The PFR will provide a framework to fundamentally advance and simplify computational approaches for interpreting human genome variation. We are - the creators of the Human Phenotype Ontology which has been the + the creators of the Human Phenotype Ontology (HPO), which has been the cornerstone of our pioneering work in data integration. We will leverage this to align phenotype ontologies and clinical terminologies, bringing major model species and clinical domains into the PFR, which we will - refine through continual community partnership. We propose the following - interlinked approaches that will provide a dynamic suite of - community-developed knowledge resources to revolutionize variant - interpretation applications and drive precision medicine. + refine through continual community partnership. The following interlinked + approaches will provide a dynamic suite of community-developed knowledge + resources to revolutionize variant interpretation applications and drive + precision medicine.
@@ -83,7 +83,7 @@ />