Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

optimize primary peak-motifs discovered matrices rather than clustered matrices #15

Open
Tracked by #12
jvanheld opened this issue Aug 28, 2024 · 0 comments
Open
Tracked by #12
Assignees

Comments

@jvanheld
Copy link
Owner

jvanheld commented Aug 28, 2024

So far we ran optimize-matrices-GA on matrices resulting from peak-motifs | matrix-clustering | trimming.

With matrix optimization, it is not sure that we need the clustering step. Starting from the peak-motifs discovered motifs would give more traceability on the source of the motifs retained at the end of the optimisation, and possibly tell us if some algorithms (oligo-analysis, dyad-analysis, position-analysis) give generally better results, or if this depends on the TF/dataset.

@jvanheld jvanheld mentioned this issue Aug 28, 2024
12 tasks
@jvanheld jvanheld changed the title optimize-matrix: start from peak-motifs matrices rather than from matrix-clustering results optimize primary peak-motifs discovered matrices rather than clustered matrices Aug 28, 2024
@jvanheld jvanheld self-assigned this Aug 28, 2024
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

1 participant