[NTR] tuft cell of stomach

[Caroline-99]

Please check that the term does not already exist by using the ontology search tool OLS:
https://www.ebi.ac.uk/ols4/ontologies/cl

Preferred term label
tuft cell of stomach

Synonyms (add reference(s), please)
gastric tuft cell - exact synonym

Definition (free text, with reference(s), please. PubMed ID format is PMID:XXXXXX)

A tuft cell that is part of the epithelium of the stomach. This cell is characterized by gastric chemosensation and immune regulation through IL-25 secretion, which activates ILC2s to produce IL-13, driving epithelial remodelling and tuft cell expansion. Unlike intestinal tuft cells, which are primarily involved in helminth defense and type 2 immunity, the tuft cell of the stomach is primarily involved in inflammation, metaplasia, and hyperplasia.

doi:/10.1101/2022.02.16.480779
PMID: 22527717
PMID: 38117182

Parent cell type term (check the hierarchy here https://www.ebi.ac.uk/ols4/ontologies/cl)
brush cell

Anatomical structure where the cell type is found (check Uberon for anatomical structures: https://www.ebi.ac.uk/ols4/ontologies/uberon)
epithelium of the stomach

Your ORCID

Additional notes or concerns