diff --git a/doc/FAQ.md b/doc/FAQ.md index 8abab76..783cdbc 100644 --- a/doc/FAQ.md +++ b/doc/FAQ.md @@ -3,7 +3,7 @@ ### Can I use HiC-Pro with the Arima Hi-C Kit ? Yes, the LIGATION_SITE variable from the configuration file can contain multiple ligation motifs (comma separated). -Regarding the Arima kit, as there is two restiction motifs (GATC and GANT), the possible ligation motifs should be GATCGATC, GATCGANT, GANTGATC, GANTGANT. +Regarding the Arima kit, as there is two restiction motifs (^GATC and G^ANTC), the possible ligation motifs should be GATCGATC,GANTGATC,GANTANTC,GATCANTC. Leading to 25 possible ligation motifs when the 'N' are replaced by 'A', 'C', 'G', 'T'. Since HiC-Pro version 2.11.3, 'N' base are automatically recognized. For older version, please specify all possible ligation motifs.