diff --git a/easybuild/easyconfigs/r/RDKit/RDKit-2021.03.4-foss-2021a.eb b/easybuild/easyconfigs/r/RDKit/RDKit-2021.03.4-foss-2021a.eb
index 3146628e323..3803d09ed7f 100644
--- a/easybuild/easyconfigs/r/RDKit/RDKit-2021.03.4-foss-2021a.eb
+++ b/easybuild/easyconfigs/r/RDKit/RDKit-2021.03.4-foss-2021a.eb
@@ -20,7 +20,7 @@ patches = [
 checksums = [
     'bed309df7f1e2ea25736a986cf951325681142ee49468b1c62d020a109d2ef52',  # Release_2021_03_4.tar.gz
     '45869e01461b66e42c9305f5e8a65f696417e4777c2da60ef81d1e26e57d1b2e',  # RDKit-2021.03.4_skip-broken-test.patch
-    '64d2c588203998c1da028b95032a7c006834e957f10c6335bb534148c0517dcb',  # RDKit-2021.03.4_fix-comic-neue-checksum.patch
+    'a13ede07f2082b73348c4ecdd4528b5f758bc064e80fa4d0aa108ebcb0ea28e9',  # RDKit-2021.03.4_fix-comic-neue-checksum.patch
 ]
 
 # Dependencies varies from version to version
diff --git a/easybuild/easyconfigs/r/RDKit/RDKit-2021.03.4_fix-comic-neue-checksum.patch b/easybuild/easyconfigs/r/RDKit/RDKit-2021.03.4_fix-comic-neue-checksum.patch
index 3316f1a811c..6d7b417054d 100644
--- a/easybuild/easyconfigs/r/RDKit/RDKit-2021.03.4_fix-comic-neue-checksum.patch
+++ b/easybuild/easyconfigs/r/RDKit/RDKit-2021.03.4_fix-comic-neue-checksum.patch
@@ -11,7 +11,7 @@ Author: Robin Engler, SIB Swiss Institute for Bioinformatics
    endif()
    if(needDownload)
 -    set(MD5Sum "23ed3f833c1ae0adb141a26b4a30d73e")
-+    set(MD5Sum "850b0df852f1cda4970887b540f8f333")
++    set(MD5Sum "b7fd0df73ad4637504432d72a0accb8f")
      downloadAndCheckMD5("https://fonts.google.com/download?family=Comic%20Neue"
            "${CMAKE_CURRENT_SOURCE_DIR}/Comic_Neue.zip"
            ${MD5Sum})
diff --git a/easybuild/easyconfigs/r/RDKit/RDKit-2023.03.3-foss-2021a.eb b/easybuild/easyconfigs/r/RDKit/RDKit-2023.03.3-foss-2021a.eb
index c9222722632..11ced01d234 100644
--- a/easybuild/easyconfigs/r/RDKit/RDKit-2023.03.3-foss-2021a.eb
+++ b/easybuild/easyconfigs/r/RDKit/RDKit-2023.03.3-foss-2021a.eb
@@ -15,10 +15,12 @@ source_urls = ['https://github.com/rdkit/rdkit/archive/']
 sources = ['Release_%s.tar.gz' % version.replace('.', '_')]
 patches = [
     'RDKit-2021.03.4_skip-broken-test.patch',
+    'RDKit-2023.03.3_fix-comic-neue-checksum.patch',
 ]
 checksums = [
     {'Release_2023_03_3.tar.gz': 'bdbf9a2e6988526bfeb8c56ce3cdfe2998d60ac289078e2215374288185e8c8d'},
     {'RDKit-2021.03.4_skip-broken-test.patch': '45869e01461b66e42c9305f5e8a65f696417e4777c2da60ef81d1e26e57d1b2e'},
+    {'RDKit-2023.03.3_fix-comic-neue-checksum.patch': '93ae766b6224385ed30e3cea2a6af9a6d8fdf9a647e313c7c66dfc2b46c0e5a5'},
 ]
 
 # Dependencies varies from version to version
diff --git a/easybuild/easyconfigs/r/RDKit/RDKit-2023.03.3_fix-comic-neue-checksum.patch b/easybuild/easyconfigs/r/RDKit/RDKit-2023.03.3_fix-comic-neue-checksum.patch
new file mode 100644
index 00000000000..d11d9c52a51
--- /dev/null
+++ b/easybuild/easyconfigs/r/RDKit/RDKit-2023.03.3_fix-comic-neue-checksum.patch
@@ -0,0 +1,11 @@
+--- rdkit-Release_2023_03_3/Code/GraphMol/MolDraw2D/CMakeLists.txt.ori	2024-02-22 11:04:12.288903006 +0100
++++ rdkit-Release_2023_03_3/Code/GraphMol/MolDraw2D/CMakeLists.txt	2024-02-22 11:04:44.679470021 +0100
+@@ -17,7 +17,7 @@
+     set(needDownload "FALSE")
+   endif()
+   if(needDownload)
+-    set(MD5Sum "850b0df852f1cda4970887b540f8f333")
++    set(MD5Sum "b7fd0df73ad4637504432d72a0accb8f")
+     downloadAndCheckMD5("https://fonts.google.com/download?family=Comic%20Neue"
+           "${CMAKE_CURRENT_SOURCE_DIR}/Comic_Neue.zip"
+           ${MD5Sum})