diff --git a/rules-tests/TypeDeclaration/Rector/BooleanAnd/BinaryOpNullableToInstanceofRector/Fixture/skip_assign.php.inc b/rules-tests/TypeDeclaration/Rector/BooleanAnd/BinaryOpNullableToInstanceofRector/Fixture/skip_assign.php.inc
new file mode 100644
index 00000000000..4da84c219e9
--- /dev/null
+++ b/rules-tests/TypeDeclaration/Rector/BooleanAnd/BinaryOpNullableToInstanceofRector/Fixture/skip_assign.php.inc
@@ -0,0 +1,24 @@
+<?php
+
+namespace Rector\Tests\TypeDeclaration\Rector\BooleanAnd\BinaryOpNullableToInstanceofRector\Fixture;
+
+use Rector\Tests\TypeDeclaration\Rector\BooleanAnd\BinaryOpNullableToInstanceofRector\Source\SomeInstance;
+
+final class SkipAssign
+{
+    private ?SomeInstance $someClass;
+
+    public function run()
+    {
+        if (($this->someClass = $this->get()) && $this->someClass->someMethod()) {
+            return $this->someClass->someMethod();
+        }
+
+        return 'no';
+    }
+
+    private function get(): ?SomeInstance
+    {
+        return rand(0, 1) ? new SomeInstance() : null;
+    }
+}
diff --git a/rules-tests/TypeDeclaration/Rector/BooleanAnd/BinaryOpNullableToInstanceofRector/Fixture/skip_assign2.php.inc b/rules-tests/TypeDeclaration/Rector/BooleanAnd/BinaryOpNullableToInstanceofRector/Fixture/skip_assign2.php.inc
new file mode 100644
index 00000000000..c835f01f4fc
--- /dev/null
+++ b/rules-tests/TypeDeclaration/Rector/BooleanAnd/BinaryOpNullableToInstanceofRector/Fixture/skip_assign2.php.inc
@@ -0,0 +1,24 @@
+<?php
+
+namespace Rector\Tests\TypeDeclaration\Rector\BooleanAnd\BinaryOpNullableToInstanceofRector\Fixture;
+
+use Rector\Tests\TypeDeclaration\Rector\BooleanAnd\BinaryOpNullableToInstanceofRector\Source\SomeInstance;
+
+final class SkipAssign2
+{
+    private ?SomeInstance $someClass;
+
+    public function run(bool $a)
+    {
+        if ($a === true && ($this->someClass = $this->get()) && $this->someClass->someMethod()) {
+            return $this->someClass->someMethod();
+        }
+
+        return 'no';
+    }
+
+    private function get(): ?SomeInstance
+    {
+        return rand(0, 1) ? new SomeInstance() : null;
+    }
+}
diff --git a/rules/TypeDeclaration/Rector/BooleanAnd/BinaryOpNullableToInstanceofRector.php b/rules/TypeDeclaration/Rector/BooleanAnd/BinaryOpNullableToInstanceofRector.php
index 15aafcaab3a..dd5acd94813 100644
--- a/rules/TypeDeclaration/Rector/BooleanAnd/BinaryOpNullableToInstanceofRector.php
+++ b/rules/TypeDeclaration/Rector/BooleanAnd/BinaryOpNullableToInstanceofRector.php
@@ -6,6 +6,7 @@
 
 use PhpParser\Node;
 use PhpParser\Node\Expr;
+use PhpParser\Node\Expr\Assign;
 use PhpParser\Node\Expr\BinaryOp\BooleanAnd;
 use PhpParser\Node\Expr\BinaryOp\BooleanOr;
 use PhpParser\Node\Expr\BooleanNot;
@@ -70,6 +71,10 @@ public function getNodeTypes(): array
      */
     public function refactor(Node $node): ?Node
     {
+        if ($node->left instanceof Assign || $node->right instanceof Assign) {
+            return null;
+        }
+
         if ($node instanceof BooleanOr) {
             return $this->processNegationBooleanOr($node);
         }