diff --git a/main/_images/sec_catalog_anapla_models_mallardblackduck_2l19.png b/main/_images/sec_catalog_anapla_models_mallardblackduck_2l19.png index 4aa7943..2dc7927 100644 Binary files a/main/_images/sec_catalog_anapla_models_mallardblackduck_2l19.png and b/main/_images/sec_catalog_anapla_models_mallardblackduck_2l19.png differ diff --git a/main/_images/sec_catalog_homsap_models_americanadmixture_4b11.png b/main/_images/sec_catalog_homsap_models_americanadmixture_4b11.png deleted file mode 100644 index 99e4bc3..0000000 Binary files a/main/_images/sec_catalog_homsap_models_americanadmixture_4b11.png and /dev/null differ diff --git a/main/_images/sec_catalog_homsap_models_americanadmixture_4b18.png b/main/_images/sec_catalog_homsap_models_americanadmixture_4b18.png new file mode 100644 index 0000000..388845d Binary files /dev/null and b/main/_images/sec_catalog_homsap_models_americanadmixture_4b18.png differ diff --git a/main/_images/sec_catalog_homsap_models_outofafrica_2t12.png b/main/_images/sec_catalog_homsap_models_outofafrica_2t12.png index 7ef1271..00cb202 100644 Binary files a/main/_images/sec_catalog_homsap_models_outofafrica_2t12.png and b/main/_images/sec_catalog_homsap_models_outofafrica_2t12.png differ diff --git a/main/_images/sec_catalog_homsap_models_outofafrica_3g09.png b/main/_images/sec_catalog_homsap_models_outofafrica_3g09.png index 7f26bb7..04cdc0c 100644 Binary files a/main/_images/sec_catalog_homsap_models_outofafrica_3g09.png and b/main/_images/sec_catalog_homsap_models_outofafrica_3g09.png differ diff --git a/main/_images/sec_catalog_homsap_models_outofafrica_4j17.png b/main/_images/sec_catalog_homsap_models_outofafrica_4j17.png index a4ff7f1..7ad5266 100644 Binary files a/main/_images/sec_catalog_homsap_models_outofafrica_4j17.png and b/main/_images/sec_catalog_homsap_models_outofafrica_4j17.png differ diff --git a/main/_images/sec_catalog_homsap_models_outofafricaarchaicadmixture_5r19.png b/main/_images/sec_catalog_homsap_models_outofafricaarchaicadmixture_5r19.png index a40d3e6..44c378f 100644 Binary files a/main/_images/sec_catalog_homsap_models_outofafricaarchaicadmixture_5r19.png and b/main/_images/sec_catalog_homsap_models_outofafricaarchaicadmixture_5r19.png differ diff --git a/main/_images/sec_catalog_homsap_models_papuansoutofafrica_10j19.png b/main/_images/sec_catalog_homsap_models_papuansoutofafrica_10j19.png index 4575759..62b97ff 100644 Binary files a/main/_images/sec_catalog_homsap_models_papuansoutofafrica_10j19.png and b/main/_images/sec_catalog_homsap_models_papuansoutofafrica_10j19.png differ diff --git a/main/_images/sec_catalog_orysat_models_bottleneckmigration_3c07.png b/main/_images/sec_catalog_orysat_models_bottleneckmigration_3c07.png index d64efc0..16d1616 100644 Binary files a/main/_images/sec_catalog_orysat_models_bottleneckmigration_3c07.png and b/main/_images/sec_catalog_orysat_models_bottleneckmigration_3c07.png differ diff --git a/main/_images/sec_catalog_pantro_models_bonoboghost_4k19.png b/main/_images/sec_catalog_pantro_models_bonoboghost_4k19.png index fb130ab..c7917af 100644 Binary files a/main/_images/sec_catalog_pantro_models_bonoboghost_4k19.png and b/main/_images/sec_catalog_pantro_models_bonoboghost_4k19.png differ diff --git a/main/_images/sec_catalog_ponabe_models_twospecies_2l11.png b/main/_images/sec_catalog_ponabe_models_twospecies_2l11.png index 8a24f56..2fe0fb5 100644 Binary files a/main/_images/sec_catalog_ponabe_models_twospecies_2l11.png and b/main/_images/sec_catalog_ponabe_models_twospecies_2l11.png differ diff --git a/main/_modules/stdpopsim/slim_engine.html b/main/_modules/stdpopsim/slim_engine.html index 48cee44..0bbefa8 100644 --- a/main/_modules/stdpopsim/slim_engine.html +++ b/main/_modules/stdpopsim/slim_engine.html @@ -1005,7 +1005,7 @@
extended_events = copy.deepcopy(extended_events)
# Reassign event times according to integral SLiM ticks.
- # This collapses the time deltas used in HomSap/AmericanAdmixture_4B11,
+ # This collapses the time deltas used in HomSap/AmericanAdmixture_4B18,
# and calculates times for GenerationAfter objects.
def fix_time(event):
for attr in ("time", "start_time", "end_time"):
diff --git a/main/_modules/stdpopsim/species.html b/main/_modules/stdpopsim/species.html
index a63df87..48cdbc4 100644
--- a/main/_modules/stdpopsim/species.html
+++ b/main/_modules/stdpopsim/species.html
@@ -82,6 +82,7 @@ Source code for stdpopsim.species
"""
import logging
+import warnings
import attr
@@ -335,6 +336,17 @@ Source code for stdpopsim.species
right=right,
)
+ def _warn_browning(self, model_id):
+ if model_id == "AmericanAdmixture_4B11":
+ warnings.warn(
+ "In stdpopsim <= 0.2.1, the AmericanAdmixture_4B18 model "
+ "was named AmericanAdmixture_4B11; but since it comes "
+ "from a 2018 paper, this is corrected. The model name "
+ "AmericanAdmixture_4B11 will work for now but is deprecated."
+ )
+ model_id = "AmericanAdmixture_4B18"
+ return model_id
+
[docs] def get_demographic_model(self, id):
"""
Returns a demographic model with the specified ``id``.
@@ -346,6 +358,8 @@ Source code for stdpopsim.species
:rtype: :class:`DemographicModel`
:return: A :class:`DemographicModel` that defines the requested model.
"""
+ # TODO: remove this after a release or two. See #841.
+ id = self._warn_browning(id)
for model in self.demographic_models:
if model.id == id:
return model
diff --git a/main/_sources/tutorial.rst.txt b/main/_sources/tutorial.rst.txt
index 5b05c82..5c21185 100644
--- a/main/_sources/tutorial.rst.txt
+++ b/main/_sources/tutorial.rst.txt
@@ -475,7 +475,7 @@ demographic models are available for humans:
# OutOfAfrica_3G09
# OutOfAfrica_2T12
# Africa_1T12
- # AmericanAdmixture_4B11
+ # AmericanAdmixture_4B18
# OutOfAfricaArchaicAdmixture_5R19
# Zigzag_1S14
# AncientEurasia_9K19
@@ -1557,8 +1557,8 @@ This prints detailed information about all of the available models to
the terminal.
In this tutorial, we will use the model of African-American admixture from
`Browning et al. (2018) `_.
-From the help output (or the :ref:`Catalog `),
-we can see that this model has id ``AmericanAdmixture_4B11``,
+From the help output (or the :ref:`Catalog `),
+we can see that this model has id ``AmericanAdmixture_4B18``,
and allows samples to be drawn from 4 contemporary populations representing African,
European, Asian and African-American groups.
@@ -1577,7 +1577,7 @@ To check that we have set up the simulation correctly, we may first wish to perf
dry run using the ``-D`` option.
This will print information about the simulation to the terminal:
-.. command-output:: stdpopsim HomSap -c chr1 -o afr-america-chr1.trees -s 13 -g HapMapII_GRCh38 -d AmericanAdmixture_4B11 AFR:2 EUR:2 ASIA:2 ADMIX:2 -D
+.. command-output:: stdpopsim HomSap -c chr1 -o afr-america-chr1.trees -s 13 -g HapMapII_GRCh38 -d AmericanAdmixture_4B18 AFR:2 EUR:2 ASIA:2 ADMIX:2 -D
:ellipsis: 18
Once we're sure, we can remove the ``-D`` flag to run the simulation
@@ -1586,7 +1586,7 @@ Once we're sure, we can remove the ``-D`` flag to run the simulation
.. code-block:: console
$ stdpopsim HomSap -c chr1 -o afr-america-chr1.trees -s 13 -g HapMapII_GRCh38 \
- $ -d AmericanAdmixture_4B11 AFR:2 EUR:2 ASIA:2 ADMIX:2
+ $ -d AmericanAdmixture_4B18 AFR:2 EUR:2 ASIA:2 ADMIX:2
2. Calculating divergences
--------------------------
diff --git a/main/catalog.html b/main/catalog.html
index efa9c51..4dd3268 100644
--- a/main/catalog.html
+++ b/main/catalog.html
@@ -214,7 +214,7 @@
Three population out-of-Africa
Two population out-of-Africa
African population
-American admixture
+American admixture
Three population out-of-Africa with archaic admixture
Periodic growth and decline.
Multi-population model of ancient Eurasia
@@ -5776,7 +5776,7 @@ Genome
African population
-
+
American admixture
@@ -6265,8 +6265,8 @@ Genome
-
-American admixture
+
+American admixture
Demographic model for American admixture, taken from Browning et al. 2018.
This model extends the Gravel et al. (2011) model of African/European/Asian
@@ -6281,7 +6281,7 @@
GenomeDetails
- ID:
-AmericanAdmixture_4B11
+AmericanAdmixture_4B18
- Description:
American admixture
@@ -6427,7 +6427,7 @@ Genome
+
Three population out-of-Africa with archaic admixture
diff --git a/main/changelogs.html b/main/changelogs.html
index e70dcb9..888d330 100644
--- a/main/changelogs.html
+++ b/main/changelogs.html
@@ -98,6 +98,9 @@ [0.2.1a] - 2024-07-06
+The 2018 Browning et al HomSap demographic model previously named
+“AmericanAdmixture_4B11” is now named “AmericanAdmixture_4B18”; the old name
+works but throws a deprecation warning. (@petrelharp, #1603)
- The time_units attribute of tree sequence metadata is now set to “generations”
for SLiM output, avoiding the “time units mismatch warning”.
(@nspope, #1567)
diff --git a/main/cli_arguments.html b/main/cli_arguments.html
index a82dd5a..283486d 100644
--- a/main/cli_arguments.html
+++ b/main/cli_arguments.html
@@ -1866,8 +1866,8 @@ Named ArgumentsDefault: False
- -d, --demographic-model
-Possible choices: OutOfAfricaExtendedNeandertalAdmixturePulse_3I21, OutOfAfrica_3G09, OutOfAfrica_2T12, Africa_1T12, AmericanAdmixture_4B11, OutOfAfricaArchaicAdmixture_5R19, Zigzag_1S14, AncientEurasia_9K19, PapuansOutOfAfrica_10J19, AshkSub_7G19, OutOfAfrica_4J17, Africa_1B08, AncientEurope_4A21
-Specify a simulation model. If no model is specified, a single population constant size model is used. Available models: OutOfAfricaExtendedNeandertalAdmixturePulse_3I21, OutOfAfrica_3G09, OutOfAfrica_2T12, Africa_1T12, AmericanAdmixture_4B11, OutOfAfricaArchaicAdmixture_5R19, Zigzag_1S14, AncientEurasia_9K19, PapuansOutOfAfrica_10J19, AshkSub_7G19, OutOfAfrica_4J17, Africa_1B08, AncientEurope_4A21. Please see –help-models for details of these models.
+Possible choices: OutOfAfricaExtendedNeandertalAdmixturePulse_3I21, OutOfAfrica_3G09, OutOfAfrica_2T12, Africa_1T12, AmericanAdmixture_4B18, OutOfAfricaArchaicAdmixture_5R19, Zigzag_1S14, AncientEurasia_9K19, PapuansOutOfAfrica_10J19, AshkSub_7G19, OutOfAfrica_4J17, Africa_1B08, AncientEurope_4A21
+Specify a simulation model. If no model is specified, a single population constant size model is used. Available models: OutOfAfricaExtendedNeandertalAdmixturePulse_3I21, OutOfAfrica_3G09, OutOfAfrica_2T12, Africa_1T12, AmericanAdmixture_4B18, OutOfAfricaArchaicAdmixture_5R19, Zigzag_1S14, AncientEurasia_9K19, PapuansOutOfAfrica_10J19, AshkSub_7G19, OutOfAfrica_4J17, Africa_1B08, AncientEurope_4A21. Please see –help-models for details of these models.
- --dfe
Possible choices: Gamma_K17, Gamma_H17, LogNormal_H17, Mixed_K23
diff --git a/main/objects.inv b/main/objects.inv
index 80fbc88..57d613e 100644
Binary files a/main/objects.inv and b/main/objects.inv differ
diff --git a/main/searchindex.js b/main/searchindex.js
index c0cc89d..c4ff5e9 100644
--- a/main/searchindex.js
+++ b/main/searchindex.js
@@ -1 +1 @@
-Search.setIndex({"docnames": ["api", "catalog", "changelogs", "cli_arguments", "development", "index", "installation", "introduction", "tutorial"], "filenames": ["api.rst", "catalog.rst", "changelogs.rst", "cli_arguments.rst", "development.rst", "index.rst", "installation.rst", "introduction.rst", "tutorial.rst"], "titles": ["API", "Catalog", "Changelogs", "Command-line options", "Development", "Welcome to stdpopsim\u2019s documentation!", "Installation", "Introduction", "Tutorials"], "terms": {"function": [0, 1, 4, 6, 8], "get": [0, 1, 2, 5, 6, 8], "thing": [0, 4, 8], "class": [0, 2], "object": [0, 1, 4, 8], "The": [0, 1, 2, 3, 4, 6, 7], "catalog": [0, 2, 3, 4, 5, 7, 8], "contain": [0, 1, 4, 6, 8], "larg": [0, 4, 8], "number": [0, 1, 3, 4, 7, 8], "which": [0, 1, 2, 3, 6, 8], "ar": [0, 1, 2, 3, 6, 7, 8], "built": [0, 4, 6, 8], "us": [0, 1, 2, 3, 6, 7], "defin": [0, 1, 2, 4, 8], "here": [0, 1, 2, 4, 6, 7, 8], "These": [0, 1, 3, 4, 8], "usual": [0, 4, 6, 8], "intend": 0, "instanti": 0, "directli": [0, 1, 4, 8], "should": [0, 1, 3, 4, 6, 8], "access": [0, 1, 4, 8], "through": [0, 4, 6, 7, 8], "main": [0, 1, 4, 8], "entri": [0, 8], "point": [0, 1, 2, 4], "get_speci": [0, 4, 8], "stdpopsim": [0, 1, 2, 3, 6, 7], "id": [0, 1, 2, 3, 4, 8], "sourc": [0, 1, 4, 7, 8], "return": [0, 4, 8], "specifi": [0, 2, 3, 4], "paramet": [0, 1, 2, 5, 8], "str": [0, 4], "string": [0, 4, 8], "identifi": [0, 1, 4], "request": [0, 2, 4, 7, 8], "e": [0, 1, 2, 3, 4, 7, 8], "g": [0, 1, 2, 3, 4, 7, 8], "homsap": [0, 1, 2, 4, 8], "A": [0, 1, 3, 4, 7], "complet": [0, 4, 6, 8], "list": [0, 1, 2, 3, 4, 7, 8], "can": [0, 1, 2, 3, 4, 6, 7, 8], "found": [0, 1, 4, 8], "an": [0, 2, 3, 4, 7], "type": [0, 1, 2, 4, 8], "repres": [0, 1, 4, 8], "variabl": [0, 3, 6], "uniqu": [0, 4, 8], "thi": [0, 1, 2, 3, 4, 6, 7, 8], "three": [0, 2, 4, 8], "first": [0, 1, 4, 5], "letter": [0, 4], "genu": 0, "name": [0, 1, 2, 5, 8], "follow": [0, 1, 4, 6, 8], "doe": [0, 1, 4, 8], "ani": [0, 1, 2, 3, 4, 8], "space": [0, 3, 4, 8], "punctuat": 0, "scheme": [0, 1, 2, 4], "similar": [0, 2, 4, 8], "approach": 0, "ucsc": [0, 4], "genom": [0, 2, 3, 4, 7], "browser": [0, 4], "homo": [0, 3, 4, 5, 8], "sapien": [0, 3, 4, 5, 8], "full": [0, 3, 4, 6], "binomin": 0, "nomenclatur": 0, "would": [0, 2, 4, 7, 8], "written": [0, 3, 4, 8], "text": [0, 1, 4, 8], "common_nam": [0, 4], "most": [0, 1, 2, 4, 6, 7, 8], "often": [0, 4, 8], "inform": [0, 1, 2, 3, 8], "human": [0, 1, 4, 8], "orang": [0, 1], "utan": [0, 1], "where": [0, 1, 2, 3, 4, 6, 8], "common": [0, 1, 4, 8], "exist": [0, 1, 4, 8], "abbrevi": [0, 4], "coli": [0, 3, 5, 8], "instanc": [0, 1, 3, 4, 8], "describ": [0, 1, 4, 7, 8], "detail": [0, 1, 2, 3, 4, 6, 7, 8], "generation_tim": [0, 2, 4], "float": 0, "current": [0, 1, 4, 7, 8], "best": [0, 1, 4, 7], "estim": [0, 2, 4, 8], "time": [0, 1, 2, 3, 4, 8], "year": [0, 1, 4, 7], "note": [0, 1, 3, 4, 8], "individu": [0, 2, 3, 4, 7, 8], "mai": [0, 3, 4, 6, 7, 8], "each": [0, 1, 2, 3, 4, 8], "wa": [0, 1, 2, 4, 6, 8], "origin": [0, 2, 4, 7, 8], "public": [0, 1, 2, 4, 7], "s": [0, 1, 2, 3, 4, 7, 8], "ploidi": [0, 1, 2, 4, 8], "int": [0, 4, 8], "organ": [0, 1, 7], "population_s": [0, 4, 8], "popul": [0, 2, 3, 4, 7, 8], "size": [0, 2, 3, 4, 8], "citat": [0, 1, 2, 3, 4, 5, 8], "provid": [0, 1, 2, 3, 4, 7, 8], "demographic_model": [0, 4, 8], "demographicmodel": [0, 1, 4], "ensembl_id": [0, 4], "ensembl": [0, 1, 2, 4, 8], "mainten": [0, 1, 2, 4], "script": [0, 1, 3, 4], "queri": 0, "databas": [0, 1], "get_annot": [0, 8], "set": [0, 1, 2, 3, 6], "annot": [0, 2, 3, 5, 8], "subsect": 0, "hold": 0, "from": [0, 1, 2, 3, 4, 7], "get_contig": [0, 8], "chromosom": [0, 1, 2, 3, 4, 8], "none": [0, 1, 3, 4], "genetic_map": [0, 3, 4, 8], "length_multipli": [0, 3, 8], "1": [0, 1, 3, 4, 5], "length": [0, 1, 2, 3, 4, 8], "mutation_r": [0, 4, 8], "recombination_r": [0, 4], "use_species_gene_convers": 0, "fals": [0, 2, 3, 8], "inclusion_mask": [0, 3, 8], "exclusion_mask": [0, 3, 8], "left": [0, 2, 3, 8], "right": [0, 2, 3, 4, 6, 8], "contig": [0, 2, 3, 4], "section": [0, 4, 8], "base": [0, 1, 4, 8], "empir": [0, 8], "given": [0, 1, 3, 4, 8], "coordin": [0, 2, 3], "If": [0, 3, 4, 7, 8], "particular": [0, 3, 6, 7, 8], "chunk": [0, 8], "obtain": [0, 1, 4, 6, 8], "result": [0, 2, 4, 8], "have": [0, 1, 2, 3, 8], "match": [0, 2, 4, 8], "portion": [0, 8], "outsid": [0, 2, 3, 8], "mask": [0, 2, 3], "so": [0, 1, 2, 3, 4, 7, 8], "miss": [0, 2, 4], "data": [0, 1, 2, 4], "shift": [0, 2], "rel": [0, 2, 8], "desir": [0, 8], "output": [0, 1, 2, 3, 4], "tskit": [0, 3, 4, 8], "treesequ": [0, 2, 8], "trim": [0, 2], "method": [0, 1, 2, 4, 6, 8], "ts_shift": 0, "ts": [0, 2, 8], "we": [0, 1, 2, 3, 4, 6, 7, 8], "rate": [0, 1, 2, 3, 4, 8], "genet": [0, 2, 5, 7], "map": [0, 2, 5], "default": [0, 2, 3, 4, 6, 8], "uniform": [0, 2, 3, 4, 8], "region": [0, 1, 2, 4, 8], "specif": [0, 1, 2, 4, 5, 6, 8], "same": [0, 1, 3, 4, 6, 8], "mutat": [0, 1, 2, 3, 4, 8], "option": [0, 1, 2, 4, 5, 6], "cannot": [0, 4, 8], "conjunct": 0, "argument": [0, 2, 4, 5, 8], "per": [0, 1, 2, 4, 7, 8], "ignor": [0, 4], "when": [0, 1, 6, 8], "bool": 0, "true": [0, 2, 8], "avail": [0, 1, 3, 4, 6, 7, 8], "For": [0, 1, 3, 4, 7, 8], "fraction": [0, 1, 8], "mean": [0, 1, 2, 4, 6, 8], "valu": [0, 1, 2, 3, 4, 8], "across": [0, 1, 3, 4, 8], "all": [0, 1, 2, 3, 4, 7, 8], "subset": [0, 1, 8], "onli": [0, 1, 4, 8], "inlud": 0, "path": [0, 3, 6, 8], "file": [0, 1, 2, 3, 4, 8], "bed": [0, 2, 3, 8], "arrai": [0, 1, 8], "interv": [0, 1, 2, 3, 8], "end": [0, 1, 3, 4, 8], "exclud": 0, "sequenc": [0, 1, 2, 3, 4, 7], "equal": [0, 1, 4], "wide": [0, 1, 4], "averag": [0, 1, 4, 8], "autosom": [0, 1, 2, 8], "inclus": [0, 2, 3, 4, 7], "keep": [0, 2, 3, 8], "0": [0, 1, 3, 4, 5, 8], "remain": [0, 4], "exclus": [0, 2, 3], "get_demographic_model": [0, 4, 8], "get_df": [0, 8], "todo": 0, "add": [0, 2, 6, 8], "assembly_nam": 0, "assembl": [0, 1, 2, 4], "assembly_access": 0, "bacterial_recombin": 0, "whether": [0, 3, 4, 8], "via": [0, 1, 2, 4, 8], "horizont": 0, "transfer": 0, "cross": [0, 1, 4, 8], "over": [0, 1, 2, 3, 5, 8], "possibl": [0, 1, 2, 3, 4, 6, 7, 8], "total": [0, 1, 4, 8], "static": 0, "from_data": [0, 4], "genome_data": [0, 4], "gene_conversion_fract": 0, "gene_conversion_length": 0, "construct": [0, 1], "dictionari": [0, 4], "intern": [0, 1, 4, 8], "get_chromosom": [0, 4], "properti": [0, 4], "mean_gene_conversion_fract": 0, "weight": [0, 4], "mean_mutation_r": 0, "mean_recombination_r": 0, "doubl": [0, 1, 4], "strand": 0, "break": [0, 2, 8], "range_gene_conversion_length": 0, "rang": [0, 1, 4, 8], "tract": [0, 1, 3], "singl": [0, 1, 2, 3, 4], "although": [0, 6, 8], "give": [0, 1, 4, 8], "both": [0, 1, 3, 4, 8], "differ": [0, 1, 2, 4, 6, 8], "nonzero": 0, "event": [0, 1, 2, 4, 8], "synonym": [0, 1, 4, 8], "command": [0, 1, 2, 4, 5, 6], "line": [0, 1, 2, 4, 5, 6], "interfac": [0, 1, 3, 4, 5, 6], "contigu": 0, "about": [0, 1, 4, 8], "distribut": [0, 2, 3, 4, 8], "fit": [0, 2, 3, 4, 8], "effect": [0, 2, 3, 4, 8], "need": [0, 1, 3, 6, 8], "target": 0, "dfe_list": 0, "interval_list": 0, "must": [0, 1, 3, 4, 8], "k": [0, 7, 8], "th": 0, "appli": [0, 4, 8], "see": [0, 1, 2, 3, 4, 6, 7, 8], "add_df": [0, 4, 8], "more": [0, 1, 2, 4, 6, 8], "2": [0, 1, 3, 4, 5], "diploid": [0, 1, 3, 8], "geneticmap": [0, 1, 2, 4], "recombination_map": [0, 8], "msprime": [0, 2, 4, 5, 6, 7, 8], "ratemap": 0, "larger": [0, 8], "than": [0, 1, 2, 3, 4, 6, 8], "correspond": [0, 1, 4, 8], "sinc": [0, 1, 4, 8], "i": [0, 1, 3, 8], "resolv": [0, 2, 4], "between": [0, 1, 2, 4, 8], "tranfer": 0, "segment": [0, 2, 8], "present": [0, 1, 4, 8], "abov": [0, 1, 4, 6, 8], "either": [0, 3, 4, 6, 8], "mask_interv": 0, "like": [0, 1, 4, 6, 7, 8], "tree": [0, 1, 2, 3, 7], "left_posit": 0, "right_posit": 0, "non": [0, 1, 2, 3, 4, 8], "overlap": [0, 1, 3], "ascend": 0, "order": [0, 4, 8], "shape": [0, 1, 4], "nx2": 0, "n": [0, 3, 7, 8], "By": [0, 3, 8], "neutral": [0, 1, 3, 4, 8], "np": [0, 8], "integ": [0, 2, 8], "init": 0, "span": [0, 8], "whole": [0, 1, 8], "tupl": [0, 8], "locat": [0, 1, 8], "form": [0, 1, 2, 4], "assum": [0, 1, 4, 8], "inherit": [0, 1], "system": [0, 4, 6, 8], "To": [0, 1, 2, 4, 8], "run": [0, 1, 2, 3, 4, 5, 7], "altern": [0, 4], "user": [0, 2, 4, 6, 8], "new": [0, 1, 2, 5, 8], "creat": [0, 4, 7, 8], "one": [0, 1, 2, 3, 4, 6], "new_contig": 0, "old_contig": 0, "also": [0, 1, 2, 3, 4, 6, 8], "remov": [0, 1, 2, 4, 8], "previous": [0, 1, 2], "other": [0, 1, 2, 4, 7], "word": [0, 8], "recent": [0, 1, 4, 6], "ad": [0, 1, 2, 5, 8], "take": [0, 2, 3, 4, 8], "preced": [0, 3, 8], "wai": [0, 4, 6, 8], "carri": [0, 8], "its": [0, 4, 6], "own": [0, 4], "mutationtyp": [0, 2, 4, 8], "share": [0, 4, 8], "call": [0, 1, 2, 4, 8], "even": [0, 4, 8], "onc": [0, 4, 6, 8], "do": [0, 1, 3, 6, 8], "a1": [0, 4], "100": [0, 1, 4, 8], "a2": [0, 4], "50": [0, 1, 8], "120": [0, 1], "dfe1": 0, "dfe2": 0, "fall": [0, 8], "clip": [0, 8], "boundari": [0, 8], "empti": [0, 4], "warn": [0, 2], "valid": [0, 1, 4], "add_single_sit": [0, 8], "descript": [0, 1, 3, 4, 8], "long_descript": [0, 4, 8], "site": [0, 1, 8], "label": [0, 1, 4, 8], "referenc": 0, "extend": [0, 2, 8], "pass": [0, 2, 4, 8], "pop_0": [0, 8], "start": [0, 1, 3, 4, 8], "1000": [0, 1, 3, 4, 8], "past": [0, 1, 4], "hard_sweep": 0, "mutation_coordin": 0, "extended_ev": [0, 8], "ext": [0, 2], "selective_sweep": [0, 8], "mutation_generation_ago": [0, 8], "selection_coeff": [0, 8], "get_engin": [0, 8], "slim": [0, 1, 2, 4, 5, 7], "ts_sweep": [0, 8], "short": [0, 4], "strong": 0, "necessari": [0, 2, 4, 6, 8], "summari": [0, 1, 8], "clear_df": 0, "well": [0, 1, 2, 4, 7, 8], "dfe_breakpoint": [0, 2, 8], "relative_coordin": [0, 2], "two": [0, 2, 3, 4, 6, 8], "sort": 0, "vector": 0, "endpoint": [0, 8], "sai": [0, 3, 4, 8], "goe": 0, "complementari": 0, "tell": [0, 8], "bit": [0, 4, 8], "ha": [0, 1, 2, 3, 4, 6, 8], "attach": [0, 8], "conveni": [0, 6], "column": [0, 4], "suppos": [0, 1, 4, 8], "cover": [0, 4, 8], "dfe_label": 0, "those": [0, 1, 2, 3, 4, 6, 8], "increas": [0, 1, 3, 8], "index": [0, 1, 2, 4, 5, 8], "alwai": 0, "j": [0, 1, 4, 7, 8], "some": [0, 1, 2, 4, 6, 7, 8], "case": [0, 2, 4, 6, 8], "thei": [0, 1, 2, 3, 4, 8], "bewar": [0, 4], "python": [0, 1, 4, 5, 6], "is_neutr": 0, "mutation_typ": [0, 4], "assign": [0, 4], "along": [0, 4, 8], "becaus": [0, 1, 4, 8], "numer": [0, 2, 3], "encount": [0, 4, 6], "iter": 0, "easi": [0, 1, 4, 8], "back": [0, 4, 8], "dfe_id": 0, "come": [0, 1, 8], "mut": [0, 8], "code": [0, 1, 2, 3, 5, 7, 8], "print": [0, 3, 4, 8], "mut_typ": 0, "m": [0, 4, 6, 7], "md": 0, "metadata": [0, 2, 8], "muation_list": 0, "f": [0, 4, 7, 8], "join": [0, 4, 7], "format": [0, 1, 3, 4, 7, 8], "species_contig": 0, "build": [0, 4, 7, 8], "literatur": [0, 3, 4, 8], "acknowledg": 0, "doi": [0, 1, 4, 7, 8], "author": [0, 1, 4, 7], "et": [0, 4, 8], "al": [0, 4, 8], "4": [0, 2, 3, 4, 7], "digit": [0, 4, 8], "2008": [0, 1, 8], "assert_valid": 0, "check": [0, 1], "reason": [0, 4, 8], "fetch_bibtex": 0, "retriev": [0, 1], "bibtex": [0, 3, 7], "crossref": 0, "merg": [0, 4], "dedupl": 0, "track": [0, 1, 2, 3, 4, 8], "url": [0, 4, 7], "pack": 0, "compress": [0, 4], "gff3": 0, "intervals_url": 0, "cach": [0, 3, 4], "intervals_sha256": 0, "sha256": [0, 4], "checksum": [0, 4], "One": [0, 4, 8], "file_pattern": [0, 4], "pattern": [0, 4], "download": [0, 1, 4, 8], "store": [0, 2, 3, 4, 8], "directori": [0, 3, 4, 6], "get_chromosome_annot": [0, 8], "numpi": [0, 8], "is_cach": 0, "local": [0, 4, 6], "implementor": 0, "develop": [0, 1, 5, 7], "document": [0, 2, 3, 6, 7, 8], "instead": [0, 2, 4, 8], "pre": [0, 6], "memor": 0, "conform": [0, 4], "convent": [0, 5], "out": [0, 2, 4, 6, 7, 8], "africa": [0, 2, 4, 8], "itself": [0, 8], "concis": [0, 8], "inter": 0, "primari": [0, 4, 7], "associ": [0, 2, 4, 8], "get_sample_set": 0, "individuals_per_popul": 0, "sampleset": 0, "sampl": [0, 2, 3, 4, 7], "5": [0, 1, 2, 3, 4, 6], "pop_1": 0, "encompass": 0, "10": [0, 1, 2, 3, 4, 7, 8], "split": [0, 4, 8], "omit": [0, 3, 8], "zero": [0, 3, 8], "dict": 0, "population_nam": [0, 8], "number_of_sampl": [0, 8], "count": [0, 4, 8], "get_sampl": 0, "arg": 0, "haploid": [0, 2, 8], "determin": [0, 4, 8], "posit": [0, 2, 4, 5, 8], "7": [0, 1, 3, 4, 8], "14": [0, 1, 3, 8], "five": [0, 4, 8], "second": [0, 1, 4, 8], "seven": [0, 4], "third": [0, 1, 8], "less": [0, 1, 4, 8], "num_sampling_popul": [0, 8], "treat": [0, 1], "register_qc": [0, 4], "qc_model": 0, "regist": [0, 4], "qc": [0, 2, 4], "implement": [0, 1, 8], "record": [0, 2, 4, 7, 8], "sampling_tim": 0, "indic": [0, 4, 8], "how": [0, 1, 4, 6, 7, 8], "mani": [0, 2, 4, 8], "prior": 0, "drawn": [0, 4, 8], "allow": [0, 2, 4, 8], "asdict": 0, "process": [0, 1, 8], "howev": [0, 4, 6, 8], "happen": [0, 4, 8], "unfortun": 0, "make": [0, 1, 5, 6, 7, 8], "much": [0, 4, 8], "longer": [0, 2, 4, 8], "bigger": 0, "higher": [0, 8], "enabl": [0, 4], "runtim": 0, "attribut": [0, 2, 4], "visibl": 0, "r": [0, 1, 4, 7, 8], "consequ": [0, 8], "initi": [0, 1, 2, 4, 8], "terminolog": 0, "conflict": [0, 4], "somewhat": [0, 8], "otherwis": [0, 3, 4, 8], "includ": [0, 1, 4, 8], "dromel": [0, 1, 2, 4, 8], "2l": [0, 1, 3, 4, 8], "mean_rat": [0, 8], "40462600791e": 0, "08": [0, 1, 3, 8], "414485887005882e": 0, "07": [0, 1, 3, 5, 8], "write": [0, 2, 3, 4], "constant": [0, 3, 8], "while": [0, 1, 4, 8], "fix": [0, 1, 2, 4, 8], "In": [0, 1, 4, 6, 8], "principl": [0, 8], "issu": [0, 1, 2, 4, 7], "mechan": 0, "flag": [0, 2, 8], "It": [0, 1, 4, 6, 8], "could": [0, 4, 8], "homolog": 0, "anoth": [0, 4], "kind": 0, "collect": [0, 4], "overal": 0, "proport": [0, 1, 4, 8], "entir": [0, 3, 4, 8], "occur": [0, 1, 4, 8], "nonneg": 0, "sum": [0, 4, 8], "lognorm": [0, 1, 4], "qc_dfe": 0, "design": [0, 4, 7, 8], "close": [0, 4, 8], "mirror": 0, "draw": [0, 3, 8], "coeffici": [0, 2, 4, 8], "distribution_typ": [0, 4], "manual": [0, 1, 3, 4, 8], "exponenti": [0, 1, 2], "gamma": [0, 1, 4, 8], "normal": [0, 1], "sd": 0, "w": [0, 7, 8], "weibul": 0, "scale": [0, 3, 4], "u": 0, "min": 0, "max": [0, 4, 8], "lp": 0, "log": [0, 1, 3, 4], "rlnorm": 0, "ln": 0, "neg": [0, 1, 4, 8], "multipli": [0, 3], "domin": [0, 1, 2, 4], "dominance_coeff": [0, 4], "discret": [0, 2], "relationship": [0, 2, 8], "dominance_coeff_list": [0, 2], "dominance_coeff_break": 0, "below": [0, 4, 8], "forth": [0, 4, 8], "therefor": [0, 8], "distribution_arg": [0, 4], "underdomin": 0, "recess": 0, "addit": [0, 1, 2, 4, 7, 8], "overdomin": 0, "convert_to_substitut": 0, "retain": [0, 2, 8], "ask": [0, 4, 8], "frequenc": [0, 1, 2], "shorter": [0, 4, 8], "test": [0, 1, 5, 7, 8], "strictli": 0, "situat": [0, 8], "produc": [0, 1, 2, 4, 8], "extendedev": 0, "subclass": 0, "condit": [0, 2, 8], "loci": 0, "chang": [0, 1, 2, 3, 4, 8], "futur": [0, 4], "stabl": [0, 3, 4], "single_site_id": [0, 8], "start_generation_ago": 0, "end_generation_ago": 0, "min_freq_at_start": 0, "min_freq_at_end": [0, 8], "globally_adapt": 0, "subsequ": [0, 1], "introduc": [0, 8], "becom": [0, 4], "benefici": [0, 1, 4, 8], "global": [0, 7], "control": [0, 2], "restart": 0, "after": [0, 1, 4, 6, 8], "revert": 0, "dure": [0, 1, 4, 6, 8], "homozyg": [0, 1], "heterozyg": 0, "respect": [0, 1, 4, 8], "impact": [0, 8], "regardless": [0, 3, 4, 7, 8], "belong": [0, 3], "influenc": [0, 8], "within": [0, 1, 4, 8], "lost": [0, 4], "aka": 0, "reject": [0, 4], "being": [0, 4, 8], "extant": 0, "until": [0, 4, 8], "allel": [0, 1, 2, 3], "satisfi": [0, 4], "care": [0, 4, 8], "taken": [0, 1, 4, 8], "ensur": [0, 4], "exampl": [0, 4, 5, 7], "veri": [0, 4, 8], "substanti": [0, 1, 8], "greater": [0, 8], "vast": 0, "major": [0, 2, 7], "propos": [0, 8], "trajectori": 0, "infeas": 0, "long": [0, 1, 2, 4, 8], "switch": [0, 2, 8], "hard": [0, 4, 8], "minimum": [0, 4], "abl": [0, 4, 8], "pleas": [0, 1, 3, 4, 6, 7], "piecewiseconstants": [0, 1, 8], "n0": 0, "piecewis": [0, 8], "instantan": [0, 1, 8], "multipl": [0, 1, 3, 4], "epoch": [0, 8], "t": [0, 3, 4, 8], "place": [0, 4], "usag": [0, 3, 5, 8], "illustr": [0, 8], "model1": 0, "t1": 0, "n1": [0, 1, 8], "model2": 0, "t2": 0, "n2": [0, 8], "isolationwithmigr": [0, 1, 8], "na": [0, 8], "m12": [0, 8], "m21": [0, 8], "isol": [0, 1, 8], "migrat": [0, 2, 4, 8], "ancestr": [0, 1, 2, 4, 8], "ago": [0, 1, 8], "disallow": 0, "support": [0, 2, 4, 7, 8], "abstract": 0, "register_engin": 0, "get_default_engin": 0, "At": [0, 3, 4, 8], "get_vers": 0, "py": [0, 1, 4], "version": [0, 1, 3, 4, 6], "seed": [0, 3, 8], "dry_run": 0, "random": [0, 3, 8], "without": [0, 1, 3, 4, 6, 8], "succinct": 0, "_msprimeengin": 0, "coalesc": [0, 1, 8], "msprime_model": 0, "msprime_change_model": 0, "kwarg": 0, "hudson": [0, 3, 8], "dtwf": [0, 2, 3, 8], "smc": [0, 2, 3, 8], "smc_prime": [0, 3, 8], "end_tim": 0, "initialis": 0, "immedi": 0, "further": [0, 1, 4, 7, 8], "sim_ancestri": 0, "slim_engin": 0, "_slimengin": 0, "forward": [0, 4, 8], "wright": 0, "fisher": 0, "recap_and_rescal": [0, 8], "slim_scaling_factor": [0, 8], "keep_mutation_ids_as_allel": 0, "post": [0, 1], "transform": 0, "rescal": [0, 3, 8], "node": [0, 8], "recapit": [0, 8], "simplif": [0, 1, 8], "procedur": [0, 4, 8], "been": [0, 1, 2, 4, 7, 8], "had": [0, 1, 8], "were": [0, 1, 2, 4, 8], "hope": 0, "But": [0, 8], "anticip": 0, "what": [0, 2, 6, 7, 8], "you": [0, 1, 3, 4, 6, 7, 8], "ll": [0, 1, 4, 8], "befor": [0, 1, 4, 8], "consult": 0, "behaviour": [0, 8], "appropri": 0, "your": [0, 1, 6, 7, 8], "slim_path": [0, 8], "slim_script": [0, 8], "slim_burn_in": [0, 8], "verbos": [0, 2, 3, 8], "logfil": 0, "logfile_interv": 0, "_recap_and_rescal": 0, "execut": [0, 3, 4, 6], "stdout": [0, 3, 8], "speed": [0, 3, 8], "up": [0, 3, 6], "divid": [0, 8], "factor": [0, 2, 3], "wherea": [0, 2], "growth": [0, 2, 8], "improv": [0, 2, 3, 4, 6, 7], "perform": [0, 1, 2, 3, 4, 8], "burn": [0, 3], "phase": [0, 1, 3, 4, 8], "unit": [0, 1, 2, 3, 5, 8], "setup": [0, 4], "statist": [0, 1, 2, 4, 8], "rather": [0, 3, 4, 6, 8], "randomli": [0, 1, 8], "nucleotid": [0, 2, 3, 8], "With": 1, "simul": [1, 2, 3, 4, 5, 6, 7], "publish": [1, 4, 7], "histori": [1, 4, 7, 8], "rigor": 1, "peopl": 1, "rest": [1, 4, 8], "know": [1, 4, 8], "reproduc": [1, 6, 7, 8], "bug": [1, 2, 7], "free": [1, 4, 7], "show": [1, 3, 4, 8], "configur": [1, 4], "organis": 1, "around": [1, 4, 8], "choic": [1, 3, 8], "speci": [1, 2, 3, 5, 7], "wish": [1, 4, 8], "recombin": [1, 2, 3, 5, 8], "interest": [1, 4, 7, 8], "modern": [1, 8], "22": [1, 3, 4, 8], "hapmapii": 1, "under": [1, 2, 4, 7, 8], "3": [1, 2, 3, 4, 6], "background": [1, 2, 7], "select": [1, 2, 3, 4, 5], "act": [1, 3], "exon": [1, 2], "havana": [1, 8], "104": 1, "yri": [1, 2, 4, 8], "ceu": [1, 2, 8], "chb": [1, 2, 8], "save": [1, 4, 8], "c": [1, 3, 4, 6, 7, 8], "chr22": [1, 3, 8], "o": [1, 3, 4, 8], "d": [1, 2, 3, 4, 7, 8], "outofafrica_3g09": [1, 2, 3, 4, 8], "learn": [1, 4, 7], "read": [1, 4, 7, 8], "our": [1, 4, 7, 8], "tutori": [1, 4, 5, 6, 7], "known": [1, 3, 4], "head": [1, 4, 7], "page": [1, 4, 5, 7], "item": [1, 4], "Then": [1, 4], "feel": [1, 4], "readi": [1, 4, 8], "github": [1, 2, 3, 5, 7], "aedaeg": [1, 8], "yellow": [1, 4], "fever": 1, "mosquito": 1, "06666666666666667": [1, 3], "crawford": 1, "2017": [1, 4, 8], "1000000": [1, 3, 4, 8], "310827022": 1, "06e": 1, "09": [1, 3], "5e": [1, 3], "474425716": 1, "49e": [1, 3], "409777670": 1, "91e": 1, "mt": [1, 3, 4], "16790": 1, "bp": [1, 4], "anapla": [1, 2, 8], "lavretski": 1, "2020": [1, 5, 7], "156000": [1, 3], "guo": 1, "2021": 1, "208326429": 1, "52e": 1, "83e": [1, 3], "162939446": 1, "39e": 1, "119723720": 1, "9": [1, 3, 4, 7, 8], "38e": 1, "77626585": 1, "2e": [1, 3], "64988622": 1, "21e": 1, "6": [1, 2, 3, 4, 8], "39543408": 1, "04e": 1, "37812880": 1, "59e": 1, "8": [1, 3, 4, 8], "33348632": 1, "28e": 1, "26742597": 1, "34e": 1, "22933227": 1, "11": [1, 3, 5, 8], "22193879": 1, "12": [1, 3, 5, 7, 8], "22338721": 1, "15e": 1, "13": [1, 3, 8], "21714986": 1, "41e": 1, "20320564": 1, "61e": 1, "15": [1, 3, 8], "18227546": 1, "79e": 1, "16": [1, 3, 8], "16053328": 1, "86e": 1, "17": [1, 3, 4, 8], "15319648": 1, "13e": 1, "18": [1, 3, 5, 8], "13333155": 1, "58e": 1, "19": [1, 2, 3, 8], "12198306": 1, "43e": 1, "20": [1, 3, 4, 8], "12091001": 1, "21": [1, 3], "8553409": 1, "16160689": 1, "23": [1, 3, 7], "7977799": 1, "24": [1, 3], "7737077": 1, "25": [1, 3], "7574731": 1, "26": [1, 3], "6918023": 1, "27": [1, 3, 4], "6270716": 1, "28": [1, 3], "5960150": 1, "29": [1, 3, 5], "1456683": 1, "30": [1, 3, 8], "1872559": 1, "z": [1, 3], "81233375": 1, "31": [1, 3, 8], "2637124": 1, "3473573": 1, "33": [1, 3, 4, 8], "2151773": 1, "34": [1, 3], "7214884": 1, "35": [1, 3], "5548691": 1, "36": [1, 3, 8], "3997205": 1, "37": [1, 3, 8], "3148754": 1, "38": [1, 3], "2836164": 1, "39": [1, 3, 4], "2018729": 1, "40": [1, 3], "1354177": 1, "mallardblackduck_2l19": [1, 2, 3], "contemporari": [1, 8], "wild": 1, "dadi": 1, "figur": [1, 4, 8], "2019": [1, 4, 5], "num": 1, "black_duck": 1, "158076": 1, "http": [1, 3, 4, 7, 8], "org": [1, 4, 7, 8], "1111": 1, "mec": 1, "15343": 1, "819": 1, "535": 1, "pop": [1, 8], "570": 1, "000": [1, 8], "370": 1, "x10": 1, "gen": 1, "72": 1, "yr": 1, "subst": 1, "anocar": [1, 8], "anol": 1, "lizard": 1, "lovern": 1, "2004": [1, 4], "3050000": [1, 3], "pombi": 1, "263920458": 1, "1e": [1, 3], "199619895": 1, "204416410": 1, "156502444": 1, "150641573": 1, "80741955": 1, "lga": [1, 3], "7025928": 1, "lgb": [1, 3], "3271537": 1, "lgc": [1, 3], "9478905": 1, "lgd": [1, 3], "1094478": 1, "lgf": [1, 3], "4257874": 1, "lgg": [1, 3], "424765": 1, "lgh": [1, 3], "248369": 1, "17223": 1, "anogam": [1, 2, 8], "09090909090909091": [1, 3], "ag1000g": 1, "consortium": [1, 3, 4, 7], "49364325": 1, "3e": [1, 8], "2r": [1, 3], "61545105": 1, "3l": [1, 3], "41963435": 1, "3r": [1, 3], "53200684": 1, "6e": [1, 3], "x": [1, 3, 4, 8], "24393108": 1, "15363": 1, "gabonag1000g_1a17": [1, 2, 3], "done": [1, 4, 6, 8], "part": [1, 4, 8], "paper": [1, 4, 7, 8], "misorient": 1, "sf": [1, 8], "110": [1, 8], "distinct": [1, 4, 8], "report": [1, 4, 8], "tabl": 1, "ga": 1, "1038": 1, "nature24995": 1, "069": 1, "863": [1, 2], "205": [1, 8], "766": 1, "apimel": [1, 8], "dh4": 1, "nelson": 1, "200000": [1, 3], "wallberg": 1, "2014": [1, 2, 4, 8], "cm009931": [1, 3], "27754200": 1, "4e": [1, 3, 8], "cm009932": [1, 3], "16089512": 1, "46e": 1, "cm009933": [1, 3], "13619445": 1, "cm009934": [1, 3], "13404451": 1, "76e": 1, "cm009935": [1, 3], "13896941": 1, "14e": 1, "cm009936": [1, 3], "17789102": 1, "12e": 1, "cm009937": [1, 3], "14198698": 1, "cm009938": [1, 3], "12717210": 1, "09e": 1, "cm009939": [1, 3], "12354651": 1, "cm009940": [1, 3], "12360052": 1, "48e": 1, "cm009941": [1, 3], "16352600": 1, "03e": 1, "cm009942": [1, 3], "11514234": 1, "cm009943": [1, 3], "11279722": 1, "cm009944": [1, 3], "10670842": 1, "cm009945": [1, 3], "9534514": 1, "cm009946": [1, 3], "7238532": 1, "cm009947": [1, 3], "16343": 1, "aratha": [1, 2, 4, 8], "donohu": [1, 4], "2002": [1, 4], "10000": [1, 3, 8], "1001genomesconsortium": [1, 4], "30427671": 1, "06452e": 1, "7e": [1, 3, 4], "19698289": 1, "23459830": 1, "18585056": 1, "26975502": 1, "366924": 1, "pt": [1, 3, 4], "154478": 1, "2012": [1, 8], "crossov": 1, "studi": [1, 4, 8], "7000": 1, "plant": 1, "f2": 1, "deriv": [1, 4, 8], "salom\u00e9": 1, "haldan": 1, "distanc": 1, "convert": [1, 2, 4], "cm": [1, 4], "mb": [1, 4, 8], "loess": 1, "tair7": [1, 4], "lift": [1, 5, 8], "tair10": [1, 4], "hdy": 1, "2011": [1, 8], "95": 1, "southmiddleatlas_1d17": [1, 3], "african2epoch_1h18": [1, 3], "african3epoch_1h18": [1, 3], "msmc": 1, "khe32": 1, "ifr4": 1, "mountain": 1, "morocco": 1, "accur": [1, 4], "8th": 1, "last": [1, 4, 8], "30th": 1, "southmiddleatla": 1, "durvasula": [1, 7], "1073": 1, "pna": 1, "1616736114": 1, "73": 1, "989": 1, "121": 1, "796": 1, "1st": [1, 4], "165": 1, "210": 1, "2nd": [1, 4], "198": 1, "019": 1, "3rd": 1, "217": 1, "752": 1, "4th": 1, "228": 1, "222": 1, "5th": 1, "238": 1, "593": 1, "6th": 1, "246": 1, "984": 1, "7th": 1, "241": 1, "400": 1, "331": 1, "9th": 1, "181": 1, "571": 1, "10th": 1, "143456": 1, "11th": 1, "111": 1, "644": [1, 2], "12th": 1, "91": 1, "813": 1, "13th": 1, "83": 1, "829": 1, "14th": 1, "932": 1, "15th": 1, "87": 1, "661": 1, "16th": 1, "96": 1, "283": 1, "17th": 1, "745": 1, "18th": 1, "132": [1, 2], "19th": 1, "78": 1, "908": 1, "20th": 1, "537": [1, 2], "686": 1, "begin": [1, 3, 8], "119": 1, "341": 1, "954": 1, "517": 1, "610": 1, "693": 1, "151": 1, "590": 1, "173": 1, "502": 1, "139": 1, "426": 1, "879": 1, "362": 1, "541": 1, "307": 1, "540": 1, "260": 1, "520": [1, 2], "220": 1, "324": 1, "185": 1, "960": [1, 2], "156": 1, "584": 1, "131": 1, "471": [1, 2], "001": 1, "648": 1, "75": [1, 3], "958": 1, "62": 1, "544": [1, 8], "51": [1, 2], "077": 1, "spectrum": 1, "snp": [1, 8], "williamson": [1, 8], "2005": [1, 8], "methodolog": 1, "supplementari": 1, "huber": [1, 4], "2018": [1, 8], "n_a": 1, "n_0": 1, "t_1": 1, "s41467": 1, "018": 1, "05281": 1, "746": 1, "148": 1, "218": 1, "568": 1, "344": 1, "n_2": 1, "n_3": 1, "t_2": 1, "t_3": 1, "161": 1, "744": 1, "076": 1, "203": 1, "420": 1, "534": 1, "araport11": 1, "cheng": 1, "dx": 1, "tpj": 1, "13415": 1, "deleteri": [1, 4, 8], "270": 1, "h": [1, 2, 3, 8], "500": 1, "bostau": [1, 2, 8], "62000": [1, 3], "158534110": 1, "26e": [1, 3], "136231102": 1, "121005158": 1, "120000601": 1, "120089316": 1, "117806340": 1, "110682743": 1, "113319770": 1, "105454467": 1, "103308737": 1, "106982474": 1, "87216183": 1, "83472345": 1, "82403003": 1, "85007780": 1, "81013979": 1, "73167244": 1, "65820629": 1, "63449741": 1, "71974595": 1, "69862954": 1, "60773035": 1, "52498615": 1, "62317253": 1, "42350435": 1, "51992305": 1, "45612108": 1, "45940150": 1, "51098607": 1, "139009144": 1, "16338": 1, "holsteinfriesian_1m13": [1, 2, 3], "holsteinfriesian_1b16": [1, 3], "fleckvieh_1b16": [1, 3], "jersey_1b16": [1, 3], "angus_1b16": [1, 3], "homozygos": 1, "observ": [1, 4, 8], "assumpt": [1, 4], "2213": 1, "94e": 1, "2221": 1, "2215": 1, "4a": 1, "s1": 1, "bull": 1, "walkwai": 1, "chief": 1, "mark": [1, 4], "hi": 1, "father": 1, "influentiu": 1, "sire": 1, "breed": 1, "larkin": 1, "www": [1, 8], "cgi": 1, "1114546109": 1, "holstein_friesian": 1, "1093": [1, 4], "molbev": [1, 4], "mst125": 1, "350": 1, "250": [1, 8], "90": 1, "154": 1, "354": 1, "754": 1, "654": 1, "454": 1, "0e": 1, "approxim": [1, 4], "bayesian": [1, 4], "comput": [1, 4, 7, 8], "linkag": [1, 8], "disequlibrium": 1, "minor": 1, "66e": 1, "exact": 1, "lead": [1, 8], "person": [1, 4], "commun": [1, 4, 7], "129": 1, "chose": 1, "52": 1, "australia": 1, "homogen": 1, "sub": [1, 4, 5], "kept": 1, "least": [1, 3, 4, 8], "inbr": 1, "unrel": 1, "1371": 1, "journal": [1, 7], "pgen": 1, "1005877": 1, "652": [1, 8], "65": 1, "485": 1, "86": 1, "206": 1, "79": 1, "079": 1, "71": 1, "209": 1, "841": 1, "63": 1, "092": 1, "882": 1, "726": [1, 2], "512": 1, "155": 1, "783": 1, "159": [1, 8], "602": 1, "367": 1, "892": 1, "815": 1, "320": 1, "793": 1, "999": 1, "043": 1, "53": 1, "045": 1, "881": 1, "638": 1, "817": 1, "821": 1, "629": 1, "287": 1, "455": [1, 8], "923": 1, "47": 1, "89e": 1, "43": 1, "70": 1, "789": 1, "85": 1, "607": 1, "82": 1, "448": 1, "844": 1, "920": [1, 8], "61": 1, "479": 1, "54": 1, "358": 1, "547": [1, 2], "963": 1, "176": 1, "604": 1, "546": 1, "414": 1, "689": 1, "184": 1, "395": 1, "812": 1, "227": 1, "275": 1, "856": [1, 2], "76": 1, "905": 1, "67": 1, "505": 1, "739": 1, "77": 1, "971": 1, "608": 1, "277": 1, "777": 1, "713": [1, 2], "549": 1, "460": 1, "474": 1, "106": 1, "704": 1, "640": 1, "947": 1, "561": 1, "388": 1, "00e": 1, "810": 1, "56": 1, "981": 1, "576": 1, "80": [1, 8], "651": [1, 8], "69": 1, "328": 1, "775": 1, "998": 1, "300": 1, "441": 1, "042": 1, "827": 1, "837": 1, "836": 1, "558": 1, "224": 1, "709": 1, "412": 1, "291": 1, "caeel": [1, 2, 8], "01": [1, 3, 4, 5], "fr\u00e9zal": 1, "f\u00e9lix": 1, "2015": 1, "barri\u00e8r": 1, "cutter": 1, "2006": 1, "15072434": 1, "12163e": 1, "84e": 1, "ii": [1, 3], "15279421": 1, "52929e": 1, "iii": [1, 3], "13783801": 1, "9066e": 1, "iv": [1, 3], "17493829": 1, "7121e": 1, "v": [1, 3, 7, 8], "20924180": 1, "47057e": 1, "17718942": 1, "94724e": 1, "mtdna": [1, 3], "13794": 1, "05e": 1, "2009": [1, 4, 8], "advanc": [1, 8], "intercross": 1, "genotyp": [1, 8], "1454": [1, 2], "nuclear": 1, "marker": 1, "236": [1, 8], "riail": 1, "qtl": 1, "though": [1, 8], "backcross": 1, "densiti": [1, 8], "suffici": [1, 4], "high": [1, 3], "emploi": 1, "littl": 1, "tip": [1, 4], "domain": 1, "breakpoint": 1, "ce11": 1, "gca_000002985": 1, "rockman": 1, "kruglyak": 1, "1000419": 1, "canfam": [1, 4, 8], "dog": 1, "13000": [1, 3], "lindblad": 1, "toh": 1, "122678785": 1, "636e": 1, "85426708": 1, "79852e": 1, "91889043": 1, "00087e": 1, "88276631": 1, "0523e": 1, "88915250": 1, "34433e": 1, "77573801": 1, "19219e": 1, "80974532": 1, "29347e": 1, "74330416": 1, "29131e": 1, "61074082": 1, "28772e": 1, "69331447": 1, "10715e": 1, "74389097": 1, "63945e": 1, "72498081": 1, "76106e": 1, "63241923": 1, "41302e": 1, "60966679": 1, "02812e": 1, "64190966": 1, "85675e": 1, "59632846": 1, "61406e": 1, "64289059": 1, "71883e": 1, "55844845": 1, "02993e": 1, "53741614": 1, "04251e": 1, "58134056": 1, "99097e": 1, "50858623": 1, "0339e": 1, "61439934": 1, "61505e": 1, "52294480": 1, "12664e": 1, "47698779": 1, "1146e": 1, "51628933": 1, "15437e": 1, "38964690": 1, "20846e": 1, "45876710": 1, "12603e": 1, "41182112": 1, "24636e": 1, "41845238": 1, "10136e": 1, "40214260": 1, "16876e": 1, "39895921": 1, "13977e": 1, "38810281": 1, "15559e": 1, "31377067": 1, "33394e": 1, "42124431": 1, "04838e": 1, "26524999": 1, "42991e": 1, "30810995": 1, "18752e": 1, "30902991": 1, "38346e": 1, "23914537": 1, "43637e": 1, "123869142": 1, "50648e": 1, "16727": 1, "pedigre": [1, 4], "237": 1, "sex": [1, 8], "163": 1, "labrador": 1, "greyhound": 1, "shapeit2": 1, "duohmm": 1, "campbel": 1, "1534": [1, 8], "g3": 1, "116": [1, 8], "034678": 1, "chlrei": [1, 8], "001141552511415525": [1, 3], "v\u00edtov\u00e1": 1, "3999999999999998e": [1, 3], "ness": 1, "8033585": 1, "74e": 1, "9223677": 1, "62e": 1, "9219486": 1, "4091191": 1, "47e": 1, "3500558": 1, "17e": 1, "9023763": 1, "6421821": 1, "5033832": 1, "98e": 1, "7956127": 1, "6576019": 1, "97e": 1, "27e": 1, "3826814": 1, "63e": 1, "9730733": 1, "55e": 1, "5206065": 1, "56e": 1, "4157777": 1, "9e": [1, 3], "96e": 1, "1922860": 1, "93e": 1, "7783580": 1, "71e": 1, "7188315": 1, "li": 1, "1720600": [1, 3], "gene": [1, 2, 4, 5], "convers": [1, 2, 4, 5, 8], "8299999999999998": 1, "518": 1, "23513712": 1, "40463e": 1, "25286936": 1, "23459e": 1, "28110227": 1, "7966e": 1, "32079331": 1, "71642e": 1, "1348131": 1, "23542271": 1, "89651e": 1, "y": [1, 3, 7], "3667352": 1, "mitochondrion_genom": [1, 3], "19524": 1, "meios": 1, "product": 1, "lab": 1, "highli": [1, 4], "860": 1, "femal": [1, 8], "calcul": [1, 2], "detect": [1, 4], "dm6": 1, "comeron": 1, "1002905": 1, "liftover_comeron2012": [1, 4], "winlen": [1, 4], "gapthresh": [1, 4], "useadjacentavg": [1, 4], "retainintermedi": [1, 4], "african3epoch_1s16": [1, 3, 8], "outofafrica_2l06": [1, 3], "sheehan": [1, 8], "song": [1, 8], "deep": 1, "train": 1, "due": [1, 4, 8], "psmc": 1, "2n": [1, 8], "msm": 1, "4n": 1, "faithfulli": 1, "afr": [1, 8], "pcbi": 1, "1004845": 1, "refer": [1, 4, 5, 8], "700": 1, "145": [1, 8], "200": [1, 4, 8], "onset": 1, "expans": 1, "stephan": 1, "eur": [1, 8], "0020166": 1, "720": 1, "600": [1, 2], "603": 1, "075": 1, "158": 1, "diverg": [1, 4], "45e": 1, "flybas": 1, "bdgp6": 1, "cd": [1, 2, 8], "hoskin": 1, "1101": 1, "gr": 1, "185579": 1, "114": 1, "mix": 1, "1619508114": 1, "74": 1, "330": 1, "ragsdal": [1, 7], "115": 1, "184812": 1, "meanlog": 1, "sdlog": 1, "360": [1, 2], "drosec": [1, 8], "05": [1, 3, 4, 5, 8], "legrand": 1, "100000": [1, 3, 8], "24956976": 1, "21536224": 1, "51e": 1, "28131630": 1, "88e": 1, "30464902": 1, "22909512": 1, "85e": 1, "1277805": 1, "esccol": [1, 8], "805175e": [1, 3], "sezonov": 1, "2007": [1, 4], "180000000": [1, 3], "hartl": 1, "moriyama": 1, "sawyer": 1, "1994": 1, "bacteri": [1, 3, 5], "542": [1, 3], "4641652": 1, "gasacu": [1, 8], "spine": 1, "stickleback": 1, "liu": 1, "29619991": 1, "11e": [1, 8], "23686546": 1, "17759012": 1, "34181212": 1, "15550311": 1, "18825451": 1, "30776923": 1, "20553084": 1, "20843631": 1, "17985176": 1, "17651971": 1, "20694444": 1, "20748428": 1, "16147532": 1, "17318724": 1, "19507025": 1, "20195758": 1, "15939336": 1, "20580295": 1, "20445003": 1, "17421465": 1, "15859692": 1, "16543": 1, "helann": [1, 8], "strasburg": 1, "rieseberg": 1, "673968": [1, 3], "2010": [1, 4], "149502186": 1, "174800439": 1, "176490873": 1, "208320189": 1, "178169690": 1, "148147350": 1, "149542083": 1, "167167940": 1, "189665024": 1, "181411567": 1, "189830405": 1, "163781230": 1, "173487274": 1, "173346949": 1, "175671323": 1, "206736614": 1, "195042445": 1, "helmel": [1, 8], "0958904109589041": [1, 3], "pardo": 1, "diaz": 1, "2111109": [1, 3], "17206585": 1, "9045316": 1, "10541528": 1, "9662098": 1, "9908586": 1, "14054175": 1, "14308859": 1, "9320449": 1, "8708747": 1, "31e": 1, "17965481": 1, "16e": 1, "11759272": 1, "16327298": 1, "18127314": 1, "08e": 1, "9174305": 1, "10235750": 1, "78e": 1, "10083215": 1, "14773299": 1, "16803890": 1, "16399344": 1, "14871695": 1, "13359691": 1, "tremblai": 1, "v\u00e9zina": 1, "2000": [1, 3, 8], "takahata": 1, "1993": 1, "248956422": [1, 8], "15235e": 1, "29e": [1, 3, 8], "242193529": 1, "10429e": 1, "198295559": 1, "12585e": 1, "190214555": 1, "1482e": 1, "181538259": 1, "12443e": 1, "170805979": 1, "12659e": 1, "159345973": 1, "17713e": 1, "145138636": 1, "16049e": 1, "138394717": 1, "21987e": 1, "133797422": 1, "33337e": 1, "135086622": 1, "17213e": 1, "133275309": 1, "30981e": 1, "114364328": 1, "3061e": 1, "107043718": 1, "36298e": 1, "101991189": 1, "73876e": 1, "90338345": 1, "48315e": 1, "83257441": 1, "55383e": 1, "80373285": 1, "46455e": 1, "58617616": 1, "83848e": 1, "64444167": 1, "67886e": 1, "46709983": 1, "72443e": 1, "50818468": [1, 8], "10572e": 1, "156040895": 1, "18483e": 1, "57227415": 1, "16569": 1, "hapmap": [1, 4, 8], "grch37": [1, 4], "grch38": [1, 8], "decod": [1, 8], "famili": [1, 8], "pyrho": 1, "acb": [1, 2], "asw": [1, 2], "beb": [1, 2], "cdx": [1, 2], "ch": [1, 2], "clm": [1, 2], "esn": [1, 2], "fin": [1, 2], "gbr": [1, 2], "gih": [1, 2], "gwd": [1, 2], "ib": [1, 2], "itu": [1, 2], "jpt": [1, 2], "khv": [1, 2], "lwk": [1, 2], "msl": [1, 2], "mxl": [1, 2], "pel": [1, 2], "pjl": [1, 2], "pur": [1, 2], "stu": [1, 2], "tsi": [1, 2], "project": [1, 4, 7], "million": 1, "four": [1, 4, 8], "ldhat": 1, "adjust": 1, "rearrang": 1, "readm": 1, "ftp": 1, "trace": 1, "ncbi": [1, 2], "nih": 1, "gov": 1, "1000genom": 1, "technic": 1, "work": [1, 4, 6, 7, 8], "20110106_recombination_hotspot": 1, "nature06258": 1, "liftov": [1, 2, 4, 8], "liftover_catalog": [1, 4], "maintain": [1, 4, 7], "path_to_stdpopsim": 1, "chainfil": [1, 4], "path_to_chainfil": 1, "hg19tohg38": [1, 4], "chain": [1, 4], "gz": [1, 4, 8], "validationchain": [1, 4], "hg38tohg19": [1, 4], "257": [1, 8], "parent": [1, 8], "offspr": [1, 8], "pair": [1, 2, 8], "iceland": [1, 8], "289": [1, 8], "658": [1, 8], "combin": [1, 4, 8], "male": [1, 8], "com": [1, 4, 8], "addendum": [1, 8], "kong": 1, "nature09525": 1, "grch36": [1, 8], "hg18tohg38": 1, "henc": [1, 4], "separ": [1, 3, 4, 8], "infer": [1, 4, 8], "popgenmethod": 1, "smcpp": 1, "1126": [1, 4], "sciadv": 1, "aaw9206": 1, "spenc": [1, 7], "outofafricaextendedneandertaladmixturepulse_3i21": [1, 2, 3, 8], "outofafrica_2t12": [1, 2, 3, 8], "africa_1t12": [1, 3, 8], "americanadmixture_4b11": [1, 3, 8], "outofafricaarchaicadmixture_5r19": [1, 3, 8], "zigzag_1s14": [1, 2, 3, 8], "ancienteurasia_9k19": [1, 3, 8], "papuansoutofafrica_10j19": [1, 2, 3, 8], "ashksub_7g19": [1, 2, 3, 8], "outofafrica_4j17": [1, 2, 3, 8], "africa_1b08": [1, 2, 3, 8], "ancienteurope_4a21": [1, 2, 3, 8], "iasi": [1, 7], "simpl": [1, 4, 6, 8], "1a": [1, 5], "unidirect": 1, "800": 1, "ky": 1, "yoruba": [1, 4], "utah": 1, "resid": [1, 4], "ceph": 1, "northern": 1, "western": 1, "ancestri": [1, 8], "nea": 1, "msab210": 1, "029": 1, "kya": 1, "290": 1, "ooa": [1, 8], "gutenkunst": [1, 4, 7, 8], "asian": [1, 8], "maximum": [1, 4, 8], "likelihood": [1, 4, 8], "variou": [1, 2, 4, 6, 8], "han": 1, "chines": 1, "beij": 1, "china": 1, "1000695": 1, "eu": 1, "AS": 1, "510": 1, "004": 1, "0055": 1, "848": 1, "35e": [1, 8], "tennessen": 1, "analysi": [1, 2, 4, 8], "jsf": 1, "23kya": 1, "fig": 1, "s5": 1, "fu": 1, "scienc": [1, 4, 7], "1219240": 1, "nature11690": 1, "310": [1, 8], "861": 1, "032": 1, "279": 1, "501": 1, "436": 1, "432": 1, "125": 1, "00307": 1, "0195": 1, "2st": 1, "0166": [1, 8], "040": 1, "204": [1, 8], "36e": [1, 8], "tennesen": [1, 4, 8], "brown": [1, 8], "gravel": [1, 7, 8], "admix": [1, 8], "grew": [1, 8], "smaller": [1, 8], "asia": [1, 8], "1007385": 1, "1019276108": 1, "554": 1, "asn": 1, "0038": 1, "0048": 1, "emerg": 1, "percentag": 1, "amount": [1, 2, 4, 8], "popular": 1, "augment": 1, "contribut": [1, 4, 7], "eurasian": 1, "earli": 1, "put": [1, 8], "neanderth": 1, "branch": [1, 4], "symmetr": 1, "archaicafr": 1, "1008204": 1, "900": 1, "880": 1, "650": 1, "00125": 1, "00372": 1, "48": 1, "60": 1, "499": 1, "98": 1, "arch": 1, "nean": 1, "559": 1, "825": 1, "schiffel": [1, 2], "durbin": [1, 2], "terhorst": 1, "kamm": 1, "expand": [1, 7], "contract": 1, "ng": 1, "3015": 1, "560": [1, 2], "99448": 1, "00035977": 1, "0014391": 1, "005756": 1, "2rd": 1, "023025": 1, "3st": 1, "133": [1, 2], "533": 1, "333": 1, "dai": [1, 8], "momi2": 1, "input": [1, 8], "unsampl": 1, "basal": 1, "farmer": 1, "hunter": 1, "gather": 1, "sardinian": 1, "There": [1, 4, 6, 7, 8], "mbuti": 1, "addition": 1, "sever": [1, 2, 6, 8], "fossil": [1, 4], "date": [1, 3, 4, 8], "altai": 1, "prufer": 1, "mesolith": 1, "lazaridi": 1, "neolith": 1, "palaeolith": 1, "siberia": 1, "ma1": 1, "raghavan": 1, "ust": 1, "ishim": 1, "lbk": 1, "eef": 1, "loschbour": 1, "whg": 1, "upper": 1, "mal": 1, "ta": 1, "cultur": 1, "ustishim": 1, "1800": 1, "basaleurasian": 1, "1080": 1, "01621459": 1, "1635482": 1, "bazal": 1, "exp": 1, "340": 1, "696": 1, "44": [1, 4], "690": 1, "230": 1, "45": 1, "22e": 1, "ten": [1, 8], "denisovan": 1, "jacob": 1, "extens": [1, 4, 8], "malaspina": 1, "thu": [1, 4, 8], "indonesia": 1, "guinea": 1, "dena": 1, "2058": 1, "lineag": 1, "neaa": 1, "2612": 1, "den1": 1, "d1": 1, "introgress": 1, "den2": 1, "d2": 1, "nea1": 1, "1016": [1, 4], "cell": [1, 4], "02": [1, 5, 8], "035": 1, "nature18299": 1, "433": 1, "962": 1, "025": 1, "east": 1, "834": 1, "083": [1, 4], "826": [1, 2], "249": 1, "516": [1, 2], "41": 1, "563": [1, 2], "671": 1, "497": 1, "982": 1, "736": [1, 2], "64": 1, "322": [1, 8], "97": 1, "875": [1, 2], "282": 1, "750": [1, 2], "437": 1, "586": 1, "525": [1, 2], "231": 1, "243": 1, "394": [1, 2], "865": 1, "451": 1, "papaun": 1, "737": 1, "948": 1, "42": 1, "57": 1, "gladstein": [1, 7], "hammer": 1, "shown": [1, 4, 8], "mode": 1, "abc": 1, "s3": [1, 4], "ancestor": 1, "eastern": 1, "jew": 1, "experi": 1, "reduct": [1, 8], "flow": [1, 4], "arriv": 1, "group": [1, 4, 7, 8], "final": [1, 2, 4, 8], "moder": 1, "massiv": 1, "incorpor": [1, 4], "ascertain": 1, "me": 1, "waj": 1, "eaj": 1, "msz047": 1, "197": 1, "073": 1, "113": 1, "515": [1, 2], "aj": 1, "606": 1, "949": 1, "founder": 1, "105": 1, "850": [1, 8], "481": 1, "211": 1, "geneflow": 1, "jougan": 1, "joint": 1, "frequeci": 1, "af": 1, "exom": 1, "poulat": 1, "demographi": [1, 8], "previou": [1, 2, 4, 8], "japanes": 1, "program": [1, 3, 6, 7, 8], "moment": 1, "44e": 1, "tokyo": 1, "japan": 1, "117": 1, "200493": 1, "11293": 1, "23721": 1, "2831": 1, "b": [1, 3, 4, 7, 8], "2512": 1, "1019": 1, "4384": 1, "percent": 1, "8e": [1, 8], "75e": 1, "thousand": [1, 4], "357": 1, "46": 1, "boyko": [1, 8], "calibr": [1, 4, 8], "3e5": [1, 8], "chimp": [1, 8], "african_american": [1, 8], "1000083": 1, "778": 1, "636": 1, "809": 1, "80e": 1, "structur": [1, 4, 8], "demonstr": [1, 4, 8], "caucasu": 1, "anatolian": 1, "west": [1, 4], "yamnaya": 1, "stepp": 1, "rise": 1, "bronz": 1, "ag": 1, "throughout": 1, "1500": [1, 8], "ne": 1, "chg": 1, "ehg": 1, "yam": 1, "160": 1, "neo": 1, "180": 1, "135": 1, "allentoft": 1, "2022": [1, 5, 8], "04": [1, 8], "490594": 1, "140": 1, "25e": 1, "hunt": 1, "bay119": 1, "2023": [1, 7], "lethal": 1, "kim": [1, 4, 7, 8], "197145": [1, 8], "013": 1, "186": 1, "028": 1, "190": 1, "677": 1, "580": 1, "kyriazi": [1, 7, 8], "1086": 1, "726736": 1, "450": [1, 8], "010": 1, "050": 1, "inf": [1, 8], "musmu": [1, 2, 8], "mous": 1, "phifer": 1, "rixei": 1, "500000": [1, 3], "booker": 1, "keightlei": 1, "fujiwara": 1, "195154279": 1, "181755017": 1, "159745316": 1, "156860686": 1, "151758149": 1, "149588044": 1, "144995196": 1, "130127694": 1, "124359700": 1, "130530862": 1, "121973369": 1, "120092757": 1, "120883175": 1, "125139656": 1, "104073951": 1, "98008968": 1, "95294699": 1, "90720763": 1, "61420004": 1, "169476592": 1, "91455967": 1, "16299": 1, "775e": 1, "domesticuseurope_1f22": [1, 2, 3], "musculuskorea_1f22": [1, 2, 3], "castaneusindia_1f22": [1, 2, 3], "deu01": 1, "deu03": 1, "deu04": 1, "deu06": 1, "german": 1, "kazumichi": 1, "naoki": 1, "osada": 1, "graphic": [1, 4], "depict": 1, "m_musculus_domesticu": 1, "gbe": 1, "evac068": 1, "133912": 1, "98811": 1, "131050": 1, "173594": 1, "227037": 1, "279833": 1, "316861": 1, "327217": 1, "309961": 1, "271935": 1, "222951": 1, "173264": 1, "131392": 1, "101471": 1, "82953": 1, "73097": 1, "69317": 1, "69939": 1, "21th": 1, "74185": 1, "22th": 1, "81892": 1, "23th": 1, "93046": 1, "24th": 1, "107067": 1, "25th": 1, "121751": 1, "26th": 1, "132063": 1, "27th": 1, "131016": 1, "28th": 1, "115426": 1, "29th": 1, "90926": 1, "67337": 1, "31th": 1, "50557": 1, "32th": 1, "41195": 1, "33th": 1, "36886": 1, "34th": 1, "34163": 1, "35th": 1, "29931": 1, "36th": 1, "23419": 1, "37th": 1, "16490": 1, "38th": 1, "11240": 1, "39th": 1, "8332": 1, "40th": 1, "7480": 1, "41th": 1, "8463": 1, "42th": 1, "11758": 1, "43th": 1, "18939": 1, "44th": 1, "33028": 1, "45th": 1, "58488": 1, "46th": 1, "97250": 1, "47th": 1, "136620": 1, "48th": 1, "159142": 1, "49th": 1, "147212": 1, "50th": 1, "115399": 1, "51th": 1, "111242": 1, "52th": 1, "145603": 1, "53th": 1, "90428": 1, "54th": 1, "3844": 1, "55th": 1, "2040": 1, "56th": 1, "1915544": 1, "1654653": 1, "1429281": 1, "1234595": 1, "1066418": 1, "921140": 1, "795646": 1, "687237": 1, "593589": 1, "512693": 1, "442812": 1, "382446": 1, "330300": 1, "285254": 1, "246340": 1, "212726": 1, "183689": 1, "158606": 1, "136938": 1, "118221": 1, "102052": 1, "88084": 1, "76019": 1, "65596": 1, "56592": 1, "48815": 1, "42096": 1, "36292": 1, "31279": 1, "26948": 1, "23207": 1, "19975": 1, "17183": 1, "14772": 1, "12688": 1, "10889": 1, "9334": 1, "7991": 1, "6831": 1, "5829": 1, "4964": 1, "4216": 1, "3570": 1, "3012": 1, "2530": 1, "2114": 1, "1754": 1, "1443": 1, "1175": 1, "943": 1, "743": 1, "57th": 1, "kor01": 1, "kor02": 1, "kor03": 1, "kor05": 1, "korean": 1, "m_musculus_musculu": 1, "152757": 1, "407105": 1, "400867": 1, "359368": 1, "302950": 1, "245823": 1, "9thtime": 1, "194969": 1, "151909": 1, "116547": 1, "88494": 1, "67725": 1, "54304": 1, "47001": 1, "43933": 1, "43467": 1, "43874": 1, "42857": 1, "38441": 1, "30806": 1, "22556": 1, "16339": 1, "13023": 1, "12259": 1, "13588": 1, "16747": 1, "21219": 1, "25399": 1, "26648": 1, "23546": 1, "17741": 1, "12072": 1, "7990": 1, "5506": 1, "4177": 1, "3643": 1, "3751": 1, "4605": 1, "6695": 1, "11222": 1, "20382": 1, "36220": 1, "55959": 1, "68111": 1, "61935": 1, "42715": 1, "25527": 1, "16254": 1, "12104": 1, "9960": 1, "9029": 1, "8035": 1, "8931": 1, "179912": 1, "807711": 1, "697702": 1, "602670": 1, "520579": 1, "449667": 1, "388409": 1, "335491": 1, "289781": 1, "250293": 1, "216182": 1, "186716": 1, "161262": 1, "139274": 1, "120280": 1, "103872": 1, "89698": 1, "77455": 1, "66878": 1, "57741": 1, "49849": 1, "43031": 1, "37142": 1, "32054": 1, "27659": 1, "23863": 1, "20583": 1, "17750": 1, "15303": 1, "13189": 1, "11363": 1, "9785": 1, "8423": 1, "7246": 1, "6229": 1, "5350": 1, "4591": 1, "3936": 1, "3370": 1, "2881": 1, "2458": 1, "2093": 1, "1778": 1, "1505": [1, 2], "1270": 1, "1067": [1, 2], "891": 1, "740": 1, "609": 1, "495": 1, "398": [1, 2], "313": 1, "240": 1, "177": 1, "123": [1, 8], "ind03": 1, "ind04": 1, "indian": 1, "m_musculus_castaneu": 1, "castaneu": 1, "344802": 1, "463464": 1, "360433": 1, "275733": 1, "217017": 1, "182054": 1, "163295": 1, "155027": 1, "154098": 1, "159139": 1, "169657": 1, "185260": 1, "205098": 1, "227605": 1, "250544": 1, "271326": 1, "287572": 1, "297772": 1, "301783": 1, "300840": 1, "297138": 1, "293233": 1, "291560": 1, "294117": 1, "302369": 1, "317235": 1, "338818": 1, "365787": 1, "394606": 1, "418882": 1, "429975": 1, "420389": 1, "388298": 1, "338426": 1, "279816": 1, "222464": 1, "173419": 1, "134861": 1, "105533": 1, "83216": 1, "66260": 1, "53747": 1, "45372": 1, "41297": 1, "41845": 1, "47736": 1, "60911": 1, "86633": 1, "141377": 1, "291323": 1, "938111": 1, "5064712": 1, "64853": 1, "5585000": 1, "4955842": 1, "4397456": 1, "3901912": 1, "3462105": 1, "3071789": 1, "2725404": 1, "2417965": 1, "2145140": 1, "1903000": 1, "1688102": 1, "1497384": 1, "1328123": 1, "1177907": 1, "1044593": 1, "926277": 1, "821274": 1, "728084": 1, "645379": 1, "571979": 1, "506839": 1, "449026": 1, "397719": 1, "352184": 1, "311772": 1, "275907": 1, "244079": 1, "215830": 1, "190760": 1, "168510": 1, "148764": 1, "131239": 1, "115687": 1, "101884": 1, "89634": 1, "78762": 1, "69114": 1, "60551": 1, "52951": 1, "46207": 1, "40221": 1, "34909": 1, "30195": 1, "26011": 1, "22297": 1, "19002": 1, "16077": 1, "13481": 1, "11178": 1, "9133": 1, "7319": 1, "5709": 1, "4279": 1, "3011": 1, "1886": 1, "887": 1, "orysat": [1, 2, 8], "caicedo": 1, "46875": [1, 3], "43270923": 1, "490520": 1, "134525": 1, "35937250": 1, "36413819": 1, "35502694": 1, "29958434": 1, "31248787": 1, "29697621": 1, "28443022": 1, "23012720": 1, "23207287": 1, "29021106": 1, "27531856": 1, "bottleneckmigration_3c07": [1, 2, 3], "indica": 1, "tropic": 1, "japonica": 1, "ruf": 1, "rufipogon": 1, "ind": [1, 8], "trj": 1, "0030163": 1, "150": 1, "partial": [1, 4], "recoveri": 1, "pantro": [1, 2, 8], "chimpanze": 1, "langergrab": 1, "16781": [1, 3], "stevison": 1, "228573443": 1, "2a": [1, 3], "111504155": 1, "2b": [1, 3], "133216015": 1, "202621043": 1, "194502333": 1, "181907262": 1, "175400573": 1, "166211670": 1, "147911612": 1, "116767853": 1, "135926727": 1, "135753878": 1, "137163284": 1, "100452976": 1, "91965084": 1, "83230942": 1, "81586097": 1, "83181570": 1, "78221452": 1, "61309027": 1, "66533130": 1, "33445071": 1, "37823149": 1, "155549662": 1, "26350515": 1, "bonoboghost_4k19": [1, 2, 3], "kuhlwilm": [1, 2], "row": 1, "central": [1, 4], "extinct": 1, "among": [1, 4], "populatio": 1, "s41559": 1, "0881": 1, "11600": 1, "10200": 1, "3700": 1, "24900": 1, "8000": 1, "29100": 1, "65900": 1, "9200": 1, "015": 1, "005": 1, "3500": [1, 3], "1990": 1, "1200": [1, 2], "stop": [1, 4], "379": 1, "resiz": 1, "308": 1, "261": 1, "papanu": [1, 2, 8], "oliv": 1, "baboon": 1, "wu": 1, "335505": [1, 3], "wall": 1, "218172882": 1, "92638e": 1, "193660750": 1, "60544e": 1, "184919515": 1, "02238e": 1, "182120902": 1, "82513e": 1, "173900761": 1, "5798e": 1, "167138247": 1, "04979e": 1, "161768468": 1, "11888e": 1, "140274886": 1, "10899e": 1, "127591819": 1, "13288e": 1, "126462689": 1, "17532e": 1, "125913696": 1, "18403e": 1, "123343450": 1, "0824e": 1, "106849001": 1, "24677e": 1, "106654974": 1, "27419e": 1, "91985775": 1, "26084e": 1, "91184193": 1, "47616e": 1, "74525926": 1, "5241e": 1, "72894408": 1, "36841e": 1, "72123344": 1, "30374e": 1, "50021108": 1, "6772e": 1, "142711496": 1, "18898e": 1, "8309886": 1, "coloni": 1, "hous": [1, 4], "southwest": 1, "nation": 1, "primat": 1, "research": [1, 4], "center": 1, "snprc": 1, "evac040": 1, "singlepopsmcpp_1w22": [1, 2, 3], "panubis_snprc": 1, "93362": 1, "55968": 1, "72998": 1, "30714": 1, "41841": 1, "51822": 1, "120758": 1, "2046585": 1, "1219140": 1, "782017": 1, "432614": 1, "165305": 1, "5101": 1, "2434": 1, "phosin": [1, 2, 8], "robinson": 1, "taylor": 1, "185845356": 1, "178563925": 1, "174291665": 1, "146127150": 1, "139762554": 1, "115952311": 1, "115469292": 1, "110408561": 1, "106736052": 1, "102828027": 1, "104118372": 1, "90399378": 1, "90400161": 1, "89762611": 1, "88287594": 1, "85252673": 1, "79603858": 1, "79885847": 1, "59501331": 1, "58878645": 1, "35802323": 1, "131664873": 1, "vaquita2epoch_1r22": [1, 2, 3, 8], "evolv": 1, "kb": [1, 8], "did": [1, 4], "cpg": 1, "island": 1, "coverag": [1, 5], "60x": 1, "supp": 1, "s2": 1, "n_anc": 1, "n_curr": 1, "abm1742": 1, "807": 1, "162": 1, "morin": 1, "pipelin": [1, 4], "1755": 1, "0998": 1, "13284": 1, "026": 1, "ponab": [1, 8], "sumatran": 1, "wich": 1, "17900": [1, 3], "lock": 1, "227913704": 1, "72097e": 1, "109511694": 1, "74694e": 1, "129937803": 1, "08833e": 1, "193656255": 1, "77615e": 1, "189387572": 1, "06176e": 1, "179185813": 1, "87839e": 1, "169501136": 1, "89605e": 1, "145408105": 1, "82979e": 1, "144036388": 1, "34313e": 1, "112206110": 1, "04756e": 1, "132178492": 1, "94812e": 1, "128122151": 1, "79185e": 1, "132184051": 1, "04316e": 1, "98475126": 1, "40817e": 1, "88963417": 1, "11075e": 1, "82547911": 1, "6315e": 1, "68237989": 1, "76066e": 1, "75914007": 1, "01983e": 1, "75923960": 1, "40065e": 1, "57575784": 1, "09647e": 1, "60841859": 1, "31424e": 1, "34683425": 1, "58867e": 1, "35308119": 1, "83628e": 1, "151242693": 1, "40288e": 1, "16499": 1, "nater": 1, "pygmaeu": 1, "cub": 1, "047": 1, "ponabe2": 1, "ponabe3": 1, "bornean": 1, "twospecies_2l11": [1, 3], "decai": [1, 8], "grow": [1, 2, 8], "slightli": [1, 4, 8], "nature09687": 1, "934": 1, "617": 1, "317": 1, "805": 1, "157": 1, "straga": [1, 8], "0027397260273972603": [1, 3], "savageau": 1, "1983": 1, "140000": [1, 3], "da": 1, "cunha": 1, "120000": [1, 3], "2065074": 1, "53e": [1, 3], "offer": 1, "updat": [2, 4, 6], "activ": [2, 4, 6, 8], "error": [2, 4, 6, 8], "gamma_k17": [2, 3, 4, 8], "dfe": [2, 3, 5], "ryangutenkunst": 2, "1478": 2, "engin": [2, 3, 4, 5, 6], "led": 2, "declin": 2, "small": [2, 4, 8], "model": [2, 3, 5, 7], "petrelharp": 2, "1622": 2, "time_unit": 2, "now": [2, 4, 8], "gener": [2, 3, 4, 5, 7], "avoid": 2, "mismatch": 2, "nspope": 2, "1567": 2, "As": [2, 4, 7, 8], "behavior": 2, "original_coordin": 2, "basic_contig": 2, "deprec": 2, "1570": 2, "might": [2, 4, 8], "underli": 2, "top": [2, 4, 8], "level": [2, 4, 6, 8], "affect": [2, 4, 8], "anyon": [2, 8], "who": [2, 4, 7], "pars": [2, 4], "relat": [2, 4, 8], "sweep": [2, 5], "infrastructur": [2, 4], "move": 2, "namespac": 2, "proper": 2, "featur": [2, 4, 7, 8], "1498": 2, "mu": [2, 3, 5, 8], "musculu": [2, 3, 5, 8], "peterdfield": 2, "1437": 2, "igronau": 2, "orzya": 2, "sativa": [2, 3, 5, 8], "ornobalam": 2, "1453": 2, "minesrebollo": 2, "1461": 2, "phocoena": [2, 3, 5], "sinu": [2, 3, 5], "1514": 2, "ckyriazi": 2, "1538": 2, "lognormal_h17": [2, 3], "1480": 2, "mixed_k23": [2, 3, 8], "chriscrsmith": 2, "gamma_r22": [2, 3], "1547": 2, "1560": 2, "1492": 2, "demograph": [2, 3, 5, 7], "1485": 2, "1531": 2, "1524": 2, "1526": 2, "1520": 2, "releas": [2, 5], "grahamgow": 2, "chr4": [2, 3, 8], "izabelcavassim": 2, "1092": 2, "incorrectli": 2, "1345": 2, "api": [2, 3, 4, 5], "jeromekelleh": [2, 4], "old": 2, "1361": 2, "aed": [2, 3, 5, 8], "aegypti": [2, 3, 4, 5, 8], "manolofperez": 2, "871": 2, "893": 2, "ana": [2, 3, 5, 8], "platyrhyncho": [2, 3, 5, 8], "1070": 2, "anoli": [2, 3, 5, 8], "carolinensi": [2, 3, 5, 8], "vcaudil": 2, "874": 2, "andrewkern": [2, 4], "896": 2, "anophel": [2, 3, 5, 8], "gambia": [2, 3, 5, 8], "906": 2, "mellifera": [2, 3, 5, 8], "janaobstet": 2, "1025": 2, "1268": 2, "bo": [2, 3, 5, 8], "tauru": [2, 3, 5, 8], "gtsambo": 2, "1269": 2, "caenorhabd": [2, 3, 5, 8], "elegan": [2, 3, 5, 8], "attrna": 2, "910": 2, "1265": 2, "chlamydomona": [2, 3, 5, 8], "reinhardtii": [2, 3, 5, 8], "aai": 2, "drosophila": [2, 3, 5], "sechellia": [2, 3, 5, 8], "jradrion": 2, "872": 2, "vitorpavinato": 2, "1264": 2, "gasterosteu": [2, 3, 5, 8], "aculeatu": [2, 3, 5, 8], "1105": 2, "1253": 2, "helianthu": [2, 3, 5, 8], "annuu": [2, 3, 5, 8], "1218": 2, "xin": [2, 7], "huang": [2, 7], "1250": 2, "heliconiu": [2, 3, 5, 8], "melpomen": [2, 3, 5, 8], "percyf": 2, "870": 2, "noscod": 2, "1165": 2, "pan": [2, 3, 5], "troglodyt": [2, 3, 5], "1215": 2, "1291": 2, "papio": [2, 3, 5], "anubi": [2, 3, 5], "saurabhbelsar": 2, "1216": 2, "mufernando": 2, "1263": 2, "streptococcu": [2, 3, 5], "agalactia": [2, 3, 5], "jeanrjc": 2, "854": 2, "1251": 2, "883": 2, "1021": [2, 8], "1279": 2, "1272": 2, "leonardolasi": 2, "1066": 2, "awohn": 2, "1259": 2, "rwapl": 2, "jeffspenc": 2, "1246": 2, "993": 2, "995": 2, "alipearson": 2, "941": 2, "1256": 2, "1370": 2, "1261": 2, "rockmanriail_ce11": [2, 3], "comeroncrossoverv2_dm6": [2, 3, 4], "592": 2, "hapmapii_grch38": [2, 3, 8], "1301": 2, "decodesexaveraged_grch38": [2, 3, 8], "pyrhoxxx_grch38": 2, "572": 2, "575": 2, "xxx": 2, "pyrho_panubis1_0": [2, 3], "1002": 2, "plu": 2, "930": [2, 8], "1152": 2, "462": 2, "1341": 2, "fbaumdick": 2, "1106": 2, "1355": 2, "apragsdal": 2, "664": 2, "arbitrari": [2, 8], "1348": 2, "keyword": [2, 7], "764": 2, "1326": 2, "839": 2, "1356": 2, "messag": [2, 3, 4], "cli": [2, 5], "equival": [2, 8], "still": [2, 4, 8], "rais": [2, 8], "help": [2, 3, 4, 7, 8], "1052": 2, "1117": 2, "qualiti": [2, 3, 4], "1292": 2, "pull": [2, 4, 7], "autom": [2, 4], "790": 2, "templat": [2, 4], "772": 2, "tool": [2, 8], "574": 2, "araport_11": 2, "1327": 2, "flybase_bdgp6": [2, 3], "32": [2, 3], "1042": 2, "ensembl_havana_104": 2, "gamma_h17": [2, 3], "1046": [2, 8], "lognormalpluspositive_r16": [2, 3], "1178": 2, "1099": 2, "import": [2, 4, 8], "bugfix": 2, "recommend": [2, 4, 6], "signific": 2, "repeat": 2, "analys": [2, 4, 5], "correct": 2, "off": [2, 4], "african": [2, 8], "european": [2, 8], "continu": [2, 4], "ancient": [2, 8], "period": [2, 8], "496": 2, "ndukler": 2, "527": 2, "requir": [2, 3, 4, 5, 8], "attr": 2, "399": 2, "cani": [2, 3, 5, 8], "familiari": [2, 3, 5, 8], "375": 2, "pongo": [2, 3, 4, 5], "abelii": [2, 3, 5], "363": 2, "372": 2, "387": 2, "agladstein": 2, "494": 2, "536": 2, "409": 2, "392": 2, "407": 2, "aw": [2, 4], "514": 2, "335": [2, 8], "477": 2, "quiet": [2, 3], "q": [2, 3, 8], "chrm": [2, 3], "528": 2, "405": 2, "temporarili": 2, "ponpyg": 2, "pin": 2, "packag": [2, 4, 6, 8], "problem": [2, 4], "366": 2, "jgallowa07": 2, "359": 2, "multi": [2, 4], "365": 2, "cache_dir": [3, 8], "subcommand": 3, "exit": 3, "essenti": [3, 4, 8], "dir": [3, 4], "environ": [3, 6, 7, 8], "stdpopsim_cach": 3, "home": 3, "runner": 3, "binari": [3, 6, 8], "redirect": [3, 8], "filenam": [3, 4, 8], "782e": 3, "help_model": [3, 8], "bibtex_fil": [3, 8], "l": [3, 7, 8], "accept": 3, "depend": [3, 6], "bib": 3, "overwrit": 3, "dry": [3, 8], "actual": [3, 8], "chr1": [3, 4, 8], "chr2": 3, "chr3": 3, "leftmost": 3, "rightmost": 3, "automat": [3, 4, 6, 8], "anyth": [3, 8], "comma": 3, "433e": 3, "chr5": 3, "chr6": 3, "chr7": 3, "chr8": 3, "chr9": 3, "chr10": 3, "chr11": 3, "chr12": 3, "chr13": 3, "chr14": 3, "chr15": 3, "chr16": 3, "chr17": 3, "chr18": 3, "chr19": 3, "chr20": [3, 8], "chr21": 3, "chr23": 3, "chr24": 3, "chr25": 3, "chr26": 3, "chr27": 3, "chr28": 3, "chr29": 3, "chr30": 3, "chrz": 3, "chr31": 3, "chr32": 3, "chr33": 3, "chr34": 3, "chr35": 3, "chr36": 3, "chr37": 3, "chr38": 3, "chr39": 3, "chr40": 3, "447e": 3, "chr2l": [3, 4, 8], "chr2r": 3, "chr3l": 3, "chr3r": 3, "chrx": 3, "318e": 3, "nc_037638": 3, "nc_037639": 3, "nc_037640": 3, "nc_037641": 3, "nc_037642": 3, "nc_037643": 3, "nc_037644": 3, "nc_037645": 3, "nc_037646": 3, "nc_037647": 3, "nc_037648": 3, "nc_037649": 3, "nc_037650": 3, "nc_037651": 3, "nc_037652": 3, "nc_037653": 3, "nc_001566": 3, "arabidopsi": [3, 4, 5, 8], "thaliana": [3, 4, 5, 8], "029e": 3, "help_genetic_map": [3, 8], "help_df": [3, 8], "help_annot": [3, 8], "salomeaveraged_tair10": [3, 4, 8], "popsim": [3, 4, 7], "io": 3, "doc": 3, "html": [3, 4], "gamma_h18": 3, "araport_11_exon": 3, "araport_11_cd": 3, "854e": 3, "053e": 3, "506e": 3, "campbell2016_canfam3_1": 3, "351e": 3, "459e": 3, "melanogast": [3, 4, 5], "085e": 3, "comeroncrossover_dm6": 3, "chry": 3, "51_exon": 3, "51_cd": 3, "223e": 3, "escherichia": [3, 5, 8], "001e": 3, "966e": 3, "253e": 3, "hapmapii_grch37": [3, 4], "decodesexaveraged_grch36": [3, 8], "pyrhoacb_grch38": 3, "pyrhoasw_grch38": 3, "pyrhobeb_grch38": 3, "pyrhocdx_grch38": 3, "pyrhoceu_grch38": 3, "pyrhochb_grch38": 3, "pyrhochs_grch38": 3, "pyrhoclm_grch38": 3, "pyrhoesn_grch38": 3, "pyrhofin_grch38": 3, "pyrhogbr_grch38": 3, "pyrhogih_grch38": 3, "pyrhogwd_grch38": 3, "pyrhoibs_grch38": 3, "pyrhoitu_grch38": 3, "pyrhojpt_grch38": 3, "pyrhokhv_grch38": 3, "pyrholwk_grch38": 3, "pyrhomsl_grch38": 3, "pyrhomxl_grch38": 3, "pyrhopel_grch38": 3, "pyrhopjl_grch38": 3, "pyrhopur_grch38": 3, "pyrhostu_grch38": 3, "pyrhotsi_grch38": 3, "pyrhoyri_grch38": 3, "ensembl_havana_104_exon": [3, 8], "ensembl_havana_104_cd": [3, 8], "567e": 3, "oryza": [3, 5, 8], "955e": 3, "chr2a": 3, "chr2b": 3, "124e": 3, "phocoena_sinu": 3, "mphosin1": 3, "pri": 3, "110_exon": 3, "110_cd": 3, "403e": 3, "naterpa_ponabe3": 3, "naterpp_ponabe3": 3, "them": [3, 4, 8], "alreadi": [3, 4, 8], "effort": [4, 7], "welcom": [4, 7], "envis": 4, "contributor": [4, 7], "curat": 4, "biologist": 4, "great": [4, 8], "step": [4, 5, 8], "ins": 4, "establish": 4, "benchmark": [4, 7], "align": 4, "goal": [4, 7], "confus": 4, "edit": [4, 8], "contact": [4, 7], "subscrib": [4, 7], "email": [4, 7], "serv": [4, 7], "comment": [4, 7], "lot": [4, 7, 8], "chatter": [4, 7], "ve": [4, 7, 8], "cooper": [4, 7], "want": [4, 8], "don": 4, "look": [4, 8], "good": [4, 8], "And": [4, 8], "importantli": 4, "conduct": [4, 7], "sure": [4, 6, 8], "fork": 4, "repo": 4, "clone": 4, "instruct": [4, 6], "librari": [4, 6, 7, 8], "later": [4, 6, 8], "pip": [4, 5], "python3": [4, 6], "txt": 4, "conda": [4, 5], "forg": [4, 6], "channel": [4, 6], "config": [4, 6], "troubl": 4, "try": [4, 6, 8], "pip3": 4, "encourag": [4, 7], "venv": 4, "stdpopsim_env": 4, "next": [4, 8], "bin": 4, "prompt": 4, "deactiv": 4, "repositori": 4, "copi": [4, 8], "hook": 4, "upstream": 4, "remot": 4, "topic": 4, "reliabl": [4, 6], "recip": 4, "git": 4, "fetch": 4, "checkout": 4, "topic_branch_nam": 4, "re": [4, 8], "open": [4, 7, 8], "gotten": 4, "On": [4, 8], "violat": 4, "style": 4, "find": [4, 7, 8], "reformat": 4, "modifi": [4, 8], "made": [4, 8], "stage": 4, "unstag": 4, "bypass": 4, "feedback": 4, "progress": 4, "verifi": [4, 8], "basic": [4, 6, 8], "task": [4, 8], "messi": 4, "clean": 4, "squash": 4, "visualis": 4, "network": [4, 7], "view": 4, "let": [4, 8], "graph": [4, 8], "decor": 4, "onelin": 4, "someth": [4, 8], "923ab2": 4, "mcveanlab": 4, "0190a92": 4, "2a5fc09": 4, "outlin": 4, "1ccb970": 4, "c49601f": 4, "better": 4, "fab9310": 4, "62c9560": 4, "tidi": 4, "51e21e8": 4, "6fff557": 4, "modul": [4, 5], "90d6367": 4, "concept": 4, "e2aaf95": 4, "debug": 4, "info": [4, 8], "2fbdfdc": 4, "badg": 4, "circleci": 4, "codecov": 4, "c66b575": 4, "ci": 4, "3ae454f": 4, "circl": 4, "c39415a": 4, "dd47000": 4, "recomb": 4, "nice": 4, "linear": 4, "consist": 4, "meaning": 4, "ideal": 4, "aim": 4, "achiev": [4, 8], "rewrit": 4, "never": 4, "caus": 4, "idea": [4, 8], "bisect": 4, "easier": [4, 7, 8], "nois": 4, "97a9458": 4, "c9c4a28": 4, "ad4c807": 4, "0fe6dc4": 4, "520e6ac": 4, "20fb835": 4, "port": 4, "tennyson": 4, "b3d45ea": 4, "quickli": [4, 8], "79d26b4": 4, "fly_model": 4, "doesn": [4, 8], "against": 4, "interact": 4, "editor": [4, 7], "pick": 4, "onto": 4, "p": [4, 7, 8], "reword": 4, "amend": 4, "meld": 4, "fixup": 4, "discard": 4, "exec": 4, "shell": 4, "drop": 4, "bottom": 4, "THAT": 4, "WILL": 4, "BE": 4, "everyth": 4, "abort": 4, "success": 4, "screen": 4, "enter": 4, "tue": 4, "mar": 4, "00": 4, "0000": 4, "No": [4, 8], "rst": 4, "delet": 4, "session": [4, 8], "detach": 4, "6b8a2a5": 4, "insert": [4, 8], "successfulli": 4, "ref": [4, 8], "forc": 4, "push": 4, "mislead": 4, "fast": [4, 8], "fail": 4, "hint": 4, "behind": 4, "counterpart": 4, "integr": 4, "again": [4, 8], "NOT": 4, "listen": 4, "TO": 4, "IN": 4, "terribl": 4, "advic": 4, "mess": [4, 8], "replac": 4, "state": [4, 8], "delta": 4, "thread": 4, "kib": 4, "mib": 4, "reus": 4, "d033ffa": 4, "ok": 4, "just": [4, 8], "sometim": [4, 8], "frustrat": 4, "loop": 4, "undo": [4, 8], "explan": 4, "go": [4, 8], "topic_branch": 4, "a3": 4, "realli": 4, "pain": 4, "togeth": [4, 7], "said": 4, "irrevers": 4, "backup": 4, "topic_backup": 4, "diff": [4, 8], "diagram": 4, "patch": 4, "root": [4, 8], "fresh": 4, "test_branch": 4, "p1": 4, "reset": 4, "revers": 4, "oper": 4, "noth": 4, "bad": 4, "facilit": 4, "divers": [4, 7, 8], "That": 4, "certain": [4, 6, 8], "everi": [4, 8], "unsur": 4, "baselin": 4, "think": [4, 8], "discuss": [4, 8], "fill": 4, "solut": 4, "characterist": 4, "Of": [4, 8], "cours": [4, 8], "precis": 4, "practic": [4, 7, 8], "guidelin": 4, "compon": 4, "brief": 4, "action": [4, 7], "incomplet": [4, 7], "scaffold": 4, "accumul": 4, "compar": [4, 8], "phylogenet": 4, "variat": [4, 8], "direct": 4, "hopefulli": 4, "fine": 4, "vari": [4, 7, 8], "nonetheless": [4, 8], "furthermor": [4, 8], "histor": 4, "captur": [4, 8], "presenc": 4, "natur": 4, "knowledg": 4, "typic": 4, "mention": 4, "question": 4, "assist": 4, "member": [4, 7], "brows": 4, "hesit": 4, "happi": 4, "answer": 4, "relev": [4, 8], "subdirectori": 4, "devot": 4, "six": 4, "charact": 4, "unless": 4, "explicitli": 4, "util": 4, "_": [4, 8], "arabidopsis_thaliana": 4, "insid": 4, "species_id": 4, "__init__": 4, "load": [4, 8], "physic": 4, "slot": 4, "probabl": [4, 8], "accompani": 4, "test_": 4, "summar": 4, "_genom": 4, "_speci": 4, "1000genomesconsortium": 4, "webpag": 4, "citereason": 4, "rec_rat": 4, "mut_rat": 4, "pop_siz": 4, "gen_tim": 4, "auxiliari": 4, "mitochondri": 4, "plastid": 4, "chromsoom": 4, "mbe": 4, "_rho": 4, "1e6": [4, 8], "_ne": 4, "124000": 4, "_mean_recombination_r": 4, "_recombination_r": 4, "ossowski": 4, "_mean_mutation_r": 4, "_mutation_r": 4, "_species_ploidi": 4, "_ploidi": 4, "1180677": 4, "msu247": 4, "nar": 4, "gkm965": 4, "swarbreck": 4, "10_000": 4, "1890": 4, "0012": 4, "9658": 4, "1006": 4, "gtinso": 4, "co": 4, "2016": [4, 8], "063": 4, "newli": [4, 8], "pytest": 4, "blank": 4, "disabl": [4, 8], "someon": 4, "els": [4, 8], "offici": 4, "team": 4, "undergo": 4, "fulli": [4, 6, 8], "stai": [4, 8], "tune": 4, "settl": 4, "discrep": 4, "whenev": 4, "core": 4, "meet": 4, "consid": 4, "provision": 4, "simpli": [4, 8], "press": 4, "purpos": [4, 8], "consider": 4, "checklist": 4, "volunt": 4, "intent": 4, "duplic": 4, "partit": 4, "aspect": [4, 8], "examin": 4, "involv": [4, 5], "understand": [4, 8], "uncertain": 4, "inconsist": 4, "confid": 4, "choos": 4, "blind": 4, "interpret": 4, "reach": [4, 8], "agreement": 4, "ambigu": 4, "decis": 4, "clearli": 4, "accordingli": 4, "rational": [4, 8], "consensu": 4, "block": 4, "recal": [4, 8], "skip": 4, "yet": [4, 8], "parametr": 4, "def": 4, "test_recombination_r": 4, "self": 4, "assert": 4, "approx": 4, "kei": 4, "test_aedaeg": 4, "306e": 4, "249e": 4, "291e": 4, "invok": 4, "misspecif": 4, "unrealist": 4, "downstream": [4, 8], "clear": 4, "seri": 4, "primarili": 4, "suggest": 4, "decid": [4, 8], "special": 4, "add_demographic_model": 4, "_model_func_nam": 4, "population_configur": 4, "migration_matrix": 4, "demographic_ev": 4, "eleven": 4, "eight": 4, "quit": [4, 8], "straightforward": [4, 8], "hand": 4, "camel": 4, "underscor": 4, "textual": 4, "paragraph": 4, "panel": 4, "yoruban": 4, "cite": [4, 7], "dem_model": 4, "bake": 4, "uncommon": 4, "specifc": 4, "ratio": [4, 8], "admixtur": [4, 8], "plausibl": [4, 8], "posterior": 4, "parameter_t": 4, "model_id": 4, "csv": 4, "properli": 4, "_build": 4, "confirm": 4, "okai": 4, "statement": 4, "parallel": 4, "_model_id_": 4, "_your_review_funct": 4, "term": [4, 7, 8], "enough": [4, 8], "slow": 4, "upload": 4, "delimit": 4, "programat": 4, "definit": [4, 5], "exactli": [4, 8], "32807": 4, "016134": 4, "488426": 4, "579949": 4, "tar": 4, "gzip": [4, 8], "archiv": 4, "tarbal": 4, "flat": [4, 8], "sent": 4, "placement": 4, "cloud": 4, "approv": 4, "_genetic_map_cit": 4, "fill_m": 4, "9999": 4, "gen_map": 4, "field": 4, "_gm": 4, "amazonaw": 4, "name_": 4, "_more_nam": 4, "add_genetic_map": 4, "sha256sum": 4, "gnu": 4, "coreutil": 4, "tgz": 4, "wait": 4, "whom": 4, "send": 4, "andrew": [4, 7], "kern": [4, 7], "him": 4, "hardcod": 4, "receiv": 4, "expect": [4, 8], "resourc": [4, 8], "filename_v1": 4, "whatev": 4, "increment": 4, "remap": 4, "hg19": 4, "window": [4, 6, 8], "threshold": 4, "gap": 4, "adjac": 4, "usechromosomeavg": 4, "plot": 4, "liftover_valid": 4, "intermedi": 4, "inspect": 4, "liftover_intermedi": 4, "retaininermedi": 4, "deem": 4, "proce": 4, "albeit": 4, "minimap2": 4, "paftool": 4, "js": 4, "_dfe_func_nam": 4, "accord": 4, "0004": 4, "distributoin": 4, "p_neutral": 4, "p_neg": 4, "299": 4, "p_posit": 4, "finish": 4, "convinc": [4, 8], "potenti": [4, 8], "er": 4, "readabl": 4, "pep8": 4, "guid": 4, "89": 4, "suit": 4, "strict": 4, "first_3_letters_genu": 4, "first_3_letters_speci": 4, "capitil": 4, "familiar": 4, "camelcasedescriptivenam": 4, "somethingdescript": 4, "number_of_popul": 4, "first_author_initi": 4, "two_digit_d": 4, "meant": 4, "crash": 4, "etc": [4, 8], "necessarili": 4, "collis": 4, "similarli": 4, "first_authors_last_name_first_lett": 4, "sens": [4, 8], "few": [4, 8], "power": 4, "flake8": 4, "permit": 4, "whitespac": 4, "offend": 4, "renam": 4, "cov": 4, "straightfoward": 4, "web": 4, "htmlcov": 4, "highlight": 4, "red": 4, "restructuredtext": 4, "markup": 4, "sphinx": 4, "changelog": [4, 5], "ui": 4, "sdist": 4, "setuptools_scm": 4, "appopri": 4, "pypi": 4, "twine": 4, "dist": 4, "tag": 4, "symlink": 4, "feedstock": 4, "introduct": [5, 8], "licenc": 5, "instal": [5, 7, 8], "quick": [5, 8], "workflow": 5, "standard": [5, 7], "2024": 5, "06": [5, 7, 8], "search": [5, 8], "awai": [6, 8], "jupyt": 6, "binder": 6, "particularli": [6, 8], "osx": 6, "linux": 6, "miniconda": 6, "anaconda": 6, "virtual": 6, "compil": 6, "guarante": 6, "regular": 6, "unix": 6, "dataset": 7, "hood": 7, "reli": [7, 8], "skim": [7, 8], "softwar": 7, "scientist": 7, "especi": 7, "underrepres": 7, "popgen": 7, "largest": 7, "commit": 7, "friendli": 7, "safe": [7, 8], "gender": 7, "sexual": 7, "orient": 7, "abil": [7, 8], "ethnic": 7, "socioeconom": 7, "statu": 7, "religion": 7, "lack": 7, "thereof": 7, "Being": 7, "valuabl": 7, "avenu": 7, "career": 7, "manuscript": 7, "followup": 7, "jeffrei": 7, "adrion": 7, "christoph": 7, "cole": 7, "noah": 7, "dukler": 7, "jare": 7, "gallowai": 7, "ariella": 7, "graham": 7, "gower": 7, "aaron": 7, "georgia": 7, "tsambo": 7, "franz": 7, "baumdick": 7, "jedidiah": 7, "carlson": 7, "reed": 7, "cartwright": 7, "arun": 7, "ilan": 7, "gronau": 7, "bernard": 7, "patrick": 7, "mckenzi": 7, "philipp": 7, "messer": 7, "ekaterina": 7, "noskova": 7, "diego": 7, "ortega": 7, "del": 7, "vecchyo": 7, "fernando": 7, "racimo": 7, "travi": 7, "struck": 7, "simon": 7, "ryan": 7, "kirk": 7, "lohmeul": 7, "peter": 7, "ralph": 7, "daniel": 7, "schrider": 7, "adam": 7, "siepel": 7, "jerom": 7, "kelleh": 7, "elif": 7, "e54967": 7, "7554": 7, "54967": 7, "elis": 7, "lauterbur": 7, "maria": 7, "izabel": 7, "cavassim": 7, "nathaniel": 7, "pope": 7, "jeff": 7, "saurabh": 7, "belsar": 7, "arjun": 7, "biddanda": 7, "victoria": 7, "caudil": 7, "jean": 7, "curi": 7, "ignacio": 7, "echevarria": 7, "benjamin": 7, "haller": 7, "ahm": 7, "hasan": 7, "leonardo": 7, "nicola": 7, "martin": 7, "jana": 7, "ob\u0161tet": 7, "vitor": 7, "antonio": 7, "corr\u00eaa": 7, "pavinato": 7, "alic": 7, "pearson": 7, "david": 7, "peed": 7, "manolo": 7, "perez": 7, "murillo": 7, "rodrigu": 7, "chri": 7, "smith": 7, "anastasia": 7, "teterina": 7, "sila": 7, "titt": 7, "unneberg": 7, "juan": 7, "manuel": 7, "vazquez": 7, "wapl": 7, "anthoni": 7, "wilder": 7, "wohn": 7, "yan": 7, "wong": 7, "gregor": 7, "gorjanc": 7, "lesson": 7, "realist": [7, 8], "rp84874": 7, "84874": 7, "articl": 7, "article_typ": 7, "titl": [7, 8], "lohmuel": 7, "coop": 7, "wittkopp": 7, "patricia": 7, "novembr": 7, "john": 7, "sethuraman": 7, "mathieson": 7, "sara": 7, "volum": 7, "month": 7, "jun": 7, "pub_dat": 7, "issn": 7, "2050": 7, "084x": 7, "ltd": 7, "ob": 7, "teter": 7, "corr": 7, "gplv3": 7, "licens": 7, "complic": 8, "walk": 8, "nest": 8, "context": 8, "trait": 8, "seen": 8, "foo": 8, "syntax": 8, "rememb": 8, "termin": 8, "truncat": 8, "american": 8, "10000000": 8, "20000000": 8, "scenario": 8, "compact": 8, "effici": 8, "genealog": 8, "analyz": 8, "pretti": 8, "fifti": 8, "ls": 8, "lth": 8, "rw": 8, "natep": 8, "6g": 8, "oct": 8, "03": 8, "163m": 8, "zip": 8, "tszip": 8, "reduc": 8, "49m": 8, "tsz": 8, "103m": 8, "swap": 8, "didn": 8, "big": 8, "unlik": 8, "minut": 8, "whera": 8, "upward": 8, "briefli": 8, "speedup": 8, "accomplish": 8, "drift": 8, "disequilibrium": 8, "faster": 8, "fewer": 8, "seem": 8, "indistinguish": 8, "awar": 8, "subtl": 8, "urrichio": 8, "hernandez": 8, "conver": 8, "bundl": 8, "ex": 8, "cat": 8, "14500000": 8, "15000000": 8, "30002425": 8, "30002430": 8, "30003000": 8, "14001000": 8, "14005000": 8, "suppli": 8, "silent": 8, "perus": 8, "arm": 8, "extrem": 8, "nervou": 8, "prepend": 8, "vv": 8, "helpfulli": 8, "grep": 8, "2214454132353": 8, "runinitializecallback": 8, "initializemutationtyp": 8, "initializegenomicelementtyp": 8, "m0": 8, "initializegenomicel": 8, "g0": 8, "999999": 8, "initializemutationr": 8, "initializetreeseq": 8, "initializerecombinationr": 8, "40457e": 8, "tick": 8, "sim": 8, "addsubpop": 8, "6521": 8, "p0": 8, "setsubpopulations": 8, "8521": 8, "8721": 8, "sampleindividu": 8, "treeseqrememberindividu": 8, "wonder": 8, "obvious": 8, "wrong": 8, "resembl": 8, "nearli": 8, "complex": 8, "mostli": 8, "ones": 8, "num_popul": 8, "notebook": 8, "schemat": 8, "chosen": 8, "demesdraw": 8, "size_histori": 8, "tube": 8, "visual": 8, "to_dem": 8, "lower": 8, "ingredi": 8, "num_sit": 8, "152582": 8, "152": 8, "582": 8, "variant": 8, "got": 8, "num_sampl": 8, "enumer": 8, "len": 8, "predefin": 8, "mind": 8, "sequence_length": 8, "2820402396300886e": 8, "crazi": 8, "num_mut": 8, "1322": 8, "num_tre": 8, "1mb": 8, "notic": 8, "write_vcf": 8, "vcf_file": 8, "contig_id": 8, "fileformat": 8, "vcfv4": 8, "filter": 8, "gt": 8, "chrom": 8, "po": 8, "alt": 8, "qual": 8, "tsk_0": 8, "tsk_1": 8, "tsk_2": 8, "tsk_3": 8, "tsk_4": 8, "511": 8, "1209": 8, "1308": 8, "2271": 8, "2637": 8, "3615": 8, "4391": 8, "fact": 8, "pyslim": 8, "extract": 8, "exchang": 8, "10e6": 8, "20e6": 8, "isn": 8, "besid": 8, "fairli": 8, "print_histori": 8, "demographydebugg": 8, "growth_rat": 8, "432124": 8, "14474": 8, "initial_s": 8, "92e": 8, "5920": 8, "7310": 8, "longest": 8, "731": 8, "contextlib": 8, "redirect_stdout": 8, "trees_fil": 8, "temporari": 8, "defineconst": 8, "tmp": 8, "tmp4hyf8ugn": 8, "gui": 8, "investig": 8, "rout": 8, "postprocess": 8, "happili": 8, "dump": 8, "foo_recap": 8, "crucial": 8, "simplifi": 8, "whose": 8, "throw": 8, "extran": 8, "extra": 8, "wast": 8, "slowli": 8, "real": 8, "suitabl": 8, "nonsynonym": 8, "selection_coeff_from_mut": 8, "num_neutr": 8, "nonneutr": 8, "167": 8, "10kb": 8, "flank": 8, "middl": 8, "imagin": 8, "concret": 8, "30000": 8, "gene_interv": 8, "20000": 8, "flatten": 8, "append": 8, "coeff": 8, "3000": 8, "aren": 8, "30e6": 8, "exon_interv": 8, "magnitud": 8, "span_normalis": 8, "pi": 8, "3f": 8, "215": 8, "380": 8, "except": 8, "locus_id": 8, "round": 8, "overwritten": 8, "strongli": 8, "imposs": 8, "comparison": 8, "ts_neutral": 8, "lastli": 8, "side": 8, "despit": 8, "applic": 8, "unscal": 8, "matplotlib": 8, "pyplot": 8, "plt": 8, "neutral_pi": 8, "sweep_pi": 8, "axvlin": 8, "color": 8, "black": 8, "linestyl": 8, "dash": 8, "legend": 8, "xlabel": 8, "ylabel": 8, "vertic": 8, "certainli": 8, "dive": 8, "yourself": 8, "borrow": 8, "arguabl": 8, "biolog": 8, "swath": 8, "breakag": 8, "cellular": 8, "machineri": 8, "varieti": 8, "catalogu": 8, "100kb": 8, "vaquita": 8, "1e5": 8, "mayb": 8, "sites_posit": 8, "10000142": 8, "19999926": 8, "preserv": 8, "10mb": 8, "20mb": 8, "misss": 8, "encod": 8, "surpris": 8, "num_root": 8, "root_threshold": 8, "correctli": 8, "america": 8, "number_sampl": 8, "sampling_time_gener": 8, "1523470111585671e": 8, "took": 8, "laptop": 8, "consol": 8, "denot": 8, "d_": 8, "xy": 8, "quantiti": 8, "sample_set": 8, "sample_list": 8, "tolist": 8, "simpler": 8, "div": 8, "00078192": 8, "00080099": 8, "00080262": 8, "00079789": 8, "00056527": 8, "00063978": 8, "00063219": 8, "00057068": 8, "00062214": 8, "00064897": 8, "n_e": 8, "000472": 8, "nicer": 8, "heatmap": 8, "seaborn": 8, "div_matrix": 8, "pop0": 8, "pop1": 8, "vmin": 8, "squar": 8, "fontweight": 8, "bold": 8, "xtick": 8, "asi": 8, "adm": 8, "ytick": 8, "highest": 8, "lowest": 8, "themselv": 8, "overwhelm": 8, "evid": 8, "5000": 8, "4000": 8, "pop2": 8, "summaris": 8, "allele_frequency_spectrum": 8, "pop_sampl": 8, "dtype": 8, "int32": 8, "polymorph": 8, "polaris": 8, "sfs0": 8, "1686": 8, "2496": 8, "1232": 8, "614": 8, "566": 8, "456": 8, "396": 8, "309": 8, "singleton": 8, "sfs1": 8, "3790": 8, "729": 8, "583": 8, "522": 8, "386": 8, "285": 8, "264": 8, "680": 8, "mysteri": 8, "fold": 8, "9050": 8, "bar_width": 8, "r1": 8, "arang": 8, "r2": 8, "bar": 8, "height": 8, "width": 8, "notabl": 8, "absent": 8}, "objects": {"stdpopsim": [[0, 0, 1, "", "Annotation"], [0, 0, 1, "", "Chromosome"], [0, 0, 1, "", "Citation"], [0, 0, 1, "", "Contig"], [0, 0, 1, "", "DFE"], [0, 0, 1, "", "DemographicModel"], [0, 0, 1, "", "Engine"], [0, 0, 1, "", "Genome"], [0, 0, 1, "", "IsolationWithMigration"], [0, 0, 1, "", "MutationType"], [0, 0, 1, "", "PiecewiseConstantSize"], [0, 0, 1, "", "Population"], [0, 0, 1, "", "Species"], [0, 4, 1, "", "get_default_engine"], [0, 4, 1, "", "get_engine"], [0, 4, 1, "", "get_species"], [0, 4, 1, "", "register_engine"], [0, 4, 1, "", "selective_sweep"]], "stdpopsim.Annotation": [[0, 1, 1, "", "download"], [0, 1, 1, "", "get_chromosome_annotations"], [0, 1, 1, "", "is_cached"]], "stdpopsim.Citation": [[0, 1, 1, "", "assert_valid"], [0, 1, 1, "", "because"], [0, 1, 1, "", "fetch_bibtex"], [0, 1, 1, "", "merge"]], "stdpopsim.Contig": [[0, 1, 1, "", "add_dfe"], [0, 1, 1, "", "add_single_site"], [0, 1, 1, "", "clear_dfes"], [0, 1, 1, "", "dfe_breakpoints"], [0, 2, 1, "", "is_neutral"], [0, 1, 1, "", "mutation_types"], [0, 2, 1, "", "origin"], [0, 1, 1, "", "species_contig"]], "stdpopsim.DFE": [[0, 1, 1, "", "register_qc"]], "stdpopsim.DemographicModel": [[0, 1, 1, "", "get_sample_sets"], [0, 1, 1, "", "get_samples"], [0, 1, 1, "", "register_qc"]], "stdpopsim.Engine": [[0, 1, 1, "", "get_version"], [0, 1, 1, "", "simulate"]], "stdpopsim.Genome": [[0, 1, 1, "", "from_data"], [0, 1, 1, "", "get_chromosome"], [0, 2, 1, "", "mean_gene_conversion_fraction"], [0, 2, 1, "", "mean_mutation_rate"], [0, 2, 1, "", "mean_recombination_rate"], [0, 2, 1, "", "range_gene_conversion_lengths"]], "stdpopsim.MutationType": [[0, 2, 1, "", "is_neutral"]], "stdpopsim.Population": [[0, 1, 1, "", "asdict"]], "stdpopsim.Species": [[0, 1, 1, "", "get_annotations"], [0, 1, 1, "", "get_contig"], [0, 1, 1, "", "get_demographic_model"], [0, 1, 1, "", "get_dfe"]], "stdpopsim.engines": [[0, 0, 1, "", "_MsprimeEngine"]], "stdpopsim.engines._MsprimeEngine": [[0, 3, 1, "", "description"], [0, 3, 1, "", "id"], [0, 1, 1, "", "simulate"]], "stdpopsim.slim_engine": [[0, 0, 1, "", "_SLiMEngine"]], "stdpopsim.slim_engine._SLiMEngine": [[0, 3, 1, "", "description"], [0, 3, 1, "", "id"], [0, 1, 1, "", "recap_and_rescale"], [0, 1, 1, "", "simulate"]]}, "objtypes": {"0": "py:class", "1": "py:method", "2": "py:property", "3": "py:attribute", "4": "py:function"}, "objnames": {"0": ["py", "class", "Python class"], "1": ["py", "method", "Python method"], "2": ["py", "property", "Python property"], "3": ["py", "attribute", "Python attribute"], "4": ["py", "function", "Python function"]}, "titleterms": {"api": [0, 1, 8], "quick": [0, 6], "refer": 0, "speci": [0, 4, 8], "definit": 0, "demograph": [0, 1, 4, 8], "model": [0, 1, 4, 8], "gene": [0, 8], "convers": 0, "bacteri": 0, "recombin": [0, 4], "select": [0, 8], "dfe": [0, 1, 4, 8], "sweep": [0, 8], "gener": [0, 1, 8], "simul": [0, 8], "engin": [0, 8], "catalog": 1, "aed": 1, "aegypti": 1, "genom": [1, 8], "ana": 1, "platyrhyncho": 1, "north": 1, "american": 1, "mallard": 1, "black": 1, "duck": 1, "split": 1, "anoli": 1, "carolinensi": 1, "anophel": 1, "gambia": 1, "stairwayplot": 1, "estim": 1, "n": 1, "t": 1, "gabon": 1, "sampl": [1, 8], "mellifera": 1, "arabidopsi": 1, "thaliana": 1, "genet": [1, 3, 4, 8], "map": [1, 3, 4, 8], "salomeaveraged_tair10": 1, "south": 1, "middl": 1, "atla": 1, "piecewis": 1, "constant": 1, "size": 1, "african": 1, "two": 1, "epoch": 1, "three": 1, "annot": [1, 4], "araport_11_exon": 1, "araport_11_cd": 1, "distribut": 1, "fit": 1, "effect": 1, "gamma_h18": 1, "bo": 1, "tauru": 1, "holstein": 1, "friesian": 1, "cattl": 1, "macleod": 1, "et": 1, "al": 1, "2013": 1, "boitard": 1, "2016": 1, "fleckvieh": 1, "jersei": 1, "angu": 1, "caenorhabd": 1, "elegan": 1, "rockmanriail_ce11": 1, "cani": 1, "familiari": 1, "campbell2016_canfam3_1": 1, "chlamydomona": 1, "reinhardtii": 1, "drosophila": [1, 8], "melanogast": [1, 8], "comeroncrossover_dm6": 1, "comeroncrossoverv2_dm6": 1, "popul": 1, "european": 1, "flybase_bdgp6": 1, "32": 1, "51_exon": 1, "51_cd": 1, "gamma_h17": 1, "lognormalpluspositive_r16": 1, "sechellia": 1, "escherichia": 1, "coli": 1, "gasterosteu": 1, "aculeatu": 1, "helianthu": 1, "annuu": 1, "heliconiu": 1, "melpomen": 1, "homo": 1, "sapien": 1, "hapmapii_grch37": 1, "hapmapii_grch38": 1, "decodesexaveraged_grch36": 1, "decodesexaveraged_grch38": 1, "pyrhoacb_grch38": 1, "pyrhoasw_grch38": 1, "pyrhobeb_grch38": 1, "pyrhocdx_grch38": 1, "pyrhoceu_grch38": 1, "pyrhochb_grch38": 1, "pyrhochs_grch38": 1, "pyrhoclm_grch38": 1, "pyrhoesn_grch38": 1, "pyrhofin_grch38": 1, "pyrhogbr_grch38": 1, "pyrhogih_grch38": 1, "pyrhogwd_grch38": 1, "pyrhoibs_grch38": 1, "pyrhoitu_grch38": 1, "pyrhojpt_grch38": 1, "pyrhokhv_grch38": 1, "pyrholwk_grch38": 1, "pyrhomsl_grch38": 1, "pyrhomxl_grch38": 1, "pyrhopel_grch38": 1, "pyrhopjl_grch38": 1, "pyrhopur_grch38": 1, "pyrhostu_grch38": 1, "pyrhotsi_grch38": 1, "pyrhoyri_grch38": 1, "out": 1, "africa": 1, "an": [1, 8], "extend": 1, "puls": 1, "neandert": 1, "admixtur": 1, "archaic": 1, "period": 1, "growth": 1, "declin": 1, "multi": 1, "ancient": 1, "eurasia": 1, "papuan": 1, "ashkenazi": 1, "jewish": 1, "substructur": 1, "4": [1, 8], "europ": 1, "ensembl_havana_104_exon": 1, "ensembl_havana_104_cd": 1, "gamma_k17": 1, "lognormal_h17": 1, "mixed_k23": 1, "mu": 1, "musculu": 1, "m": 1, "domesticu": 1, "oryza": 1, "sativa": 1, "bottleneck": 1, "migrat": 1, "origin": 1, "domest": 1, "rice": 1, "varieti": 1, "pan": 1, "troglodyt": 1, "ghost": 1, "bonobo": 1, "papio": 1, "anubi": 1, "pyrho_panubis1_0": 1, "smc": 1, "individu": 1, "phocoena": 1, "sinu": 1, "vaquita": 1, "phocoena_sinu": 1, "mphosin1": 1, "pri": 1, "110_exon": 1, "110_cd": 1, "gamma_r22": 1, "pongo": 1, "abelii": 1, "naterpa_ponabe3": 1, "naterpp_ponabe3": 1, "orangutan": 1, "streptococcu": 1, "agalactia": 1, "changelog": 2, "0": 2, "2": [2, 8], "1a": 2, "2024": 2, "07": 2, "06": 2, "2022": 2, "11": 2, "01": 2, "1": [2, 8], "2020": 2, "05": 2, "29": 2, "02": 2, "2019": 2, "12": 2, "18": 2, "command": [3, 8], "line": [3, 8], "option": [3, 8], "posit": 3, "argument": 3, "name": [3, 4], "msprime": 3, "specif": 3, "paramet": [3, 4], "slim": [3, 8], "sub": 3, "aedaeg": 3, "anapla": 3, "anocar": 3, "anogam": 3, "apimel": 3, "aratha": 3, "bostau": 3, "caeel": 3, "canfam": 3, "chlrei": 3, "dromel": 3, "drosec": 3, "esccol": 3, "gasacu": 3, "helann": 3, "helmel": 3, "homsap": 3, "musmu": 3, "orysat": 3, "pantro": 3, "papanu": 3, "phosin": 3, "ponab": 3, "straga": 3, "download": 3, "develop": 4, "instal": [4, 6], "us": [4, 8], "virtual": 4, "environ": 4, "github": 4, "workflow": 4, "pre": 4, "commit": 4, "check": [4, 8], "rebas": 4, "when": 4, "goe": 4, "wrong": 4, "ad": 4, "new": 4, "which": 4, "inform": 4, "do": 4, "i": 4, "need": 4, "have": 4, "my": 4, "get": [4, 7], "set": [4, 8], "up": [4, 8], "add": 4, "code": 4, "test": 4, "your": 4, "submit": 4, "pr": 4, "overview": 4, "stdpopsim": [4, 5, 8], "review": 4, "process": 4, "implement": 4, "what": 4, "ar": 4, "appropri": 4, "tabl": [4, 5], "doc": 4, "lift": 4, "over": 4, "standard": 4, "convent": 4, "unit": 4, "coverag": 4, "document": [4, 5], "make": 4, "releas": 4, "welcom": 5, "s": 5, "content": 5, "indic": 5, "requir": 6, "conda": 6, "start": 6, "pip": 6, "run": [6, 8], "cli": [6, 8], "introduct": 7, "first": [7, 8], "step": 7, "involv": 7, "citat": 7, "licenc": 7, "usag": 7, "tutori": 8, "interfac": 8, "A": 8, "choos": 8, "contig": 8, "scheme": 8, "convert": 8, "output": 8, "vcf": 8, "specifi": 8, "scale": 8, "factor": 8, "debug": 8, "from": 8, "python": 8, "publish": 8, "pick": 8, "saniti": 8, "tree": 8, "sequenc": 8, "exampl": 8, "other": 8, "The": 8, "burn": 8, "script": 8, "incorpor": 8, "wide": 8, "singl": 8, "3": 8, "exon": 8, "5": 8, "one": 8, "anoth": 8, "tip": 8, "trick": 8, "gotcha": 8, "miss": 8, "data": 8, "coordin": 8, "analys": 8, "calcul": 8, "diverg": 8, "dataset": 8, "plot": 8, "allel": 8, "frequenc": 8, "spectrum": 8, "af": 8}, "envversion": {"sphinx.domains.c": 2, "sphinx.domains.changeset": 1, "sphinx.domains.citation": 1, "sphinx.domains.cpp": 6, "sphinx.domains.index": 1, "sphinx.domains.javascript": 2, "sphinx.domains.math": 2, "sphinx.domains.python": 3, "sphinx.domains.rst": 2, "sphinx.domains.std": 2, "sphinx.ext.intersphinx": 1, "sphinx.ext.todo": 2, "sphinx.ext.viewcode": 1, "sphinx": 56}})
\ No newline at end of file
+Search.setIndex({"docnames": ["api", "catalog", "changelogs", "cli_arguments", "development", "index", "installation", "introduction", "tutorial"], "filenames": ["api.rst", "catalog.rst", "changelogs.rst", "cli_arguments.rst", "development.rst", "index.rst", "installation.rst", "introduction.rst", "tutorial.rst"], "titles": ["API", "Catalog", "Changelogs", "Command-line options", "Development", "Welcome to stdpopsim\u2019s documentation!", "Installation", "Introduction", "Tutorials"], "terms": {"function": [0, 1, 4, 6, 8], "get": [0, 1, 2, 5, 6, 8], "thing": [0, 4, 8], "class": [0, 2], "object": [0, 1, 4, 8], "The": [0, 1, 2, 3, 4, 6, 7], "catalog": [0, 2, 3, 4, 5, 7, 8], "contain": [0, 1, 4, 6, 8], "larg": [0, 4, 8], "number": [0, 1, 3, 4, 7, 8], "which": [0, 1, 2, 3, 6, 8], "ar": [0, 1, 2, 3, 6, 7, 8], "built": [0, 4, 6, 8], "us": [0, 1, 2, 3, 6, 7], "defin": [0, 1, 2, 4, 8], "here": [0, 1, 2, 4, 6, 7, 8], "These": [0, 1, 3, 4, 8], "usual": [0, 4, 6, 8], "intend": 0, "instanti": 0, "directli": [0, 1, 4, 8], "should": [0, 1, 3, 4, 6, 8], "access": [0, 1, 4, 8], "through": [0, 4, 6, 7, 8], "main": [0, 1, 4, 8], "entri": [0, 8], "point": [0, 1, 2, 4], "get_speci": [0, 4, 8], "stdpopsim": [0, 1, 2, 3, 6, 7], "id": [0, 1, 2, 3, 4, 8], "sourc": [0, 1, 4, 7, 8], "return": [0, 4, 8], "specifi": [0, 2, 3, 4], "paramet": [0, 1, 2, 5, 8], "str": [0, 4], "string": [0, 4, 8], "identifi": [0, 1, 4], "request": [0, 2, 4, 7, 8], "e": [0, 1, 2, 3, 4, 7, 8], "g": [0, 1, 2, 3, 4, 7, 8], "homsap": [0, 1, 2, 4, 8], "A": [0, 1, 3, 4, 7], "complet": [0, 4, 6, 8], "list": [0, 1, 2, 3, 4, 7, 8], "can": [0, 1, 2, 3, 4, 6, 7, 8], "found": [0, 1, 4, 8], "an": [0, 2, 3, 4, 7], "type": [0, 1, 2, 4, 8], "repres": [0, 1, 4, 8], "variabl": [0, 3, 6], "uniqu": [0, 4, 8], "thi": [0, 1, 2, 3, 4, 6, 7, 8], "three": [0, 2, 4, 8], "first": [0, 1, 4, 5], "letter": [0, 4], "genu": 0, "name": [0, 1, 2, 5, 8], "follow": [0, 1, 4, 6, 8], "doe": [0, 1, 4, 8], "ani": [0, 1, 2, 3, 4, 8], "space": [0, 3, 4, 8], "punctuat": 0, "scheme": [0, 1, 2, 4], "similar": [0, 2, 4, 8], "approach": 0, "ucsc": [0, 4], "genom": [0, 2, 3, 4, 7], "browser": [0, 4], "homo": [0, 3, 4, 5, 8], "sapien": [0, 3, 4, 5, 8], "full": [0, 3, 4, 6], "binomin": 0, "nomenclatur": 0, "would": [0, 2, 4, 7, 8], "written": [0, 3, 4, 8], "text": [0, 1, 4, 8], "common_nam": [0, 4], "most": [0, 1, 2, 4, 6, 7, 8], "often": [0, 4, 8], "inform": [0, 1, 2, 3, 8], "human": [0, 1, 4, 8], "orang": [0, 1], "utan": [0, 1], "where": [0, 1, 2, 3, 4, 6, 8], "common": [0, 1, 4, 8], "exist": [0, 1, 4, 8], "abbrevi": [0, 4], "coli": [0, 3, 5, 8], "instanc": [0, 1, 3, 4, 8], "describ": [0, 1, 4, 7, 8], "detail": [0, 1, 2, 3, 4, 6, 7, 8], "generation_tim": [0, 2, 4], "float": 0, "current": [0, 1, 4, 7, 8], "best": [0, 1, 4, 7], "estim": [0, 2, 4, 8], "time": [0, 1, 2, 3, 4, 8], "year": [0, 1, 4, 7], "note": [0, 1, 3, 4, 8], "individu": [0, 2, 3, 4, 7, 8], "mai": [0, 3, 4, 6, 7, 8], "each": [0, 1, 2, 3, 4, 8], "wa": [0, 1, 2, 4, 6, 8], "origin": [0, 2, 4, 7, 8], "public": [0, 1, 2, 4, 7], "s": [0, 1, 2, 3, 4, 7, 8], "ploidi": [0, 1, 2, 4, 8], "int": [0, 4, 8], "organ": [0, 1, 7], "population_s": [0, 4, 8], "popul": [0, 2, 3, 4, 7, 8], "size": [0, 2, 3, 4, 8], "citat": [0, 1, 2, 3, 4, 5, 8], "provid": [0, 1, 2, 3, 4, 7, 8], "demographic_model": [0, 4, 8], "demographicmodel": [0, 1, 4], "ensembl_id": [0, 4], "ensembl": [0, 1, 2, 4, 8], "mainten": [0, 1, 2, 4], "script": [0, 1, 3, 4], "queri": 0, "databas": [0, 1], "get_annot": [0, 8], "set": [0, 1, 2, 3, 6], "annot": [0, 2, 3, 5, 8], "subsect": 0, "hold": 0, "from": [0, 1, 2, 3, 4, 7], "get_contig": [0, 8], "chromosom": [0, 1, 2, 3, 4, 8], "none": [0, 1, 3, 4], "genetic_map": [0, 3, 4, 8], "length_multipli": [0, 3, 8], "1": [0, 1, 3, 4, 5], "length": [0, 1, 2, 3, 4, 8], "mutation_r": [0, 4, 8], "recombination_r": [0, 4], "use_species_gene_convers": 0, "fals": [0, 2, 3, 8], "inclusion_mask": [0, 3, 8], "exclusion_mask": [0, 3, 8], "left": [0, 2, 3, 8], "right": [0, 2, 3, 4, 6, 8], "contig": [0, 2, 3, 4], "section": [0, 4, 8], "base": [0, 1, 4, 8], "empir": [0, 8], "given": [0, 1, 3, 4, 8], "coordin": [0, 2, 3], "If": [0, 3, 4, 7, 8], "particular": [0, 3, 6, 7, 8], "chunk": [0, 8], "obtain": [0, 1, 4, 6, 8], "result": [0, 2, 4, 8], "have": [0, 1, 2, 3, 8], "match": [0, 2, 4, 8], "portion": [0, 8], "outsid": [0, 2, 3, 8], "mask": [0, 2, 3], "so": [0, 1, 2, 3, 4, 7, 8], "miss": [0, 2, 4], "data": [0, 1, 2, 4], "shift": [0, 2], "rel": [0, 2, 8], "desir": [0, 8], "output": [0, 1, 2, 3, 4], "tskit": [0, 3, 4, 8], "treesequ": [0, 2, 8], "trim": [0, 2], "method": [0, 1, 2, 4, 6, 8], "ts_shift": 0, "ts": [0, 2, 8], "we": [0, 1, 2, 3, 4, 6, 7, 8], "rate": [0, 1, 2, 3, 4, 8], "genet": [0, 2, 5, 7], "map": [0, 2, 5], "default": [0, 2, 3, 4, 6, 8], "uniform": [0, 2, 3, 4, 8], "region": [0, 1, 2, 4, 8], "specif": [0, 1, 2, 4, 5, 6, 8], "same": [0, 1, 3, 4, 6, 8], "mutat": [0, 1, 2, 3, 4, 8], "option": [0, 1, 2, 4, 5, 6], "cannot": [0, 4, 8], "conjunct": 0, "argument": [0, 2, 4, 5, 8], "per": [0, 1, 2, 4, 7, 8], "ignor": [0, 4], "when": [0, 1, 6, 8], "bool": 0, "true": [0, 2, 8], "avail": [0, 1, 3, 4, 6, 7, 8], "For": [0, 1, 3, 4, 7, 8], "fraction": [0, 1, 8], "mean": [0, 1, 2, 4, 6, 8], "valu": [0, 1, 2, 3, 4, 8], "across": [0, 1, 3, 4, 8], "all": [0, 1, 2, 3, 4, 7, 8], "subset": [0, 1, 8], "onli": [0, 1, 4, 8], "inlud": 0, "path": [0, 3, 6, 8], "file": [0, 1, 2, 3, 4, 8], "bed": [0, 2, 3, 8], "arrai": [0, 1, 8], "interv": [0, 1, 2, 3, 8], "end": [0, 1, 3, 4, 8], "exclud": 0, "sequenc": [0, 1, 2, 3, 4, 7], "equal": [0, 1, 4], "wide": [0, 1, 4], "averag": [0, 1, 4, 8], "autosom": [0, 1, 2, 8], "inclus": [0, 2, 3, 4, 7], "keep": [0, 2, 3, 8], "0": [0, 1, 3, 4, 5, 8], "remain": [0, 4], "exclus": [0, 2, 3], "get_demographic_model": [0, 4, 8], "get_df": [0, 8], "todo": 0, "add": [0, 2, 6, 8], "assembly_nam": 0, "assembl": [0, 1, 2, 4], "assembly_access": 0, "bacterial_recombin": 0, "whether": [0, 3, 4, 8], "via": [0, 1, 2, 4, 8], "horizont": 0, "transfer": 0, "cross": [0, 1, 4, 8], "over": [0, 1, 2, 3, 5, 8], "possibl": [0, 1, 2, 3, 4, 6, 7, 8], "total": [0, 1, 4, 8], "static": 0, "from_data": [0, 4], "genome_data": [0, 4], "gene_conversion_fract": 0, "gene_conversion_length": 0, "construct": [0, 1], "dictionari": [0, 4], "intern": [0, 1, 4, 8], "get_chromosom": [0, 4], "properti": [0, 4], "mean_gene_conversion_fract": 0, "weight": [0, 4], "mean_mutation_r": 0, "mean_recombination_r": 0, "doubl": [0, 1, 4], "strand": 0, "break": [0, 2, 8], "range_gene_conversion_length": 0, "rang": [0, 1, 4, 8], "tract": [0, 1, 3], "singl": [0, 1, 2, 3, 4], "although": [0, 6, 8], "give": [0, 1, 4, 8], "both": [0, 1, 3, 4, 8], "differ": [0, 1, 2, 4, 6, 8], "nonzero": 0, "event": [0, 1, 2, 4, 8], "synonym": [0, 1, 4, 8], "command": [0, 1, 2, 4, 5, 6], "line": [0, 1, 2, 4, 5, 6], "interfac": [0, 1, 3, 4, 5, 6], "contigu": 0, "about": [0, 1, 4, 8], "distribut": [0, 2, 3, 4, 8], "fit": [0, 2, 3, 4, 8], "effect": [0, 2, 3, 4, 8], "need": [0, 1, 3, 6, 8], "target": 0, "dfe_list": 0, "interval_list": 0, "must": [0, 1, 3, 4, 8], "k": [0, 7, 8], "th": 0, "appli": [0, 4, 8], "see": [0, 1, 2, 3, 4, 6, 7, 8], "add_df": [0, 4, 8], "more": [0, 1, 2, 4, 6, 8], "2": [0, 1, 3, 4, 5], "diploid": [0, 1, 3, 8], "geneticmap": [0, 1, 2, 4], "recombination_map": [0, 8], "msprime": [0, 2, 4, 5, 6, 7, 8], "ratemap": 0, "larger": [0, 8], "than": [0, 1, 2, 3, 4, 6, 8], "correspond": [0, 1, 4, 8], "sinc": [0, 1, 4, 8], "i": [0, 1, 3, 8], "resolv": [0, 2, 4], "between": [0, 1, 2, 4, 8], "tranfer": 0, "segment": [0, 2, 8], "present": [0, 1, 4, 8], "abov": [0, 1, 4, 6, 8], "either": [0, 3, 4, 6, 8], "mask_interv": 0, "like": [0, 1, 4, 6, 7, 8], "tree": [0, 1, 2, 3, 7], "left_posit": 0, "right_posit": 0, "non": [0, 1, 2, 3, 4, 8], "overlap": [0, 1, 3], "ascend": 0, "order": [0, 4, 8], "shape": [0, 1, 4], "nx2": 0, "n": [0, 3, 7, 8], "By": [0, 3, 8], "neutral": [0, 1, 3, 4, 8], "np": [0, 8], "integ": [0, 2, 8], "init": 0, "span": [0, 8], "whole": [0, 1, 8], "tupl": [0, 8], "locat": [0, 1, 8], "form": [0, 1, 2, 4], "assum": [0, 1, 4, 8], "inherit": [0, 1], "system": [0, 4, 6, 8], "To": [0, 1, 2, 4, 8], "run": [0, 1, 2, 3, 4, 5, 7], "altern": [0, 4], "user": [0, 2, 4, 6, 8], "new": [0, 1, 2, 5, 8], "creat": [0, 4, 7, 8], "one": [0, 1, 2, 3, 4, 6], "new_contig": 0, "old_contig": 0, "also": [0, 1, 2, 3, 4, 6, 8], "remov": [0, 1, 2, 4, 8], "previous": [0, 1, 2], "other": [0, 1, 2, 4, 7], "word": [0, 8], "recent": [0, 1, 4, 6], "ad": [0, 1, 2, 5, 8], "take": [0, 2, 3, 4, 8], "preced": [0, 3, 8], "wai": [0, 4, 6, 8], "carri": [0, 8], "its": [0, 4, 6], "own": [0, 4], "mutationtyp": [0, 2, 4, 8], "share": [0, 4, 8], "call": [0, 1, 2, 4, 8], "even": [0, 4, 8], "onc": [0, 4, 6, 8], "do": [0, 1, 3, 6, 8], "a1": [0, 4], "100": [0, 1, 4, 8], "a2": [0, 4], "50": [0, 1, 8], "120": [0, 1], "dfe1": 0, "dfe2": 0, "fall": [0, 8], "clip": [0, 8], "boundari": [0, 8], "empti": [0, 4], "warn": [0, 2], "valid": [0, 1, 4], "add_single_sit": [0, 8], "descript": [0, 1, 3, 4, 8], "long_descript": [0, 4, 8], "site": [0, 1, 8], "label": [0, 1, 4, 8], "referenc": 0, "extend": [0, 2, 8], "pass": [0, 2, 4, 8], "pop_0": [0, 8], "start": [0, 1, 3, 4, 8], "1000": [0, 1, 3, 4, 8], "past": [0, 1, 4], "hard_sweep": 0, "mutation_coordin": 0, "extended_ev": [0, 8], "ext": [0, 2], "selective_sweep": [0, 8], "mutation_generation_ago": [0, 8], "selection_coeff": [0, 8], "get_engin": [0, 8], "slim": [0, 1, 2, 4, 5, 7], "ts_sweep": [0, 8], "short": [0, 4], "strong": 0, "necessari": [0, 2, 4, 6, 8], "summari": [0, 1, 8], "clear_df": 0, "well": [0, 1, 2, 4, 7, 8], "dfe_breakpoint": [0, 2, 8], "relative_coordin": [0, 2], "two": [0, 2, 3, 4, 6, 8], "sort": 0, "vector": 0, "endpoint": [0, 8], "sai": [0, 3, 4, 8], "goe": 0, "complementari": 0, "tell": [0, 8], "bit": [0, 4, 8], "ha": [0, 1, 2, 3, 4, 6, 8], "attach": [0, 8], "conveni": [0, 6], "column": [0, 4], "suppos": [0, 1, 4, 8], "cover": [0, 4, 8], "dfe_label": 0, "those": [0, 1, 2, 3, 4, 6, 8], "increas": [0, 1, 3, 8], "index": [0, 1, 2, 4, 5, 8], "alwai": 0, "j": [0, 1, 4, 7, 8], "some": [0, 1, 2, 4, 6, 7, 8], "case": [0, 2, 4, 6, 8], "thei": [0, 1, 2, 3, 4, 8], "bewar": [0, 4], "python": [0, 1, 4, 5, 6], "is_neutr": 0, "mutation_typ": [0, 4], "assign": [0, 4], "along": [0, 4, 8], "becaus": [0, 1, 4, 8], "numer": [0, 2, 3], "encount": [0, 4, 6], "iter": 0, "easi": [0, 1, 4, 8], "back": [0, 4, 8], "dfe_id": 0, "come": [0, 1, 8], "mut": [0, 8], "code": [0, 1, 2, 3, 5, 7, 8], "print": [0, 3, 4, 8], "mut_typ": 0, "m": [0, 4, 6, 7], "md": 0, "metadata": [0, 2, 8], "muation_list": 0, "f": [0, 4, 7, 8], "join": [0, 4, 7], "format": [0, 1, 3, 4, 7, 8], "species_contig": 0, "build": [0, 4, 7, 8], "literatur": [0, 3, 4, 8], "acknowledg": 0, "doi": [0, 1, 4, 7, 8], "author": [0, 1, 4, 7], "et": [0, 2, 4, 8], "al": [0, 2, 4, 8], "4": [0, 2, 3, 4, 7], "digit": [0, 4, 8], "2008": [0, 1, 8], "assert_valid": 0, "check": [0, 1], "reason": [0, 4, 8], "fetch_bibtex": 0, "retriev": [0, 1], "bibtex": [0, 3, 7], "crossref": 0, "merg": [0, 4], "dedupl": 0, "track": [0, 1, 2, 3, 4, 8], "url": [0, 4, 7], "pack": 0, "compress": [0, 4], "gff3": 0, "intervals_url": 0, "cach": [0, 3, 4], "intervals_sha256": 0, "sha256": [0, 4], "checksum": [0, 4], "One": [0, 4, 8], "file_pattern": [0, 4], "pattern": [0, 4], "download": [0, 1, 4, 8], "store": [0, 2, 3, 4, 8], "directori": [0, 3, 4, 6], "get_chromosome_annot": [0, 8], "numpi": [0, 8], "is_cach": 0, "local": [0, 4, 6], "implementor": 0, "develop": [0, 1, 5, 7], "document": [0, 2, 3, 6, 7, 8], "instead": [0, 2, 4, 8], "pre": [0, 6], "memor": 0, "conform": [0, 4], "convent": [0, 5], "out": [0, 2, 4, 6, 7, 8], "africa": [0, 2, 4, 8], "itself": [0, 8], "concis": [0, 8], "inter": 0, "primari": [0, 4, 7], "associ": [0, 2, 4, 8], "get_sample_set": 0, "individuals_per_popul": 0, "sampleset": 0, "sampl": [0, 2, 3, 4, 7], "5": [0, 1, 2, 3, 4, 6], "pop_1": 0, "encompass": 0, "10": [0, 1, 2, 3, 4, 7, 8], "split": [0, 4, 8], "omit": [0, 3, 8], "zero": [0, 3, 8], "dict": 0, "population_nam": [0, 8], "number_of_sampl": [0, 8], "count": [0, 4, 8], "get_sampl": 0, "arg": 0, "haploid": [0, 2, 8], "determin": [0, 4, 8], "posit": [0, 2, 4, 5, 8], "7": [0, 1, 3, 4, 8], "14": [0, 1, 3, 8], "five": [0, 4, 8], "second": [0, 1, 4, 8], "seven": [0, 4], "third": [0, 1, 8], "less": [0, 1, 4, 8], "num_sampling_popul": [0, 8], "treat": [0, 1], "register_qc": [0, 4], "qc_model": 0, "regist": [0, 4], "qc": [0, 2, 4], "implement": [0, 1, 8], "record": [0, 2, 4, 7, 8], "sampling_tim": 0, "indic": [0, 4, 8], "how": [0, 1, 4, 6, 7, 8], "mani": [0, 2, 4, 8], "prior": 0, "drawn": [0, 4, 8], "allow": [0, 2, 4, 8], "asdict": 0, "process": [0, 1, 8], "howev": [0, 4, 6, 8], "happen": [0, 4, 8], "unfortun": 0, "make": [0, 1, 5, 6, 7, 8], "much": [0, 4, 8], "longer": [0, 2, 4, 8], "bigger": 0, "higher": [0, 8], "enabl": [0, 4], "runtim": 0, "attribut": [0, 2, 4], "visibl": 0, "r": [0, 1, 4, 7, 8], "consequ": [0, 8], "initi": [0, 1, 2, 4, 8], "terminolog": 0, "conflict": [0, 4], "somewhat": [0, 8], "otherwis": [0, 3, 4, 8], "includ": [0, 1, 4, 8], "dromel": [0, 1, 2, 4, 8], "2l": [0, 1, 3, 4, 8], "mean_rat": [0, 8], "40462600791e": 0, "08": [0, 1, 3, 8], "414485887005882e": 0, "07": [0, 1, 3, 5, 8], "write": [0, 2, 3, 4], "constant": [0, 3, 8], "while": [0, 1, 4, 8], "fix": [0, 1, 2, 4, 8], "In": [0, 1, 4, 6, 8], "principl": [0, 8], "issu": [0, 1, 2, 4, 7], "mechan": 0, "flag": [0, 2, 8], "It": [0, 1, 4, 6, 8], "could": [0, 4, 8], "homolog": 0, "anoth": [0, 4], "kind": 0, "collect": [0, 4], "overal": 0, "proport": [0, 1, 4, 8], "entir": [0, 3, 4, 8], "occur": [0, 1, 4, 8], "nonneg": 0, "sum": [0, 4, 8], "lognorm": [0, 1, 4], "qc_dfe": 0, "design": [0, 4, 7, 8], "close": [0, 4, 8], "mirror": 0, "draw": [0, 3, 8], "coeffici": [0, 2, 4, 8], "distribution_typ": [0, 4], "manual": [0, 1, 3, 4, 8], "exponenti": [0, 1, 2], "gamma": [0, 1, 4, 8], "normal": [0, 1], "sd": 0, "w": [0, 7, 8], "weibul": 0, "scale": [0, 3, 4], "u": 0, "min": 0, "max": [0, 4, 8], "lp": 0, "log": [0, 1, 3, 4], "rlnorm": 0, "ln": 0, "neg": [0, 1, 4, 8], "multipli": [0, 3], "domin": [0, 1, 2, 4], "dominance_coeff": [0, 4], "discret": [0, 2], "relationship": [0, 2, 8], "dominance_coeff_list": [0, 2], "dominance_coeff_break": 0, "below": [0, 4, 8], "forth": [0, 4, 8], "therefor": [0, 8], "distribution_arg": [0, 4], "underdomin": 0, "recess": 0, "addit": [0, 1, 2, 4, 7, 8], "overdomin": 0, "convert_to_substitut": 0, "retain": [0, 2, 8], "ask": [0, 4, 8], "frequenc": [0, 1, 2], "shorter": [0, 4, 8], "test": [0, 1, 5, 7, 8], "strictli": 0, "situat": [0, 8], "produc": [0, 1, 2, 4, 8], "extendedev": 0, "subclass": 0, "condit": [0, 2, 8], "loci": 0, "chang": [0, 1, 2, 3, 4, 8], "futur": [0, 4], "stabl": [0, 3, 4], "single_site_id": [0, 8], "start_generation_ago": 0, "end_generation_ago": 0, "min_freq_at_start": 0, "min_freq_at_end": [0, 8], "globally_adapt": 0, "subsequ": [0, 1], "introduc": [0, 8], "becom": [0, 4], "benefici": [0, 1, 4, 8], "global": [0, 7], "control": [0, 2], "restart": 0, "after": [0, 1, 4, 6, 8], "revert": 0, "dure": [0, 1, 4, 6, 8], "homozyg": [0, 1], "heterozyg": 0, "respect": [0, 1, 4, 8], "impact": [0, 8], "regardless": [0, 3, 4, 7, 8], "belong": [0, 3], "influenc": [0, 8], "within": [0, 1, 4, 8], "lost": [0, 4], "aka": 0, "reject": [0, 4], "being": [0, 4, 8], "extant": 0, "until": [0, 4, 8], "allel": [0, 1, 2, 3], "satisfi": [0, 4], "care": [0, 4, 8], "taken": [0, 1, 4, 8], "ensur": [0, 4], "exampl": [0, 4, 5, 7], "veri": [0, 4, 8], "substanti": [0, 1, 8], "greater": [0, 8], "vast": 0, "major": [0, 2, 7], "propos": [0, 8], "trajectori": 0, "infeas": 0, "long": [0, 1, 2, 4, 8], "switch": [0, 2, 8], "hard": [0, 4, 8], "minimum": [0, 4], "abl": [0, 4, 8], "pleas": [0, 1, 3, 4, 6, 7], "piecewiseconstants": [0, 1, 8], "n0": 0, "piecewis": [0, 8], "instantan": [0, 1, 8], "multipl": [0, 1, 3, 4], "epoch": [0, 8], "t": [0, 3, 4, 8], "place": [0, 4], "usag": [0, 3, 5, 8], "illustr": [0, 8], "model1": 0, "t1": 0, "n1": [0, 1, 8], "model2": 0, "t2": 0, "n2": [0, 8], "isolationwithmigr": [0, 1, 8], "na": [0, 8], "m12": [0, 8], "m21": [0, 8], "isol": [0, 1, 8], "migrat": [0, 2, 4, 8], "ancestr": [0, 1, 2, 4, 8], "ago": [0, 1, 8], "disallow": 0, "support": [0, 2, 4, 7, 8], "abstract": 0, "register_engin": 0, "get_default_engin": 0, "At": [0, 3, 4, 8], "get_vers": 0, "py": [0, 1, 4], "version": [0, 1, 3, 4, 6], "seed": [0, 3, 8], "dry_run": 0, "random": [0, 3, 8], "without": [0, 1, 3, 4, 6, 8], "succinct": 0, "_msprimeengin": 0, "coalesc": [0, 1, 8], "msprime_model": 0, "msprime_change_model": 0, "kwarg": 0, "hudson": [0, 3, 8], "dtwf": [0, 2, 3, 8], "smc": [0, 2, 3, 8], "smc_prime": [0, 3, 8], "end_tim": 0, "initialis": 0, "immedi": 0, "further": [0, 1, 4, 7, 8], "sim_ancestri": 0, "slim_engin": 0, "_slimengin": 0, "forward": [0, 4, 8], "wright": 0, "fisher": 0, "recap_and_rescal": [0, 8], "slim_scaling_factor": [0, 8], "keep_mutation_ids_as_allel": 0, "post": [0, 1], "transform": 0, "rescal": [0, 3, 8], "node": [0, 8], "recapit": [0, 8], "simplif": [0, 1, 8], "procedur": [0, 4, 8], "been": [0, 1, 2, 4, 7, 8], "had": [0, 1, 8], "were": [0, 1, 2, 4, 8], "hope": 0, "But": [0, 8], "anticip": 0, "what": [0, 2, 6, 7, 8], "you": [0, 1, 3, 4, 6, 7, 8], "ll": [0, 1, 4, 8], "befor": [0, 1, 4, 8], "consult": 0, "behaviour": [0, 8], "appropri": 0, "your": [0, 1, 6, 7, 8], "slim_path": [0, 8], "slim_script": [0, 8], "slim_burn_in": [0, 8], "verbos": [0, 2, 3, 8], "logfil": 0, "logfile_interv": 0, "_recap_and_rescal": 0, "execut": [0, 3, 4, 6], "stdout": [0, 3, 8], "speed": [0, 3, 8], "up": [0, 3, 6], "divid": [0, 8], "factor": [0, 2, 3], "wherea": [0, 2], "growth": [0, 2, 8], "improv": [0, 2, 3, 4, 6, 7], "perform": [0, 1, 2, 3, 4, 8], "burn": [0, 3], "phase": [0, 1, 3, 4, 8], "unit": [0, 1, 2, 3, 5, 8], "setup": [0, 4], "statist": [0, 1, 2, 4, 8], "rather": [0, 3, 4, 6, 8], "randomli": [0, 1, 8], "nucleotid": [0, 2, 3, 8], "With": 1, "simul": [1, 2, 3, 4, 5, 6, 7], "publish": [1, 4, 7], "histori": [1, 4, 7, 8], "rigor": 1, "peopl": 1, "rest": [1, 4, 8], "know": [1, 4, 8], "reproduc": [1, 6, 7, 8], "bug": [1, 2, 7], "free": [1, 4, 7], "show": [1, 3, 4, 8], "configur": [1, 4], "organis": 1, "around": [1, 4, 8], "choic": [1, 3, 8], "speci": [1, 2, 3, 5, 7], "wish": [1, 4, 8], "recombin": [1, 2, 3, 5, 8], "interest": [1, 4, 7, 8], "modern": [1, 8], "22": [1, 3, 4, 8], "hapmapii": 1, "under": [1, 2, 4, 7, 8], "3": [1, 2, 3, 4, 6], "background": [1, 2, 7], "select": [1, 2, 3, 4, 5], "act": [1, 3], "exon": [1, 2], "havana": [1, 8], "104": 1, "yri": [1, 2, 4, 8], "ceu": [1, 2, 8], "chb": [1, 2, 8], "save": [1, 4, 8], "c": [1, 3, 4, 6, 7, 8], "chr22": [1, 3, 8], "o": [1, 3, 4, 8], "d": [1, 2, 3, 4, 7, 8], "outofafrica_3g09": [1, 2, 3, 4, 8], "learn": [1, 4, 7], "read": [1, 4, 7, 8], "our": [1, 4, 7, 8], "tutori": [1, 4, 5, 6, 7], "known": [1, 3, 4], "head": [1, 4, 7], "page": [1, 4, 5, 7], "item": [1, 4], "Then": [1, 4], "feel": [1, 4], "readi": [1, 4, 8], "github": [1, 2, 3, 5, 7], "aedaeg": [1, 8], "yellow": [1, 4], "fever": 1, "mosquito": 1, "06666666666666667": [1, 3], "crawford": 1, "2017": [1, 4, 8], "1000000": [1, 3, 4, 8], "310827022": 1, "06e": 1, "09": [1, 3], "5e": [1, 3], "474425716": 1, "49e": [1, 3], "409777670": 1, "91e": 1, "mt": [1, 3, 4], "16790": 1, "bp": [1, 4], "anapla": [1, 2, 8], "lavretski": 1, "2020": [1, 5, 7], "156000": [1, 3], "guo": 1, "2021": 1, "208326429": 1, "52e": 1, "83e": [1, 3], "162939446": 1, "39e": 1, "119723720": 1, "9": [1, 3, 4, 7, 8], "38e": 1, "77626585": 1, "2e": [1, 3], "64988622": 1, "21e": 1, "6": [1, 2, 3, 4, 8], "39543408": 1, "04e": 1, "37812880": 1, "59e": 1, "8": [1, 3, 4, 8], "33348632": 1, "28e": 1, "26742597": 1, "34e": 1, "22933227": 1, "11": [1, 3, 5, 8], "22193879": 1, "12": [1, 3, 5, 7, 8], "22338721": 1, "15e": 1, "13": [1, 3, 8], "21714986": 1, "41e": 1, "20320564": 1, "61e": 1, "15": [1, 3, 8], "18227546": 1, "79e": 1, "16": [1, 3, 8], "16053328": 1, "86e": 1, "17": [1, 3, 4, 8], "15319648": 1, "13e": 1, "18": [1, 3, 5, 8], "13333155": 1, "58e": 1, "19": [1, 2, 3, 8], "12198306": 1, "43e": 1, "20": [1, 3, 4, 8], "12091001": 1, "21": [1, 3], "8553409": 1, "16160689": 1, "23": [1, 3, 7], "7977799": 1, "24": [1, 3], "7737077": 1, "25": [1, 3], "7574731": 1, "26": [1, 3], "6918023": 1, "27": [1, 3, 4], "6270716": 1, "28": [1, 3], "5960150": 1, "29": [1, 3, 5], "1456683": 1, "30": [1, 3, 8], "1872559": 1, "z": [1, 3], "81233375": 1, "31": [1, 3, 8], "2637124": 1, "3473573": 1, "33": [1, 3, 4, 8], "2151773": 1, "34": [1, 3], "7214884": 1, "35": [1, 3], "5548691": 1, "36": [1, 3, 8], "3997205": 1, "37": [1, 3, 8], "3148754": 1, "38": [1, 3], "2836164": 1, "39": [1, 3, 4], "2018729": 1, "40": [1, 3], "1354177": 1, "mallardblackduck_2l19": [1, 2, 3], "contemporari": [1, 8], "wild": 1, "dadi": 1, "figur": [1, 4, 8], "2019": [1, 4, 5], "num": 1, "black_duck": 1, "158076": 1, "http": [1, 3, 4, 7, 8], "org": [1, 4, 7, 8], "1111": 1, "mec": 1, "15343": 1, "819": 1, "535": 1, "pop": [1, 8], "570": 1, "000": [1, 8], "370": 1, "x10": 1, "gen": 1, "72": 1, "yr": 1, "subst": 1, "anocar": [1, 8], "anol": 1, "lizard": 1, "lovern": 1, "2004": [1, 4], "3050000": [1, 3], "pombi": 1, "263920458": 1, "1e": [1, 3], "199619895": 1, "204416410": 1, "156502444": 1, "150641573": 1, "80741955": 1, "lga": [1, 3], "7025928": 1, "lgb": [1, 3], "3271537": 1, "lgc": [1, 3], "9478905": 1, "lgd": [1, 3], "1094478": 1, "lgf": [1, 3], "4257874": 1, "lgg": [1, 3], "424765": 1, "lgh": [1, 3], "248369": 1, "17223": 1, "anogam": [1, 2, 8], "09090909090909091": [1, 3], "ag1000g": 1, "consortium": [1, 3, 4, 7], "49364325": 1, "3e": [1, 8], "2r": [1, 3], "61545105": 1, "3l": [1, 3], "41963435": 1, "3r": [1, 3], "53200684": 1, "6e": [1, 3], "x": [1, 3, 4, 8], "24393108": 1, "15363": 1, "gabonag1000g_1a17": [1, 2, 3], "done": [1, 4, 6, 8], "part": [1, 4, 8], "paper": [1, 4, 7, 8], "misorient": 1, "sf": [1, 8], "110": [1, 8], "distinct": [1, 4, 8], "report": [1, 4, 8], "tabl": 1, "ga": 1, "1038": 1, "nature24995": 1, "069": 1, "863": [1, 2], "205": [1, 8], "766": 1, "apimel": [1, 8], "dh4": 1, "nelson": 1, "200000": [1, 3], "wallberg": 1, "2014": [1, 2, 4, 8], "cm009931": [1, 3], "27754200": 1, "4e": [1, 3, 8], "cm009932": [1, 3], "16089512": 1, "46e": 1, "cm009933": [1, 3], "13619445": 1, "cm009934": [1, 3], "13404451": 1, "76e": 1, "cm009935": [1, 3], "13896941": 1, "14e": 1, "cm009936": [1, 3], "17789102": 1, "12e": 1, "cm009937": [1, 3], "14198698": 1, "cm009938": [1, 3], "12717210": 1, "09e": 1, "cm009939": [1, 3], "12354651": 1, "cm009940": [1, 3], "12360052": 1, "48e": 1, "cm009941": [1, 3], "16352600": 1, "03e": 1, "cm009942": [1, 3], "11514234": 1, "cm009943": [1, 3], "11279722": 1, "cm009944": [1, 3], "10670842": 1, "cm009945": [1, 3], "9534514": 1, "cm009946": [1, 3], "7238532": 1, "cm009947": [1, 3], "16343": 1, "aratha": [1, 2, 4, 8], "donohu": [1, 4], "2002": [1, 4], "10000": [1, 3, 8], "1001genomesconsortium": [1, 4], "30427671": 1, "06452e": 1, "7e": [1, 3, 4], "19698289": 1, "23459830": 1, "18585056": 1, "26975502": 1, "366924": 1, "pt": [1, 3, 4], "154478": 1, "2012": [1, 8], "crossov": 1, "studi": [1, 4, 8], "7000": 1, "plant": 1, "f2": 1, "deriv": [1, 4, 8], "salom\u00e9": 1, "haldan": 1, "distanc": 1, "convert": [1, 2, 4], "cm": [1, 4], "mb": [1, 4, 8], "loess": 1, "tair7": [1, 4], "lift": [1, 5, 8], "tair10": [1, 4], "hdy": 1, "2011": [1, 8], "95": 1, "southmiddleatlas_1d17": [1, 3], "african2epoch_1h18": [1, 3], "african3epoch_1h18": [1, 3], "msmc": 1, "khe32": 1, "ifr4": 1, "mountain": 1, "morocco": 1, "accur": [1, 4], "8th": 1, "last": [1, 4, 8], "30th": 1, "southmiddleatla": 1, "durvasula": [1, 7], "1073": 1, "pna": 1, "1616736114": 1, "73": 1, "989": 1, "121": 1, "796": 1, "1st": [1, 4], "165": 1, "210": 1, "2nd": [1, 4], "198": 1, "019": 1, "3rd": 1, "217": 1, "752": 1, "4th": 1, "228": 1, "222": 1, "5th": 1, "238": 1, "593": 1, "6th": 1, "246": 1, "984": 1, "7th": 1, "241": 1, "400": 1, "331": 1, "9th": 1, "181": 1, "571": 1, "10th": 1, "143456": 1, "11th": 1, "111": 1, "644": [1, 2], "12th": 1, "91": 1, "813": 1, "13th": 1, "83": 1, "829": 1, "14th": 1, "932": 1, "15th": 1, "87": 1, "661": 1, "16th": 1, "96": 1, "283": 1, "17th": 1, "745": 1, "18th": 1, "132": [1, 2], "19th": 1, "78": 1, "908": 1, "20th": 1, "537": [1, 2], "686": 1, "begin": [1, 3, 8], "119": 1, "341": 1, "954": 1, "517": 1, "610": 1, "693": 1, "151": 1, "590": 1, "173": 1, "502": 1, "139": 1, "426": 1, "879": 1, "362": 1, "541": 1, "307": 1, "540": 1, "260": 1, "520": [1, 2], "220": 1, "324": 1, "185": 1, "960": [1, 2], "156": 1, "584": 1, "131": 1, "471": [1, 2], "001": 1, "648": 1, "75": [1, 3], "958": 1, "62": 1, "544": [1, 8], "51": [1, 2], "077": 1, "spectrum": 1, "snp": [1, 8], "williamson": [1, 8], "2005": [1, 8], "methodolog": 1, "supplementari": 1, "huber": [1, 4], "2018": [1, 2, 8], "n_a": 1, "n_0": 1, "t_1": 1, "s41467": 1, "018": 1, "05281": 1, "746": 1, "148": 1, "218": 1, "568": 1, "344": 1, "n_2": 1, "n_3": 1, "t_2": 1, "t_3": 1, "161": 1, "744": 1, "076": 1, "203": 1, "420": 1, "534": 1, "araport11": 1, "cheng": 1, "dx": 1, "tpj": 1, "13415": 1, "deleteri": [1, 4, 8], "270": 1, "h": [1, 2, 3, 8], "500": 1, "bostau": [1, 2, 8], "62000": [1, 3], "158534110": 1, "26e": [1, 3], "136231102": 1, "121005158": 1, "120000601": 1, "120089316": 1, "117806340": 1, "110682743": 1, "113319770": 1, "105454467": 1, "103308737": 1, "106982474": 1, "87216183": 1, "83472345": 1, "82403003": 1, "85007780": 1, "81013979": 1, "73167244": 1, "65820629": 1, "63449741": 1, "71974595": 1, "69862954": 1, "60773035": 1, "52498615": 1, "62317253": 1, "42350435": 1, "51992305": 1, "45612108": 1, "45940150": 1, "51098607": 1, "139009144": 1, "16338": 1, "holsteinfriesian_1m13": [1, 2, 3], "holsteinfriesian_1b16": [1, 3], "fleckvieh_1b16": [1, 3], "jersey_1b16": [1, 3], "angus_1b16": [1, 3], "homozygos": 1, "observ": [1, 4, 8], "assumpt": [1, 4], "2213": 1, "94e": 1, "2221": 1, "2215": 1, "4a": 1, "s1": 1, "bull": 1, "walkwai": 1, "chief": 1, "mark": [1, 4], "hi": 1, "father": 1, "influentiu": 1, "sire": 1, "breed": 1, "larkin": 1, "www": [1, 8], "cgi": 1, "1114546109": 1, "holstein_friesian": 1, "1093": [1, 4], "molbev": [1, 4], "mst125": 1, "350": 1, "250": [1, 8], "90": 1, "154": 1, "354": 1, "754": 1, "654": 1, "454": 1, "0e": 1, "approxim": [1, 4], "bayesian": [1, 4], "comput": [1, 4, 7, 8], "linkag": [1, 8], "disequlibrium": 1, "minor": 1, "66e": 1, "exact": 1, "lead": [1, 8], "person": [1, 4], "commun": [1, 4, 7], "129": 1, "chose": 1, "52": 1, "australia": 1, "homogen": 1, "sub": [1, 4, 5], "kept": 1, "least": [1, 3, 4, 8], "inbr": 1, "unrel": 1, "1371": 1, "journal": [1, 7], "pgen": 1, "1005877": 1, "652": [1, 8], "65": 1, "485": 1, "86": 1, "206": 1, "79": 1, "079": 1, "71": 1, "209": 1, "841": 1, "63": 1, "092": 1, "882": 1, "726": [1, 2], "512": 1, "155": 1, "783": 1, "159": [1, 8], "602": 1, "367": 1, "892": 1, "815": 1, "320": 1, "793": 1, "999": 1, "043": 1, "53": 1, "045": 1, "881": 1, "638": 1, "817": 1, "821": 1, "629": 1, "287": 1, "455": [1, 8], "923": 1, "47": 1, "89e": 1, "43": 1, "70": 1, "789": 1, "85": 1, "607": 1, "82": 1, "448": 1, "844": 1, "920": [1, 8], "61": 1, "479": 1, "54": 1, "358": 1, "547": [1, 2], "963": 1, "176": 1, "604": 1, "546": 1, "414": 1, "689": 1, "184": 1, "395": 1, "812": 1, "227": 1, "275": 1, "856": [1, 2], "76": 1, "905": 1, "67": 1, "505": 1, "739": 1, "77": 1, "971": 1, "608": 1, "277": 1, "777": 1, "713": [1, 2], "549": 1, "460": 1, "474": 1, "106": 1, "704": 1, "640": 1, "947": 1, "561": 1, "388": 1, "00e": 1, "810": 1, "56": 1, "981": 1, "576": 1, "80": [1, 8], "651": [1, 8], "69": 1, "328": 1, "775": 1, "998": 1, "300": 1, "441": 1, "042": 1, "827": 1, "837": 1, "836": 1, "558": 1, "224": 1, "709": 1, "412": 1, "291": 1, "caeel": [1, 2, 8], "01": [1, 3, 4, 5], "fr\u00e9zal": 1, "f\u00e9lix": 1, "2015": 1, "barri\u00e8r": 1, "cutter": 1, "2006": 1, "15072434": 1, "12163e": 1, "84e": 1, "ii": [1, 3], "15279421": 1, "52929e": 1, "iii": [1, 3], "13783801": 1, "9066e": 1, "iv": [1, 3], "17493829": 1, "7121e": 1, "v": [1, 3, 7, 8], "20924180": 1, "47057e": 1, "17718942": 1, "94724e": 1, "mtdna": [1, 3], "13794": 1, "05e": 1, "2009": [1, 4, 8], "advanc": [1, 8], "intercross": 1, "genotyp": [1, 8], "1454": [1, 2], "nuclear": 1, "marker": 1, "236": [1, 8], "riail": 1, "qtl": 1, "though": [1, 8], "backcross": 1, "densiti": [1, 8], "suffici": [1, 4], "high": [1, 3], "emploi": 1, "littl": 1, "tip": [1, 4], "domain": 1, "breakpoint": 1, "ce11": 1, "gca_000002985": 1, "rockman": 1, "kruglyak": 1, "1000419": 1, "canfam": [1, 4, 8], "dog": 1, "13000": [1, 3], "lindblad": 1, "toh": 1, "122678785": 1, "636e": 1, "85426708": 1, "79852e": 1, "91889043": 1, "00087e": 1, "88276631": 1, "0523e": 1, "88915250": 1, "34433e": 1, "77573801": 1, "19219e": 1, "80974532": 1, "29347e": 1, "74330416": 1, "29131e": 1, "61074082": 1, "28772e": 1, "69331447": 1, "10715e": 1, "74389097": 1, "63945e": 1, "72498081": 1, "76106e": 1, "63241923": 1, "41302e": 1, "60966679": 1, "02812e": 1, "64190966": 1, "85675e": 1, "59632846": 1, "61406e": 1, "64289059": 1, "71883e": 1, "55844845": 1, "02993e": 1, "53741614": 1, "04251e": 1, "58134056": 1, "99097e": 1, "50858623": 1, "0339e": 1, "61439934": 1, "61505e": 1, "52294480": 1, "12664e": 1, "47698779": 1, "1146e": 1, "51628933": 1, "15437e": 1, "38964690": 1, "20846e": 1, "45876710": 1, "12603e": 1, "41182112": 1, "24636e": 1, "41845238": 1, "10136e": 1, "40214260": 1, "16876e": 1, "39895921": 1, "13977e": 1, "38810281": 1, "15559e": 1, "31377067": 1, "33394e": 1, "42124431": 1, "04838e": 1, "26524999": 1, "42991e": 1, "30810995": 1, "18752e": 1, "30902991": 1, "38346e": 1, "23914537": 1, "43637e": 1, "123869142": 1, "50648e": 1, "16727": 1, "pedigre": [1, 4], "237": 1, "sex": [1, 8], "163": 1, "labrador": 1, "greyhound": 1, "shapeit2": 1, "duohmm": 1, "campbel": 1, "1534": [1, 8], "g3": 1, "116": [1, 8], "034678": 1, "chlrei": [1, 8], "001141552511415525": [1, 3], "v\u00edtov\u00e1": 1, "3999999999999998e": [1, 3], "ness": 1, "8033585": 1, "74e": 1, "9223677": 1, "62e": 1, "9219486": 1, "4091191": 1, "47e": 1, "3500558": 1, "17e": 1, "9023763": 1, "6421821": 1, "5033832": 1, "98e": 1, "7956127": 1, "6576019": 1, "97e": 1, "27e": 1, "3826814": 1, "63e": 1, "9730733": 1, "55e": 1, "5206065": 1, "56e": 1, "4157777": 1, "9e": [1, 3], "96e": 1, "1922860": 1, "93e": 1, "7783580": 1, "71e": 1, "7188315": 1, "li": 1, "1720600": [1, 3], "gene": [1, 2, 4, 5], "convers": [1, 2, 4, 5, 8], "8299999999999998": 1, "518": 1, "23513712": 1, "40463e": 1, "25286936": 1, "23459e": 1, "28110227": 1, "7966e": 1, "32079331": 1, "71642e": 1, "1348131": 1, "23542271": 1, "89651e": 1, "y": [1, 3, 7], "3667352": 1, "mitochondrion_genom": [1, 3], "19524": 1, "meios": 1, "product": 1, "lab": 1, "highli": [1, 4], "860": 1, "femal": [1, 8], "calcul": [1, 2], "detect": [1, 4], "dm6": 1, "comeron": 1, "1002905": 1, "liftover_comeron2012": [1, 4], "winlen": [1, 4], "gapthresh": [1, 4], "useadjacentavg": [1, 4], "retainintermedi": [1, 4], "african3epoch_1s16": [1, 3, 8], "outofafrica_2l06": [1, 3], "sheehan": [1, 8], "song": [1, 8], "deep": 1, "train": 1, "due": [1, 4, 8], "psmc": 1, "2n": [1, 8], "msm": 1, "4n": 1, "faithfulli": 1, "afr": [1, 8], "pcbi": 1, "1004845": 1, "refer": [1, 4, 5, 8], "700": 1, "145": [1, 8], "200": [1, 4, 8], "onset": 1, "expans": 1, "stephan": 1, "eur": [1, 8], "0020166": 1, "720": 1, "600": [1, 2], "603": 1, "075": 1, "158": 1, "diverg": [1, 4], "45e": 1, "flybas": 1, "bdgp6": 1, "cd": [1, 2, 8], "hoskin": 1, "1101": 1, "gr": 1, "185579": 1, "114": 1, "mix": 1, "1619508114": 1, "74": 1, "330": 1, "ragsdal": [1, 7], "115": 1, "184812": 1, "meanlog": 1, "sdlog": 1, "360": [1, 2], "drosec": [1, 8], "05": [1, 3, 4, 5, 8], "legrand": 1, "100000": [1, 3, 8], "24956976": 1, "21536224": 1, "51e": 1, "28131630": 1, "88e": 1, "30464902": 1, "22909512": 1, "85e": 1, "1277805": 1, "esccol": [1, 8], "805175e": [1, 3], "sezonov": 1, "2007": [1, 4], "180000000": [1, 3], "hartl": 1, "moriyama": 1, "sawyer": 1, "1994": 1, "bacteri": [1, 3, 5], "542": [1, 3], "4641652": 1, "gasacu": [1, 8], "spine": 1, "stickleback": 1, "liu": 1, "29619991": 1, "11e": [1, 8], "23686546": 1, "17759012": 1, "34181212": 1, "15550311": 1, "18825451": 1, "30776923": 1, "20553084": 1, "20843631": 1, "17985176": 1, "17651971": 1, "20694444": 1, "20748428": 1, "16147532": 1, "17318724": 1, "19507025": 1, "20195758": 1, "15939336": 1, "20580295": 1, "20445003": 1, "17421465": 1, "15859692": 1, "16543": 1, "helann": [1, 8], "strasburg": 1, "rieseberg": 1, "673968": [1, 3], "2010": [1, 4], "149502186": 1, "174800439": 1, "176490873": 1, "208320189": 1, "178169690": 1, "148147350": 1, "149542083": 1, "167167940": 1, "189665024": 1, "181411567": 1, "189830405": 1, "163781230": 1, "173487274": 1, "173346949": 1, "175671323": 1, "206736614": 1, "195042445": 1, "helmel": [1, 8], "0958904109589041": [1, 3], "pardo": 1, "diaz": 1, "2111109": [1, 3], "17206585": 1, "9045316": 1, "10541528": 1, "9662098": 1, "9908586": 1, "14054175": 1, "14308859": 1, "9320449": 1, "8708747": 1, "31e": 1, "17965481": 1, "16e": 1, "11759272": 1, "16327298": 1, "18127314": 1, "08e": 1, "9174305": 1, "10235750": 1, "78e": 1, "10083215": 1, "14773299": 1, "16803890": 1, "16399344": 1, "14871695": 1, "13359691": 1, "tremblai": 1, "v\u00e9zina": 1, "2000": [1, 3, 8], "takahata": 1, "1993": 1, "248956422": [1, 8], "15235e": 1, "29e": [1, 3, 8], "242193529": 1, "10429e": 1, "198295559": 1, "12585e": 1, "190214555": 1, "1482e": 1, "181538259": 1, "12443e": 1, "170805979": 1, "12659e": 1, "159345973": 1, "17713e": 1, "145138636": 1, "16049e": 1, "138394717": 1, "21987e": 1, "133797422": 1, "33337e": 1, "135086622": 1, "17213e": 1, "133275309": 1, "30981e": 1, "114364328": 1, "3061e": 1, "107043718": 1, "36298e": 1, "101991189": 1, "73876e": 1, "90338345": 1, "48315e": 1, "83257441": 1, "55383e": 1, "80373285": 1, "46455e": 1, "58617616": 1, "83848e": 1, "64444167": 1, "67886e": 1, "46709983": 1, "72443e": 1, "50818468": [1, 8], "10572e": 1, "156040895": 1, "18483e": 1, "57227415": 1, "16569": 1, "hapmap": [1, 4, 8], "grch37": [1, 4], "grch38": [1, 8], "decod": [1, 8], "famili": [1, 8], "pyrho": 1, "acb": [1, 2], "asw": [1, 2], "beb": [1, 2], "cdx": [1, 2], "ch": [1, 2], "clm": [1, 2], "esn": [1, 2], "fin": [1, 2], "gbr": [1, 2], "gih": [1, 2], "gwd": [1, 2], "ib": [1, 2], "itu": [1, 2], "jpt": [1, 2], "khv": [1, 2], "lwk": [1, 2], "msl": [1, 2], "mxl": [1, 2], "pel": [1, 2], "pjl": [1, 2], "pur": [1, 2], "stu": [1, 2], "tsi": [1, 2], "project": [1, 4, 7], "million": 1, "four": [1, 4, 8], "ldhat": 1, "adjust": 1, "rearrang": 1, "readm": 1, "ftp": 1, "trace": 1, "ncbi": [1, 2], "nih": 1, "gov": 1, "1000genom": 1, "technic": 1, "work": [1, 2, 4, 6, 7, 8], "20110106_recombination_hotspot": 1, "nature06258": 1, "liftov": [1, 2, 4, 8], "liftover_catalog": [1, 4], "maintain": [1, 4, 7], "path_to_stdpopsim": 1, "chainfil": [1, 4], "path_to_chainfil": 1, "hg19tohg38": [1, 4], "chain": [1, 4], "gz": [1, 4, 8], "validationchain": [1, 4], "hg38tohg19": [1, 4], "257": [1, 8], "parent": [1, 8], "offspr": [1, 8], "pair": [1, 2, 8], "iceland": [1, 8], "289": [1, 8], "658": [1, 8], "combin": [1, 4, 8], "male": [1, 8], "com": [1, 4, 8], "addendum": [1, 8], "kong": 1, "nature09525": 1, "grch36": [1, 8], "hg18tohg38": 1, "henc": [1, 4], "separ": [1, 3, 4, 8], "infer": [1, 4, 8], "popgenmethod": 1, "smcpp": 1, "1126": [1, 4], "sciadv": 1, "aaw9206": 1, "spenc": [1, 7], "outofafricaextendedneandertaladmixturepulse_3i21": [1, 2, 3, 8], "outofafrica_2t12": [1, 2, 3, 8], "africa_1t12": [1, 3, 8], "americanadmixture_4b18": [1, 2, 3, 8], "outofafricaarchaicadmixture_5r19": [1, 3, 8], "zigzag_1s14": [1, 2, 3, 8], "ancienteurasia_9k19": [1, 3, 8], "papuansoutofafrica_10j19": [1, 2, 3, 8], "ashksub_7g19": [1, 2, 3, 8], "outofafrica_4j17": [1, 2, 3, 8], "africa_1b08": [1, 2, 3, 8], "ancienteurope_4a21": [1, 2, 3, 8], "iasi": [1, 7], "simpl": [1, 4, 6, 8], "1a": [1, 5], "unidirect": 1, "800": 1, "ky": 1, "yoruba": [1, 4], "utah": 1, "resid": [1, 4], "ceph": 1, "northern": 1, "western": 1, "ancestri": [1, 8], "nea": 1, "msab210": 1, "029": 1, "kya": 1, "290": 1, "ooa": [1, 8], "gutenkunst": [1, 4, 7, 8], "asian": [1, 8], "maximum": [1, 4, 8], "likelihood": [1, 4, 8], "variou": [1, 2, 4, 6, 8], "han": 1, "chines": 1, "beij": 1, "china": 1, "1000695": 1, "eu": 1, "AS": 1, "510": 1, "004": 1, "0055": 1, "848": 1, "35e": [1, 8], "tennessen": 1, "analysi": [1, 2, 4, 8], "jsf": 1, "23kya": 1, "fig": 1, "s5": 1, "fu": 1, "scienc": [1, 4, 7], "1219240": 1, "nature11690": 1, "310": [1, 8], "861": 1, "032": 1, "279": 1, "501": 1, "436": 1, "432": 1, "125": 1, "00307": 1, "0195": 1, "2st": 1, "0166": [1, 8], "040": 1, "204": [1, 8], "36e": [1, 8], "tennesen": [1, 4, 8], "brown": [1, 2, 8], "gravel": [1, 7, 8], "admix": [1, 8], "grew": [1, 8], "smaller": [1, 8], "asia": [1, 8], "1007385": 1, "1019276108": 1, "554": 1, "asn": 1, "0038": 1, "0048": 1, "emerg": 1, "percentag": 1, "amount": [1, 2, 4, 8], "popular": 1, "augment": 1, "contribut": [1, 4, 7], "eurasian": 1, "earli": 1, "put": [1, 8], "neanderth": 1, "branch": [1, 4], "symmetr": 1, "archaicafr": 1, "1008204": 1, "900": 1, "880": 1, "650": 1, "00125": 1, "00372": 1, "48": 1, "60": 1, "499": 1, "98": 1, "arch": 1, "nean": 1, "559": 1, "825": 1, "schiffel": [1, 2], "durbin": [1, 2], "terhorst": 1, "kamm": 1, "expand": [1, 7], "contract": 1, "ng": 1, "3015": 1, "560": [1, 2], "99448": 1, "00035977": 1, "0014391": 1, "005756": 1, "2rd": 1, "023025": 1, "3st": 1, "133": [1, 2], "533": 1, "333": 1, "dai": [1, 8], "momi2": 1, "input": [1, 8], "unsampl": 1, "basal": 1, "farmer": 1, "hunter": 1, "gather": 1, "sardinian": 1, "There": [1, 4, 6, 7, 8], "mbuti": 1, "addition": 1, "sever": [1, 2, 6, 8], "fossil": [1, 4], "date": [1, 3, 4, 8], "altai": 1, "prufer": 1, "mesolith": 1, "lazaridi": 1, "neolith": 1, "palaeolith": 1, "siberia": 1, "ma1": 1, "raghavan": 1, "ust": 1, "ishim": 1, "lbk": 1, "eef": 1, "loschbour": 1, "whg": 1, "upper": 1, "mal": 1, "ta": 1, "cultur": 1, "ustishim": 1, "1800": 1, "basaleurasian": 1, "1080": 1, "01621459": 1, "1635482": 1, "bazal": 1, "exp": 1, "340": 1, "696": 1, "44": [1, 4], "690": 1, "230": 1, "45": 1, "22e": 1, "ten": [1, 8], "denisovan": 1, "jacob": 1, "extens": [1, 4, 8], "malaspina": 1, "thu": [1, 4, 8], "indonesia": 1, "guinea": 1, "dena": 1, "2058": 1, "lineag": 1, "neaa": 1, "2612": 1, "den1": 1, "d1": 1, "introgress": 1, "den2": 1, "d2": 1, "nea1": 1, "1016": [1, 4], "cell": [1, 4], "02": [1, 5, 8], "035": 1, "nature18299": 1, "433": 1, "962": 1, "025": 1, "east": 1, "834": 1, "083": [1, 4], "826": [1, 2], "249": 1, "516": [1, 2], "41": 1, "563": [1, 2], "671": 1, "497": 1, "982": 1, "736": [1, 2], "64": 1, "322": [1, 8], "97": 1, "875": [1, 2], "282": 1, "750": [1, 2], "437": 1, "586": 1, "525": [1, 2], "231": 1, "243": 1, "394": [1, 2], "865": 1, "451": 1, "papaun": 1, "737": 1, "948": 1, "42": 1, "57": 1, "gladstein": [1, 7], "hammer": 1, "shown": [1, 4, 8], "mode": 1, "abc": 1, "s3": [1, 4], "ancestor": 1, "eastern": 1, "jew": 1, "experi": 1, "reduct": [1, 8], "flow": [1, 4], "arriv": 1, "group": [1, 4, 7, 8], "final": [1, 2, 4, 8], "moder": 1, "massiv": 1, "incorpor": [1, 4], "ascertain": 1, "me": 1, "waj": 1, "eaj": 1, "msz047": 1, "197": 1, "073": 1, "113": 1, "515": [1, 2], "aj": 1, "606": 1, "949": 1, "founder": 1, "105": 1, "850": [1, 8], "481": 1, "211": 1, "geneflow": 1, "jougan": 1, "joint": 1, "frequeci": 1, "af": 1, "exom": 1, "poulat": 1, "demographi": [1, 8], "previou": [1, 2, 4, 8], "japanes": 1, "program": [1, 3, 6, 7, 8], "moment": 1, "44e": 1, "tokyo": 1, "japan": 1, "117": 1, "200493": 1, "11293": 1, "23721": 1, "2831": 1, "b": [1, 3, 4, 7, 8], "2512": 1, "1019": 1, "4384": 1, "percent": 1, "8e": [1, 8], "75e": 1, "thousand": [1, 4], "357": 1, "46": 1, "boyko": [1, 8], "calibr": [1, 4, 8], "3e5": [1, 8], "chimp": [1, 8], "african_american": [1, 8], "1000083": 1, "778": 1, "636": 1, "809": 1, "80e": 1, "structur": [1, 4, 8], "demonstr": [1, 4, 8], "caucasu": 1, "anatolian": 1, "west": [1, 4], "yamnaya": 1, "stepp": 1, "rise": 1, "bronz": 1, "ag": 1, "throughout": 1, "1500": [1, 8], "ne": 1, "chg": 1, "ehg": 1, "yam": 1, "160": 1, "neo": 1, "180": 1, "135": 1, "allentoft": 1, "2022": [1, 5, 8], "04": [1, 8], "490594": 1, "140": 1, "25e": 1, "hunt": 1, "bay119": 1, "2023": [1, 7], "lethal": 1, "kim": [1, 4, 7, 8], "197145": [1, 8], "013": 1, "186": 1, "028": 1, "190": 1, "677": 1, "580": 1, "kyriazi": [1, 7, 8], "1086": 1, "726736": 1, "450": [1, 8], "010": 1, "050": 1, "inf": [1, 8], "musmu": [1, 2, 8], "mous": 1, "phifer": 1, "rixei": 1, "500000": [1, 3], "booker": 1, "keightlei": 1, "fujiwara": 1, "195154279": 1, "181755017": 1, "159745316": 1, "156860686": 1, "151758149": 1, "149588044": 1, "144995196": 1, "130127694": 1, "124359700": 1, "130530862": 1, "121973369": 1, "120092757": 1, "120883175": 1, "125139656": 1, "104073951": 1, "98008968": 1, "95294699": 1, "90720763": 1, "61420004": 1, "169476592": 1, "91455967": 1, "16299": 1, "775e": 1, "domesticuseurope_1f22": [1, 2, 3], "musculuskorea_1f22": [1, 2, 3], "castaneusindia_1f22": [1, 2, 3], "deu01": 1, "deu03": 1, "deu04": 1, "deu06": 1, "german": 1, "kazumichi": 1, "naoki": 1, "osada": 1, "graphic": [1, 4], "depict": 1, "m_musculus_domesticu": 1, "gbe": 1, "evac068": 1, "133912": 1, "98811": 1, "131050": 1, "173594": 1, "227037": 1, "279833": 1, "316861": 1, "327217": 1, "309961": 1, "271935": 1, "222951": 1, "173264": 1, "131392": 1, "101471": 1, "82953": 1, "73097": 1, "69317": 1, "69939": 1, "21th": 1, "74185": 1, "22th": 1, "81892": 1, "23th": 1, "93046": 1, "24th": 1, "107067": 1, "25th": 1, "121751": 1, "26th": 1, "132063": 1, "27th": 1, "131016": 1, "28th": 1, "115426": 1, "29th": 1, "90926": 1, "67337": 1, "31th": 1, "50557": 1, "32th": 1, "41195": 1, "33th": 1, "36886": 1, "34th": 1, "34163": 1, "35th": 1, "29931": 1, "36th": 1, "23419": 1, "37th": 1, "16490": 1, "38th": 1, "11240": 1, "39th": 1, "8332": 1, "40th": 1, "7480": 1, "41th": 1, "8463": 1, "42th": 1, "11758": 1, "43th": 1, "18939": 1, "44th": 1, "33028": 1, "45th": 1, "58488": 1, "46th": 1, "97250": 1, "47th": 1, "136620": 1, "48th": 1, "159142": 1, "49th": 1, "147212": 1, "50th": 1, "115399": 1, "51th": 1, "111242": 1, "52th": 1, "145603": 1, "53th": 1, "90428": 1, "54th": 1, "3844": 1, "55th": 1, "2040": 1, "56th": 1, "1915544": 1, "1654653": 1, "1429281": 1, "1234595": 1, "1066418": 1, "921140": 1, "795646": 1, "687237": 1, "593589": 1, "512693": 1, "442812": 1, "382446": 1, "330300": 1, "285254": 1, "246340": 1, "212726": 1, "183689": 1, "158606": 1, "136938": 1, "118221": 1, "102052": 1, "88084": 1, "76019": 1, "65596": 1, "56592": 1, "48815": 1, "42096": 1, "36292": 1, "31279": 1, "26948": 1, "23207": 1, "19975": 1, "17183": 1, "14772": 1, "12688": 1, "10889": 1, "9334": 1, "7991": 1, "6831": 1, "5829": 1, "4964": 1, "4216": 1, "3570": 1, "3012": 1, "2530": 1, "2114": 1, "1754": 1, "1443": 1, "1175": 1, "943": 1, "743": 1, "57th": 1, "kor01": 1, "kor02": 1, "kor03": 1, "kor05": 1, "korean": 1, "m_musculus_musculu": 1, "152757": 1, "407105": 1, "400867": 1, "359368": 1, "302950": 1, "245823": 1, "9thtime": 1, "194969": 1, "151909": 1, "116547": 1, "88494": 1, "67725": 1, "54304": 1, "47001": 1, "43933": 1, "43467": 1, "43874": 1, "42857": 1, "38441": 1, "30806": 1, "22556": 1, "16339": 1, "13023": 1, "12259": 1, "13588": 1, "16747": 1, "21219": 1, "25399": 1, "26648": 1, "23546": 1, "17741": 1, "12072": 1, "7990": 1, "5506": 1, "4177": 1, "3643": 1, "3751": 1, "4605": 1, "6695": 1, "11222": 1, "20382": 1, "36220": 1, "55959": 1, "68111": 1, "61935": 1, "42715": 1, "25527": 1, "16254": 1, "12104": 1, "9960": 1, "9029": 1, "8035": 1, "8931": 1, "179912": 1, "807711": 1, "697702": 1, "602670": 1, "520579": 1, "449667": 1, "388409": 1, "335491": 1, "289781": 1, "250293": 1, "216182": 1, "186716": 1, "161262": 1, "139274": 1, "120280": 1, "103872": 1, "89698": 1, "77455": 1, "66878": 1, "57741": 1, "49849": 1, "43031": 1, "37142": 1, "32054": 1, "27659": 1, "23863": 1, "20583": 1, "17750": 1, "15303": 1, "13189": 1, "11363": 1, "9785": 1, "8423": 1, "7246": 1, "6229": 1, "5350": 1, "4591": 1, "3936": 1, "3370": 1, "2881": 1, "2458": 1, "2093": 1, "1778": 1, "1505": [1, 2], "1270": 1, "1067": [1, 2], "891": 1, "740": 1, "609": 1, "495": 1, "398": [1, 2], "313": 1, "240": 1, "177": 1, "123": [1, 8], "ind03": 1, "ind04": 1, "indian": 1, "m_musculus_castaneu": 1, "castaneu": 1, "344802": 1, "463464": 1, "360433": 1, "275733": 1, "217017": 1, "182054": 1, "163295": 1, "155027": 1, "154098": 1, "159139": 1, "169657": 1, "185260": 1, "205098": 1, "227605": 1, "250544": 1, "271326": 1, "287572": 1, "297772": 1, "301783": 1, "300840": 1, "297138": 1, "293233": 1, "291560": 1, "294117": 1, "302369": 1, "317235": 1, "338818": 1, "365787": 1, "394606": 1, "418882": 1, "429975": 1, "420389": 1, "388298": 1, "338426": 1, "279816": 1, "222464": 1, "173419": 1, "134861": 1, "105533": 1, "83216": 1, "66260": 1, "53747": 1, "45372": 1, "41297": 1, "41845": 1, "47736": 1, "60911": 1, "86633": 1, "141377": 1, "291323": 1, "938111": 1, "5064712": 1, "64853": 1, "5585000": 1, "4955842": 1, "4397456": 1, "3901912": 1, "3462105": 1, "3071789": 1, "2725404": 1, "2417965": 1, "2145140": 1, "1903000": 1, "1688102": 1, "1497384": 1, "1328123": 1, "1177907": 1, "1044593": 1, "926277": 1, "821274": 1, "728084": 1, "645379": 1, "571979": 1, "506839": 1, "449026": 1, "397719": 1, "352184": 1, "311772": 1, "275907": 1, "244079": 1, "215830": 1, "190760": 1, "168510": 1, "148764": 1, "131239": 1, "115687": 1, "101884": 1, "89634": 1, "78762": 1, "69114": 1, "60551": 1, "52951": 1, "46207": 1, "40221": 1, "34909": 1, "30195": 1, "26011": 1, "22297": 1, "19002": 1, "16077": 1, "13481": 1, "11178": 1, "9133": 1, "7319": 1, "5709": 1, "4279": 1, "3011": 1, "1886": 1, "887": 1, "orysat": [1, 2, 8], "caicedo": 1, "46875": [1, 3], "43270923": 1, "490520": 1, "134525": 1, "35937250": 1, "36413819": 1, "35502694": 1, "29958434": 1, "31248787": 1, "29697621": 1, "28443022": 1, "23012720": 1, "23207287": 1, "29021106": 1, "27531856": 1, "bottleneckmigration_3c07": [1, 2, 3], "indica": 1, "tropic": 1, "japonica": 1, "ruf": 1, "rufipogon": 1, "ind": [1, 8], "trj": 1, "0030163": 1, "150": 1, "partial": [1, 4], "recoveri": 1, "pantro": [1, 2, 8], "chimpanze": 1, "langergrab": 1, "16781": [1, 3], "stevison": 1, "228573443": 1, "2a": [1, 3], "111504155": 1, "2b": [1, 3], "133216015": 1, "202621043": 1, "194502333": 1, "181907262": 1, "175400573": 1, "166211670": 1, "147911612": 1, "116767853": 1, "135926727": 1, "135753878": 1, "137163284": 1, "100452976": 1, "91965084": 1, "83230942": 1, "81586097": 1, "83181570": 1, "78221452": 1, "61309027": 1, "66533130": 1, "33445071": 1, "37823149": 1, "155549662": 1, "26350515": 1, "bonoboghost_4k19": [1, 2, 3], "kuhlwilm": [1, 2], "row": 1, "central": [1, 4], "extinct": 1, "among": [1, 4], "populatio": 1, "s41559": 1, "0881": 1, "11600": 1, "10200": 1, "3700": 1, "24900": 1, "8000": 1, "29100": 1, "65900": 1, "9200": 1, "015": 1, "005": 1, "3500": [1, 3], "1990": 1, "1200": [1, 2], "stop": [1, 4], "379": 1, "resiz": 1, "308": 1, "261": 1, "papanu": [1, 2, 8], "oliv": 1, "baboon": 1, "wu": 1, "335505": [1, 3], "wall": 1, "218172882": 1, "92638e": 1, "193660750": 1, "60544e": 1, "184919515": 1, "02238e": 1, "182120902": 1, "82513e": 1, "173900761": 1, "5798e": 1, "167138247": 1, "04979e": 1, "161768468": 1, "11888e": 1, "140274886": 1, "10899e": 1, "127591819": 1, "13288e": 1, "126462689": 1, "17532e": 1, "125913696": 1, "18403e": 1, "123343450": 1, "0824e": 1, "106849001": 1, "24677e": 1, "106654974": 1, "27419e": 1, "91985775": 1, "26084e": 1, "91184193": 1, "47616e": 1, "74525926": 1, "5241e": 1, "72894408": 1, "36841e": 1, "72123344": 1, "30374e": 1, "50021108": 1, "6772e": 1, "142711496": 1, "18898e": 1, "8309886": 1, "coloni": 1, "hous": [1, 4], "southwest": 1, "nation": 1, "primat": 1, "research": [1, 4], "center": 1, "snprc": 1, "evac040": 1, "singlepopsmcpp_1w22": [1, 2, 3], "panubis_snprc": 1, "93362": 1, "55968": 1, "72998": 1, "30714": 1, "41841": 1, "51822": 1, "120758": 1, "2046585": 1, "1219140": 1, "782017": 1, "432614": 1, "165305": 1, "5101": 1, "2434": 1, "phosin": [1, 2, 8], "robinson": 1, "taylor": 1, "185845356": 1, "178563925": 1, "174291665": 1, "146127150": 1, "139762554": 1, "115952311": 1, "115469292": 1, "110408561": 1, "106736052": 1, "102828027": 1, "104118372": 1, "90399378": 1, "90400161": 1, "89762611": 1, "88287594": 1, "85252673": 1, "79603858": 1, "79885847": 1, "59501331": 1, "58878645": 1, "35802323": 1, "131664873": 1, "vaquita2epoch_1r22": [1, 2, 3, 8], "evolv": 1, "kb": [1, 8], "did": [1, 4], "cpg": 1, "island": 1, "coverag": [1, 5], "60x": 1, "supp": 1, "s2": 1, "n_anc": 1, "n_curr": 1, "abm1742": 1, "807": 1, "162": 1, "morin": 1, "pipelin": [1, 4], "1755": 1, "0998": 1, "13284": 1, "026": 1, "ponab": [1, 8], "sumatran": 1, "wich": 1, "17900": [1, 3], "lock": 1, "227913704": 1, "72097e": 1, "109511694": 1, "74694e": 1, "129937803": 1, "08833e": 1, "193656255": 1, "77615e": 1, "189387572": 1, "06176e": 1, "179185813": 1, "87839e": 1, "169501136": 1, "89605e": 1, "145408105": 1, "82979e": 1, "144036388": 1, "34313e": 1, "112206110": 1, "04756e": 1, "132178492": 1, "94812e": 1, "128122151": 1, "79185e": 1, "132184051": 1, "04316e": 1, "98475126": 1, "40817e": 1, "88963417": 1, "11075e": 1, "82547911": 1, "6315e": 1, "68237989": 1, "76066e": 1, "75914007": 1, "01983e": 1, "75923960": 1, "40065e": 1, "57575784": 1, "09647e": 1, "60841859": 1, "31424e": 1, "34683425": 1, "58867e": 1, "35308119": 1, "83628e": 1, "151242693": 1, "40288e": 1, "16499": 1, "nater": 1, "pygmaeu": 1, "cub": 1, "047": 1, "ponabe2": 1, "ponabe3": 1, "bornean": 1, "twospecies_2l11": [1, 3], "decai": [1, 8], "grow": [1, 2, 8], "slightli": [1, 4, 8], "nature09687": 1, "934": 1, "617": 1, "317": 1, "805": 1, "157": 1, "straga": [1, 8], "0027397260273972603": [1, 3], "savageau": 1, "1983": 1, "140000": [1, 3], "da": 1, "cunha": 1, "120000": [1, 3], "2065074": 1, "53e": [1, 3], "offer": 1, "updat": [2, 4, 6], "activ": [2, 4, 6, 8], "error": [2, 4, 6, 8], "gamma_k17": [2, 3, 4, 8], "dfe": [2, 3, 5], "ryangutenkunst": 2, "1478": 2, "engin": [2, 3, 4, 5, 6], "led": 2, "declin": 2, "small": [2, 4, 8], "model": [2, 3, 5, 7], "petrelharp": 2, "1622": 2, "demograph": [2, 3, 5, 7], "americanadmixture_4b11": 2, "now": [2, 4, 8], "old": 2, "throw": [2, 8], "deprec": 2, "1603": 2, "time_unit": 2, "gener": [2, 3, 4, 5, 7], "avoid": 2, "mismatch": 2, "nspope": 2, "1567": 2, "As": [2, 4, 7, 8], "behavior": 2, "original_coordin": 2, "basic_contig": 2, "1570": 2, "might": [2, 4, 8], "underli": 2, "top": [2, 4, 8], "level": [2, 4, 6, 8], "affect": [2, 4, 8], "anyon": [2, 8], "who": [2, 4, 7], "pars": [2, 4], "relat": [2, 4, 8], "sweep": [2, 5], "infrastructur": [2, 4], "move": 2, "namespac": 2, "proper": 2, "featur": [2, 4, 7, 8], "1498": 2, "mu": [2, 3, 5, 8], "musculu": [2, 3, 5, 8], "peterdfield": 2, "1437": 2, "igronau": 2, "orzya": 2, "sativa": [2, 3, 5, 8], "ornobalam": 2, "1453": 2, "minesrebollo": 2, "1461": 2, "phocoena": [2, 3, 5], "sinu": [2, 3, 5], "1514": 2, "ckyriazi": 2, "1538": 2, "lognormal_h17": [2, 3], "1480": 2, "mixed_k23": [2, 3, 8], "chriscrsmith": 2, "gamma_r22": [2, 3], "1547": 2, "1560": 2, "1492": 2, "1485": 2, "1531": 2, "1524": 2, "1526": 2, "1520": 2, "releas": [2, 5], "grahamgow": 2, "chr4": [2, 3, 8], "izabelcavassim": 2, "1092": 2, "incorrectli": 2, "1345": 2, "api": [2, 3, 4, 5], "jeromekelleh": [2, 4], "1361": 2, "aed": [2, 3, 5, 8], "aegypti": [2, 3, 4, 5, 8], "manolofperez": 2, "871": 2, "893": 2, "ana": [2, 3, 5, 8], "platyrhyncho": [2, 3, 5, 8], "1070": 2, "anoli": [2, 3, 5, 8], "carolinensi": [2, 3, 5, 8], "vcaudil": 2, "874": 2, "andrewkern": [2, 4], "896": 2, "anophel": [2, 3, 5, 8], "gambia": [2, 3, 5, 8], "906": 2, "mellifera": [2, 3, 5, 8], "janaobstet": 2, "1025": 2, "1268": 2, "bo": [2, 3, 5, 8], "tauru": [2, 3, 5, 8], "gtsambo": 2, "1269": 2, "caenorhabd": [2, 3, 5, 8], "elegan": [2, 3, 5, 8], "attrna": 2, "910": 2, "1265": 2, "chlamydomona": [2, 3, 5, 8], "reinhardtii": [2, 3, 5, 8], "aai": 2, "drosophila": [2, 3, 5], "sechellia": [2, 3, 5, 8], "jradrion": 2, "872": 2, "vitorpavinato": 2, "1264": 2, "gasterosteu": [2, 3, 5, 8], "aculeatu": [2, 3, 5, 8], "1105": 2, "1253": 2, "helianthu": [2, 3, 5, 8], "annuu": [2, 3, 5, 8], "1218": 2, "xin": [2, 7], "huang": [2, 7], "1250": 2, "heliconiu": [2, 3, 5, 8], "melpomen": [2, 3, 5, 8], "percyf": 2, "870": 2, "noscod": 2, "1165": 2, "pan": [2, 3, 5], "troglodyt": [2, 3, 5], "1215": 2, "1291": 2, "papio": [2, 3, 5], "anubi": [2, 3, 5], "saurabhbelsar": 2, "1216": 2, "mufernando": 2, "1263": 2, "streptococcu": [2, 3, 5], "agalactia": [2, 3, 5], "jeanrjc": 2, "854": 2, "1251": 2, "883": 2, "1021": [2, 8], "1279": 2, "1272": 2, "leonardolasi": 2, "1066": 2, "awohn": 2, "1259": 2, "rwapl": 2, "jeffspenc": 2, "1246": 2, "993": 2, "995": 2, "alipearson": 2, "941": 2, "1256": 2, "1370": 2, "1261": 2, "rockmanriail_ce11": [2, 3], "comeroncrossoverv2_dm6": [2, 3, 4], "592": 2, "hapmapii_grch38": [2, 3, 8], "1301": 2, "decodesexaveraged_grch38": [2, 3, 8], "pyrhoxxx_grch38": 2, "572": 2, "575": 2, "xxx": 2, "pyrho_panubis1_0": [2, 3], "1002": 2, "plu": 2, "930": [2, 8], "1152": 2, "462": 2, "1341": 2, "fbaumdick": 2, "1106": 2, "1355": 2, "apragsdal": 2, "664": 2, "arbitrari": [2, 8], "1348": 2, "keyword": [2, 7], "764": 2, "1326": 2, "839": 2, "1356": 2, "messag": [2, 3, 4], "cli": [2, 5], "equival": [2, 8], "still": [2, 4, 8], "rais": [2, 8], "help": [2, 3, 4, 7, 8], "1052": 2, "1117": 2, "qualiti": [2, 3, 4], "1292": 2, "pull": [2, 4, 7], "autom": [2, 4], "790": 2, "templat": [2, 4], "772": 2, "tool": [2, 8], "574": 2, "araport_11": 2, "1327": 2, "flybase_bdgp6": [2, 3], "32": [2, 3], "1042": 2, "ensembl_havana_104": 2, "gamma_h17": [2, 3], "1046": [2, 8], "lognormalpluspositive_r16": [2, 3], "1178": 2, "1099": 2, "import": [2, 4, 8], "bugfix": 2, "recommend": [2, 4, 6], "signific": 2, "repeat": 2, "analys": [2, 4, 5], "correct": 2, "off": [2, 4], "african": [2, 8], "european": [2, 8], "continu": [2, 4], "ancient": [2, 8], "period": [2, 8], "496": 2, "ndukler": 2, "527": 2, "requir": [2, 3, 4, 5, 8], "attr": 2, "399": 2, "cani": [2, 3, 5, 8], "familiari": [2, 3, 5, 8], "375": 2, "pongo": [2, 3, 4, 5], "abelii": [2, 3, 5], "363": 2, "372": 2, "387": 2, "agladstein": 2, "494": 2, "536": 2, "409": 2, "392": 2, "407": 2, "aw": [2, 4], "514": 2, "335": [2, 8], "477": 2, "quiet": [2, 3], "q": [2, 3, 8], "chrm": [2, 3], "528": 2, "405": 2, "temporarili": 2, "ponpyg": 2, "pin": 2, "packag": [2, 4, 6, 8], "problem": [2, 4], "366": 2, "jgallowa07": 2, "359": 2, "multi": [2, 4], "365": 2, "cache_dir": [3, 8], "subcommand": 3, "exit": 3, "essenti": [3, 4, 8], "dir": [3, 4], "environ": [3, 6, 7, 8], "stdpopsim_cach": 3, "home": 3, "runner": 3, "binari": [3, 6, 8], "redirect": [3, 8], "filenam": [3, 4, 8], "782e": 3, "help_model": [3, 8], "bibtex_fil": [3, 8], "l": [3, 7, 8], "accept": 3, "depend": [3, 6], "bib": 3, "overwrit": 3, "dry": [3, 8], "actual": [3, 8], "chr1": [3, 4, 8], "chr2": 3, "chr3": 3, "leftmost": 3, "rightmost": 3, "automat": [3, 4, 6, 8], "anyth": [3, 8], "comma": 3, "433e": 3, "chr5": 3, "chr6": 3, "chr7": 3, "chr8": 3, "chr9": 3, "chr10": 3, "chr11": 3, "chr12": 3, "chr13": 3, "chr14": 3, "chr15": 3, "chr16": 3, "chr17": 3, "chr18": 3, "chr19": 3, "chr20": [3, 8], "chr21": 3, "chr23": 3, "chr24": 3, "chr25": 3, "chr26": 3, "chr27": 3, "chr28": 3, "chr29": 3, "chr30": 3, "chrz": 3, "chr31": 3, "chr32": 3, "chr33": 3, "chr34": 3, "chr35": 3, "chr36": 3, "chr37": 3, "chr38": 3, "chr39": 3, "chr40": 3, "447e": 3, "chr2l": [3, 4, 8], "chr2r": 3, "chr3l": 3, "chr3r": 3, "chrx": 3, "318e": 3, "nc_037638": 3, "nc_037639": 3, "nc_037640": 3, "nc_037641": 3, "nc_037642": 3, "nc_037643": 3, "nc_037644": 3, "nc_037645": 3, "nc_037646": 3, "nc_037647": 3, "nc_037648": 3, "nc_037649": 3, "nc_037650": 3, "nc_037651": 3, "nc_037652": 3, "nc_037653": 3, "nc_001566": 3, "arabidopsi": [3, 4, 5, 8], "thaliana": [3, 4, 5, 8], "029e": 3, "help_genetic_map": [3, 8], "help_df": [3, 8], "help_annot": [3, 8], "salomeaveraged_tair10": [3, 4, 8], "popsim": [3, 4, 7], "io": 3, "doc": 3, "html": [3, 4], "gamma_h18": 3, "araport_11_exon": 3, "araport_11_cd": 3, "854e": 3, "053e": 3, "506e": 3, "campbell2016_canfam3_1": 3, "351e": 3, "459e": 3, "melanogast": [3, 4, 5], "085e": 3, "comeroncrossover_dm6": 3, "chry": 3, "51_exon": 3, "51_cd": 3, "223e": 3, "escherichia": [3, 5, 8], "001e": 3, "966e": 3, "253e": 3, "hapmapii_grch37": [3, 4], "decodesexaveraged_grch36": [3, 8], "pyrhoacb_grch38": 3, "pyrhoasw_grch38": 3, "pyrhobeb_grch38": 3, "pyrhocdx_grch38": 3, "pyrhoceu_grch38": 3, "pyrhochb_grch38": 3, "pyrhochs_grch38": 3, "pyrhoclm_grch38": 3, "pyrhoesn_grch38": 3, "pyrhofin_grch38": 3, "pyrhogbr_grch38": 3, "pyrhogih_grch38": 3, "pyrhogwd_grch38": 3, "pyrhoibs_grch38": 3, "pyrhoitu_grch38": 3, "pyrhojpt_grch38": 3, "pyrhokhv_grch38": 3, "pyrholwk_grch38": 3, "pyrhomsl_grch38": 3, "pyrhomxl_grch38": 3, "pyrhopel_grch38": 3, "pyrhopjl_grch38": 3, "pyrhopur_grch38": 3, "pyrhostu_grch38": 3, "pyrhotsi_grch38": 3, "pyrhoyri_grch38": 3, "ensembl_havana_104_exon": [3, 8], "ensembl_havana_104_cd": [3, 8], "567e": 3, "oryza": [3, 5, 8], "955e": 3, "chr2a": 3, "chr2b": 3, "124e": 3, "phocoena_sinu": 3, "mphosin1": 3, "pri": 3, "110_exon": 3, "110_cd": 3, "403e": 3, "naterpa_ponabe3": 3, "naterpp_ponabe3": 3, "them": [3, 4, 8], "alreadi": [3, 4, 8], "effort": [4, 7], "welcom": [4, 7], "envis": 4, "contributor": [4, 7], "curat": 4, "biologist": 4, "great": [4, 8], "step": [4, 5, 8], "ins": 4, "establish": 4, "benchmark": [4, 7], "align": 4, "goal": [4, 7], "confus": 4, "edit": [4, 8], "contact": [4, 7], "subscrib": [4, 7], "email": [4, 7], "serv": [4, 7], "comment": [4, 7], "lot": [4, 7, 8], "chatter": [4, 7], "ve": [4, 7, 8], "cooper": [4, 7], "want": [4, 8], "don": 4, "look": [4, 8], "good": [4, 8], "And": [4, 8], "importantli": 4, "conduct": [4, 7], "sure": [4, 6, 8], "fork": 4, "repo": 4, "clone": 4, "instruct": [4, 6], "librari": [4, 6, 7, 8], "later": [4, 6, 8], "pip": [4, 5], "python3": [4, 6], "txt": 4, "conda": [4, 5], "forg": [4, 6], "channel": [4, 6], "config": [4, 6], "troubl": 4, "try": [4, 6, 8], "pip3": 4, "encourag": [4, 7], "venv": 4, "stdpopsim_env": 4, "next": [4, 8], "bin": 4, "prompt": 4, "deactiv": 4, "repositori": 4, "copi": [4, 8], "hook": 4, "upstream": 4, "remot": 4, "topic": 4, "reliabl": [4, 6], "recip": 4, "git": 4, "fetch": 4, "checkout": 4, "topic_branch_nam": 4, "re": [4, 8], "open": [4, 7, 8], "gotten": 4, "On": [4, 8], "violat": 4, "style": 4, "find": [4, 7, 8], "reformat": 4, "modifi": [4, 8], "made": [4, 8], "stage": 4, "unstag": 4, "bypass": 4, "feedback": 4, "progress": 4, "verifi": [4, 8], "basic": [4, 6, 8], "task": [4, 8], "messi": 4, "clean": 4, "squash": 4, "visualis": 4, "network": [4, 7], "view": 4, "let": [4, 8], "graph": [4, 8], "decor": 4, "onelin": 4, "someth": [4, 8], "923ab2": 4, "mcveanlab": 4, "0190a92": 4, "2a5fc09": 4, "outlin": 4, "1ccb970": 4, "c49601f": 4, "better": 4, "fab9310": 4, "62c9560": 4, "tidi": 4, "51e21e8": 4, "6fff557": 4, "modul": [4, 5], "90d6367": 4, "concept": 4, "e2aaf95": 4, "debug": 4, "info": [4, 8], "2fbdfdc": 4, "badg": 4, "circleci": 4, "codecov": 4, "c66b575": 4, "ci": 4, "3ae454f": 4, "circl": 4, "c39415a": 4, "dd47000": 4, "recomb": 4, "nice": 4, "linear": 4, "consist": 4, "meaning": 4, "ideal": 4, "aim": 4, "achiev": [4, 8], "rewrit": 4, "never": 4, "caus": 4, "idea": [4, 8], "bisect": 4, "easier": [4, 7, 8], "nois": 4, "97a9458": 4, "c9c4a28": 4, "ad4c807": 4, "0fe6dc4": 4, "520e6ac": 4, "20fb835": 4, "port": 4, "tennyson": 4, "b3d45ea": 4, "quickli": [4, 8], "79d26b4": 4, "fly_model": 4, "doesn": [4, 8], "against": 4, "interact": 4, "editor": [4, 7], "pick": 4, "onto": 4, "p": [4, 7, 8], "reword": 4, "amend": 4, "meld": 4, "fixup": 4, "discard": 4, "exec": 4, "shell": 4, "drop": 4, "bottom": 4, "THAT": 4, "WILL": 4, "BE": 4, "everyth": 4, "abort": 4, "success": 4, "screen": 4, "enter": 4, "tue": 4, "mar": 4, "00": 4, "0000": 4, "No": [4, 8], "rst": 4, "delet": 4, "session": [4, 8], "detach": 4, "6b8a2a5": 4, "insert": [4, 8], "successfulli": 4, "ref": [4, 8], "forc": 4, "push": 4, "mislead": 4, "fast": [4, 8], "fail": 4, "hint": 4, "behind": 4, "counterpart": 4, "integr": 4, "again": [4, 8], "NOT": 4, "listen": 4, "TO": 4, "IN": 4, "terribl": 4, "advic": 4, "mess": [4, 8], "replac": 4, "state": [4, 8], "delta": 4, "thread": 4, "kib": 4, "mib": 4, "reus": 4, "d033ffa": 4, "ok": 4, "just": [4, 8], "sometim": [4, 8], "frustrat": 4, "loop": 4, "undo": [4, 8], "explan": 4, "go": [4, 8], "topic_branch": 4, "a3": 4, "realli": 4, "pain": 4, "togeth": [4, 7], "said": 4, "irrevers": 4, "backup": 4, "topic_backup": 4, "diff": [4, 8], "diagram": 4, "patch": 4, "root": [4, 8], "fresh": 4, "test_branch": 4, "p1": 4, "reset": 4, "revers": 4, "oper": 4, "noth": 4, "bad": 4, "facilit": 4, "divers": [4, 7, 8], "That": 4, "certain": [4, 6, 8], "everi": [4, 8], "unsur": 4, "baselin": 4, "think": [4, 8], "discuss": [4, 8], "fill": 4, "solut": 4, "characterist": 4, "Of": [4, 8], "cours": [4, 8], "precis": 4, "practic": [4, 7, 8], "guidelin": 4, "compon": 4, "brief": 4, "action": [4, 7], "incomplet": [4, 7], "scaffold": 4, "accumul": 4, "compar": [4, 8], "phylogenet": 4, "variat": [4, 8], "direct": 4, "hopefulli": 4, "fine": 4, "vari": [4, 7, 8], "nonetheless": [4, 8], "furthermor": [4, 8], "histor": 4, "captur": [4, 8], "presenc": 4, "natur": 4, "knowledg": 4, "typic": 4, "mention": 4, "question": 4, "assist": 4, "member": [4, 7], "brows": 4, "hesit": 4, "happi": 4, "answer": 4, "relev": [4, 8], "subdirectori": 4, "devot": 4, "six": 4, "charact": 4, "unless": 4, "explicitli": 4, "util": 4, "_": [4, 8], "arabidopsis_thaliana": 4, "insid": 4, "species_id": 4, "__init__": 4, "load": [4, 8], "physic": 4, "slot": 4, "probabl": [4, 8], "accompani": 4, "test_": 4, "summar": 4, "_genom": 4, "_speci": 4, "1000genomesconsortium": 4, "webpag": 4, "citereason": 4, "rec_rat": 4, "mut_rat": 4, "pop_siz": 4, "gen_tim": 4, "auxiliari": 4, "mitochondri": 4, "plastid": 4, "chromsoom": 4, "mbe": 4, "_rho": 4, "1e6": [4, 8], "_ne": 4, "124000": 4, "_mean_recombination_r": 4, "_recombination_r": 4, "ossowski": 4, "_mean_mutation_r": 4, "_mutation_r": 4, "_species_ploidi": 4, "_ploidi": 4, "1180677": 4, "msu247": 4, "nar": 4, "gkm965": 4, "swarbreck": 4, "10_000": 4, "1890": 4, "0012": 4, "9658": 4, "1006": 4, "gtinso": 4, "co": 4, "2016": [4, 8], "063": 4, "newli": [4, 8], "pytest": 4, "blank": 4, "disabl": [4, 8], "someon": 4, "els": [4, 8], "offici": 4, "team": 4, "undergo": 4, "fulli": [4, 6, 8], "stai": [4, 8], "tune": 4, "settl": 4, "discrep": 4, "whenev": 4, "core": 4, "meet": 4, "consid": 4, "provision": 4, "simpli": [4, 8], "press": 4, "purpos": [4, 8], "consider": 4, "checklist": 4, "volunt": 4, "intent": 4, "duplic": 4, "partit": 4, "aspect": [4, 8], "examin": 4, "involv": [4, 5], "understand": [4, 8], "uncertain": 4, "inconsist": 4, "confid": 4, "choos": 4, "blind": 4, "interpret": 4, "reach": [4, 8], "agreement": 4, "ambigu": 4, "decis": 4, "clearli": 4, "accordingli": 4, "rational": [4, 8], "consensu": 4, "block": 4, "recal": [4, 8], "skip": 4, "yet": [4, 8], "parametr": 4, "def": 4, "test_recombination_r": 4, "self": 4, "assert": 4, "approx": 4, "kei": 4, "test_aedaeg": 4, "306e": 4, "249e": 4, "291e": 4, "invok": 4, "misspecif": 4, "unrealist": 4, "downstream": [4, 8], "clear": 4, "seri": 4, "primarili": 4, "suggest": 4, "decid": [4, 8], "special": 4, "add_demographic_model": 4, "_model_func_nam": 4, "population_configur": 4, "migration_matrix": 4, "demographic_ev": 4, "eleven": 4, "eight": 4, "quit": [4, 8], "straightforward": [4, 8], "hand": 4, "camel": 4, "underscor": 4, "textual": 4, "paragraph": 4, "panel": 4, "yoruban": 4, "cite": [4, 7], "dem_model": 4, "bake": 4, "uncommon": 4, "specifc": 4, "ratio": [4, 8], "admixtur": [4, 8], "plausibl": [4, 8], "posterior": 4, "parameter_t": 4, "model_id": 4, "csv": 4, "properli": 4, "_build": 4, "confirm": 4, "okai": 4, "statement": 4, "parallel": 4, "_model_id_": 4, "_your_review_funct": 4, "term": [4, 7, 8], "enough": [4, 8], "slow": 4, "upload": 4, "delimit": 4, "programat": 4, "definit": [4, 5], "exactli": [4, 8], "32807": 4, "016134": 4, "488426": 4, "579949": 4, "tar": 4, "gzip": [4, 8], "archiv": 4, "tarbal": 4, "flat": [4, 8], "sent": 4, "placement": 4, "cloud": 4, "approv": 4, "_genetic_map_cit": 4, "fill_m": 4, "9999": 4, "gen_map": 4, "field": 4, "_gm": 4, "amazonaw": 4, "name_": 4, "_more_nam": 4, "add_genetic_map": 4, "sha256sum": 4, "gnu": 4, "coreutil": 4, "tgz": 4, "wait": 4, "whom": 4, "send": 4, "andrew": [4, 7], "kern": [4, 7], "him": 4, "hardcod": 4, "receiv": 4, "expect": [4, 8], "resourc": [4, 8], "filename_v1": 4, "whatev": 4, "increment": 4, "remap": 4, "hg19": 4, "window": [4, 6, 8], "threshold": 4, "gap": 4, "adjac": 4, "usechromosomeavg": 4, "plot": 4, "liftover_valid": 4, "intermedi": 4, "inspect": 4, "liftover_intermedi": 4, "retaininermedi": 4, "deem": 4, "proce": 4, "albeit": 4, "minimap2": 4, "paftool": 4, "js": 4, "_dfe_func_nam": 4, "accord": 4, "0004": 4, "distributoin": 4, "p_neutral": 4, "p_neg": 4, "299": 4, "p_posit": 4, "finish": 4, "convinc": [4, 8], "potenti": [4, 8], "er": 4, "readabl": 4, "pep8": 4, "guid": 4, "89": 4, "suit": 4, "strict": 4, "first_3_letters_genu": 4, "first_3_letters_speci": 4, "capitil": 4, "familiar": 4, "camelcasedescriptivenam": 4, "somethingdescript": 4, "number_of_popul": 4, "first_author_initi": 4, "two_digit_d": 4, "meant": 4, "crash": 4, "etc": [4, 8], "necessarili": 4, "collis": 4, "similarli": 4, "first_authors_last_name_first_lett": 4, "sens": [4, 8], "few": [4, 8], "power": 4, "flake8": 4, "permit": 4, "whitespac": 4, "offend": 4, "renam": 4, "cov": 4, "straightfoward": 4, "web": 4, "htmlcov": 4, "highlight": 4, "red": 4, "restructuredtext": 4, "markup": 4, "sphinx": 4, "changelog": [4, 5], "ui": 4, "sdist": 4, "setuptools_scm": 4, "appopri": 4, "pypi": 4, "twine": 4, "dist": 4, "tag": 4, "symlink": 4, "feedstock": 4, "introduct": [5, 8], "licenc": 5, "instal": [5, 7, 8], "quick": [5, 8], "workflow": 5, "standard": [5, 7], "2024": 5, "06": [5, 7, 8], "search": [5, 8], "awai": [6, 8], "jupyt": 6, "binder": 6, "particularli": [6, 8], "osx": 6, "linux": 6, "miniconda": 6, "anaconda": 6, "virtual": 6, "compil": 6, "guarante": 6, "regular": 6, "unix": 6, "dataset": 7, "hood": 7, "reli": [7, 8], "skim": [7, 8], "softwar": 7, "scientist": 7, "especi": 7, "underrepres": 7, "popgen": 7, "largest": 7, "commit": 7, "friendli": 7, "safe": [7, 8], "gender": 7, "sexual": 7, "orient": 7, "abil": [7, 8], "ethnic": 7, "socioeconom": 7, "statu": 7, "religion": 7, "lack": 7, "thereof": 7, "Being": 7, "valuabl": 7, "avenu": 7, "career": 7, "manuscript": 7, "followup": 7, "jeffrei": 7, "adrion": 7, "christoph": 7, "cole": 7, "noah": 7, "dukler": 7, "jare": 7, "gallowai": 7, "ariella": 7, "graham": 7, "gower": 7, "aaron": 7, "georgia": 7, "tsambo": 7, "franz": 7, "baumdick": 7, "jedidiah": 7, "carlson": 7, "reed": 7, "cartwright": 7, "arun": 7, "ilan": 7, "gronau": 7, "bernard": 7, "patrick": 7, "mckenzi": 7, "philipp": 7, "messer": 7, "ekaterina": 7, "noskova": 7, "diego": 7, "ortega": 7, "del": 7, "vecchyo": 7, "fernando": 7, "racimo": 7, "travi": 7, "struck": 7, "simon": 7, "ryan": 7, "kirk": 7, "lohmeul": 7, "peter": 7, "ralph": 7, "daniel": 7, "schrider": 7, "adam": 7, "siepel": 7, "jerom": 7, "kelleh": 7, "elif": 7, "e54967": 7, "7554": 7, "54967": 7, "elis": 7, "lauterbur": 7, "maria": 7, "izabel": 7, "cavassim": 7, "nathaniel": 7, "pope": 7, "jeff": 7, "saurabh": 7, "belsar": 7, "arjun": 7, "biddanda": 7, "victoria": 7, "caudil": 7, "jean": 7, "curi": 7, "ignacio": 7, "echevarria": 7, "benjamin": 7, "haller": 7, "ahm": 7, "hasan": 7, "leonardo": 7, "nicola": 7, "martin": 7, "jana": 7, "ob\u0161tet": 7, "vitor": 7, "antonio": 7, "corr\u00eaa": 7, "pavinato": 7, "alic": 7, "pearson": 7, "david": 7, "peed": 7, "manolo": 7, "perez": 7, "murillo": 7, "rodrigu": 7, "chri": 7, "smith": 7, "anastasia": 7, "teterina": 7, "sila": 7, "titt": 7, "unneberg": 7, "juan": 7, "manuel": 7, "vazquez": 7, "wapl": 7, "anthoni": 7, "wilder": 7, "wohn": 7, "yan": 7, "wong": 7, "gregor": 7, "gorjanc": 7, "lesson": 7, "realist": [7, 8], "rp84874": 7, "84874": 7, "articl": 7, "article_typ": 7, "titl": [7, 8], "lohmuel": 7, "coop": 7, "wittkopp": 7, "patricia": 7, "novembr": 7, "john": 7, "sethuraman": 7, "mathieson": 7, "sara": 7, "volum": 7, "month": 7, "jun": 7, "pub_dat": 7, "issn": 7, "2050": 7, "084x": 7, "ltd": 7, "ob": 7, "teter": 7, "corr": 7, "gplv3": 7, "licens": 7, "complic": 8, "walk": 8, "nest": 8, "context": 8, "trait": 8, "seen": 8, "foo": 8, "syntax": 8, "rememb": 8, "termin": 8, "truncat": 8, "american": 8, "10000000": 8, "20000000": 8, "scenario": 8, "compact": 8, "effici": 8, "genealog": 8, "analyz": 8, "pretti": 8, "fifti": 8, "ls": 8, "lth": 8, "rw": 8, "natep": 8, "6g": 8, "oct": 8, "03": 8, "163m": 8, "zip": 8, "tszip": 8, "reduc": 8, "49m": 8, "tsz": 8, "103m": 8, "swap": 8, "didn": 8, "big": 8, "unlik": 8, "minut": 8, "whera": 8, "upward": 8, "briefli": 8, "speedup": 8, "accomplish": 8, "drift": 8, "disequilibrium": 8, "faster": 8, "fewer": 8, "seem": 8, "indistinguish": 8, "awar": 8, "subtl": 8, "urrichio": 8, "hernandez": 8, "conver": 8, "bundl": 8, "ex": 8, "cat": 8, "14500000": 8, "15000000": 8, "30002425": 8, "30002430": 8, "30003000": 8, "14001000": 8, "14005000": 8, "suppli": 8, "silent": 8, "perus": 8, "arm": 8, "extrem": 8, "nervou": 8, "prepend": 8, "vv": 8, "helpfulli": 8, "grep": 8, "2214454132353": 8, "runinitializecallback": 8, "initializemutationtyp": 8, "initializegenomicelementtyp": 8, "m0": 8, "initializegenomicel": 8, "g0": 8, "999999": 8, "initializemutationr": 8, "initializetreeseq": 8, "initializerecombinationr": 8, "40457e": 8, "tick": 8, "sim": 8, "addsubpop": 8, "6521": 8, "p0": 8, "setsubpopulations": 8, "8521": 8, "8721": 8, "sampleindividu": 8, "treeseqrememberindividu": 8, "wonder": 8, "obvious": 8, "wrong": 8, "resembl": 8, "nearli": 8, "complex": 8, "mostli": 8, "ones": 8, "num_popul": 8, "notebook": 8, "schemat": 8, "chosen": 8, "demesdraw": 8, "size_histori": 8, "tube": 8, "visual": 8, "to_dem": 8, "lower": 8, "ingredi": 8, "num_sit": 8, "152582": 8, "152": 8, "582": 8, "variant": 8, "got": 8, "num_sampl": 8, "enumer": 8, "len": 8, "predefin": 8, "mind": 8, "sequence_length": 8, "2820402396300886e": 8, "crazi": 8, "num_mut": 8, "1322": 8, "num_tre": 8, "1mb": 8, "notic": 8, "write_vcf": 8, "vcf_file": 8, "contig_id": 8, "fileformat": 8, "vcfv4": 8, "filter": 8, "gt": 8, "chrom": 8, "po": 8, "alt": 8, "qual": 8, "tsk_0": 8, "tsk_1": 8, "tsk_2": 8, "tsk_3": 8, "tsk_4": 8, "511": 8, "1209": 8, "1308": 8, "2271": 8, "2637": 8, "3615": 8, "4391": 8, "fact": 8, "pyslim": 8, "extract": 8, "exchang": 8, "10e6": 8, "20e6": 8, "isn": 8, "besid": 8, "fairli": 8, "print_histori": 8, "demographydebugg": 8, "growth_rat": 8, "432124": 8, "14474": 8, "initial_s": 8, "92e": 8, "5920": 8, "7310": 8, "longest": 8, "731": 8, "contextlib": 8, "redirect_stdout": 8, "trees_fil": 8, "temporari": 8, "defineconst": 8, "tmp": 8, "tmp4hyf8ugn": 8, "gui": 8, "investig": 8, "rout": 8, "postprocess": 8, "happili": 8, "dump": 8, "foo_recap": 8, "crucial": 8, "simplifi": 8, "whose": 8, "extran": 8, "extra": 8, "wast": 8, "slowli": 8, "real": 8, "suitabl": 8, "nonsynonym": 8, "selection_coeff_from_mut": 8, "num_neutr": 8, "nonneutr": 8, "167": 8, "10kb": 8, "flank": 8, "middl": 8, "imagin": 8, "concret": 8, "30000": 8, "gene_interv": 8, "20000": 8, "flatten": 8, "append": 8, "coeff": 8, "3000": 8, "aren": 8, "30e6": 8, "exon_interv": 8, "magnitud": 8, "span_normalis": 8, "pi": 8, "3f": 8, "215": 8, "380": 8, "except": 8, "locus_id": 8, "round": 8, "overwritten": 8, "strongli": 8, "imposs": 8, "comparison": 8, "ts_neutral": 8, "lastli": 8, "side": 8, "despit": 8, "applic": 8, "unscal": 8, "matplotlib": 8, "pyplot": 8, "plt": 8, "neutral_pi": 8, "sweep_pi": 8, "axvlin": 8, "color": 8, "black": 8, "linestyl": 8, "dash": 8, "legend": 8, "xlabel": 8, "ylabel": 8, "vertic": 8, "certainli": 8, "dive": 8, "yourself": 8, "borrow": 8, "arguabl": 8, "biolog": 8, "swath": 8, "breakag": 8, "cellular": 8, "machineri": 8, "varieti": 8, "catalogu": 8, "100kb": 8, "vaquita": 8, "1e5": 8, "mayb": 8, "sites_posit": 8, "10000142": 8, "19999926": 8, "preserv": 8, "10mb": 8, "20mb": 8, "misss": 8, "encod": 8, "surpris": 8, "num_root": 8, "root_threshold": 8, "correctli": 8, "america": 8, "number_sampl": 8, "sampling_time_gener": 8, "1523470111585671e": 8, "took": 8, "laptop": 8, "consol": 8, "denot": 8, "d_": 8, "xy": 8, "quantiti": 8, "sample_set": 8, "sample_list": 8, "tolist": 8, "simpler": 8, "div": 8, "00078192": 8, "00080099": 8, "00080262": 8, "00079789": 8, "00056527": 8, "00063978": 8, "00063219": 8, "00057068": 8, "00062214": 8, "00064897": 8, "n_e": 8, "000472": 8, "nicer": 8, "heatmap": 8, "seaborn": 8, "div_matrix": 8, "pop0": 8, "pop1": 8, "vmin": 8, "squar": 8, "fontweight": 8, "bold": 8, "xtick": 8, "asi": 8, "adm": 8, "ytick": 8, "highest": 8, "lowest": 8, "themselv": 8, "overwhelm": 8, "evid": 8, "5000": 8, "4000": 8, "pop2": 8, "summaris": 8, "allele_frequency_spectrum": 8, "pop_sampl": 8, "dtype": 8, "int32": 8, "polymorph": 8, "polaris": 8, "sfs0": 8, "1686": 8, "2496": 8, "1232": 8, "614": 8, "566": 8, "456": 8, "396": 8, "309": 8, "singleton": 8, "sfs1": 8, "3790": 8, "729": 8, "583": 8, "522": 8, "386": 8, "285": 8, "264": 8, "680": 8, "mysteri": 8, "fold": 8, "9050": 8, "bar_width": 8, "r1": 8, "arang": 8, "r2": 8, "bar": 8, "height": 8, "width": 8, "notabl": 8, "absent": 8}, "objects": {"stdpopsim": [[0, 0, 1, "", "Annotation"], [0, 0, 1, "", "Chromosome"], [0, 0, 1, "", "Citation"], [0, 0, 1, "", "Contig"], [0, 0, 1, "", "DFE"], [0, 0, 1, "", "DemographicModel"], [0, 0, 1, "", "Engine"], [0, 0, 1, "", "Genome"], [0, 0, 1, "", "IsolationWithMigration"], [0, 0, 1, "", "MutationType"], [0, 0, 1, "", "PiecewiseConstantSize"], [0, 0, 1, "", "Population"], [0, 0, 1, "", "Species"], [0, 4, 1, "", "get_default_engine"], [0, 4, 1, "", "get_engine"], [0, 4, 1, "", "get_species"], [0, 4, 1, "", "register_engine"], [0, 4, 1, "", "selective_sweep"]], "stdpopsim.Annotation": [[0, 1, 1, "", "download"], [0, 1, 1, "", "get_chromosome_annotations"], [0, 1, 1, "", "is_cached"]], "stdpopsim.Citation": [[0, 1, 1, "", "assert_valid"], [0, 1, 1, "", "because"], [0, 1, 1, "", "fetch_bibtex"], [0, 1, 1, "", "merge"]], "stdpopsim.Contig": [[0, 1, 1, "", "add_dfe"], [0, 1, 1, "", "add_single_site"], [0, 1, 1, "", "clear_dfes"], [0, 1, 1, "", "dfe_breakpoints"], [0, 2, 1, "", "is_neutral"], [0, 1, 1, "", "mutation_types"], [0, 2, 1, "", "origin"], [0, 1, 1, "", "species_contig"]], "stdpopsim.DFE": [[0, 1, 1, "", "register_qc"]], "stdpopsim.DemographicModel": [[0, 1, 1, "", "get_sample_sets"], [0, 1, 1, "", "get_samples"], [0, 1, 1, "", "register_qc"]], "stdpopsim.Engine": [[0, 1, 1, "", "get_version"], [0, 1, 1, "", "simulate"]], "stdpopsim.Genome": [[0, 1, 1, "", "from_data"], [0, 1, 1, "", "get_chromosome"], [0, 2, 1, "", "mean_gene_conversion_fraction"], [0, 2, 1, "", "mean_mutation_rate"], [0, 2, 1, "", "mean_recombination_rate"], [0, 2, 1, "", "range_gene_conversion_lengths"]], "stdpopsim.MutationType": [[0, 2, 1, "", "is_neutral"]], "stdpopsim.Population": [[0, 1, 1, "", "asdict"]], "stdpopsim.Species": [[0, 1, 1, "", "get_annotations"], [0, 1, 1, "", "get_contig"], [0, 1, 1, "", "get_demographic_model"], [0, 1, 1, "", "get_dfe"]], "stdpopsim.engines": [[0, 0, 1, "", "_MsprimeEngine"]], "stdpopsim.engines._MsprimeEngine": [[0, 3, 1, "", "description"], [0, 3, 1, "", "id"], [0, 1, 1, "", "simulate"]], "stdpopsim.slim_engine": [[0, 0, 1, "", "_SLiMEngine"]], "stdpopsim.slim_engine._SLiMEngine": [[0, 3, 1, "", "description"], [0, 3, 1, "", "id"], [0, 1, 1, "", "recap_and_rescale"], [0, 1, 1, "", "simulate"]]}, "objtypes": {"0": "py:class", "1": "py:method", "2": "py:property", "3": "py:attribute", "4": "py:function"}, "objnames": {"0": ["py", "class", "Python class"], "1": ["py", "method", "Python method"], "2": ["py", "property", "Python property"], "3": ["py", "attribute", "Python attribute"], "4": ["py", "function", "Python function"]}, "titleterms": {"api": [0, 1, 8], "quick": [0, 6], "refer": 0, "speci": [0, 4, 8], "definit": 0, "demograph": [0, 1, 4, 8], "model": [0, 1, 4, 8], "gene": [0, 8], "convers": 0, "bacteri": 0, "recombin": [0, 4], "select": [0, 8], "dfe": [0, 1, 4, 8], "sweep": [0, 8], "gener": [0, 1, 8], "simul": [0, 8], "engin": [0, 8], "catalog": 1, "aed": 1, "aegypti": 1, "genom": [1, 8], "ana": 1, "platyrhyncho": 1, "north": 1, "american": 1, "mallard": 1, "black": 1, "duck": 1, "split": 1, "anoli": 1, "carolinensi": 1, "anophel": 1, "gambia": 1, "stairwayplot": 1, "estim": 1, "n": 1, "t": 1, "gabon": 1, "sampl": [1, 8], "mellifera": 1, "arabidopsi": 1, "thaliana": 1, "genet": [1, 3, 4, 8], "map": [1, 3, 4, 8], "salomeaveraged_tair10": 1, "south": 1, "middl": 1, "atla": 1, "piecewis": 1, "constant": 1, "size": 1, "african": 1, "two": 1, "epoch": 1, "three": 1, "annot": [1, 4], "araport_11_exon": 1, "araport_11_cd": 1, "distribut": 1, "fit": 1, "effect": 1, "gamma_h18": 1, "bo": 1, "tauru": 1, "holstein": 1, "friesian": 1, "cattl": 1, "macleod": 1, "et": 1, "al": 1, "2013": 1, "boitard": 1, "2016": 1, "fleckvieh": 1, "jersei": 1, "angu": 1, "caenorhabd": 1, "elegan": 1, "rockmanriail_ce11": 1, "cani": 1, "familiari": 1, "campbell2016_canfam3_1": 1, "chlamydomona": 1, "reinhardtii": 1, "drosophila": [1, 8], "melanogast": [1, 8], "comeroncrossover_dm6": 1, "comeroncrossoverv2_dm6": 1, "popul": 1, "european": 1, "flybase_bdgp6": 1, "32": 1, "51_exon": 1, "51_cd": 1, "gamma_h17": 1, "lognormalpluspositive_r16": 1, "sechellia": 1, "escherichia": 1, "coli": 1, "gasterosteu": 1, "aculeatu": 1, "helianthu": 1, "annuu": 1, "heliconiu": 1, "melpomen": 1, "homo": 1, "sapien": 1, "hapmapii_grch37": 1, "hapmapii_grch38": 1, "decodesexaveraged_grch36": 1, "decodesexaveraged_grch38": 1, "pyrhoacb_grch38": 1, "pyrhoasw_grch38": 1, "pyrhobeb_grch38": 1, "pyrhocdx_grch38": 1, "pyrhoceu_grch38": 1, "pyrhochb_grch38": 1, "pyrhochs_grch38": 1, "pyrhoclm_grch38": 1, "pyrhoesn_grch38": 1, "pyrhofin_grch38": 1, "pyrhogbr_grch38": 1, "pyrhogih_grch38": 1, "pyrhogwd_grch38": 1, "pyrhoibs_grch38": 1, "pyrhoitu_grch38": 1, "pyrhojpt_grch38": 1, "pyrhokhv_grch38": 1, "pyrholwk_grch38": 1, "pyrhomsl_grch38": 1, "pyrhomxl_grch38": 1, "pyrhopel_grch38": 1, "pyrhopjl_grch38": 1, "pyrhopur_grch38": 1, "pyrhostu_grch38": 1, "pyrhotsi_grch38": 1, "pyrhoyri_grch38": 1, "out": 1, "africa": 1, "an": [1, 8], "extend": 1, "puls": 1, "neandert": 1, "admixtur": 1, "archaic": 1, "period": 1, "growth": 1, "declin": 1, "multi": 1, "ancient": 1, "eurasia": 1, "papuan": 1, "ashkenazi": 1, "jewish": 1, "substructur": 1, "4": [1, 8], "europ": 1, "ensembl_havana_104_exon": 1, "ensembl_havana_104_cd": 1, "gamma_k17": 1, "lognormal_h17": 1, "mixed_k23": 1, "mu": 1, "musculu": 1, "m": 1, "domesticu": 1, "oryza": 1, "sativa": 1, "bottleneck": 1, "migrat": 1, "origin": 1, "domest": 1, "rice": 1, "varieti": 1, "pan": 1, "troglodyt": 1, "ghost": 1, "bonobo": 1, "papio": 1, "anubi": 1, "pyrho_panubis1_0": 1, "smc": 1, "individu": 1, "phocoena": 1, "sinu": 1, "vaquita": 1, "phocoena_sinu": 1, "mphosin1": 1, "pri": 1, "110_exon": 1, "110_cd": 1, "gamma_r22": 1, "pongo": 1, "abelii": 1, "naterpa_ponabe3": 1, "naterpp_ponabe3": 1, "orangutan": 1, "streptococcu": 1, "agalactia": 1, "changelog": 2, "0": 2, "2": [2, 8], "1a": 2, "2024": 2, "07": 2, "06": 2, "2022": 2, "11": 2, "01": 2, "1": [2, 8], "2020": 2, "05": 2, "29": 2, "02": 2, "2019": 2, "12": 2, "18": 2, "command": [3, 8], "line": [3, 8], "option": [3, 8], "posit": 3, "argument": 3, "name": [3, 4], "msprime": 3, "specif": 3, "paramet": [3, 4], "slim": [3, 8], "sub": 3, "aedaeg": 3, "anapla": 3, "anocar": 3, "anogam": 3, "apimel": 3, "aratha": 3, "bostau": 3, "caeel": 3, "canfam": 3, "chlrei": 3, "dromel": 3, "drosec": 3, "esccol": 3, "gasacu": 3, "helann": 3, "helmel": 3, "homsap": 3, "musmu": 3, "orysat": 3, "pantro": 3, "papanu": 3, "phosin": 3, "ponab": 3, "straga": 3, "download": 3, "develop": 4, "instal": [4, 6], "us": [4, 8], "virtual": 4, "environ": 4, "github": 4, "workflow": 4, "pre": 4, "commit": 4, "check": [4, 8], "rebas": 4, "when": 4, "goe": 4, "wrong": 4, "ad": 4, "new": 4, "which": 4, "inform": 4, "do": 4, "i": 4, "need": 4, "have": 4, "my": 4, "get": [4, 7], "set": [4, 8], "up": [4, 8], "add": 4, "code": 4, "test": 4, "your": 4, "submit": 4, "pr": 4, "overview": 4, "stdpopsim": [4, 5, 8], "review": 4, "process": 4, "implement": 4, "what": 4, "ar": 4, "appropri": 4, "tabl": [4, 5], "doc": 4, "lift": 4, "over": 4, "standard": 4, "convent": 4, "unit": 4, "coverag": 4, "document": [4, 5], "make": 4, "releas": 4, "welcom": 5, "s": 5, "content": 5, "indic": 5, "requir": 6, "conda": 6, "start": 6, "pip": 6, "run": [6, 8], "cli": [6, 8], "introduct": 7, "first": [7, 8], "step": 7, "involv": 7, "citat": 7, "licenc": 7, "usag": 7, "tutori": 8, "interfac": 8, "A": 8, "choos": 8, "contig": 8, "scheme": 8, "convert": 8, "output": 8, "vcf": 8, "specifi": 8, "scale": 8, "factor": 8, "debug": 8, "from": 8, "python": 8, "publish": 8, "pick": 8, "saniti": 8, "tree": 8, "sequenc": 8, "exampl": 8, "other": 8, "The": 8, "burn": 8, "script": 8, "incorpor": 8, "wide": 8, "singl": 8, "3": 8, "exon": 8, "5": 8, "one": 8, "anoth": 8, "tip": 8, "trick": 8, "gotcha": 8, "miss": 8, "data": 8, "coordin": 8, "analys": 8, "calcul": 8, "diverg": 8, "dataset": 8, "plot": 8, "allel": 8, "frequenc": 8, "spectrum": 8, "af": 8}, "envversion": {"sphinx.domains.c": 2, "sphinx.domains.changeset": 1, "sphinx.domains.citation": 1, "sphinx.domains.cpp": 6, "sphinx.domains.index": 1, "sphinx.domains.javascript": 2, "sphinx.domains.math": 2, "sphinx.domains.python": 3, "sphinx.domains.rst": 2, "sphinx.domains.std": 2, "sphinx.ext.intersphinx": 1, "sphinx.ext.todo": 2, "sphinx.ext.viewcode": 1, "sphinx": 56}})
\ No newline at end of file
diff --git a/main/tutorial.html b/main/tutorial.html
index 4682e3d..3047895 100644
--- a/main/tutorial.html
+++ b/main/tutorial.html
@@ -324,7 +324,7 @@ Choose a model and a sampling scheme# OutOfAfrica_3G09
# OutOfAfrica_2T12
# Africa_1T12
-# AmericanAdmixture_4B11
+# AmericanAdmixture_4B18
# OutOfAfricaArchaicAdmixture_5R19
# Zigzag_1S14
# AncientEurasia_9K19
@@ -1602,8 +1602,8 @@ 1. Simulating the datasetBrowning et al. (2018).
-From the help output (or the Catalog),
-we can see that this model has id AmericanAdmixture_4B11
,
+From the help output (or the Catalog),
+we can see that this model has id AmericanAdmixture_4B18
,
and allows samples to be drawn from 4 contemporary populations representing African,
European, Asian and African-American groups.
Using the --help-genetic-maps
option, we can also see what genetic maps
@@ -1640,10 +1640,10 @@
1. Simulating the dataset-D option.
This will print information about the simulation to the terminal:
-$ stdpopsim HomSap -c chr1 -o afr-america-chr1.trees -s 13 -g HapMapII_GRCh38 -d AmericanAdmixture_4B11 AFR:2 EUR:2 ASIA:2 ADMIX:2 -D
+$ stdpopsim HomSap -c chr1 -o afr-america-chr1.trees -s 13 -g HapMapII_GRCh38 -d AmericanAdmixture_4B18 AFR:2 EUR:2 ASIA:2 ADMIX:2 -D
Simulation information:
Engine: msprime (1.3.3)
- Model id: AmericanAdmixture_4B11
+ Model id: AmericanAdmixture_4B18
Model description: American admixture
Seed: 13
Population: number_samples (sampling_time_generations):
@@ -1665,7 +1665,7 @@ 1. Simulating the dataset-D flag to run the simulation
(this took around 8 minutes to run on a laptop).
$ stdpopsim HomSap -c chr1 -o afr-america-chr1.trees -s 13 -g HapMapII_GRCh38 \
-$ -d AmericanAdmixture_4B11 AFR:2 EUR:2 ASIA:2 ADMIX:2
+$ -d AmericanAdmixture_4B18 AFR:2 EUR:2 ASIA:2 ADMIX:2