 
+pin_project! {
+  /// A wrapper around a `ByteStream` in order to implement `Stream`.
+  pub struct S3Stream {
+    #[pin]
+    inner: ByteStream
+  }
+}
+
+impl S3Stream {
+  /// Create a new S3Stream.
+  pub fn new(inner: ByteStream) -> Self {
+    S3Stream { inner }
+  }
+}
+
+impl Stream for S3Stream {
+  type Item = Result<Bytes>;
+
+  fn poll_next(self: Pin<&mut Self>, cx: &mut Context<'_>) -> Poll<Option<Self::Item>> {
+    self
+      .project()
+      .inner
+      .poll_next(cx)
+      .map_err(|err| IoError("io error".to_string(), err.into()))
+  }
+}
+
 #[async_trait]
 impl Storage for S3Storage {
-  type Streamable = StreamReader<ByteStream, Bytes>;
+  type Streamable = StreamReader<S3Stream, Bytes>;
 
   /// Gets the actual s3 object as a buffered reader.
   #[instrument(level = "trace", skip(self))]
@@ -252,8 +285,13 @@ impl Storage for S3Storage {
     let key = key.as_ref();
 
     let head = self.s3_head(key).await?;
-    let len = u64::try_from(head.content_length).map_err(|err| {
-      StorageError::IoError(
+
+    let content_length = head
+      .content_length()
+      .ok_or_else(|| AwsS3Error("unknown content length".to_string(), key.to_string()))?;
+
+    let len = u64::try_from(content_length).map_err(|err| {
+      IoError(
         "failed to convert file length to `u64`".to_string(),
         io::Error::new(Other, err),
       )
diff --git a/htsget-search/src/storage/url.rs b/htsget-search/src/storage/url.rs
index 2ac418cba..6de59c807 100644
--- a/htsget-search/src/storage/url.rs
+++ b/htsget-search/src/storage/url.rs
@@ -260,17 +260,18 @@ impl Storage for UrlStorage {
 #[cfg(test)]
 mod tests {
   use std::future::Future;
-  use std::net::TcpListener;
   use std::path::Path;
   use std::str::FromStr;
   use std::{result, vec};
 
+  use axum::body::Body;
   use axum::middleware::Next;
   use axum::response::Response;
   use axum::{middleware, Router};
   use http::header::{AUTHORIZATION, HOST};
   use http::{HeaderName, HeaderValue, Request, StatusCode};
   use tokio::io::AsyncReadExt;
+  use tokio::net::TcpListener;
   use tower_http::services::ServeDir;
 
   use htsget_config::types::Headers;
@@ -594,10 +595,7 @@ mod tests {
     with_test_server(base_path.path(), test).await;
   }
 
-  async fn test_auth<B>(
-    request: Request<B>,
-    next: Next<B>,
-  ) -> result::Result<Response, StatusCode> {
+  async fn test_auth(request: Request<Body>, next: Next) -> result::Result<Response, StatusCode> {
     let auth_header = request
       .headers()
       .get(AUTHORIZATION)
@@ -619,14 +617,10 @@ mod tests {
       .route_layer(middleware::from_fn(test_auth));
 
     // TODO fix this in htsget-test to bind and return tcp listener.
-    let listener = TcpListener::bind("127.0.0.1:0").unwrap();
+    let listener = TcpListener::bind("127.0.0.1:0").await.unwrap();
     let addr = listener.local_addr().unwrap();
 
-    tokio::spawn(
-      axum::Server::from_tcp(listener)
-        .unwrap()
-        .serve(router.into_make_service()),
-    );
+    tokio::spawn(async move { axum::serve(listener, router.into_make_service()).await });
 
     test(format!("http://{}", addr)).await;
   }
diff --git a/htsget-test/Cargo.toml b/htsget-test/Cargo.toml
index 22a0b3ae0..73c2f0236 100644
--- a/htsget-test/Cargo.toml
+++ b/htsget-test/Cargo.toml
@@ -2,7 +2,7 @@
 name = "htsget-test"
 version = "0.6.0"
 rust-version = "1.74"
-authors = ["Marko Malenic <mmalenic1@gmail.com>"]
+authors = ["Marko Malenic <mmalenic1@gmail.com>", "Roman Valls Guimera <brainstorm@nopcode.org>"]
 edition = "2021"
 license = "MIT"
 description = "Common test functions and utilities used by htsget-rs."
@@ -42,26 +42,26 @@ default = []
 # Server tests dependencies
 htsget-config = { version = "0.9.0", path = "../htsget-config", default-features = false, optional = true }
 
-noodles = { version = "0.65", optional = true, features = ["async", "bgzf", "vcf", "cram", "bcf", "bam", "fasta"] }
+noodles = { version = "0.74", optional = true, features = ["async", "bgzf", "vcf", "cram", "bcf", "bam", "fasta"] }
 
-reqwest = { version = "0.11", default-features = false, features = ["json", "rustls-tls"], optional = true }
+reqwest = { version = "0.12", default-features = false, features = ["json", "rustls-tls"], optional = true }
 tokio = { version = "1", features = ["rt-multi-thread", "fs"], optional = true }
 futures = { version = "0.3", optional = true }
 async-trait = { version = "0.1", optional = true }
-http = { version = "0.2", optional = true }
+http = { version = "1", optional = true }
 mime = { version = "0.3", optional = true }
-serde_json = { version = "1.0", features = ["preserve_order"], optional = true }
+serde_json = { version = "1", features = ["preserve_order"], optional = true }
 serde = { version = "1", optional = true }
-base64 = { version = "0.21", optional = true }
+base64 = { version = "0.22", optional = true }
 
-tempfile = { version = "3.3", optional = true }
-aws-sdk-s3 = { version = "0.34", features = ["test-util"], optional = true }
-aws-config = { version = "0.56", optional = true }
-aws-credential-types = { version = "0.56", features = ["test-util"], optional = true }
-s3s = { version = "0.8", optional = true }
-s3s-fs = { version = "0.8", optional = true }
-s3s-aws = { version = "0.8", optional = true }
+tempfile = { version = "3", optional = true }
+aws-sdk-s3 = { version = "1", features = ["test-util"], optional = true }
+aws-config = { version = "1", optional = true }
+aws-credential-types = { version = "1", features = ["test-util"], optional = true }
+s3s = { version = "0.10", optional = true }
+s3s-fs = { version = "0.10", optional = true }
+s3s-aws = { version = "0.10", optional = true }
 
 # Default dependencies
-rcgen = "0.12"
-thiserror = "1.0"
+rcgen = "0.13"
+thiserror = "1"
diff --git a/htsget-test/src/aws_mocks.rs b/htsget-test/src/aws_mocks.rs
index 38d5cda53..a70a0cc18 100644
--- a/htsget-test/src/aws_mocks.rs
+++ b/htsget-test/src/aws_mocks.rs
@@ -1,7 +1,7 @@
 use aws_config::SdkConfig;
 use aws_credential_types::provider::SharedCredentialsProvider;
 use aws_credential_types::Credentials;
-use aws_sdk_s3::config::Region;
+use aws_sdk_s3::config::{BehaviorVersion, Region};
 use aws_sdk_s3::Client;
 use s3s::auth::SimpleAuth;
 use s3s::service::S3ServiceBuilder;
@@ -27,7 +27,7 @@ pub async fn run_s3_test_server<F, Fut>(
 {
   let cred = Credentials::for_tests();
 
-  let conn = {
+  let client = {
     let fs = FileSystem::new(server_base_path).unwrap();
 
     let auth = SimpleAuth::from_single(cred.access_key_id(), cred.secret_access_key());
@@ -36,14 +36,15 @@ pub async fn run_s3_test_server<F, Fut>(
     service.set_auth(auth);
     service.set_base_domain(domain_name);
 
-    s3s_aws::Connector::from(service.build().into_shared())
+    s3s_aws::Client::from(service.build().into_shared())
   };
 
   let sdk_config = SdkConfig::builder()
     .credentials_provider(SharedCredentialsProvider::new(cred))
-    .http_connector(conn)
+    .http_client(client)
     .region(Region::new(region))
     .endpoint_url(format!("http://{domain_name}"))
+    .behavior_version(BehaviorVersion::latest())
     .build();
 
   test(Client::new(&sdk_config), server_base_path.to_path_buf()).await;
diff --git a/htsget-test/src/http/concat.rs b/htsget-test/src/http/concat.rs
index c6e900e22..77c7eb65c 100644
--- a/htsget-test/src/http/concat.rs
+++ b/htsget-test/src/http/concat.rs
@@ -216,19 +216,15 @@ impl ReadRecords {
         let mut reader =
           vcf::AsyncReader::new(bgzf::AsyncReader::new(self.merged_bytes.as_slice()));
         let header = reader.read_header().await.map_err(TestError::read_record)?;
-        println!("{header}");
+        println!("{:#?}", header);
 
-        self.iterate_records(reader.records(&header)).await
+        self.iterate_records(reader.records()).await
       }
       Format::Bcf => {
         let mut reader = bcf::AsyncReader::new(self.merged_bytes.as_slice());
-        reader
-          .read_file_format()
-          .await
-          .map_err(TestError::read_record)?;
         reader.read_header().await.map_err(TestError::read_record)?;
 
-        self.iterate_records(reader.lazy_records()).await
+        self.iterate_records(reader.records()).await
       }
     }
   }
diff --git a/htsget-test/src/util.rs b/htsget-test/src/util.rs
index 2aec3bce0..50ffd5ac8 100644
--- a/htsget-test/src/util.rs
+++ b/htsget-test/src/util.rs
@@ -12,8 +12,8 @@ pub fn generate_test_certificates<P: AsRef<Path>>(
   let cert_path = in_path.as_ref().join(cert_name);
 
   let cert = generate_simple_self_signed(vec!["localhost".to_string()]).unwrap();
-  fs::write(&key_path, cert.serialize_private_key_pem()).unwrap();
-  fs::write(&cert_path, cert.serialize_pem().unwrap()).unwrap();
+  fs::write(&key_path, cert.key_pair.serialize_pem()).unwrap();
+  fs::write(&cert_path, cert.cert.pem()).unwrap();
 
   (key_path, cert_path)
 }