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So far we ran optimize-matrices-GA on matrices resulting from peak-motifs | matrix-clustering | trimming.
With matrix optimization, it is not sure that we need the clustering step. Starting from the peak-motifs discovered motifs would give more traceability on the source of the motifs retained at the end of the optimisation, and possibly tell us if some algorithms (oligo-analysis, dyad-analysis, position-analysis) give generally better results, or if this depends on the TF/dataset.
The text was updated successfully, but these errors were encountered:
jvanheld
changed the title
optimize-matrix: start from peak-motifs matrices rather than from matrix-clustering results
optimize primary peak-motifs discovered matrices rather than clustered matrices
Aug 28, 2024
So far we ran
optimize-matrices-GA
on matrices resulting from peak-motifs | matrix-clustering | trimming.With matrix optimization, it is not sure that we need the clustering step. Starting from the peak-motifs discovered motifs would give more traceability on the source of the motifs retained at the end of the optimisation, and possibly tell us if some algorithms (oligo-analysis, dyad-analysis, position-analysis) give generally better results, or if this depends on the TF/dataset.
The text was updated successfully, but these errors were encountered: