From 0eec1c8c6b2b8372cfe834489d62c78a7edb50fd Mon Sep 17 00:00:00 2001 From: Vincent Rubinetti Date: Fri, 3 Nov 2023 17:58:10 -0400 Subject: [PATCH 1/8] convert phenogrid to svg --- frontend/README.md | 9 +- frontend/e2e/axe.test.ts | 3 +- frontend/fixtures/association-counts.json | 19 - frontend/fixtures/entity.json | 14 - frontend/fixtures/node.json | 88 +- .../fixtures/phenotype-explorer-compare.json | 4285 ++++++++++++++++- frontend/package.json | 1 - frontend/src/api/index.ts | 5 +- frontend/src/api/model.ts | 47 +- frontend/src/components/AppDetail.vue | 2 +- frontend/src/components/AppModal.vue | 6 +- frontend/src/components/AppPlaceholder.vue | 7 +- frontend/src/components/AppSelectMulti.vue | 2 +- frontend/src/components/AppSelectSingle.vue | 2 +- frontend/src/components/AppTabs.vue | 2 +- frontend/src/components/TheFloatButtons.vue | 4 +- frontend/src/components/ThePhenogrid.vue | 676 +-- .../src/components/TheTableOfContents.vue | 8 +- frontend/src/global/components.ts | 3 - frontend/src/global/styles.scss | 13 +- frontend/src/global/tooltip.ts | 11 +- frontend/src/global/variables.scss | 5 +- frontend/src/pages/PageTestbed.vue | 4 +- .../src/pages/about/PagePhenomicsFirst.vue | 42 +- frontend/src/pages/about/PagePublications.vue | 3 - frontend/src/pages/explore/PagePhenogrid.vue | 24 +- .../pages/explore/TabPhenotypeExplorer.vue | 54 +- frontend/src/pages/explore/TabSearch.vue | 4 +- frontend/src/pages/metadata.json | 12 +- .../pages/node/SectionAssociationDetails.vue | 51 +- frontend/src/router/index.ts | 57 +- frontend/src/util/dom.ts | 56 +- frontend/src/util/download.ts | 45 +- frontend/yarn.lock | 35 +- 34 files changed, 4916 insertions(+), 683 deletions(-) delete mode 100644 frontend/fixtures/association-counts.json delete mode 100644 frontend/fixtures/entity.json diff --git a/frontend/README.md b/frontend/README.md index b80a88684..e8292fb69 100644 --- a/frontend/README.md +++ b/frontend/README.md @@ -120,14 +120,9 @@ Useful for setting the dimensions of your iframe container, for example: ```js window.addEventListener("message", (event) => { - // get your iframe dom element somehow const iframe = document.querySelector("iframe"); - // some static styles that should probably be on it to prevent overflow - iframe.style.maxWidth = "100%"; - iframe.style.maxHeight = "100%"; - // dynamically fit dimensions to content (with some padding for possible scroll bars) - iframe.style.width = event.data.width + 20 + "px"; - iframe.style.height = event.data.height + 20 + "px"; + iframe.style.maxWidth = event.data.width + "px"; + iframe.style.maxHeight = event.data.height + "px"; }); ``` diff --git a/frontend/e2e/axe.test.ts b/frontend/e2e/axe.test.ts index 5563b344d..f398aecf1 100644 --- a/frontend/e2e/axe.test.ts +++ b/frontend/e2e/axe.test.ts @@ -10,7 +10,6 @@ const paths = [ "/explore", "/about", "/help", - "/overview", "/cite", "/team", "/publications", @@ -33,6 +32,8 @@ const rules = [ { id: "color-contrast", enabled: false }, /** ignore select dropdowns that are appended to body */ { id: "region", selector: ":not([role='listbox']" }, + /** ignore iframes */ + { id: "page-has-heading-one", selector: ":not(iframe)" }, ]; type Test = Parameters[1]; diff --git a/frontend/fixtures/association-counts.json b/frontend/fixtures/association-counts.json deleted file mode 100644 index 207c58a9c..000000000 --- a/frontend/fixtures/association-counts.json +++ /dev/null @@ -1,19 +0,0 @@ -{ - "items": [ - { - "label": "Phenotypes", - "count": 4027, - "category": "biolink:DiseaseToPhenotypicFeatureAssociation" - }, - { - "label": "Causal Genes", - "count": 124, - "category": "biolink:CausalGeneToDiseaseAssociation" - }, - { - "label": "Correlated Genes", - "count": 151, - "category": "biolink:CorrelatedGeneToDiseaseAssociation" - } - ] -} diff --git a/frontend/fixtures/entity.json b/frontend/fixtures/entity.json deleted file mode 100644 index 766f989c9..000000000 --- a/frontend/fixtures/entity.json +++ /dev/null @@ -1,14 +0,0 @@ -{ - "id": "MONDO:0020121", - "category": "biolink:Disease", - "name": "muscular dystrophy", - "full_name": null, - "description": "Muscular dystrophy (MD) refers to a group of more than 30 genetic diseases characterized by progressive weakness and degeneration of the skeletal muscles that control movement. Some forms of MD are seen in newborns, infants or children, while others have late-onset and may not appear until middle age or later. The disorders differ in terms of the distribution and extent of muscle weakness (some forms of MD also affect cardiac muscle), age of onset, rate of progression, and pattern of inheritance. The prognosis for people with MD varies according to the type and progression of the disorder. There is no specific treatment to stop or reverse any form of MD. Treatment is supportive and may include physical therapy, respiratory therapy, speech therapy, orthopedic appliances used for support, corrective orthopedic surgery, and medicationsincluding corticosteroids, anticonvulsants (seizure medications), immunosuppressants, and antibiotics. Some individuals may need assisted ventilation to treat respiratory muscle weaknessor a pacemaker for cardiac (heart)abnormalities.", - "xref": [], - "provided_by": "phenio_nodes", - "in_taxon": null, - "in_taxon_label": null, - "symbol": null, - "synonym": [], - "uri": "http://purl.obolibrary.org/obo/MONDO_0020121" -} diff --git a/frontend/fixtures/node.json b/frontend/fixtures/node.json index baf9051e2..70b327106 100644 --- a/frontend/fixtures/node.json +++ b/frontend/fixtures/node.json @@ -10,7 +10,6 @@ "in_taxon_label": null, "symbol": null, "synonym": [], - "uri": null, "inheritance": null, "causal_gene": [], "causes_disease": [], @@ -39,9 +38,9 @@ "node_hierarchy": { "super_classes": [ { - "id": "MONDO:0019056", + "id": "MONDO:0005336", "category": "biolink:Disease", - "name": "neuromuscular disease", + "name": "myopathy", "full_name": null, "description": null, "xref": [], @@ -49,8 +48,7 @@ "in_taxon": null, "in_taxon_label": null, "symbol": null, - "synonym": [], - "uri": null + "synonym": [] }, { "id": "MONDO:0700223", @@ -63,13 +61,12 @@ "in_taxon": null, "in_taxon_label": null, "symbol": null, - "synonym": [], - "uri": null + "synonym": [] }, { - "id": "MONDO:0005336", + "id": "MONDO:0019056", "category": "biolink:Disease", - "name": "myopathy", + "name": "neuromuscular disease", "full_name": null, "description": null, "xref": [], @@ -77,15 +74,14 @@ "in_taxon": null, "in_taxon_label": null, "symbol": null, - "synonym": [], - "uri": null + "synonym": [] } ], "sub_classes": [ { - "id": "MONDO:0018949", + "id": "MONDO:0008028", "category": "biolink:Disease", - "name": "distal myopathy", + "name": "muscular dystrophy, Barnes type", "full_name": null, "description": null, "xref": [], @@ -93,13 +89,12 @@ "in_taxon": null, "in_taxon_label": null, "symbol": null, - "synonym": [], - "uri": null + "synonym": [] }, { - "id": "MONDO:0019950", + "id": "MONDO:0010675", "category": "biolink:Disease", - "name": "congenital muscular dystrophy", + "name": "muscular dystrophy, cardiac type", "full_name": null, "description": null, "xref": [], @@ -107,13 +102,12 @@ "in_taxon": null, "in_taxon_label": null, "symbol": null, - "synonym": [], - "uri": null + "synonym": [] }, { - "id": "MONDO:0023204", + "id": "MONDO:0010676", "category": "biolink:Disease", - "name": "Fukuda-Miyanomae-Nakata syndrome", + "name": "muscular dystrophy, Hemizygous lethal type", "full_name": null, "description": null, "xref": [], @@ -121,13 +115,12 @@ "in_taxon": null, "in_taxon_label": null, "symbol": null, - "synonym": [], - "uri": null + "synonym": [] }, { - "id": "MONDO:0100228", + "id": "MONDO:0010677", "category": "biolink:Disease", - "name": "LAMA2-related muscular dystrophy", + "name": "muscular dystrophy, Mabry type", "full_name": null, "description": null, "xref": [], @@ -135,13 +128,12 @@ "in_taxon": null, "in_taxon_label": null, "symbol": null, - "synonym": [], - "uri": null + "synonym": [] }, { - "id": "MONDO:0008028", + "id": "MONDO:0010678", "category": "biolink:Disease", - "name": "muscular dystrophy, Barnes type", + "name": "muscular dystrophy, progressive Pectorodorsal", "full_name": null, "description": null, "xref": [], @@ -149,13 +141,12 @@ "in_taxon": null, "in_taxon_label": null, "symbol": null, - "synonym": [], - "uri": null + "synonym": [] }, { - "id": "MONDO:0010675", + "id": "MONDO:0016106", "category": "biolink:Disease", - "name": "muscular dystrophy, cardiac type", + "name": "progressive muscular dystrophy", "full_name": null, "description": null, "xref": [], @@ -163,13 +154,12 @@ "in_taxon": null, "in_taxon_label": null, "symbol": null, - "synonym": [], - "uri": null + "synonym": [] }, { - "id": "MONDO:0010676", + "id": "MONDO:0018949", "category": "biolink:Disease", - "name": "muscular dystrophy, Hemizygous lethal type", + "name": "distal myopathy", "full_name": null, "description": null, "xref": [], @@ -177,13 +167,12 @@ "in_taxon": null, "in_taxon_label": null, "symbol": null, - "synonym": [], - "uri": null + "synonym": [] }, { - "id": "MONDO:0010677", + "id": "MONDO:0019950", "category": "biolink:Disease", - "name": "muscular dystrophy, Mabry type", + "name": "congenital muscular dystrophy", "full_name": null, "description": null, "xref": [], @@ -191,13 +180,12 @@ "in_taxon": null, "in_taxon_label": null, "symbol": null, - "synonym": [], - "uri": null + "synonym": [] }, { - "id": "MONDO:0010678", + "id": "MONDO:0023204", "category": "biolink:Disease", - "name": "muscular dystrophy, progressive Pectorodorsal", + "name": "Fukuda-Miyanomae-Nakata syndrome", "full_name": null, "description": null, "xref": [], @@ -205,13 +193,12 @@ "in_taxon": null, "in_taxon_label": null, "symbol": null, - "synonym": [], - "uri": null + "synonym": [] }, { - "id": "MONDO:0016106", + "id": "MONDO:0100228", "category": "biolink:Disease", - "name": "progressive muscular dystrophy", + "name": "LAMA2-related muscular dystrophy", "full_name": null, "description": null, "xref": [], @@ -219,8 +206,7 @@ "in_taxon": null, "in_taxon_label": null, "symbol": null, - "synonym": [], - "uri": null + "synonym": [] } ] } diff --git a/frontend/fixtures/phenotype-explorer-compare.json b/frontend/fixtures/phenotype-explorer-compare.json index 47898790d..0002ff6b2 100644 --- a/frontend/fixtures/phenotype-explorer-compare.json +++ b/frontend/fixtures/phenotype-explorer-compare.json @@ -1,106 +1,4291 @@ { "subject_termset": { - "MP:0002169": { - "id": "MP:0002169", - "label": "no abnormal phenotype detected (MPO)" + "HP:0000869": { + "id": "HP:0000869", + "label": "Secondary amenorrhea (HPO)" }, - "MP:0010771": { - "id": "MP:0010771", - "label": "integument phenotype (MPO)" + "HP:0000135": { + "id": "HP:0000135", + "label": "Hypogonadism (HPO)" + }, + "HP:0007495": { + "id": "HP:0007495", + "label": "Prematurely aged appearance (HPO)" + }, + "HP:0000822": { + "id": "HP:0000822", + "label": "Hypertension (HPO)" + }, + "HP:0010721": { + "id": "HP:0010721", + "label": "Abnormal hair whorl (HPO)" + }, + "HP:0100659": { + "id": "HP:0100659", + "label": "Abnormal cerebral vascular morphology (HPO)" + }, + "HP:0000939": { + "id": "HP:0000939", + "label": "Osteoporosis (HPO)" + }, + "HP:0040217": { + "id": "HP:0040217", + "label": "Elevated hemoglobin A1c (HPO)" + }, + "HP:0100585": { + "id": "HP:0100585", + "label": "Telangiectasia of the skin (HPO)" + }, + "HP:0005328": { + "id": "HP:0005328", + "label": "Progeroid facial appearance (HPO)" + }, + "HP:0002209": { + "id": "HP:0002209", + "label": "Sparse scalp hair (HPO)" + }, + "HP:0004415": { + "id": "HP:0004415", + "label": "Pulmonary artery stenosis (HPO)" + }, + "HP:0000855": { + "id": "HP:0000855", + "label": "Insulin resistance (HPO)" + }, + "HP:0002621": { + "id": "HP:0002621", + "label": "Atherosclerosis (HPO)" + }, + "HP:0002216": { + "id": "HP:0002216", + "label": "Premature graying of hair (HPO)" + }, + "HP:0012056": { + "id": "HP:0012056", + "label": "Cutaneous melanoma (HPO)" + }, + "HP:0002664": { + "id": "HP:0002664", + "label": "Neoplasm (HPO)" + }, + "HP:0000320": { + "id": "HP:0000320", + "label": "Bird-like facies (HPO)" + }, + "HP:0002293": { + "id": "HP:0002293", + "label": "Alopecia of scalp (HPO)" + }, + "HP:0002861": { + "id": "HP:0002861", + "label": "Melanoma (HPO)" + }, + "HP:0009125": { + "id": "HP:0009125", + "label": "Lipodystrophy (HPO)" + }, + "HP:0003002": { + "id": "HP:0003002", + "label": "Breast carcinoma (HPO)" + }, + "HP:0200042": { + "id": "HP:0200042", + "label": "Skin ulcer (HPO)" + }, + "HP:0004349": { + "id": "HP:0004349", + "label": "Reduced bone mineral density (HPO)" + }, + "HP:0001620": { + "id": "HP:0001620", + "label": "High pitched voice (HPO)" + }, + "HP:0002211": { + "id": "HP:0002211", + "label": "White forelock (HPO)" + }, + "HP:0000765": { + "id": "HP:0000765", + "label": "Abnormal thorax morphology (HPO)" + }, + "HP:0000035": { + "id": "HP:0000035", + "label": "Abnormal testis morphology (HPO)" + }, + "HP:0002890": { + "id": "HP:0002890", + "label": "Thyroid carcinoma (HPO)" + }, + "HP:0000934": { + "id": "HP:0000934", + "label": "Chondrocalcinosis (HPO)" + }, + "HP:0002672": { + "id": "HP:0002672", + "label": "Gastrointestinal carcinoma (HPO)" + }, + "HP:0002860": { + "id": "HP:0002860", + "label": "Squamous cell carcinoma (HPO)" + }, + "HP:0003777": { + "id": "HP:0003777", + "label": "Pili torti (HPO)" + }, + "HP:0011001": { + "id": "HP:0011001", + "label": "Increased bone mineral density (HPO)" + }, + "HP:0005177": { + "id": "HP:0005177", + "label": "Premature arteriosclerosis (HPO)" + }, + "HP:0010468": { + "id": "HP:0010468", + "label": "Aplasia/Hypoplasia of the testes (HPO)" + }, + "HP:0001608": { + "id": "HP:0001608", + "label": "Abnormality of the voice (HPO)" + }, + "HP:0012060": { + "id": "HP:0012060", + "label": "Acral lentiginous melanoma (HPO)" + }, + "HP:0000144": { + "id": "HP:0000144", + "label": "Decreased fertility (HPO)" + }, + "HP:0001601": { + "id": "HP:0001601", + "label": "Laryngomalacia (HPO)" + }, + "HP:0001387": { + "id": "HP:0001387", + "label": "Joint stiffness (HPO)" + }, + "HP:0002669": { + "id": "HP:0002669", + "label": "Osteosarcoma (HPO)" + }, + "HP:0000819": { + "id": "HP:0000819", + "label": "Diabetes mellitus (HPO)" + }, + "HP:0002155": { + "id": "HP:0002155", + "label": "Hypertriglyceridemia (HPO)" + }, + "HP:0007703": { + "id": "HP:0007703", + "label": "Abnormality of retinal pigmentation (HPO)" + }, + "HP:0000518": { + "id": "HP:0000518", + "label": "Cataract (HPO)" + }, + "HP:0000444": { + "id": "HP:0000444", + "label": "Convex nasal ridge (HPO)" + }, + "HP:0200055": { + "id": "HP:0200055", + "label": "Small hand (HPO)" + }, + "HP:0004322": { + "id": "HP:0004322", + "label": "Short stature (HPO)" + }, + "HP:0100679": { + "id": "HP:0100679", + "label": "Lack of skin elasticity (HPO)" + }, + "HP:0100578": { + "id": "HP:0100578", + "label": "Lipoatrophy (HPO)" + }, + "HP:0100324": { + "id": "HP:0100324", + "label": "Scleroderma (HPO)" + }, + "HP:0031964": { + "id": "HP:0031964", + "label": "Elevated circulating alanine aminotransferase concentration (HPO)" + }, + "HP:0003419": { + "id": "HP:0003419", + "label": "Low back pain (HPO)" + }, + "HP:0100833": { + "id": "HP:0100833", + "label": "Neoplasm of the small intestine (HPO)" + }, + "HP:0005978": { + "id": "HP:0005978", + "label": "Type II diabetes mellitus (HPO)" + }, + "HP:0001838": { + "id": "HP:0001838", + "label": "Rocker bottom foot (HPO)" + }, + "HP:0003202": { + "id": "HP:0003202", + "label": "Skeletal muscle atrophy (HPO)" + }, + "HP:0007618": { + "id": "HP:0007618", + "label": "Subcutaneous calcification (HPO)" + }, + "HP:0000275": { + "id": "HP:0000275", + "label": "Narrow face (HPO)" + }, + "HP:0000962": { + "id": "HP:0000962", + "label": "Hyperkeratosis (HPO)" + }, + "HP:0000546": { + "id": "HP:0000546", + "label": "Retinal degeneration (HPO)" + }, + "HP:0008065": { + "id": "HP:0008065", + "label": "Aplasia/Hypoplasia of the skin (HPO)" + }, + "HP:0100615": { + "id": "HP:0100615", + "label": "Ovarian neoplasm (HPO)" + }, + "HP:0100649": { + "id": "HP:0100649", + "label": "Neoplasm of the oral cavity (HPO)" + }, + "HP:0002858": { + "id": "HP:0002858", + "label": "Meningioma (HPO)" + }, + "HP:0100526": { + "id": "HP:0100526", + "label": "Neoplasm of the lung (HPO)" + }, + "HP:0001635": { + "id": "HP:0001635", + "label": "Congestive heart failure (HPO)" + }, + "HP:0009726": { + "id": "HP:0009726", + "label": "Renal neoplasm (HPO)" + }, + "HP:0001533": { + "id": "HP:0001533", + "label": "Slender build (HPO)" + }, + "HP:0100242": { + "id": "HP:0100242", + "label": "Sarcoma (HPO)" + }, + "HP:0031956": { + "id": "HP:0031956", + "label": "Elevated circulating aspartate aminotransferase concentration (HPO)" } }, "object_termset": { - "HP:0004325": { - "id": "HP:0004325", - "label": "Decreased body weight (HPO)" + "HP:0002758": { + "id": "HP:0002758", + "label": "Osteoarthritis (HPO)" + }, + "HP:0002020": { + "id": "HP:0002020", + "label": "Gastroesophageal reflux (HPO)" + }, + "HP:0007495": { + "id": "HP:0007495", + "label": "Prematurely aged appearance (HPO)" + }, + "HP:0000286": { + "id": "HP:0000286", + "label": "Epicanthus (HPO)" + }, + "HP:0000481": { + "id": "HP:0000481", + "label": "Abnormal cornea morphology (HPO)" + }, + "HP:0001386": { + "id": "HP:0001386", + "label": "Joint swelling (HPO)" + }, + "HP:0003771": { + "id": "HP:0003771", + "label": "Pulp calcification (HPO)" + }, + "HP:0001252": { + "id": "HP:0001252", + "label": "Hypotonia (HPO)" + }, + "HP:0030009": { + "id": "HP:0030009", + "label": "Cervical insufficiency (HPO)" + }, + "HP:0004947": { + "id": "HP:0004947", + "label": "Arteriovenous fistula (HPO)" + }, + "HP:0002827": { + "id": "HP:0002827", + "label": "Hip dislocation (HPO)" + }, + "HP:0003394": { + "id": "HP:0003394", + "label": "Muscle spasm (HPO)" + }, + "HP:0004872": { + "id": "HP:0004872", + "label": "Incisional hernia (HPO)" + }, + "HP:0002650": { + "id": "HP:0002650", + "label": "Scoliosis (HPO)" + }, + "HP:0001075": { + "id": "HP:0001075", + "label": "Atrophic scars (HPO)" + }, + "HP:0031653": { + "id": "HP:0031653", + "label": "Abnormal heart valve physiology (HPO)" + }, + "HP:0000023": { + "id": "HP:0000023", + "label": "Inguinal hernia (HPO)" + }, + "HP:0003010": { + "id": "HP:0003010", + "label": "Prolonged bleeding time (HPO)" + }, + "HP:0025019": { + "id": "HP:0025019", + "label": "Arterial rupture (HPO)" + }, + "HP:0002829": { + "id": "HP:0002829", + "label": "Arthralgia (HPO)" + }, + "HP:0012378": { + "id": "HP:0012378", + "label": "Fatigue (HPO)" + }, + "HP:0002018": { + "id": "HP:0002018", + "label": "Nausea (HPO)" + }, + "HP:0004944": { + "id": "HP:0004944", + "label": "Dilatation of the cerebral artery (HPO)" + }, + "HP:0009763": { + "id": "HP:0009763", + "label": "Limb pain (HPO)" + }, + "HP:0001065": { + "id": "HP:0001065", + "label": "Striae distensae (HPO)" + }, + "HP:0001622": { + "id": "HP:0001622", + "label": "Premature birth (HPO)" + }, + "HP:0000978": { + "id": "HP:0000978", + "label": "Bruising susceptibility (HPO)" + }, + "HP:0010749": { + "id": "HP:0010749", + "label": "Blepharochalasis (HPO)" + }, + "HP:0002616": { + "id": "HP:0002616", + "label": "Aortic root aneurysm (HPO)" + }, + "HP:0001634": { + "id": "HP:0001634", + "label": "Mitral valve prolapse (HPO)" + }, + "HP:0000938": { + "id": "HP:0000938", + "label": "Osteopenia (HPO)" + }, + "HP:0002035": { + "id": "HP:0002035", + "label": "Rectal prolapse (HPO)" + }, + "HP:0001704": { + "id": "HP:0001704", + "label": "Tricuspid valve prolapse (HPO)" + }, + "HP:0001788": { + "id": "HP:0001788", + "label": "Premature rupture of membranes (HPO)" + }, + "HP:0001763": { + "id": "HP:0001763", + "label": "Pes planus (HPO)" + }, + "HP:0010754": { + "id": "HP:0010754", + "label": "Abnormality of the temporomandibular joint (HPO)" + }, + "HP:0002315": { + "id": "HP:0002315", + "label": "Headache (HPO)" + }, + "HP:0003083": { + "id": "HP:0003083", + "label": "Dislocated radial head (HPO)" + }, + "HP:0001058": { + "id": "HP:0001058", + "label": "Poor wound healing (HPO)" + }, + "HP:0000974": { + "id": "HP:0000974", + "label": "Hyperextensible skin (HPO)" + }, + "HP:0003834": { + "id": "HP:0003834", + "label": "Shoulder dislocation (HPO)" + }, + "HP:0001027": { + "id": "HP:0001027", + "label": "Soft, doughy skin (HPO)" + }, + "HP:0001270": { + "id": "HP:0001270", + "label": "Motor delay (HPO)" + }, + "HP:0012450": { + "id": "HP:0012450", + "label": "Chronic constipation (HPO)" + }, + "HP:0000993": { + "id": "HP:0000993", + "label": "Molluscoid pseudotumors (HPO)" + }, + "HP:0002013": { + "id": "HP:0002013", + "label": "Vomiting (HPO)" + }, + "HP:0010750": { + "id": "HP:0010750", + "label": "Dermatochalasis (HPO)" + }, + "HP:0001760": { + "id": "HP:0001760", + "label": "Abnormal foot morphology (HPO)" + }, + "HP:0002761": { + "id": "HP:0002761", + "label": "Generalized joint laxity (HPO)" + }, + "HP:0000139": { + "id": "HP:0000139", + "label": "Uterine prolapse (HPO)" + }, + "HP:0005294": { + "id": "HP:0005294", + "label": "Arterial dissection (HPO)" + }, + "HP:0000015": { + "id": "HP:0000015", + "label": "Bladder diverticulum (HPO)" + }, + "HP:0031364": { + "id": "HP:0031364", + "label": "Ecchymosis (HPO)" + }, + "HP:0002036": { + "id": "HP:0002036", + "label": "Hiatus hernia (HPO)" + }, + "HP:0025014": { + "id": "HP:0025014", + "label": "Subcutaneous spheroids (HPO)" + }, + "HP:0006243": { + "id": "HP:0006243", + "label": "Phalangeal dislocation (HPO)" + }, + "HP:0002999": { + "id": "HP:0002999", + "label": "Patellar dislocation (HPO)" + }, + "HP:0025509": { + "id": "HP:0025509", + "label": "Piezogenic pedal papules (HPO)" + }, + "HP:0001063": { + "id": "HP:0001063", + "label": "Acrocyanosis (HPO)" + }, + "HP:0001324": { + "id": "HP:0001324", + "label": "Muscle weakness (HPO)" + }, + "HP:0001653": { + "id": "HP:0001653", + "label": "Mitral regurgitation (HPO)" + }, + "HP:0001762": { + "id": "HP:0001762", + "label": "Talipes equinovarus (HPO)" + }, + "HP:0001030": { + "id": "HP:0001030", + "label": "Fragile skin (HPO)" + }, + "HP:0001537": { + "id": "HP:0001537", + "label": "Umbilical hernia (HPO)" + }, + "HP:0001278": { + "id": "HP:0001278", + "label": "Orthostatic hypotension (HPO)" + }, + "HP:0001073": { + "id": "HP:0001073", + "label": "Cigarette-paper scars (HPO)" } }, "subject_best_matches": { - "MP:0002169": { - "match_source": "MP:0002169", - "match_source_label": "no abnormal phenotype detected (MPO)", - "match_target": "HP:0004325", - "match_target_label": "Decreased body weight (HPO)", - "score": 1.4431977534690428, + "HP:0000035": { + "match_source": "HP:0000035", + "match_source_label": "Abnormal testis morphology (HPO)", + "match_target": "HP:0000139", + "match_target_label": "Uterine prolapse (HPO)", + "score": 10.48204782739082, "match_subsumer": null, "match_subsumer_label": null, "similarity": { - "subject_id": "MP:0002169", + "subject_id": "HP:0000035", "subject_label": null, "subject_source": null, - "object_id": "HP:0004325", + "object_id": "HP:0000139", "object_label": null, "object_source": null, - "ancestor_id": "UPHENO:0001003", + "ancestor_id": "HP:0000812", "ancestor_label": "", "ancestor_source": null, "object_information_content": null, "subject_information_content": null, - "ancestor_information_content": 1.4431977534690428, - "jaccard_similarity": 0.16216216216216217, + "ancestor_information_content": 10.48204782739082, + "jaccard_similarity": 0.2753623188405797, "cosine_similarity": null, "dice_similarity": null, - "phenodigm_score": 0.48376861011243283 + "phenodigm_score": 1.6989293675571675 } }, - "MP:0010771": { - "match_source": "MP:0010771", - "match_source_label": "integument phenotype (MPO)", - "match_target": "HP:0004325", - "match_target_label": "Decreased body weight (HPO)", - "score": 1.4431977534690428, + "HP:0000135": { + "match_source": "HP:0000135", + "match_source_label": "Hypogonadism (HPO)", + "match_target": "HP:0000139", + "match_target_label": "Uterine prolapse (HPO)", + "score": 9.248307728351065, "match_subsumer": null, "match_subsumer_label": null, "similarity": { - "subject_id": "MP:0010771", + "subject_id": "HP:0000135", "subject_label": null, "subject_source": null, - "object_id": "HP:0004325", + "object_id": "HP:0000139", "object_label": null, "object_source": null, - "ancestor_id": "UPHENO:0001003", + "ancestor_id": "HP:0000078", "ancestor_label": "", "ancestor_source": null, "object_information_content": null, "subject_information_content": null, - "ancestor_information_content": 1.4431977534690428, - "jaccard_similarity": 0.3333333333333333, + "ancestor_information_content": 9.248307728351065, + "jaccard_similarity": 0.35802469135802467, "cosine_similarity": null, "dice_similarity": null, - "phenodigm_score": 0.6935891563620457 + "phenodigm_score": 1.8196490101189637 } - } - }, - "object_best_matches": { - "HP:0004325": { - "match_source": "HP:0004325", - "match_source_label": "Decreased body weight (HPO)", - "match_target": "MP:0010771", - "match_target_label": "integument phenotype (MPO)", - "score": 1.4431977534690428, + }, + "HP:0000144": { + "match_source": "HP:0000144", + "match_source_label": "Decreased fertility (HPO)", + "match_target": "HP:0000139", + "match_target_label": "Uterine prolapse (HPO)", + "score": 9.248307728351065, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000144", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000139", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000078", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.248307728351065, + "jaccard_similarity": 0.37142857142857144, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.8533984265864836 + } + }, + "HP:0000275": { + "match_source": "HP:0000275", + "match_source_label": "Narrow face (HPO)", + "match_target": "HP:0010749", + "match_target_label": "Blepharochalasis (HPO)", + "score": 12.311317525876866, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000275", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0010749", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0001999", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 12.311317525876866, + "jaccard_similarity": 0.37735849056603776, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.1554072001466684 + } + }, + "HP:0000320": { + "match_source": "HP:0000320", + "match_source_label": "Bird-like facies (HPO)", + "match_target": "HP:0010749", + "match_target_label": "Blepharochalasis (HPO)", + "score": 12.311317525876866, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000320", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0010749", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0001999", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 12.311317525876866, + "jaccard_similarity": 0.41237113402061853, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.2531826311761236 + } + }, + "HP:0000444": { + "match_source": "HP:0000444", + "match_source_label": "Convex nasal ridge (HPO)", + "match_target": "HP:0010750", + "match_target_label": "Dermatochalasis (HPO)", + "score": 6.972103772193684, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000444", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0010750", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000271", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 6.972103772193684, + "jaccard_similarity": 0.5853658536585366, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.0202058005079726 + } + }, + "HP:0000518": { + "match_source": "HP:0000518", + "match_source_label": "Cataract (HPO)", + "match_target": "HP:0000481", + "match_target_label": "Abnormal cornea morphology (HPO)", + "score": 10.22992919903621, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000518", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000481", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0004328", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.22992919903621, + "jaccard_similarity": 0.825, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.905114729095027 + } + }, + "HP:0000546": { + "match_source": "HP:0000546", + "match_source_label": "Retinal degeneration (HPO)", + "match_target": "HP:0000481", + "match_target_label": "Abnormal cornea morphology (HPO)", + "score": 8.747985041127253, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000546", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000481", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0012372", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.747985041127253, + "jaccard_similarity": 0.65, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.384573395123898 + } + }, + "HP:0000765": { + "match_source": "HP:0000765", + "match_source_label": "Abnormal thorax morphology (HPO)", + "match_target": "HP:0003834", + "match_target_label": "Shoulder dislocation (HPO)", + "score": 10.48204782739082, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000765", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0003834", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000765", + "ancestor_label": "Abnormal thorax morphology (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.48204782739082, + "jaccard_similarity": 0.7323943661971831, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.7707386695591594 + } + }, + "HP:0000819": { + "match_source": "HP:0000819", + "match_source_label": "Diabetes mellitus (HPO)", + "match_target": "HP:0010749", + "match_target_label": "Blepharochalasis (HPO)", + "score": 9.456894350162482, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000819", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0010749", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0012337", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.456894350162482, + "jaccard_similarity": 0.24545454545454545, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.523560863284034 + } + }, + "HP:0000822": { + "match_source": "HP:0000822", + "match_source_label": "Hypertension (HPO)", + "match_target": "HP:0001278", + "match_target_label": "Orthostatic hypotension (HPO)", + "score": 13.363784945771002, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000822", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001278", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0030972", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 13.363784945771002, + "jaccard_similarity": 0.7538461538461538, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.1739939952993925 + } + }, + "HP:0000855": { + "match_source": "HP:0000855", + "match_source_label": "Insulin resistance (HPO)", + "match_target": "HP:0001386", + "match_target_label": "Joint swelling (HPO)", + "score": 9.456894350162482, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000855", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001386", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0012337", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.456894350162482, + "jaccard_similarity": 0.375, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.8831716282142026 + } + }, + "HP:0000869": { + "match_source": "HP:0000869", + "match_source_label": "Secondary amenorrhea (HPO)", + "match_target": "HP:0000139", + "match_target_label": "Uterine prolapse (HPO)", + "score": 10.50396260381926, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000869", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000139", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0010460", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.50396260381926, + "jaccard_similarity": 0.42857142857142855, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.12172058923405 + } + }, + "HP:0000934": { + "match_source": "HP:0000934", + "match_source_label": "Chondrocalcinosis (HPO)", + "match_target": "HP:0000023", + "match_target_label": "Inguinal hernia (HPO)", + "score": 9.880267708609392, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000934", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000023", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0003549", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.880267708609392, + "jaccard_similarity": 0.3561643835616438, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.8758996396025238 + } + }, + "HP:0000939": { + "match_source": "HP:0000939", + "match_source_label": "Osteoporosis (HPO)", + "match_target": "HP:0000938", + "match_target_label": "Osteopenia (HPO)", + "score": 13.870744934490885, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000939", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000938", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0004349", + "ancestor_label": "Reduced bone mineral density (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 13.870744934490885, + "jaccard_similarity": 0.9583333333333334, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.6459288568055053 + } + }, + "HP:0000962": { + "match_source": "HP:0000962", + "match_source_label": "Hyperkeratosis (HPO)", + "match_target": "HP:0001063", + "match_target_label": "Acrocyanosis (HPO)", + "score": 11.273182396990094, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000962", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001063", + "object_label": null, + "object_source": null, + "ancestor_id": "UPHENO:0081431", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 11.273182396990094, + "jaccard_similarity": 0.4470588235294118, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.2449444669815035 + } + }, + "HP:0001387": { + "match_source": "HP:0001387", + "match_source_label": "Joint stiffness (HPO)", + "match_target": "HP:0002761", + "match_target_label": "Generalized joint laxity (HPO)", + "score": 9.999731375210962, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001387", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0002761", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011729", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.999731375210962, + "jaccard_similarity": 0.8222222222222222, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.8674032421253965 + } + }, + "HP:0001533": { + "match_source": "HP:0001533", + "match_source_label": "Slender build (HPO)", + "match_target": "HP:0000286", + "match_target_label": "Epicanthus (HPO)", + "score": 5.92483911538792, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001533", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000286", + "object_label": null, + "object_source": null, + "ancestor_id": "UPHENO:0065599", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 5.92483911538792, + "jaccard_similarity": 0.21666666666666667, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.133011536422901 + } + }, + "HP:0001601": { + "match_source": "HP:0001601", + "match_source_label": "Laryngomalacia (HPO)", + "match_target": "HP:0002616", + "match_target_label": "Aortic root aneurysm (HPO)", + "score": 4.695950627033859, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001601", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0002616", + "object_label": null, + "object_source": null, + "ancestor_id": "UBERON:0013522", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 4.695950627033859, + "jaccard_similarity": 0.2815533980582524, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.1498525366998866 + } + }, + "HP:0001608": { + "match_source": "HP:0001608", + "match_source_label": "Abnormality of the voice (HPO)", + "match_target": "HP:0002315", + "match_target_label": "Headache (HPO)", + "score": 4.11867244793447, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001608", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0002315", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000118", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 4.11867244793447, + "jaccard_similarity": 0.59375, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.5637972266125464 + } + }, + "HP:0001620": { + "match_source": "HP:0001620", + "match_source_label": "High pitched voice (HPO)", + "match_target": "HP:0002035", + "match_target_label": "Rectal prolapse (HPO)", + "score": 4.11867244793447, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001620", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0002035", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000118", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 4.11867244793447, + "jaccard_similarity": 0.2898550724637681, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.0926198336340829 + } + }, + "HP:0001635": { + "match_source": "HP:0001635", + "match_source_label": "Congestive heart failure (HPO)", + "match_target": "HP:0031364", + "match_target_label": "Ecchymosis (HPO)", + "score": 9.47121402147955, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001635", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0031364", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011025", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.47121402147955, + "jaccard_similarity": 0.4111111111111111, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.973251458872283 + } + }, + "HP:0001838": { + "match_source": "HP:0001838", + "match_source_label": "Rocker bottom foot (HPO)", + "match_target": "HP:0002827", + "match_target_label": "Hip dislocation (HPO)", + "score": 10.548816839603521, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001838", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0002827", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0100491", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.548816839603521, + "jaccard_similarity": 0.5521472392638037, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.4134001109402905 + } + }, + "HP:0002155": { + "match_source": "HP:0002155", + "match_source_label": "Hypertriglyceridemia (HPO)", + "match_target": "HP:0031364", + "match_target_label": "Ecchymosis (HPO)", + "score": 7.52061994777287, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002155", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0031364", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0001871", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.52061994777287, + "jaccard_similarity": 0.20945945945945946, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.255095609529622 + } + }, + "HP:0002209": { + "match_source": "HP:0002209", + "match_source_label": "Sparse scalp hair (HPO)", + "match_target": "HP:0031364", + "match_target_label": "Ecchymosis (HPO)", + "score": 8.577575832584946, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002209", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0031364", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011121", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.577575832584946, + "jaccard_similarity": 0.28125, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.5532041729645578 + } + }, + "HP:0002211": { + "match_source": "HP:0002211", + "match_source_label": "White forelock (HPO)", + "match_target": "HP:0025014", + "match_target_label": "Subcutaneous spheroids (HPO)", + "score": 8.577575832584946, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002211", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0025014", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011121", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.577575832584946, + "jaccard_similarity": 0.37362637362637363, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.7901979088452584 + } + }, + "HP:0002216": { + "match_source": "HP:0002216", + "match_source_label": "Premature graying of hair (HPO)", + "match_target": "HP:0007495", + "match_target_label": "Prematurely aged appearance (HPO)", + "score": 14.418232729793377, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002216", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0007495", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0007495", + "ancestor_label": "Prematurely aged appearance (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 14.418232729793377, + "jaccard_similarity": 0.5454545454545454, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.804369907820168 + } + }, + "HP:0002293": { + "match_source": "HP:0002293", + "match_source_label": "Alopecia of scalp (HPO)", + "match_target": "HP:0025509", + "match_target_label": "Piezogenic pedal papules (HPO)", + "score": 8.17615794259523, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002293", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0025509", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000951", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.17615794259523, + "jaccard_similarity": 0.3764705882352941, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.7544466336008908 + } + }, + "HP:0002621": { + "match_source": "HP:0002621", + "match_source_label": "Atherosclerosis (HPO)", + "match_target": "HP:0002616", + "match_target_label": "Aortic root aneurysm (HPO)", + "score": 9.989389430989503, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002621", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0002616", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011004", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.989389430989503, + "jaccard_similarity": 0.48936170212765956, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.2109782032315644 + } + }, + "HP:0002664": { + "match_source": "HP:0002664", + "match_source_label": "Neoplasm (HPO)", + "match_target": "HP:0002035", + "match_target_label": "Rectal prolapse (HPO)", + "score": 7.312122825948508, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002664", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0002035", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0002664", + "ancestor_label": "Neoplasm (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.312122825948508, + "jaccard_similarity": 0.27692307692307694, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.42298824724631 + } + }, + "HP:0002669": { + "match_source": "HP:0002669", + "match_source_label": "Osteosarcoma (HPO)", + "match_target": "HP:0004872", + "match_target_label": "Incisional hernia (HPO)", + "score": 7.3529719602833685, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002669", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0004872", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011793", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.3529719602833685, + "jaccard_similarity": 0.3582089552238806, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.622929574468219 + } + }, + "HP:0002672": { + "match_source": "HP:0002672", + "match_source_label": "Gastrointestinal carcinoma (HPO)", + "match_target": "HP:0002035", + "match_target_label": "Rectal prolapse (HPO)", + "score": 9.752350233688654, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002672", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0002035", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011024", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.752350233688654, + "jaccard_similarity": 0.39705882352941174, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.967805048889549 + } + }, + "HP:0002858": { + "match_source": "HP:0002858", + "match_source_label": "Meningioma (HPO)", + "match_target": "HP:0004944", + "match_target_label": "Dilatation of the cerebral artery (HPO)", + "score": 8.210279827160718, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002858", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0004944", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0002011", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.210279827160718, + "jaccard_similarity": 0.36, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.719215151683424 + } + }, + "HP:0002860": { + "match_source": "HP:0002860", + "match_source_label": "Squamous cell carcinoma (HPO)", + "match_target": "HP:0001075", + "match_target_label": "Atrophic scars (HPO)", + "score": 8.17615794259523, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002860", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001075", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000951", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.17615794259523, + "jaccard_similarity": 0.5, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.0218998420539074 + } + }, + "HP:0002861": { + "match_source": "HP:0002861", + "match_source_label": "Melanoma (HPO)", + "match_target": "HP:0000023", + "match_target_label": "Inguinal hernia (HPO)", + "score": 7.312122825948508, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002861", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000023", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0002664", + "ancestor_label": "Neoplasm (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.312122825948508, + "jaccard_similarity": 0.3103448275862069, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.5064127912720862 + } + }, + "HP:0002890": { + "match_source": "HP:0002890", + "match_source_label": "Thyroid carcinoma (HPO)", + "match_target": "HP:0003771", + "match_target_label": "Pulp calcification (HPO)", + "score": 7.3529719602833685, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002890", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0003771", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011793", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.3529719602833685, + "jaccard_similarity": 0.211864406779661, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.2481318209359606 + } + }, + "HP:0003002": { + "match_source": "HP:0003002", + "match_source_label": "Breast carcinoma (HPO)", + "match_target": "HP:0003834", + "match_target_label": "Shoulder dislocation (HPO)", + "score": 10.48204782739082, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0003002", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0003834", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000765", + "ancestor_label": "Abnormal thorax morphology (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.48204782739082, + "jaccard_similarity": 0.6341463414634146, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.5782071834483014 + } + }, + "HP:0003202": { + "match_source": "HP:0003202", + "match_source_label": "Skeletal muscle atrophy (HPO)", + "match_target": "HP:0001065", + "match_target_label": "Striae distensae (HPO)", + "score": 10.025915307014618, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0003202", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001065", + "object_label": null, + "object_source": null, + "ancestor_id": "UPHENO:0013936", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.025915307014618, + "jaccard_similarity": 0.46875, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.167867108510829 + } + }, + "HP:0003419": { + "match_source": "HP:0003419", + "match_source_label": "Low back pain (HPO)", + "match_target": "HP:0002829", + "match_target_label": "Arthralgia (HPO)", + "score": 12.074278328576016, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0003419", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0002829", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0012531", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 12.074278328576016, + "jaccard_similarity": 0.38, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.1420144175189124 + } + }, + "HP:0003777": { + "match_source": "HP:0003777", + "match_source_label": "Pili torti (HPO)", + "match_target": "HP:0000974", + "match_target_label": "Hyperextensible skin (HPO)", + "score": 8.17615794259523, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0003777", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000974", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000951", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.17615794259523, + "jaccard_similarity": 0.5079365079365079, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.0378834887449195 + } + }, + "HP:0004322": { + "match_source": "HP:0004322", + "match_source_label": "Short stature (HPO)", + "match_target": "HP:0001065", + "match_target_label": "Striae distensae (HPO)", + "score": 5.614598333413893, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0004322", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001065", + "object_label": null, + "object_source": null, + "ancestor_id": "UPHENO:0012541", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 5.614598333413893, + "jaccard_similarity": 0.37681159420289856, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.4545259532997774 + } + }, + "HP:0004349": { + "match_source": "HP:0004349", + "match_source_label": "Reduced bone mineral density (HPO)", + "match_target": "HP:0000938", + "match_target_label": "Osteopenia (HPO)", + "score": 13.870744934490885, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0004349", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000938", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0004349", + "ancestor_label": "Reduced bone mineral density (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 13.870744934490885, + "jaccard_similarity": 0.9787234042553191, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.684511188996736 + } + }, + "HP:0004415": { + "match_source": "HP:0004415", + "match_source_label": "Pulmonary artery stenosis (HPO)", + "match_target": "HP:0002616", + "match_target_label": "Aortic root aneurysm (HPO)", + "score": 10.587290987418157, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0004415", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0002616", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0030962", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.587290987418157, + "jaccard_similarity": 0.5118110236220472, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.3278084624072837 + } + }, + "HP:0005177": { + "match_source": "HP:0005177", + "match_source_label": "Premature arteriosclerosis (HPO)", + "match_target": "HP:0004944", + "match_target_label": "Dilatation of the cerebral artery (HPO)", + "score": 9.989389430989503, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0005177", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0004944", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011004", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.989389430989503, + "jaccard_similarity": 0.48936170212765956, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.2109782032315644 + } + }, + "HP:0005328": { + "match_source": "HP:0005328", + "match_source_label": "Progeroid facial appearance (HPO)", + "match_target": "HP:0007495", + "match_target_label": "Prematurely aged appearance (HPO)", + "score": 14.418232729793377, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0005328", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0007495", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0007495", + "ancestor_label": "Prematurely aged appearance (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 14.418232729793377, + "jaccard_similarity": 0.972972972972973, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.7454706999419027 + } + }, + "HP:0005978": { + "match_source": "HP:0005978", + "match_source_label": "Type II diabetes mellitus (HPO)", + "match_target": "HP:0001386", + "match_target_label": "Joint swelling (HPO)", + "score": 9.456894350162482, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0005978", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001386", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0012337", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.456894350162482, + "jaccard_similarity": 0.33783783783783783, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.7874274082937627 + } + }, + "HP:0007495": { + "match_source": "HP:0007495", + "match_source_label": "Prematurely aged appearance (HPO)", + "match_target": "HP:0007495", + "match_target_label": "Prematurely aged appearance (HPO)", + "score": 14.418232729793377, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0007495", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0007495", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0007495", + "ancestor_label": "Prematurely aged appearance (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 14.418232729793377, + "jaccard_similarity": 1, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.797134805322742 + } + }, + "HP:0007618": { + "match_source": "HP:0007618", + "match_source_label": "Subcutaneous calcification (HPO)", + "match_target": "HP:0000978", + "match_target_label": "Bruising susceptibility (HPO)", + "score": 14.533709947213314, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0007618", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000978", + "object_label": null, + "object_source": null, + "ancestor_id": "UBERON:0011818", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 14.533709947213314, + "jaccard_similarity": 0.42696629213483145, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.4910648821587897 + } + }, + "HP:0007703": { + "match_source": "HP:0007703", + "match_source_label": "Abnormality of retinal pigmentation (HPO)", + "match_target": "HP:0000481", + "match_target_label": "Abnormal cornea morphology (HPO)", + "score": 8.747985041127253, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0007703", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000481", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0012372", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.747985041127253, + "jaccard_similarity": 0.625, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.3382665910251834 + } + }, + "HP:0008065": { + "match_source": "HP:0008065", + "match_source_label": "Aplasia/Hypoplasia of the skin (HPO)", + "match_target": "HP:0001075", + "match_target_label": "Atrophic scars (HPO)", + "score": 13.659240829297172, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0008065", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001075", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0008065", + "ancestor_label": "Aplasia/Hypoplasia of the skin (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 13.659240829297172, + "jaccard_similarity": 0.6964285714285714, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.0842641873786114 + } + }, + "HP:0009125": { + "match_source": "HP:0009125", + "match_source_label": "Lipodystrophy (HPO)", + "match_target": "HP:0001073", + "match_target_label": "Cigarette-paper scars (HPO)", + "score": 9.880267708609392, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0009125", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001073", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0003549", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.880267708609392, + "jaccard_similarity": 0.40625, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.0034616933254714 + } + }, + "HP:0009726": { + "match_source": "HP:0009726", + "match_source_label": "Renal neoplasm (HPO)", + "match_target": "HP:0000015", + "match_target_label": "Bladder diverticulum (HPO)", + "score": 8.160119732503459, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0009726", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000015", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000079", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.160119732503459, + "jaccard_similarity": 0.45, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.9162603893068804 + } + }, + "HP:0010468": { + "match_source": "HP:0010468", + "match_source_label": "Aplasia/Hypoplasia of the testes (HPO)", + "match_target": "HP:0030009", + "match_target_label": "Cervical insufficiency (HPO)", + "score": 10.48204782739082, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0010468", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0030009", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000812", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.48204782739082, + "jaccard_similarity": 0.2753623188405797, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.6989293675571675 + } + }, + "HP:0010721": { + "match_source": "HP:0010721", + "match_source_label": "Abnormal hair whorl (HPO)", + "match_target": "HP:0001065", + "match_target_label": "Striae distensae (HPO)", + "score": 8.577575832584946, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0010721", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001065", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011121", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.577575832584946, + "jaccard_similarity": 0.45121951219512196, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.9673254898454517 + } + }, + "HP:0011001": { + "match_source": "HP:0011001", + "match_source_label": "Increased bone mineral density (HPO)", + "match_target": "HP:0000938", + "match_target_label": "Osteopenia (HPO)", + "score": 10.564083596256832, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0011001", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000938", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0004348", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.564083596256832, + "jaccard_similarity": 0.86, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.014151935915122 + } + }, + "HP:0012056": { + "match_source": "HP:0012056", + "match_source_label": "Cutaneous melanoma (HPO)", + "match_target": "HP:0001027", + "match_target_label": "Soft, doughy skin (HPO)", + "score": 8.17615794259523, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0012056", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001027", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000951", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.17615794259523, + "jaccard_similarity": 0.6976744186046512, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.388366856037809 + } + }, + "HP:0012060": { + "match_source": "HP:0012060", + "match_source_label": "Acral lentiginous melanoma (HPO)", + "match_target": "HP:0000993", + "match_target_label": "Molluscoid pseudotumors (HPO)", + "score": 8.17615794259523, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0012060", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000993", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000951", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.17615794259523, + "jaccard_similarity": 0.6976744186046512, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.388366856037809 + } + }, + "HP:0031956": { + "match_source": "HP:0031956", + "match_source_label": "Elevated circulating aspartate aminotransferase concentration (HPO)", + "match_target": "HP:0010749", + "match_target_label": "Blepharochalasis (HPO)", + "score": 7.283411529306981, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0031956", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0010749", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0001939", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.283411529306981, + "jaccard_similarity": 0.1746031746031746, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.1276997716406445 + } + }, + "HP:0031964": { + "match_source": "HP:0031964", + "match_source_label": "Elevated circulating alanine aminotransferase concentration (HPO)", + "match_target": "HP:0010749", + "match_target_label": "Blepharochalasis (HPO)", + "score": 7.283411529306981, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0031964", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0010749", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0001939", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.283411529306981, + "jaccard_similarity": 0.1746031746031746, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.1276997716406445 + } + }, + "HP:0040217": { + "match_source": "HP:0040217", + "match_source_label": "Elevated hemoglobin A1c (HPO)", + "match_target": "HP:0031364", + "match_target_label": "Ecchymosis (HPO)", + "score": 7.52061994777287, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0040217", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0031364", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0001871", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.52061994777287, + "jaccard_similarity": 0.18604651162790697, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.182871551167917 + } + }, + "HP:0100242": { + "match_source": "HP:0100242", + "match_source_label": "Sarcoma (HPO)", + "match_target": "HP:0004872", + "match_target_label": "Incisional hernia (HPO)", + "score": 7.312122825948508, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0100242", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0004872", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0002664", + "ancestor_label": "Neoplasm (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.312122825948508, + "jaccard_similarity": 0.3103448275862069, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.5064127912720862 + } + }, + "HP:0100324": { + "match_source": "HP:0100324", + "match_source_label": "Scleroderma (HPO)", + "match_target": "HP:0001073", + "match_target_label": "Cigarette-paper scars (HPO)", + "score": 11.273182396990094, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0100324", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001073", + "object_label": null, + "object_source": null, + "ancestor_id": "UPHENO:0081431", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 11.273182396990094, + "jaccard_similarity": 0.609375, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.6209913245117464 + } + }, + "HP:0100526": { + "match_source": "HP:0100526", + "match_source_label": "Neoplasm of the lung (HPO)", + "match_target": "HP:0004872", + "match_target_label": "Incisional hernia (HPO)", + "score": 7.3529719602833685, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0100526", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0004872", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011793", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.3529719602833685, + "jaccard_similarity": 0.40476190476190477, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.7251675096364334 + } + }, + "HP:0100578": { + "match_source": "HP:0100578", + "match_source_label": "Lipoatrophy (HPO)", + "match_target": "HP:0001537", + "match_target_label": "Umbilical hernia (HPO)", + "score": 9.880267708609392, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0100578", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001537", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0003549", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.880267708609392, + "jaccard_similarity": 0.3424657534246575, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.8394709361297965 + } + }, + "HP:0100585": { + "match_source": "HP:0100585", + "match_source_label": "Telangiectasia of the skin (HPO)", + "match_target": "HP:0000978", + "match_target_label": "Bruising susceptibility (HPO)", + "score": 11.889853757438589, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0100585", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000978", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011276", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 11.889853757438589, + "jaccard_similarity": 0.5882352941176471, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.6446231531208184 + } + }, + "HP:0100615": { + "match_source": "HP:0100615", + "match_source_label": "Ovarian neoplasm (HPO)", + "match_target": "HP:0000139", + "match_target_label": "Uterine prolapse (HPO)", + "score": 11.350488123157543, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0100615", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000139", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000008", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 11.350488123157543, + "jaccard_similarity": 0.6133333333333333, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.6384906131227046 + } + }, + "HP:0100649": { + "match_source": "HP:0100649", + "match_source_label": "Neoplasm of the oral cavity (HPO)", + "match_target": "HP:0003771", + "match_target_label": "Pulp calcification (HPO)", + "score": 9.334037602376949, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0100649", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0003771", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000163", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.334037602376949, + "jaccard_similarity": 0.62, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.4056398968826795 + } + }, + "HP:0100659": { + "match_source": "HP:0100659", + "match_source_label": "Abnormal cerebral vascular morphology (HPO)", + "match_target": "HP:0004944", + "match_target_label": "Dilatation of the cerebral artery (HPO)", + "score": 12.11867244793447, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0100659", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0004944", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0100659", + "ancestor_label": "Abnormal cerebral vascular morphology (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 12.11867244793447, + "jaccard_similarity": 0.6551724137931034, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.8177685993851953 + } + }, + "HP:0100679": { + "match_source": "HP:0100679", + "match_source_label": "Lack of skin elasticity (HPO)", + "match_target": "HP:0001065", + "match_target_label": "Striae distensae (HPO)", + "score": 17.11867244793447, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0100679", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001065", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0100679", + "ancestor_label": "Lack of skin elasticity (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 17.11867244793447, + "jaccard_similarity": 0.7058823529411765, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.476171570388503 + } + }, + "HP:0100833": { + "match_source": "HP:0100833", + "match_source_label": "Neoplasm of the small intestine (HPO)", + "match_target": "HP:0002036", + "match_target_label": "Hiatus hernia (HPO)", + "score": 9.752350233688654, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0100833", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0002036", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011024", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.752350233688654, + "jaccard_similarity": 0.4909090909090909, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.1880396220012006 + } + }, + "HP:0200042": { + "match_source": "HP:0200042", + "match_source_label": "Skin ulcer (HPO)", + "match_target": "HP:0000993", + "match_target_label": "Molluscoid pseudotumors (HPO)", + "score": 10.72635502515571, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0200042", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000993", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011355", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.72635502515571, + "jaccard_similarity": 0.9459459459459459, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.1853652931528855 + } + }, + "HP:0200055": { + "match_source": "HP:0200055", + "match_source_label": "Small hand (HPO)", + "match_target": "HP:0006243", + "match_target_label": "Phalangeal dislocation (HPO)", + "score": 7.926379633463703, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0200055", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0006243", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0005922", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.926379633463703, + "jaccard_similarity": 0.56875, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.1232353653169214 + } + } + }, + "object_best_matches": { + "HP:0000015": { + "match_source": "HP:0000015", + "match_source_label": "Bladder diverticulum (HPO)", + "match_target": "HP:0100585", + "match_target_label": "Telangiectasia of the skin (HPO)", + "score": 9.837901677803867, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000015", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0100585", + "object_label": null, + "object_source": null, + "ancestor_id": "MPATH:56", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.837901677803867, + "jaccard_similarity": 0.31868131868131866, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.7706370265358435 + } + }, + "HP:0000023": { + "match_source": "HP:0000023", + "match_source_label": "Inguinal hernia (HPO)", + "match_target": "HP:0000934", + "match_target_label": "Chondrocalcinosis (HPO)", + "score": 9.880267708609392, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000023", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000934", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0003549", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.880267708609392, + "jaccard_similarity": 0.3561643835616438, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.8758996396025238 + } + }, + "HP:0000139": { + "match_source": "HP:0000139", + "match_source_label": "Uterine prolapse (HPO)", + "match_target": "HP:0100615", + "match_target_label": "Ovarian neoplasm (HPO)", + "score": 11.350488123157543, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000139", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0100615", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000008", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 11.350488123157543, + "jaccard_similarity": 0.6133333333333333, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.6384906131227046 + } + }, + "HP:0000286": { + "match_source": "HP:0000286", + "match_source_label": "Epicanthus (HPO)", + "match_target": "HP:0002216", + "match_target_label": "Premature graying of hair (HPO)", + "score": 8.577575832584946, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000286", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0002216", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011121", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.577575832584946, + "jaccard_similarity": 0.3089430894308943, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.6278767697668546 + } + }, + "HP:0000481": { + "match_source": "HP:0000481", + "match_source_label": "Abnormal cornea morphology (HPO)", + "match_target": "HP:0000518", + "match_target_label": "Cataract (HPO)", + "score": 10.22992919903621, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000481", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000518", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0004328", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.22992919903621, + "jaccard_similarity": 0.825, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.905114729095027 + } + }, + "HP:0000938": { + "match_source": "HP:0000938", + "match_source_label": "Osteopenia (HPO)", + "match_target": "HP:0000939", + "match_target_label": "Osteoporosis (HPO)", + "score": 13.870744934490885, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000938", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000939", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0004349", + "ancestor_label": "Reduced bone mineral density (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 13.870744934490885, + "jaccard_similarity": 0.9583333333333334, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.6459288568055053 + } + }, + "HP:0000974": { + "match_source": "HP:0000974", + "match_source_label": "Hyperextensible skin (HPO)", + "match_target": "HP:0100679", + "match_target_label": "Lack of skin elasticity (HPO)", + "score": 13.659240829297172, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000974", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0100679", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0010647", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 13.659240829297172, + "jaccard_similarity": 0.9210526315789473, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.546953581764887 + } + }, + "HP:0000978": { + "match_source": "HP:0000978", + "match_source_label": "Bruising susceptibility (HPO)", + "match_target": "HP:0007618", + "match_target_label": "Subcutaneous calcification (HPO)", + "score": 14.533709947213314, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000978", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0007618", + "object_label": null, + "object_source": null, + "ancestor_id": "UBERON:0011818", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 14.533709947213314, + "jaccard_similarity": 0.42696629213483145, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.4910648821587897 + } + }, + "HP:0000993": { + "match_source": "HP:0000993", + "match_source_label": "Molluscoid pseudotumors (HPO)", + "match_target": "HP:0200042", + "match_target_label": "Skin ulcer (HPO)", + "score": 10.72635502515571, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0000993", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0200042", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011355", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.72635502515571, + "jaccard_similarity": 0.9459459459459459, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.1853652931528855 + } + }, + "HP:0001027": { + "match_source": "HP:0001027", + "match_source_label": "Soft, doughy skin (HPO)", + "match_target": "HP:0100679", + "match_target_label": "Lack of skin elasticity (HPO)", + "score": 13.659240829297172, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001027", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0100679", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0010647", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 13.659240829297172, + "jaccard_similarity": 0.9210526315789473, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.546953581764887 + } + }, + "HP:0001030": { + "match_source": "HP:0001030", + "match_source_label": "Fragile skin (HPO)", + "match_target": "HP:0100585", + "match_target_label": "Telangiectasia of the skin (HPO)", + "score": 11.052583257476698, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001030", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0100585", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011354", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 11.052583257476698, + "jaccard_similarity": 0.603448275862069, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.5825689362621636 + } + }, + "HP:0001058": { + "match_source": "HP:0001058", + "match_source_label": "Poor wound healing (HPO)", + "match_target": "HP:0100585", + "match_target_label": "Telangiectasia of the skin (HPO)", + "score": 11.052583257476698, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001058", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0100585", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011354", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 11.052583257476698, + "jaccard_similarity": 0.603448275862069, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.5825689362621636 + } + }, + "HP:0001063": { + "match_source": "HP:0001063", + "match_source_label": "Acrocyanosis (HPO)", + "match_target": "HP:0000962", + "match_target_label": "Hyperkeratosis (HPO)", + "score": 11.273182396990094, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001063", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000962", + "object_label": null, + "object_source": null, + "ancestor_id": "UPHENO:0081431", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 11.273182396990094, + "jaccard_similarity": 0.4470588235294118, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.2449444669815035 + } + }, + "HP:0001065": { + "match_source": "HP:0001065", + "match_source_label": "Striae distensae (HPO)", + "match_target": "HP:0100679", + "match_target_label": "Lack of skin elasticity (HPO)", + "score": 17.11867244793447, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001065", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0100679", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0100679", + "ancestor_label": "Lack of skin elasticity (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 17.11867244793447, + "jaccard_similarity": 0.7058823529411765, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.476171570388503 + } + }, + "HP:0001073": { + "match_source": "HP:0001073", + "match_source_label": "Cigarette-paper scars (HPO)", + "match_target": "HP:0008065", + "match_target_label": "Aplasia/Hypoplasia of the skin (HPO)", + "score": 13.659240829297172, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001073", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0008065", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0008065", + "ancestor_label": "Aplasia/Hypoplasia of the skin (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 13.659240829297172, + "jaccard_similarity": 0.6842105263157895, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.0570895238588514 + } + }, + "HP:0001075": { + "match_source": "HP:0001075", + "match_source_label": "Atrophic scars (HPO)", + "match_target": "HP:0008065", + "match_target_label": "Aplasia/Hypoplasia of the skin (HPO)", + "score": 13.659240829297172, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001075", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0008065", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0008065", + "ancestor_label": "Aplasia/Hypoplasia of the skin (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 13.659240829297172, + "jaccard_similarity": 0.6964285714285714, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.0842641873786114 + } + }, + "HP:0001252": { + "match_source": "HP:0001252", + "match_source_label": "Hypotonia (HPO)", + "match_target": "HP:0003202", + "match_target_label": "Skeletal muscle atrophy (HPO)", + "score": 8.686130547546211, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001252", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0003202", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0003011", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.686130547546211, + "jaccard_similarity": 0.5686274509803921, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.22242486310204 + } + }, + "HP:0001270": { + "match_source": "HP:0001270", + "match_source_label": "Motor delay (HPO)", + "match_target": "HP:0007703", + "match_target_label": "Abnormality of retinal pigmentation (HPO)", + "score": 6.667976676361555, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001270", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0007703", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000707", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 6.667976676361555, + "jaccard_similarity": 0.22772277227722773, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.2322540867130238 + } + }, + "HP:0001278": { + "match_source": "HP:0001278", + "match_source_label": "Orthostatic hypotension (HPO)", + "match_target": "HP:0000822", + "match_target_label": "Hypertension (HPO)", + "score": 13.363784945771002, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001278", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000822", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0030972", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 13.363784945771002, + "jaccard_similarity": 0.7538461538461538, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.1739939952993925 + } + }, + "HP:0001324": { + "match_source": "HP:0001324", + "match_source_label": "Muscle weakness (HPO)", + "match_target": "HP:0003202", + "match_target_label": "Skeletal muscle atrophy (HPO)", + "score": 8.686130547546211, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001324", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0003202", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0003011", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.686130547546211, + "jaccard_similarity": 0.58, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.2445390880037714 + } + }, + "HP:0001386": { + "match_source": "HP:0001386", + "match_source_label": "Joint swelling (HPO)", + "match_target": "HP:0005978", + "match_target_label": "Type II diabetes mellitus (HPO)", + "score": 9.456894350162482, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001386", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0005978", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0012337", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.456894350162482, + "jaccard_similarity": 0.33783783783783783, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.7874274082937627 + } + }, + "HP:0001537": { + "match_source": "HP:0001537", + "match_source_label": "Umbilical hernia (HPO)", + "match_target": "HP:0009125", + "match_target_label": "Lipodystrophy (HPO)", + "score": 9.880267708609392, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001537", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0009125", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0003549", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.880267708609392, + "jaccard_similarity": 0.3472222222222222, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.8522009906956145 + } + }, + "HP:0001622": { + "match_source": "HP:0001622", + "match_source_label": "Premature birth (HPO)", + "match_target": "HP:0010468", + "match_target_label": "Aplasia/Hypoplasia of the testes (HPO)", + "score": 8.47301401552576, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001622", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0010468", + "object_label": null, + "object_source": null, + "ancestor_id": "UPHENO:0049940", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.47301401552576, + "jaccard_similarity": 0.20967741935483872, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.33289148580551 + } + }, + "HP:0001634": { + "match_source": "HP:0001634", + "match_source_label": "Mitral valve prolapse (HPO)", + "match_target": "HP:0100659", + "match_target_label": "Abnormal cerebral vascular morphology (HPO)", + "score": 8.449787463668223, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001634", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0100659", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0030680", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.449787463668223, + "jaccard_similarity": 0.3113207547169811, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.6219106665865655 + } + }, + "HP:0001653": { + "match_source": "HP:0001653", + "match_source_label": "Mitral regurgitation (HPO)", + "match_target": "HP:0000822", + "match_target_label": "Hypertension (HPO)", + "score": 9.47121402147955, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001653", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000822", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011025", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.47121402147955, + "jaccard_similarity": 0.32978723404255317, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.7673385287399772 + } + }, + "HP:0001704": { + "match_source": "HP:0001704", + "match_source_label": "Tricuspid valve prolapse (HPO)", + "match_target": "HP:0002621", + "match_target_label": "Atherosclerosis (HPO)", + "score": 8.449787463668223, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001704", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0002621", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0030680", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.449787463668223, + "jaccard_similarity": 0.28440366972477066, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.550209844847337 + } + }, + "HP:0001760": { + "match_source": "HP:0001760", + "match_source_label": "Abnormal foot morphology (HPO)", + "match_target": "HP:0001838", + "match_target_label": "Rocker bottom foot (HPO)", + "score": 8.268485610288696, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001760", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001838", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0001760", + "ancestor_label": "Abnormal foot morphology (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.268485610288696, + "jaccard_similarity": 0.3709677419354839, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.7513827211877018 + } + }, + "HP:0001762": { + "match_source": "HP:0001762", + "match_source_label": "Talipes equinovarus (HPO)", + "match_target": "HP:0001838", + "match_target_label": "Rocker bottom foot (HPO)", + "score": 8.268485610288696, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001762", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001838", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0001760", + "ancestor_label": "Abnormal foot morphology (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.268485610288696, + "jaccard_similarity": 0.36220472440944884, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.7305734748221788 + } + }, + "HP:0001763": { + "match_source": "HP:0001763", + "match_source_label": "Pes planus (HPO)", + "match_target": "HP:0001838", + "match_target_label": "Rocker bottom foot (HPO)", + "score": 8.268485610288696, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001763", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001838", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0001760", + "ancestor_label": "Abnormal foot morphology (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.268485610288696, + "jaccard_similarity": 0.4, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.8186242723870916 + } + }, + "HP:0001788": { + "match_source": "HP:0001788", + "match_source_label": "Premature rupture of membranes (HPO)", + "match_target": "HP:0000035", + "match_target_label": "Abnormal testis morphology (HPO)", + "score": 7.12361198090175, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0001788", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000035", + "object_label": null, + "object_source": null, + "ancestor_id": "GO:0000003", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.12361198090175, + "jaccard_similarity": 0.2, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.1936173575230673 + } + }, + "HP:0002013": { + "match_source": "HP:0002013", + "match_source_label": "Vomiting (HPO)", + "match_target": "HP:0100649", + "match_target_label": "Neoplasm of the oral cavity (HPO)", + "score": 7.826350815132431, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002013", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0100649", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0025031", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.826350815132431, + "jaccard_similarity": 0.3380281690140845, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.6265076194414532 + } + }, + "HP:0002018": { + "match_source": "HP:0002018", + "match_source_label": "Nausea (HPO)", + "match_target": "HP:0100649", + "match_target_label": "Neoplasm of the oral cavity (HPO)", + "score": 7.826350815132431, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002018", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0100649", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0025031", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.826350815132431, + "jaccard_similarity": 0.3380281690140845, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.6265076194414532 + } + }, + "HP:0002020": { + "match_source": "HP:0002020", + "match_source_label": "Gastroesophageal reflux (HPO)", + "match_target": "HP:0002672", + "match_target_label": "Gastrointestinal carcinoma (HPO)", + "score": 9.752350233688654, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002020", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0002672", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011024", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.752350233688654, + "jaccard_similarity": 0.43548387096774194, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.0608229498915955 + } + }, + "HP:0002035": { + "match_source": "HP:0002035", + "match_source_label": "Rectal prolapse (HPO)", + "match_target": "HP:0100833", + "match_target_label": "Neoplasm of the small intestine (HPO)", + "score": 9.752350233688654, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002035", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0100833", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011024", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.752350233688654, + "jaccard_similarity": 0.40298507462686567, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.9824357711437597 + } + }, + "HP:0002036": { + "match_source": "HP:0002036", + "match_source_label": "Hiatus hernia (HPO)", + "match_target": "HP:0009125", + "match_target_label": "Lipodystrophy (HPO)", + "score": 9.880267708609392, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002036", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0009125", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0003549", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.880267708609392, + "jaccard_similarity": 0.4098360655737705, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.0122847821598326 + } + }, + "HP:0002315": { + "match_source": "HP:0002315", + "match_source_label": "Headache (HPO)", + "match_target": "HP:0002858", + "match_target_label": "Meningioma (HPO)", + "score": 6.667976676361555, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002315", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0002858", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000707", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 6.667976676361555, + "jaccard_similarity": 0.42592592592592593, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.6852489845514738 + } + }, + "HP:0002616": { + "match_source": "HP:0002616", + "match_source_label": "Aortic root aneurysm (HPO)", + "match_target": "HP:0004415", + "match_target_label": "Pulmonary artery stenosis (HPO)", + "score": 10.587290987418157, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002616", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0004415", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0030962", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.587290987418157, + "jaccard_similarity": 0.5118110236220472, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.3278084624072837 + } + }, + "HP:0002650": { + "match_source": "HP:0002650", + "match_source_label": "Scoliosis (HPO)", + "match_target": "HP:0003419", + "match_target_label": "Low back pain (HPO)", + "score": 9.974014205102588, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002650", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0003419", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000925", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.974014205102588, + "jaccard_similarity": 0.8823529411764706, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.966580652739474 + } + }, + "HP:0002758": { + "match_source": "HP:0002758", + "match_source_label": "Osteoarthritis (HPO)", + "match_target": "HP:0000934", + "match_target_label": "Chondrocalcinosis (HPO)", + "score": 9.004930281885281, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002758", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000934", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0001367", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.004930281885281, + "jaccard_similarity": 0.6923076923076923, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.496834496486232 + } + }, + "HP:0002761": { + "match_source": "HP:0002761", + "match_source_label": "Generalized joint laxity (HPO)", + "match_target": "HP:0001387", + "match_target_label": "Joint stiffness (HPO)", + "score": 9.999731375210962, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002761", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001387", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011729", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.999731375210962, + "jaccard_similarity": 0.8222222222222222, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.8674032421253965 + } + }, + "HP:0002827": { + "match_source": "HP:0002827", + "match_source_label": "Hip dislocation (HPO)", + "match_target": "HP:0001838", + "match_target_label": "Rocker bottom foot (HPO)", + "score": 10.548816839603521, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002827", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001838", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0100491", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.548816839603521, + "jaccard_similarity": 0.5521472392638037, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.4134001109402905 + } + }, + "HP:0002829": { + "match_source": "HP:0002829", + "match_source_label": "Arthralgia (HPO)", + "match_target": "HP:0003419", + "match_target_label": "Low back pain (HPO)", + "score": 12.074278328576016, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002829", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0003419", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0012531", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 12.074278328576016, + "jaccard_similarity": 0.38, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.1420144175189124 + } + }, + "HP:0002999": { + "match_source": "HP:0002999", + "match_source_label": "Patellar dislocation (HPO)", + "match_target": "HP:0001838", + "match_target_label": "Rocker bottom foot (HPO)", + "score": 10.548816839603521, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0002999", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001838", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0100491", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.548816839603521, + "jaccard_similarity": 0.6834532374100719, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.6850741181339686 + } + }, + "HP:0003010": { + "match_source": "HP:0003010", + "match_source_label": "Prolonged bleeding time (HPO)", + "match_target": "HP:0002155", + "match_target_label": "Hypertriglyceridemia (HPO)", + "score": 7.52061994777287, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0003010", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0002155", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0001871", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.52061994777287, + "jaccard_similarity": 0.22429906542056074, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.2987948358646493 + } + }, + "HP:0003083": { + "match_source": "HP:0003083", + "match_source_label": "Dislocated radial head (HPO)", + "match_target": "HP:0001838", + "match_target_label": "Rocker bottom foot (HPO)", + "score": 9.004930281885281, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0003083", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0001838", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0001367", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.004930281885281, + "jaccard_similarity": 0.36764705882352944, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.8195153566392508 + } + }, + "HP:0003394": { + "match_source": "HP:0003394", + "match_source_label": "Muscle spasm (HPO)", + "match_target": "HP:0003202", + "match_target_label": "Skeletal muscle atrophy (HPO)", + "score": 8.686130547546211, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0003394", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0003202", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0003011", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 8.686130547546211, + "jaccard_similarity": 0.6041666666666666, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.2908231138921447 + } + }, + "HP:0003771": { + "match_source": "HP:0003771", + "match_source_label": "Pulp calcification (HPO)", + "match_target": "HP:0000934", + "match_target_label": "Chondrocalcinosis (HPO)", + "score": 9.880267708609392, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0003771", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000934", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0003549", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.880267708609392, + "jaccard_similarity": 0.3148148148148148, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.7636481080438524 + } + }, + "HP:0003834": { + "match_source": "HP:0003834", + "match_source_label": "Shoulder dislocation (HPO)", + "match_target": "HP:0003002", + "match_target_label": "Breast carcinoma (HPO)", + "score": 10.48204782739082, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0003834", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0003002", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000765", + "ancestor_label": "Abnormal thorax morphology (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.48204782739082, + "jaccard_similarity": 0.6341463414634146, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.5782071834483014 + } + }, + "HP:0004872": { + "match_source": "HP:0004872", + "match_source_label": "Incisional hernia (HPO)", + "match_target": "HP:0100578", + "match_target_label": "Lipoatrophy (HPO)", + "score": 9.880267708609392, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0004872", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0100578", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0003549", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.880267708609392, + "jaccard_similarity": 0.38461538461538464, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.9493852787096158 + } + }, + "HP:0004944": { + "match_source": "HP:0004944", + "match_source_label": "Dilatation of the cerebral artery (HPO)", + "match_target": "HP:0100659", + "match_target_label": "Abnormal cerebral vascular morphology (HPO)", + "score": 12.11867244793447, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0004944", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0100659", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0100659", + "ancestor_label": "Abnormal cerebral vascular morphology (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 12.11867244793447, + "jaccard_similarity": 0.6551724137931034, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.8177685993851953 + } + }, + "HP:0004947": { + "match_source": "HP:0004947", + "match_source_label": "Arteriovenous fistula (HPO)", + "match_target": "HP:0005177", + "match_target_label": "Premature arteriosclerosis (HPO)", + "score": 9.428674476515024, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0004947", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0005177", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0033353", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.428674476515024, + "jaccard_similarity": 0.6029411764705882, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.3843103995554302 + } + }, + "HP:0005294": { + "match_source": "HP:0005294", + "match_source_label": "Arterial dissection (HPO)", + "match_target": "HP:0004415", + "match_target_label": "Pulmonary artery stenosis (HPO)", + "score": 9.989389430989503, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0005294", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0004415", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011004", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.989389430989503, + "jaccard_similarity": 0.4, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.9989386614890916 + } + }, + "HP:0006243": { + "match_source": "HP:0006243", + "match_source_label": "Phalangeal dislocation (HPO)", + "match_target": "HP:0000934", + "match_target_label": "Chondrocalcinosis (HPO)", + "score": 9.004930281885281, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0006243", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000934", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0001367", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.004930281885281, + "jaccard_similarity": 0.23529411764705882, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.4556122853114004 + } + }, + "HP:0007495": { + "match_source": "HP:0007495", + "match_source_label": "Prematurely aged appearance (HPO)", + "match_target": "HP:0007495", + "match_target_label": "Prematurely aged appearance (HPO)", + "score": 14.418232729793377, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0007495", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0007495", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0007495", + "ancestor_label": "Prematurely aged appearance (HPO)", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 14.418232729793377, + "jaccard_similarity": 1, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.797134805322742 + } + }, + "HP:0009763": { + "match_source": "HP:0009763", + "match_source_label": "Limb pain (HPO)", + "match_target": "HP:0003419", + "match_target_label": "Low back pain (HPO)", + "score": 12.074278328576016, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0009763", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0003419", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0012531", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 12.074278328576016, + "jaccard_similarity": 0.5185185185185185, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.5021464607639357 + } + }, + "HP:0010749": { + "match_source": "HP:0010749", + "match_source_label": "Blepharochalasis (HPO)", + "match_target": "HP:0000320", + "match_target_label": "Bird-like facies (HPO)", + "score": 12.311317525876866, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0010749", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000320", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0001999", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 12.311317525876866, + "jaccard_similarity": 0.41237113402061853, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.2531826311761236 + } + }, + "HP:0010750": { + "match_source": "HP:0010750", + "match_source_label": "Dermatochalasis (HPO)", + "match_target": "HP:0007703", + "match_target_label": "Abnormality of retinal pigmentation (HPO)", + "score": 7.709281511796768, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0010750", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0007703", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000315", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.709281511796768, + "jaccard_similarity": 0.5480769230769231, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.0555484159025257 + } + }, + "HP:0010754": { + "match_source": "HP:0010754", + "match_source_label": "Abnormality of the temporomandibular joint (HPO)", + "match_target": "HP:0100649", + "match_target_label": "Neoplasm of the oral cavity (HPO)", + "score": 9.152888163272383, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0010754", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0100649", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0031816", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.152888163272383, + "jaccard_similarity": 0.41353383458646614, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 1.9455150833902846 + } + }, + "HP:0012378": { + "match_source": "HP:0012378", + "match_source_label": "Fatigue (HPO)", + "match_target": "HP:0003419", + "match_target_label": "Low back pain (HPO)", + "score": 11.324256581584363, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0012378", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0003419", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0025142", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 11.324256581584363, + "jaccard_similarity": 0.36, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.0190919665459446 + } + }, + "HP:0012450": { + "match_source": "HP:0012450", + "match_source_label": "Chronic constipation (HPO)", + "match_target": "HP:0100833", + "match_target_label": "Neoplasm of the small intestine (HPO)", + "score": 7.826350815132431, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0012450", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0100833", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0025031", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 7.826350815132431, + "jaccard_similarity": 0.5217391304347826, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.0207210269517035 + } + }, + "HP:0025014": { + "match_source": "HP:0025014", + "match_source_label": "Subcutaneous spheroids (HPO)", + "match_target": "HP:0008065", + "match_target_label": "Aplasia/Hypoplasia of the skin (HPO)", + "score": 10.72635502515571, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0025014", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0008065", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011355", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.72635502515571, + "jaccard_similarity": 0.8333333333333334, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.9897540346372575 + } + }, + "HP:0025019": { + "match_source": "HP:0025019", + "match_source_label": "Arterial rupture (HPO)", + "match_target": "HP:0000822", + "match_target_label": "Hypertension (HPO)", + "score": 9.47121402147955, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0025019", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0000822", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011025", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 9.47121402147955, + "jaccard_similarity": 0.6557377049180327, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.4921139912196013 + } + }, + "HP:0025509": { + "match_source": "HP:0025509", + "match_source_label": "Piezogenic pedal papules (HPO)", + "match_target": "HP:0200042", + "match_target_label": "Skin ulcer (HPO)", + "score": 10.72635502515571, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0025509", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0200042", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0011355", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 10.72635502515571, + "jaccard_similarity": 0.9210526315789473, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 3.143173161499336 + } + }, + "HP:0030009": { + "match_source": "HP:0030009", + "match_source_label": "Cervical insufficiency (HPO)", + "match_target": "HP:0100615", + "match_target_label": "Ovarian neoplasm (HPO)", + "score": 11.350488123157543, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0030009", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0100615", + "object_label": null, + "object_source": null, + "ancestor_id": "HP:0000008", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 11.350488123157543, + "jaccard_similarity": 0.6301369863013698, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.674390094764783 + } + }, + "HP:0031364": { + "match_source": "HP:0031364", + "match_source_label": "Ecchymosis (HPO)", + "match_target": "HP:0007618", + "match_target_label": "Subcutaneous calcification (HPO)", + "score": 14.533709947213314, + "match_subsumer": null, + "match_subsumer_label": null, + "similarity": { + "subject_id": "HP:0031364", + "subject_label": null, + "subject_source": null, + "object_id": "HP:0007618", + "object_label": null, + "object_source": null, + "ancestor_id": "UBERON:0011818", + "ancestor_label": "", + "ancestor_source": null, + "object_information_content": null, + "subject_information_content": null, + "ancestor_information_content": 14.533709947213314, + "jaccard_similarity": 0.4222222222222222, + "cosine_similarity": null, + "dice_similarity": null, + "phenodigm_score": 2.47718697539076 + } + }, + "HP:0031653": { + "match_source": "HP:0031653", + "match_source_label": "Abnormal heart valve physiology (HPO)", + "match_target": "HP:0001635", + "match_target_label": "Congestive heart failure (HPO)", + "score": 9.47121402147955, "match_subsumer": null, "match_subsumer_label": null, "similarity": { - "subject_id": "HP:0004325", + "subject_id": "HP:0031653", "subject_label": null, "subject_source": null, - "object_id": "MP:0010771", + "object_id": "HP:0001635", "object_label": null, "object_source": null, - "ancestor_id": "UPHENO:0001003", + "ancestor_id": "HP:0011025", "ancestor_label": "", "ancestor_source": null, "object_information_content": null, "subject_information_content": null, - "ancestor_information_content": 1.4431977534690428, - "jaccard_similarity": 0.3333333333333333, + "ancestor_information_content": 9.47121402147955, + "jaccard_similarity": 0.3972602739726027, "cosine_similarity": null, "dice_similarity": null, - "phenodigm_score": 0.6935891563620457 + "phenodigm_score": 1.9397260314348834 } } }, - "average_score": 1.4431977534690428, - "best_score": 1.4431977534690428, + "average_score": 9.923734289544303, + "best_score": 17.11867244793447, "metric": "ancestor_information_content" } diff --git a/frontend/package.json b/frontend/package.json index 94de3413f..0c1bf1f14 100644 --- a/frontend/package.json +++ b/frontend/package.json @@ -25,7 +25,6 @@ "@vueuse/core": "^10.4.1", "apexcharts": "^3.43.0", "body-scroll-lock": "4.0.0-beta.0", - "dom-to-image": "^2.6.0", "lodash": "^4.17.21", "micromark": "^4.0.0", "normalize.css": "^8.0.1", diff --git a/frontend/src/api/index.ts b/frontend/src/api/index.ts index 34cf93fec..f12151c7f 100644 --- a/frontend/src/api/index.ts +++ b/frontend/src/api/index.ts @@ -1,4 +1,4 @@ -import { groupLog } from "@/util/debug"; +import { groupLog, sleep } from "@/util/debug"; import { getUrl } from "@/util/url"; /** base biolink api url */ @@ -89,6 +89,9 @@ export const request = async ( paramsObject.append(key, String(value)); } + /** artificial delay */ + await sleep(10); + /** sort params for consistency */ paramsObject.sort(); diff --git a/frontend/src/api/model.ts b/frontend/src/api/model.ts index 34b656aeb..237becece 100644 --- a/frontend/src/api/model.ts +++ b/frontend/src/api/model.ts @@ -63,8 +63,6 @@ export interface Association { has_evidence?: string[], /** List of ExpandedCuries with id and url for evidence */ has_evidence_links?: ExpandedCurie[], - /** A concatenation of fields used to group associations with the same essential/defining properties */ - grouping_key?: string, provided_by?: string, /** A link to the docs for the knowledge source that provided the node/edge. */ provided_by_link?: ExpandedCurie, @@ -77,16 +75,6 @@ export interface Association { sex_qualifier?: string, stage_qualifier?: string, /** The name of the frequency_qualifier entity */ - qualifiers_label?: string, - /** The namespace/prefix of the frequency_qualifier entity */ - qualifiers_namespace?: string, - /** The category of the frequency_qualifier entity */ - qualifiers_category?: string, - /** Field containing frequency_qualifier id and the ids of all of it's ancestors */ - qualifiers_closure?: string[], - /** Field containing frequency_qualifier name and the names of all of it's ancestors */ - qualifiers_closure_label?: string[], - /** The name of the frequency_qualifier entity */ frequency_qualifier_label?: string, /** The namespace/prefix of the frequency_qualifier entity */ frequency_qualifier_namespace?: string, @@ -235,8 +223,6 @@ export interface DirectionalAssociation extends Association { has_evidence?: string[], /** List of ExpandedCuries with id and url for evidence */ has_evidence_links?: ExpandedCurie[], - /** A concatenation of fields used to group associations with the same essential/defining properties */ - grouping_key?: string, provided_by?: string, /** A link to the docs for the knowledge source that provided the node/edge. */ provided_by_link?: ExpandedCurie, @@ -249,16 +235,6 @@ export interface DirectionalAssociation extends Association { sex_qualifier?: string, stage_qualifier?: string, /** The name of the frequency_qualifier entity */ - qualifiers_label?: string, - /** The namespace/prefix of the frequency_qualifier entity */ - qualifiers_namespace?: string, - /** The category of the frequency_qualifier entity */ - qualifiers_category?: string, - /** Field containing frequency_qualifier id and the ids of all of it's ancestors */ - qualifiers_closure?: string[], - /** Field containing frequency_qualifier name and the names of all of it's ancestors */ - qualifiers_closure_label?: string[], - /** The name of the frequency_qualifier entity */ frequency_qualifier_label?: string, /** The namespace/prefix of the frequency_qualifier entity */ frequency_qualifier_namespace?: string, @@ -324,8 +300,6 @@ export interface Entity { in_taxon_label?: string, symbol?: string, synonym?: string[], - /** The URI of the entity */ - uri?: string, }; export interface EntityResults extends Results { @@ -363,19 +337,6 @@ export interface HistoBin extends FacetValue { /** count of documents */ count?: number, }; -/** - * A minimal class to hold a SSSOM mapping - */ -export interface Mapping { - subject_id: string, - /** The name of the subject entity */ - subject_label?: string, - predicate_id: string, - object_id: string, - /** The name of the object entity */ - object_label?: string, - mapping_justification?: string, -}; export interface MultiEntityAssociationResults extends Results { id: string, @@ -417,8 +378,6 @@ export interface Node extends Entity { provided_by?: string, symbol?: string, synonym?: string[], - /** The URI of the entity */ - uri?: string, }; export interface NodeHierarchy { @@ -453,8 +412,6 @@ export interface SearchResult extends Entity { in_taxon_label?: string, symbol?: string, synonym?: string[], - /** The URI of the entity */ - uri?: string, }; export interface SearchResults extends Results { @@ -480,12 +437,14 @@ export interface PairwiseSimilarity { * A simple pairwise similarity between two atomic concepts/terms */ export interface TermPairwiseSimilarity extends PairwiseSimilarity { + /** The first of the two entities being compared */ subject_id: string, /** The name of the subject entity */ subject_label?: string, /** the source for the first entity */ subject_source?: string, - object_id: string, + /** The second of the two entities being compared */ + object_id?: string, /** The name of the object entity */ object_label?: string, /** the source for the second entity */ diff --git a/frontend/src/components/AppDetail.vue b/frontend/src/components/AppDetail.vue index 2abfd8a72..125e891e3 100644 --- a/frontend/src/components/AppDetail.vue +++ b/frontend/src/components/AppDetail.vue @@ -16,7 +16,7 @@ {{ title }} - {{ count }} + {{ count.toLocaleString() }} diff --git a/frontend/src/components/AppModal.vue b/frontend/src/components/AppModal.vue index f51924d99..49f9ea413 100644 --- a/frontend/src/components/AppModal.vue +++ b/frontend/src/components/AppModal.vue @@ -87,7 +87,7 @@ const modal = ref(); /** after state change */ onUpdated(() => { /** rest of app besides modal */ - const app = document?.querySelector("#app"); + const app = document.querySelector("#app"); /** if modal just opened */ if (props.modelValue) { @@ -107,11 +107,11 @@ onUpdated(() => { /** before state change */ onBeforeUpdate(async () => { /** rest of app besides modal */ - const app = document?.querySelector("#app"); + const app = document.querySelector("#app"); /** if modal about to be opened */ if (props.modelValue) { - originalFocus.value = document?.activeElement as HTMLElement; + originalFocus.value = document.activeElement as HTMLElement; } else { /** if modal about to be closed */ /** show for screen readers */ diff --git a/frontend/src/components/AppPlaceholder.vue b/frontend/src/components/AppPlaceholder.vue index 97436b8f4..4c52c29d2 100644 --- a/frontend/src/components/AppPlaceholder.vue +++ b/frontend/src/components/AppPlaceholder.vue @@ -1,5 +1,5 @@ diff --git a/frontend/src/components/TheTableOfContents.vue b/frontend/src/components/TheTableOfContents.vue index bc2912676..301f59cd2 100644 --- a/frontend/src/components/TheTableOfContents.vue +++ b/frontend/src/components/TheTableOfContents.vue @@ -104,8 +104,8 @@ async function updatePosition() { await nextTick(); /** get dimensions of header and "sub-header" (e.g. first section on node page) */ - const headerEl = document?.querySelector("header"); - const subHeaderEl = document?.querySelector("main > section:first-child"); + const headerEl = document.querySelector("header"); + const subHeaderEl = document.querySelector("main > section:first-child"); if (!headerEl || !subHeaderEl) return; const header = headerEl.getBoundingClientRect(); const subHeader = subHeaderEl.getBoundingClientRect(); @@ -130,7 +130,7 @@ async function updatePosition() { function updateEntries() { entries.value = Array.from( /** get all headings except top level one */ - document?.querySelectorAll("h2[id], h3[id]") || [], + document.querySelectorAll("h2[id], h3[id]") || [], ).map((element) => /** get relevant props from heading */ ({ @@ -166,7 +166,7 @@ onMounted(updatePosition); useEventListener(window, "scroll", updatePosition); useEventListener(window, "resize", updatePosition); useMutationObserver( - document?.body, + document.body, () => { updatePosition(); updateEntries(); diff --git a/frontend/src/global/components.ts b/frontend/src/global/components.ts index 5dfadf5e1..95fbeed84 100644 --- a/frontend/src/global/components.ts +++ b/frontend/src/global/components.ts @@ -5,7 +5,6 @@ import AppHeading from "@/components/AppHeading.vue"; import AppIcon from "@/components/AppIcon.vue"; import AppLink from "@/components/AppLink.vue"; import AppMarkdown from "@/components/AppMarkdown.vue"; -import AppPlaceholder from "@/components/AppPlaceholder.vue"; import AppSection from "@/components/AppSection.vue"; import AppStatus from "@/components/AppStatus.vue"; import AppTile from "@/components/AppTile.vue"; @@ -22,7 +21,6 @@ const globalComponents = { AppIcon, AppLink, AppMarkdown, - AppPlaceholder, AppSection, AppStatus, AppTile, @@ -43,7 +41,6 @@ declare module "@vue/runtime-core" { AppIcon: typeof AppIcon; AppLink: typeof AppLink; AppMarkdown: typeof AppMarkdown; - AppPlaceholder: typeof AppPlaceholder; AppSection: typeof AppSection; AppStatus: typeof AppStatus; AppTile: typeof AppTile; diff --git a/frontend/src/global/styles.scss b/frontend/src/global/styles.scss index 47613b9a3..9901cd63e 100644 --- a/frontend/src/global/styles.scss +++ b/frontend/src/global/styles.scss @@ -56,7 +56,7 @@ h3 { padding: 10px 0; font-weight: 500; font-size: 1.1rem; - text-align: left; + text-align: center; } /** elements */ @@ -224,7 +224,7 @@ strong { .tippy-content { display: flex; - flex-wrap: wrap; + flex-direction: column; width: 100%; padding: 0 !important; gap: 10px; @@ -238,11 +238,6 @@ strong { } } -/** useless tippy wrapper span that sometimes appears */ -.tippy-content > span { - display: contents !important; /** effectively take out of dom */ -} - /** for spans of text (not clickable, not links, not buttons) with tooltips */ .tooltip { text-decoration: underline; @@ -253,10 +248,10 @@ strong { .mini-table { display: grid; - grid-template-columns: auto auto; + grid-template-columns: max-content auto; align-items: center; justify-items: flex-start; - gap: 5px 15px; + gap: 5px 20px; text-align: left; } diff --git a/frontend/src/global/tooltip.ts b/frontend/src/global/tooltip.ts index f6e2c35dc..7bfe8bee0 100644 --- a/frontend/src/global/tooltip.ts +++ b/frontend/src/global/tooltip.ts @@ -21,9 +21,14 @@ const update = (instance: Instance): void => { instance.reference.setAttribute("data-tooltip", "true"); }; -/** cancel show if no content to show */ -const onShow = (instance: Instance): boolean => - !!String(instance.props.content).trim(); +const onShow = (instance: Instance): boolean => { + const content = instance.props.content; + // https://github.com/KABBOUCHI/vue-tippy/issues/303 + if (content instanceof Element && instance.reference instanceof SVGElement) + instance.setContent(content.innerHTML); + /** cancel show if no content to show */ + return !!String(content).trim(); +}; /** return false to inspect popup for debugging */ const onHide = (): boolean => true; diff --git a/frontend/src/global/variables.scss b/frontend/src/global/variables.scss index 8ec35a68b..d0e70394c 100644 --- a/frontend/src/global/variables.scss +++ b/frontend/src/global/variables.scss @@ -5,7 +5,7 @@ $theme-light: hsl(185, 75%, 80%); $white: #ffffff; $off-white: #fafafa; $light-gray: #eeeeee; -$gray: #b0b0b0; +$gray: #a0a0a0; $dark-gray: #808080; $off-black: #404040; $black: #000000; @@ -19,9 +19,6 @@ $fast: 0.2s ease; $sans: "Poppins", sans-serif; $mono: "Courier Prime", monospace; -/** font sizes */ -/** 0.9rem to 2.0rem in 0.1rem increments */ - /** line spacing */ $spacing: 1.5; diff --git a/frontend/src/pages/PageTestbed.vue b/frontend/src/pages/PageTestbed.vue index 2cc156c6c..940717e0f 100644 --- a/frontend/src/pages/PageTestbed.vue +++ b/frontend/src/pages/PageTestbed.vue @@ -195,7 +195,8 @@ useEventListener( (event: MessageEvent<{ width: number; height: number }>) => { const iframe = document.querySelector("iframe"); if (!iframe) return; - iframe.style.height = event.data.height + 20 + "px"; + iframe.style.maxWidth = event.data.width + "px"; + iframe.style.maxHeight = event.data.height + "px"; }, ); @@ -357,6 +358,7 @@ const log = console.info; diff --git a/frontend/src/pages/explore/TabPhenotypeExplorer.vue b/frontend/src/pages/explore/TabPhenotypeExplorer.vue index 068d046cb..339bf4c25 100644 --- a/frontend/src/pages/explore/TabPhenotypeExplorer.vue +++ b/frontend/src/pages/explore/TabPhenotypeExplorer.vue @@ -58,58 +58,58 @@ @click="runAnalysis" /> This feature is still being worked on. Check back soon!This feature is still under development. Check back soon for + more! Results +

Similarity comparison between pairs of phenotypes.

+ Running analysis Error running analysis - +