diff --git a/Resources/Prototypes/Entities/Mobs/NPCs/argocyte.yml b/Resources/Prototypes/Entities/Mobs/NPCs/argocyte.yml
index 39e68b63a78..c9fcf9b01d8 100644
--- a/Resources/Prototypes/Entities/Mobs/NPCs/argocyte.yml
+++ b/Resources/Prototypes/Entities/Mobs/NPCs/argocyte.yml
@@ -51,6 +51,8 @@
   - type: Flashable
   - type: NameIdentifier
     group: GenericNumber
+  - type: TimedDespawn # Frontier
+    lifetime: 3000 # Frontier: 50 mins (max blue space event duration involving these mobs - 40 mins)
 
 - type: entity
   parent: BaseMobArgocyte
diff --git a/Resources/Prototypes/Entities/Mobs/NPCs/carp.yml b/Resources/Prototypes/Entities/Mobs/NPCs/carp.yml
index 6f4d3512b6e..4e39fafcdb8 100644
--- a/Resources/Prototypes/Entities/Mobs/NPCs/carp.yml
+++ b/Resources/Prototypes/Entities/Mobs/NPCs/carp.yml
@@ -79,6 +79,8 @@
       interactFailureString: petting-failure-carp
       interactFailureSound:
         path: /Audio/Effects/bite.ogg
+    - type: TimedDespawn # Frontier
+      lifetime: 10800 # Frontier: 3 hours (I believe asteroids and wrecks despawn after 3 hours hence the value)
 
 - type: entity
   parent: BaseMobCarp
diff --git a/Resources/Prototypes/Entities/Mobs/NPCs/space.yml b/Resources/Prototypes/Entities/Mobs/NPCs/space.yml
index c15458ff394..13041865fe4 100644
--- a/Resources/Prototypes/Entities/Mobs/NPCs/space.yml
+++ b/Resources/Prototypes/Entities/Mobs/NPCs/space.yml
@@ -67,6 +67,8 @@
   - type: GhostTakeoverAvailable
   - type: Speech
     speechVerb: LargeMob
+  - type: TimedDespawn # Frontier
+    lifetime: 10800 # Frontier: 3 hours (I believe asteroids and wrecks despawn after 3 hours hence the value)
 
 - type: entity
   name: space bear
diff --git a/Resources/Prototypes/Entities/Mobs/NPCs/spacetick.yml b/Resources/Prototypes/Entities/Mobs/NPCs/spacetick.yml
index 0a2b4f80bbc..2af33d60c66 100644
--- a/Resources/Prototypes/Entities/Mobs/NPCs/spacetick.yml
+++ b/Resources/Prototypes/Entities/Mobs/NPCs/spacetick.yml
@@ -79,6 +79,8 @@
   - type: Speech
     speechVerb: SmallMob
   - type: NonSpreaderZombie
+  - type: TimedDespawn # Frontier
+    lifetime: 10800 # Frontier: 3 hours (I believe asteroids and wrecks despawn after 3 hours hence the value)
 
 - type: entity
   id: MobTickSalvage
diff --git a/Resources/Prototypes/_NF/Entities/Mobs/NPCs/arcadiaindustries.yml b/Resources/Prototypes/_NF/Entities/Mobs/NPCs/arcadiaindustries.yml
index 8d8308419e4..2c9ad9b720e 100644
--- a/Resources/Prototypes/_NF/Entities/Mobs/NPCs/arcadiaindustries.yml
+++ b/Resources/Prototypes/_NF/Entities/Mobs/NPCs/arcadiaindustries.yml
@@ -68,6 +68,8 @@
         types:
           Bloodloss:
             1
+    - type: TimedDespawn
+      lifetime: 1800 # 30 mins (max blue space event duration involving these mobs - 20 mins)
 
 - type: entity
   name: Hijacked Hologuardian
@@ -123,6 +125,8 @@
         types:
           Bloodloss:
             1
+    - type: TimedDespawn
+      lifetime: 1800 # 30 mins (max blue space event duration involving these mobs - 20 mins)
 
 - type: entity
   name: Mobile Blaster Unit
@@ -194,3 +198,5 @@
         types:
           Bloodloss:
             1
+    - type: TimedDespawn
+      lifetime: 1800 # 30 mins (max blue space event duration involving these mobs - 20 mins)
diff --git a/Resources/Prototypes/_NF/Entities/Mobs/NPCs/bloodcultistmob.yml b/Resources/Prototypes/_NF/Entities/Mobs/NPCs/bloodcultistmob.yml
index 810ea1fba6a..4735bad2085 100644
--- a/Resources/Prototypes/_NF/Entities/Mobs/NPCs/bloodcultistmob.yml
+++ b/Resources/Prototypes/_NF/Entities/Mobs/NPCs/bloodcultistmob.yml
@@ -18,6 +18,8 @@
     NextAdvertisementTime: 10
   - type: AutoWakeUp
   - type: MovementAlwaysTouching
+  - type: TimedDespawn
+    lifetime: 3000 # 50 mins (max blue space event duration involving these mobs - 40 mins)
 
 # Humans
 # Blood Cult Priest, ranged mab, bolts deal 10 slash damage
diff --git a/Resources/Prototypes/_NF/Entities/Mobs/NPCs/syndicatemob.yml b/Resources/Prototypes/_NF/Entities/Mobs/NPCs/syndicatemob.yml
index 3ec108980f1..9dce13e6c9b 100644
--- a/Resources/Prototypes/_NF/Entities/Mobs/NPCs/syndicatemob.yml
+++ b/Resources/Prototypes/_NF/Entities/Mobs/NPCs/syndicatemob.yml
@@ -29,6 +29,8 @@
   - type: Buckle
     disable: true
   - type: AutoWakeUp
+  - type: TimedDespawn
+    lifetime: 3000 # 50 mins (max blue space event duration involving these mobs - 40 mins)
 
 # Humans
 # Syndicate Captain, "armed" with AP Python
diff --git a/Resources/Prototypes/_NF/Entities/Mobs/NPCs/wizardfederationmob.yml b/Resources/Prototypes/_NF/Entities/Mobs/NPCs/wizardfederationmob.yml
index 87c8f17e244..80244f6371a 100644
--- a/Resources/Prototypes/_NF/Entities/Mobs/NPCs/wizardfederationmob.yml
+++ b/Resources/Prototypes/_NF/Entities/Mobs/NPCs/wizardfederationmob.yml
@@ -40,6 +40,8 @@
     NextAdvertisementTime: 10
   - type: AutoWakeUp
   - type: MovementAlwaysTouching
+  - type: TimedDespawn
+    lifetime: 1800 # 30 mins (max blue space event duration involving these mobs - 20 mins)
 
 # Humans
 # Blue Wizard, summons 2 Blue Curacao Elementals