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trying to locate phASER_GTEx_v8_merged.vcf.gz for phaser_cis_var.py (phaser-pop) #77

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7ehuang opened this issue Oct 26, 2022 · 0 comments

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@7ehuang
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7ehuang commented Oct 26, 2022

Hi,
I'm trying to run phaser pop example using the provided files, Whole_Blood.sample_map.txt and Whole_Blood.test_pairs.txt. I was able to download phASER_WASP_GTEx_v8_matrix.gw_phased.txt.gz from the GTEx website, but I'm having trouble locating the read-backed VCF file (phASER_GTEx_v8_merged.vcf.gz) despite having dbGAP access to phs000424. Is there a specific accession ID or version of phs000424 that I need to access to find the file?

Additionally, from my understanding, the phased vcf file only affects the results reported in columns 23-26 of the phaser_cis_var.py output (var_het_ref_counts, var_het_alt_counts, var_hom_hap1_counts, var_hom_hap2_counts) since the aFC-related measures in the other columns are calculated per variant rather than across all variants in the haplotype. Is this correct?

Thank you so much!

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