DAA Critique Discussion

[tpq]

Hey Mike,

This popped up on my GitHub feed. It's so cool to see a manuscript being written in the open! I am a big fan of your "Consistent and Correctable Bias" paper from a couple years back, and appreciate your commitment to truly open science.

Like you, I've come to doubt the utility of differential abundance analysis. We recently wrote up our perspective that challenges DAA, and offer some possible (ratio-based) alternatives. I wanted to link you to it because I think there may be some synergy between our perspectives, and it could be fun to start a discussion.