From 3f7004101bec5b270e25bbf66a7af8b6d843c73d Mon Sep 17 00:00:00 2001 From: PlushZ Date: Tue, 7 May 2024 13:58:37 +0200 Subject: [PATCH 01/10] add -s option for scoresets vis --- README.md | 7 + .../example_mave_data/input/MaveBindRBD.csv | 8041 +++++++++++++++++ .../example_mave_data/input/MaveExpRBD.csv | 8041 +++++++++++++++++ .../example_mave_data/input/SARS-CoV-2.gff3 | 65 + .../example_mave_data/input/sample-01.vcf | 178 + .../example_mave_data/input/sample-02.vcf | 245 + .../example_mave_data/input/sample-03.vcf | 104 + .../example_mave_data/input/sample-04.vcf | 125 + .../example_mave_data/input/sample-05.vcf | 160 + .../example_mave_data/input/sample-06.vcf | 156 + .../example_mave_data/input/sample-07.vcf | 136 + .../example_mave_data/input/sample-08.vcf | 89 + .../example_mave_data/input/sample-09.vcf | 218 + .../example_mave_data/input/sample-10.vcf | 196 + .../example_mave_data/input/sample-11.vcf | 30 + .../example_mave_data/input/sample-12.vcf | 94 + .../output/virHEAT_plot_12samples_1score.pdf | Bin 0 -> 43566 bytes .../output/virHEAT_plot_12samples_2scores.pdf | Bin 0 -> 45685 bytes .../virHEAT_plot_12samples_2scores_zoom.pdf | Bin 0 -> 30475 bytes .../output/virHEAT_plot_3samples_4scores.pdf | Bin 0 -> 31878 bytes .../output/virHEAT_plot_3ssamples2scores.pdf | Bin 0 -> 28625 bytes .../virHEAT_plot_many-samples_4scores.pdf | Bin 0 -> 89896 bytes .../virHEAT_plot_many_samples_6scores.pdf | Bin 0 -> 397992 bytes virheat/__init__.py | 2 +- virheat/command.py | 73 +- virheat/scripts/data_prep.py | 43 +- virheat/scripts/plotting.py | 79 +- 27 files changed, 18065 insertions(+), 17 deletions(-) create mode 100644 example_data/example_mave_data/input/MaveBindRBD.csv create mode 100644 example_data/example_mave_data/input/MaveExpRBD.csv create mode 100644 example_data/example_mave_data/input/SARS-CoV-2.gff3 create mode 100644 example_data/example_mave_data/input/sample-01.vcf create mode 100644 example_data/example_mave_data/input/sample-02.vcf create mode 100644 example_data/example_mave_data/input/sample-03.vcf create mode 100644 example_data/example_mave_data/input/sample-04.vcf create mode 100644 example_data/example_mave_data/input/sample-05.vcf create mode 100644 example_data/example_mave_data/input/sample-06.vcf create mode 100644 example_data/example_mave_data/input/sample-07.vcf create mode 100644 example_data/example_mave_data/input/sample-08.vcf create mode 100644 example_data/example_mave_data/input/sample-09.vcf create mode 100644 example_data/example_mave_data/input/sample-10.vcf create mode 100644 example_data/example_mave_data/input/sample-11.vcf create mode 100644 example_data/example_mave_data/input/sample-12.vcf create mode 100644 example_data/example_mave_data/output/virHEAT_plot_12samples_1score.pdf create mode 100644 example_data/example_mave_data/output/virHEAT_plot_12samples_2scores.pdf create mode 100644 example_data/example_mave_data/output/virHEAT_plot_12samples_2scores_zoom.pdf create mode 100644 example_data/example_mave_data/output/virHEAT_plot_3samples_4scores.pdf create mode 100644 example_data/example_mave_data/output/virHEAT_plot_3ssamples2scores.pdf create mode 100644 example_data/example_mave_data/output/virHEAT_plot_many-samples_4scores.pdf create mode 100644 example_data/example_mave_data/output/virHEAT_plot_many_samples_6scores.pdf diff --git a/README.md b/README.md index 222eb9f..8d6091c 100644 --- a/README.md +++ b/README.md @@ -77,6 +77,9 @@ options: restrict the plot to a specific genomic region. --sort, --no-sort sort sample names alphanumerically (default: False) --min-cov 20 display mutations covered at least x time (only if per base cov tsv files are provided) + -s scores_file pos_col score_col score_name, --scores scores_file pos_col score_col score_name + specify scores to be added to the plot by providing a CSV file containing scores, along with its column for amino-acid positions, its column for scores, and descriptive score names (e.g., expression, binding, antibody escape, etc.). + This option can be used multiple times to include multiple sets of scores. -v, --version show program's version number and exit ``` @@ -84,6 +87,10 @@ You need to either provide the length of your reference genome or if you want to Additionally, you can also analyse if mutations are sufficiently covered and display non-covered cells in grey. For that first create a per base coverage tsv files for each bam file with [Qualimap](http://qualimap.conesalab.org/) and provide it in the same folder as the vcf files. Give them the same name as your vcf files. +Moreover, there is an option to include visualizations of additional scores (e.g., MAVE scores for binding affinity, expression level, antibody escape, etc.) mapped to mutations on the heatmap. To utilize this feature, use the -s or --scores +argument, and provide the following arguments: 1) path to the CSV file containing scores; 2) the name of the column in this file containing mutation positions in classic notation (e.g., T430Y); 3) the name of the column in this file containing the +scores themselves; 4) a descriptive score name that will be used as labels in the plot. Multiple score sets can be included simultaneously by repeating the -s or --scores option with different arguments. For example input and possible output data, +please refer to the files located in the [example_data/example_mave_data](https://github.com/{repo}/tree/main/example_data/example_mave_data) folder. --- **Important disclaimer:** diff --git a/example_data/example_mave_data/input/MaveBindRBD.csv b/example_data/example_mave_data/input/MaveBindRBD.csv new file mode 100644 index 0000000..11b58cb --- /dev/null +++ b/example_data/example_mave_data/input/MaveBindRBD.csv @@ -0,0 +1,8041 @@ +accession,hgvs_nt,hgvs_splice,hgvs_pro,score,average,library,AA +urn:mavedb:00000044-a-1#7954,NA,NA,p.Lys199Val,0.09,0.07,2,K529V +urn:mavedb:00000044-a-1#7955,NA,NA,p.Lys199Trp,-0.02,0,1,K529W +urn:mavedb:00000044-a-1#7956,NA,NA,p.Lys199Trp,0.01,0,2,K529W +urn:mavedb:00000044-a-1#7957,NA,NA,p.Lys199Tyr,0,0,1,K529Y +urn:mavedb:00000044-a-1#7958,NA,NA,p.Lys199Tyr,0.01,0,2,K529Y +urn:mavedb:00000044-a-1#7961,NA,NA,p.Ser200Ala,-0.01,0,1,S530A +urn:mavedb:00000044-a-1#7962,NA,NA,p.Ser200Ala,0,0,2,S530A 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+urn:mavedb:00000044-a-1#5154,NA,NA,p.Ser129Val,-0.03,0,2,S459V +urn:mavedb:00000044-a-1#5155,NA,NA,p.Ser129Trp,-0.17,-0.21,1,S459W +urn:mavedb:00000044-a-1#5156,NA,NA,p.Ser129Trp,-0.24,-0.21,2,S459W +urn:mavedb:00000044-a-1#5157,NA,NA,p.Ser129Tyr,-0.07,-0.09,1,S459Y +urn:mavedb:00000044-a-1#5158,NA,NA,p.Ser129Tyr,-0.11,-0.09,2,S459Y +urn:mavedb:00000044-a-1#5159,NA,NA,p.Ser129*,NA,NA,1,S459 +urn:mavedb:00000044-a-1#5160,NA,NA,p.Ser129*,NA,NA,2,S459 +urn:mavedb:00000044-a-1#5161,NA,NA,p.Asn130Ala,0.04,0.03,1,N460A +urn:mavedb:00000044-a-1#5162,NA,NA,p.Asn130Ala,0.02,0.03,2,N460A +urn:mavedb:00000044-a-1#5163,NA,NA,p.Asn130Cys,-0.06,-0.07,1,N460C +urn:mavedb:00000044-a-1#5164,NA,NA,p.Asn130Cys,-0.08,-0.07,2,N460C +urn:mavedb:00000044-a-1#5165,NA,NA,p.Asn130Asp,-0.06,-0.06,1,N460D +urn:mavedb:00000044-a-1#5166,NA,NA,p.Asn130Asp,-0.06,-0.06,2,N460D +urn:mavedb:00000044-a-1#5167,NA,NA,p.Asn130Glu,0,-0.03,1,N460E +urn:mavedb:00000044-a-1#5168,NA,NA,p.Asn130Glu,-0.06,-0.03,2,N460E +urn:mavedb:00000044-a-1#5169,NA,NA,p.Asn130Phe,-0.08,-0.09,1,N460F +urn:mavedb:00000044-a-1#5170,NA,NA,p.Asn130Phe,-0.09,-0.09,2,N460F +urn:mavedb:00000044-a-1#5171,NA,NA,p.Asn130Gly,-0.18,-0.09,1,N460G +urn:mavedb:00000044-a-1#5172,NA,NA,p.Asn130Gly,0.01,-0.09,2,N460G +urn:mavedb:00000044-a-1#5173,NA,NA,p.Asn130His,0.05,0.02,1,N460H +urn:mavedb:00000044-a-1#5174,NA,NA,p.Asn130His,-0.01,0.02,2,N460H +urn:mavedb:00000044-a-1#5175,NA,NA,p.Asn130Ile,-0.03,0.02,1,N460I +urn:mavedb:00000044-a-1#5176,NA,NA,p.Asn130Ile,0.06,0.02,2,N460I +urn:mavedb:00000044-a-1#5177,NA,NA,p.Asn130Lys,0.07,0.09,1,N460K +urn:mavedb:00000044-a-1#5178,NA,NA,p.Asn130Lys,0.1,0.09,2,N460K +urn:mavedb:00000044-a-1#5179,NA,NA,p.Asn130Leu,-0.04,-0.05,1,N460L +urn:mavedb:00000044-a-1#5180,NA,NA,p.Asn130Leu,-0.06,-0.05,2,N460L +urn:mavedb:00000044-a-1#5181,NA,NA,p.Asn130Met,0.01,-0.04,1,N460M +urn:mavedb:00000044-a-1#5182,NA,NA,p.Asn130Met,-0.08,-0.04,2,N460M +urn:mavedb:00000044-a-1#5183,NA,NA,p.Asn130Pro,-0.03,-0.01,1,N460P +urn:mavedb:00000044-a-1#5184,NA,NA,p.Asn130Pro,0.01,-0.01,2,N460P +urn:mavedb:00000044-a-1#5185,NA,NA,p.Asn130Gln,0.02,0.02,1,N460Q +urn:mavedb:00000044-a-1#5186,NA,NA,p.Asn130Gln,0.02,0.02,2,N460Q +urn:mavedb:00000044-a-1#5187,NA,NA,p.Asn130Arg,0.08,0.06,1,N460R +urn:mavedb:00000044-a-1#5188,NA,NA,p.Asn130Arg,0.04,0.06,2,N460R +urn:mavedb:00000044-a-1#5189,NA,NA,p.Asn130Ser,-0.14,-0.08,1,N460S +urn:mavedb:00000044-a-1#5190,NA,NA,p.Asn130Ser,-0.01,-0.08,2,N460S +urn:mavedb:00000044-a-1#5191,NA,NA,p.Asn130Thr,-0.1,-0.16,1,N460T +urn:mavedb:00000044-a-1#5192,NA,NA,p.Asn130Thr,-0.22,-0.16,2,N460T +urn:mavedb:00000044-a-1#5193,NA,NA,p.Asn130Val,0.03,0.05,1,N460V +urn:mavedb:00000044-a-1#5194,NA,NA,p.Asn130Val,0.06,0.05,2,N460V +urn:mavedb:00000044-a-1#5195,NA,NA,p.Asn130Trp,-0.2,-0.29,1,N460W +urn:mavedb:00000044-a-1#5196,NA,NA,p.Asn130Trp,-0.37,-0.29,2,N460W +urn:mavedb:00000044-a-1#5197,NA,NA,p.Asn130Tyr,-0.02,-0.04,1,N460Y +urn:mavedb:00000044-a-1#5198,NA,NA,p.Asn130Tyr,-0.06,-0.04,2,N460Y +urn:mavedb:00000044-a-1#5199,NA,NA,p.Asn130*,NA,NA,1,N460 +urn:mavedb:00000044-a-1#5200,NA,NA,p.Asn130*,NA,NA,2,N460 +urn:mavedb:00000044-a-1#5201,NA,NA,p.Leu131Ala,-1.01,-1,1,L461A +urn:mavedb:00000044-a-1#4798,NA,NA,p.Asn120Tyr,-0.15,-0.13,2,N450Y +urn:mavedb:00000044-a-1#4799,NA,NA,p.Asn120*,NA,NA,1,N450 +urn:mavedb:00000044-a-1#4800,NA,NA,p.Asn120*,NA,NA,2,N450 +urn:mavedb:00000044-a-1#4801,NA,NA,p.Tyr121Ala,-0.76,-0.84,1,Y451A +urn:mavedb:00000044-a-1#4802,NA,NA,p.Tyr121Ala,-0.93,-0.84,2,Y451A +urn:mavedb:00000044-a-1#4803,NA,NA,p.Tyr121Cys,-0.62,-0.64,1,Y451C +urn:mavedb:00000044-a-1#4804,NA,NA,p.Tyr121Cys,-0.65,-0.64,2,Y451C +urn:mavedb:00000044-a-1#4805,NA,NA,p.Tyr121Asp,-2.43,-2.54,1,Y451D +urn:mavedb:00000044-a-1#4806,NA,NA,p.Tyr121Asp,-2.65,-2.54,2,Y451D +urn:mavedb:00000044-a-1#4807,NA,NA,p.Tyr121Glu,-1.25,-1.46,1,Y451E +urn:mavedb:00000044-a-1#4808,NA,NA,p.Tyr121Glu,-1.68,-1.46,2,Y451E +urn:mavedb:00000044-a-1#4809,NA,NA,p.Tyr121Phe,-0.04,-0.09,1,Y451F +urn:mavedb:00000044-a-1#4810,NA,NA,p.Tyr121Phe,-0.14,-0.09,2,Y451F +urn:mavedb:00000044-a-1#4811,NA,NA,p.Tyr121Gly,-2.38,-2.37,1,Y451G +urn:mavedb:00000044-a-1#4812,NA,NA,p.Tyr121Gly,-2.35,-2.37,2,Y451G +urn:mavedb:00000044-a-1#4813,NA,NA,p.Tyr121His,-0.08,-0.11,1,Y451H +urn:mavedb:00000044-a-1#4814,NA,NA,p.Tyr121His,-0.15,-0.11,2,Y451H +urn:mavedb:00000044-a-1#4815,NA,NA,p.Tyr121Ile,-0.41,-0.44,1,Y451I +urn:mavedb:00000044-a-1#4816,NA,NA,p.Tyr121Ile,-0.47,-0.44,2,Y451I +urn:mavedb:00000044-a-1#4817,NA,NA,p.Tyr121Lys,-0.62,-0.7,1,Y451K +urn:mavedb:00000044-a-1#4818,NA,NA,p.Tyr121Lys,-0.77,-0.7,2,Y451K +urn:mavedb:00000044-a-1#4819,NA,NA,p.Tyr121Leu,-0.26,-0.29,1,Y451L +urn:mavedb:00000044-a-1#4820,NA,NA,p.Tyr121Leu,-0.32,-0.29,2,Y451L +urn:mavedb:00000044-a-1#4821,NA,NA,p.Tyr121Met,-0.28,-0.34,1,Y451M +urn:mavedb:00000044-a-1#4822,NA,NA,p.Tyr121Met,-0.4,-0.34,2,Y451M +urn:mavedb:00000044-a-1#4823,NA,NA,p.Tyr121Asn,-0.5,-0.58,1,Y451N +urn:mavedb:00000044-a-1#4824,NA,NA,p.Tyr121Asn,-0.66,-0.58,2,Y451N +urn:mavedb:00000044-a-1#4825,NA,NA,p.Tyr121Pro,-1.17,-1.25,1,Y451P +urn:mavedb:00000044-a-1#4826,NA,NA,p.Tyr121Pro,-1.33,-1.25,2,Y451P +urn:mavedb:00000044-a-1#4827,NA,NA,p.Tyr121Gln,-0.05,-0.13,1,Y451Q +urn:mavedb:00000044-a-1#4828,NA,NA,p.Tyr121Gln,-0.2,-0.13,2,Y451Q +urn:mavedb:00000044-a-1#4829,NA,NA,p.Tyr121Arg,-1.12,-1.23,1,Y451R +urn:mavedb:00000044-a-1#4830,NA,NA,p.Tyr121Arg,-1.34,-1.23,2,Y451R +urn:mavedb:00000044-a-1#4831,NA,NA,p.Tyr121Ser,-0.75,-0.83,1,Y451S +urn:mavedb:00000044-a-1#4832,NA,NA,p.Tyr121Ser,-0.91,-0.83,2,Y451S +urn:mavedb:00000044-a-1#4833,NA,NA,p.Tyr121Thr,-1.23,-1.24,1,Y451T +urn:mavedb:00000044-a-1#4834,NA,NA,p.Tyr121Thr,-1.24,-1.24,2,Y451T +urn:mavedb:00000044-a-1#4835,NA,NA,p.Tyr121Val,-0.74,-0.79,1,Y451V +urn:mavedb:00000044-a-1#4836,NA,NA,p.Tyr121Val,-0.84,-0.79,2,Y451V +urn:mavedb:00000044-a-1#4837,NA,NA,p.Tyr121Trp,-0.78,-0.85,1,Y451W +urn:mavedb:00000044-a-1#4838,NA,NA,p.Tyr121Trp,-0.92,-0.85,2,Y451W +urn:mavedb:00000044-a-1#4839,NA,NA,p.Tyr121*,NA,NA,1,Y451 +urn:mavedb:00000044-a-1#4840,NA,NA,p.Tyr121*,NA,NA,2,Y451 +urn:mavedb:00000044-a-1#4841,NA,NA,p.Leu122Ala,0.03,0.05,1,L452A +urn:mavedb:00000044-a-1#4842,NA,NA,p.Leu122Ala,0.08,0.05,2,L452A +urn:mavedb:00000044-a-1#4843,NA,NA,p.Leu122Cys,-0.09,-0.06,1,L452C +urn:mavedb:00000044-a-1#4844,NA,NA,p.Leu122Cys,-0.03,-0.06,2,L452C +urn:mavedb:00000044-a-1#4845,NA,NA,p.Leu122Asp,-0.12,-0.16,1,L452D +urn:mavedb:00000044-a-1#4846,NA,NA,p.Leu122Asp,-0.2,-0.16,2,L452D +urn:mavedb:00000044-a-1#4847,NA,NA,p.Leu122Glu,0.05,0.02,1,L452E +urn:mavedb:00000044-a-1#4848,NA,NA,p.Leu122Glu,-0.01,0.02,2,L452E +urn:mavedb:00000044-a-1#4849,NA,NA,p.Leu122Phe,-0.02,-0.01,1,L452F +urn:mavedb:00000044-a-1#4850,NA,NA,p.Leu122Phe,0,-0.01,2,L452F +urn:mavedb:00000044-a-1#4851,NA,NA,p.Leu122Gly,-0.02,0.02,1,L452G +urn:mavedb:00000044-a-1#4852,NA,NA,p.Leu122Gly,0.06,0.02,2,L452G +urn:mavedb:00000044-a-1#4853,NA,NA,p.Leu122His,-0.06,0,1,L452H +urn:mavedb:00000044-a-1#4854,NA,NA,p.Leu122His,0.05,0,2,L452H +urn:mavedb:00000044-a-1#4855,NA,NA,p.Leu122Ile,0.02,0,1,L452I +urn:mavedb:00000044-a-1#4856,NA,NA,p.Leu122Ile,-0.02,0,2,L452I +urn:mavedb:00000044-a-1#4857,NA,NA,p.Leu122Lys,0.11,0.09,1,L452K +urn:mavedb:00000044-a-1#4858,NA,NA,p.Leu122Lys,0.08,0.09,2,L452K +urn:mavedb:00000044-a-1#4859,NA,NA,p.Leu122Met,0.04,0.06,1,L452M +urn:mavedb:00000044-a-1#4860,NA,NA,p.Leu122Met,0.07,0.06,2,L452M +urn:mavedb:00000044-a-1#4861,NA,NA,p.Leu122Asn,0,0.01,1,L452N +urn:mavedb:00000044-a-1#4862,NA,NA,p.Leu122Asn,0.01,0.01,2,L452N +urn:mavedb:00000044-a-1#4863,NA,NA,p.Leu122Pro,-1.28,-1.43,1,L452P +urn:mavedb:00000044-a-1#4864,NA,NA,p.Leu122Pro,-1.57,-1.43,2,L452P +urn:mavedb:00000044-a-1#4865,NA,NA,p.Leu122Gln,0.1,0.07,1,L452Q +urn:mavedb:00000044-a-1#4866,NA,NA,p.Leu122Gln,0.04,0.07,2,L452Q +urn:mavedb:00000044-a-1#4867,NA,NA,p.Leu122Arg,-0.01,0.02,1,L452R +urn:mavedb:00000044-a-1#4868,NA,NA,p.Leu122Arg,0.04,0.02,2,L452R +urn:mavedb:00000044-a-1#4869,NA,NA,p.Leu122Ser,0.02,0.03,1,L452S +urn:mavedb:00000044-a-1#4870,NA,NA,p.Leu122Ser,0.05,0.03,2,L452S +urn:mavedb:00000044-a-1#4871,NA,NA,p.Leu122Thr,0.06,0.03,1,L452T +urn:mavedb:00000044-a-1#4872,NA,NA,p.Leu122Thr,0.01,0.03,2,L452T +urn:mavedb:00000044-a-1#4873,NA,NA,p.Leu122Val,0.06,0.02,1,L452V +urn:mavedb:00000044-a-1#4874,NA,NA,p.Leu122Val,-0.01,0.02,2,L452V +urn:mavedb:00000044-a-1#4875,NA,NA,p.Leu122Trp,-0.05,-0.06,1,L452W +urn:mavedb:00000044-a-1#4876,NA,NA,p.Leu122Trp,-0.07,-0.06,2,L452W +urn:mavedb:00000044-a-1#4877,NA,NA,p.Leu122Tyr,-0.08,-0.07,1,L452Y +urn:mavedb:00000044-a-1#5202,NA,NA,p.Leu131Ala,-0.99,-1,2,L461A +urn:mavedb:00000044-a-1#5203,NA,NA,p.Leu131Cys,-0.64,-0.63,1,L461C +urn:mavedb:00000044-a-1#5204,NA,NA,p.Leu131Cys,-0.63,-0.63,2,L461C +urn:mavedb:00000044-a-1#5205,NA,NA,p.Leu131Asp,-4.76,-4.8,1,L461D +urn:mavedb:00000044-a-1#5206,NA,NA,p.Leu131Asp,-4.84,-4.8,2,L461D +urn:mavedb:00000044-a-1#5207,NA,NA,p.Leu131Glu,-3.99,-4.12,1,L461E +urn:mavedb:00000044-a-1#5208,NA,NA,p.Leu131Glu,-4.26,-4.12,2,L461E +urn:mavedb:00000044-a-1#5209,NA,NA,p.Leu131Phe,-0.84,-0.88,1,L461F +urn:mavedb:00000044-a-1#5210,NA,NA,p.Leu131Phe,-0.91,-0.88,2,L461F +urn:mavedb:00000044-a-1#5211,NA,NA,p.Leu131Gly,-3.67,-3.34,1,L461G +urn:mavedb:00000044-a-1#5212,NA,NA,p.Leu131Gly,-3.02,-3.34,2,L461G +urn:mavedb:00000044-a-1#5213,NA,NA,p.Leu131His,-2.78,-2.22,1,L461H +urn:mavedb:00000044-a-1#5214,NA,NA,p.Leu131His,-1.66,-2.22,2,L461H +urn:mavedb:00000044-a-1#5215,NA,NA,p.Leu131Ile,0,-0.01,1,L461I +urn:mavedb:00000044-a-1#5216,NA,NA,p.Leu131Ile,-0.02,-0.01,2,L461I +urn:mavedb:00000044-a-1#5217,NA,NA,p.Leu131Lys,-3.39,-3.78,1,L461K +urn:mavedb:00000044-a-1#5218,NA,NA,p.Leu131Lys,-4.18,-3.78,2,L461K +urn:mavedb:00000044-a-1#5219,NA,NA,p.Leu131Met,-0.26,-0.22,1,L461M +urn:mavedb:00000044-a-1#5220,NA,NA,p.Leu131Met,-0.18,-0.22,2,L461M +urn:mavedb:00000044-a-1#5221,NA,NA,p.Leu131Asn,-0.84,-0.98,1,L461N +urn:mavedb:00000044-a-1#5222,NA,NA,p.Leu131Asn,-1.13,-0.98,2,L461N +urn:mavedb:00000044-a-1#5223,NA,NA,p.Leu131Pro,-2.73,-3.7,1,L461P +urn:mavedb:00000044-a-1#5224,NA,NA,p.Leu131Pro,-4.67,-3.7,2,L461P +urn:mavedb:00000044-a-1#5225,NA,NA,p.Leu131Gln,-1.14,-2.11,1,L461Q +urn:mavedb:00000044-a-1#5226,NA,NA,p.Leu131Gln,-3.09,-2.11,2,L461Q +urn:mavedb:00000044-a-1#5227,NA,NA,p.Leu131Arg,-4.76,-4.8,1,L461R +urn:mavedb:00000044-a-1#5228,NA,NA,p.Leu131Arg,-4.84,-4.8,2,L461R +urn:mavedb:00000044-a-1#5229,NA,NA,p.Leu131Ser,-1.31,-1.31,1,L461S +urn:mavedb:00000044-a-1#5230,NA,NA,p.Leu131Ser,-1.32,-1.31,2,L461S +urn:mavedb:00000044-a-1#5231,NA,NA,p.Leu131Thr,-0.73,-0.75,1,L461T +urn:mavedb:00000044-a-1#5232,NA,NA,p.Leu131Thr,-0.76,-0.75,2,L461T +urn:mavedb:00000044-a-1#5233,NA,NA,p.Leu131Val,-0.06,-0.04,1,L461V +urn:mavedb:00000044-a-1#5234,NA,NA,p.Leu131Val,-0.02,-0.04,2,L461V +urn:mavedb:00000044-a-1#5235,NA,NA,p.Leu131Trp,-4.76,-4.56,1,L461W +urn:mavedb:00000044-a-1#5236,NA,NA,p.Leu131Trp,-4.35,-4.56,2,L461W +urn:mavedb:00000044-a-1#5237,NA,NA,p.Leu131Tyr,-1.1,-1.14,1,L461Y +urn:mavedb:00000044-a-1#5238,NA,NA,p.Leu131Tyr,-1.17,-1.14,2,L461Y +urn:mavedb:00000044-a-1#5239,NA,NA,p.Leu131*,NA,NA,1,L461 +urn:mavedb:00000044-a-1#5240,NA,NA,p.Leu131*,NA,NA,2,L461 +urn:mavedb:00000044-a-1#5241,NA,NA,p.Lys132Ala,-0.06,-0.07,1,K462A +urn:mavedb:00000044-a-1#5242,NA,NA,p.Lys132Ala,-0.07,-0.07,2,K462A +urn:mavedb:00000044-a-1#5243,NA,NA,p.Lys132Cys,-0.12,-0.11,1,K462C +urn:mavedb:00000044-a-1#5244,NA,NA,p.Lys132Cys,-0.1,-0.11,2,K462C +urn:mavedb:00000044-a-1#5245,NA,NA,p.Lys132Asp,-0.09,-0.08,1,K462D +urn:mavedb:00000044-a-1#5246,NA,NA,p.Lys132Asp,-0.06,-0.08,2,K462D +urn:mavedb:00000044-a-1#5247,NA,NA,p.Lys132Glu,0.02,-0.01,1,K462E +urn:mavedb:00000044-a-1#5248,NA,NA,p.Lys132Glu,-0.03,-0.01,2,K462E +urn:mavedb:00000044-a-1#5249,NA,NA,p.Lys132Phe,-0.08,-0.09,1,K462F +urn:mavedb:00000044-a-1#5250,NA,NA,p.Lys132Phe,-0.09,-0.09,2,K462F +urn:mavedb:00000044-a-1#5251,NA,NA,p.Lys132Gly,-0.06,-0.06,1,K462G +urn:mavedb:00000044-a-1#5252,NA,NA,p.Lys132Gly,-0.06,-0.06,2,K462G +urn:mavedb:00000044-a-1#5253,NA,NA,p.Lys132His,0.05,-0.24,1,K462H +urn:mavedb:00000044-a-1#5254,NA,NA,p.Lys132His,-0.52,-0.24,2,K462H +urn:mavedb:00000044-a-1#5255,NA,NA,p.Lys132Ile,-0.12,-0.13,1,K462I +urn:mavedb:00000044-a-1#5256,NA,NA,p.Lys132Ile,-0.14,-0.13,2,K462I +urn:mavedb:00000044-a-1#5257,NA,NA,p.Lys132Leu,-0.05,-0.07,1,K462L +urn:mavedb:00000044-a-1#5258,NA,NA,p.Lys132Leu,-0.1,-0.07,2,K462L +urn:mavedb:00000044-a-1#5259,NA,NA,p.Lys132Met,-0.02,-0.04,1,K462M +urn:mavedb:00000044-a-1#5260,NA,NA,p.Lys132Met,-0.05,-0.04,2,K462M +urn:mavedb:00000044-a-1#5261,NA,NA,p.Lys132Asn,-0.03,-0.08,1,K462N 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+urn:mavedb:00000044-a-1#5773,NA,NA,p.Ala145Ile,-0.46,-0.48,1,A475I +urn:mavedb:00000044-a-1#5774,NA,NA,p.Ala145Ile,-0.51,-0.48,2,A475I +urn:mavedb:00000044-a-1#5775,NA,NA,p.Ala145Lys,-0.93,-1.06,1,A475K +urn:mavedb:00000044-a-1#5776,NA,NA,p.Ala145Lys,-1.19,-1.06,2,A475K +urn:mavedb:00000044-a-1#5777,NA,NA,p.Ala145Leu,-1.19,-1.27,1,A475L +urn:mavedb:00000044-a-1#5778,NA,NA,p.Ala145Leu,-1.35,-1.27,2,A475L +urn:mavedb:00000044-a-1#5779,NA,NA,p.Ala145Met,-0.33,-0.38,1,A475M +urn:mavedb:00000044-a-1#5780,NA,NA,p.Ala145Met,-0.43,-0.38,2,A475M +urn:mavedb:00000044-a-1#5781,NA,NA,p.Ala145Asn,-1.73,-1.67,1,A475N +urn:mavedb:00000044-a-1#5782,NA,NA,p.Ala145Asn,-1.61,-1.67,2,A475N +urn:mavedb:00000044-a-1#5783,NA,NA,p.Ala145Pro,-1.52,-1.62,1,A475P +urn:mavedb:00000044-a-1#5784,NA,NA,p.Ala145Pro,-1.72,-1.62,2,A475P +urn:mavedb:00000044-a-1#5785,NA,NA,p.Ala145Gln,-0.75,-0.8,1,A475Q +urn:mavedb:00000044-a-1#5786,NA,NA,p.Ala145Gln,-0.84,-0.8,2,A475Q +urn:mavedb:00000044-a-1#5787,NA,NA,p.Ala145Arg,-0.77,-0.86,1,A475R +urn:mavedb:00000044-a-1#5788,NA,NA,p.Ala145Arg,-0.95,-0.86,2,A475R +urn:mavedb:00000044-a-1#5789,NA,NA,p.Ala145Ser,-0.08,-0.1,1,A475S +urn:mavedb:00000044-a-1#5790,NA,NA,p.Ala145Ser,-0.13,-0.1,2,A475S +urn:mavedb:00000044-a-1#5791,NA,NA,p.Ala145Thr,-0.35,-0.36,1,A475T +urn:mavedb:00000044-a-1#5826,NA,NA,p.Gly146Gln,-1.18,-1.12,2,G476Q +urn:mavedb:00000044-a-1#5792,NA,NA,p.Ala145Thr,-0.37,-0.36,2,A475T +urn:mavedb:00000044-a-1#5793,NA,NA,p.Ala145Val,-0.11,-0.14,1,A475V +urn:mavedb:00000044-a-1#5794,NA,NA,p.Ala145Val,-0.17,-0.14,2,A475V +urn:mavedb:00000044-a-1#5795,NA,NA,p.Ala145Trp,-2.21,-2.26,1,A475W +urn:mavedb:00000044-a-1#5796,NA,NA,p.Ala145Trp,-2.32,-2.26,2,A475W +urn:mavedb:00000044-a-1#5797,NA,NA,p.Ala145Tyr,-1.63,-1.69,1,A475Y +urn:mavedb:00000044-a-1#5798,NA,NA,p.Ala145Tyr,-1.75,-1.69,2,A475Y +urn:mavedb:00000044-a-1#5800,NA,NA,p.Ala145*,NA,NA,2,A475 +urn:mavedb:00000044-a-1#5801,NA,NA,p.Gly146Ala,-0.37,-0.26,1,G476A +urn:mavedb:00000044-a-1#5802,NA,NA,p.Gly146Ala,-0.15,-0.26,2,G476A +urn:mavedb:00000044-a-1#5803,NA,NA,p.Gly146Cys,-1.96,-1.89,1,G476C +urn:mavedb:00000044-a-1#5804,NA,NA,p.Gly146Cys,-1.82,-1.89,2,G476C +urn:mavedb:00000044-a-1#5805,NA,NA,p.Gly146Asp,-0.5,-0.54,1,G476D +urn:mavedb:00000044-a-1#5806,NA,NA,p.Gly146Asp,-0.58,-0.54,2,G476D +urn:mavedb:00000044-a-1#5807,NA,NA,p.Gly146Glu,-1.34,-1.35,1,G476E +urn:mavedb:00000044-a-1#5808,NA,NA,p.Gly146Glu,-1.36,-1.35,2,G476E +urn:mavedb:00000044-a-1#5809,NA,NA,p.Gly146Phe,-1.11,-1.22,1,G476F +urn:mavedb:00000044-a-1#5810,NA,NA,p.Gly146Phe,-1.33,-1.22,2,G476F +urn:mavedb:00000044-a-1#5811,NA,NA,p.Gly146His,-0.29,-0.38,1,G476H +urn:mavedb:00000044-a-1#5812,NA,NA,p.Gly146His,-0.48,-0.38,2,G476H +urn:mavedb:00000044-a-1#5813,NA,NA,p.Gly146Ile,-2.21,-2.31,1,G476I +urn:mavedb:00000044-a-1#5814,NA,NA,p.Gly146Ile,-2.42,-2.31,2,G476I +urn:mavedb:00000044-a-1#5815,NA,NA,p.Gly146Lys,-1.62,-1.68,1,G476K +urn:mavedb:00000044-a-1#5816,NA,NA,p.Gly146Lys,-1.73,-1.68,2,G476K +urn:mavedb:00000044-a-1#5817,NA,NA,p.Gly146Leu,-2.43,-2.51,1,G476L +urn:mavedb:00000044-a-1#5818,NA,NA,p.Gly146Leu,-2.59,-2.51,2,G476L +urn:mavedb:00000044-a-1#5819,NA,NA,p.Gly146Met,-1.62,-1.67,1,G476M +urn:mavedb:00000044-a-1#5820,NA,NA,p.Gly146Met,-1.72,-1.67,2,G476M +urn:mavedb:00000044-a-1#5821,NA,NA,p.Gly146Asn,-0.72,-0.84,1,G476N +urn:mavedb:00000044-a-1#5822,NA,NA,p.Gly146Asn,-0.95,-0.84,2,G476N +urn:mavedb:00000044-a-1#5823,NA,NA,p.Gly146Pro,-2.59,-2.56,1,G476P +urn:mavedb:00000044-a-1#5824,NA,NA,p.Gly146Pro,-2.52,-2.56,2,G476P +urn:mavedb:00000044-a-1#5825,NA,NA,p.Gly146Gln,-1.06,-1.12,1,G476Q +urn:mavedb:00000044-a-1#5827,NA,NA,p.Gly146Arg,-1.08,-1.18,1,G476R +urn:mavedb:00000044-a-1#5828,NA,NA,p.Gly146Arg,-1.28,-1.18,2,G476R +urn:mavedb:00000044-a-1#5829,NA,NA,p.Gly146Ser,-0.02,-0.02,1,G476S 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+urn:mavedb:00000044-a-1#5873,NA,NA,p.Ser147Val,-0.02,-0.05,1,S477V +urn:mavedb:00000044-a-1#5874,NA,NA,p.Ser147Val,-0.08,-0.05,2,S477V +urn:mavedb:00000044-a-1#5875,NA,NA,p.Ser147Trp,0,0.02,1,S477W +urn:mavedb:00000044-a-1#5876,NA,NA,p.Ser147Trp,0.04,0.02,2,S477W +urn:mavedb:00000044-a-1#5877,NA,NA,p.Ser147Tyr,-0.04,-0.02,1,S477Y +urn:mavedb:00000044-a-1#5878,NA,NA,p.Ser147Tyr,0,-0.02,2,S477Y +urn:mavedb:00000044-a-1#5881,NA,NA,p.Thr148Ala,-0.02,-0.03,1,T478A +urn:mavedb:00000044-a-1#5882,NA,NA,p.Thr148Ala,-0.03,-0.03,2,T478A +urn:mavedb:00000044-a-1#5883,NA,NA,p.Thr148Cys,-0.22,-0.25,1,T478C +urn:mavedb:00000044-a-1#5884,NA,NA,p.Thr148Cys,-0.28,-0.25,2,T478C +urn:mavedb:00000044-a-1#5885,NA,NA,p.Thr148Asp,-0.05,-0.06,1,T478D +urn:mavedb:00000044-a-1#5886,NA,NA,p.Thr148Asp,-0.07,-0.06,2,T478D +urn:mavedb:00000044-a-1#5887,NA,NA,p.Thr148Glu,-0.08,-0.07,1,T478E +urn:mavedb:00000044-a-1#5888,NA,NA,p.Thr148Glu,-0.05,-0.07,2,T478E 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+urn:mavedb:00000044-a-1#5903,NA,NA,p.Thr148Asn,-0.06,-0.06,1,T478N +urn:mavedb:00000044-a-1#5904,NA,NA,p.Thr148Asn,-0.06,-0.06,2,T478N +urn:mavedb:00000044-a-1#5905,NA,NA,p.Thr148Pro,-0.29,-0.31,1,T478P +urn:mavedb:00000044-a-1#5906,NA,NA,p.Thr148Pro,-0.33,-0.31,2,T478P +urn:mavedb:00000044-a-1#5907,NA,NA,p.Thr148Gln,0.04,0.01,1,T478Q +urn:mavedb:00000044-a-1#5908,NA,NA,p.Thr148Gln,-0.01,0.01,2,T478Q +urn:mavedb:00000044-a-1#5909,NA,NA,p.Thr148Arg,-0.06,-0.04,1,T478R +urn:mavedb:00000044-a-1#5910,NA,NA,p.Thr148Arg,-0.02,-0.04,2,T478R +urn:mavedb:00000044-a-1#5911,NA,NA,p.Thr148Ser,-0.01,-0.01,1,T478S +urn:mavedb:00000044-a-1#5912,NA,NA,p.Thr148Ser,0,-0.01,2,T478S +urn:mavedb:00000044-a-1#5913,NA,NA,p.Thr148Val,-0.06,-0.06,1,T478V +urn:mavedb:00000044-a-1#5914,NA,NA,p.Thr148Val,-0.06,-0.06,2,T478V +urn:mavedb:00000044-a-1#5915,NA,NA,p.Thr148Trp,-0.08,-0.11,1,T478W +urn:mavedb:00000044-a-1#5916,NA,NA,p.Thr148Trp,-0.12,-0.11,2,T478W +urn:mavedb:00000044-a-1#5917,NA,NA,p.Thr148Tyr,-0.07,-0.04,1,T478Y +urn:mavedb:00000044-a-1#5918,NA,NA,p.Thr148Tyr,-0.01,-0.04,2,T478Y +urn:mavedb:00000044-a-1#5919,NA,NA,p.Thr148*,NA,NA,1,T478 +urn:mavedb:00000044-a-1#5920,NA,NA,p.Thr148*,NA,NA,2,T478 +urn:mavedb:00000044-a-1#5921,NA,NA,p.Pro149Ala,-0.03,-0.02,1,P479A +urn:mavedb:00000044-a-1#5922,NA,NA,p.Pro149Ala,0,-0.02,2,P479A +urn:mavedb:00000044-a-1#5923,NA,NA,p.Pro149Cys,-0.11,-0.17,1,P479C +urn:mavedb:00000044-a-1#5924,NA,NA,p.Pro149Cys,-0.23,-0.17,2,P479C +urn:mavedb:00000044-a-1#5925,NA,NA,p.Pro149Asp,-0.06,-0.03,1,P479D +urn:mavedb:00000044-a-1#5926,NA,NA,p.Pro149Asp,0,-0.03,2,P479D +urn:mavedb:00000044-a-1#5927,NA,NA,p.Pro149Glu,0.05,0.02,1,P479E +urn:mavedb:00000044-a-1#5928,NA,NA,p.Pro149Glu,0,0.02,2,P479E +urn:mavedb:00000044-a-1#5929,NA,NA,p.Pro149Phe,-0.11,-0.11,1,P479F +urn:mavedb:00000044-a-1#5930,NA,NA,p.Pro149Phe,-0.11,-0.11,2,P479F +urn:mavedb:00000044-a-1#5931,NA,NA,p.Pro149Gly,-0.04,-0.04,1,P479G +urn:mavedb:00000044-a-1#5932,NA,NA,p.Pro149Gly,-0.03,-0.04,2,P479G +urn:mavedb:00000044-a-1#5933,NA,NA,p.Pro149His,-0.05,-0.07,1,P479H +urn:mavedb:00000044-a-1#5934,NA,NA,p.Pro149His,-0.09,-0.07,2,P479H +urn:mavedb:00000044-a-1#5935,NA,NA,p.Pro149Ile,-0.1,-0.13,1,P479I +urn:mavedb:00000044-a-1#5936,NA,NA,p.Pro149Ile,-0.16,-0.13,2,P479I +urn:mavedb:00000044-a-1#5937,NA,NA,p.Pro149Lys,-0.05,-0.03,1,P479K +urn:mavedb:00000044-a-1#5938,NA,NA,p.Pro149Lys,0,-0.03,2,P479K +urn:mavedb:00000044-a-1#5939,NA,NA,p.Pro149Leu,-0.04,-0.06,1,P479L +urn:mavedb:00000044-a-1#5940,NA,NA,p.Pro149Leu,-0.07,-0.06,2,P479L +urn:mavedb:00000044-a-1#5941,NA,NA,p.Pro149Met,-0.02,-0.05,1,P479M +urn:mavedb:00000044-a-1#5942,NA,NA,p.Pro149Met,-0.08,-0.05,2,P479M +urn:mavedb:00000044-a-1#5943,NA,NA,p.Pro149Asn,0.01,-0.05,1,P479N +urn:mavedb:00000044-a-1#5944,NA,NA,p.Pro149Asn,-0.11,-0.05,2,P479N +urn:mavedb:00000044-a-1#5945,NA,NA,p.Pro149Gln,-0.03,-0.03,1,P479Q +urn:mavedb:00000044-a-1#5946,NA,NA,p.Pro149Gln,-0.04,-0.03,2,P479Q +urn:mavedb:00000044-a-1#5947,NA,NA,p.Pro149Arg,-0.05,-0.06,1,P479R +urn:mavedb:00000044-a-1#5948,NA,NA,p.Pro149Arg,-0.08,-0.06,2,P479R +urn:mavedb:00000044-a-1#5949,NA,NA,p.Pro149Ser,-0.01,-0.03,1,P479S +urn:mavedb:00000044-a-1#5950,NA,NA,p.Pro149Ser,-0.05,-0.03,2,P479S +urn:mavedb:00000044-a-1#5951,NA,NA,p.Pro149Thr,-0.15,-0.1,1,P479T +urn:mavedb:00000044-a-1#5952,NA,NA,p.Pro149Thr,-0.06,-0.1,2,P479T +urn:mavedb:00000044-a-1#5953,NA,NA,p.Pro149Val,-0.04,-0.07,1,P479V +urn:mavedb:00000044-a-1#5954,NA,NA,p.Pro149Val,-0.1,-0.07,2,P479V +urn:mavedb:00000044-a-1#5955,NA,NA,p.Pro149Trp,-0.5,-0.29,1,P479W +urn:mavedb:00000044-a-1#5956,NA,NA,p.Pro149Trp,-0.09,-0.29,2,P479W +urn:mavedb:00000044-a-1#5957,NA,NA,p.Pro149Tyr,-0.06,-0.08,1,P479Y +urn:mavedb:00000044-a-1#5958,NA,NA,p.Pro149Tyr,-0.1,-0.08,2,P479Y +urn:mavedb:00000044-a-1#5959,NA,NA,p.Pro149*,NA,NA,1,P479 +urn:mavedb:00000044-a-1#5960,NA,NA,p.Pro149*,NA,NA,2,P479 +urn:mavedb:00000044-a-1#5961,NA,NA,p.Cys150Ala,-3.6,-3.45,1,C480A +urn:mavedb:00000044-a-1#5962,NA,NA,p.Cys150Ala,-3.29,-3.45,2,C480A +urn:mavedb:00000044-a-1#5963,NA,NA,p.Cys150Asp,-3.01,-3.29,1,C480D +urn:mavedb:00000044-a-1#5964,NA,NA,p.Cys150Asp,-3.58,-3.29,2,C480D +urn:mavedb:00000044-a-1#5965,NA,NA,p.Cys150Glu,-3.65,-3.59,1,C480E +urn:mavedb:00000044-a-1#5966,NA,NA,p.Cys150Glu,-3.52,-3.59,2,C480E +urn:mavedb:00000044-a-1#5967,NA,NA,p.Cys150Phe,-4.11,-3.84,1,C480F +urn:mavedb:00000044-a-1#5968,NA,NA,p.Cys150Phe,-3.58,-3.84,2,C480F +urn:mavedb:00000044-a-1#5969,NA,NA,p.Cys150Gly,-3.41,-3.44,1,C480G +urn:mavedb:00000044-a-1#5970,NA,NA,p.Cys150Gly,-3.47,-3.44,2,C480G +urn:mavedb:00000044-a-1#5971,NA,NA,p.Cys150His,-3.76,-3.65,1,C480H +urn:mavedb:00000044-a-1#5972,NA,NA,p.Cys150His,-3.55,-3.65,2,C480H +urn:mavedb:00000044-a-1#5973,NA,NA,p.Cys150Ile,-3.65,-3.81,1,C480I +urn:mavedb:00000044-a-1#5974,NA,NA,p.Cys150Ile,-3.98,-3.81,2,C480I +urn:mavedb:00000044-a-1#5975,NA,NA,p.Cys150Lys,-3.66,-3.72,1,C480K +urn:mavedb:00000044-a-1#5976,NA,NA,p.Cys150Lys,-3.78,-3.72,2,C480K +urn:mavedb:00000044-a-1#5977,NA,NA,p.Cys150Leu,-3.75,-3.86,1,C480L +urn:mavedb:00000044-a-1#5978,NA,NA,p.Cys150Leu,-3.96,-3.86,2,C480L +urn:mavedb:00000044-a-1#5979,NA,NA,p.Cys150Met,-4.13,-3.94,1,C480M +urn:mavedb:00000044-a-1#5980,NA,NA,p.Cys150Met,-3.76,-3.94,2,C480M +urn:mavedb:00000044-a-1#5981,NA,NA,p.Cys150Asn,-3.46,-3.47,1,C480N +urn:mavedb:00000044-a-1#5982,NA,NA,p.Cys150Asn,-3.47,-3.47,2,C480N +urn:mavedb:00000044-a-1#5983,NA,NA,p.Cys150Pro,-3.6,-3.52,1,C480P +urn:mavedb:00000044-a-1#5984,NA,NA,p.Cys150Pro,-3.44,-3.52,2,C480P +urn:mavedb:00000044-a-1#5985,NA,NA,p.Cys150Gln,-3.43,-3.8,1,C480Q +urn:mavedb:00000044-a-1#5986,NA,NA,p.Cys150Gln,-4.18,-3.8,2,C480Q +urn:mavedb:00000044-a-1#5987,NA,NA,p.Cys150Arg,-3.7,-3.56,1,C480R +urn:mavedb:00000044-a-1#5988,NA,NA,p.Cys150Arg,-3.42,-3.56,2,C480R +urn:mavedb:00000044-a-1#5989,NA,NA,p.Cys150Ser,-3.33,-3.38,1,C480S +urn:mavedb:00000044-a-1#5990,NA,NA,p.Cys150Ser,-3.42,-3.38,2,C480S +urn:mavedb:00000044-a-1#5991,NA,NA,p.Cys150Thr,-3.48,-3.49,1,C480T +urn:mavedb:00000044-a-1#5992,NA,NA,p.Cys150Thr,-3.5,-3.49,2,C480T +urn:mavedb:00000044-a-1#5993,NA,NA,p.Cys150Val,-3.26,-3.35,1,C480V +urn:mavedb:00000044-a-1#5994,NA,NA,p.Cys150Val,-3.44,-3.35,2,C480V +urn:mavedb:00000044-a-1#5995,NA,NA,p.Cys150Trp,-3.27,-3.62,1,C480W +urn:mavedb:00000044-a-1#5996,NA,NA,p.Cys150Trp,-3.98,-3.62,2,C480W +urn:mavedb:00000044-a-1#5997,NA,NA,p.Cys150Tyr,-3.6,-3.55,1,C480Y +urn:mavedb:00000044-a-1#5998,NA,NA,p.Cys150Tyr,-3.5,-3.55,2,C480Y +urn:mavedb:00000044-a-1#5999,NA,NA,p.Cys150*,NA,NA,1,C480 +urn:mavedb:00000044-a-1#6000,NA,NA,p.Cys150*,NA,NA,2,C480 +urn:mavedb:00000044-a-1#6001,NA,NA,p.Asn151Ala,-0.05,-0.06,1,N481A +urn:mavedb:00000044-a-1#6002,NA,NA,p.Asn151Ala,-0.07,-0.06,2,N481A +urn:mavedb:00000044-a-1#6003,NA,NA,p.Asn151Cys,-0.14,-0.17,1,N481C +urn:mavedb:00000044-a-1#6004,NA,NA,p.Asn151Cys,-0.2,-0.17,2,N481C +urn:mavedb:00000044-a-1#6005,NA,NA,p.Asn151Asp,-0.06,-0.07,1,N481D +urn:mavedb:00000044-a-1#6006,NA,NA,p.Asn151Asp,-0.08,-0.07,2,N481D +urn:mavedb:00000044-a-1#6007,NA,NA,p.Asn151Glu,-0.1,-0.08,1,N481E +urn:mavedb:00000044-a-1#6008,NA,NA,p.Asn151Glu,-0.05,-0.08,2,N481E +urn:mavedb:00000044-a-1#6009,NA,NA,p.Asn151Phe,-0.1,-0.08,1,N481F +urn:mavedb:00000044-a-1#6010,NA,NA,p.Asn151Phe,-0.07,-0.08,2,N481F +urn:mavedb:00000044-a-1#6011,NA,NA,p.Asn151Gly,-0.09,-0.08,1,N481G +urn:mavedb:00000044-a-1#6012,NA,NA,p.Asn151Gly,-0.08,-0.08,2,N481G +urn:mavedb:00000044-a-1#6013,NA,NA,p.Asn151His,0,-0.02,1,N481H +urn:mavedb:00000044-a-1#6014,NA,NA,p.Asn151His,-0.04,-0.02,2,N481H +urn:mavedb:00000044-a-1#6015,NA,NA,p.Asn151Ile,-0.16,-0.19,1,N481I +urn:mavedb:00000044-a-1#6016,NA,NA,p.Asn151Ile,-0.22,-0.19,2,N481I +urn:mavedb:00000044-a-1#6017,NA,NA,p.Asn151Lys,0.03,0.01,1,N481K +urn:mavedb:00000044-a-1#6018,NA,NA,p.Asn151Lys,0,0.01,2,N481K +urn:mavedb:00000044-a-1#6019,NA,NA,p.Asn151Leu,-0.06,-0.05,1,N481L +urn:mavedb:00000044-a-1#6020,NA,NA,p.Asn151Leu,-0.04,-0.05,2,N481L +urn:mavedb:00000044-a-1#6021,NA,NA,p.Asn151Met,0.04,-0.02,1,N481M +urn:mavedb:00000044-a-1#6022,NA,NA,p.Asn151Met,-0.07,-0.02,2,N481M +urn:mavedb:00000044-a-1#6023,NA,NA,p.Asn151Pro,-0.22,-0.29,1,N481P +urn:mavedb:00000044-a-1#6024,NA,NA,p.Asn151Pro,-0.37,-0.29,2,N481P +urn:mavedb:00000044-a-1#6025,NA,NA,p.Asn151Gln,-0.03,-0.04,1,N481Q +urn:mavedb:00000044-a-1#6026,NA,NA,p.Asn151Gln,-0.05,-0.04,2,N481Q +urn:mavedb:00000044-a-1#6027,NA,NA,p.Asn151Arg,0.02,0.02,1,N481R +urn:mavedb:00000044-a-1#6028,NA,NA,p.Asn151Arg,0.01,0.02,2,N481R +urn:mavedb:00000044-a-1#6029,NA,NA,p.Asn151Ser,-0.05,-0.04,1,N481S +urn:mavedb:00000044-a-1#6030,NA,NA,p.Asn151Ser,-0.03,-0.04,2,N481S +urn:mavedb:00000044-a-1#6031,NA,NA,p.Asn151Thr,-0.08,-0.11,1,N481T +urn:mavedb:00000044-a-1#6032,NA,NA,p.Asn151Thr,-0.14,-0.11,2,N481T +urn:mavedb:00000044-a-1#6033,NA,NA,p.Asn151Val,-0.09,-0.12,1,N481V +urn:mavedb:00000044-a-1#6034,NA,NA,p.Asn151Val,-0.16,-0.12,2,N481V +urn:mavedb:00000044-a-1#6035,NA,NA,p.Asn151Trp,-0.1,-0.09,1,N481W +urn:mavedb:00000044-a-1#6036,NA,NA,p.Asn151Trp,-0.08,-0.09,2,N481W +urn:mavedb:00000044-a-1#6037,NA,NA,p.Asn151Tyr,-0.1,-0.08,1,N481Y +urn:mavedb:00000044-a-1#6038,NA,NA,p.Asn151Tyr,-0.06,-0.08,2,N481Y +urn:mavedb:00000044-a-1#6039,NA,NA,p.Asn151*,NA,NA,1,N481 +urn:mavedb:00000044-a-1#6040,NA,NA,p.Asn151*,NA,NA,2,N481 +urn:mavedb:00000044-a-1#6041,NA,NA,p.Gly152Ala,-0.08,-0.08,1,G482A +urn:mavedb:00000044-a-1#6042,NA,NA,p.Gly152Ala,-0.07,-0.08,2,G482A +urn:mavedb:00000044-a-1#6043,NA,NA,p.Gly152Cys,-0.26,-0.3,1,G482C +urn:mavedb:00000044-a-1#6044,NA,NA,p.Gly152Cys,-0.34,-0.3,2,G482C +urn:mavedb:00000044-a-1#6045,NA,NA,p.Gly152Asp,0,-0.02,1,G482D +urn:mavedb:00000044-a-1#6046,NA,NA,p.Gly152Asp,-0.04,-0.02,2,G482D +urn:mavedb:00000044-a-1#6047,NA,NA,p.Gly152Glu,-0.07,-0.03,1,G482E +urn:mavedb:00000044-a-1#6048,NA,NA,p.Gly152Glu,0.01,-0.03,2,G482E +urn:mavedb:00000044-a-1#6049,NA,NA,p.Gly152Phe,-0.22,-0.23,1,G482F +urn:mavedb:00000044-a-1#6050,NA,NA,p.Gly152Phe,-0.24,-0.23,2,G482F +urn:mavedb:00000044-a-1#6051,NA,NA,p.Gly152His,0,-0.06,1,G482H +urn:mavedb:00000044-a-1#6052,NA,NA,p.Gly152His,-0.12,-0.06,2,G482H +urn:mavedb:00000044-a-1#6053,NA,NA,p.Gly152Ile,-0.51,-0.57,1,G482I +urn:mavedb:00000044-a-1#6054,NA,NA,p.Gly152Ile,-0.64,-0.57,2,G482I +urn:mavedb:00000044-a-1#6055,NA,NA,p.Gly152Lys,-0.05,-0.06,1,G482K +urn:mavedb:00000044-a-1#6056,NA,NA,p.Gly152Lys,-0.06,-0.06,2,G482K +urn:mavedb:00000044-a-1#6057,NA,NA,p.Gly152Leu,-0.15,-0.19,1,G482L +urn:mavedb:00000044-a-1#6058,NA,NA,p.Gly152Leu,-0.22,-0.19,2,G482L +urn:mavedb:00000044-a-1#6059,NA,NA,p.Gly152Met,-0.23,-0.25,1,G482M +urn:mavedb:00000044-a-1#6060,NA,NA,p.Gly152Met,-0.27,-0.25,2,G482M +urn:mavedb:00000044-a-1#6061,NA,NA,p.Gly152Asn,0.05,-0.02,1,G482N +urn:mavedb:00000044-a-1#6062,NA,NA,p.Gly152Asn,-0.09,-0.02,2,G482N +urn:mavedb:00000044-a-1#6063,NA,NA,p.Gly152Pro,-0.51,-0.53,1,G482P +urn:mavedb:00000044-a-1#6064,NA,NA,p.Gly152Pro,-0.55,-0.53,2,G482P +urn:mavedb:00000044-a-1#6065,NA,NA,p.Gly152Gln,0.11,0.04,1,G482Q +urn:mavedb:00000044-a-1#4881,NA,NA,p.Tyr123Ala,-0.21,-0.27,1,Y453A +urn:mavedb:00000044-a-1#4882,NA,NA,p.Tyr123Ala,-0.33,-0.27,2,Y453A +urn:mavedb:00000044-a-1#4883,NA,NA,p.Tyr123Cys,-0.28,-0.26,1,Y453C +urn:mavedb:00000044-a-1#4884,NA,NA,p.Tyr123Cys,-0.25,-0.26,2,Y453C +urn:mavedb:00000044-a-1#4885,NA,NA,p.Tyr123Asp,-3.6,-3.49,1,Y453D +urn:mavedb:00000044-a-1#4886,NA,NA,p.Tyr123Asp,-3.38,-3.49,2,Y453D +urn:mavedb:00000044-a-1#4887,NA,NA,p.Tyr123Glu,-1.26,-1.18,1,Y453E +urn:mavedb:00000044-a-1#4888,NA,NA,p.Tyr123Glu,-1.1,-1.18,2,Y453E +urn:mavedb:00000044-a-1#4889,NA,NA,p.Tyr123Phe,0.19,0.25,1,Y453F +urn:mavedb:00000044-a-1#4890,NA,NA,p.Tyr123Phe,0.31,0.25,2,Y453F +urn:mavedb:00000044-a-1#4891,NA,NA,p.Tyr123Gly,-0.82,-0.92,1,Y453G +urn:mavedb:00000044-a-1#4892,NA,NA,p.Tyr123Gly,-1.01,-0.92,2,Y453G +urn:mavedb:00000044-a-1#4893,NA,NA,p.Tyr123His,-0.05,-0.07,1,Y453H +urn:mavedb:00000044-a-1#4894,NA,NA,p.Tyr123His,-0.1,-0.07,2,Y453H +urn:mavedb:00000044-a-1#4895,NA,NA,p.Tyr123Ile,-0.43,-0.53,1,Y453I +urn:mavedb:00000044-a-1#4896,NA,NA,p.Tyr123Ile,-0.63,-0.53,2,Y453I +urn:mavedb:00000044-a-1#4897,NA,NA,p.Tyr123Lys,0.01,0.08,1,Y453K +urn:mavedb:00000044-a-1#4898,NA,NA,p.Tyr123Lys,0.16,0.08,2,Y453K +urn:mavedb:00000044-a-1#4899,NA,NA,p.Tyr123Leu,-0.16,-0.17,1,Y453L +urn:mavedb:00000044-a-1#4900,NA,NA,p.Tyr123Leu,-0.18,-0.17,2,Y453L +urn:mavedb:00000044-a-1#4901,NA,NA,p.Tyr123Met,-0.02,-0.05,1,Y453M +urn:mavedb:00000044-a-1#4902,NA,NA,p.Tyr123Met,-0.08,-0.05,2,Y453M +urn:mavedb:00000044-a-1#4903,NA,NA,p.Tyr123Asn,-0.83,-0.82,1,Y453N +urn:mavedb:00000044-a-1#4904,NA,NA,p.Tyr123Asn,-0.81,-0.82,2,Y453N +urn:mavedb:00000044-a-1#4905,NA,NA,p.Tyr123Pro,-4.76,-4.8,1,Y453P +urn:mavedb:00000044-a-1#4906,NA,NA,p.Tyr123Pro,-4.84,-4.8,2,Y453P +urn:mavedb:00000044-a-1#4907,NA,NA,p.Tyr123Gln,-0.36,-0.37,1,Y453Q +urn:mavedb:00000044-a-1#4908,NA,NA,p.Tyr123Gln,-0.39,-0.37,2,Y453Q +urn:mavedb:00000044-a-1#4909,NA,NA,p.Tyr123Arg,-0.31,-0.3,1,Y453R +urn:mavedb:00000044-a-1#4910,NA,NA,p.Tyr123Arg,-0.29,-0.3,2,Y453R +urn:mavedb:00000044-a-1#4911,NA,NA,p.Tyr123Ser,-0.14,-0.21,1,Y453S +urn:mavedb:00000044-a-1#4912,NA,NA,p.Tyr123Ser,-0.29,-0.21,2,Y453S +urn:mavedb:00000044-a-1#4913,NA,NA,p.Tyr123Thr,-0.46,-0.55,1,Y453T +urn:mavedb:00000044-a-1#4914,NA,NA,p.Tyr123Thr,-0.64,-0.55,2,Y453T +urn:mavedb:00000044-a-1#4915,NA,NA,p.Tyr123Val,-0.13,-0.11,1,Y453V +urn:mavedb:00000044-a-1#4916,NA,NA,p.Tyr123Val,-0.1,-0.11,2,Y453V +urn:mavedb:00000044-a-1#4917,NA,NA,p.Tyr123Trp,-0.1,-0.16,1,Y453W +urn:mavedb:00000044-a-1#4918,NA,NA,p.Tyr123Trp,-0.21,-0.16,2,Y453W +urn:mavedb:00000044-a-1#4919,NA,NA,p.Tyr123*,NA,NA,1,Y453 +urn:mavedb:00000044-a-1#4920,NA,NA,p.Tyr123*,NA,NA,2,Y453 +urn:mavedb:00000044-a-1#4921,NA,NA,p.Arg124Ala,-3.1,-3.04,1,R454A +urn:mavedb:00000044-a-1#4922,NA,NA,p.Arg124Ala,-2.98,-3.04,2,R454A +urn:mavedb:00000044-a-1#4923,NA,NA,p.Arg124Cys,-4.76,-4.8,1,R454C +urn:mavedb:00000044-a-1#4924,NA,NA,p.Arg124Cys,-4.84,-4.8,2,R454C +urn:mavedb:00000044-a-1#4925,NA,NA,p.Arg124Asp,-4.76,-4.6,1,R454D +urn:mavedb:00000044-a-1#4926,NA,NA,p.Arg124Asp,-4.44,-4.6,2,R454D +urn:mavedb:00000044-a-1#4927,NA,NA,p.Arg124Glu,-3.95,-4.39,1,R454E +urn:mavedb:00000044-a-1#4928,NA,NA,p.Arg124Glu,-4.84,-4.39,2,R454E +urn:mavedb:00000044-a-1#4929,NA,NA,p.Arg124Phe,-4.56,-4.7,1,R454F +urn:mavedb:00000044-a-1#4930,NA,NA,p.Arg124Phe,-4.84,-4.7,2,R454F +urn:mavedb:00000044-a-1#4931,NA,NA,p.Arg124Gly,-4.64,-4.72,1,R454G +urn:mavedb:00000044-a-1#4932,NA,NA,p.Arg124Gly,-4.8,-4.72,2,R454G +urn:mavedb:00000044-a-1#4933,NA,NA,p.Arg124His,-4.76,-4.74,1,R454H +urn:mavedb:00000044-a-1#4934,NA,NA,p.Arg124His,-4.72,-4.74,2,R454H +urn:mavedb:00000044-a-1#4935,NA,NA,p.Arg124Ile,-3.95,-4.39,1,R454I +urn:mavedb:00000044-a-1#4936,NA,NA,p.Arg124Ile,-4.84,-4.39,2,R454I +urn:mavedb:00000044-a-1#4937,NA,NA,p.Arg124Lys,-0.92,-1.12,1,R454K +urn:mavedb:00000044-a-1#4938,NA,NA,p.Arg124Lys,-1.32,-1.12,2,R454K +urn:mavedb:00000044-a-1#4939,NA,NA,p.Arg124Leu,-4.67,-4.73,1,R454L +urn:mavedb:00000044-a-1#4940,NA,NA,p.Arg124Leu,-4.78,-4.73,2,R454L +urn:mavedb:00000044-a-1#6066,NA,NA,p.Gly152Gln,-0.02,0.04,2,G482Q +urn:mavedb:00000044-a-1#6067,NA,NA,p.Gly152Arg,-0.08,-0.1,1,G482R +urn:mavedb:00000044-a-1#6068,NA,NA,p.Gly152Arg,-0.12,-0.1,2,G482R +urn:mavedb:00000044-a-1#6069,NA,NA,p.Gly152Ser,-0.04,-0.08,1,G482S +urn:mavedb:00000044-a-1#6070,NA,NA,p.Gly152Ser,-0.11,-0.08,2,G482S +urn:mavedb:00000044-a-1#6071,NA,NA,p.Gly152Thr,-0.21,-0.21,1,G482T +urn:mavedb:00000044-a-1#6072,NA,NA,p.Gly152Thr,-0.22,-0.21,2,G482T +urn:mavedb:00000044-a-1#6073,NA,NA,p.Gly152Val,-0.41,-0.45,1,G482V +urn:mavedb:00000044-a-1#6074,NA,NA,p.Gly152Val,-0.5,-0.45,2,G482V +urn:mavedb:00000044-a-1#6075,NA,NA,p.Gly152Trp,-0.29,-0.36,1,G482W +urn:mavedb:00000044-a-1#6076,NA,NA,p.Gly152Trp,-0.44,-0.36,2,G482W +urn:mavedb:00000044-a-1#6077,NA,NA,p.Gly152Tyr,-0.15,-0.2,1,G482Y +urn:mavedb:00000044-a-1#6078,NA,NA,p.Gly152Tyr,-0.26,-0.2,2,G482Y +urn:mavedb:00000044-a-1#6079,NA,NA,p.Gly152*,NA,NA,1,G482 +urn:mavedb:00000044-a-1#6080,NA,NA,p.Gly152*,NA,NA,2,G482 +urn:mavedb:00000044-a-1#6081,NA,NA,p.Val153Ala,0,-0.03,1,V483A +urn:mavedb:00000044-a-1#6082,NA,NA,p.Val153Ala,-0.05,-0.03,2,V483A +urn:mavedb:00000044-a-1#6083,NA,NA,p.Val153Cys,-0.07,-0.05,1,V483C +urn:mavedb:00000044-a-1#6084,NA,NA,p.Val153Cys,-0.04,-0.05,2,V483C +urn:mavedb:00000044-a-1#6085,NA,NA,p.Val153Asp,0.03,-0.02,1,V483D +urn:mavedb:00000044-a-1#6086,NA,NA,p.Val153Asp,-0.07,-0.02,2,V483D +urn:mavedb:00000044-a-1#6087,NA,NA,p.Val153Glu,0,-0.03,1,V483E +urn:mavedb:00000044-a-1#6088,NA,NA,p.Val153Glu,-0.06,-0.03,2,V483E +urn:mavedb:00000044-a-1#6089,NA,NA,p.Val153Phe,0.04,-0.01,1,V483F +urn:mavedb:00000044-a-1#6090,NA,NA,p.Val153Phe,-0.06,-0.01,2,V483F +urn:mavedb:00000044-a-1#6091,NA,NA,p.Val153Gly,-0.01,-0.04,1,V483G +urn:mavedb:00000044-a-1#6092,NA,NA,p.Val153Gly,-0.07,-0.04,2,V483G +urn:mavedb:00000044-a-1#6093,NA,NA,p.Val153His,0,0,1,V483H +urn:mavedb:00000044-a-1#6094,NA,NA,p.Val153His,0,0,2,V483H +urn:mavedb:00000044-a-1#6095,NA,NA,p.Val153Ile,-0.01,-0.03,1,V483I +urn:mavedb:00000044-a-1#6096,NA,NA,p.Val153Ile,-0.06,-0.03,2,V483I +urn:mavedb:00000044-a-1#6097,NA,NA,p.Val153Lys,0.1,0.05,1,V483K +urn:mavedb:00000044-a-1#6098,NA,NA,p.Val153Lys,0.01,0.05,2,V483K +urn:mavedb:00000044-a-1#6099,NA,NA,p.Val153Leu,0.07,0.06,1,V483L +urn:mavedb:00000044-a-1#6100,NA,NA,p.Val153Leu,0.06,0.06,2,V483L +urn:mavedb:00000044-a-1#6101,NA,NA,p.Val153Met,0.03,-0.01,1,V483M +urn:mavedb:00000044-a-1#6102,NA,NA,p.Val153Met,-0.05,-0.01,2,V483M +urn:mavedb:00000044-a-1#6103,NA,NA,p.Val153Asn,0.07,0.03,1,V483N +urn:mavedb:00000044-a-1#6104,NA,NA,p.Val153Asn,-0.01,0.03,2,V483N +urn:mavedb:00000044-a-1#6105,NA,NA,p.Val153Pro,-0.49,-0.7,1,V483P +urn:mavedb:00000044-a-1#6106,NA,NA,p.Val153Pro,-0.9,-0.7,2,V483P +urn:mavedb:00000044-a-1#6107,NA,NA,p.Val153Gln,0.03,0.05,1,V483Q +urn:mavedb:00000044-a-1#6108,NA,NA,p.Val153Gln,0.06,0.05,2,V483Q +urn:mavedb:00000044-a-1#6109,NA,NA,p.Val153Arg,0.03,0.05,1,V483R +urn:mavedb:00000044-a-1#6110,NA,NA,p.Val153Arg,0.08,0.05,2,V483R +urn:mavedb:00000044-a-1#6111,NA,NA,p.Val153Ser,-0.08,-0.08,1,V483S +urn:mavedb:00000044-a-1#6112,NA,NA,p.Val153Ser,-0.08,-0.08,2,V483S +urn:mavedb:00000044-a-1#6113,NA,NA,p.Val153Thr,-0.04,-0.17,1,V483T +urn:mavedb:00000044-a-1#6114,NA,NA,p.Val153Thr,-0.3,-0.17,2,V483T +urn:mavedb:00000044-a-1#6115,NA,NA,p.Val153Trp,-0.18,-0.17,1,V483W +urn:mavedb:00000044-a-1#6116,NA,NA,p.Val153Trp,-0.15,-0.17,2,V483W +urn:mavedb:00000044-a-1#6117,NA,NA,p.Val153Tyr,-0.08,-0.05,1,V483Y +urn:mavedb:00000044-a-1#6118,NA,NA,p.Val153Tyr,-0.03,-0.05,2,V483Y +urn:mavedb:00000044-a-1#6119,NA,NA,p.Val153*,NA,NA,1,V483 +urn:mavedb:00000044-a-1#6120,NA,NA,p.Val153*,NA,NA,2,V483 +urn:mavedb:00000044-a-1#6121,NA,NA,p.Glu154Ala,-0.01,-0.07,1,E484A +urn:mavedb:00000044-a-1#6122,NA,NA,p.Glu154Ala,-0.12,-0.07,2,E484A +urn:mavedb:00000044-a-1#6123,NA,NA,p.Glu154Cys,-0.49,-0.52,1,E484C +urn:mavedb:00000044-a-1#6124,NA,NA,p.Glu154Cys,-0.55,-0.52,2,E484C +urn:mavedb:00000044-a-1#6125,NA,NA,p.Glu154Asp,-0.34,-0.38,1,E484D +urn:mavedb:00000044-a-1#6126,NA,NA,p.Glu154Asp,-0.43,-0.38,2,E484D +urn:mavedb:00000044-a-1#6127,NA,NA,p.Glu154Phe,-1.41,-1.43,1,E484F +urn:mavedb:00000044-a-1#6128,NA,NA,p.Glu154Phe,-1.45,-1.43,2,E484F +urn:mavedb:00000044-a-1#6129,NA,NA,p.Glu154Gly,-0.03,-0.06,1,E484G +urn:mavedb:00000044-a-1#6130,NA,NA,p.Glu154Gly,-0.1,-0.06,2,E484G +urn:mavedb:00000044-a-1#6131,NA,NA,p.Glu154His,-0.53,-0.55,1,E484H +urn:mavedb:00000044-a-1#6194,NA,NA,p.Gly155Val,-0.7,-0.67,2,G485V +urn:mavedb:00000044-a-1#6139,NA,NA,p.Glu154Met,-0.24,-0.26,1,E484M +urn:mavedb:00000044-a-1#6195,NA,NA,p.Gly155Trp,-0.53,-0.57,1,G485W +urn:mavedb:00000044-a-1#6140,NA,NA,p.Glu154Met,-0.28,-0.26,2,E484M +urn:mavedb:00000044-a-1#6196,NA,NA,p.Gly155Trp,-0.62,-0.57,2,G485W +urn:mavedb:00000044-a-1#6197,NA,NA,p.Gly155Tyr,-0.63,-0.7,1,G485Y +urn:mavedb:00000044-a-1#6141,NA,NA,p.Glu154Asn,-0.02,-0.08,1,E484N +urn:mavedb:00000044-a-1#6142,NA,NA,p.Glu154Asn,-0.13,-0.08,2,E484N +urn:mavedb:00000044-a-1#6198,NA,NA,p.Gly155Tyr,-0.77,-0.7,2,G485Y +urn:mavedb:00000044-a-1#6143,NA,NA,p.Glu154Pro,-0.44,-0.28,1,E484P +urn:mavedb:00000044-a-1#6199,NA,NA,p.Gly155*,NA,NA,1,G485 +urn:mavedb:00000044-a-1#6200,NA,NA,p.Gly155*,NA,NA,2,G485 +urn:mavedb:00000044-a-1#6201,NA,NA,p.Phe156Ala,-0.3,-0.34,1,F486A +urn:mavedb:00000044-a-1#6240,NA,NA,p.Phe156*,NA,NA,2,F486 +urn:mavedb:00000044-a-1#4941,NA,NA,p.Arg124Met,-4.29,-4.56,1,R454M +urn:mavedb:00000044-a-1#4942,NA,NA,p.Arg124Met,-4.84,-4.56,2,R454M +urn:mavedb:00000044-a-1#4943,NA,NA,p.Arg124Asn,-4.38,-4.14,1,R454N +urn:mavedb:00000044-a-1#4944,NA,NA,p.Arg124Asn,-3.9,-4.14,2,R454N +urn:mavedb:00000044-a-1#4945,NA,NA,p.Arg124Pro,-4.76,-4.8,1,R454P +urn:mavedb:00000044-a-1#4946,NA,NA,p.Arg124Pro,-4.84,-4.8,2,R454P +urn:mavedb:00000044-a-1#4947,NA,NA,p.Arg124Gln,-4.76,-4.8,1,R454Q +urn:mavedb:00000044-a-1#4948,NA,NA,p.Arg124Gln,-4.84,-4.8,2,R454Q +urn:mavedb:00000044-a-1#4949,NA,NA,p.Arg124Ser,-4.08,-4.32,1,R454S +urn:mavedb:00000044-a-1#4950,NA,NA,p.Arg124Ser,-4.56,-4.32,2,R454S +urn:mavedb:00000044-a-1#4951,NA,NA,p.Arg124Thr,-4.21,-4.41,1,R454T +urn:mavedb:00000044-a-1#4952,NA,NA,p.Arg124Thr,-4.61,-4.41,2,R454T +urn:mavedb:00000044-a-1#4953,NA,NA,p.Arg124Val,-4.75,-4.77,1,R454V +urn:mavedb:00000044-a-1#4954,NA,NA,p.Arg124Val,-4.79,-4.77,2,R454V +urn:mavedb:00000044-a-1#4955,NA,NA,p.Arg124Trp,-4.11,-3.9,1,R454W +urn:mavedb:00000044-a-1#4956,NA,NA,p.Arg124Trp,-3.7,-3.9,2,R454W +urn:mavedb:00000044-a-1#4957,NA,NA,p.Arg124Tyr,-4.37,-4.06,1,R454Y +urn:mavedb:00000044-a-1#4958,NA,NA,p.Arg124Tyr,-3.75,-4.06,2,R454Y +urn:mavedb:00000044-a-1#4959,NA,NA,p.Arg124*,NA,NA,1,R454 +urn:mavedb:00000044-a-1#4960,NA,NA,p.Arg124*,NA,NA,2,R454 +urn:mavedb:00000044-a-1#4961,NA,NA,p.Leu125Ala,-0.42,-0.47,1,L455A +urn:mavedb:00000044-a-1#4962,NA,NA,p.Leu125Ala,-0.52,-0.47,2,L455A +urn:mavedb:00000044-a-1#4963,NA,NA,p.Leu125Cys,-0.65,-0.71,1,L455C +urn:mavedb:00000044-a-1#4964,NA,NA,p.Leu125Cys,-0.76,-0.71,2,L455C +urn:mavedb:00000044-a-1#4965,NA,NA,p.Leu125Asp,-2.06,-2.25,1,L455D +urn:mavedb:00000044-a-1#4966,NA,NA,p.Leu125Asp,-2.44,-2.25,2,L455D +urn:mavedb:00000044-a-1#4967,NA,NA,p.Leu125Glu,-2.04,-2.05,1,L455E +urn:mavedb:00000044-a-1#4968,NA,NA,p.Leu125Glu,-2.07,-2.05,2,L455E +urn:mavedb:00000044-a-1#6144,NA,NA,p.Glu154Pro,-0.12,-0.28,2,E484P +urn:mavedb:00000044-a-1#6145,NA,NA,p.Glu154Gln,0.03,0.03,1,E484Q +urn:mavedb:00000044-a-1#6202,NA,NA,p.Phe156Ala,-0.38,-0.34,2,F486A +urn:mavedb:00000044-a-1#6203,NA,NA,p.Phe156Cys,-1.16,-1.2,1,F486C +urn:mavedb:00000044-a-1#6204,NA,NA,p.Phe156Cys,-1.24,-1.2,2,F486C +urn:mavedb:00000044-a-1#6146,NA,NA,p.Glu154Gln,0.03,0.03,2,E484Q +urn:mavedb:00000044-a-1#6147,NA,NA,p.Glu154Arg,0.19,0.15,1,E484R +urn:mavedb:00000044-a-1#6148,NA,NA,p.Glu154Arg,0.11,0.15,2,E484R +urn:mavedb:00000044-a-1#6205,NA,NA,p.Phe156Asp,-1.7,-1.69,1,F486D +urn:mavedb:00000044-a-1#6206,NA,NA,p.Phe156Asp,-1.68,-1.69,2,F486D +urn:mavedb:00000044-a-1#6241,NA,NA,p.Asn157Ala,-1.67,-1.74,1,N487A +urn:mavedb:00000044-a-1#6168,NA,NA,p.Gly155Glu,-0.43,-0.43,2,G485E +urn:mavedb:00000044-a-1#6169,NA,NA,p.Gly155Phe,-0.71,-0.8,1,G485F +urn:mavedb:00000044-a-1#6242,NA,NA,p.Asn157Ala,-1.8,-1.74,2,N487A +urn:mavedb:00000044-a-1#6243,NA,NA,p.Asn157Cys,-2.31,-2.41,1,N487C +urn:mavedb:00000044-a-1#6255,NA,NA,p.Asn157Ile,-2.78,-2.77,1,N487I +urn:mavedb:00000044-a-1#6256,NA,NA,p.Asn157Ile,-2.77,-2.77,2,N487I +urn:mavedb:00000044-a-1#6149,NA,NA,p.Glu154Ser,-0.05,-0.02,1,E484S +urn:mavedb:00000044-a-1#6257,NA,NA,p.Asn157Lys,-2.21,-2.3,1,N487K +urn:mavedb:00000044-a-1#6258,NA,NA,p.Asn157Lys,-2.38,-2.3,2,N487K +urn:mavedb:00000044-a-1#6259,NA,NA,p.Asn157Leu,-2.15,-2.2,1,N487L +urn:mavedb:00000044-a-1#6260,NA,NA,p.Asn157Leu,-2.25,-2.2,2,N487L +urn:mavedb:00000044-a-1#6261,NA,NA,p.Asn157Met,-2.1,-2.12,1,N487M +urn:mavedb:00000044-a-1#6262,NA,NA,p.Asn157Met,-2.13,-2.12,2,N487M +urn:mavedb:00000044-a-1#6263,NA,NA,p.Asn157Pro,-2.63,-2.64,1,N487P +urn:mavedb:00000044-a-1#6132,NA,NA,p.Glu154His,-0.58,-0.55,2,E484H +urn:mavedb:00000044-a-1#6133,NA,NA,p.Glu154Ile,-0.68,-0.64,1,E484I +urn:mavedb:00000044-a-1#6264,NA,NA,p.Asn157Pro,-2.64,-2.64,2,N487P +urn:mavedb:00000044-a-1#6265,NA,NA,p.Asn157Gln,-2.34,-2.09,1,N487Q +urn:mavedb:00000044-a-1#6266,NA,NA,p.Asn157Gln,-1.85,-2.09,2,N487Q +urn:mavedb:00000044-a-1#6181,NA,NA,p.Gly155Asn,-0.33,-0.43,1,G485N +urn:mavedb:00000044-a-1#6134,NA,NA,p.Glu154Ile,-0.6,-0.64,2,E484I +urn:mavedb:00000044-a-1#6135,NA,NA,p.Glu154Lys,0.09,0.06,1,E484K +urn:mavedb:00000044-a-1#6136,NA,NA,p.Glu154Lys,0.03,0.06,2,E484K +urn:mavedb:00000044-a-1#6182,NA,NA,p.Gly155Asn,-0.52,-0.43,2,G485N +urn:mavedb:00000044-a-1#6183,NA,NA,p.Gly155Pro,-1.55,-1.53,1,G485P +urn:mavedb:00000044-a-1#6184,NA,NA,p.Gly155Pro,-1.51,-1.53,2,G485P +urn:mavedb:00000044-a-1#6185,NA,NA,p.Gly155Gln,-0.15,-0.11,1,G485Q +urn:mavedb:00000044-a-1#6186,NA,NA,p.Gly155Gln,-0.07,-0.11,2,G485Q +urn:mavedb:00000044-a-1#6187,NA,NA,p.Gly155Arg,-0.14,-0.18,1,G485R +urn:mavedb:00000044-a-1#6137,NA,NA,p.Glu154Leu,-0.71,-0.71,1,E484L +urn:mavedb:00000044-a-1#6138,NA,NA,p.Glu154Leu,-0.72,-0.71,2,E484L +urn:mavedb:00000044-a-1#6188,NA,NA,p.Gly155Arg,-0.23,-0.18,2,G485R +urn:mavedb:00000044-a-1#6189,NA,NA,p.Gly155Ser,-0.18,-0.2,1,G485S +urn:mavedb:00000044-a-1#6190,NA,NA,p.Gly155Ser,-0.22,-0.2,2,G485S +urn:mavedb:00000044-a-1#6191,NA,NA,p.Gly155Thr,-0.17,-0.22,1,G485T +urn:mavedb:00000044-a-1#6192,NA,NA,p.Gly155Thr,-0.26,-0.22,2,G485T +urn:mavedb:00000044-a-1#6150,NA,NA,p.Glu154Ser,0.02,-0.02,2,E484S +urn:mavedb:00000044-a-1#6151,NA,NA,p.Glu154Thr,0.05,0.05,1,E484T +urn:mavedb:00000044-a-1#6152,NA,NA,p.Glu154Thr,0.04,0.05,2,E484T +urn:mavedb:00000044-a-1#6153,NA,NA,p.Glu154Val,-0.63,-0.65,1,E484V +urn:mavedb:00000044-a-1#6154,NA,NA,p.Glu154Val,-0.68,-0.65,2,E484V +urn:mavedb:00000044-a-1#6155,NA,NA,p.Glu154Trp,-0.71,-0.78,1,E484W +urn:mavedb:00000044-a-1#6156,NA,NA,p.Glu154Trp,-0.84,-0.78,2,E484W +urn:mavedb:00000044-a-1#6157,NA,NA,p.Glu154Tyr,-1.46,-1.51,1,E484Y +urn:mavedb:00000044-a-1#6158,NA,NA,p.Glu154Tyr,-1.57,-1.51,2,E484Y +urn:mavedb:00000044-a-1#6159,NA,NA,p.Glu154*,NA,NA,1,E484 +urn:mavedb:00000044-a-1#6160,NA,NA,p.Glu154*,NA,NA,2,E484 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+urn:mavedb:00000044-a-1#6208,NA,NA,p.Phe156Glu,-1.61,-1.63,2,F486E +urn:mavedb:00000044-a-1#6209,NA,NA,p.Phe156Gly,-0.85,-0.77,1,F486G +urn:mavedb:00000044-a-1#6210,NA,NA,p.Phe156Gly,-0.68,-0.77,2,F486G +urn:mavedb:00000044-a-1#6211,NA,NA,p.Phe156His,-0.43,-0.42,1,F486H +urn:mavedb:00000044-a-1#6212,NA,NA,p.Phe156His,-0.4,-0.42,2,F486H +urn:mavedb:00000044-a-1#6213,NA,NA,p.Phe156Ile,-0.35,-0.38,1,F486I +urn:mavedb:00000044-a-1#6214,NA,NA,p.Phe156Ile,-0.42,-0.38,2,F486I +urn:mavedb:00000044-a-1#6215,NA,NA,p.Phe156Lys,-0.58,-0.62,1,F486K +urn:mavedb:00000044-a-1#6216,NA,NA,p.Phe156Lys,-0.66,-0.62,2,F486K +urn:mavedb:00000044-a-1#6217,NA,NA,p.Phe156Leu,-0.41,-0.47,1,F486L +urn:mavedb:00000044-a-1#6218,NA,NA,p.Phe156Leu,-0.54,-0.47,2,F486L +urn:mavedb:00000044-a-1#6219,NA,NA,p.Phe156Met,-0.49,-0.53,1,F486M +urn:mavedb:00000044-a-1#6220,NA,NA,p.Phe156Met,-0.57,-0.53,2,F486M +urn:mavedb:00000044-a-1#6221,NA,NA,p.Phe156Asn,-0.74,-0.82,1,F486N +urn:mavedb:00000044-a-1#6222,NA,NA,p.Phe156Asn,-0.9,-0.82,2,F486N +urn:mavedb:00000044-a-1#6223,NA,NA,p.Phe156Pro,-0.1,-0.18,1,F486P +urn:mavedb:00000044-a-1#6224,NA,NA,p.Phe156Pro,-0.27,-0.18,2,F486P +urn:mavedb:00000044-a-1#6225,NA,NA,p.Phe156Gln,-0.65,-0.72,1,F486Q +urn:mavedb:00000044-a-1#6226,NA,NA,p.Phe156Gln,-0.79,-0.72,2,F486Q +urn:mavedb:00000044-a-1#6275,NA,NA,p.Asn157Trp,-2.28,-2.39,1,N487W +urn:mavedb:00000044-a-1#6276,NA,NA,p.Asn157Trp,-2.5,-2.39,2,N487W +urn:mavedb:00000044-a-1#6277,NA,NA,p.Asn157Tyr,-2.37,-2.3,1,N487Y +urn:mavedb:00000044-a-1#6278,NA,NA,p.Asn157Tyr,-2.22,-2.3,2,N487Y +urn:mavedb:00000044-a-1#6279,NA,NA,p.Asn157*,NA,NA,1,N487 +urn:mavedb:00000044-a-1#6291,NA,NA,p.Cys158His,-3.55,-3.61,1,C488H +urn:mavedb:00000044-a-1#6390,NA,NA,p.Phe160Ser,-0.02,0,2,F490S +urn:mavedb:00000044-a-1#6391,NA,NA,p.Phe160Thr,0.03,-0.04,1,F490T +urn:mavedb:00000044-a-1#6292,NA,NA,p.Cys158His,-3.67,-3.61,2,C488H +urn:mavedb:00000044-a-1#6293,NA,NA,p.Cys158Ile,-4.76,-4.79,1,C488I +urn:mavedb:00000044-a-1#6294,NA,NA,p.Cys158Ile,-4.82,-4.79,2,C488I +urn:mavedb:00000044-a-1#6295,NA,NA,p.Cys158Lys,-2.96,-2.93,1,C488K +urn:mavedb:00000044-a-1#6296,NA,NA,p.Cys158Lys,-2.9,-2.93,2,C488K +urn:mavedb:00000044-a-1#6297,NA,NA,p.Cys158Leu,-4.26,-4.34,1,C488L +urn:mavedb:00000044-a-1#6298,NA,NA,p.Cys158Leu,-4.43,-4.34,2,C488L +urn:mavedb:00000044-a-1#6299,NA,NA,p.Cys158Met,-3.6,-3.61,1,C488M +urn:mavedb:00000044-a-1#6300,NA,NA,p.Cys158Met,-3.63,-3.61,2,C488M +urn:mavedb:00000044-a-1#6301,NA,NA,p.Cys158Asn,-3.04,-3.09,1,C488N +urn:mavedb:00000044-a-1#6302,NA,NA,p.Cys158Asn,-3.15,-3.09,2,C488N +urn:mavedb:00000044-a-1#6392,NA,NA,p.Phe160Thr,-0.12,-0.04,2,F490T +urn:mavedb:00000044-a-1#6393,NA,NA,p.Phe160Val,-0.05,-0.08,1,F490V +urn:mavedb:00000044-a-1#6303,NA,NA,p.Cys158Pro,-4.72,-4.78,1,C488P +urn:mavedb:00000044-a-1#6304,NA,NA,p.Cys158Pro,-4.84,-4.78,2,C488P +urn:mavedb:00000044-a-1#6305,NA,NA,p.Cys158Gln,-2.89,-2.84,1,C488Q +urn:mavedb:00000044-a-1#6306,NA,NA,p.Cys158Gln,-2.78,-2.84,2,C488Q +urn:mavedb:00000044-a-1#6307,NA,NA,p.Cys158Arg,-2.83,-2.84,1,C488R +urn:mavedb:00000044-a-1#6308,NA,NA,p.Cys158Arg,-2.86,-2.84,2,C488R +urn:mavedb:00000044-a-1#6309,NA,NA,p.Cys158Ser,-2.72,-2.84,1,C488S +urn:mavedb:00000044-a-1#6310,NA,NA,p.Cys158Ser,-2.96,-2.84,2,C488S +urn:mavedb:00000044-a-1#6311,NA,NA,p.Cys158Thr,-3.27,-3.34,1,C488T +urn:mavedb:00000044-a-1#6312,NA,NA,p.Cys158Thr,-3.4,-3.34,2,C488T +urn:mavedb:00000044-a-1#6313,NA,NA,p.Cys158Val,-4.63,-4.55,1,C488V +urn:mavedb:00000044-a-1#5008,NA,NA,p.Phe126Glu,-2.39,-2.45,2,F456E +urn:mavedb:00000044-a-1#5009,NA,NA,p.Phe126Gly,-2.16,-2.22,1,F456G +urn:mavedb:00000044-a-1#5010,NA,NA,p.Phe126Gly,-2.28,-2.22,2,F456G +urn:mavedb:00000044-a-1#5011,NA,NA,p.Phe126His,-0.64,-0.69,1,F456H +urn:mavedb:00000044-a-1#5012,NA,NA,p.Phe126His,-0.73,-0.69,2,F456H +urn:mavedb:00000044-a-1#5013,NA,NA,p.Phe126Ile,-1.12,-1.21,1,F456I +urn:mavedb:00000044-a-1#5014,NA,NA,p.Phe126Ile,-1.3,-1.21,2,F456I +urn:mavedb:00000044-a-1#5015,NA,NA,p.Phe126Lys,-0.86,-1.38,1,F456K +urn:mavedb:00000044-a-1#5016,NA,NA,p.Phe126Lys,-1.89,-1.38,2,F456K +urn:mavedb:00000044-a-1#5017,NA,NA,p.Phe126Leu,-0.05,-0.11,1,F456L +urn:mavedb:00000044-a-1#5018,NA,NA,p.Phe126Leu,-0.18,-0.11,2,F456L +urn:mavedb:00000044-a-1#5019,NA,NA,p.Phe126Met,-0.15,-0.22,1,F456M +urn:mavedb:00000044-a-1#5020,NA,NA,p.Phe126Met,-0.28,-0.22,2,F456M +urn:mavedb:00000044-a-1#5021,NA,NA,p.Phe126Asn,-2.34,-2.38,1,F456N +urn:mavedb:00000044-a-1#5022,NA,NA,p.Phe126Asn,-2.42,-2.38,2,F456N +urn:mavedb:00000044-a-1#5023,NA,NA,p.Phe126Pro,-2.75,-2.69,1,F456P +urn:mavedb:00000044-a-1#5024,NA,NA,p.Phe126Pro,-2.62,-2.69,2,F456P +urn:mavedb:00000044-a-1#5025,NA,NA,p.Phe126Gln,-2.07,-2.07,1,F456Q +urn:mavedb:00000044-a-1#5026,NA,NA,p.Phe126Gln,-2.06,-2.07,2,F456Q +urn:mavedb:00000044-a-1#5027,NA,NA,p.Phe126Arg,-2.11,-2.08,1,F456R +urn:mavedb:00000044-a-1#5028,NA,NA,p.Phe126Arg,-2.04,-2.08,2,F456R +urn:mavedb:00000044-a-1#5029,NA,NA,p.Phe126Ser,-2.4,-2.42,1,F456S +urn:mavedb:00000044-a-1#5030,NA,NA,p.Phe126Ser,-2.45,-2.42,2,F456S +urn:mavedb:00000044-a-1#5031,NA,NA,p.Phe126Thr,-1.54,-1.65,1,F456T +urn:mavedb:00000044-a-1#5032,NA,NA,p.Phe126Thr,-1.76,-1.65,2,F456T +urn:mavedb:00000044-a-1#5033,NA,NA,p.Phe126Val,-0.58,-0.61,1,F456V +urn:mavedb:00000044-a-1#5034,NA,NA,p.Phe126Val,-0.65,-0.61,2,F456V +urn:mavedb:00000044-a-1#5035,NA,NA,p.Phe126Trp,-0.91,-1.01,1,F456W +urn:mavedb:00000044-a-1#5036,NA,NA,p.Phe126Trp,-1.1,-1.01,2,F456W +urn:mavedb:00000044-a-1#5037,NA,NA,p.Phe126Tyr,-1.43,-1.5,1,F456Y +urn:mavedb:00000044-a-1#5038,NA,NA,p.Phe126Tyr,-1.56,-1.5,2,F456Y +urn:mavedb:00000044-a-1#5039,NA,NA,p.Phe126*,NA,NA,1,F456 +urn:mavedb:00000044-a-1#5040,NA,NA,p.Phe126*,NA,NA,2,F456 +urn:mavedb:00000044-a-1#5041,NA,NA,p.Arg127Ala,-0.43,-0.45,1,R457A +urn:mavedb:00000044-a-1#5042,NA,NA,p.Arg127Ala,-0.46,-0.45,2,R457A +urn:mavedb:00000044-a-1#5043,NA,NA,p.Arg127Cys,-1.86,-2.15,1,R457C +urn:mavedb:00000044-a-1#3147,NA,NA,p.Gln79Arg,-0.7,-0.78,1,Q409R +urn:mavedb:00000044-a-1#6314,NA,NA,p.Cys158Val,-4.46,-4.55,2,C488V +urn:mavedb:00000044-a-1#6315,NA,NA,p.Cys158Trp,-4.44,-4.61,1,C488W +urn:mavedb:00000044-a-1#6329,NA,NA,p.Tyr159Phe,-0.94,-0.95,1,Y489F +urn:mavedb:00000044-a-1#6330,NA,NA,p.Tyr159Phe,-0.95,-0.95,2,Y489F +urn:mavedb:00000044-a-1#6331,NA,NA,p.Tyr159Gly,-4.26,-4.32,1,Y489G +urn:mavedb:00000044-a-1#6332,NA,NA,p.Tyr159Gly,-4.37,-4.32,2,Y489G +urn:mavedb:00000044-a-1#6333,NA,NA,p.Tyr159His,-0.61,-0.66,1,Y489H +urn:mavedb:00000044-a-1#6334,NA,NA,p.Tyr159His,-0.72,-0.66,2,Y489H +urn:mavedb:00000044-a-1#6335,NA,NA,p.Tyr159Ile,-2.13,-2.22,1,Y489I +urn:mavedb:00000044-a-1#6336,NA,NA,p.Tyr159Ile,-2.31,-2.22,2,Y489I +urn:mavedb:00000044-a-1#6337,NA,NA,p.Tyr159Lys,-4.51,-4.33,1,Y489K +urn:mavedb:00000044-a-1#6338,NA,NA,p.Tyr159Lys,-4.16,-4.33,2,Y489K +urn:mavedb:00000044-a-1#6339,NA,NA,p.Tyr159Leu,-2.25,-2.2,1,Y489L +urn:mavedb:00000044-a-1#6340,NA,NA,p.Tyr159Leu,-2.15,-2.2,2,Y489L +urn:mavedb:00000044-a-1#6245,NA,NA,p.Asn157Asp,-1.01,-1.08,1,N487D +urn:mavedb:00000044-a-1#6246,NA,NA,p.Asn157Asp,-1.16,-1.08,2,N487D +urn:mavedb:00000044-a-1#6247,NA,NA,p.Asn157Glu,-2.07,-2.06,1,N487E +urn:mavedb:00000044-a-1#6248,NA,NA,p.Asn157Glu,-2.06,-2.06,2,N487E +urn:mavedb:00000044-a-1#6249,NA,NA,p.Asn157Phe,-2.23,-2.29,1,N487F +urn:mavedb:00000044-a-1#6250,NA,NA,p.Asn157Phe,-2.35,-2.29,2,N487F +urn:mavedb:00000044-a-1#6251,NA,NA,p.Asn157Gly,-1.53,-1.59,1,N487G +urn:mavedb:00000044-a-1#6252,NA,NA,p.Asn157Gly,-1.66,-1.59,2,N487G +urn:mavedb:00000044-a-1#6344,NA,NA,p.Tyr159Asn,-2.71,-2.57,2,Y489N +urn:mavedb:00000044-a-1#6345,NA,NA,p.Tyr159Pro,-2.18,-2.26,1,Y489P +urn:mavedb:00000044-a-1#6253,NA,NA,p.Asn157His,-1.83,-1.87,1,N487H +urn:mavedb:00000044-a-1#6254,NA,NA,p.Asn157His,-1.92,-1.87,2,N487H +urn:mavedb:00000044-a-1#6244,NA,NA,p.Asn157Cys,-2.5,-2.41,2,N487C +urn:mavedb:00000044-a-1#6341,NA,NA,p.Tyr159Met,-1.93,-1.98,1,Y489M +urn:mavedb:00000044-a-1#6280,NA,NA,p.Asn157*,NA,NA,2,N487 +urn:mavedb:00000044-a-1#6281,NA,NA,p.Cys158Ala,-2.97,-2.97,1,C488A +urn:mavedb:00000044-a-1#6282,NA,NA,p.Cys158Ala,-2.97,-2.97,2,C488A +urn:mavedb:00000044-a-1#6283,NA,NA,p.Cys158Asp,-4.3,-4.54,1,C488D +urn:mavedb:00000044-a-1#6284,NA,NA,p.Cys158Asp,-4.77,-4.54,2,C488D +urn:mavedb:00000044-a-1#6285,NA,NA,p.Cys158Glu,-3.59,-3.57,1,C488E +urn:mavedb:00000044-a-1#6286,NA,NA,p.Cys158Glu,-3.54,-3.57,2,C488E +urn:mavedb:00000044-a-1#6287,NA,NA,p.Cys158Phe,-4.66,-4.75,1,C488F +urn:mavedb:00000044-a-1#6288,NA,NA,p.Cys158Phe,-4.84,-4.75,2,C488F +urn:mavedb:00000044-a-1#6289,NA,NA,p.Cys158Gly,-4.76,-4.3,1,C488G +urn:mavedb:00000044-a-1#6290,NA,NA,p.Cys158Gly,-3.84,-4.3,2,C488G +urn:mavedb:00000044-a-1#6346,NA,NA,p.Tyr159Pro,-2.34,-2.26,2,Y489P +urn:mavedb:00000044-a-1#6347,NA,NA,p.Tyr159Gln,-2.17,-2.2,1,Y489Q +urn:mavedb:00000044-a-1#6316,NA,NA,p.Cys158Trp,-4.79,-4.61,2,C488W +urn:mavedb:00000044-a-1#6317,NA,NA,p.Cys158Tyr,-4.53,-4.69,1,C488Y +urn:mavedb:00000044-a-1#6318,NA,NA,p.Cys158Tyr,-4.84,-4.69,2,C488Y +urn:mavedb:00000044-a-1#6319,NA,NA,p.Cys158*,NA,NA,1,C488 +urn:mavedb:00000044-a-1#6320,NA,NA,p.Cys158*,NA,NA,2,C488 +urn:mavedb:00000044-a-1#6321,NA,NA,p.Tyr159Ala,-2.37,-2.46,1,Y489A +urn:mavedb:00000044-a-1#6322,NA,NA,p.Tyr159Ala,-2.56,-2.46,2,Y489A +urn:mavedb:00000044-a-1#6323,NA,NA,p.Tyr159Cys,-2.76,-3.24,1,Y489C +urn:mavedb:00000044-a-1#6324,NA,NA,p.Tyr159Cys,-3.73,-3.24,2,Y489C +urn:mavedb:00000044-a-1#6325,NA,NA,p.Tyr159Asp,-3.42,-3.37,1,Y489D +urn:mavedb:00000044-a-1#6326,NA,NA,p.Tyr159Asp,-3.31,-3.37,2,Y489D +urn:mavedb:00000044-a-1#6327,NA,NA,p.Tyr159Glu,-4.09,-3.98,1,Y489E +urn:mavedb:00000044-a-1#6328,NA,NA,p.Tyr159Glu,-3.87,-3.98,2,Y489E +urn:mavedb:00000044-a-1#6342,NA,NA,p.Tyr159Met,-2.02,-1.98,2,Y489M +urn:mavedb:00000044-a-1#6343,NA,NA,p.Tyr159Asn,-2.42,-2.57,1,Y489N +urn:mavedb:00000044-a-1#6365,NA,NA,p.Phe160Asp,-0.04,-0.08,1,F490D +urn:mavedb:00000044-a-1#6366,NA,NA,p.Phe160Asp,-0.11,-0.08,2,F490D +urn:mavedb:00000044-a-1#6383,NA,NA,p.Phe160Pro,-0.04,-0.09,1,F490P +urn:mavedb:00000044-a-1#6367,NA,NA,p.Phe160Glu,-0.11,-0.12,1,F490E +urn:mavedb:00000044-a-1#6368,NA,NA,p.Phe160Glu,-0.12,-0.12,2,F490E +urn:mavedb:00000044-a-1#6369,NA,NA,p.Phe160Gly,-0.03,-0.08,1,F490G +urn:mavedb:00000044-a-1#6384,NA,NA,p.Phe160Pro,-0.14,-0.09,2,F490P +urn:mavedb:00000044-a-1#6385,NA,NA,p.Phe160Gln,-0.01,-0.02,1,F490Q +urn:mavedb:00000044-a-1#6370,NA,NA,p.Phe160Gly,-0.13,-0.08,2,F490G +urn:mavedb:00000044-a-1#6371,NA,NA,p.Phe160His,-0.04,-0.05,1,F490H +urn:mavedb:00000044-a-1#6372,NA,NA,p.Phe160His,-0.06,-0.05,2,F490H +urn:mavedb:00000044-a-1#6373,NA,NA,p.Phe160Ile,-0.14,-0.16,1,F490I +urn:mavedb:00000044-a-1#6374,NA,NA,p.Phe160Ile,-0.18,-0.16,2,F490I +urn:mavedb:00000044-a-1#6375,NA,NA,p.Phe160Lys,0.1,0.09,1,F490K +urn:mavedb:00000044-a-1#6386,NA,NA,p.Phe160Gln,-0.04,-0.02,2,F490Q +urn:mavedb:00000044-a-1#6387,NA,NA,p.Phe160Arg,-0.03,0.01,1,F490R +urn:mavedb:00000044-a-1#6352,NA,NA,p.Tyr159Ser,-4.84,-4.8,2,Y489S +urn:mavedb:00000044-a-1#6353,NA,NA,p.Tyr159Thr,-4.6,-4.61,1,Y489T +urn:mavedb:00000044-a-1#6354,NA,NA,p.Tyr159Thr,-4.62,-4.61,2,Y489T +urn:mavedb:00000044-a-1#6355,NA,NA,p.Tyr159Val,-2.08,-2.15,1,Y489V +urn:mavedb:00000044-a-1#6356,NA,NA,p.Tyr159Val,-2.22,-2.15,2,Y489V +urn:mavedb:00000044-a-1#6357,NA,NA,p.Tyr159Trp,-0.63,-0.68,1,Y489W +urn:mavedb:00000044-a-1#6358,NA,NA,p.Tyr159Trp,-0.74,-0.68,2,Y489W +urn:mavedb:00000044-a-1#6359,NA,NA,p.Tyr159*,NA,NA,1,Y489 +urn:mavedb:00000044-a-1#6360,NA,NA,p.Tyr159*,NA,NA,2,Y489 +urn:mavedb:00000044-a-1#6361,NA,NA,p.Phe160Ala,0.01,0.03,1,F490A +urn:mavedb:00000044-a-1#6362,NA,NA,p.Phe160Ala,0.05,0.03,2,F490A +urn:mavedb:00000044-a-1#6363,NA,NA,p.Phe160Cys,-0.1,-0.11,1,F490C +urn:mavedb:00000044-a-1#6364,NA,NA,p.Phe160Cys,-0.12,-0.11,2,F490C +urn:mavedb:00000044-a-1#6376,NA,NA,p.Phe160Lys,0.08,0.09,2,F490K +urn:mavedb:00000044-a-1#6377,NA,NA,p.Phe160Leu,-0.04,-0.11,1,F490L +urn:mavedb:00000044-a-1#6378,NA,NA,p.Phe160Leu,-0.17,-0.11,2,F490L +urn:mavedb:00000044-a-1#6379,NA,NA,p.Phe160Met,-0.02,-0.03,1,F490M +urn:mavedb:00000044-a-1#6380,NA,NA,p.Phe160Met,-0.04,-0.03,2,F490M +urn:mavedb:00000044-a-1#6381,NA,NA,p.Phe160Asn,0.04,0.02,1,F490N +urn:mavedb:00000044-a-1#6382,NA,NA,p.Phe160Asn,0,0.02,2,F490N +urn:mavedb:00000044-a-1#6394,NA,NA,p.Phe160Val,-0.11,-0.08,2,F490V +urn:mavedb:00000044-a-1#6395,NA,NA,p.Phe160Trp,-0.06,-0.05,1,F490W +urn:mavedb:00000044-a-1#6396,NA,NA,p.Phe160Trp,-0.04,-0.05,2,F490W +urn:mavedb:00000044-a-1#6397,NA,NA,p.Phe160Tyr,0.07,0.06,1,F490Y +urn:mavedb:00000044-a-1#6398,NA,NA,p.Phe160Tyr,0.06,0.06,2,F490Y +urn:mavedb:00000044-a-1#6399,NA,NA,p.Phe160*,NA,NA,1,F490 +urn:mavedb:00000044-a-1#6400,NA,NA,p.Phe160*,NA,NA,2,F490 +urn:mavedb:00000044-a-1#6401,NA,NA,p.Pro161Ala,-0.4,-0.45,1,P491A +urn:mavedb:00000044-a-1#6402,NA,NA,p.Pro161Ala,-0.51,-0.45,2,P491A +urn:mavedb:00000044-a-1#6403,NA,NA,p.Pro161Cys,-1.46,-1.45,1,P491C +urn:mavedb:00000044-a-1#6404,NA,NA,p.Pro161Cys,-1.44,-1.45,2,P491C +urn:mavedb:00000044-a-1#6405,NA,NA,p.Pro161Asp,-2.23,-2.34,1,P491D +urn:mavedb:00000044-a-1#6406,NA,NA,p.Pro161Asp,-2.46,-2.34,2,P491D +urn:mavedb:00000044-a-1#6407,NA,NA,p.Pro161Glu,-0.68,-0.71,1,P491E +urn:mavedb:00000044-a-1#6408,NA,NA,p.Pro161Glu,-0.74,-0.71,2,P491E +urn:mavedb:00000044-a-1#6409,NA,NA,p.Pro161Phe,-4.76,-4.75,1,P491F +urn:mavedb:00000044-a-1#6410,NA,NA,p.Pro161Phe,-4.74,-4.75,2,P491F +urn:mavedb:00000044-a-1#6411,NA,NA,p.Pro161Gly,-0.82,-0.93,1,P491G +urn:mavedb:00000044-a-1#6412,NA,NA,p.Pro161Gly,-1.04,-0.93,2,P491G +urn:mavedb:00000044-a-1#6413,NA,NA,p.Pro161His,-4.27,-3.76,1,P491H +urn:mavedb:00000044-a-1#6414,NA,NA,p.Pro161His,-3.26,-3.76,2,P491H +urn:mavedb:00000044-a-1#6415,NA,NA,p.Pro161Ile,-3.71,-3.99,1,P491I +urn:mavedb:00000044-a-1#6416,NA,NA,p.Pro161Ile,-4.26,-3.99,2,P491I +urn:mavedb:00000044-a-1#6417,NA,NA,p.Pro161Lys,-4.73,-4.39,1,P491K +urn:mavedb:00000044-a-1#6418,NA,NA,p.Pro161Lys,-4.05,-4.39,2,P491K +urn:mavedb:00000044-a-1#6419,NA,NA,p.Pro161Leu,-4.71,-4.65,1,P491L +urn:mavedb:00000044-a-1#6420,NA,NA,p.Pro161Leu,-4.59,-4.65,2,P491L +urn:mavedb:00000044-a-1#6421,NA,NA,p.Pro161Met,-2.09,-2.02,1,P491M +urn:mavedb:00000044-a-1#6422,NA,NA,p.Pro161Met,-1.96,-2.02,2,P491M +urn:mavedb:00000044-a-1#6423,NA,NA,p.Pro161Asn,-1.94,-2.05,1,P491N +urn:mavedb:00000044-a-1#6424,NA,NA,p.Pro161Asn,-2.16,-2.05,2,P491N +urn:mavedb:00000044-a-1#6425,NA,NA,p.Pro161Gln,-1.39,-1.34,1,P491Q +urn:mavedb:00000044-a-1#6426,NA,NA,p.Pro161Gln,-1.29,-1.34,2,P491Q +urn:mavedb:00000044-a-1#6427,NA,NA,p.Pro161Arg,-4.76,-4.8,1,P491R +urn:mavedb:00000044-a-1#6428,NA,NA,p.Pro161Arg,-4.84,-4.8,2,P491R +urn:mavedb:00000044-a-1#6429,NA,NA,p.Pro161Ser,-0.49,-0.57,1,P491S +urn:mavedb:00000044-a-1#6430,NA,NA,p.Pro161Ser,-0.65,-0.57,2,P491S +urn:mavedb:00000044-a-1#6431,NA,NA,p.Pro161Thr,-1.5,-1.58,1,P491T +urn:mavedb:00000044-a-1#6432,NA,NA,p.Pro161Thr,-1.66,-1.58,2,P491T +urn:mavedb:00000044-a-1#6433,NA,NA,p.Pro161Val,-1.62,-1.77,1,P491V +urn:mavedb:00000044-a-1#6434,NA,NA,p.Pro161Val,-1.93,-1.77,2,P491V +urn:mavedb:00000044-a-1#6435,NA,NA,p.Pro161Trp,-4.15,-4.49,1,P491W +urn:mavedb:00000044-a-1#6436,NA,NA,p.Pro161Trp,-4.84,-4.49,2,P491W +urn:mavedb:00000044-a-1#6437,NA,NA,p.Pro161Tyr,-4.76,-4.8,1,P491Y +urn:mavedb:00000044-a-1#6438,NA,NA,p.Pro161Tyr,-4.84,-4.8,2,P491Y +urn:mavedb:00000044-a-1#6439,NA,NA,p.Pro161*,NA,NA,1,P491 +urn:mavedb:00000044-a-1#6440,NA,NA,p.Pro161*,NA,NA,2,P491 +urn:mavedb:00000044-a-1#6441,NA,NA,p.Leu162Ala,-3.65,-4.06,1,L492A +urn:mavedb:00000044-a-1#6442,NA,NA,p.Leu162Ala,-4.47,-4.06,2,L492A +urn:mavedb:00000044-a-1#6443,NA,NA,p.Leu162Cys,-0.8,-0.77,1,L492C +urn:mavedb:00000044-a-1#6444,NA,NA,p.Leu162Cys,-0.74,-0.77,2,L492C +urn:mavedb:00000044-a-1#6445,NA,NA,p.Leu162Asp,-4.76,-4.15,1,L492D +urn:mavedb:00000044-a-1#6446,NA,NA,p.Leu162Asp,-3.55,-4.15,2,L492D +urn:mavedb:00000044-a-1#6447,NA,NA,p.Leu162Glu,-3,-3.08,1,L492E +urn:mavedb:00000044-a-1#6448,NA,NA,p.Leu162Glu,-3.16,-3.08,2,L492E +urn:mavedb:00000044-a-1#6449,NA,NA,p.Leu162Phe,-0.45,-0.52,1,L492F +urn:mavedb:00000044-a-1#6450,NA,NA,p.Leu162Phe,-0.58,-0.52,2,L492F +urn:mavedb:00000044-a-1#6451,NA,NA,p.Leu162Gly,-3.97,-4.17,1,L492G +urn:mavedb:00000044-a-1#6452,NA,NA,p.Leu162Gly,-4.37,-4.17,2,L492G +urn:mavedb:00000044-a-1#6453,NA,NA,p.Leu162His,-1.15,-1.25,1,L492H +urn:mavedb:00000044-a-1#6454,NA,NA,p.Leu162His,-1.35,-1.25,2,L492H +urn:mavedb:00000044-a-1#6455,NA,NA,p.Leu162Ile,0.03,0.03,1,L492I +urn:mavedb:00000044-a-1#6456,NA,NA,p.Leu162Ile,0.02,0.03,2,L492I +urn:mavedb:00000044-a-1#6457,NA,NA,p.Leu162Lys,-1.44,-1.52,1,L492K +urn:mavedb:00000044-a-1#6458,NA,NA,p.Leu162Lys,-1.6,-1.52,2,L492K +urn:mavedb:00000044-a-1#6459,NA,NA,p.Leu162Met,-0.16,-0.27,1,L492M +urn:mavedb:00000044-a-1#6460,NA,NA,p.Leu162Met,-0.38,-0.27,2,L492M +urn:mavedb:00000044-a-1#6461,NA,NA,p.Leu162Asn,-1.14,-1.21,1,L492N +urn:mavedb:00000044-a-1#6462,NA,NA,p.Leu162Asn,-1.27,-1.21,2,L492N +urn:mavedb:00000044-a-1#6532,NA,NA,p.Ser164Gly,-0.38,-0.34,2,S494G +urn:mavedb:00000044-a-1#6463,NA,NA,p.Leu162Pro,-4.72,-4.78,1,L492P +urn:mavedb:00000044-a-1#6464,NA,NA,p.Leu162Pro,-4.84,-4.78,2,L492P +urn:mavedb:00000044-a-1#6465,NA,NA,p.Leu162Gln,-1.13,-1.19,1,L492Q +urn:mavedb:00000044-a-1#6466,NA,NA,p.Leu162Gln,-1.25,-1.19,2,L492Q +urn:mavedb:00000044-a-1#6467,NA,NA,p.Leu162Arg,-1.25,-1.21,1,L492R +urn:mavedb:00000044-a-1#6468,NA,NA,p.Leu162Arg,-1.16,-1.21,2,L492R +urn:mavedb:00000044-a-1#6469,NA,NA,p.Leu162Ser,-3.35,-3.32,1,L492S +urn:mavedb:00000044-a-1#6470,NA,NA,p.Leu162Ser,-3.29,-3.32,2,L492S +urn:mavedb:00000044-a-1#6471,NA,NA,p.Leu162Thr,-0.76,-0.78,1,L492T +urn:mavedb:00000044-a-1#6472,NA,NA,p.Leu162Thr,-0.79,-0.78,2,L492T +urn:mavedb:00000044-a-1#6473,NA,NA,p.Leu162Val,-0.14,-0.17,1,L492V +urn:mavedb:00000044-a-1#6474,NA,NA,p.Leu162Val,-0.2,-0.17,2,L492V +urn:mavedb:00000044-a-1#6475,NA,NA,p.Leu162Trp,-1.84,-1.9,1,L492W +urn:mavedb:00000044-a-1#6476,NA,NA,p.Leu162Trp,-1.96,-1.9,2,L492W +urn:mavedb:00000044-a-1#6477,NA,NA,p.Leu162Tyr,-1,-1.16,1,L492Y +urn:mavedb:00000044-a-1#6478,NA,NA,p.Leu162Tyr,-1.32,-1.16,2,L492Y +urn:mavedb:00000044-a-1#6479,NA,NA,p.Leu162*,NA,NA,1,L492 +urn:mavedb:00000044-a-1#6480,NA,NA,p.Leu162*,NA,NA,2,L492 +urn:mavedb:00000044-a-1#6481,NA,NA,p.Gln163Ala,0,0.13,1,Q493A +urn:mavedb:00000044-a-1#6482,NA,NA,p.Gln163Ala,0.26,0.13,2,Q493A +urn:mavedb:00000044-a-1#6483,NA,NA,p.Gln163Cys,-0.03,-0.03,1,Q493C +urn:mavedb:00000044-a-1#6484,NA,NA,p.Gln163Cys,-0.02,-0.03,2,Q493C +urn:mavedb:00000044-a-1#6485,NA,NA,p.Gln163Asp,-1.5,-1.57,1,Q493D +urn:mavedb:00000044-a-1#6486,NA,NA,p.Gln163Asp,-1.63,-1.57,2,Q493D +urn:mavedb:00000044-a-1#6487,NA,NA,p.Gln163Glu,-0.56,-0.56,1,Q493E +urn:mavedb:00000044-a-1#6488,NA,NA,p.Gln163Glu,-0.57,-0.56,2,Q493E +urn:mavedb:00000044-a-1#6489,NA,NA,p.Gln163Phe,0,0.06,1,Q493F +urn:mavedb:00000044-a-1#6490,NA,NA,p.Gln163Phe,0.13,0.06,2,Q493F +urn:mavedb:00000044-a-1#6491,NA,NA,p.Gln163Gly,-0.06,0.01,1,Q493G +urn:mavedb:00000044-a-1#6492,NA,NA,p.Gln163Gly,0.07,0.01,2,Q493G +urn:mavedb:00000044-a-1#6493,NA,NA,p.Gln163His,0,-0.01,1,Q493H +urn:mavedb:00000044-a-1#6494,NA,NA,p.Gln163His,-0.02,-0.01,2,Q493H +urn:mavedb:00000044-a-1#6495,NA,NA,p.Gln163Ile,-0.09,-0.08,1,Q493I +urn:mavedb:00000044-a-1#6496,NA,NA,p.Gln163Ile,-0.07,-0.08,2,Q493I +urn:mavedb:00000044-a-1#6497,NA,NA,p.Gln163Lys,0.03,0.05,1,Q493K +urn:mavedb:00000044-a-1#6498,NA,NA,p.Gln163Lys,0.07,0.05,2,Q493K +urn:mavedb:00000044-a-1#6499,NA,NA,p.Gln163Leu,0.06,0.05,1,Q493L +urn:mavedb:00000044-a-1#6500,NA,NA,p.Gln163Leu,0.05,0.05,2,Q493L +urn:mavedb:00000044-a-1#6501,NA,NA,p.Gln163Met,0,0.18,1,Q493M +urn:mavedb:00000044-a-1#6502,NA,NA,p.Gln163Met,0.35,0.18,2,Q493M +urn:mavedb:00000044-a-1#6503,NA,NA,p.Gln163Asn,-0.21,-0.21,1,Q493N +urn:mavedb:00000044-a-1#6504,NA,NA,p.Gln163Asn,-0.21,-0.21,2,Q493N +urn:mavedb:00000044-a-1#6505,NA,NA,p.Gln163Pro,-0.76,-0.72,1,Q493P +urn:mavedb:00000044-a-1#6506,NA,NA,p.Gln163Pro,-0.68,-0.72,2,Q493P +urn:mavedb:00000044-a-1#6507,NA,NA,p.Gln163Arg,-0.08,-0.09,1,Q493R +urn:mavedb:00000044-a-1#6508,NA,NA,p.Gln163Arg,-0.11,-0.09,2,Q493R +urn:mavedb:00000044-a-1#6509,NA,NA,p.Gln163Ser,-0.37,-0.18,1,Q493S +urn:mavedb:00000044-a-1#6510,NA,NA,p.Gln163Ser,0,-0.18,2,Q493S +urn:mavedb:00000044-a-1#6511,NA,NA,p.Gln163Thr,-0.15,-0.08,1,Q493T +urn:mavedb:00000044-a-1#6512,NA,NA,p.Gln163Thr,-0.01,-0.08,2,Q493T +urn:mavedb:00000044-a-1#6513,NA,NA,p.Gln163Val,0.08,0.05,1,Q493V +urn:mavedb:00000044-a-1#6514,NA,NA,p.Gln163Val,0.01,0.05,2,Q493V +urn:mavedb:00000044-a-1#6515,NA,NA,p.Gln163Trp,-0.09,-0.14,1,Q493W +urn:mavedb:00000044-a-1#6516,NA,NA,p.Gln163Trp,-0.18,-0.14,2,Q493W +urn:mavedb:00000044-a-1#6517,NA,NA,p.Gln163Tyr,0.01,0.12,1,Q493Y +urn:mavedb:00000044-a-1#6518,NA,NA,p.Gln163Tyr,0.22,0.12,2,Q493Y +urn:mavedb:00000044-a-1#6519,NA,NA,p.Gln163*,NA,NA,1,Q493 +urn:mavedb:00000044-a-1#6520,NA,NA,p.Gln163*,NA,NA,2,Q493 +urn:mavedb:00000044-a-1#6521,NA,NA,p.Ser164Ala,0.06,0.03,1,S494A +urn:mavedb:00000044-a-1#6522,NA,NA,p.Ser164Ala,0,0.03,2,S494A +urn:mavedb:00000044-a-1#6523,NA,NA,p.Ser164Cys,-0.11,-0.11,1,S494C +urn:mavedb:00000044-a-1#6524,NA,NA,p.Ser164Cys,-0.1,-0.11,2,S494C +urn:mavedb:00000044-a-1#6525,NA,NA,p.Ser164Asp,-0.96,-1.1,1,S494D +urn:mavedb:00000044-a-1#6526,NA,NA,p.Ser164Asp,-1.23,-1.1,2,S494D +urn:mavedb:00000044-a-1#6527,NA,NA,p.Ser164Glu,-0.2,-0.07,1,S494E +urn:mavedb:00000044-a-1#6528,NA,NA,p.Ser164Glu,0.06,-0.07,2,S494E +urn:mavedb:00000044-a-1#6529,NA,NA,p.Ser164Phe,-0.13,-0.19,1,S494F +urn:mavedb:00000044-a-1#6530,NA,NA,p.Ser164Phe,-0.26,-0.19,2,S494F +urn:mavedb:00000044-a-1#6531,NA,NA,p.Ser164Gly,-0.29,-0.34,1,S494G +urn:mavedb:00000044-a-1#6533,NA,NA,p.Ser164His,0.03,0.06,1,S494H +urn:mavedb:00000044-a-1#6534,NA,NA,p.Ser164His,0.09,0.06,2,S494H +urn:mavedb:00000044-a-1#6535,NA,NA,p.Ser164Ile,-0.52,-0.64,1,S494I +urn:mavedb:00000044-a-1#6536,NA,NA,p.Ser164Ile,-0.77,-0.64,2,S494I +urn:mavedb:00000044-a-1#6537,NA,NA,p.Ser164Lys,0.1,0.05,1,S494K +urn:mavedb:00000044-a-1#6574,NA,NA,p.Tyr165His,-1.24,-1.1,2,Y495H +urn:mavedb:00000044-a-1#6538,NA,NA,p.Ser164Lys,0.01,0.05,2,S494K +urn:mavedb:00000044-a-1#6539,NA,NA,p.Ser164Leu,-0.27,-0.35,1,S494L +urn:mavedb:00000044-a-1#6540,NA,NA,p.Ser164Leu,-0.43,-0.35,2,S494L +urn:mavedb:00000044-a-1#6541,NA,NA,p.Ser164Met,0,-0.03,1,S494M +urn:mavedb:00000044-a-1#6542,NA,NA,p.Ser164Met,-0.06,-0.03,2,S494M +urn:mavedb:00000044-a-1#6543,NA,NA,p.Ser164Asn,0.01,-0.02,1,S494N +urn:mavedb:00000044-a-1#6544,NA,NA,p.Ser164Asn,-0.05,-0.02,2,S494N +urn:mavedb:00000044-a-1#6545,NA,NA,p.Ser164Pro,-0.05,0,1,S494P +urn:mavedb:00000044-a-1#6546,NA,NA,p.Ser164Pro,0.06,0,2,S494P +urn:mavedb:00000044-a-1#6547,NA,NA,p.Ser164Gln,-0.01,-0.01,1,S494Q +urn:mavedb:00000044-a-1#6548,NA,NA,p.Ser164Gln,-0.01,-0.01,2,S494Q +urn:mavedb:00000044-a-1#6549,NA,NA,p.Ser164Arg,-0.02,0.05,1,S494R +urn:mavedb:00000044-a-1#6550,NA,NA,p.Ser164Arg,0.12,0.05,2,S494R +urn:mavedb:00000044-a-1#6551,NA,NA,p.Ser164Thr,-0.08,-0.01,1,S494T +urn:mavedb:00000044-a-1#6552,NA,NA,p.Ser164Thr,0.06,-0.01,2,S494T +urn:mavedb:00000044-a-1#6553,NA,NA,p.Ser164Val,-0.23,-0.21,1,S494V +urn:mavedb:00000044-a-1#6554,NA,NA,p.Ser164Val,-0.19,-0.21,2,S494V +urn:mavedb:00000044-a-1#6555,NA,NA,p.Ser164Trp,-0.25,-0.25,1,S494W +urn:mavedb:00000044-a-1#6556,NA,NA,p.Ser164Trp,-0.25,-0.25,2,S494W +urn:mavedb:00000044-a-1#6557,NA,NA,p.Ser164Tyr,-0.12,-0.1,1,S494Y +urn:mavedb:00000044-a-1#6558,NA,NA,p.Ser164Tyr,-0.08,-0.1,2,S494Y +urn:mavedb:00000044-a-1#6559,NA,NA,p.Ser164*,NA,NA,1,S494 +urn:mavedb:00000044-a-1#6560,NA,NA,p.Ser164*,NA,NA,2,S494 +urn:mavedb:00000044-a-1#6561,NA,NA,p.Tyr165Ala,-2.26,-2.35,1,Y495A +urn:mavedb:00000044-a-1#6562,NA,NA,p.Tyr165Ala,-2.45,-2.35,2,Y495A +urn:mavedb:00000044-a-1#6563,NA,NA,p.Tyr165Cys,-2.22,-2.33,1,Y495C +urn:mavedb:00000044-a-1#6564,NA,NA,p.Tyr165Cys,-2.44,-2.33,2,Y495C +urn:mavedb:00000044-a-1#6565,NA,NA,p.Tyr165Asp,-2.69,-2.61,1,Y495D +urn:mavedb:00000044-a-1#6566,NA,NA,p.Tyr165Asp,-2.52,-2.61,2,Y495D +urn:mavedb:00000044-a-1#6567,NA,NA,p.Tyr165Glu,-2.55,-2.6,1,Y495E +urn:mavedb:00000044-a-1#6568,NA,NA,p.Tyr165Glu,-2.66,-2.6,2,Y495E +urn:mavedb:00000044-a-1#6569,NA,NA,p.Tyr165Phe,-0.51,-0.5,1,Y495F +urn:mavedb:00000044-a-1#6570,NA,NA,p.Tyr165Phe,-0.48,-0.5,2,Y495F +urn:mavedb:00000044-a-1#6571,NA,NA,p.Tyr165Gly,-3.87,-3.93,1,Y495G +urn:mavedb:00000044-a-1#6572,NA,NA,p.Tyr165Gly,-3.98,-3.93,2,Y495G +urn:mavedb:00000044-a-1#6573,NA,NA,p.Tyr165His,-0.97,-1.1,1,Y495H +urn:mavedb:00000044-a-1#6575,NA,NA,p.Tyr165Ile,-1.4,-1.54,1,Y495I +urn:mavedb:00000044-a-1#6576,NA,NA,p.Tyr165Ile,-1.67,-1.54,2,Y495I +urn:mavedb:00000044-a-1#6577,NA,NA,p.Tyr165Lys,-2.19,-2.14,1,Y495K +urn:mavedb:00000044-a-1#6578,NA,NA,p.Tyr165Lys,-2.1,-2.14,2,Y495K +urn:mavedb:00000044-a-1#6579,NA,NA,p.Tyr165Leu,-1.62,-1.65,1,Y495L +urn:mavedb:00000044-a-1#6580,NA,NA,p.Tyr165Leu,-1.68,-1.65,2,Y495L +urn:mavedb:00000044-a-1#6581,NA,NA,p.Tyr165Met,-0.76,-0.87,1,Y495M +urn:mavedb:00000044-a-1#6582,NA,NA,p.Tyr165Met,-0.97,-0.87,2,Y495M +urn:mavedb:00000044-a-1#6583,NA,NA,p.Tyr165Asn,-1.36,-1.43,1,Y495N +urn:mavedb:00000044-a-1#6584,NA,NA,p.Tyr165Asn,-1.5,-1.43,2,Y495N +urn:mavedb:00000044-a-1#6585,NA,NA,p.Tyr165Pro,-2.79,-2.67,1,Y495P +urn:mavedb:00000044-a-1#6586,NA,NA,p.Tyr165Pro,-2.54,-2.67,2,Y495P +urn:mavedb:00000044-a-1#6587,NA,NA,p.Tyr165Gln,-1.98,-1.98,1,Y495Q +urn:mavedb:00000044-a-1#6588,NA,NA,p.Tyr165Gln,-1.97,-1.98,2,Y495Q +urn:mavedb:00000044-a-1#6589,NA,NA,p.Tyr165Arg,-1.45,-1.59,1,Y495R +urn:mavedb:00000044-a-1#6590,NA,NA,p.Tyr165Arg,-1.73,-1.59,2,Y495R +urn:mavedb:00000044-a-1#6591,NA,NA,p.Tyr165Ser,-2.35,-2.43,1,Y495S +urn:mavedb:00000044-a-1#6592,NA,NA,p.Tyr165Ser,-2.52,-2.43,2,Y495S +urn:mavedb:00000044-a-1#6593,NA,NA,p.Tyr165Thr,-2.05,-2.14,1,Y495T +urn:mavedb:00000044-a-1#6594,NA,NA,p.Tyr165Thr,-2.24,-2.14,2,Y495T +urn:mavedb:00000044-a-1#6595,NA,NA,p.Tyr165Val,-1.82,-1.91,1,Y495V +urn:mavedb:00000044-a-1#6596,NA,NA,p.Tyr165Val,-2,-1.91,2,Y495V +urn:mavedb:00000044-a-1#6597,NA,NA,p.Tyr165Trp,-0.81,-0.82,1,Y495W +urn:mavedb:00000044-a-1#6598,NA,NA,p.Tyr165Trp,-0.84,-0.82,2,Y495W +urn:mavedb:00000044-a-1#6599,NA,NA,p.Tyr165*,NA,NA,1,Y495 +urn:mavedb:00000044-a-1#6600,NA,NA,p.Tyr165*,NA,NA,2,Y495 +urn:mavedb:00000044-a-1#6601,NA,NA,p.Gly166Ala,-0.44,-0.53,1,G496A +urn:mavedb:00000044-a-1#6602,NA,NA,p.Gly166Ala,-0.61,-0.53,2,G496A +urn:mavedb:00000044-a-1#6603,NA,NA,p.Gly166Cys,-1.4,-1.42,1,G496C +urn:mavedb:00000044-a-1#6604,NA,NA,p.Gly166Cys,-1.44,-1.42,2,G496C +urn:mavedb:00000044-a-1#6605,NA,NA,p.Gly166Asp,-2.17,-2.21,1,G496D +urn:mavedb:00000044-a-1#6606,NA,NA,p.Gly166Asp,-2.26,-2.21,2,G496D +urn:mavedb:00000044-a-1#6607,NA,NA,p.Gly166Glu,-2.32,-2.33,1,G496E +urn:mavedb:00000044-a-1#6608,NA,NA,p.Gly166Glu,-2.34,-2.33,2,G496E +urn:mavedb:00000044-a-1#6609,NA,NA,p.Gly166Phe,-2.06,-2.12,1,G496F +urn:mavedb:00000044-a-1#6610,NA,NA,p.Gly166Phe,-2.17,-2.12,2,G496F +urn:mavedb:00000044-a-1#6611,NA,NA,p.Gly166His,-1.48,-1.52,1,G496H +urn:mavedb:00000044-a-1#4691,NA,NA,p.Asn118Gly,-0.81,-0.91,1,N448G +urn:mavedb:00000044-a-1#5679,NA,NA,p.Ile142*,NA,NA,1,I472 +urn:mavedb:00000044-a-1#5799,NA,NA,p.Ala145*,NA,NA,1,A475 +urn:mavedb:00000044-a-1#54,NA,NA,p.Ile2His,0.09,0.04,2,I332H +urn:mavedb:00000044-a-1#55,NA,NA,p.Ile2Lys,-0.08,-0.05,1,I332K +urn:mavedb:00000044-a-1#56,NA,NA,p.Ile2Lys,-0.03,-0.05,2,I332K +urn:mavedb:00000044-a-1#57,NA,NA,p.Ile2Leu,0.02,0,1,I332L +urn:mavedb:00000044-a-1#58,NA,NA,p.Ile2Leu,-0.02,0,2,I332L +urn:mavedb:00000044-a-1#59,NA,NA,p.Ile2Met,-0.01,0,1,I332M +urn:mavedb:00000044-a-1#60,NA,NA,p.Ile2Met,0,0,2,I332M +urn:mavedb:00000044-a-1#61,NA,NA,p.Ile2Asn,-0.01,0,1,I332N +urn:mavedb:00000044-a-1#62,NA,NA,p.Ile2Asn,0.01,0,2,I332N +urn:mavedb:00000044-a-1#63,NA,NA,p.Ile2Pro,0.01,0.06,1,I332P +urn:mavedb:00000044-a-1#64,NA,NA,p.Ile2Pro,0.11,0.06,2,I332P +urn:mavedb:00000044-a-1#65,NA,NA,p.Ile2Gln,-0.02,-0.02,1,I332Q +urn:mavedb:00000044-a-1#66,NA,NA,p.Ile2Gln,-0.02,-0.02,2,I332Q +urn:mavedb:00000044-a-1#67,NA,NA,p.Ile2Arg,-0.02,0,1,I332R +urn:mavedb:00000044-a-1#68,NA,NA,p.Ile2Arg,0.02,0,2,I332R +urn:mavedb:00000044-a-1#69,NA,NA,p.Ile2Ser,-0.01,-0.04,1,I332S +urn:mavedb:00000044-a-1#70,NA,NA,p.Ile2Ser,-0.07,-0.04,2,I332S +urn:mavedb:00000044-a-1#71,NA,NA,p.Ile2Thr,-0.01,-0.03,1,I332T +urn:mavedb:00000044-a-1#72,NA,NA,p.Ile2Thr,-0.05,-0.03,2,I332T +urn:mavedb:00000044-a-1#73,NA,NA,p.Ile2Val,0.02,0,1,I332V +urn:mavedb:00000044-a-1#74,NA,NA,p.Ile2Val,-0.03,0,2,I332V +urn:mavedb:00000044-a-1#75,NA,NA,p.Ile2Trp,-0.03,-0.03,1,I332W +urn:mavedb:00000044-a-1#76,NA,NA,p.Ile2Trp,-0.03,-0.03,2,I332W +urn:mavedb:00000044-a-1#77,NA,NA,p.Ile2Tyr,-0.02,-0.03,1,I332Y +urn:mavedb:00000044-a-1#78,NA,NA,p.Ile2Tyr,-0.04,-0.03,2,I332Y +urn:mavedb:00000044-a-1#79,NA,NA,p.Ile2*,NA,NA,1,I332 +urn:mavedb:00000044-a-1#80,NA,NA,p.Ile2*,NA,NA,2,I332 +urn:mavedb:00000044-a-1#81,NA,NA,p.Thr3Ala,-0.04,-0.01,1,T333A +urn:mavedb:00000044-a-1#82,NA,NA,p.Thr3Ala,0.01,-0.01,2,T333A +urn:mavedb:00000044-a-1#83,NA,NA,p.Thr3Cys,-0.12,-0.14,1,T333C +urn:mavedb:00000044-a-1#84,NA,NA,p.Thr3Cys,-0.17,-0.14,2,T333C +urn:mavedb:00000044-a-1#85,NA,NA,p.Thr3Asp,0.02,-0.01,1,T333D +urn:mavedb:00000044-a-1#86,NA,NA,p.Thr3Asp,-0.04,-0.01,2,T333D +urn:mavedb:00000044-a-1#87,NA,NA,p.Thr3Glu,-0.21,-0.15,1,T333E +urn:mavedb:00000044-a-1#88,NA,NA,p.Thr3Glu,-0.09,-0.15,2,T333E +urn:mavedb:00000044-a-1#89,NA,NA,p.Thr3Phe,-0.09,-0.15,1,T333F +urn:mavedb:00000044-a-1#90,NA,NA,p.Thr3Phe,-0.22,-0.15,2,T333F +urn:mavedb:00000044-a-1#91,NA,NA,p.Thr3Gly,-0.05,-0.07,1,T333G +urn:mavedb:00000044-a-1#92,NA,NA,p.Thr3Gly,-0.08,-0.07,2,T333G +urn:mavedb:00000044-a-1#93,NA,NA,p.Thr3His,-0.12,-0.07,1,T333H +urn:mavedb:00000044-a-1#94,NA,NA,p.Thr3His,-0.02,-0.07,2,T333H +urn:mavedb:00000044-a-1#95,NA,NA,p.Thr3Ile,-0.07,-0.06,1,T333I +urn:mavedb:00000044-a-1#96,NA,NA,p.Thr3Ile,-0.04,-0.06,2,T333I +urn:mavedb:00000044-a-1#97,NA,NA,p.Thr3Lys,0.01,-0.01,1,T333K +urn:mavedb:00000044-a-1#98,NA,NA,p.Thr3Lys,-0.02,-0.01,2,T333K +urn:mavedb:00000044-a-1#99,NA,NA,p.Thr3Leu,0.04,-0.01,1,T333L +urn:mavedb:00000044-a-1#1,NA,NA,p.Asn1Ala,-0.05,-0.03,1,N331A +urn:mavedb:00000044-a-1#2,NA,NA,p.Asn1Ala,-0.02,-0.03,2,N331A +urn:mavedb:00000044-a-1#3,NA,NA,p.Asn1Cys,-0.08,-0.09,1,N331C +urn:mavedb:00000044-a-1#4,NA,NA,p.Asn1Cys,-0.1,-0.09,2,N331C +urn:mavedb:00000044-a-1#5,NA,NA,p.Asn1Asp,0,0.03,1,N331D +urn:mavedb:00000044-a-1#6,NA,NA,p.Asn1Asp,0.07,0.03,2,N331D +urn:mavedb:00000044-a-1#7,NA,NA,p.Asn1Glu,0.02,0,1,N331E +urn:mavedb:00000044-a-1#8,NA,NA,p.Asn1Glu,-0.02,0,2,N331E +urn:mavedb:00000044-a-1#9,NA,NA,p.Asn1Phe,-0.03,-0.1,1,N331F +urn:mavedb:00000044-a-1#10,NA,NA,p.Asn1Phe,-0.16,-0.1,2,N331F +urn:mavedb:00000044-a-1#11,NA,NA,p.Asn1Gly,-0.06,-0.04,1,N331G +urn:mavedb:00000044-a-1#12,NA,NA,p.Asn1Gly,-0.02,-0.04,2,N331G +urn:mavedb:00000044-a-1#13,NA,NA,p.Asn1His,0.01,-0.02,1,N331H +urn:mavedb:00000044-a-1#14,NA,NA,p.Asn1His,-0.05,-0.02,2,N331H +urn:mavedb:00000044-a-1#15,NA,NA,p.Asn1Ile,-0.06,-0.07,1,N331I +urn:mavedb:00000044-a-1#16,NA,NA,p.Asn1Ile,-0.08,-0.07,2,N331I +urn:mavedb:00000044-a-1#17,NA,NA,p.Asn1Lys,-0.01,-0.01,1,N331K +urn:mavedb:00000044-a-1#18,NA,NA,p.Asn1Lys,-0.01,-0.01,2,N331K +urn:mavedb:00000044-a-1#19,NA,NA,p.Asn1Leu,-0.08,-0.05,1,N331L +urn:mavedb:00000044-a-1#20,NA,NA,p.Asn1Leu,-0.01,-0.05,2,N331L +urn:mavedb:00000044-a-1#21,NA,NA,p.Asn1Met,-0.01,-0.02,1,N331M +urn:mavedb:00000044-a-1#22,NA,NA,p.Asn1Met,-0.03,-0.02,2,N331M +urn:mavedb:00000044-a-1#23,NA,NA,p.Asn1Pro,-0.12,-0.03,1,N331P +urn:mavedb:00000044-a-1#24,NA,NA,p.Asn1Pro,0.05,-0.03,2,N331P +urn:mavedb:00000044-a-1#25,NA,NA,p.Asn1Gln,0.01,0.01,1,N331Q +urn:mavedb:00000044-a-1#26,NA,NA,p.Asn1Gln,0,0.01,2,N331Q +urn:mavedb:00000044-a-1#27,NA,NA,p.Asn1Arg,-0.02,-0.02,1,N331R +urn:mavedb:00000044-a-1#28,NA,NA,p.Asn1Arg,-0.02,-0.02,2,N331R +urn:mavedb:00000044-a-1#29,NA,NA,p.Asn1Ser,-0.05,-0.03,1,N331S +urn:mavedb:00000044-a-1#30,NA,NA,p.Asn1Ser,0,-0.03,2,N331S +urn:mavedb:00000044-a-1#31,NA,NA,p.Asn1Thr,0.06,0.06,1,N331T +urn:mavedb:00000044-a-1#32,NA,NA,p.Asn1Thr,0.06,0.06,2,N331T +urn:mavedb:00000044-a-1#33,NA,NA,p.Asn1Val,-0.04,-0.04,1,N331V +urn:mavedb:00000044-a-1#34,NA,NA,p.Asn1Val,-0.04,-0.04,2,N331V +urn:mavedb:00000044-a-1#35,NA,NA,p.Asn1Trp,-0.14,-0.16,1,N331W +urn:mavedb:00000044-a-1#36,NA,NA,p.Asn1Trp,-0.18,-0.16,2,N331W +urn:mavedb:00000044-a-1#37,NA,NA,p.Asn1Tyr,-0.02,-0.06,1,N331Y +urn:mavedb:00000044-a-1#38,NA,NA,p.Asn1Tyr,-0.1,-0.06,2,N331Y +urn:mavedb:00000044-a-1#39,NA,NA,p.Asn1*,NA,NA,1,N331 +urn:mavedb:00000044-a-1#40,NA,NA,p.Asn1*,NA,NA,2,N331 +urn:mavedb:00000044-a-1#41,NA,NA,p.Ile2Ala,0.02,0,1,I332A +urn:mavedb:00000044-a-1#42,NA,NA,p.Ile2Ala,-0.02,0,2,I332A +urn:mavedb:00000044-a-1#43,NA,NA,p.Ile2Cys,-0.02,-0.09,1,I332C +urn:mavedb:00000044-a-1#44,NA,NA,p.Ile2Cys,-0.15,-0.09,2,I332C +urn:mavedb:00000044-a-1#45,NA,NA,p.Ile2Asp,-0.01,-0.02,1,I332D +urn:mavedb:00000044-a-1#46,NA,NA,p.Ile2Asp,-0.02,-0.02,2,I332D +urn:mavedb:00000044-a-1#47,NA,NA,p.Ile2Glu,0.06,0.08,1,I332E +urn:mavedb:00000044-a-1#48,NA,NA,p.Ile2Glu,0.1,0.08,2,I332E +urn:mavedb:00000044-a-1#49,NA,NA,p.Ile2Phe,-0.33,-0.22,1,I332F +urn:mavedb:00000044-a-1#50,NA,NA,p.Ile2Phe,-0.11,-0.22,2,I332F +urn:mavedb:00000044-a-1#51,NA,NA,p.Ile2Gly,-0.15,-0.08,1,I332G +urn:mavedb:00000044-a-1#52,NA,NA,p.Ile2Gly,-0.02,-0.08,2,I332G +urn:mavedb:00000044-a-1#53,NA,NA,p.Ile2His,0,0.04,1,I332H +urn:mavedb:00000044-a-1#105,NA,NA,p.Thr3Pro,0.05,0.03,1,T333P +urn:mavedb:00000044-a-1#106,NA,NA,p.Thr3Pro,0.02,0.03,2,T333P +urn:mavedb:00000044-a-1#107,NA,NA,p.Thr3Gln,0,0.02,1,T333Q +urn:mavedb:00000044-a-1#108,NA,NA,p.Thr3Gln,0.04,0.02,2,T333Q +urn:mavedb:00000044-a-1#109,NA,NA,p.Thr3Arg,0.04,0,1,T333R +urn:mavedb:00000044-a-1#110,NA,NA,p.Thr3Arg,-0.04,0,2,T333R +urn:mavedb:00000044-a-1#111,NA,NA,p.Thr3Ser,0,-0.08,1,T333S +urn:mavedb:00000044-a-1#112,NA,NA,p.Thr3Ser,-0.16,-0.08,2,T333S +urn:mavedb:00000044-a-1#113,NA,NA,p.Thr3Val,-0.06,-0.05,1,T333V +urn:mavedb:00000044-a-1#114,NA,NA,p.Thr3Val,-0.03,-0.05,2,T333V +urn:mavedb:00000044-a-1#115,NA,NA,p.Thr3Trp,-0.24,-0.21,1,T333W +urn:mavedb:00000044-a-1#116,NA,NA,p.Thr3Trp,-0.19,-0.21,2,T333W +urn:mavedb:00000044-a-1#117,NA,NA,p.Thr3Tyr,-0.05,-0.07,1,T333Y +urn:mavedb:00000044-a-1#118,NA,NA,p.Thr3Tyr,-0.08,-0.07,2,T333Y +urn:mavedb:00000044-a-1#119,NA,NA,p.Thr3*,NA,NA,1,T333 +urn:mavedb:00000044-a-1#120,NA,NA,p.Thr3*,NA,NA,2,T333 +urn:mavedb:00000044-a-1#121,NA,NA,p.Asn4Ala,-0.01,-0.03,1,N334A +urn:mavedb:00000044-a-1#122,NA,NA,p.Asn4Ala,-0.05,-0.03,2,N334A +urn:mavedb:00000044-a-1#123,NA,NA,p.Asn4Cys,-0.11,-0.11,1,N334C +urn:mavedb:00000044-a-1#124,NA,NA,p.Asn4Cys,-0.12,-0.11,2,N334C +urn:mavedb:00000044-a-1#125,NA,NA,p.Asn4Asp,0.18,0.07,1,N334D +urn:mavedb:00000044-a-1#126,NA,NA,p.Asn4Asp,-0.05,0.07,2,N334D +urn:mavedb:00000044-a-1#127,NA,NA,p.Asn4Glu,0.01,0.01,1,N334E +urn:mavedb:00000044-a-1#128,NA,NA,p.Asn4Glu,0.01,0.01,2,N334E +urn:mavedb:00000044-a-1#129,NA,NA,p.Asn4Phe,-0.25,-0.22,1,N334F +urn:mavedb:00000044-a-1#130,NA,NA,p.Asn4Phe,-0.2,-0.22,2,N334F +urn:mavedb:00000044-a-1#131,NA,NA,p.Asn4Gly,-0.03,-0.03,1,N334G +urn:mavedb:00000044-a-1#100,NA,NA,p.Thr3Leu,-0.06,-0.01,2,T333L +urn:mavedb:00000044-a-1#101,NA,NA,p.Thr3Met,-0.04,-0.02,1,T333M +urn:mavedb:00000044-a-1#102,NA,NA,p.Thr3Met,-0.01,-0.02,2,T333M +urn:mavedb:00000044-a-1#103,NA,NA,p.Thr3Asn,-0.08,-0.06,1,T333N +urn:mavedb:00000044-a-1#104,NA,NA,p.Thr3Asn,-0.04,-0.06,2,T333N +urn:mavedb:00000044-a-1#194,NA,NA,p.Leu5Val,-0.01,-0.08,2,L335V +urn:mavedb:00000044-a-1#195,NA,NA,p.Leu5Trp,-0.02,-0.05,1,L335W +urn:mavedb:00000044-a-1#196,NA,NA,p.Leu5Trp,-0.07,-0.05,2,L335W +urn:mavedb:00000044-a-1#197,NA,NA,p.Leu5Tyr,0,-0.02,1,L335Y +urn:mavedb:00000044-a-1#198,NA,NA,p.Leu5Tyr,-0.04,-0.02,2,L335Y +urn:mavedb:00000044-a-1#199,NA,NA,p.Leu5*,NA,NA,1,L335 +urn:mavedb:00000044-a-1#200,NA,NA,p.Leu5*,NA,NA,2,L335 +urn:mavedb:00000044-a-1#201,NA,NA,p.Cys6Ala,-0.69,-0.69,1,C336A +urn:mavedb:00000044-a-1#202,NA,NA,p.Cys6Ala,-0.69,-0.69,2,C336A +urn:mavedb:00000044-a-1#203,NA,NA,p.Cys6Asp,-0.46,-0.48,1,C336D +urn:mavedb:00000044-a-1#204,NA,NA,p.Cys6Asp,-0.49,-0.48,2,C336D +urn:mavedb:00000044-a-1#205,NA,NA,p.Cys6Glu,-0.58,-0.61,1,C336E +urn:mavedb:00000044-a-1#206,NA,NA,p.Cys6Glu,-0.64,-0.61,2,C336E +urn:mavedb:00000044-a-1#207,NA,NA,p.Cys6Phe,-0.52,-0.57,1,C336F +urn:mavedb:00000044-a-1#208,NA,NA,p.Cys6Phe,-0.62,-0.57,2,C336F +urn:mavedb:00000044-a-1#209,NA,NA,p.Cys6Gly,-0.62,-0.65,1,C336G +urn:mavedb:00000044-a-1#210,NA,NA,p.Cys6Gly,-0.68,-0.65,2,C336G +urn:mavedb:00000044-a-1#211,NA,NA,p.Cys6His,-0.68,-0.71,1,C336H +urn:mavedb:00000044-a-1#212,NA,NA,p.Cys6His,-0.74,-0.71,2,C336H +urn:mavedb:00000044-a-1#213,NA,NA,p.Cys6Ile,-0.71,-0.75,1,C336I +urn:mavedb:00000044-a-1#214,NA,NA,p.Cys6Ile,-0.79,-0.75,2,C336I +urn:mavedb:00000044-a-1#215,NA,NA,p.Cys6Lys,-0.84,-0.93,1,C336K +urn:mavedb:00000044-a-1#216,NA,NA,p.Cys6Lys,-1.03,-0.93,2,C336K +urn:mavedb:00000044-a-1#217,NA,NA,p.Cys6Leu,-0.81,-0.81,1,C336L +urn:mavedb:00000044-a-1#218,NA,NA,p.Cys6Leu,-0.81,-0.81,2,C336L +urn:mavedb:00000044-a-1#219,NA,NA,p.Cys6Met,-0.73,-0.75,1,C336M +urn:mavedb:00000044-a-1#132,NA,NA,p.Asn4Gly,-0.02,-0.03,2,N334G +urn:mavedb:00000044-a-1#133,NA,NA,p.Asn4His,0.04,-0.02,1,N334H +urn:mavedb:00000044-a-1#134,NA,NA,p.Asn4His,-0.07,-0.02,2,N334H +urn:mavedb:00000044-a-1#135,NA,NA,p.Asn4Ile,-0.19,-0.2,1,N334I +urn:mavedb:00000044-a-1#136,NA,NA,p.Asn4Ile,-0.2,-0.2,2,N334I +urn:mavedb:00000044-a-1#137,NA,NA,p.Asn4Lys,0,-0.03,1,N334K +urn:mavedb:00000044-a-1#138,NA,NA,p.Asn4Lys,-0.05,-0.03,2,N334K +urn:mavedb:00000044-a-1#139,NA,NA,p.Asn4Leu,-0.2,-0.2,1,N334L +urn:mavedb:00000044-a-1#140,NA,NA,p.Asn4Leu,-0.2,-0.2,2,N334L +urn:mavedb:00000044-a-1#141,NA,NA,p.Asn4Met,-0.03,-0.05,1,N334M +urn:mavedb:00000044-a-1#142,NA,NA,p.Asn4Met,-0.07,-0.05,2,N334M +urn:mavedb:00000044-a-1#143,NA,NA,p.Asn4Pro,-0.21,-0.18,1,N334P +urn:mavedb:00000044-a-1#144,NA,NA,p.Asn4Pro,-0.15,-0.18,2,N334P +urn:mavedb:00000044-a-1#145,NA,NA,p.Asn4Gln,0,0.01,1,N334Q +urn:mavedb:00000044-a-1#146,NA,NA,p.Asn4Gln,0.02,0.01,2,N334Q +urn:mavedb:00000044-a-1#147,NA,NA,p.Asn4Arg,-0.02,0,1,N334R +urn:mavedb:00000044-a-1#148,NA,NA,p.Asn4Arg,0.03,0,2,N334R +urn:mavedb:00000044-a-1#149,NA,NA,p.Asn4Ser,-0.05,-0.06,1,N334S +urn:mavedb:00000044-a-1#150,NA,NA,p.Asn4Ser,-0.08,-0.06,2,N334S +urn:mavedb:00000044-a-1#151,NA,NA,p.Asn4Thr,-0.04,-0.04,1,N334T +urn:mavedb:00000044-a-1#152,NA,NA,p.Asn4Thr,-0.04,-0.04,2,N334T +urn:mavedb:00000044-a-1#153,NA,NA,p.Asn4Val,-0.06,-0.07,1,N334V +urn:mavedb:00000044-a-1#154,NA,NA,p.Asn4Val,-0.08,-0.07,2,N334V +urn:mavedb:00000044-a-1#155,NA,NA,p.Asn4Trp,-0.25,-0.24,1,N334W +urn:mavedb:00000044-a-1#156,NA,NA,p.Asn4Trp,-0.23,-0.24,2,N334W +urn:mavedb:00000044-a-1#157,NA,NA,p.Asn4Tyr,-0.03,-0.09,1,N334Y +urn:mavedb:00000044-a-1#158,NA,NA,p.Asn4Tyr,-0.15,-0.09,2,N334Y +urn:mavedb:00000044-a-1#159,NA,NA,p.Asn4*,NA,NA,1,N334 +urn:mavedb:00000044-a-1#160,NA,NA,p.Asn4*,NA,NA,2,N334 +urn:mavedb:00000044-a-1#161,NA,NA,p.Leu5Ala,0.03,0.04,1,L335A +urn:mavedb:00000044-a-1#181,NA,NA,p.Leu5Asn,0.04,0.03,1,L335N +urn:mavedb:00000044-a-1#182,NA,NA,p.Leu5Asn,0.01,0.03,2,L335N +urn:mavedb:00000044-a-1#183,NA,NA,p.Leu5Pro,0.03,0.06,1,L335P +urn:mavedb:00000044-a-1#184,NA,NA,p.Leu5Pro,0.09,0.06,2,L335P +urn:mavedb:00000044-a-1#185,NA,NA,p.Leu5Gln,-0.03,-0.02,1,L335Q +urn:mavedb:00000044-a-1#186,NA,NA,p.Leu5Gln,0,-0.02,2,L335Q +urn:mavedb:00000044-a-1#187,NA,NA,p.Leu5Arg,-0.02,-0.01,1,L335R +urn:mavedb:00000044-a-1#188,NA,NA,p.Leu5Arg,0,-0.01,2,L335R +urn:mavedb:00000044-a-1#189,NA,NA,p.Leu5Ser,0.02,0.01,1,L335S +urn:mavedb:00000044-a-1#190,NA,NA,p.Leu5Ser,0,0.01,2,L335S +urn:mavedb:00000044-a-1#191,NA,NA,p.Leu5Thr,0.02,0.02,1,L335T +urn:mavedb:00000044-a-1#192,NA,NA,p.Leu5Thr,0.02,0.02,2,L335T +urn:mavedb:00000044-a-1#193,NA,NA,p.Leu5Val,-0.14,-0.08,1,L335V +urn:mavedb:00000044-a-1#222,NA,NA,p.Cys6Asn,-0.53,-0.51,2,C336N +urn:mavedb:00000044-a-1#223,NA,NA,p.Cys6Pro,-0.9,-0.93,1,C336P 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+urn:mavedb:00000044-a-1#387,NA,NA,p.Glu10Arg,-0.27,-0.28,1,E340R +urn:mavedb:00000044-a-1#6612,NA,NA,p.Gly166His,-1.56,-1.52,2,G496H +urn:mavedb:00000044-a-1#6613,NA,NA,p.Gly166Ile,-1.44,-1.51,1,G496I +urn:mavedb:00000044-a-1#6614,NA,NA,p.Gly166Ile,-1.58,-1.51,2,G496I +urn:mavedb:00000044-a-1#6615,NA,NA,p.Gly166Lys,-1.58,-1.65,1,G496K +urn:mavedb:00000044-a-1#6616,NA,NA,p.Gly166Lys,-1.71,-1.65,2,G496K +urn:mavedb:00000044-a-1#6617,NA,NA,p.Gly166Leu,-1.68,-1.7,1,G496L +urn:mavedb:00000044-a-1#6618,NA,NA,p.Gly166Leu,-1.71,-1.7,2,G496L +urn:mavedb:00000044-a-1#6619,NA,NA,p.Gly166Met,-1.56,-1.62,1,G496M +urn:mavedb:00000044-a-1#6620,NA,NA,p.Gly166Met,-1.68,-1.62,2,G496M +urn:mavedb:00000044-a-1#6621,NA,NA,p.Gly166Asn,-0.32,-0.35,1,G496N +urn:mavedb:00000044-a-1#6622,NA,NA,p.Gly166Asn,-0.38,-0.35,2,G496N +urn:mavedb:00000044-a-1#6623,NA,NA,p.Gly166Pro,-1.92,-2.1,1,G496P +urn:mavedb:00000044-a-1#6624,NA,NA,p.Gly166Pro,-2.29,-2.1,2,G496P 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+urn:mavedb:00000044-a-1#467,NA,NA,p.Phe12Arg,-1.34,-1.22,1,F342R +urn:mavedb:00000044-a-1#468,NA,NA,p.Phe12Arg,-1.11,-1.22,2,F342R +urn:mavedb:00000044-a-1#469,NA,NA,p.Phe12Ser,-1.21,-1.34,1,F342S +urn:mavedb:00000044-a-1#470,NA,NA,p.Phe12Ser,-1.47,-1.34,2,F342S +urn:mavedb:00000044-a-1#471,NA,NA,p.Phe12Thr,-0.82,-0.78,1,F342T +urn:mavedb:00000044-a-1#472,NA,NA,p.Phe12Thr,-0.75,-0.78,2,F342T +urn:mavedb:00000044-a-1#473,NA,NA,p.Phe12Val,-0.37,-0.38,1,F342V +urn:mavedb:00000044-a-1#474,NA,NA,p.Phe12Val,-0.38,-0.38,2,F342V +urn:mavedb:00000044-a-1#475,NA,NA,p.Phe12Trp,-0.74,-0.73,1,F342W +urn:mavedb:00000044-a-1#476,NA,NA,p.Phe12Trp,-0.72,-0.73,2,F342W +urn:mavedb:00000044-a-1#492,NA,NA,p.Asn13Gly,-0.23,-0.2,2,N343G +urn:mavedb:00000044-a-1#493,NA,NA,p.Asn13His,-0.26,-0.31,1,N343H +urn:mavedb:00000044-a-1#494,NA,NA,p.Asn13His,-0.36,-0.31,2,N343H +urn:mavedb:00000044-a-1#495,NA,NA,p.Asn13Ile,-0.92,-0.96,1,N343I +urn:mavedb:00000044-a-1#496,NA,NA,p.Asn13Ile,-0.99,-0.96,2,N343I +urn:mavedb:00000044-a-1#497,NA,NA,p.Asn13Lys,-0.34,-0.31,1,N343K +urn:mavedb:00000044-a-1#498,NA,NA,p.Asn13Lys,-0.28,-0.31,2,N343K +urn:mavedb:00000044-a-1#499,NA,NA,p.Asn13Leu,-0.6,-0.58,1,N343L +urn:mavedb:00000044-a-1#500,NA,NA,p.Asn13Leu,-0.57,-0.58,2,N343L +urn:mavedb:00000044-a-1#501,NA,NA,p.Asn13Met,-0.42,-0.49,1,N343M +urn:mavedb:00000044-a-1#502,NA,NA,p.Asn13Met,-0.56,-0.49,2,N343M +urn:mavedb:00000044-a-1#503,NA,NA,p.Asn13Pro,-1.42,-1.47,1,N343P +urn:mavedb:00000044-a-1#504,NA,NA,p.Asn13Pro,-1.52,-1.47,2,N343P +urn:mavedb:00000044-a-1#505,NA,NA,p.Asn13Gln,-0.34,-0.29,1,N343Q +urn:mavedb:00000044-a-1#506,NA,NA,p.Asn13Gln,-0.24,-0.29,2,N343Q +urn:mavedb:00000044-a-1#507,NA,NA,p.Asn13Arg,-0.38,-0.42,1,N343R +urn:mavedb:00000044-a-1#508,NA,NA,p.Asn13Arg,-0.45,-0.42,2,N343R +urn:mavedb:00000044-a-1#518,NA,NA,p.Asn13Tyr,-0.44,-0.46,2,N343Y +urn:mavedb:00000044-a-1#519,NA,NA,p.Asn13*,NA,NA,1,N343 +urn:mavedb:00000044-a-1#520,NA,NA,p.Asn13*,NA,NA,2,N343 +urn:mavedb:00000044-a-1#521,NA,NA,p.Ala14Cys,-0.39,-0.4,1,A344C +urn:mavedb:00000044-a-1#522,NA,NA,p.Ala14Cys,-0.4,-0.4,2,A344C +urn:mavedb:00000044-a-1#523,NA,NA,p.Ala14Asp,-0.36,-0.41,1,A344D +urn:mavedb:00000044-a-1#524,NA,NA,p.Ala14Asp,-0.46,-0.41,2,A344D +urn:mavedb:00000044-a-1#525,NA,NA,p.Ala14Glu,-0.24,-0.26,1,A344E +urn:mavedb:00000044-a-1#526,NA,NA,p.Ala14Glu,-0.28,-0.26,2,A344E +urn:mavedb:00000044-a-1#527,NA,NA,p.Ala14Phe,-0.69,-0.83,1,A344F +urn:mavedb:00000044-a-1#528,NA,NA,p.Ala14Phe,-0.98,-0.83,2,A344F +urn:mavedb:00000044-a-1#639,NA,NA,p.Arg16*,NA,NA,1,R346 +urn:mavedb:00000044-a-1#529,NA,NA,p.Ala14Gly,-0.29,-0.32,1,A344G +urn:mavedb:00000044-a-1#530,NA,NA,p.Ala14Gly,-0.35,-0.32,2,A344G +urn:mavedb:00000044-a-1#531,NA,NA,p.Ala14His,-0.42,-0.46,1,A344H +urn:mavedb:00000044-a-1#532,NA,NA,p.Ala14His,-0.5,-0.46,2,A344H +urn:mavedb:00000044-a-1#533,NA,NA,p.Ala14Ile,-0.46,-0.41,1,A344I +urn:mavedb:00000044-a-1#534,NA,NA,p.Ala14Ile,-0.36,-0.41,2,A344I +urn:mavedb:00000044-a-1#535,NA,NA,p.Ala14Lys,-0.08,-0.1,1,A344K +urn:mavedb:00000044-a-1#536,NA,NA,p.Ala14Lys,-0.13,-0.1,2,A344K +urn:mavedb:00000044-a-1#537,NA,NA,p.Ala14Leu,-0.6,-0.62,1,A344L +urn:mavedb:00000044-a-1#538,NA,NA,p.Ala14Leu,-0.64,-0.62,2,A344L +urn:mavedb:00000044-a-1#539,NA,NA,p.Ala14Met,-0.43,-0.43,1,A344M +urn:mavedb:00000044-a-1#540,NA,NA,p.Ala14Met,-0.43,-0.43,2,A344M +urn:mavedb:00000044-a-1#541,NA,NA,p.Ala14Asn,-0.13,-0.14,1,A344N +urn:mavedb:00000044-a-1#542,NA,NA,p.Ala14Asn,-0.15,-0.14,2,A344N +urn:mavedb:00000044-a-1#543,NA,NA,p.Ala14Pro,-0.64,-0.74,1,A344P +urn:mavedb:00000044-a-1#544,NA,NA,p.Ala14Pro,-0.84,-0.74,2,A344P +urn:mavedb:00000044-a-1#545,NA,NA,p.Ala14Gln,-0.12,-0.1,1,A344Q +urn:mavedb:00000044-a-1#546,NA,NA,p.Ala14Gln,-0.08,-0.1,2,A344Q +urn:mavedb:00000044-a-1#547,NA,NA,p.Ala14Arg,-0.12,-0.17,1,A344R +urn:mavedb:00000044-a-1#548,NA,NA,p.Ala14Arg,-0.23,-0.17,2,A344R +urn:mavedb:00000044-a-1#568,NA,NA,p.Thr15Glu,-0.11,-0.09,2,T345E +urn:mavedb:00000044-a-1#569,NA,NA,p.Thr15Phe,-0.55,-0.58,1,T345F +urn:mavedb:00000044-a-1#570,NA,NA,p.Thr15Phe,-0.61,-0.58,2,T345F +urn:mavedb:00000044-a-1#571,NA,NA,p.Thr15Gly,-0.32,-0.35,1,T345G +urn:mavedb:00000044-a-1#572,NA,NA,p.Thr15Gly,-0.39,-0.35,2,T345G +urn:mavedb:00000044-a-1#573,NA,NA,p.Thr15His,-0.26,-0.26,1,T345H +urn:mavedb:00000044-a-1#574,NA,NA,p.Thr15His,-0.26,-0.26,2,T345H +urn:mavedb:00000044-a-1#575,NA,NA,p.Thr15Ile,-0.43,-0.42,1,T345I +urn:mavedb:00000044-a-1#576,NA,NA,p.Thr15Ile,-0.41,-0.42,2,T345I +urn:mavedb:00000044-a-1#577,NA,NA,p.Thr15Lys,-0.06,-0.07,1,T345K +urn:mavedb:00000044-a-1#578,NA,NA,p.Thr15Lys,-0.07,-0.07,2,T345K +urn:mavedb:00000044-a-1#579,NA,NA,p.Thr15Leu,-0.21,-0.25,1,T345L +urn:mavedb:00000044-a-1#580,NA,NA,p.Thr15Leu,-0.28,-0.25,2,T345L +urn:mavedb:00000044-a-1#581,NA,NA,p.Thr15Met,-0.35,-0.37,1,T345M +urn:mavedb:00000044-a-1#259,NA,NA,p.Pro7Leu,-0.22,-0.27,1,P337L +urn:mavedb:00000044-a-1#260,NA,NA,p.Pro7Leu,-0.31,-0.27,2,P337L +urn:mavedb:00000044-a-1#261,NA,NA,p.Pro7Met,-0.17,-0.19,1,P337M +urn:mavedb:00000044-a-1#262,NA,NA,p.Pro7Met,-0.21,-0.19,2,P337M +urn:mavedb:00000044-a-1#263,NA,NA,p.Pro7Asn,-0.09,-0.03,1,P337N +urn:mavedb:00000044-a-1#264,NA,NA,p.Pro7Asn,0.03,-0.03,2,P337N +urn:mavedb:00000044-a-1#265,NA,NA,p.Pro7Gln,0.01,-0.21,1,P337Q +urn:mavedb:00000044-a-1#266,NA,NA,p.Pro7Gln,-0.43,-0.21,2,P337Q +urn:mavedb:00000044-a-1#267,NA,NA,p.Pro7Arg,-0.16,-0.14,1,P337R +urn:mavedb:00000044-a-1#268,NA,NA,p.Pro7Arg,-0.12,-0.14,2,P337R +urn:mavedb:00000044-a-1#269,NA,NA,p.Pro7Ser,-0.1,-0.1,1,P337S +urn:mavedb:00000044-a-1#270,NA,NA,p.Pro7Ser,-0.1,-0.1,2,P337S +urn:mavedb:00000044-a-1#271,NA,NA,p.Pro7Thr,-0.13,-0.13,1,P337T +urn:mavedb:00000044-a-1#272,NA,NA,p.Pro7Thr,-0.14,-0.13,2,P337T +urn:mavedb:00000044-a-1#273,NA,NA,p.Pro7Val,-0.38,-0.4,1,P337V +urn:mavedb:00000044-a-1#274,NA,NA,p.Pro7Val,-0.41,-0.4,2,P337V +urn:mavedb:00000044-a-1#275,NA,NA,p.Pro7Trp,-0.42,-0.4,1,P337W +urn:mavedb:00000044-a-1#276,NA,NA,p.Pro7Trp,-0.38,-0.4,2,P337W +urn:mavedb:00000044-a-1#277,NA,NA,p.Pro7Tyr,-0.25,-0.26,1,P337Y +urn:mavedb:00000044-a-1#278,NA,NA,p.Pro7Tyr,-0.26,-0.26,2,P337Y +urn:mavedb:00000044-a-1#279,NA,NA,p.Pro7*,NA,NA,1,P337 +urn:mavedb:00000044-a-1#280,NA,NA,p.Pro7*,NA,NA,2,P337 +urn:mavedb:00000044-a-1#281,NA,NA,p.Phe8Ala,-0.88,-0.97,1,F338A +urn:mavedb:00000044-a-1#282,NA,NA,p.Phe8Ala,-1.06,-0.97,2,F338A +urn:mavedb:00000044-a-1#283,NA,NA,p.Phe8Cys,-0.92,-0.95,1,F338C +urn:mavedb:00000044-a-1#284,NA,NA,p.Phe8Cys,-0.99,-0.95,2,F338C +urn:mavedb:00000044-a-1#285,NA,NA,p.Phe8Asp,-1.07,-1.11,1,F338D +urn:mavedb:00000044-a-1#286,NA,NA,p.Phe8Asp,-1.15,-1.11,2,F338D +urn:mavedb:00000044-a-1#287,NA,NA,p.Phe8Glu,-0.88,-1.04,1,F338E +urn:mavedb:00000044-a-1#288,NA,NA,p.Phe8Glu,-1.2,-1.04,2,F338E +urn:mavedb:00000044-a-1#289,NA,NA,p.Phe8Gly,-0.99,-1.08,1,F338G +urn:mavedb:00000044-a-1#290,NA,NA,p.Phe8Gly,-1.17,-1.08,2,F338G +urn:mavedb:00000044-a-1#302,NA,NA,p.Phe8Asn,-1.22,-1.13,2,F338N +urn:mavedb:00000044-a-1#311,NA,NA,p.Phe8Thr,-0.94,-0.93,1,F338T +urn:mavedb:00000044-a-1#312,NA,NA,p.Phe8Thr,-0.92,-0.93,2,F338T +urn:mavedb:00000044-a-1#313,NA,NA,p.Phe8Val,-0.53,-0.55,1,F338V +urn:mavedb:00000044-a-1#314,NA,NA,p.Phe8Val,-0.56,-0.55,2,F338V +urn:mavedb:00000044-a-1#315,NA,NA,p.Phe8Trp,0.05,0.04,1,F338W +urn:mavedb:00000044-a-1#316,NA,NA,p.Phe8Trp,0.04,0.04,2,F338W +urn:mavedb:00000044-a-1#317,NA,NA,p.Phe8Tyr,-0.05,-0.05,1,F338Y +urn:mavedb:00000044-a-1#477,NA,NA,p.Phe12Tyr,-0.79,-0.89,1,F342Y +urn:mavedb:00000044-a-1#478,NA,NA,p.Phe12Tyr,-1,-0.89,2,F342Y +urn:mavedb:00000044-a-1#479,NA,NA,p.Phe12*,NA,NA,1,F342 +urn:mavedb:00000044-a-1#480,NA,NA,p.Phe12*,NA,NA,2,F342 +urn:mavedb:00000044-a-1#481,NA,NA,p.Asn13Ala,-0.36,-0.38,1,N343A +urn:mavedb:00000044-a-1#482,NA,NA,p.Asn13Ala,-0.41,-0.38,2,N343A +urn:mavedb:00000044-a-1#483,NA,NA,p.Asn13Cys,-0.76,-0.76,1,N343C +urn:mavedb:00000044-a-1#484,NA,NA,p.Asn13Cys,-0.75,-0.76,2,N343C +urn:mavedb:00000044-a-1#485,NA,NA,p.Asn13Asp,-0.37,-0.37,1,N343D +urn:mavedb:00000044-a-1#486,NA,NA,p.Asn13Asp,-0.37,-0.37,2,N343D +urn:mavedb:00000044-a-1#487,NA,NA,p.Asn13Glu,-0.27,-0.25,1,N343E +urn:mavedb:00000044-a-1#488,NA,NA,p.Asn13Glu,-0.23,-0.25,2,N343E +urn:mavedb:00000044-a-1#489,NA,NA,p.Asn13Phe,-0.39,-0.45,1,N343F +urn:mavedb:00000044-a-1#490,NA,NA,p.Asn13Phe,-0.51,-0.45,2,N343F +urn:mavedb:00000044-a-1#491,NA,NA,p.Asn13Gly,-0.18,-0.2,1,N343G +urn:mavedb:00000044-a-1#509,NA,NA,p.Asn13Ser,-0.34,-0.32,1,N343S +urn:mavedb:00000044-a-1#510,NA,NA,p.Asn13Ser,-0.31,-0.32,2,N343S +urn:mavedb:00000044-a-1#511,NA,NA,p.Asn13Thr,-0.35,-0.35,1,N343T +urn:mavedb:00000044-a-1#512,NA,NA,p.Asn13Thr,-0.35,-0.35,2,N343T +urn:mavedb:00000044-a-1#513,NA,NA,p.Asn13Val,-0.72,-0.82,1,N343V +urn:mavedb:00000044-a-1#514,NA,NA,p.Asn13Val,-0.92,-0.82,2,N343V +urn:mavedb:00000044-a-1#515,NA,NA,p.Asn13Trp,-0.46,-0.5,1,N343W +urn:mavedb:00000044-a-1#516,NA,NA,p.Asn13Trp,-0.54,-0.5,2,N343W +urn:mavedb:00000044-a-1#517,NA,NA,p.Asn13Tyr,-0.48,-0.46,1,N343Y +urn:mavedb:00000044-a-1#549,NA,NA,p.Ala14Ser,-0.15,-0.14,1,A344S +urn:mavedb:00000044-a-1#550,NA,NA,p.Ala14Ser,-0.13,-0.14,2,A344S +urn:mavedb:00000044-a-1#551,NA,NA,p.Ala14Thr,-0.35,-0.37,1,A344T +urn:mavedb:00000044-a-1#552,NA,NA,p.Ala14Thr,-0.38,-0.37,2,A344T +urn:mavedb:00000044-a-1#553,NA,NA,p.Ala14Val,-0.43,-0.46,1,A344V +urn:mavedb:00000044-a-1#554,NA,NA,p.Ala14Val,-0.49,-0.46,2,A344V +urn:mavedb:00000044-a-1#555,NA,NA,p.Ala14Trp,-0.86,-0.92,1,A344W +urn:mavedb:00000044-a-1#556,NA,NA,p.Ala14Trp,-0.98,-0.92,2,A344W +urn:mavedb:00000044-a-1#557,NA,NA,p.Ala14Tyr,-0.74,-0.81,1,A344Y +urn:mavedb:00000044-a-1#558,NA,NA,p.Ala14Tyr,-0.88,-0.81,2,A344Y +urn:mavedb:00000044-a-1#559,NA,NA,p.Ala14*,NA,NA,1,A344 +urn:mavedb:00000044-a-1#560,NA,NA,p.Ala14*,NA,NA,2,A344 +urn:mavedb:00000044-a-1#561,NA,NA,p.Thr15Ala,-0.11,-0.12,1,T345A +urn:mavedb:00000044-a-1#562,NA,NA,p.Thr15Ala,-0.13,-0.12,2,T345A +urn:mavedb:00000044-a-1#563,NA,NA,p.Thr15Cys,-0.58,-0.64,1,T345C +urn:mavedb:00000044-a-1#582,NA,NA,p.Thr15Met,-0.39,-0.37,2,T345M +urn:mavedb:00000044-a-1#583,NA,NA,p.Thr15Asn,-0.18,-0.21,1,T345N +urn:mavedb:00000044-a-1#584,NA,NA,p.Thr15Asn,-0.23,-0.21,2,T345N +urn:mavedb:00000044-a-1#585,NA,NA,p.Thr15Pro,-0.08,-0.06,1,T345P +urn:mavedb:00000044-a-1#586,NA,NA,p.Thr15Pro,-0.04,-0.06,2,T345P +urn:mavedb:00000044-a-1#587,NA,NA,p.Thr15Gln,-0.14,-0.15,1,T345Q +urn:mavedb:00000044-a-1#588,NA,NA,p.Thr15Gln,-0.15,-0.15,2,T345Q +urn:mavedb:00000044-a-1#589,NA,NA,p.Thr15Arg,-0.12,-0.13,1,T345R +urn:mavedb:00000044-a-1#590,NA,NA,p.Thr15Arg,-0.14,-0.13,2,T345R +urn:mavedb:00000044-a-1#591,NA,NA,p.Thr15Ser,-0.03,-0.02,1,T345S +urn:mavedb:00000044-a-1#592,NA,NA,p.Thr15Ser,-0.02,-0.02,2,T345S +urn:mavedb:00000044-a-1#606,NA,NA,p.Arg16Asp,0.04,0.01,2,R346D +urn:mavedb:00000044-a-1#607,NA,NA,p.Arg16Glu,0,0,1,R346E +urn:mavedb:00000044-a-1#608,NA,NA,p.Arg16Glu,0.01,0,2,R346E +urn:mavedb:00000044-a-1#609,NA,NA,p.Arg16Phe,-0.03,-0.02,1,R346F +urn:mavedb:00000044-a-1#610,NA,NA,p.Arg16Phe,-0.02,-0.02,2,R346F +urn:mavedb:00000044-a-1#611,NA,NA,p.Arg16Gly,-0.08,-0.11,1,R346G +urn:mavedb:00000044-a-1#612,NA,NA,p.Arg16Gly,-0.14,-0.11,2,R346G +urn:mavedb:00000044-a-1#613,NA,NA,p.Arg16His,0.15,0.08,1,R346H +urn:mavedb:00000044-a-1#614,NA,NA,p.Arg16His,0.02,0.08,2,R346H +urn:mavedb:00000044-a-1#615,NA,NA,p.Arg16Ile,0.04,-0.01,1,R346I +urn:mavedb:00000044-a-1#616,NA,NA,p.Arg16Ile,-0.05,-0.01,2,R346I +urn:mavedb:00000044-a-1#617,NA,NA,p.Arg16Lys,-0.04,-0.01,1,R346K +urn:mavedb:00000044-a-1#618,NA,NA,p.Arg16Lys,0.02,-0.01,2,R346K +urn:mavedb:00000044-a-1#637,NA,NA,p.Arg16Tyr,0.07,0.07,1,R346Y +urn:mavedb:00000044-a-1#640,NA,NA,p.Arg16*,NA,NA,2,R346 +urn:mavedb:00000044-a-1#641,NA,NA,p.Phe17Ala,-0.81,-0.87,1,F347A +urn:mavedb:00000044-a-1#642,NA,NA,p.Phe17Ala,-0.93,-0.87,2,F347A +urn:mavedb:00000044-a-1#643,NA,NA,p.Phe17Cys,-0.86,-1,1,F347C +urn:mavedb:00000044-a-1#644,NA,NA,p.Phe17Cys,-1.14,-1,2,F347C +urn:mavedb:00000044-a-1#765,NA,NA,p.Val20Asp,-4.76,-4.8,1,V350D +urn:mavedb:00000044-a-1#766,NA,NA,p.Val20Asp,-4.84,-4.8,2,V350D +urn:mavedb:00000044-a-1#767,NA,NA,p.Val20Glu,-4.5,-4.59,1,V350E +urn:mavedb:00000044-a-1#768,NA,NA,p.Val20Glu,-4.67,-4.59,2,V350E +urn:mavedb:00000044-a-1#769,NA,NA,p.Val20Phe,NA,-4.84,1,V350F +urn:mavedb:00000044-a-1#770,NA,NA,p.Val20Phe,-4.84,-4.84,2,V350F +urn:mavedb:00000044-a-1#776,NA,NA,p.Val20Ile,-0.02,-0.23,2,V350I +urn:mavedb:00000044-a-1#777,NA,NA,p.Val20Lys,-4.76,-4.8,1,V350K +urn:mavedb:00000044-a-1#778,NA,NA,p.Val20Lys,-4.84,-4.8,2,V350K +urn:mavedb:00000044-a-1#779,NA,NA,p.Val20Leu,-1.7,-1.69,1,V350L +urn:mavedb:00000044-a-1#780,NA,NA,p.Val20Leu,-1.67,-1.69,2,V350L +urn:mavedb:00000044-a-1#781,NA,NA,p.Val20Met,-4.11,-3.54,1,V350M +urn:mavedb:00000044-a-1#782,NA,NA,p.Val20Met,-2.96,-3.54,2,V350M +urn:mavedb:00000044-a-1#783,NA,NA,p.Val20Asn,-3.3,-2.44,1,V350N +urn:mavedb:00000044-a-1#784,NA,NA,p.Val20Asn,-1.58,-2.44,2,V350N +urn:mavedb:00000044-a-1#785,NA,NA,p.Val20Pro,-0.1,-0.22,1,V350P +urn:mavedb:00000044-a-1#786,NA,NA,p.Val20Pro,-0.33,-0.22,2,V350P +urn:mavedb:00000044-a-1#787,NA,NA,p.Val20Gln,-3.35,-4.1,1,V350Q +urn:mavedb:00000044-a-1#788,NA,NA,p.Val20Gln,-4.84,-4.1,2,V350Q +urn:mavedb:00000044-a-1#789,NA,NA,p.Val20Arg,-4.76,-4.8,1,V350R +urn:mavedb:00000044-a-1#805,NA,NA,p.Tyr21Asp,-2.25,-2.72,1,Y351D +urn:mavedb:00000044-a-1#806,NA,NA,p.Tyr21Asp,-3.19,-2.72,2,Y351D +urn:mavedb:00000044-a-1#807,NA,NA,p.Tyr21Glu,-1.32,-1.5,1,Y351E +urn:mavedb:00000044-a-1#808,NA,NA,p.Tyr21Glu,-1.68,-1.5,2,Y351E +urn:mavedb:00000044-a-1#809,NA,NA,p.Tyr21Phe,-0.12,-0.08,1,Y351F +urn:mavedb:00000044-a-1#810,NA,NA,p.Tyr21Phe,-0.05,-0.08,2,Y351F +urn:mavedb:00000044-a-1#811,NA,NA,p.Tyr21Gly,-1.81,-1.65,1,Y351G +urn:mavedb:00000044-a-1#812,NA,NA,p.Tyr21Gly,-1.49,-1.65,2,Y351G +urn:mavedb:00000044-a-1#813,NA,NA,p.Tyr21His,-0.31,-0.27,1,Y351H +urn:mavedb:00000044-a-1#814,NA,NA,p.Tyr21His,-0.23,-0.27,2,Y351H +urn:mavedb:00000044-a-1#815,NA,NA,p.Tyr21Ile,-0.76,-0.79,1,Y351I +urn:mavedb:00000044-a-1#816,NA,NA,p.Tyr21Ile,-0.82,-0.79,2,Y351I +urn:mavedb:00000044-a-1#817,NA,NA,p.Tyr21Lys,-2.5,-2.5,1,Y351K +urn:mavedb:00000044-a-1#818,NA,NA,p.Tyr21Lys,-2.49,-2.5,2,Y351K +urn:mavedb:00000044-a-1#830,NA,NA,p.Tyr21Arg,-2.83,-2.97,2,Y351R +urn:mavedb:00000044-a-1#831,NA,NA,p.Tyr21Ser,-0.64,-0.71,1,Y351S +urn:mavedb:00000044-a-1#832,NA,NA,p.Tyr21Ser,-0.77,-0.71,2,Y351S +urn:mavedb:00000044-a-1#833,NA,NA,p.Tyr21Thr,-0.64,-0.82,1,Y351T +urn:mavedb:00000044-a-1#834,NA,NA,p.Tyr21Thr,-1,-0.82,2,Y351T +urn:mavedb:00000044-a-1#835,NA,NA,p.Tyr21Val,-0.19,-0.29,1,Y351V +urn:mavedb:00000044-a-1#836,NA,NA,p.Tyr21Val,-0.38,-0.29,2,Y351V +urn:mavedb:00000044-a-1#837,NA,NA,p.Tyr21Trp,-0.26,-0.19,1,Y351W +urn:mavedb:00000044-a-1#838,NA,NA,p.Tyr21Trp,-0.12,-0.19,2,Y351W +urn:mavedb:00000044-a-1#839,NA,NA,p.Tyr21*,NA,NA,1,Y351 +urn:mavedb:00000044-a-1#840,NA,NA,p.Tyr21*,NA,NA,2,Y351 +urn:mavedb:00000044-a-1#841,NA,NA,p.Ala22Cys,-0.12,-0.11,1,A352C +urn:mavedb:00000044-a-1#842,NA,NA,p.Ala22Cys,-0.1,-0.11,2,A352C +urn:mavedb:00000044-a-1#564,NA,NA,p.Thr15Cys,-0.69,-0.64,2,T345C +urn:mavedb:00000044-a-1#565,NA,NA,p.Thr15Asp,-0.11,-0.12,1,T345D +urn:mavedb:00000044-a-1#566,NA,NA,p.Thr15Asp,-0.12,-0.12,2,T345D +urn:mavedb:00000044-a-1#567,NA,NA,p.Thr15Glu,-0.06,-0.09,1,T345E +urn:mavedb:00000044-a-1#593,NA,NA,p.Thr15Val,-0.24,-0.28,1,T345V +urn:mavedb:00000044-a-1#594,NA,NA,p.Thr15Val,-0.31,-0.28,2,T345V +urn:mavedb:00000044-a-1#595,NA,NA,p.Thr15Trp,-0.59,-0.62,1,T345W +urn:mavedb:00000044-a-1#596,NA,NA,p.Thr15Trp,-0.65,-0.62,2,T345W +urn:mavedb:00000044-a-1#597,NA,NA,p.Thr15Tyr,-0.44,-0.48,1,T345Y +urn:mavedb:00000044-a-1#598,NA,NA,p.Thr15Tyr,-0.53,-0.48,2,T345Y +urn:mavedb:00000044-a-1#599,NA,NA,p.Thr15*,NA,NA,1,T345 +urn:mavedb:00000044-a-1#600,NA,NA,p.Thr15*,NA,NA,2,T345 +urn:mavedb:00000044-a-1#601,NA,NA,p.Arg16Ala,0.04,-0.02,1,R346A +urn:mavedb:00000044-a-1#602,NA,NA,p.Arg16Ala,-0.07,-0.02,2,R346A +urn:mavedb:00000044-a-1#603,NA,NA,p.Arg16Cys,-0.1,-0.12,1,R346C +urn:mavedb:00000044-a-1#604,NA,NA,p.Arg16Cys,-0.14,-0.12,2,R346C +urn:mavedb:00000044-a-1#605,NA,NA,p.Arg16Asp,-0.02,0.01,1,R346D +urn:mavedb:00000044-a-1#619,NA,NA,p.Arg16Leu,-0.05,-0.04,1,R346L +urn:mavedb:00000044-a-1#620,NA,NA,p.Arg16Leu,-0.03,-0.04,2,R346L +urn:mavedb:00000044-a-1#621,NA,NA,p.Arg16Met,0,-0.02,1,R346M +urn:mavedb:00000044-a-1#622,NA,NA,p.Arg16Met,-0.04,-0.02,2,R346M +urn:mavedb:00000044-a-1#623,NA,NA,p.Arg16Asn,0.08,0.03,1,R346N +urn:mavedb:00000044-a-1#624,NA,NA,p.Arg16Asn,-0.02,0.03,2,R346N +urn:mavedb:00000044-a-1#625,NA,NA,p.Arg16Pro,-0.38,-0.38,1,R346P +urn:mavedb:00000044-a-1#626,NA,NA,p.Arg16Pro,-0.37,-0.38,2,R346P +urn:mavedb:00000044-a-1#627,NA,NA,p.Arg16Gln,-0.02,-0.01,1,R346Q +urn:mavedb:00000044-a-1#628,NA,NA,p.Arg16Gln,0,-0.01,2,R346Q +urn:mavedb:00000044-a-1#629,NA,NA,p.Arg16Ser,0.07,0.04,1,R346S +urn:mavedb:00000044-a-1#630,NA,NA,p.Arg16Ser,0.02,0.04,2,R346S +urn:mavedb:00000044-a-1#631,NA,NA,p.Arg16Thr,0.06,0.06,1,R346T +urn:mavedb:00000044-a-1#632,NA,NA,p.Arg16Thr,0.06,0.06,2,R346T +urn:mavedb:00000044-a-1#633,NA,NA,p.Arg16Val,0.08,0.06,1,R346V +urn:mavedb:00000044-a-1#634,NA,NA,p.Arg16Val,0.04,0.06,2,R346V +urn:mavedb:00000044-a-1#635,NA,NA,p.Arg16Trp,-0.18,-0.06,1,R346W +urn:mavedb:00000044-a-1#638,NA,NA,p.Arg16Tyr,0.07,0.07,2,R346Y +urn:mavedb:00000044-a-1#636,NA,NA,p.Arg16Trp,0.06,-0.06,2,R346W +urn:mavedb:00000044-a-1#771,NA,NA,p.Val20Gly,-1.92,-1.9,1,V350G +urn:mavedb:00000044-a-1#772,NA,NA,p.Val20Gly,-1.88,-1.9,2,V350G +urn:mavedb:00000044-a-1#773,NA,NA,p.Val20His,-4.76,-4.8,1,V350H +urn:mavedb:00000044-a-1#774,NA,NA,p.Val20His,-4.84,-4.8,2,V350H +urn:mavedb:00000044-a-1#775,NA,NA,p.Val20Ile,-0.45,-0.23,1,V350I +urn:mavedb:00000044-a-1#790,NA,NA,p.Val20Arg,-4.84,-4.8,2,V350R +urn:mavedb:00000044-a-1#791,NA,NA,p.Val20Ser,-0.91,-0.94,1,V350S +urn:mavedb:00000044-a-1#792,NA,NA,p.Val20Ser,-0.97,-0.94,2,V350S +urn:mavedb:00000044-a-1#793,NA,NA,p.Val20Thr,-0.8,-0.8,1,V350T +urn:mavedb:00000044-a-1#794,NA,NA,p.Val20Thr,-0.8,-0.8,2,V350T +urn:mavedb:00000044-a-1#795,NA,NA,p.Val20Trp,-4.68,-4.71,1,V350W +urn:mavedb:00000044-a-1#796,NA,NA,p.Val20Trp,-4.73,-4.71,2,V350W +urn:mavedb:00000044-a-1#797,NA,NA,p.Val20Tyr,-4.15,-4.14,1,V350Y +urn:mavedb:00000044-a-1#798,NA,NA,p.Val20Tyr,-4.13,-4.14,2,V350Y +urn:mavedb:00000044-a-1#799,NA,NA,p.Val20*,NA,NA,1,V350 +urn:mavedb:00000044-a-1#800,NA,NA,p.Val20*,NA,NA,2,V350 +urn:mavedb:00000044-a-1#801,NA,NA,p.Tyr21Ala,-1.16,-0.87,1,Y351A +urn:mavedb:00000044-a-1#802,NA,NA,p.Tyr21Ala,-0.57,-0.87,2,Y351A +urn:mavedb:00000044-a-1#803,NA,NA,p.Tyr21Cys,-0.58,-0.6,1,Y351C +urn:mavedb:00000044-a-1#804,NA,NA,p.Tyr21Cys,-0.61,-0.6,2,Y351C +urn:mavedb:00000044-a-1#819,NA,NA,p.Tyr21Leu,-0.95,-0.92,1,Y351L +urn:mavedb:00000044-a-1#820,NA,NA,p.Tyr21Leu,-0.9,-0.92,2,Y351L +urn:mavedb:00000044-a-1#821,NA,NA,p.Tyr21Met,-0.55,-0.58,1,Y351M +urn:mavedb:00000044-a-1#822,NA,NA,p.Tyr21Met,-0.6,-0.58,2,Y351M +urn:mavedb:00000044-a-1#823,NA,NA,p.Tyr21Asn,-0.84,-0.77,1,Y351N +urn:mavedb:00000044-a-1#824,NA,NA,p.Tyr21Asn,-0.7,-0.77,2,Y351N +urn:mavedb:00000044-a-1#825,NA,NA,p.Tyr21Pro,-0.57,-0.81,1,Y351P +urn:mavedb:00000044-a-1#826,NA,NA,p.Tyr21Pro,-1.06,-0.81,2,Y351P +urn:mavedb:00000044-a-1#827,NA,NA,p.Tyr21Gln,-1.11,-1.01,1,Y351Q +urn:mavedb:00000044-a-1#828,NA,NA,p.Tyr21Gln,-0.9,-1.01,2,Y351Q +urn:mavedb:00000044-a-1#829,NA,NA,p.Tyr21Arg,-3.12,-2.97,1,Y351R +urn:mavedb:00000044-a-1#848,NA,NA,p.Ala22Phe,-0.26,-0.29,2,A352F +urn:mavedb:00000044-a-1#849,NA,NA,p.Ala22Gly,-0.2,-0.19,1,A352G +urn:mavedb:00000044-a-1#850,NA,NA,p.Ala22Gly,-0.18,-0.19,2,A352G +urn:mavedb:00000044-a-1#851,NA,NA,p.Ala22His,-0.02,-0.06,1,A352H +urn:mavedb:00000044-a-1#852,NA,NA,p.Ala22His,-0.1,-0.06,2,A352H +urn:mavedb:00000044-a-1#853,NA,NA,p.Ala22Ile,-0.51,-0.49,1,A352I +urn:mavedb:00000044-a-1#854,NA,NA,p.Ala22Ile,-0.47,-0.49,2,A352I +urn:mavedb:00000044-a-1#855,NA,NA,p.Ala22Lys,-0.03,-0.08,1,A352K +urn:mavedb:00000044-a-1#856,NA,NA,p.Ala22Lys,-0.12,-0.08,2,A352K +urn:mavedb:00000044-a-1#857,NA,NA,p.Ala22Leu,-0.29,-0.31,1,A352L +urn:mavedb:00000044-a-1#858,NA,NA,p.Ala22Leu,-0.34,-0.31,2,A352L +urn:mavedb:00000044-a-1#859,NA,NA,p.Ala22Met,0.01,-0.02,1,A352M +urn:mavedb:00000044-a-1#396,NA,NA,p.Glu10Trp,-0.7,-0.63,2,E340W +urn:mavedb:00000044-a-1#397,NA,NA,p.Glu10Tyr,-0.52,-0.55,1,E340Y +urn:mavedb:00000044-a-1#656,NA,NA,p.Phe17Lys,-1.52,-1.6,2,F347K +urn:mavedb:00000044-a-1#398,NA,NA,p.Glu10Tyr,-0.58,-0.55,2,E340Y +urn:mavedb:00000044-a-1#399,NA,NA,p.Glu10*,NA,NA,1,E340 +urn:mavedb:00000044-a-1#400,NA,NA,p.Glu10*,NA,NA,2,E340 +urn:mavedb:00000044-a-1#410,NA,NA,p.Val11Phe,-0.46,-0.51,2,V341F +urn:mavedb:00000044-a-1#411,NA,NA,p.Val11Gly,-1.02,-1.06,1,V341G +urn:mavedb:00000044-a-1#412,NA,NA,p.Val11Gly,-1.09,-1.06,2,V341G +urn:mavedb:00000044-a-1#413,NA,NA,p.Val11His,-1.05,-0.99,1,V341H +urn:mavedb:00000044-a-1#414,NA,NA,p.Val11His,-0.92,-0.99,2,V341H +urn:mavedb:00000044-a-1#415,NA,NA,p.Val11Ile,0.03,0.02,1,V341I +urn:mavedb:00000044-a-1#416,NA,NA,p.Val11Ile,0.01,0.02,2,V341I +urn:mavedb:00000044-a-1#291,NA,NA,p.Phe8His,-0.89,-0.97,1,F338H +urn:mavedb:00000044-a-1#292,NA,NA,p.Phe8His,-1.06,-0.97,2,F338H +urn:mavedb:00000044-a-1#293,NA,NA,p.Phe8Ile,-0.17,-0.15,1,F338I +urn:mavedb:00000044-a-1#294,NA,NA,p.Phe8Ile,-0.14,-0.15,2,F338I +urn:mavedb:00000044-a-1#295,NA,NA,p.Phe8Lys,-1.52,-1.49,1,F338K +urn:mavedb:00000044-a-1#657,NA,NA,p.Phe17Leu,-0.82,-0.87,1,F347L +urn:mavedb:00000044-a-1#658,NA,NA,p.Phe17Leu,-0.93,-0.87,2,F347L +urn:mavedb:00000044-a-1#659,NA,NA,p.Phe17Met,-0.43,-0.43,1,F347M +urn:mavedb:00000044-a-1#660,NA,NA,p.Phe17Met,-0.44,-0.43,2,F347M +urn:mavedb:00000044-a-1#661,NA,NA,p.Phe17Asn,-1.72,-2.15,1,F347N +urn:mavedb:00000044-a-1#662,NA,NA,p.Phe17Asn,-2.58,-2.15,2,F347N +urn:mavedb:00000044-a-1#663,NA,NA,p.Phe17Pro,-0.68,-0.75,1,F347P +urn:mavedb:00000044-a-1#664,NA,NA,p.Phe17Pro,-0.82,-0.75,2,F347P +urn:mavedb:00000044-a-1#665,NA,NA,p.Phe17Gln,-1.01,-1.04,1,F347Q +urn:mavedb:00000044-a-1#666,NA,NA,p.Phe17Gln,-1.06,-1.04,2,F347Q +urn:mavedb:00000044-a-1#667,NA,NA,p.Phe17Arg,-0.98,-1.17,1,F347R +urn:mavedb:00000044-a-1#668,NA,NA,p.Phe17Arg,-1.37,-1.17,2,F347R +urn:mavedb:00000044-a-1#669,NA,NA,p.Phe17Ser,-0.86,-0.89,1,F347S +urn:mavedb:00000044-a-1#670,NA,NA,p.Phe17Ser,-0.91,-0.89,2,F347S +urn:mavedb:00000044-a-1#671,NA,NA,p.Phe17Thr,-0.97,-1.08,1,F347T +urn:mavedb:00000044-a-1#672,NA,NA,p.Phe17Thr,-1.19,-1.08,2,F347T +urn:mavedb:00000044-a-1#673,NA,NA,p.Phe17Val,-0.66,-0.72,1,F347V +urn:mavedb:00000044-a-1#674,NA,NA,p.Phe17Val,-0.78,-0.72,2,F347V +urn:mavedb:00000044-a-1#675,NA,NA,p.Phe17Trp,0,0,1,F347W +urn:mavedb:00000044-a-1#676,NA,NA,p.Phe17Trp,0.01,0,2,F347W +urn:mavedb:00000044-a-1#677,NA,NA,p.Phe17Tyr,-0.25,-0.32,1,F347Y +urn:mavedb:00000044-a-1#678,NA,NA,p.Phe17Tyr,-0.39,-0.32,2,F347Y +urn:mavedb:00000044-a-1#679,NA,NA,p.Phe17*,NA,NA,1,F347 +urn:mavedb:00000044-a-1#680,NA,NA,p.Phe17*,NA,NA,2,F347 +urn:mavedb:00000044-a-1#681,NA,NA,p.Ala18Cys,-0.23,-0.26,1,A348C +urn:mavedb:00000044-a-1#682,NA,NA,p.Ala18Cys,-0.28,-0.26,2,A348C +urn:mavedb:00000044-a-1#683,NA,NA,p.Ala18Asp,-0.07,-0.07,1,A348D +urn:mavedb:00000044-a-1#684,NA,NA,p.Ala18Asp,-0.08,-0.07,2,A348D +urn:mavedb:00000044-a-1#685,NA,NA,p.Ala18Glu,-0.16,-0.13,1,A348E +urn:mavedb:00000044-a-1#686,NA,NA,p.Ala18Glu,-0.11,-0.13,2,A348E +urn:mavedb:00000044-a-1#687,NA,NA,p.Ala18Phe,-0.29,-0.29,1,A348F +urn:mavedb:00000044-a-1#688,NA,NA,p.Ala18Phe,-0.3,-0.29,2,A348F +urn:mavedb:00000044-a-1#707,NA,NA,p.Ala18Arg,-0.2,-0.24,1,A348R +urn:mavedb:00000044-a-1#708,NA,NA,p.Ala18Arg,-0.28,-0.24,2,A348R +urn:mavedb:00000044-a-1#709,NA,NA,p.Ala18Ser,0,0.01,1,A348S +urn:mavedb:00000044-a-1#710,NA,NA,p.Ala18Ser,0.02,0.01,2,A348S +urn:mavedb:00000044-a-1#711,NA,NA,p.Ala18Thr,-0.19,-0.18,1,A348T +urn:mavedb:00000044-a-1#712,NA,NA,p.Ala18Thr,-0.17,-0.18,2,A348T +urn:mavedb:00000044-a-1#713,NA,NA,p.Ala18Val,-0.55,-0.49,1,A348V +urn:mavedb:00000044-a-1#714,NA,NA,p.Ala18Val,-0.42,-0.49,2,A348V +urn:mavedb:00000044-a-1#715,NA,NA,p.Ala18Trp,-0.44,-0.46,1,A348W +urn:mavedb:00000044-a-1#716,NA,NA,p.Ala18Trp,-0.48,-0.46,2,A348W +urn:mavedb:00000044-a-1#717,NA,NA,p.Ala18Tyr,-0.1,-0.1,1,A348Y +urn:mavedb:00000044-a-1#718,NA,NA,p.Ala18Tyr,-0.11,-0.1,2,A348Y +urn:mavedb:00000044-a-1#719,NA,NA,p.Ala18*,NA,NA,1,A348 +urn:mavedb:00000044-a-1#720,NA,NA,p.Ala18*,NA,NA,2,A348 +urn:mavedb:00000044-a-1#417,NA,NA,p.Val11Lys,-1.97,-1.67,1,V341K +urn:mavedb:00000044-a-1#438,NA,NA,p.Val11Tyr,-0.71,-0.65,2,V341Y +urn:mavedb:00000044-a-1#439,NA,NA,p.Val11*,NA,NA,1,V341 +urn:mavedb:00000044-a-1#440,NA,NA,p.Val11*,NA,NA,2,V341 +urn:mavedb:00000044-a-1#441,NA,NA,p.Phe12Ala,-0.78,-0.99,1,F342A +urn:mavedb:00000044-a-1#442,NA,NA,p.Phe12Ala,-1.2,-0.99,2,F342A +urn:mavedb:00000044-a-1#443,NA,NA,p.Phe12Cys,-0.88,-1.01,1,F342C +urn:mavedb:00000044-a-1#444,NA,NA,p.Phe12Cys,-1.14,-1.01,2,F342C +urn:mavedb:00000044-a-1#445,NA,NA,p.Phe12Asp,-1.46,-1.55,1,F342D +urn:mavedb:00000044-a-1#446,NA,NA,p.Phe12Asp,-1.64,-1.55,2,F342D +urn:mavedb:00000044-a-1#447,NA,NA,p.Phe12Glu,-1.46,-1.51,1,F342E +urn:mavedb:00000044-a-1#448,NA,NA,p.Phe12Glu,-1.57,-1.51,2,F342E +urn:mavedb:00000044-a-1#449,NA,NA,p.Phe12Gly,-1.28,-1.41,1,F342G +urn:mavedb:00000044-a-1#450,NA,NA,p.Phe12Gly,-1.54,-1.41,2,F342G +urn:mavedb:00000044-a-1#451,NA,NA,p.Phe12His,-1.4,-1.54,1,F342H +urn:mavedb:00000044-a-1#843,NA,NA,p.Ala22Asp,-0.05,-0.03,1,A352D +urn:mavedb:00000044-a-1#844,NA,NA,p.Ala22Asp,-0.01,-0.03,2,A352D +urn:mavedb:00000044-a-1#845,NA,NA,p.Ala22Glu,-0.01,-0.03,1,A352E +urn:mavedb:00000044-a-1#846,NA,NA,p.Ala22Glu,-0.05,-0.03,2,A352E +urn:mavedb:00000044-a-1#847,NA,NA,p.Ala22Phe,-0.32,-0.29,1,A352F +urn:mavedb:00000044-a-1#884,NA,NA,p.Trp23Cys,-1.13,-1.22,2,W353C +urn:mavedb:00000044-a-1#885,NA,NA,p.Trp23Asp,-1.83,-2.39,1,W353D +urn:mavedb:00000044-a-1#886,NA,NA,p.Trp23Asp,-2.94,-2.39,2,W353D +urn:mavedb:00000044-a-1#887,NA,NA,p.Trp23Glu,-1.78,-1.83,1,W353E +urn:mavedb:00000044-a-1#888,NA,NA,p.Trp23Glu,-1.88,-1.83,2,W353E +urn:mavedb:00000044-a-1#889,NA,NA,p.Trp23Phe,-0.04,-0.08,1,W353F +urn:mavedb:00000044-a-1#890,NA,NA,p.Trp23Phe,-0.12,-0.08,2,W353F +urn:mavedb:00000044-a-1#891,NA,NA,p.Trp23Gly,-1.88,-2.17,1,W353G +urn:mavedb:00000044-a-1#892,NA,NA,p.Trp23Gly,-2.46,-2.17,2,W353G +urn:mavedb:00000044-a-1#893,NA,NA,p.Trp23His,-0.59,-0.95,1,W353H +urn:mavedb:00000044-a-1#900,NA,NA,p.Trp23Leu,-1.71,-2.15,2,W353L +urn:mavedb:00000044-a-1#901,NA,NA,p.Trp23Met,-2.77,-1.68,1,W353M +urn:mavedb:00000044-a-1#902,NA,NA,p.Trp23Met,-0.59,-1.68,2,W353M +urn:mavedb:00000044-a-1#903,NA,NA,p.Trp23Asn,-4.11,-2.68,1,W353N +urn:mavedb:00000044-a-1#904,NA,NA,p.Trp23Asn,-1.25,-2.68,2,W353N +urn:mavedb:00000044-a-1#905,NA,NA,p.Trp23Pro,-0.5,-0.62,1,W353P +urn:mavedb:00000044-a-1#906,NA,NA,p.Trp23Pro,-0.73,-0.62,2,W353P +urn:mavedb:00000044-a-1#907,NA,NA,p.Trp23Gln,-1.2,-1.36,1,W353Q +urn:mavedb:00000044-a-1#908,NA,NA,p.Trp23Gln,-1.52,-1.36,2,W353Q +urn:mavedb:00000044-a-1#909,NA,NA,p.Trp23Arg,-1.67,-1.62,1,W353R +urn:mavedb:00000044-a-1#910,NA,NA,p.Trp23Arg,-1.56,-1.62,2,W353R +urn:mavedb:00000044-a-1#911,NA,NA,p.Trp23Ser,-0.82,-0.98,1,W353S +urn:mavedb:00000044-a-1#912,NA,NA,p.Trp23Ser,-1.13,-0.98,2,W353S +urn:mavedb:00000044-a-1#913,NA,NA,p.Trp23Thr,-1.68,-2.75,1,W353T +urn:mavedb:00000044-a-1#914,NA,NA,p.Trp23Thr,-3.81,-2.75,2,W353T +urn:mavedb:00000044-a-1#915,NA,NA,p.Trp23Val,-1.17,-1.26,1,W353V +urn:mavedb:00000044-a-1#916,NA,NA,p.Trp23Val,-1.35,-1.26,2,W353V +urn:mavedb:00000044-a-1#917,NA,NA,p.Trp23Tyr,-0.3,-0.28,1,W353Y +urn:mavedb:00000044-a-1#918,NA,NA,p.Trp23Tyr,-0.27,-0.28,2,W353Y +urn:mavedb:00000044-a-1#919,NA,NA,p.Trp23*,NA,NA,1,W353 +urn:mavedb:00000044-a-1#920,NA,NA,p.Trp23*,NA,NA,2,W353 +urn:mavedb:00000044-a-1#921,NA,NA,p.Asn24Ala,-0.03,-0.04,1,N354A +urn:mavedb:00000044-a-1#922,NA,NA,p.Asn24Ala,-0.05,-0.04,2,N354A +urn:mavedb:00000044-a-1#923,NA,NA,p.Asn24Cys,-0.23,-0.29,1,N354C +urn:mavedb:00000044-a-1#736,NA,NA,p.Ser19Ile,-3.97,-4.25,2,S349I +urn:mavedb:00000044-a-1#737,NA,NA,p.Ser19Lys,-0.84,-0.87,1,S349K +urn:mavedb:00000044-a-1#738,NA,NA,p.Ser19Lys,-0.91,-0.87,2,S349K +urn:mavedb:00000044-a-1#739,NA,NA,p.Ser19Leu,-1.9,-1.91,1,S349L +urn:mavedb:00000044-a-1#740,NA,NA,p.Ser19Leu,-1.93,-1.91,2,S349L +urn:mavedb:00000044-a-1#741,NA,NA,p.Ser19Met,-0.77,-0.87,1,S349M +urn:mavedb:00000044-a-1#742,NA,NA,p.Ser19Met,-0.98,-0.87,2,S349M +urn:mavedb:00000044-a-1#743,NA,NA,p.Ser19Asn,-0.18,-0.26,1,S349N +urn:mavedb:00000044-a-1#744,NA,NA,p.Ser19Asn,-0.34,-0.26,2,S349N +urn:mavedb:00000044-a-1#745,NA,NA,p.Ser19Pro,-0.11,-0.11,1,S349P +urn:mavedb:00000044-a-1#746,NA,NA,p.Ser19Pro,-0.11,-0.11,2,S349P +urn:mavedb:00000044-a-1#747,NA,NA,p.Ser19Gln,-0.8,-0.83,1,S349Q +urn:mavedb:00000044-a-1#748,NA,NA,p.Ser19Gln,-0.85,-0.83,2,S349Q +urn:mavedb:00000044-a-1#749,NA,NA,p.Ser19Arg,-0.87,-0.96,1,S349R +urn:mavedb:00000044-a-1#750,NA,NA,p.Ser19Arg,-1.05,-0.96,2,S349R +urn:mavedb:00000044-a-1#751,NA,NA,p.Ser19Thr,-0.72,-0.76,1,S349T +urn:mavedb:00000044-a-1#752,NA,NA,p.Ser19Thr,-0.8,-0.76,2,S349T +urn:mavedb:00000044-a-1#757,NA,NA,p.Ser19Tyr,-1.72,-1.8,1,S349Y +urn:mavedb:00000044-a-1#758,NA,NA,p.Ser19Tyr,-1.87,-1.8,2,S349Y +urn:mavedb:00000044-a-1#759,NA,NA,p.Ser19*,NA,NA,1,S349 +urn:mavedb:00000044-a-1#760,NA,NA,p.Ser19*,NA,NA,2,S349 +urn:mavedb:00000044-a-1#761,NA,NA,p.Val20Ala,-0.33,-0.4,1,V350A +urn:mavedb:00000044-a-1#762,NA,NA,p.Val20Ala,-0.47,-0.4,2,V350A +urn:mavedb:00000044-a-1#763,NA,NA,p.Val20Cys,-2.38,-1.48,1,V350C +urn:mavedb:00000044-a-1#764,NA,NA,p.Val20Cys,-0.58,-1.48,2,V350C +urn:mavedb:00000044-a-1#162,NA,NA,p.Leu5Ala,0.05,0.04,2,L335A +urn:mavedb:00000044-a-1#163,NA,NA,p.Leu5Cys,-0.12,-0.11,1,L335C +urn:mavedb:00000044-a-1#164,NA,NA,p.Leu5Cys,-0.11,-0.11,2,L335C +urn:mavedb:00000044-a-1#165,NA,NA,p.Leu5Asp,0.04,0,1,L335D +urn:mavedb:00000044-a-1#166,NA,NA,p.Leu5Asp,-0.04,0,2,L335D +urn:mavedb:00000044-a-1#167,NA,NA,p.Leu5Glu,0.01,0.06,1,L335E +urn:mavedb:00000044-a-1#168,NA,NA,p.Leu5Glu,0.1,0.06,2,L335E +urn:mavedb:00000044-a-1#169,NA,NA,p.Leu5Phe,-0.04,-0.03,1,L335F +urn:mavedb:00000044-a-1#170,NA,NA,p.Leu5Phe,-0.02,-0.03,2,L335F +urn:mavedb:00000044-a-1#171,NA,NA,p.Leu5Gly,-0.01,-0.08,1,L335G +urn:mavedb:00000044-a-1#172,NA,NA,p.Leu5Gly,-0.16,-0.08,2,L335G +urn:mavedb:00000044-a-1#173,NA,NA,p.Leu5His,-0.01,-0.03,1,L335H +urn:mavedb:00000044-a-1#174,NA,NA,p.Leu5His,-0.05,-0.03,2,L335H +urn:mavedb:00000044-a-1#1320,NA,NA,p.Ala33*,NA,NA,2,A363 +urn:mavedb:00000044-a-1#2679,NA,NA,p.Ala67*,NA,NA,1,A397 +urn:mavedb:00000044-a-1#1640,NA,NA,p.Ser41*,NA,NA,2,S371 +urn:mavedb:00000044-a-1#2680,NA,NA,p.Ala67*,NA,NA,2,A397 +urn:mavedb:00000044-a-1#2648,NA,NA,p.Ala67Phe,-0.63,-0.47,2,A397F +urn:mavedb:00000044-a-1#1680,NA,NA,p.Ala42*,NA,NA,2,A372 +urn:mavedb:00000044-a-1#2641,NA,NA,p.Ala67Cys,-0.12,-0.13,1,A397C +urn:mavedb:00000044-a-1#865,NA,NA,p.Ala22Gln,0.04,-0.03,1,A352Q +urn:mavedb:00000044-a-1#866,NA,NA,p.Ala22Gln,-0.1,-0.03,2,A352Q +urn:mavedb:00000044-a-1#867,NA,NA,p.Ala22Arg,-0.04,-0.05,1,A352R +urn:mavedb:00000044-a-1#868,NA,NA,p.Ala22Arg,-0.05,-0.05,2,A352R +urn:mavedb:00000044-a-1#869,NA,NA,p.Ala22Ser,-0.03,-0.06,1,A352S +urn:mavedb:00000044-a-1#870,NA,NA,p.Ala22Ser,-0.08,-0.06,2,A352S +urn:mavedb:00000044-a-1#871,NA,NA,p.Ala22Thr,-0.2,-0.27,1,A352T +urn:mavedb:00000044-a-1#872,NA,NA,p.Ala22Thr,-0.34,-0.27,2,A352T +urn:mavedb:00000044-a-1#873,NA,NA,p.Ala22Val,-0.48,-0.52,1,A352V +urn:mavedb:00000044-a-1#874,NA,NA,p.Ala22Val,-0.55,-0.52,2,A352V +urn:mavedb:00000044-a-1#875,NA,NA,p.Ala22Trp,-0.42,-0.44,1,A352W +urn:mavedb:00000044-a-1#876,NA,NA,p.Ala22Trp,-0.46,-0.44,2,A352W +urn:mavedb:00000044-a-1#877,NA,NA,p.Ala22Tyr,-0.12,-0.14,1,A352Y +urn:mavedb:00000044-a-1#878,NA,NA,p.Ala22Tyr,-0.16,-0.14,2,A352Y +urn:mavedb:00000044-a-1#879,NA,NA,p.Ala22*,NA,NA,1,A352 +urn:mavedb:00000044-a-1#880,NA,NA,p.Ala22*,NA,NA,2,A352 +urn:mavedb:00000044-a-1#881,NA,NA,p.Trp23Ala,-1.7,-1.34,1,W353A +urn:mavedb:00000044-a-1#882,NA,NA,p.Trp23Ala,-0.98,-1.34,2,W353A +urn:mavedb:00000044-a-1#883,NA,NA,p.Trp23Cys,-1.31,-1.22,1,W353C +urn:mavedb:00000044-a-1#894,NA,NA,p.Trp23His,-1.3,-0.95,2,W353H +urn:mavedb:00000044-a-1#895,NA,NA,p.Trp23Ile,-2.34,-2.65,1,W353I +urn:mavedb:00000044-a-1#896,NA,NA,p.Trp23Ile,-2.97,-2.65,2,W353I +urn:mavedb:00000044-a-1#897,NA,NA,p.Trp23Lys,-2.09,-2.46,1,W353K +urn:mavedb:00000044-a-1#898,NA,NA,p.Trp23Lys,-2.83,-2.46,2,W353K +urn:mavedb:00000044-a-1#899,NA,NA,p.Trp23Leu,-2.59,-2.15,1,W353L +urn:mavedb:00000044-a-1#924,NA,NA,p.Asn24Cys,-0.35,-0.29,2,N354C +urn:mavedb:00000044-a-1#925,NA,NA,p.Asn24Asp,-0.09,-0.04,1,N354D +urn:mavedb:00000044-a-1#926,NA,NA,p.Asn24Asp,0.01,-0.04,2,N354D +urn:mavedb:00000044-a-1#721,NA,NA,p.Ser19Ala,-0.35,-0.34,1,S349A +urn:mavedb:00000044-a-1#722,NA,NA,p.Ser19Ala,-0.32,-0.34,2,S349A +urn:mavedb:00000044-a-1#723,NA,NA,p.Ser19Cys,0,-0.12,1,S349C +urn:mavedb:00000044-a-1#724,NA,NA,p.Ser19Cys,-0.24,-0.12,2,S349C +urn:mavedb:00000044-a-1#725,NA,NA,p.Ser19Asp,-0.48,-0.5,1,S349D +urn:mavedb:00000044-a-1#726,NA,NA,p.Ser19Asp,-0.52,-0.5,2,S349D +urn:mavedb:00000044-a-1#727,NA,NA,p.Ser19Glu,-1.08,-1.15,1,S349E +urn:mavedb:00000044-a-1#728,NA,NA,p.Ser19Glu,-1.23,-1.15,2,S349E +urn:mavedb:00000044-a-1#729,NA,NA,p.Ser19Phe,-1.96,-2.03,1,S349F +urn:mavedb:00000044-a-1#730,NA,NA,p.Ser19Phe,-2.11,-2.03,2,S349F +urn:mavedb:00000044-a-1#731,NA,NA,p.Ser19Gly,-0.52,-0.59,1,S349G +urn:mavedb:00000044-a-1#732,NA,NA,p.Ser19Gly,-0.66,-0.59,2,S349G +urn:mavedb:00000044-a-1#733,NA,NA,p.Ser19His,-1,-0.72,1,S349H +urn:mavedb:00000044-a-1#734,NA,NA,p.Ser19His,-0.45,-0.72,2,S349H +urn:mavedb:00000044-a-1#735,NA,NA,p.Ser19Ile,-4.53,-4.25,1,S349I +urn:mavedb:00000044-a-1#753,NA,NA,p.Ser19Val,-1.9,-1.92,1,S349V +urn:mavedb:00000044-a-1#754,NA,NA,p.Ser19Val,-1.94,-1.92,2,S349V +urn:mavedb:00000044-a-1#755,NA,NA,p.Ser19Trp,-2.19,-1.9,1,S349W +urn:mavedb:00000044-a-1#756,NA,NA,p.Ser19Trp,-1.61,-1.9,2,S349W +urn:mavedb:00000044-a-1#2638,NA,NA,p.Tyr66Trp,-0.06,-0.03,2,Y396W +urn:mavedb:00000044-a-1#2639,NA,NA,p.Tyr66*,NA,NA,1,Y396 +urn:mavedb:00000044-a-1#2640,NA,NA,p.Tyr66*,NA,NA,2,Y396 +urn:mavedb:00000044-a-1#2626,NA,NA,p.Tyr66Pro,-4.84,-4.8,2,Y396P +urn:mavedb:00000044-a-1#2627,NA,NA,p.Tyr66Gln,-0.12,-0.24,1,Y396Q +urn:mavedb:00000044-a-1#2628,NA,NA,p.Tyr66Gln,-0.36,-0.24,2,Y396Q +urn:mavedb:00000044-a-1#2629,NA,NA,p.Tyr66Arg,-0.6,-0.59,1,Y396R +urn:mavedb:00000044-a-1#2630,NA,NA,p.Tyr66Arg,-0.58,-0.59,2,Y396R +urn:mavedb:00000044-a-1#2631,NA,NA,p.Tyr66Ser,-0.34,-0.38,1,Y396S +urn:mavedb:00000044-a-1#2632,NA,NA,p.Tyr66Ser,-0.41,-0.38,2,Y396S +urn:mavedb:00000044-a-1#2633,NA,NA,p.Tyr66Thr,-0.02,-0.02,1,Y396T +urn:mavedb:00000044-a-1#2634,NA,NA,p.Tyr66Thr,-0.03,-0.02,2,Y396T +urn:mavedb:00000044-a-1#2635,NA,NA,p.Tyr66Val,-0.05,-0.06,1,Y396V +urn:mavedb:00000044-a-1#2636,NA,NA,p.Tyr66Val,-0.08,-0.06,2,Y396V +urn:mavedb:00000044-a-1#2637,NA,NA,p.Tyr66Trp,0,-0.03,1,Y396W +urn:mavedb:00000044-a-1#2650,NA,NA,p.Ala67Gly,-1.15,-1.07,2,A397G +urn:mavedb:00000044-a-1#2651,NA,NA,p.Ala67His,-1.58,-1.52,1,A397H +urn:mavedb:00000044-a-1#2652,NA,NA,p.Ala67His,-1.47,-1.52,2,A397H +urn:mavedb:00000044-a-1#2653,NA,NA,p.Ala67Ile,-0.23,-0.29,1,A397I +urn:mavedb:00000044-a-1#2654,NA,NA,p.Ala67Ile,-0.34,-0.29,2,A397I +urn:mavedb:00000044-a-1#2655,NA,NA,p.Ala67Lys,NA,NA,1,A397K +urn:mavedb:00000044-a-1#2656,NA,NA,p.Ala67Lys,NA,NA,2,A397K +urn:mavedb:00000044-a-1#2657,NA,NA,p.Ala67Leu,-0.07,-0.06,1,A397L +urn:mavedb:00000044-a-1#2658,NA,NA,p.Ala67Leu,-0.05,-0.06,2,A397L +urn:mavedb:00000044-a-1#2659,NA,NA,p.Ala67Met,NA,NA,1,A397M +urn:mavedb:00000044-a-1#2660,NA,NA,p.Ala67Met,NA,NA,2,A397M +urn:mavedb:00000044-a-1#2661,NA,NA,p.Ala67Asn,-4.11,-4.48,1,A397N +urn:mavedb:00000044-a-1#2662,NA,NA,p.Ala67Asn,-4.84,-4.48,2,A397N +urn:mavedb:00000044-a-1#2694,NA,NA,p.Asp68Ile,-3.74,-3.38,2,D398I +urn:mavedb:00000044-a-1#2690,NA,NA,p.Asp68Gly,-4.84,-4.76,2,D398G +urn:mavedb:00000044-a-1#2663,NA,NA,p.Ala67Pro,-4.05,-3.95,1,A397P +urn:mavedb:00000044-a-1#2691,NA,NA,p.Asp68His,-0.79,-0.85,1,D398H +urn:mavedb:00000044-a-1#2649,NA,NA,p.Ala67Gly,-0.98,-1.07,1,A397G +urn:mavedb:00000044-a-1#2839,NA,NA,p.Val71*,NA,NA,1,V401 +urn:mavedb:00000044-a-1#2840,NA,NA,p.Val71*,NA,NA,2,V401 +urn:mavedb:00000044-a-1#1879,NA,NA,p.Phe47*,NA,NA,1,F377 +urn:mavedb:00000044-a-1#2647,NA,NA,p.Ala67Phe,-0.32,-0.47,1,A397F +urn:mavedb:00000044-a-1#1880,NA,NA,p.Phe47*,NA,NA,2,F377 +urn:mavedb:00000044-a-1#2623,NA,NA,p.Tyr66Asn,-0.05,-0.07,1,Y396N +urn:mavedb:00000044-a-1#1919,NA,NA,p.Lys48*,NA,NA,1,K378 +urn:mavedb:00000044-a-1#2642,NA,NA,p.Ala67Cys,-0.14,-0.13,2,A397C +urn:mavedb:00000044-a-1#1920,NA,NA,p.Lys48*,NA,NA,2,K378 +urn:mavedb:00000044-a-1#2624,NA,NA,p.Tyr66Asn,-0.09,-0.07,2,Y396N +urn:mavedb:00000044-a-1#2625,NA,NA,p.Tyr66Pro,-4.76,-4.8,1,Y396P +urn:mavedb:00000044-a-1#2599,NA,NA,p.Val65*,NA,NA,1,V395 +urn:mavedb:00000044-a-1#2600,NA,NA,p.Val65*,NA,NA,2,V395 +urn:mavedb:00000044-a-1#2643,NA,NA,p.Ala67Asp,-3.89,-4.36,1,A397D +urn:mavedb:00000044-a-1#2644,NA,NA,p.Ala67Asp,-4.83,-4.36,2,A397D +urn:mavedb:00000044-a-1#2645,NA,NA,p.Ala67Glu,NA,NA,1,A397E +urn:mavedb:00000044-a-1#2646,NA,NA,p.Ala67Glu,NA,NA,2,A397E +urn:mavedb:00000044-a-1#2774,NA,NA,p.Phe70Ile,-4.84,-4.8,2,F400I +urn:mavedb:00000044-a-1#2775,NA,NA,p.Phe70Lys,-4.71,-4.72,1,F400K +urn:mavedb:00000044-a-1#2776,NA,NA,p.Phe70Lys,-4.73,-4.72,2,F400K +urn:mavedb:00000044-a-1#2777,NA,NA,p.Phe70Leu,-1.57,-1.61,1,F400L +urn:mavedb:00000044-a-1#2778,NA,NA,p.Phe70Leu,-1.65,-1.61,2,F400L +urn:mavedb:00000044-a-1#2779,NA,NA,p.Phe70Met,-0.69,-0.66,1,F400M +urn:mavedb:00000044-a-1#2780,NA,NA,p.Phe70Met,-0.63,-0.66,2,F400M +urn:mavedb:00000044-a-1#2781,NA,NA,p.Phe70Asn,-4.76,-4.8,1,F400N +urn:mavedb:00000044-a-1#2782,NA,NA,p.Phe70Asn,-4.84,-4.8,2,F400N +urn:mavedb:00000044-a-1#2783,NA,NA,p.Phe70Pro,-4.72,-4.78,1,F400P +urn:mavedb:00000044-a-1#2784,NA,NA,p.Phe70Pro,-4.84,-4.78,2,F400P +urn:mavedb:00000044-a-1#2785,NA,NA,p.Phe70Gln,-4.62,-4.38,1,F400Q +urn:mavedb:00000044-a-1#2786,NA,NA,p.Phe70Gln,-4.14,-4.38,2,F400Q +urn:mavedb:00000044-a-1#2787,NA,NA,p.Phe70Arg,-4.76,-4.8,1,F400R +urn:mavedb:00000044-a-1#2788,NA,NA,p.Phe70Arg,-4.84,-4.8,2,F400R +urn:mavedb:00000044-a-1#2789,NA,NA,p.Phe70Ser,-4.76,-4.8,1,F400S +urn:mavedb:00000044-a-1#2790,NA,NA,p.Phe70Ser,-4.84,-4.8,2,F400S +urn:mavedb:00000044-a-1#2791,NA,NA,p.Phe70Thr,-4.76,-4.8,1,F400T +urn:mavedb:00000044-a-1#2792,NA,NA,p.Phe70Thr,-4.84,-4.8,2,F400T +urn:mavedb:00000044-a-1#2793,NA,NA,p.Phe70Val,-4.46,-4.5,1,F400V +urn:mavedb:00000044-a-1#2676,NA,NA,p.Ala67Trp,NA,NA,2,A397W +urn:mavedb:00000044-a-1#2677,NA,NA,p.Ala67Tyr,-0.7,-0.67,1,A397Y +urn:mavedb:00000044-a-1#2692,NA,NA,p.Asp68His,-0.91,-0.85,2,D398H +urn:mavedb:00000044-a-1#2678,NA,NA,p.Ala67Tyr,-0.63,-0.67,2,A397Y +urn:mavedb:00000044-a-1#2664,NA,NA,p.Ala67Pro,-3.86,-3.95,2,A397P +urn:mavedb:00000044-a-1#2665,NA,NA,p.Ala67Gln,NA,NA,1,A397Q +urn:mavedb:00000044-a-1#2666,NA,NA,p.Ala67Gln,NA,NA,2,A397Q +urn:mavedb:00000044-a-1#2667,NA,NA,p.Ala67Arg,-3.25,-2.52,1,A397R +urn:mavedb:00000044-a-1#2668,NA,NA,p.Ala67Arg,-1.79,-2.52,2,A397R +urn:mavedb:00000044-a-1#2669,NA,NA,p.Ala67Ser,-0.6,-0.7,1,A397S +urn:mavedb:00000044-a-1#2670,NA,NA,p.Ala67Ser,-0.8,-0.7,2,A397S +urn:mavedb:00000044-a-1#2671,NA,NA,p.Ala67Thr,-0.44,-0.47,1,A397T +urn:mavedb:00000044-a-1#2672,NA,NA,p.Ala67Thr,-0.5,-0.47,2,A397T +urn:mavedb:00000044-a-1#2673,NA,NA,p.Ala67Val,-0.12,-0.15,1,A397V +urn:mavedb:00000044-a-1#2674,NA,NA,p.Ala67Val,-0.18,-0.15,2,A397V +urn:mavedb:00000044-a-1#2675,NA,NA,p.Ala67Trp,NA,NA,1,A397W +urn:mavedb:00000044-a-1#2681,NA,NA,p.Asp68Ala,-4.27,-4.34,1,D398A +urn:mavedb:00000044-a-1#2682,NA,NA,p.Asp68Ala,-4.42,-4.34,2,D398A +urn:mavedb:00000044-a-1#2683,NA,NA,p.Asp68Cys,-4.76,-4.53,1,D398C +urn:mavedb:00000044-a-1#2684,NA,NA,p.Asp68Cys,-4.31,-4.53,2,D398C +urn:mavedb:00000044-a-1#2685,NA,NA,p.Asp68Glu,-1.6,-1.59,1,D398E +urn:mavedb:00000044-a-1#2686,NA,NA,p.Asp68Glu,-1.58,-1.59,2,D398E +urn:mavedb:00000044-a-1#2687,NA,NA,p.Asp68Phe,-1.31,-1.72,1,D398F +urn:mavedb:00000044-a-1#2688,NA,NA,p.Asp68Phe,-2.12,-1.72,2,D398F +urn:mavedb:00000044-a-1#2689,NA,NA,p.Asp68Gly,-4.68,-4.76,1,D398G +urn:mavedb:00000044-a-1#2693,NA,NA,p.Asp68Ile,-3.02,-3.38,1,D398I +urn:mavedb:00000044-a-1#2695,NA,NA,p.Asp68Lys,-4.76,-4.8,1,D398K +urn:mavedb:00000044-a-1#2696,NA,NA,p.Asp68Lys,-4.84,-4.8,2,D398K +urn:mavedb:00000044-a-1#2697,NA,NA,p.Asp68Leu,-4.74,-4.79,1,D398L +urn:mavedb:00000044-a-1#2698,NA,NA,p.Asp68Leu,-4.84,-4.79,2,D398L +urn:mavedb:00000044-a-1#2703,NA,NA,p.Asp68Pro,-4.24,-4.54,1,D398P +urn:mavedb:00000044-a-1#2699,NA,NA,p.Asp68Met,-1.33,-1.39,1,D398M +urn:mavedb:00000044-a-1#2700,NA,NA,p.Asp68Met,-1.45,-1.39,2,D398M +urn:mavedb:00000044-a-1#2736,NA,NA,p.Ser69Ile,-1.11,-1.5,2,S399I +urn:mavedb:00000044-a-1#2702,NA,NA,p.Asp68Asn,-4.05,-3.46,2,D398N +urn:mavedb:00000044-a-1#2701,NA,NA,p.Asp68Asn,-2.87,-3.46,1,D398N +urn:mavedb:00000044-a-1#2704,NA,NA,p.Asp68Pro,-4.84,-4.54,2,D398P +urn:mavedb:00000044-a-1#2705,NA,NA,p.Asp68Gln,-4.23,-4.47,1,D398Q +urn:mavedb:00000044-a-1#2706,NA,NA,p.Asp68Gln,-4.7,-4.47,2,D398Q +urn:mavedb:00000044-a-1#2707,NA,NA,p.Asp68Arg,-4.76,-4.8,1,D398R +urn:mavedb:00000044-a-1#2708,NA,NA,p.Asp68Arg,-4.84,-4.8,2,D398R +urn:mavedb:00000044-a-1#2709,NA,NA,p.Asp68Ser,-1.97,-2.08,1,D398S +urn:mavedb:00000044-a-1#2710,NA,NA,p.Asp68Ser,-2.18,-2.08,2,D398S +urn:mavedb:00000044-a-1#2711,NA,NA,p.Asp68Thr,-1.14,-1.23,1,D398T +urn:mavedb:00000044-a-1#2712,NA,NA,p.Asp68Thr,-1.32,-1.23,2,D398T +urn:mavedb:00000044-a-1#2713,NA,NA,p.Asp68Val,-1.87,-2.08,1,D398V +urn:mavedb:00000044-a-1#2714,NA,NA,p.Asp68Val,-2.28,-2.08,2,D398V +urn:mavedb:00000044-a-1#2715,NA,NA,p.Asp68Trp,-3.66,-2.88,1,D398W +urn:mavedb:00000044-a-1#2716,NA,NA,p.Asp68Trp,-2.1,-2.88,2,D398W +urn:mavedb:00000044-a-1#2717,NA,NA,p.Asp68Tyr,-1,-1.09,1,D398Y +urn:mavedb:00000044-a-1#2718,NA,NA,p.Asp68Tyr,-1.18,-1.09,2,D398Y +urn:mavedb:00000044-a-1#2719,NA,NA,p.Asp68*,NA,NA,1,D398 +urn:mavedb:00000044-a-1#2720,NA,NA,p.Asp68*,NA,NA,2,D398 +urn:mavedb:00000044-a-1#2721,NA,NA,p.Ser69Ala,-0.31,-0.37,1,S399A +urn:mavedb:00000044-a-1#2722,NA,NA,p.Ser69Ala,-0.44,-0.37,2,S399A +urn:mavedb:00000044-a-1#2723,NA,NA,p.Ser69Cys,-0.97,-0.83,1,S399C +urn:mavedb:00000044-a-1#2724,NA,NA,p.Ser69Cys,-0.68,-0.83,2,S399C +urn:mavedb:00000044-a-1#2725,NA,NA,p.Ser69Asp,-1.2,-1.33,1,S399D +urn:mavedb:00000044-a-1#2726,NA,NA,p.Ser69Asp,-1.45,-1.33,2,S399D +urn:mavedb:00000044-a-1#2727,NA,NA,p.Ser69Glu,-1.48,-1.49,1,S399E +urn:mavedb:00000044-a-1#2728,NA,NA,p.Ser69Glu,-1.51,-1.49,2,S399E +urn:mavedb:00000044-a-1#2729,NA,NA,p.Ser69Phe,-0.35,-0.45,1,S399F +urn:mavedb:00000044-a-1#2730,NA,NA,p.Ser69Phe,-0.56,-0.45,2,S399F +urn:mavedb:00000044-a-1#2731,NA,NA,p.Ser69Gly,-0.83,-0.92,1,S399G +urn:mavedb:00000044-a-1#2732,NA,NA,p.Ser69Gly,-1.01,-0.92,2,S399G +urn:mavedb:00000044-a-1#2733,NA,NA,p.Ser69His,-3.16,-2,1,S399H +urn:mavedb:00000044-a-1#2734,NA,NA,p.Ser69His,-0.85,-2,2,S399H +urn:mavedb:00000044-a-1#2735,NA,NA,p.Ser69Ile,-1.88,-1.5,1,S399I +urn:mavedb:00000044-a-1#2737,NA,NA,p.Ser69Lys,-0.9,-0.97,1,S399K +urn:mavedb:00000044-a-1#2769,NA,NA,p.Phe70Gly,-4.76,-4.8,1,F400G +urn:mavedb:00000044-a-1#2756,NA,NA,p.Ser69Trp,-0.62,-0.52,2,S399W +urn:mavedb:00000044-a-1#2757,NA,NA,p.Ser69Tyr,-0.29,-0.3,1,S399Y +urn:mavedb:00000044-a-1#2770,NA,NA,p.Phe70Gly,-4.84,-4.8,2,F400G +urn:mavedb:00000044-a-1#2771,NA,NA,p.Phe70His,-4,-3.84,1,F400H +urn:mavedb:00000044-a-1#2738,NA,NA,p.Ser69Lys,-1.05,-0.97,2,S399K +urn:mavedb:00000044-a-1#2739,NA,NA,p.Ser69Leu,-0.82,-0.87,1,S399L +urn:mavedb:00000044-a-1#2740,NA,NA,p.Ser69Leu,-0.92,-0.87,2,S399L +urn:mavedb:00000044-a-1#2741,NA,NA,p.Ser69Met,-0.33,-0.35,1,S399M +urn:mavedb:00000044-a-1#2742,NA,NA,p.Ser69Met,-0.37,-0.35,2,S399M +urn:mavedb:00000044-a-1#2743,NA,NA,p.Ser69Asn,-0.31,-0.39,1,S399N +urn:mavedb:00000044-a-1#2744,NA,NA,p.Ser69Asn,-0.48,-0.39,2,S399N +urn:mavedb:00000044-a-1#2745,NA,NA,p.Ser69Pro,-3.03,-3.93,1,S399P +urn:mavedb:00000044-a-1#2746,NA,NA,p.Ser69Pro,-4.84,-3.93,2,S399P +urn:mavedb:00000044-a-1#2747,NA,NA,p.Ser69Gln,-0.37,-0.49,1,S399Q +urn:mavedb:00000044-a-1#2748,NA,NA,p.Ser69Gln,-0.61,-0.49,2,S399Q +urn:mavedb:00000044-a-1#2749,NA,NA,p.Ser69Arg,-0.6,-0.62,1,S399R +urn:mavedb:00000044-a-1#2750,NA,NA,p.Ser69Arg,-0.64,-0.62,2,S399R +urn:mavedb:00000044-a-1#2751,NA,NA,p.Ser69Thr,-0.08,-0.1,1,S399T +urn:mavedb:00000044-a-1#2752,NA,NA,p.Ser69Thr,-0.12,-0.1,2,S399T +urn:mavedb:00000044-a-1#2753,NA,NA,p.Ser69Val,-1.17,-1.26,1,S399V +urn:mavedb:00000044-a-1#2754,NA,NA,p.Ser69Val,-1.34,-1.26,2,S399V +urn:mavedb:00000044-a-1#2755,NA,NA,p.Ser69Trp,-0.42,-0.52,1,S399W +urn:mavedb:00000044-a-1#2758,NA,NA,p.Ser69Tyr,-0.31,-0.3,2,S399Y +urn:mavedb:00000044-a-1#2759,NA,NA,p.Ser69*,NA,NA,1,S399 +urn:mavedb:00000044-a-1#2760,NA,NA,p.Ser69*,NA,NA,2,S399 +urn:mavedb:00000044-a-1#2761,NA,NA,p.Phe70Ala,-4.76,-3.59,1,F400A +urn:mavedb:00000044-a-1#2762,NA,NA,p.Phe70Ala,-2.42,-3.59,2,F400A +urn:mavedb:00000044-a-1#2763,NA,NA,p.Phe70Cys,-4.37,-4.61,1,F400C +urn:mavedb:00000044-a-1#2764,NA,NA,p.Phe70Cys,-4.84,-4.61,2,F400C +urn:mavedb:00000044-a-1#2765,NA,NA,p.Phe70Asp,-4.76,-4.8,1,F400D +urn:mavedb:00000044-a-1#2766,NA,NA,p.Phe70Asp,-4.84,-4.8,2,F400D +urn:mavedb:00000044-a-1#2767,NA,NA,p.Phe70Glu,-4.25,-4.34,1,F400E +urn:mavedb:00000044-a-1#2768,NA,NA,p.Phe70Glu,-4.43,-4.34,2,F400E +urn:mavedb:00000044-a-1#2772,NA,NA,p.Phe70His,-3.68,-3.84,2,F400H +urn:mavedb:00000044-a-1#2773,NA,NA,p.Phe70Ile,-4.76,-4.8,1,F400I +urn:mavedb:00000044-a-1#3127,NA,NA,p.Gln79Glu,-0.19,-0.15,1,Q409E +urn:mavedb:00000044-a-1#3128,NA,NA,p.Gln79Glu,-0.12,-0.15,2,Q409E +urn:mavedb:00000044-a-1#3129,NA,NA,p.Gln79Phe,-0.4,-0.72,1,Q409F +urn:mavedb:00000044-a-1#3130,NA,NA,p.Gln79Phe,-1.05,-0.72,2,Q409F +urn:mavedb:00000044-a-1#3131,NA,NA,p.Gln79Gly,-0.88,-1,1,Q409G +urn:mavedb:00000044-a-1#3132,NA,NA,p.Gln79Gly,-1.11,-1,2,Q409G +urn:mavedb:00000044-a-1#3133,NA,NA,p.Gln79His,-0.61,-0.67,1,Q409H +urn:mavedb:00000044-a-1#3134,NA,NA,p.Gln79His,-0.73,-0.67,2,Q409H +urn:mavedb:00000044-a-1#3135,NA,NA,p.Gln79Ile,-2.07,-1.86,1,Q409I +urn:mavedb:00000044-a-1#3137,NA,NA,p.Gln79Lys,-0.63,-0.65,1,Q409K +urn:mavedb:00000044-a-1#3138,NA,NA,p.Gln79Lys,-0.68,-0.65,2,Q409K +urn:mavedb:00000044-a-1#3139,NA,NA,p.Gln79Leu,-0.72,-0.75,1,Q409L +urn:mavedb:00000044-a-1#3140,NA,NA,p.Gln79Leu,-0.79,-0.75,2,Q409L +urn:mavedb:00000044-a-1#3141,NA,NA,p.Gln79Met,-0.42,-0.54,1,Q409M +urn:mavedb:00000044-a-1#3142,NA,NA,p.Gln79Met,-0.65,-0.54,2,Q409M +urn:mavedb:00000044-a-1#3143,NA,NA,p.Gln79Asn,-0.59,-0.65,1,Q409N +urn:mavedb:00000044-a-1#3144,NA,NA,p.Gln79Asn,-0.71,-0.65,2,Q409N +urn:mavedb:00000044-a-1#3145,NA,NA,p.Gln79Pro,-4.76,-4.63,1,Q409P +urn:mavedb:00000044-a-1#3146,NA,NA,p.Gln79Pro,-4.49,-4.63,2,Q409P +urn:mavedb:00000044-a-1#3148,NA,NA,p.Gln79Arg,-0.87,-0.78,2,Q409R +urn:mavedb:00000044-a-1#3149,NA,NA,p.Gln79Ser,-0.58,-0.57,1,Q409S +urn:mavedb:00000044-a-1#3150,NA,NA,p.Gln79Ser,-0.55,-0.57,2,Q409S +urn:mavedb:00000044-a-1#3151,NA,NA,p.Gln79Thr,-0.65,-0.67,1,Q409T +urn:mavedb:00000044-a-1#3152,NA,NA,p.Gln79Thr,-0.7,-0.67,2,Q409T +urn:mavedb:00000044-a-1#3153,NA,NA,p.Gln79Val,-0.94,-1.06,1,Q409V +urn:mavedb:00000044-a-1#3154,NA,NA,p.Gln79Val,-1.17,-1.06,2,Q409V +urn:mavedb:00000044-a-1#3155,NA,NA,p.Gln79Trp,-0.74,-0.9,1,Q409W +urn:mavedb:00000044-a-1#3156,NA,NA,p.Gln79Trp,-1.06,-0.9,2,Q409W +urn:mavedb:00000044-a-1#3157,NA,NA,p.Gln79Tyr,NA,-0.45,1,Q409Y +urn:mavedb:00000044-a-1#3158,NA,NA,p.Gln79Tyr,-0.45,-0.45,2,Q409Y +urn:mavedb:00000044-a-1#3159,NA,NA,p.Gln79*,NA,NA,1,Q409 +urn:mavedb:00000044-a-1#3160,NA,NA,p.Gln79*,NA,NA,2,Q409 +urn:mavedb:00000044-a-1#3161,NA,NA,p.Ile80Ala,-4.4,-4.62,1,I410A +urn:mavedb:00000044-a-1#3162,NA,NA,p.Ile80Ala,-4.84,-4.62,2,I410A +urn:mavedb:00000044-a-1#3163,NA,NA,p.Ile80Cys,-0.75,-1.14,1,I410C +urn:mavedb:00000044-a-1#3164,NA,NA,p.Ile80Cys,-1.54,-1.14,2,I410C +urn:mavedb:00000044-a-1#3165,NA,NA,p.Ile80Asp,-3.98,-3.39,1,I410D +urn:mavedb:00000044-a-1#3166,NA,NA,p.Ile80Asp,-2.8,-3.39,2,I410D +urn:mavedb:00000044-a-1#3167,NA,NA,p.Ile80Glu,-4.76,-4.8,1,I410E +urn:mavedb:00000044-a-1#3168,NA,NA,p.Ile80Glu,-4.84,-4.8,2,I410E +urn:mavedb:00000044-a-1#3169,NA,NA,p.Ile80Phe,-3.46,-3.27,1,I410F +urn:mavedb:00000044-a-1#3170,NA,NA,p.Ile80Phe,-3.08,-3.27,2,I410F +urn:mavedb:00000044-a-1#3171,NA,NA,p.Ile80Gly,-4.76,-4.57,1,I410G +urn:mavedb:00000044-a-1#3172,NA,NA,p.Ile80Gly,-4.38,-4.57,2,I410G +urn:mavedb:00000044-a-1#3173,NA,NA,p.Ile80His,-4.76,-4.55,1,I410H +urn:mavedb:00000044-a-1#3174,NA,NA,p.Ile80His,-4.34,-4.55,2,I410H +urn:mavedb:00000044-a-1#3175,NA,NA,p.Ile80Lys,-4.63,-4.74,1,I410K +urn:mavedb:00000044-a-1#3176,NA,NA,p.Ile80Lys,-4.84,-4.74,2,I410K +urn:mavedb:00000044-a-1#3177,NA,NA,p.Ile80Leu,-0.33,-0.36,1,I410L +urn:mavedb:00000044-a-1#3178,NA,NA,p.Ile80Leu,-0.39,-0.36,2,I410L +urn:mavedb:00000044-a-1#3179,NA,NA,p.Ile80Met,-0.75,-0.72,1,I410M +urn:mavedb:00000044-a-1#3180,NA,NA,p.Ile80Met,-0.69,-0.72,2,I410M +urn:mavedb:00000044-a-1#3181,NA,NA,p.Ile80Asn,-3.01,-3.6,1,I410N +urn:mavedb:00000044-a-1#3182,NA,NA,p.Ile80Asn,-4.19,-3.6,2,I410N +urn:mavedb:00000044-a-1#3183,NA,NA,p.Ile80Pro,-4.76,-3.49,1,I410P +urn:mavedb:00000044-a-1#3184,NA,NA,p.Ile80Pro,-2.22,-3.49,2,I410P +urn:mavedb:00000044-a-1#3185,NA,NA,p.Ile80Gln,-4.76,-4.21,1,I410Q +urn:mavedb:00000044-a-1#3186,NA,NA,p.Ile80Gln,-3.66,-4.21,2,I410Q +urn:mavedb:00000044-a-1#3187,NA,NA,p.Ile80Arg,-4.76,-4.8,1,I410R +urn:mavedb:00000044-a-1#3188,NA,NA,p.Ile80Arg,-4.84,-4.8,2,I410R +urn:mavedb:00000044-a-1#3189,NA,NA,p.Ile80Ser,-4.76,-4.8,1,I410S +urn:mavedb:00000044-a-1#3190,NA,NA,p.Ile80Ser,-4.84,-4.8,2,I410S +urn:mavedb:00000044-a-1#3191,NA,NA,p.Ile80Thr,-4.13,-4.48,1,I410T +urn:mavedb:00000044-a-1#3192,NA,NA,p.Ile80Thr,-4.84,-4.48,2,I410T +urn:mavedb:00000044-a-1#3193,NA,NA,p.Ile80Val,-0.12,-0.11,1,I410V +urn:mavedb:00000044-a-1#3194,NA,NA,p.Ile80Val,-0.09,-0.11,2,I410V +urn:mavedb:00000044-a-1#3195,NA,NA,p.Ile80Trp,-4.75,-4.79,1,I410W +urn:mavedb:00000044-a-1#3196,NA,NA,p.Ile80Trp,-4.84,-4.79,2,I410W +urn:mavedb:00000044-a-1#3197,NA,NA,p.Ile80Tyr,-4.31,-4.18,1,I410Y +urn:mavedb:00000044-a-1#3198,NA,NA,p.Ile80Tyr,-4.05,-4.18,2,I410Y +urn:mavedb:00000044-a-1#3203,NA,NA,p.Ala81Asp,-0.66,-0.69,1,A411D +urn:mavedb:00000044-a-1#3199,NA,NA,p.Ile80*,NA,NA,1,I410 +urn:mavedb:00000044-a-1#3200,NA,NA,p.Ile80*,NA,NA,2,I410 +urn:mavedb:00000044-a-1#3201,NA,NA,p.Ala81Cys,-0.41,-0.4,1,A411C +urn:mavedb:00000044-a-1#3202,NA,NA,p.Ala81Cys,-0.4,-0.4,2,A411C +urn:mavedb:00000044-a-1#3204,NA,NA,p.Ala81Asp,-0.71,-0.69,2,A411D +urn:mavedb:00000044-a-1#3205,NA,NA,p.Ala81Glu,-0.09,-0.09,1,A411E +urn:mavedb:00000044-a-1#3206,NA,NA,p.Ala81Glu,-0.08,-0.09,2,A411E +urn:mavedb:00000044-a-1#3207,NA,NA,p.Ala81Phe,-0.81,-0.81,1,A411F +urn:mavedb:00000044-a-1#3208,NA,NA,p.Ala81Phe,-0.82,-0.81,2,A411F +urn:mavedb:00000044-a-1#3209,NA,NA,p.Ala81Gly,-0.07,-0.1,1,A411G +urn:mavedb:00000044-a-1#3210,NA,NA,p.Ala81Gly,-0.13,-0.1,2,A411G +urn:mavedb:00000044-a-1#3211,NA,NA,p.Ala81His,-0.55,-0.55,1,A411H +urn:mavedb:00000044-a-1#3212,NA,NA,p.Ala81His,-0.56,-0.55,2,A411H +urn:mavedb:00000044-a-1#3213,NA,NA,p.Ala81Ile,-0.65,-0.72,1,A411I +urn:mavedb:00000044-a-1#3214,NA,NA,p.Ala81Ile,-0.78,-0.72,2,A411I +urn:mavedb:00000044-a-1#3215,NA,NA,p.Ala81Lys,-0.3,-0.33,1,A411K +urn:mavedb:00000044-a-1#3216,NA,NA,p.Ala81Lys,-0.36,-0.33,2,A411K +urn:mavedb:00000044-a-1#3217,NA,NA,p.Ala81Leu,-0.69,-0.73,1,A411L +urn:mavedb:00000044-a-1#3218,NA,NA,p.Ala81Leu,-0.78,-0.73,2,A411L +urn:mavedb:00000044-a-1#3219,NA,NA,p.Ala81Met,-0.2,-0.29,1,A411M +urn:mavedb:00000044-a-1#3220,NA,NA,p.Ala81Met,-0.38,-0.29,2,A411M +urn:mavedb:00000044-a-1#3221,NA,NA,p.Ala81Asn,-0.52,-0.57,1,A411N +urn:mavedb:00000044-a-1#3222,NA,NA,p.Ala81Asn,-0.62,-0.57,2,A411N +urn:mavedb:00000044-a-1#3223,NA,NA,p.Ala81Pro,-4.34,-4.5,1,A411P +urn:mavedb:00000044-a-1#3224,NA,NA,p.Ala81Pro,-4.66,-4.5,2,A411P +urn:mavedb:00000044-a-1#3225,NA,NA,p.Ala81Gln,-0.04,-0.08,1,A411Q +urn:mavedb:00000044-a-1#3226,NA,NA,p.Ala81Gln,-0.11,-0.08,2,A411Q +urn:mavedb:00000044-a-1#3227,NA,NA,p.Ala81Arg,-0.17,-0.18,1,A411R +urn:mavedb:00000044-a-1#3228,NA,NA,p.Ala81Arg,-0.19,-0.18,2,A411R +urn:mavedb:00000044-a-1#3229,NA,NA,p.Ala81Ser,-0.11,-0.14,1,A411S +urn:mavedb:00000044-a-1#3230,NA,NA,p.Ala81Ser,-0.17,-0.14,2,A411S +urn:mavedb:00000044-a-1#3231,NA,NA,p.Ala81Thr,-0.58,-0.52,1,A411T +urn:mavedb:00000044-a-1#3232,NA,NA,p.Ala81Thr,-0.46,-0.52,2,A411T +urn:mavedb:00000044-a-1#3233,NA,NA,p.Ala81Val,-0.41,-0.4,1,A411V +urn:mavedb:00000044-a-1#3234,NA,NA,p.Ala81Val,-0.38,-0.4,2,A411V +urn:mavedb:00000044-a-1#3235,NA,NA,p.Ala81Trp,-0.2,-0.3,1,A411W +urn:mavedb:00000044-a-1#3236,NA,NA,p.Ala81Trp,-0.39,-0.3,2,A411W +urn:mavedb:00000044-a-1#3237,NA,NA,p.Ala81Tyr,-0.76,-0.93,1,A411Y +urn:mavedb:00000044-a-1#3238,NA,NA,p.Ala81Tyr,-1.09,-0.93,2,A411Y +urn:mavedb:00000044-a-1#3239,NA,NA,p.Ala81*,NA,NA,1,A411 +urn:mavedb:00000044-a-1#3240,NA,NA,p.Ala81*,NA,NA,2,A411 +urn:mavedb:00000044-a-1#3241,NA,NA,p.Pro82Ala,-1.09,-1.07,1,P412A +urn:mavedb:00000044-a-1#3242,NA,NA,p.Pro82Ala,-1.05,-1.07,2,P412A +urn:mavedb:00000044-a-1#3243,NA,NA,p.Pro82Cys,-2.77,-2.35,1,P412C +urn:mavedb:00000044-a-1#3244,NA,NA,p.Pro82Cys,-1.92,-2.35,2,P412C +urn:mavedb:00000044-a-1#3245,NA,NA,p.Pro82Asp,-3.2,-3.12,1,P412D +urn:mavedb:00000044-a-1#3246,NA,NA,p.Pro82Asp,-3.03,-3.12,2,P412D +urn:mavedb:00000044-a-1#3247,NA,NA,p.Pro82Glu,-1.65,-2.2,1,P412E +urn:mavedb:00000044-a-1#3248,NA,NA,p.Pro82Glu,-2.75,-2.2,2,P412E +urn:mavedb:00000044-a-1#3249,NA,NA,p.Pro82Phe,-3.92,-3.87,1,P412F +urn:mavedb:00000044-a-1#3250,NA,NA,p.Pro82Phe,-3.81,-3.87,2,P412F +urn:mavedb:00000044-a-1#3251,NA,NA,p.Pro82Gly,-1.49,-1.6,1,P412G +urn:mavedb:00000044-a-1#3252,NA,NA,p.Pro82Gly,-1.71,-1.6,2,P412G +urn:mavedb:00000044-a-1#3253,NA,NA,p.Pro82His,-1.62,-2.32,1,P412H +urn:mavedb:00000044-a-1#3254,NA,NA,p.Pro82His,-3.02,-2.32,2,P412H +urn:mavedb:00000044-a-1#3255,NA,NA,p.Pro82Ile,-0.96,-0.92,1,P412I +urn:mavedb:00000044-a-1#3256,NA,NA,p.Pro82Ile,-0.88,-0.92,2,P412I +urn:mavedb:00000044-a-1#3257,NA,NA,p.Pro82Lys,-0.88,-0.95,1,P412K +urn:mavedb:00000044-a-1#2794,NA,NA,p.Phe70Val,-4.54,-4.5,2,F400V +urn:mavedb:00000044-a-1#2795,NA,NA,p.Phe70Trp,-4.76,-4.77,1,F400W +urn:mavedb:00000044-a-1#2796,NA,NA,p.Phe70Trp,-4.78,-4.77,2,F400W +urn:mavedb:00000044-a-1#2797,NA,NA,p.Phe70Tyr,-0.81,-0.9,1,F400Y +urn:mavedb:00000044-a-1#2798,NA,NA,p.Phe70Tyr,-0.99,-0.9,2,F400Y +urn:mavedb:00000044-a-1#2799,NA,NA,p.Phe70*,NA,NA,1,F400 +urn:mavedb:00000044-a-1#2800,NA,NA,p.Phe70*,NA,NA,2,F400 +urn:mavedb:00000044-a-1#2801,NA,NA,p.Val71Ala,-0.53,-0.66,1,V401A +urn:mavedb:00000044-a-1#2802,NA,NA,p.Val71Ala,-0.79,-0.66,2,V401A +urn:mavedb:00000044-a-1#2803,NA,NA,p.Val71Cys,-0.71,-0.77,1,V401C +urn:mavedb:00000044-a-1#2804,NA,NA,p.Val71Cys,-0.82,-0.77,2,V401C +urn:mavedb:00000044-a-1#2805,NA,NA,p.Val71Asp,-4.53,-4.37,1,V401D +urn:mavedb:00000044-a-1#2806,NA,NA,p.Val71Asp,-4.21,-4.37,2,V401D +urn:mavedb:00000044-a-1#2807,NA,NA,p.Val71Glu,-4.15,-4.13,1,V401E +urn:mavedb:00000044-a-1#2808,NA,NA,p.Val71Glu,-4.12,-4.13,2,V401E +urn:mavedb:00000044-a-1#2809,NA,NA,p.Val71Phe,-3.38,-3.38,1,V401F +urn:mavedb:00000044-a-1#2833,NA,NA,p.Val71Thr,-0.41,-0.37,1,V401T +urn:mavedb:00000044-a-1#2834,NA,NA,p.Val71Thr,-0.32,-0.37,2,V401T +urn:mavedb:00000044-a-1#2822,NA,NA,p.Val71Met,-0.75,-0.64,2,V401M +urn:mavedb:00000044-a-1#2810,NA,NA,p.Val71Phe,NA,-3.38,2,V401F +urn:mavedb:00000044-a-1#2811,NA,NA,p.Val71Gly,-4.14,-4.32,1,V401G +urn:mavedb:00000044-a-1#2812,NA,NA,p.Val71Gly,-4.5,-4.32,2,V401G +urn:mavedb:00000044-a-1#2813,NA,NA,p.Val71His,-4.43,-4.63,1,V401H +urn:mavedb:00000044-a-1#2814,NA,NA,p.Val71His,-4.84,-4.63,2,V401H +urn:mavedb:00000044-a-1#2815,NA,NA,p.Val71Ile,-0.06,-0.26,1,V401I +urn:mavedb:00000044-a-1#2816,NA,NA,p.Val71Ile,-0.45,-0.26,2,V401I +urn:mavedb:00000044-a-1#2817,NA,NA,p.Val71Lys,-4.68,-4.76,1,V401K +urn:mavedb:00000044-a-1#2818,NA,NA,p.Val71Lys,-4.84,-4.76,2,V401K +urn:mavedb:00000044-a-1#2819,NA,NA,p.Val71Leu,-0.31,-0.33,1,V401L +urn:mavedb:00000044-a-1#2820,NA,NA,p.Val71Leu,-0.35,-0.33,2,V401L +urn:mavedb:00000044-a-1#2821,NA,NA,p.Val71Met,-0.52,-0.64,1,V401M +urn:mavedb:00000044-a-1#2823,NA,NA,p.Val71Asn,-4.46,-4.03,1,V401N +urn:mavedb:00000044-a-1#2824,NA,NA,p.Val71Asn,-3.6,-4.03,2,V401N +urn:mavedb:00000044-a-1#2825,NA,NA,p.Val71Pro,-4.76,-4.8,1,V401P +urn:mavedb:00000044-a-1#2826,NA,NA,p.Val71Pro,-4.84,-4.8,2,V401P +urn:mavedb:00000044-a-1#2827,NA,NA,p.Val71Gln,-3.54,-3.35,1,V401Q +urn:mavedb:00000044-a-1#2828,NA,NA,p.Val71Gln,-3.15,-3.35,2,V401Q +urn:mavedb:00000044-a-1#2829,NA,NA,p.Val71Arg,-4.76,-4.8,1,V401R +urn:mavedb:00000044-a-1#2830,NA,NA,p.Val71Arg,-4.84,-4.8,2,V401R +urn:mavedb:00000044-a-1#2831,NA,NA,p.Val71Ser,-1.91,-1.75,1,V401S +urn:mavedb:00000044-a-1#2832,NA,NA,p.Val71Ser,-1.6,-1.75,2,V401S +urn:mavedb:00000044-a-1#2835,NA,NA,p.Val71Trp,-4.76,-4.69,1,V401W +urn:mavedb:00000044-a-1#2836,NA,NA,p.Val71Trp,-4.61,-4.69,2,V401W +urn:mavedb:00000044-a-1#2837,NA,NA,p.Val71Tyr,-4.76,-4.8,1,V401Y +urn:mavedb:00000044-a-1#2838,NA,NA,p.Val71Tyr,-4.84,-4.8,2,V401Y +urn:mavedb:00000044-a-1#2841,NA,NA,p.Ile72Ala,-0.97,-0.96,1,I402A +urn:mavedb:00000044-a-1#2842,NA,NA,p.Ile72Ala,-0.96,-0.96,2,I402A +urn:mavedb:00000044-a-1#3258,NA,NA,p.Pro82Lys,-1.02,-0.95,2,P412K +urn:mavedb:00000044-a-1#3259,NA,NA,p.Pro82Leu,-1.08,-1.15,1,P412L +urn:mavedb:00000044-a-1#3260,NA,NA,p.Pro82Leu,-1.23,-1.15,2,P412L +urn:mavedb:00000044-a-1#3261,NA,NA,p.Pro82Met,-1.12,-1.32,1,P412M +urn:mavedb:00000044-a-1#3262,NA,NA,p.Pro82Met,-1.52,-1.32,2,P412M +urn:mavedb:00000044-a-1#3263,NA,NA,p.Pro82Asn,-3.58,-3.32,1,P412N +urn:mavedb:00000044-a-1#3264,NA,NA,p.Pro82Asn,-3.06,-3.32,2,P412N +urn:mavedb:00000044-a-1#3265,NA,NA,p.Pro82Gln,-1.76,-1.57,1,P412Q +urn:mavedb:00000044-a-1#3266,NA,NA,p.Pro82Gln,-1.38,-1.57,2,P412Q +urn:mavedb:00000044-a-1#3267,NA,NA,p.Pro82Arg,-1.55,-1.5,1,P412R +urn:mavedb:00000044-a-1#3268,NA,NA,p.Pro82Arg,-1.45,-1.5,2,P412R +urn:mavedb:00000044-a-1#3269,NA,NA,p.Pro82Ser,-1.48,-1.5,1,P412S +urn:mavedb:00000044-a-1#3270,NA,NA,p.Pro82Ser,-1.52,-1.5,2,P412S +urn:mavedb:00000044-a-1#3271,NA,NA,p.Pro82Thr,-0.9,-1.05,1,P412T +urn:mavedb:00000044-a-1#3272,NA,NA,p.Pro82Thr,-1.19,-1.05,2,P412T +urn:mavedb:00000044-a-1#3273,NA,NA,p.Pro82Val,-0.6,-0.66,1,P412V +urn:mavedb:00000044-a-1#3274,NA,NA,p.Pro82Val,-0.71,-0.66,2,P412V +urn:mavedb:00000044-a-1#3275,NA,NA,p.Pro82Trp,-3.94,-4.37,1,P412W +urn:mavedb:00000044-a-1#3276,NA,NA,p.Pro82Trp,-4.79,-4.37,2,P412W +urn:mavedb:00000044-a-1#3277,NA,NA,p.Pro82Tyr,-4.24,-4.47,1,P412Y +urn:mavedb:00000044-a-1#3278,NA,NA,p.Pro82Tyr,-4.7,-4.47,2,P412Y +urn:mavedb:00000044-a-1#3279,NA,NA,p.Pro82*,NA,NA,1,P412 +urn:mavedb:00000044-a-1#3280,NA,NA,p.Pro82*,NA,NA,2,P412 +urn:mavedb:00000044-a-1#3281,NA,NA,p.Gly83Ala,-0.14,-0.16,1,G413A +urn:mavedb:00000044-a-1#3282,NA,NA,p.Gly83Ala,-0.18,-0.16,2,G413A +urn:mavedb:00000044-a-1#3283,NA,NA,p.Gly83Cys,-0.06,-0.06,1,G413C +urn:mavedb:00000044-a-1#3284,NA,NA,p.Gly83Cys,-0.05,-0.06,2,G413C +urn:mavedb:00000044-a-1#3285,NA,NA,p.Gly83Asp,-0.29,-0.3,1,G413D +urn:mavedb:00000044-a-1#3286,NA,NA,p.Gly83Asp,-0.32,-0.3,2,G413D 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+urn:mavedb:00000044-a-1#2852,NA,NA,p.Ile72Gly,-4.84,-4.8,2,I402G +urn:mavedb:00000044-a-1#2853,NA,NA,p.Ile72His,-4.24,-4.42,1,I402H +urn:mavedb:00000044-a-1#2854,NA,NA,p.Ile72His,-4.59,-4.42,2,I402H +urn:mavedb:00000044-a-1#2855,NA,NA,p.Ile72Lys,-4.59,-4.71,1,I402K +urn:mavedb:00000044-a-1#2856,NA,NA,p.Ile72Lys,-4.84,-4.71,2,I402K +urn:mavedb:00000044-a-1#2857,NA,NA,p.Ile72Leu,-0.01,-0.05,1,I402L +urn:mavedb:00000044-a-1#2858,NA,NA,p.Ile72Leu,-0.09,-0.05,2,I402L +urn:mavedb:00000044-a-1#2859,NA,NA,p.Ile72Met,-0.81,-0.91,1,I402M +urn:mavedb:00000044-a-1#2860,NA,NA,p.Ile72Met,-1.01,-0.91,2,I402M +urn:mavedb:00000044-a-1#2861,NA,NA,p.Ile72Asn,-4.54,-4.69,1,I402N +urn:mavedb:00000044-a-1#2862,NA,NA,p.Ile72Asn,-4.84,-4.69,2,I402N +urn:mavedb:00000044-a-1#2863,NA,NA,p.Ile72Pro,-4.61,-4.65,1,I402P +urn:mavedb:00000044-a-1#2864,NA,NA,p.Ile72Pro,-4.69,-4.65,2,I402P +urn:mavedb:00000044-a-1#2865,NA,NA,p.Ile72Gln,-4.37,-4.36,1,I402Q +urn:mavedb:00000044-a-1#2866,NA,NA,p.Ile72Gln,-4.36,-4.36,2,I402Q +urn:mavedb:00000044-a-1#2867,NA,NA,p.Ile72Arg,-2.01,-3.42,1,I402R +urn:mavedb:00000044-a-1#2868,NA,NA,p.Ile72Arg,-4.84,-3.42,2,I402R +urn:mavedb:00000044-a-1#2869,NA,NA,p.Ile72Ser,-2.25,-2.26,1,I402S +urn:mavedb:00000044-a-1#2870,NA,NA,p.Ile72Ser,-2.27,-2.26,2,I402S +urn:mavedb:00000044-a-1#2871,NA,NA,p.Ile72Thr,-0.51,-0.55,1,I402T +urn:mavedb:00000044-a-1#2872,NA,NA,p.Ile72Thr,-0.6,-0.55,2,I402T +urn:mavedb:00000044-a-1#2873,NA,NA,p.Ile72Val,-0.04,0.01,1,I402V +urn:mavedb:00000044-a-1#2874,NA,NA,p.Ile72Val,0.06,0.01,2,I402V +urn:mavedb:00000044-a-1#2875,NA,NA,p.Ile72Trp,-4.28,-2.35,1,I402W +urn:mavedb:00000044-a-1#2876,NA,NA,p.Ile72Trp,-0.42,-2.35,2,I402W +urn:mavedb:00000044-a-1#2877,NA,NA,p.Ile72Tyr,-4.21,-4.53,1,I402Y +urn:mavedb:00000044-a-1#2878,NA,NA,p.Ile72Tyr,-4.84,-4.53,2,I402Y +urn:mavedb:00000044-a-1#2879,NA,NA,p.Ile72*,NA,NA,1,I402 +urn:mavedb:00000044-a-1#2880,NA,NA,p.Ile72*,NA,NA,2,I402 +urn:mavedb:00000044-a-1#2881,NA,NA,p.Arg73Ala,-0.98,-1.06,1,R403A +urn:mavedb:00000044-a-1#2882,NA,NA,p.Arg73Ala,-1.15,-1.06,2,R403A +urn:mavedb:00000044-a-1#2883,NA,NA,p.Arg73Cys,-1.5,-1.51,1,R403C +urn:mavedb:00000044-a-1#2884,NA,NA,p.Arg73Cys,-1.52,-1.51,2,R403C +urn:mavedb:00000044-a-1#2885,NA,NA,p.Arg73Asp,-2.18,-2.21,1,R403D +urn:mavedb:00000044-a-1#2886,NA,NA,p.Arg73Asp,-2.23,-2.21,2,R403D +urn:mavedb:00000044-a-1#2887,NA,NA,p.Arg73Glu,-2.1,-2.11,1,R403E +urn:mavedb:00000044-a-1#2888,NA,NA,p.Arg73Glu,-2.12,-2.11,2,R403E +urn:mavedb:00000044-a-1#2889,NA,NA,p.Arg73Phe,-3.64,-3.49,1,R403F +urn:mavedb:00000044-a-1#2890,NA,NA,p.Arg73Phe,-3.34,-3.49,2,R403F +urn:mavedb:00000044-a-1#2891,NA,NA,p.Arg73Gly,-1.65,-1.7,1,R403G +urn:mavedb:00000044-a-1#2892,NA,NA,p.Arg73Gly,-1.75,-1.7,2,R403G +urn:mavedb:00000044-a-1#2893,NA,NA,p.Arg73His,-1.9,-2.19,1,R403H +urn:mavedb:00000044-a-1#2894,NA,NA,p.Arg73His,-2.48,-2.19,2,R403H +urn:mavedb:00000044-a-1#2895,NA,NA,p.Arg73Ile,-1.65,-1.73,1,R403I +urn:mavedb:00000044-a-1#2896,NA,NA,p.Arg73Ile,-1.82,-1.73,2,R403I +urn:mavedb:00000044-a-1#2897,NA,NA,p.Arg73Lys,-0.06,-0.06,1,R403K +urn:mavedb:00000044-a-1#2898,NA,NA,p.Arg73Lys,-0.07,-0.06,2,R403K +urn:mavedb:00000044-a-1#2899,NA,NA,p.Arg73Leu,-1.22,-1.4,1,R403L +urn:mavedb:00000044-a-1#2900,NA,NA,p.Arg73Leu,-1.57,-1.4,2,R403L +urn:mavedb:00000044-a-1#2901,NA,NA,p.Arg73Met,-0.52,-0.55,1,R403M +urn:mavedb:00000044-a-1#2902,NA,NA,p.Arg73Met,-0.58,-0.55,2,R403M +urn:mavedb:00000044-a-1#2903,NA,NA,p.Arg73Asn,-1.53,-1.47,1,R403N +urn:mavedb:00000044-a-1#2904,NA,NA,p.Arg73Asn,-1.42,-1.47,2,R403N +urn:mavedb:00000044-a-1#2905,NA,NA,p.Arg73Pro,-1.17,-1.25,1,R403P +urn:mavedb:00000044-a-1#2906,NA,NA,p.Arg73Pro,-1.33,-1.25,2,R403P +urn:mavedb:00000044-a-1#2907,NA,NA,p.Arg73Gln,-0.69,-0.72,1,R403Q +urn:mavedb:00000044-a-1#2908,NA,NA,p.Arg73Gln,-0.75,-0.72,2,R403Q +urn:mavedb:00000044-a-1#2909,NA,NA,p.Arg73Ser,-0.8,-0.84,1,R403S +urn:mavedb:00000044-a-1#2910,NA,NA,p.Arg73Ser,-0.89,-0.84,2,R403S +urn:mavedb:00000044-a-1#2911,NA,NA,p.Arg73Thr,-0.67,-0.69,1,R403T +urn:mavedb:00000044-a-1#2912,NA,NA,p.Arg73Thr,-0.71,-0.69,2,R403T +urn:mavedb:00000044-a-1#2913,NA,NA,p.Arg73Val,-1.92,-2.03,1,R403V +urn:mavedb:00000044-a-1#2914,NA,NA,p.Arg73Val,-2.14,-2.03,2,R403V +urn:mavedb:00000044-a-1#2915,NA,NA,p.Arg73Trp,-3.23,-2.82,1,R403W +urn:mavedb:00000044-a-1#2916,NA,NA,p.Arg73Trp,-2.41,-2.82,2,R403W +urn:mavedb:00000044-a-1#2917,NA,NA,p.Arg73Tyr,-2.39,-2.34,1,R403Y +urn:mavedb:00000044-a-1#2918,NA,NA,p.Arg73Tyr,-2.29,-2.34,2,R403Y +urn:mavedb:00000044-a-1#2919,NA,NA,p.Arg73*,NA,NA,1,R403 +urn:mavedb:00000044-a-1#2920,NA,NA,p.Arg73*,NA,NA,2,R403 +urn:mavedb:00000044-a-1#2921,NA,NA,p.Gly74Ala,-0.9,-0.93,1,G404A +urn:mavedb:00000044-a-1#2922,NA,NA,p.Gly74Ala,-0.96,-0.93,2,G404A +urn:mavedb:00000044-a-1#2923,NA,NA,p.Gly74Cys,-1.05,-1.17,1,G404C +urn:mavedb:00000044-a-1#2924,NA,NA,p.Gly74Cys,-1.29,-1.17,2,G404C +urn:mavedb:00000044-a-1#2925,NA,NA,p.Gly74Asp,-2.47,-2.46,1,G404D +urn:mavedb:00000044-a-1#2926,NA,NA,p.Gly74Asp,-2.45,-2.46,2,G404D +urn:mavedb:00000044-a-1#2927,NA,NA,p.Gly74Glu,-1.23,-1.28,1,G404E +urn:mavedb:00000044-a-1#2928,NA,NA,p.Gly74Glu,-1.33,-1.28,2,G404E +urn:mavedb:00000044-a-1#2929,NA,NA,p.Gly74Phe,-2.14,-1.97,1,G404F +urn:mavedb:00000044-a-1#2930,NA,NA,p.Gly74Phe,-1.81,-1.97,2,G404F +urn:mavedb:00000044-a-1#2931,NA,NA,p.Gly74His,-0.78,-0.93,1,G404H +urn:mavedb:00000044-a-1#2932,NA,NA,p.Gly74His,-1.08,-0.93,2,G404H +urn:mavedb:00000044-a-1#2933,NA,NA,p.Gly74Ile,-1.41,-2.78,1,G404I +urn:mavedb:00000044-a-1#2934,NA,NA,p.Gly74Ile,-4.15,-2.78,2,G404I +urn:mavedb:00000044-a-1#2935,NA,NA,p.Gly74Lys,-0.94,-1.02,1,G404K +urn:mavedb:00000044-a-1#3337,NA,NA,p.Gln84Lys,0,-0.04,1,Q414K +urn:mavedb:00000044-a-1#3338,NA,NA,p.Gln84Lys,-0.07,-0.04,2,Q414K +urn:mavedb:00000044-a-1#3339,NA,NA,p.Gln84Leu,-0.25,-0.26,1,Q414L +urn:mavedb:00000044-a-1#3340,NA,NA,p.Gln84Leu,-0.27,-0.26,2,Q414L +urn:mavedb:00000044-a-1#3341,NA,NA,p.Gln84Met,0.06,0.04,1,Q414M +urn:mavedb:00000044-a-1#3342,NA,NA,p.Gln84Met,0.02,0.04,2,Q414M +urn:mavedb:00000044-a-1#3354,NA,NA,p.Gln84Val,-0.06,0.01,2,Q414V +urn:mavedb:00000044-a-1#3373,NA,NA,p.Thr85His,0.1,0.05,1,T415H +urn:mavedb:00000044-a-1#3376,NA,NA,p.Thr85Ile,-0.08,-0.1,2,T415I +urn:mavedb:00000044-a-1#3377,NA,NA,p.Thr85Lys,0,0,1,T415K +urn:mavedb:00000044-a-1#3343,NA,NA,p.Gln84Asn,-0.36,-0.36,1,Q414N +urn:mavedb:00000044-a-1#3344,NA,NA,p.Gln84Asn,-0.35,-0.36,2,Q414N +urn:mavedb:00000044-a-1#3345,NA,NA,p.Gln84Pro,-0.92,-1.01,1,Q414P +urn:mavedb:00000044-a-1#3346,NA,NA,p.Gln84Pro,-1.09,-1.01,2,Q414P +urn:mavedb:00000044-a-1#3347,NA,NA,p.Gln84Arg,-0.06,-0.04,1,Q414R +urn:mavedb:00000044-a-1#3348,NA,NA,p.Gln84Arg,-0.03,-0.04,2,Q414R +urn:mavedb:00000044-a-1#3349,NA,NA,p.Gln84Ser,0.02,0,1,Q414S +urn:mavedb:00000044-a-1#3350,NA,NA,p.Gln84Ser,-0.01,0,2,Q414S +urn:mavedb:00000044-a-1#3351,NA,NA,p.Gln84Thr,0,0.01,1,Q414T 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+urn:mavedb:00000044-a-1#3438,NA,NA,p.Gly86Tyr,-2.86,-2.74,2,G416Y +urn:mavedb:00000044-a-1#3439,NA,NA,p.Gly86*,NA,NA,1,G416 +urn:mavedb:00000044-a-1#3440,NA,NA,p.Gly86*,NA,NA,2,G416 +urn:mavedb:00000044-a-1#3441,NA,NA,p.Lys87Ala,-0.31,-0.35,1,K417A +urn:mavedb:00000044-a-1#3442,NA,NA,p.Lys87Ala,-0.4,-0.35,2,K417A +urn:mavedb:00000044-a-1#3443,NA,NA,p.Lys87Cys,-0.46,-0.42,1,K417C +urn:mavedb:00000044-a-1#3444,NA,NA,p.Lys87Cys,-0.38,-0.42,2,K417C +urn:mavedb:00000044-a-1#3445,NA,NA,p.Lys87Asp,-0.96,-1.04,1,K417D +urn:mavedb:00000044-a-1#3446,NA,NA,p.Lys87Asp,-1.11,-1.04,2,K417D +urn:mavedb:00000044-a-1#3447,NA,NA,p.Lys87Glu,-0.66,-0.75,1,K417E +urn:mavedb:00000044-a-1#3448,NA,NA,p.Lys87Glu,-0.84,-0.75,2,K417E +urn:mavedb:00000044-a-1#3449,NA,NA,p.Lys87Phe,-0.12,-0.13,1,K417F +urn:mavedb:00000044-a-1#3450,NA,NA,p.Lys87Phe,-0.15,-0.13,2,K417F +urn:mavedb:00000044-a-1#3519,NA,NA,p.Ile88*,NA,NA,1,I418 +urn:mavedb:00000044-a-1#3520,NA,NA,p.Ile88*,NA,NA,2,I418 +urn:mavedb:00000044-a-1#3456,NA,NA,p.Lys87Ile,-0.36,-0.34,2,K417I +urn:mavedb:00000044-a-1#3451,NA,NA,p.Lys87Gly,-0.48,-0.51,1,K417G +urn:mavedb:00000044-a-1#3452,NA,NA,p.Lys87Gly,-0.53,-0.51,2,K417G +urn:mavedb:00000044-a-1#3453,NA,NA,p.Lys87His,-0.16,-0.17,1,K417H +urn:mavedb:00000044-a-1#3454,NA,NA,p.Lys87His,-0.18,-0.17,2,K417H +urn:mavedb:00000044-a-1#3455,NA,NA,p.Lys87Ile,-0.32,-0.34,1,K417I +urn:mavedb:00000044-a-1#3457,NA,NA,p.Lys87Leu,-0.3,-0.31,1,K417L +urn:mavedb:00000044-a-1#3458,NA,NA,p.Lys87Leu,-0.32,-0.31,2,K417L +urn:mavedb:00000044-a-1#3459,NA,NA,p.Lys87Met,-0.35,-0.39,1,K417M +urn:mavedb:00000044-a-1#3460,NA,NA,p.Lys87Met,-0.42,-0.39,2,K417M +urn:mavedb:00000044-a-1#3461,NA,NA,p.Lys87Asn,-0.43,-0.45,1,K417N +urn:mavedb:00000044-a-1#3462,NA,NA,p.Lys87Asn,-0.48,-0.45,2,K417N +urn:mavedb:00000044-a-1#3463,NA,NA,p.Lys87Pro,-0.26,-0.35,1,K417P +urn:mavedb:00000044-a-1#3464,NA,NA,p.Lys87Pro,-0.44,-0.35,2,K417P +urn:mavedb:00000044-a-1#3465,NA,NA,p.Lys87Gln,-0.63,-0.62,1,K417Q +urn:mavedb:00000044-a-1#3466,NA,NA,p.Lys87Gln,-0.62,-0.62,2,K417Q +urn:mavedb:00000044-a-1#3467,NA,NA,p.Lys87Arg,-0.18,-0.17,1,K417R +urn:mavedb:00000044-a-1#3468,NA,NA,p.Lys87Arg,-0.15,-0.17,2,K417R +urn:mavedb:00000044-a-1#3469,NA,NA,p.Lys87Ser,-0.43,-0.46,1,K417S +urn:mavedb:00000044-a-1#3470,NA,NA,p.Lys87Ser,-0.49,-0.46,2,K417S +urn:mavedb:00000044-a-1#3471,NA,NA,p.Lys87Thr,-0.23,-0.26,1,K417T +urn:mavedb:00000044-a-1#3472,NA,NA,p.Lys87Thr,-0.29,-0.26,2,K417T +urn:mavedb:00000044-a-1#3473,NA,NA,p.Lys87Val,-0.25,-0.32,1,K417V +urn:mavedb:00000044-a-1#3474,NA,NA,p.Lys87Val,-0.39,-0.32,2,K417V +urn:mavedb:00000044-a-1#3475,NA,NA,p.Lys87Trp,-0.25,-0.31,1,K417W +urn:mavedb:00000044-a-1#3476,NA,NA,p.Lys87Trp,-0.38,-0.31,2,K417W +urn:mavedb:00000044-a-1#3477,NA,NA,p.Lys87Tyr,-0.07,-0.08,1,K417Y +urn:mavedb:00000044-a-1#3478,NA,NA,p.Lys87Tyr,-0.09,-0.08,2,K417Y +urn:mavedb:00000044-a-1#3479,NA,NA,p.Lys87*,NA,NA,1,K417 +urn:mavedb:00000044-a-1#3480,NA,NA,p.Lys87*,NA,NA,2,K417 +urn:mavedb:00000044-a-1#3481,NA,NA,p.Ile88Ala,-1.58,-1.46,1,I418A +urn:mavedb:00000044-a-1#3482,NA,NA,p.Ile88Ala,-1.33,-1.46,2,I418A +urn:mavedb:00000044-a-1#3483,NA,NA,p.Ile88Cys,-0.88,-1.05,1,I418C +urn:mavedb:00000044-a-1#3484,NA,NA,p.Ile88Cys,-1.21,-1.05,2,I418C +urn:mavedb:00000044-a-1#3485,NA,NA,p.Ile88Asp,-4.76,-4.8,1,I418D +urn:mavedb:00000044-a-1#3486,NA,NA,p.Ile88Asp,-4.84,-4.8,2,I418D +urn:mavedb:00000044-a-1#3487,NA,NA,p.Ile88Glu,-4.76,-4.8,1,I418E +urn:mavedb:00000044-a-1#3488,NA,NA,p.Ile88Glu,-4.84,-4.8,2,I418E +urn:mavedb:00000044-a-1#3489,NA,NA,p.Ile88Phe,-2.7,-2.66,1,I418F +urn:mavedb:00000044-a-1#3490,NA,NA,p.Ile88Phe,-2.62,-2.66,2,I418F +urn:mavedb:00000044-a-1#3491,NA,NA,p.Ile88Gly,-4.75,-4.55,1,I418G +urn:mavedb:00000044-a-1#3492,NA,NA,p.Ile88Gly,-4.35,-4.55,2,I418G +urn:mavedb:00000044-a-1#3493,NA,NA,p.Ile88His,-4.69,-4.76,1,I418H +urn:mavedb:00000044-a-1#3494,NA,NA,p.Ile88His,-4.84,-4.76,2,I418H +urn:mavedb:00000044-a-1#3495,NA,NA,p.Ile88Lys,-4.47,-4.64,1,I418K +urn:mavedb:00000044-a-1#3496,NA,NA,p.Ile88Lys,-4.81,-4.64,2,I418K +urn:mavedb:00000044-a-1#3497,NA,NA,p.Ile88Leu,-0.63,-0.73,1,I418L +urn:mavedb:00000044-a-1#3498,NA,NA,p.Ile88Leu,-0.82,-0.73,2,I418L +urn:mavedb:00000044-a-1#3499,NA,NA,p.Ile88Met,-0.71,-0.76,1,I418M +urn:mavedb:00000044-a-1#3500,NA,NA,p.Ile88Met,-0.8,-0.76,2,I418M +urn:mavedb:00000044-a-1#3501,NA,NA,p.Ile88Asn,-4.74,-4.79,1,I418N +urn:mavedb:00000044-a-1#3502,NA,NA,p.Ile88Asn,-4.84,-4.79,2,I418N +urn:mavedb:00000044-a-1#3503,NA,NA,p.Ile88Pro,-4.62,-4.73,1,I418P +urn:mavedb:00000044-a-1#3504,NA,NA,p.Ile88Pro,-4.84,-4.73,2,I418P +urn:mavedb:00000044-a-1#3505,NA,NA,p.Ile88Gln,-1.75,-1.82,1,I418Q +urn:mavedb:00000044-a-1#3506,NA,NA,p.Ile88Gln,-1.9,-1.82,2,I418Q +urn:mavedb:00000044-a-1#3507,NA,NA,p.Ile88Arg,-4.74,-4.76,1,I418R +urn:mavedb:00000044-a-1#3508,NA,NA,p.Ile88Arg,-4.77,-4.76,2,I418R +urn:mavedb:00000044-a-1#3509,NA,NA,p.Ile88Ser,-3.33,-3.48,1,I418S +urn:mavedb:00000044-a-1#3510,NA,NA,p.Ile88Ser,-3.64,-3.48,2,I418S +urn:mavedb:00000044-a-1#3511,NA,NA,p.Ile88Thr,-0.68,-0.85,1,I418T +urn:mavedb:00000044-a-1#3512,NA,NA,p.Ile88Thr,-1.01,-0.85,2,I418T +urn:mavedb:00000044-a-1#3513,NA,NA,p.Ile88Val,-0.13,-0.17,1,I418V +urn:mavedb:00000044-a-1#3514,NA,NA,p.Ile88Val,-0.22,-0.17,2,I418V +urn:mavedb:00000044-a-1#3515,NA,NA,p.Ile88Trp,-4.71,-4.44,1,I418W +urn:mavedb:00000044-a-1#3516,NA,NA,p.Ile88Trp,-4.17,-4.44,2,I418W +urn:mavedb:00000044-a-1#3517,NA,NA,p.Ile88Tyr,-4.41,-4.57,1,I418Y +urn:mavedb:00000044-a-1#3518,NA,NA,p.Ile88Tyr,-4.73,-4.57,2,I418Y +urn:mavedb:00000044-a-1#3521,NA,NA,p.Ala89Cys,-0.26,-0.27,1,A419C +urn:mavedb:00000044-a-1#3522,NA,NA,p.Ala89Cys,-0.28,-0.27,2,A419C +urn:mavedb:00000044-a-1#3523,NA,NA,p.Ala89Asp,-3.12,-3.23,1,A419D +urn:mavedb:00000044-a-1#3524,NA,NA,p.Ala89Asp,-3.34,-3.23,2,A419D +urn:mavedb:00000044-a-1#3525,NA,NA,p.Ala89Glu,-3.93,-3.75,1,A419E +urn:mavedb:00000044-a-1#3526,NA,NA,p.Ala89Glu,-3.58,-3.75,2,A419E +urn:mavedb:00000044-a-1#3527,NA,NA,p.Ala89Phe,-0.96,-1.07,1,A419F +urn:mavedb:00000044-a-1#3528,NA,NA,p.Ala89Phe,-1.19,-1.07,2,A419F +urn:mavedb:00000044-a-1#3529,NA,NA,p.Ala89Gly,-0.72,-0.8,1,A419G +urn:mavedb:00000044-a-1#3530,NA,NA,p.Ala89Gly,-0.88,-0.8,2,A419G +urn:mavedb:00000044-a-1#3531,NA,NA,p.Ala89His,-0.73,-0.77,1,A419H +urn:mavedb:00000044-a-1#3532,NA,NA,p.Ala89His,-0.81,-0.77,2,A419H +urn:mavedb:00000044-a-1#3533,NA,NA,p.Ala89Ile,-0.66,-0.73,1,A419I +urn:mavedb:00000044-a-1#3534,NA,NA,p.Ala89Ile,-0.8,-0.73,2,A419I +urn:mavedb:00000044-a-1#3535,NA,NA,p.Ala89Lys,-1.75,-2.04,1,A419K +urn:mavedb:00000044-a-1#3536,NA,NA,p.Ala89Lys,-2.32,-2.04,2,A419K +urn:mavedb:00000044-a-1#3537,NA,NA,p.Ala89Leu,-2.21,-2.28,1,A419L +urn:mavedb:00000044-a-1#3538,NA,NA,p.Ala89Leu,-2.34,-2.28,2,A419L +urn:mavedb:00000044-a-1#3539,NA,NA,p.Ala89Met,-0.99,-1.11,1,A419M +urn:mavedb:00000044-a-1#3540,NA,NA,p.Ala89Met,-1.23,-1.11,2,A419M +urn:mavedb:00000044-a-1#3541,NA,NA,p.Ala89Asn,-0.86,-0.91,1,A419N +urn:mavedb:00000044-a-1#3542,NA,NA,p.Ala89Asn,-0.95,-0.91,2,A419N +urn:mavedb:00000044-a-1#3543,NA,NA,p.Ala89Pro,-0.2,-0.22,1,A419P +urn:mavedb:00000044-a-1#3544,NA,NA,p.Ala89Pro,-0.24,-0.22,2,A419P +urn:mavedb:00000044-a-1#3545,NA,NA,p.Ala89Gln,-1.03,-1.15,1,A419Q +urn:mavedb:00000044-a-1#3546,NA,NA,p.Ala89Gln,-1.27,-1.15,2,A419Q +urn:mavedb:00000044-a-1#3547,NA,NA,p.Ala89Arg,-1.09,-1.14,1,A419R +urn:mavedb:00000044-a-1#3548,NA,NA,p.Ala89Arg,-1.19,-1.14,2,A419R +urn:mavedb:00000044-a-1#3549,NA,NA,p.Ala89Ser,-0.11,-0.1,1,A419S +urn:mavedb:00000044-a-1#3550,NA,NA,p.Ala89Ser,-0.1,-0.1,2,A419S +urn:mavedb:00000044-a-1#3551,NA,NA,p.Ala89Thr,-0.19,-0.23,1,A419T +urn:mavedb:00000044-a-1#3552,NA,NA,p.Ala89Thr,-0.27,-0.23,2,A419T +urn:mavedb:00000044-a-1#3553,NA,NA,p.Ala89Val,-0.44,-0.49,1,A419V +urn:mavedb:00000044-a-1#3554,NA,NA,p.Ala89Val,-0.55,-0.49,2,A419V +urn:mavedb:00000044-a-1#3555,NA,NA,p.Ala89Trp,-2.79,-2.69,1,A419W +urn:mavedb:00000044-a-1#3556,NA,NA,p.Ala89Trp,-2.59,-2.69,2,A419W +urn:mavedb:00000044-a-1#3557,NA,NA,p.Ala89Tyr,-0.79,-0.86,1,A419Y +urn:mavedb:00000044-a-1#3558,NA,NA,p.Ala89Tyr,-0.94,-0.86,2,A419Y +urn:mavedb:00000044-a-1#3559,NA,NA,p.Ala89*,NA,NA,1,A419 +urn:mavedb:00000044-a-1#3560,NA,NA,p.Ala89*,NA,NA,2,A419 +urn:mavedb:00000044-a-1#3561,NA,NA,p.Asp90Ala,-0.09,-0.11,1,D420A +urn:mavedb:00000044-a-1#3562,NA,NA,p.Asp90Ala,-0.12,-0.11,2,D420A +urn:mavedb:00000044-a-1#3563,NA,NA,p.Asp90Cys,-0.25,-0.27,1,D420C +urn:mavedb:00000044-a-1#3564,NA,NA,p.Asp90Cys,-0.29,-0.27,2,D420C +urn:mavedb:00000044-a-1#3565,NA,NA,p.Asp90Glu,-0.12,-0.13,1,D420E +urn:mavedb:00000044-a-1#3566,NA,NA,p.Asp90Glu,-0.15,-0.13,2,D420E +urn:mavedb:00000044-a-1#3567,NA,NA,p.Asp90Phe,-0.29,-0.32,1,D420F +urn:mavedb:00000044-a-1#3568,NA,NA,p.Asp90Phe,-0.36,-0.32,2,D420F +urn:mavedb:00000044-a-1#3569,NA,NA,p.Asp90Gly,-0.52,-0.56,1,D420G +urn:mavedb:00000044-a-1#3570,NA,NA,p.Asp90Gly,-0.61,-0.56,2,D420G +urn:mavedb:00000044-a-1#3571,NA,NA,p.Asp90His,-0.29,-0.29,1,D420H +urn:mavedb:00000044-a-1#3572,NA,NA,p.Asp90His,-0.29,-0.29,2,D420H +urn:mavedb:00000044-a-1#3573,NA,NA,p.Asp90Ile,-0.62,-0.66,1,D420I +urn:mavedb:00000044-a-1#3574,NA,NA,p.Asp90Ile,-0.7,-0.66,2,D420I +urn:mavedb:00000044-a-1#3575,NA,NA,p.Asp90Lys,-0.08,-0.05,1,D420K +urn:mavedb:00000044-a-1#3576,NA,NA,p.Asp90Lys,-0.02,-0.05,2,D420K +urn:mavedb:00000044-a-1#3577,NA,NA,p.Asp90Leu,-0.16,-0.18,1,D420L +urn:mavedb:00000044-a-1#3578,NA,NA,p.Asp90Leu,-0.19,-0.18,2,D420L +urn:mavedb:00000044-a-1#3579,NA,NA,p.Asp90Met,-0.14,-0.14,1,D420M +urn:mavedb:00000044-a-1#3580,NA,NA,p.Asp90Met,-0.14,-0.14,2,D420M +urn:mavedb:00000044-a-1#3581,NA,NA,p.Asp90Asn,-0.02,-0.02,1,D420N +urn:mavedb:00000044-a-1#3582,NA,NA,p.Asp90Asn,-0.02,-0.02,2,D420N +urn:mavedb:00000044-a-1#3583,NA,NA,p.Asp90Pro,-4.68,-4.55,1,D420P +urn:mavedb:00000044-a-1#3584,NA,NA,p.Asp90Pro,-4.43,-4.55,2,D420P +urn:mavedb:00000044-a-1#3585,NA,NA,p.Asp90Gln,-0.04,-0.01,1,D420Q +urn:mavedb:00000044-a-1#3586,NA,NA,p.Asp90Gln,0.02,-0.01,2,D420Q +urn:mavedb:00000044-a-1#3587,NA,NA,p.Asp90Arg,-0.04,-0.05,1,D420R +urn:mavedb:00000044-a-1#3588,NA,NA,p.Asp90Arg,-0.06,-0.05,2,D420R +urn:mavedb:00000044-a-1#3589,NA,NA,p.Asp90Ser,-0.14,-0.11,1,D420S +urn:mavedb:00000044-a-1#3590,NA,NA,p.Asp90Ser,-0.08,-0.11,2,D420S +urn:mavedb:00000044-a-1#3623,NA,NA,p.Tyr91Asn,-0.16,-0.18,1,Y421N +urn:mavedb:00000044-a-1#3624,NA,NA,p.Tyr91Asn,-0.2,-0.18,2,Y421N +urn:mavedb:00000044-a-1#3591,NA,NA,p.Asp90Thr,-0.25,-0.26,1,D420T +urn:mavedb:00000044-a-1#3592,NA,NA,p.Asp90Thr,-0.27,-0.26,2,D420T +urn:mavedb:00000044-a-1#3593,NA,NA,p.Asp90Val,-0.61,-0.67,1,D420V +urn:mavedb:00000044-a-1#3594,NA,NA,p.Asp90Val,-0.74,-0.67,2,D420V +urn:mavedb:00000044-a-1#3595,NA,NA,p.Asp90Trp,-0.29,-0.3,1,D420W +urn:mavedb:00000044-a-1#3596,NA,NA,p.Asp90Trp,-0.31,-0.3,2,D420W +urn:mavedb:00000044-a-1#3597,NA,NA,p.Asp90Tyr,-0.28,-0.3,1,D420Y +urn:mavedb:00000044-a-1#3598,NA,NA,p.Asp90Tyr,-0.32,-0.3,2,D420Y +urn:mavedb:00000044-a-1#3599,NA,NA,p.Asp90*,NA,NA,1,D420 +urn:mavedb:00000044-a-1#3600,NA,NA,p.Asp90*,NA,NA,2,D420 +urn:mavedb:00000044-a-1#3601,NA,NA,p.Tyr91Ala,-0.69,-0.68,1,Y421A +urn:mavedb:00000044-a-1#3602,NA,NA,p.Tyr91Ala,-0.67,-0.68,2,Y421A +urn:mavedb:00000044-a-1#3603,NA,NA,p.Tyr91Cys,-0.38,-0.43,1,Y421C +urn:mavedb:00000044-a-1#3604,NA,NA,p.Tyr91Cys,-0.49,-0.43,2,Y421C +urn:mavedb:00000044-a-1#3605,NA,NA,p.Tyr91Asp,-1.52,-1.72,1,Y421D +urn:mavedb:00000044-a-1#3606,NA,NA,p.Tyr91Asp,-1.92,-1.72,2,Y421D +urn:mavedb:00000044-a-1#3607,NA,NA,p.Tyr91Glu,-2.01,-2.08,1,Y421E +urn:mavedb:00000044-a-1#3608,NA,NA,p.Tyr91Glu,-2.14,-2.08,2,Y421E +urn:mavedb:00000044-a-1#3609,NA,NA,p.Tyr91Phe,-0.03,-0.02,1,Y421F +urn:mavedb:00000044-a-1#3610,NA,NA,p.Tyr91Phe,-0.02,-0.02,2,Y421F +urn:mavedb:00000044-a-1#3611,NA,NA,p.Tyr91Gly,-0.72,-0.72,1,Y421G +urn:mavedb:00000044-a-1#3612,NA,NA,p.Tyr91Gly,-0.72,-0.72,2,Y421G +urn:mavedb:00000044-a-1#3613,NA,NA,p.Tyr91His,-0.67,-0.6,1,Y421H +urn:mavedb:00000044-a-1#3614,NA,NA,p.Tyr91His,-0.54,-0.6,2,Y421H +urn:mavedb:00000044-a-1#3615,NA,NA,p.Tyr91Ile,-0.46,-0.47,1,Y421I +urn:mavedb:00000044-a-1#3616,NA,NA,p.Tyr91Ile,-0.47,-0.47,2,Y421I +urn:mavedb:00000044-a-1#3617,NA,NA,p.Tyr91Lys,-0.53,-0.52,1,Y421K +urn:mavedb:00000044-a-1#3618,NA,NA,p.Tyr91Lys,-0.51,-0.52,2,Y421K +urn:mavedb:00000044-a-1#3619,NA,NA,p.Tyr91Leu,-0.11,-0.14,1,Y421L +urn:mavedb:00000044-a-1#3620,NA,NA,p.Tyr91Leu,-0.17,-0.14,2,Y421L +urn:mavedb:00000044-a-1#3621,NA,NA,p.Tyr91Met,-0.34,-0.39,1,Y421M +urn:mavedb:00000044-a-1#3622,NA,NA,p.Tyr91Met,-0.44,-0.39,2,Y421M +urn:mavedb:00000044-a-1#3625,NA,NA,p.Tyr91Pro,-4.69,-4.76,1,Y421P +urn:mavedb:00000044-a-1#3626,NA,NA,p.Tyr91Pro,-4.84,-4.76,2,Y421P +urn:mavedb:00000044-a-1#3627,NA,NA,p.Tyr91Gln,-0.74,-0.76,1,Y421Q +urn:mavedb:00000044-a-1#3628,NA,NA,p.Tyr91Gln,-0.77,-0.76,2,Y421Q +urn:mavedb:00000044-a-1#3629,NA,NA,p.Tyr91Arg,-0.62,-0.63,1,Y421R +urn:mavedb:00000044-a-1#3630,NA,NA,p.Tyr91Arg,-0.64,-0.63,2,Y421R +urn:mavedb:00000044-a-1#3631,NA,NA,p.Tyr91Ser,-0.72,-0.76,1,Y421S +urn:mavedb:00000044-a-1#3632,NA,NA,p.Tyr91Ser,-0.8,-0.76,2,Y421S +urn:mavedb:00000044-a-1#3633,NA,NA,p.Tyr91Thr,-1.16,-1.18,1,Y421T +urn:mavedb:00000044-a-1#3634,NA,NA,p.Tyr91Thr,-1.2,-1.18,2,Y421T +urn:mavedb:00000044-a-1#3635,NA,NA,p.Tyr91Val,-0.59,-0.63,1,Y421V +urn:mavedb:00000044-a-1#3636,NA,NA,p.Tyr91Val,-0.67,-0.63,2,Y421V +urn:mavedb:00000044-a-1#3637,NA,NA,p.Tyr91Trp,-0.54,-0.61,1,Y421W +urn:mavedb:00000044-a-1#3638,NA,NA,p.Tyr91Trp,-0.68,-0.61,2,Y421W +urn:mavedb:00000044-a-1#3639,NA,NA,p.Tyr91*,NA,NA,1,Y421 +urn:mavedb:00000044-a-1#3640,NA,NA,p.Tyr91*,NA,NA,2,Y421 +urn:mavedb:00000044-a-1#3641,NA,NA,p.Asn92Ala,-1.19,-1.36,1,N422A +urn:mavedb:00000044-a-1#3642,NA,NA,p.Asn92Ala,-1.52,-1.36,2,N422A +urn:mavedb:00000044-a-1#3643,NA,NA,p.Asn92Cys,-1.87,-2.45,1,N422C +urn:mavedb:00000044-a-1#3644,NA,NA,p.Asn92Cys,-3.03,-2.45,2,N422C +urn:mavedb:00000044-a-1#3645,NA,NA,p.Asn92Asp,-2.44,-2.64,1,N422D +urn:mavedb:00000044-a-1#3646,NA,NA,p.Asn92Asp,-2.83,-2.64,2,N422D +urn:mavedb:00000044-a-1#3647,NA,NA,p.Asn92Glu,-4.76,-4.8,1,N422E +urn:mavedb:00000044-a-1#3648,NA,NA,p.Asn92Glu,-4.84,-4.8,2,N422E +urn:mavedb:00000044-a-1#3649,NA,NA,p.Asn92Phe,-4.76,-4.8,1,N422F +urn:mavedb:00000044-a-1#3650,NA,NA,p.Asn92Phe,-4.84,-4.8,2,N422F +urn:mavedb:00000044-a-1#3651,NA,NA,p.Asn92Gly,-3.41,-2.48,1,N422G +urn:mavedb:00000044-a-1#3652,NA,NA,p.Asn92Gly,-1.56,-2.48,2,N422G +urn:mavedb:00000044-a-1#3653,NA,NA,p.Asn92His,-4.76,-4.8,1,N422H +urn:mavedb:00000044-a-1#3654,NA,NA,p.Asn92His,-4.84,-4.8,2,N422H +urn:mavedb:00000044-a-1#3655,NA,NA,p.Asn92Ile,-4.7,-4.77,1,N422I +urn:mavedb:00000044-a-1#3656,NA,NA,p.Asn92Ile,-4.84,-4.77,2,N422I +urn:mavedb:00000044-a-1#3657,NA,NA,p.Asn92Lys,-4.63,-4.73,1,N422K +urn:mavedb:00000044-a-1#3658,NA,NA,p.Asn92Lys,-4.84,-4.73,2,N422K +urn:mavedb:00000044-a-1#3659,NA,NA,p.Asn92Leu,-4.75,-4.8,1,N422L +urn:mavedb:00000044-a-1#3660,NA,NA,p.Asn92Leu,-4.84,-4.8,2,N422L +urn:mavedb:00000044-a-1#3661,NA,NA,p.Asn92Met,-4.76,-4.34,1,N422M +urn:mavedb:00000044-a-1#3662,NA,NA,p.Asn92Met,-3.92,-4.34,2,N422M +urn:mavedb:00000044-a-1#3663,NA,NA,p.Asn92Pro,-4.35,-4.59,1,N422P +urn:mavedb:00000044-a-1#3664,NA,NA,p.Asn92Pro,-4.84,-4.59,2,N422P +urn:mavedb:00000044-a-1#3665,NA,NA,p.Asn92Gln,-3.46,-3.9,1,N422Q +urn:mavedb:00000044-a-1#3666,NA,NA,p.Asn92Gln,-4.35,-3.9,2,N422Q +urn:mavedb:00000044-a-1#3667,NA,NA,p.Asn92Arg,-4.76,-4.77,1,N422R +urn:mavedb:00000044-a-1#3668,NA,NA,p.Asn92Arg,-4.79,-4.77,2,N422R +urn:mavedb:00000044-a-1#3669,NA,NA,p.Asn92Ser,-0.74,-0.75,1,N422S +urn:mavedb:00000044-a-1#3670,NA,NA,p.Asn92Ser,-0.77,-0.75,2,N422S +urn:mavedb:00000044-a-1#3671,NA,NA,p.Asn92Thr,-4.43,-4.53,1,N422T +urn:mavedb:00000044-a-1#3672,NA,NA,p.Asn92Thr,-4.63,-4.53,2,N422T +urn:mavedb:00000044-a-1#3673,NA,NA,p.Asn92Val,-4.76,-4.8,1,N422V +urn:mavedb:00000044-a-1#3674,NA,NA,p.Asn92Val,-4.83,-4.8,2,N422V +urn:mavedb:00000044-a-1#3675,NA,NA,p.Asn92Trp,-4.76,-4.8,1,N422W +urn:mavedb:00000044-a-1#3676,NA,NA,p.Asn92Trp,-4.84,-4.8,2,N422W +urn:mavedb:00000044-a-1#3677,NA,NA,p.Asn92Tyr,-4.76,-4.62,1,N422Y +urn:mavedb:00000044-a-1#3678,NA,NA,p.Asn92Tyr,-4.49,-4.62,2,N422Y +urn:mavedb:00000044-a-1#3679,NA,NA,p.Asn92*,NA,NA,1,N422 +urn:mavedb:00000044-a-1#3680,NA,NA,p.Asn92*,NA,NA,2,N422 +urn:mavedb:00000044-a-1#3681,NA,NA,p.Tyr93Ala,-4.76,-4.8,1,Y423A +urn:mavedb:00000044-a-1#3682,NA,NA,p.Tyr93Ala,-4.84,-4.8,2,Y423A +urn:mavedb:00000044-a-1#3683,NA,NA,p.Tyr93Cys,-4.59,-4.57,1,Y423C +urn:mavedb:00000044-a-1#3684,NA,NA,p.Tyr93Cys,-4.55,-4.57,2,Y423C +urn:mavedb:00000044-a-1#3685,NA,NA,p.Tyr93Asp,-4.57,-4.7,1,Y423D +urn:mavedb:00000044-a-1#3686,NA,NA,p.Tyr93Asp,-4.84,-4.7,2,Y423D +urn:mavedb:00000044-a-1#3687,NA,NA,p.Tyr93Glu,-4.67,-4.53,1,Y423E +urn:mavedb:00000044-a-1#3688,NA,NA,p.Tyr93Glu,-4.38,-4.53,2,Y423E +urn:mavedb:00000044-a-1#3689,NA,NA,p.Tyr93Phe,-0.56,-0.58,1,Y423F +urn:mavedb:00000044-a-1#3690,NA,NA,p.Tyr93Phe,-0.59,-0.58,2,Y423F +urn:mavedb:00000044-a-1#3691,NA,NA,p.Tyr93Gly,-4.59,-4.72,1,Y423G +urn:mavedb:00000044-a-1#3692,NA,NA,p.Tyr93Gly,-4.84,-4.72,2,Y423G +urn:mavedb:00000044-a-1#3693,NA,NA,p.Tyr93His,-4.37,-4.26,1,Y423H +urn:mavedb:00000044-a-1#3694,NA,NA,p.Tyr93His,-4.14,-4.26,2,Y423H +urn:mavedb:00000044-a-1#3695,NA,NA,p.Tyr93Ile,-2.16,-2.16,1,Y423I +urn:mavedb:00000044-a-1#3696,NA,NA,p.Tyr93Ile,-2.16,-2.16,2,Y423I +urn:mavedb:00000044-a-1#3697,NA,NA,p.Tyr93Lys,-4.55,-4.7,1,Y423K +urn:mavedb:00000044-a-1#3698,NA,NA,p.Tyr93Lys,-4.84,-4.7,2,Y423K +urn:mavedb:00000044-a-1#3699,NA,NA,p.Tyr93Leu,-2.66,-3.11,1,Y423L +urn:mavedb:00000044-a-1#3700,NA,NA,p.Tyr93Leu,-3.55,-3.11,2,Y423L +urn:mavedb:00000044-a-1#3712,NA,NA,p.Tyr93Ser,-4.84,-4.79,2,Y423S +urn:mavedb:00000044-a-1#3701,NA,NA,p.Tyr93Met,-2.84,-2.77,1,Y423M +urn:mavedb:00000044-a-1#3702,NA,NA,p.Tyr93Met,-2.71,-2.77,2,Y423M +urn:mavedb:00000044-a-1#3703,NA,NA,p.Tyr93Asn,-4.7,-4.77,1,Y423N +urn:mavedb:00000044-a-1#3704,NA,NA,p.Tyr93Asn,-4.84,-4.77,2,Y423N +urn:mavedb:00000044-a-1#3705,NA,NA,p.Tyr93Pro,-4.72,-4.78,1,Y423P +urn:mavedb:00000044-a-1#3706,NA,NA,p.Tyr93Pro,-4.84,-4.78,2,Y423P +urn:mavedb:00000044-a-1#3707,NA,NA,p.Tyr93Gln,-4.76,-4.44,1,Y423Q +urn:mavedb:00000044-a-1#3708,NA,NA,p.Tyr93Gln,-4.13,-4.44,2,Y423Q +urn:mavedb:00000044-a-1#3709,NA,NA,p.Tyr93Arg,-4.76,-4.79,1,Y423R +urn:mavedb:00000044-a-1#3710,NA,NA,p.Tyr93Arg,-4.81,-4.79,2,Y423R +urn:mavedb:00000044-a-1#3711,NA,NA,p.Tyr93Ser,-4.73,-4.79,1,Y423S +urn:mavedb:00000044-a-1#3713,NA,NA,p.Tyr93Thr,-4.76,-4.75,1,Y423T +urn:mavedb:00000044-a-1#3714,NA,NA,p.Tyr93Thr,-4.75,-4.75,2,Y423T +urn:mavedb:00000044-a-1#3715,NA,NA,p.Tyr93Val,-4.02,-4.43,1,Y423V +urn:mavedb:00000044-a-1#3716,NA,NA,p.Tyr93Val,-4.84,-4.43,2,Y423V +urn:mavedb:00000044-a-1#3717,NA,NA,p.Tyr93Trp,-4.69,-4.52,1,Y423W +urn:mavedb:00000044-a-1#3718,NA,NA,p.Tyr93Trp,-4.35,-4.52,2,Y423W +urn:mavedb:00000044-a-1#3719,NA,NA,p.Tyr93*,NA,NA,1,Y423 +urn:mavedb:00000044-a-1#3720,NA,NA,p.Tyr93*,NA,NA,2,Y423 +urn:mavedb:00000044-a-1#3721,NA,NA,p.Lys94Ala,-0.2,-0.21,1,K424A +urn:mavedb:00000044-a-1#3722,NA,NA,p.Lys94Ala,-0.22,-0.21,2,K424A +urn:mavedb:00000044-a-1#3723,NA,NA,p.Lys94Cys,-0.54,-0.52,1,K424C +urn:mavedb:00000044-a-1#3724,NA,NA,p.Lys94Cys,-0.51,-0.52,2,K424C +urn:mavedb:00000044-a-1#3725,NA,NA,p.Lys94Asp,-1.75,-1.75,1,K424D +urn:mavedb:00000044-a-1#3726,NA,NA,p.Lys94Asp,-1.74,-1.75,2,K424D +urn:mavedb:00000044-a-1#3727,NA,NA,p.Lys94Glu,-2.57,-2.56,1,K424E +urn:mavedb:00000044-a-1#2943,NA,NA,p.Gly74Pro,-4.76,-4.8,1,G404P +urn:mavedb:00000044-a-1#2944,NA,NA,p.Gly74Pro,-4.84,-4.8,2,G404P +urn:mavedb:00000044-a-1#2945,NA,NA,p.Gly74Gln,-1.06,-1.02,1,G404Q +urn:mavedb:00000044-a-1#2946,NA,NA,p.Gly74Gln,-0.97,-1.02,2,G404Q +urn:mavedb:00000044-a-1#2947,NA,NA,p.Gly74Arg,-1.31,-1.29,1,G404R +urn:mavedb:00000044-a-1#3728,NA,NA,p.Lys94Glu,-2.54,-2.56,2,K424E +urn:mavedb:00000044-a-1#3729,NA,NA,p.Lys94Phe,-0.76,-0.9,1,K424F +urn:mavedb:00000044-a-1#3768,NA,NA,p.Leu95Glu,-4.84,-4.8,2,L425E +urn:mavedb:00000044-a-1#3769,NA,NA,p.Leu95Phe,-1.19,-1.38,1,L425F +urn:mavedb:00000044-a-1#3766,NA,NA,p.Leu95Asp,-4.84,-4.8,2,L425D +urn:mavedb:00000044-a-1#3760,NA,NA,p.Lys94*,NA,NA,2,K424 +urn:mavedb:00000044-a-1#3761,NA,NA,p.Leu95Ala,-2.69,-3.04,1,L425A +urn:mavedb:00000044-a-1#3799,NA,NA,p.Leu95*,NA,NA,1,L425 +urn:mavedb:00000044-a-1#3800,NA,NA,p.Leu95*,NA,NA,2,L425 +urn:mavedb:00000044-a-1#3730,NA,NA,p.Lys94Phe,-1.03,-0.9,2,K424F +urn:mavedb:00000044-a-1#3731,NA,NA,p.Lys94Gly,-0.75,-0.75,1,K424G +urn:mavedb:00000044-a-1#3732,NA,NA,p.Lys94Gly,-0.75,-0.75,2,K424G +urn:mavedb:00000044-a-1#3733,NA,NA,p.Lys94His,-0.03,-0.08,1,K424H +urn:mavedb:00000044-a-1#3734,NA,NA,p.Lys94His,-0.13,-0.08,2,K424H +urn:mavedb:00000044-a-1#3735,NA,NA,p.Lys94Ile,-2.09,-2.03,1,K424I +urn:mavedb:00000044-a-1#3736,NA,NA,p.Lys94Ile,-1.98,-2.03,2,K424I +urn:mavedb:00000044-a-1#3737,NA,NA,p.Lys94Leu,-0.98,-1.11,1,K424L +urn:mavedb:00000044-a-1#3738,NA,NA,p.Lys94Leu,-1.24,-1.11,2,K424L +urn:mavedb:00000044-a-1#3739,NA,NA,p.Lys94Met,-0.61,-0.68,1,K424M +urn:mavedb:00000044-a-1#3740,NA,NA,p.Lys94Met,-0.74,-0.68,2,K424M +urn:mavedb:00000044-a-1#3741,NA,NA,p.Lys94Asn,-0.28,-0.3,1,K424N +urn:mavedb:00000044-a-1#3742,NA,NA,p.Lys94Asn,-0.33,-0.3,2,K424N +urn:mavedb:00000044-a-1#3743,NA,NA,p.Lys94Pro,-1.25,-1.77,1,K424P +urn:mavedb:00000044-a-1#3744,NA,NA,p.Lys94Pro,-2.29,-1.77,2,K424P +urn:mavedb:00000044-a-1#3745,NA,NA,p.Lys94Gln,-0.54,-0.56,1,K424Q 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+urn:mavedb:00000044-a-1#3012,NA,NA,p.Glu76His,0.01,0,2,E406H +urn:mavedb:00000044-a-1#3013,NA,NA,p.Glu76Ile,-2.91,-2.12,1,E406I +urn:mavedb:00000044-a-1#3014,NA,NA,p.Glu76Ile,-1.34,-2.12,2,E406I +urn:mavedb:00000044-a-1#3015,NA,NA,p.Glu76Lys,-1.03,-0.96,1,E406K +urn:mavedb:00000044-a-1#3016,NA,NA,p.Glu76Lys,-0.89,-0.96,2,E406K +urn:mavedb:00000044-a-1#3017,NA,NA,p.Glu76Leu,-1.9,-1.4,1,E406L +urn:mavedb:00000044-a-1#3053,NA,NA,p.Val77His,-3.66,-3.09,1,V407H +urn:mavedb:00000044-a-1#3018,NA,NA,p.Glu76Leu,-0.9,-1.4,2,E406L +urn:mavedb:00000044-a-1#3019,NA,NA,p.Glu76Met,-0.4,-0.44,1,E406M +urn:mavedb:00000044-a-1#3020,NA,NA,p.Glu76Met,-0.49,-0.44,2,E406M +urn:mavedb:00000044-a-1#3021,NA,NA,p.Glu76Asn,-0.54,-0.56,1,E406N +urn:mavedb:00000044-a-1#3022,NA,NA,p.Glu76Asn,-0.58,-0.56,2,E406N +urn:mavedb:00000044-a-1#4040,NA,NA,p.Gly101*,NA,NA,2,G431 +urn:mavedb:00000044-a-1#4041,NA,NA,p.Cys102Ala,-1.63,-1.88,1,C432A +urn:mavedb:00000044-a-1#4042,NA,NA,p.Cys102Ala,-2.13,-1.88,2,C432A +urn:mavedb:00000044-a-1#4043,NA,NA,p.Cys102Asp,-4.57,-4.71,1,C432D +urn:mavedb:00000044-a-1#4044,NA,NA,p.Cys102Asp,-4.84,-4.71,2,C432D +urn:mavedb:00000044-a-1#4045,NA,NA,p.Cys102Glu,-4.76,-3.87,1,C432E +urn:mavedb:00000044-a-1#4046,NA,NA,p.Cys102Glu,-2.98,-3.87,2,C432E +urn:mavedb:00000044-a-1#4047,NA,NA,p.Cys102Phe,-0.75,-0.89,1,C432F +urn:mavedb:00000044-a-1#4048,NA,NA,p.Cys102Phe,-1.03,-0.89,2,C432F +urn:mavedb:00000044-a-1#4050,NA,NA,p.Cys102Gly,-4.84,-4.8,2,C432G +urn:mavedb:00000044-a-1#4051,NA,NA,p.Cys102His,-4.26,-4.55,1,C432H +urn:mavedb:00000044-a-1#4052,NA,NA,p.Cys102His,-4.84,-4.55,2,C432H +urn:mavedb:00000044-a-1#4053,NA,NA,p.Cys102Ile,-0.47,-0.47,1,C432I +urn:mavedb:00000044-a-1#4054,NA,NA,p.Cys102Ile,-0.48,-0.47,2,C432I +urn:mavedb:00000044-a-1#4055,NA,NA,p.Cys102Lys,-3.3,-3.88,1,C432K +urn:mavedb:00000044-a-1#4056,NA,NA,p.Cys102Lys,-4.45,-3.88,2,C432K +urn:mavedb:00000044-a-1#4057,NA,NA,p.Cys102Leu,-0.7,-0.73,1,C432L 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+urn:mavedb:00000044-a-1#933,NA,NA,p.Asn24His,-0.09,-0.07,1,N354H +urn:mavedb:00000044-a-1#934,NA,NA,p.Asn24His,-0.05,-0.07,2,N354H +urn:mavedb:00000044-a-1#935,NA,NA,p.Asn24Ile,-0.4,-0.39,1,N354I +urn:mavedb:00000044-a-1#936,NA,NA,p.Asn24Ile,-0.37,-0.39,2,N354I +urn:mavedb:00000044-a-1#937,NA,NA,p.Asn24Lys,0.02,0.03,1,N354K +urn:mavedb:00000044-a-1#938,NA,NA,p.Asn24Lys,0.04,0.03,2,N354K +urn:mavedb:00000044-a-1#939,NA,NA,p.Asn24Leu,-0.56,-0.56,1,N354L +urn:mavedb:00000044-a-1#940,NA,NA,p.Asn24Leu,-0.56,-0.56,2,N354L +urn:mavedb:00000044-a-1#941,NA,NA,p.Asn24Met,-0.2,-0.23,1,N354M +urn:mavedb:00000044-a-1#942,NA,NA,p.Asn24Met,-0.25,-0.23,2,N354M +urn:mavedb:00000044-a-1#943,NA,NA,p.Asn24Pro,-0.99,-0.9,1,N354P +urn:mavedb:00000044-a-1#944,NA,NA,p.Asn24Pro,-0.82,-0.9,2,N354P +urn:mavedb:00000044-a-1#945,NA,NA,p.Asn24Gln,0,0,1,N354Q +urn:mavedb:00000044-a-1#946,NA,NA,p.Asn24Gln,0,0,2,N354Q +urn:mavedb:00000044-a-1#947,NA,NA,p.Asn24Arg,0,0.05,1,N354R 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+urn:mavedb:00000044-a-1#1014,NA,NA,p.Lys26His,-0.16,-0.14,2,K356H +urn:mavedb:00000044-a-1#1015,NA,NA,p.Lys26Ile,-0.02,-0.04,1,K356I +urn:mavedb:00000044-a-1#1016,NA,NA,p.Lys26Ile,-0.06,-0.04,2,K356I +urn:mavedb:00000044-a-1#1017,NA,NA,p.Lys26Leu,-0.1,-0.07,1,K356L +urn:mavedb:00000044-a-1#1018,NA,NA,p.Lys26Leu,-0.04,-0.07,2,K356L +urn:mavedb:00000044-a-1#1019,NA,NA,p.Lys26Met,-0.01,-0.02,1,K356M +urn:mavedb:00000044-a-1#1020,NA,NA,p.Lys26Met,-0.03,-0.02,2,K356M +urn:mavedb:00000044-a-1#1021,NA,NA,p.Lys26Asn,-0.29,-0.28,1,K356N +urn:mavedb:00000044-a-1#1022,NA,NA,p.Lys26Asn,-0.26,-0.28,2,K356N +urn:mavedb:00000044-a-1#1023,NA,NA,p.Lys26Pro,-4.35,-4.2,1,K356P +urn:mavedb:00000044-a-1#1024,NA,NA,p.Lys26Pro,-4.05,-4.2,2,K356P +urn:mavedb:00000044-a-1#1025,NA,NA,p.Lys26Gln,-0.05,-0.12,1,K356Q +urn:mavedb:00000044-a-1#1026,NA,NA,p.Lys26Gln,-0.19,-0.12,2,K356Q +urn:mavedb:00000044-a-1#1027,NA,NA,p.Lys26Arg,0.01,0.03,1,K356R +urn:mavedb:00000044-a-1#1028,NA,NA,p.Lys26Arg,0.05,0.03,2,K356R 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+urn:mavedb:00000044-a-1#1188,NA,NA,p.Asn30Arg,-0.23,-0.19,2,N360R +urn:mavedb:00000044-a-1#1189,NA,NA,p.Asn30Ser,-0.18,-0.16,1,N360S +urn:mavedb:00000044-a-1#1090,NA,NA,p.Ile28Phe,0.01,0.1,2,I358F +urn:mavedb:00000044-a-1#1190,NA,NA,p.Asn30Ser,-0.14,-0.16,2,N360S +urn:mavedb:00000044-a-1#1191,NA,NA,p.Asn30Thr,-0.34,-0.35,1,N360T +urn:mavedb:00000044-a-1#1192,NA,NA,p.Asn30Thr,-0.36,-0.35,2,N360T +urn:mavedb:00000044-a-1#1193,NA,NA,p.Asn30Val,-0.73,-0.75,1,N360V +urn:mavedb:00000044-a-1#1225,NA,NA,p.Cys31Gln,-0.52,-0.57,1,C361Q +urn:mavedb:00000044-a-1#1064,NA,NA,p.Arg27Asn,-0.05,-0.03,2,R357N +urn:mavedb:00000044-a-1#1065,NA,NA,p.Arg27Pro,-0.12,-0.19,1,R357P +urn:mavedb:00000044-a-1#1066,NA,NA,p.Arg27Pro,-0.25,-0.19,2,R357P +urn:mavedb:00000044-a-1#1067,NA,NA,p.Arg27Gln,-0.05,-0.05,1,R357Q +urn:mavedb:00000044-a-1#1145,NA,NA,p.Ser29Pro,-0.12,-0.16,1,S359P +urn:mavedb:00000044-a-1#1148,NA,NA,p.Ser29Gln,-0.02,0.08,2,S359Q +urn:mavedb:00000044-a-1#1149,NA,NA,p.Ser29Arg,0.02,-0.03,1,S359R 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+urn:mavedb:00000044-a-1#1075,NA,NA,p.Arg27Trp,-0.09,-0.15,1,R357W +urn:mavedb:00000044-a-1#1167,NA,NA,p.Asn30Glu,-0.16,-0.13,1,N360E +urn:mavedb:00000044-a-1#1174,NA,NA,p.Asn30His,-0.04,-0.04,2,N360H +urn:mavedb:00000044-a-1#1176,NA,NA,p.Asn30Ile,-0.84,-0.71,2,N360I +urn:mavedb:00000044-a-1#1177,NA,NA,p.Asn30Lys,-0.11,-0.12,1,N360K +urn:mavedb:00000044-a-1#1179,NA,NA,p.Asn30Leu,-0.4,-0.59,1,N360L +urn:mavedb:00000044-a-1#1181,NA,NA,p.Asn30Met,-0.48,-0.38,1,N360M +urn:mavedb:00000044-a-1#1182,NA,NA,p.Asn30Met,-0.29,-0.38,2,N360M +urn:mavedb:00000044-a-1#1183,NA,NA,p.Asn30Pro,-0.02,-0.04,1,N360P +urn:mavedb:00000044-a-1#1184,NA,NA,p.Asn30Pro,-0.05,-0.04,2,N360P +urn:mavedb:00000044-a-1#1123,NA,NA,p.Ser29Cys,-0.04,-0.05,1,S359C +urn:mavedb:00000044-a-1#1124,NA,NA,p.Ser29Cys,-0.05,-0.05,2,S359C +urn:mavedb:00000044-a-1#1125,NA,NA,p.Ser29Asp,-0.04,-0.01,1,S359D +urn:mavedb:00000044-a-1#1147,NA,NA,p.Ser29Gln,0.18,0.08,1,S359Q +urn:mavedb:00000044-a-1#1127,NA,NA,p.Ser29Glu,-0.02,-0.13,1,S359E +urn:mavedb:00000044-a-1#1128,NA,NA,p.Ser29Glu,-0.24,-0.13,2,S359E +urn:mavedb:00000044-a-1#1129,NA,NA,p.Ser29Phe,-0.04,-0.08,1,S359F +urn:mavedb:00000044-a-1#1136,NA,NA,p.Ser29Ile,-0.14,-0.15,2,S359I +urn:mavedb:00000044-a-1#1138,NA,NA,p.Ser29Lys,-0.07,-0.06,2,S359K +urn:mavedb:00000044-a-1#1141,NA,NA,p.Ser29Met,-0.14,-0.16,1,S359M +urn:mavedb:00000044-a-1#1076,NA,NA,p.Arg27Trp,-0.2,-0.15,2,R357W +urn:mavedb:00000044-a-1#1077,NA,NA,p.Arg27Tyr,-0.04,-0.06,1,R357Y +urn:mavedb:00000044-a-1#1078,NA,NA,p.Arg27Tyr,-0.08,-0.06,2,R357Y +urn:mavedb:00000044-a-1#1079,NA,NA,p.Arg27*,NA,NA,1,R357 +urn:mavedb:00000044-a-1#1144,NA,NA,p.Ser29Asn,-0.02,0.04,2,S359N +urn:mavedb:00000044-a-1#1080,NA,NA,p.Arg27*,NA,NA,2,R357 +urn:mavedb:00000044-a-1#1126,NA,NA,p.Ser29Asp,0.03,-0.01,2,S359D +urn:mavedb:00000044-a-1#1081,NA,NA,p.Ile28Ala,-0.74,-0.7,1,I358A +urn:mavedb:00000044-a-1#1082,NA,NA,p.Ile28Ala,-0.66,-0.7,2,I358A +urn:mavedb:00000044-a-1#1130,NA,NA,p.Ser29Phe,-0.12,-0.08,2,S359F +urn:mavedb:00000044-a-1#1131,NA,NA,p.Ser29Gly,-0.12,-0.08,1,S359G +urn:mavedb:00000044-a-1#1132,NA,NA,p.Ser29Gly,-0.03,-0.08,2,S359G +urn:mavedb:00000044-a-1#1083,NA,NA,p.Ile28Cys,-0.36,-0.41,1,I358C +urn:mavedb:00000044-a-1#1133,NA,NA,p.Ser29His,-0.04,-0.01,1,S359H +urn:mavedb:00000044-a-1#1134,NA,NA,p.Ser29His,0.02,-0.01,2,S359H +urn:mavedb:00000044-a-1#1135,NA,NA,p.Ser29Ile,-0.16,-0.15,1,S359I +urn:mavedb:00000044-a-1#1137,NA,NA,p.Ser29Lys,-0.04,-0.06,1,S359K +urn:mavedb:00000044-a-1#1139,NA,NA,p.Ser29Leu,-0.25,-0.29,1,S359L +urn:mavedb:00000044-a-1#1140,NA,NA,p.Ser29Leu,-0.34,-0.29,2,S359L +urn:mavedb:00000044-a-1#1142,NA,NA,p.Ser29Met,-0.18,-0.16,2,S359M +urn:mavedb:00000044-a-1#1143,NA,NA,p.Ser29Asn,0.1,0.04,1,S359N +urn:mavedb:00000044-a-1#1084,NA,NA,p.Ile28Cys,-0.45,-0.41,2,I358C +urn:mavedb:00000044-a-1#1146,NA,NA,p.Ser29Pro,-0.21,-0.16,2,S359P +urn:mavedb:00000044-a-1#1085,NA,NA,p.Ile28Asp,-1.94,-1.81,1,I358D +urn:mavedb:00000044-a-1#1094,NA,NA,p.Ile28His,-0.74,-0.64,2,I358H +urn:mavedb:00000044-a-1#1205,NA,NA,p.Cys31Glu,-0.57,-0.58,1,C361E +urn:mavedb:00000044-a-1#1230,NA,NA,p.Cys31Ser,-0.62,-0.61,2,C361S +urn:mavedb:00000044-a-1#1206,NA,NA,p.Cys31Glu,-0.59,-0.58,2,C361E +urn:mavedb:00000044-a-1#1231,NA,NA,p.Cys31Thr,-0.62,-0.61,1,C361T +urn:mavedb:00000044-a-1#1237,NA,NA,p.Cys31Tyr,-0.56,-0.64,1,C361Y +urn:mavedb:00000044-a-1#1207,NA,NA,p.Cys31Phe,-0.55,-0.59,1,C361F +urn:mavedb:00000044-a-1#1208,NA,NA,p.Cys31Phe,-0.62,-0.59,2,C361F +urn:mavedb:00000044-a-1#1232,NA,NA,p.Cys31Thr,-0.61,-0.61,2,C361T +urn:mavedb:00000044-a-1#1239,NA,NA,p.Cys31*,NA,NA,1,C361 +urn:mavedb:00000044-a-1#1209,NA,NA,p.Cys31Gly,-0.71,-0.72,1,C361G +urn:mavedb:00000044-a-1#1210,NA,NA,p.Cys31Gly,-0.73,-0.72,2,C361G +urn:mavedb:00000044-a-1#1211,NA,NA,p.Cys31His,-0.54,-0.69,1,C361H +urn:mavedb:00000044-a-1#1212,NA,NA,p.Cys31His,-0.84,-0.69,2,C361H +urn:mavedb:00000044-a-1#1194,NA,NA,p.Asn30Val,-0.76,-0.75,2,N360V +urn:mavedb:00000044-a-1#1195,NA,NA,p.Asn30Trp,-0.2,-0.25,1,N360W +urn:mavedb:00000044-a-1#1196,NA,NA,p.Asn30Trp,-0.31,-0.25,2,N360W +urn:mavedb:00000044-a-1#1197,NA,NA,p.Asn30Tyr,-0.29,-0.33,1,N360Y +urn:mavedb:00000044-a-1#1198,NA,NA,p.Asn30Tyr,-0.37,-0.33,2,N360Y +urn:mavedb:00000044-a-1#1199,NA,NA,p.Asn30*,NA,NA,1,N360 +urn:mavedb:00000044-a-1#1200,NA,NA,p.Asn30*,NA,NA,2,N360 +urn:mavedb:00000044-a-1#1227,NA,NA,p.Cys31Arg,-0.66,-0.66,1,C361R +urn:mavedb:00000044-a-1#1091,NA,NA,p.Ile28Gly,-0.63,-0.74,1,I358G +urn:mavedb:00000044-a-1#1201,NA,NA,p.Cys31Ala,-0.55,-0.59,1,C361A +urn:mavedb:00000044-a-1#1228,NA,NA,p.Cys31Arg,-0.64,-0.66,2,C361R +urn:mavedb:00000044-a-1#1092,NA,NA,p.Ile28Gly,-0.86,-0.74,2,I358G +urn:mavedb:00000044-a-1#1202,NA,NA,p.Cys31Ala,-0.63,-0.59,2,C361A +urn:mavedb:00000044-a-1#1229,NA,NA,p.Cys31Ser,-0.6,-0.61,1,C361S +urn:mavedb:00000044-a-1#1203,NA,NA,p.Cys31Asp,-1.14,-0.86,1,C361D +urn:mavedb:00000044-a-1#1093,NA,NA,p.Ile28His,-0.54,-0.64,1,I358H +urn:mavedb:00000044-a-1#1204,NA,NA,p.Cys31Asp,-0.58,-0.86,2,C361D +urn:mavedb:00000044-a-1#1299,NA,NA,p.Ala33Met,-0.14,-0.14,1,A363M +urn:mavedb:00000044-a-1#1300,NA,NA,p.Ala33Met,-0.15,-0.14,2,A363M +urn:mavedb:00000044-a-1#1301,NA,NA,p.Ala33Asn,-0.48,-0.43,1,A363N +urn:mavedb:00000044-a-1#1328,NA,NA,p.Asp34Phe,-0.83,-0.77,2,D364F +urn:mavedb:00000044-a-1#1329,NA,NA,p.Asp34Gly,-0.64,-0.62,1,D364G +urn:mavedb:00000044-a-1#1302,NA,NA,p.Ala33Asn,-0.37,-0.43,2,A363N +urn:mavedb:00000044-a-1#1303,NA,NA,p.Ala33Pro,-0.13,-0.15,1,A363P +urn:mavedb:00000044-a-1#1330,NA,NA,p.Asp34Gly,-0.59,-0.62,2,D364G +urn:mavedb:00000044-a-1#1213,NA,NA,p.Cys31Ile,-0.68,-0.66,1,C361I +urn:mavedb:00000044-a-1#1214,NA,NA,p.Cys31Ile,-0.63,-0.66,2,C361I +urn:mavedb:00000044-a-1#1215,NA,NA,p.Cys31Lys,-0.62,-0.62,1,C361K +urn:mavedb:00000044-a-1#1216,NA,NA,p.Cys31Lys,-0.62,-0.62,2,C361K +urn:mavedb:00000044-a-1#1217,NA,NA,p.Cys31Leu,-0.68,-0.7,1,C361L +urn:mavedb:00000044-a-1#1234,NA,NA,p.Cys31Val,-0.66,-0.58,2,C361V +urn:mavedb:00000044-a-1#1241,NA,NA,p.Val32Ala,-0.04,-0.09,1,V362A +urn:mavedb:00000044-a-1#1218,NA,NA,p.Cys31Leu,-0.72,-0.7,2,C361L +urn:mavedb:00000044-a-1#1235,NA,NA,p.Cys31Trp,-0.63,-0.7,1,C361W +urn:mavedb:00000044-a-1#1246,NA,NA,p.Val32Asp,-0.22,-0.18,2,V362D +urn:mavedb:00000044-a-1#1220,NA,NA,p.Cys31Met,-0.67,-0.67,2,C361M +urn:mavedb:00000044-a-1#1236,NA,NA,p.Cys31Trp,-0.77,-0.7,2,C361W +urn:mavedb:00000044-a-1#1222,NA,NA,p.Cys31Asn,-0.66,-0.59,2,C361N +urn:mavedb:00000044-a-1#1223,NA,NA,p.Cys31Pro,-0.33,-0.38,1,C361P +urn:mavedb:00000044-a-1#1224,NA,NA,p.Cys31Pro,-0.44,-0.38,2,C361P +urn:mavedb:00000044-a-1#1219,NA,NA,p.Cys31Met,-0.67,-0.67,1,C361M +urn:mavedb:00000044-a-1#1221,NA,NA,p.Cys31Asn,-0.52,-0.59,1,C361N +urn:mavedb:00000044-a-1#1226,NA,NA,p.Cys31Gln,-0.62,-0.57,2,C361Q +urn:mavedb:00000044-a-1#1233,NA,NA,p.Cys31Val,-0.51,-0.58,1,C361V +urn:mavedb:00000044-a-1#1095,NA,NA,p.Ile28Lys,-1.15,-1.25,1,I358K +urn:mavedb:00000044-a-1#1238,NA,NA,p.Cys31Tyr,-0.72,-0.64,2,C361Y +urn:mavedb:00000044-a-1#1096,NA,NA,p.Ile28Lys,-1.34,-1.25,2,I358K +urn:mavedb:00000044-a-1#1240,NA,NA,p.Cys31*,NA,NA,2,C361 +urn:mavedb:00000044-a-1#1242,NA,NA,p.Val32Ala,-0.14,-0.09,2,V362A +urn:mavedb:00000044-a-1#1243,NA,NA,p.Val32Cys,-0.07,-0.09,1,V362C +urn:mavedb:00000044-a-1#1244,NA,NA,p.Val32Cys,-0.12,-0.09,2,V362C +urn:mavedb:00000044-a-1#1245,NA,NA,p.Val32Asp,-0.15,-0.18,1,V362D +urn:mavedb:00000044-a-1#1247,NA,NA,p.Val32Glu,-0.04,-0.05,1,V362E +urn:mavedb:00000044-a-1#1248,NA,NA,p.Val32Glu,-0.05,-0.05,2,V362E +urn:mavedb:00000044-a-1#1249,NA,NA,p.Val32Phe,0.06,-0.01,1,V362F +urn:mavedb:00000044-a-1#1250,NA,NA,p.Val32Phe,-0.07,-0.01,2,V362F +urn:mavedb:00000044-a-1#1251,NA,NA,p.Val32Gly,-0.21,-0.21,1,V362G +urn:mavedb:00000044-a-1#1252,NA,NA,p.Val32Gly,-0.21,-0.21,2,V362G +urn:mavedb:00000044-a-1#1253,NA,NA,p.Val32His,-0.05,-0.05,1,V362H +urn:mavedb:00000044-a-1#1254,NA,NA,p.Val32His,-0.04,-0.05,2,V362H +urn:mavedb:00000044-a-1#1282,NA,NA,p.Ala33Cys,-0.12,-0.09,2,A363C +urn:mavedb:00000044-a-1#1255,NA,NA,p.Val32Ile,0,0.04,1,V362I +urn:mavedb:00000044-a-1#1284,NA,NA,p.Ala33Asp,-0.68,-0.66,2,A363D +urn:mavedb:00000044-a-1#1298,NA,NA,p.Ala33Leu,-0.08,-0.06,2,A363L +urn:mavedb:00000044-a-1#1097,NA,NA,p.Ile28Leu,-0.03,0,1,I358L +urn:mavedb:00000044-a-1#1256,NA,NA,p.Val32Ile,0.09,0.04,2,V362I +urn:mavedb:00000044-a-1#1257,NA,NA,p.Val32Lys,-0.03,-0.02,1,V362K +urn:mavedb:00000044-a-1#1258,NA,NA,p.Val32Lys,-0.02,-0.02,2,V362K +urn:mavedb:00000044-a-1#1259,NA,NA,p.Val32Leu,-0.02,-0.03,1,V362L +urn:mavedb:00000044-a-1#1276,NA,NA,p.Val32Trp,0,0,2,V362W +urn:mavedb:00000044-a-1#1286,NA,NA,p.Ala33Glu,-0.53,-0.47,2,A363E +urn:mavedb:00000044-a-1#1260,NA,NA,p.Val32Leu,-0.04,-0.03,2,V362L +urn:mavedb:00000044-a-1#1261,NA,NA,p.Val32Met,0.09,0.03,1,V362M +urn:mavedb:00000044-a-1#1262,NA,NA,p.Val32Met,-0.03,0.03,2,V362M +urn:mavedb:00000044-a-1#1278,NA,NA,p.Val32Tyr,0,0,2,V362Y +urn:mavedb:00000044-a-1#1287,NA,NA,p.Ala33Phe,-0.1,-0.12,1,A363F +urn:mavedb:00000044-a-1#1263,NA,NA,p.Val32Asn,-0.05,-0.1,1,V362N +urn:mavedb:00000044-a-1#1289,NA,NA,p.Ala33Gly,-0.15,-0.13,1,A363G +urn:mavedb:00000044-a-1#1295,NA,NA,p.Ala33Lys,-0.5,-0.54,1,A363K +urn:mavedb:00000044-a-1#1264,NA,NA,p.Val32Asn,-0.15,-0.1,2,V362N +urn:mavedb:00000044-a-1#1265,NA,NA,p.Val32Pro,-0.55,-0.51,1,V362P +urn:mavedb:00000044-a-1#1266,NA,NA,p.Val32Pro,-0.47,-0.51,2,V362P +urn:mavedb:00000044-a-1#1267,NA,NA,p.Val32Gln,-0.06,-0.03,1,V362Q +urn:mavedb:00000044-a-1#1268,NA,NA,p.Val32Gln,0,-0.03,2,V362Q +urn:mavedb:00000044-a-1#1269,NA,NA,p.Val32Arg,0.02,0,1,V362R +urn:mavedb:00000044-a-1#1296,NA,NA,p.Ala33Lys,-0.58,-0.54,2,A363K +urn:mavedb:00000044-a-1#1098,NA,NA,p.Ile28Leu,0.02,0,2,I358L +urn:mavedb:00000044-a-1#1321,NA,NA,p.Asp34Ala,-0.62,-0.62,1,D364A +urn:mavedb:00000044-a-1#1099,NA,NA,p.Ile28Met,0.02,-0.01,1,I358M +urn:mavedb:00000044-a-1#1270,NA,NA,p.Val32Arg,-0.02,0,2,V362R +urn:mavedb:00000044-a-1#1271,NA,NA,p.Val32Ser,-0.09,-0.1,1,V362S +urn:mavedb:00000044-a-1#1272,NA,NA,p.Val32Ser,-0.12,-0.1,2,V362S +urn:mavedb:00000044-a-1#1100,NA,NA,p.Ile28Met,-0.04,-0.01,2,I358M +urn:mavedb:00000044-a-1#1273,NA,NA,p.Val32Thr,0.16,0.08,1,V362T +urn:mavedb:00000044-a-1#1274,NA,NA,p.Val32Thr,-0.01,0.08,2,V362T +urn:mavedb:00000044-a-1#1275,NA,NA,p.Val32Trp,0,0,1,V362W +urn:mavedb:00000044-a-1#1277,NA,NA,p.Val32Tyr,-0.01,0,1,V362Y +urn:mavedb:00000044-a-1#1279,NA,NA,p.Val32*,NA,NA,1,V362 +urn:mavedb:00000044-a-1#1280,NA,NA,p.Val32*,NA,NA,2,V362 +urn:mavedb:00000044-a-1#1281,NA,NA,p.Ala33Cys,-0.07,-0.09,1,A363C +urn:mavedb:00000044-a-1#1283,NA,NA,p.Ala33Asp,-0.63,-0.66,1,A363D +urn:mavedb:00000044-a-1#1285,NA,NA,p.Ala33Glu,-0.41,-0.47,1,A363E +urn:mavedb:00000044-a-1#1288,NA,NA,p.Ala33Phe,-0.15,-0.12,2,A363F +urn:mavedb:00000044-a-1#1290,NA,NA,p.Ala33Gly,-0.12,-0.13,2,A363G +urn:mavedb:00000044-a-1#1305,NA,NA,p.Ala33Gln,-0.07,-0.02,1,A363Q +urn:mavedb:00000044-a-1#1306,NA,NA,p.Ala33Gln,0.03,-0.02,2,A363Q +urn:mavedb:00000044-a-1#1310,NA,NA,p.Ala33Ser,-0.21,-0.19,2,A363S +urn:mavedb:00000044-a-1#1307,NA,NA,p.Ala33Arg,-0.53,-0.56,1,A363R +urn:mavedb:00000044-a-1#1332,NA,NA,p.Asp34His,-0.52,-0.5,2,D364H +urn:mavedb:00000044-a-1#1313,NA,NA,p.Ala33Val,-0.11,-0.13,1,A363V +urn:mavedb:00000044-a-1#1314,NA,NA,p.Ala33Val,-0.15,-0.13,2,A363V +urn:mavedb:00000044-a-1#1349,NA,NA,p.Asp34Ser,-0.35,-0.39,1,D364S +urn:mavedb:00000044-a-1#1354,NA,NA,p.Asp34Val,-0.65,-0.64,2,D364V +urn:mavedb:00000044-a-1#1355,NA,NA,p.Asp34Trp,-0.55,-0.62,1,D364W +urn:mavedb:00000044-a-1#1356,NA,NA,p.Asp34Trp,-0.68,-0.62,2,D364W +urn:mavedb:00000044-a-1#1104,NA,NA,p.Ile28Pro,-1.93,-2.18,2,I358P +urn:mavedb:00000044-a-1#1357,NA,NA,p.Asp34Tyr,-0.56,-0.55,1,D364Y +urn:mavedb:00000044-a-1#1358,NA,NA,p.Asp34Tyr,-0.55,-0.55,2,D364Y +urn:mavedb:00000044-a-1#1431,NA,NA,p.Ser36Thr,0,-0.01,1,S366T +urn:mavedb:00000044-a-1#1316,NA,NA,p.Ala33Trp,0.04,0.06,2,A363W +urn:mavedb:00000044-a-1#1432,NA,NA,p.Ser36Thr,-0.01,-0.01,2,S366T +urn:mavedb:00000044-a-1#1317,NA,NA,p.Ala33Tyr,-0.15,-0.17,1,A363Y +urn:mavedb:00000044-a-1#1315,NA,NA,p.Ala33Trp,0.08,0.06,1,A363W +urn:mavedb:00000044-a-1#1105,NA,NA,p.Ile28Gln,-0.87,-0.93,1,I358Q +urn:mavedb:00000044-a-1#1318,NA,NA,p.Ala33Tyr,-0.2,-0.17,2,A363Y +urn:mavedb:00000044-a-1#1106,NA,NA,p.Ile28Gln,-1,-0.93,2,I358Q +urn:mavedb:00000044-a-1#1319,NA,NA,p.Ala33*,NA,NA,1,A363 +urn:mavedb:00000044-a-1#1107,NA,NA,p.Ile28Arg,-1.2,-1.3,1,I358R +urn:mavedb:00000044-a-1#1433,NA,NA,p.Ser36Val,0,-0.05,1,S366V +urn:mavedb:00000044-a-1#1322,NA,NA,p.Asp34Ala,-0.63,-0.62,2,D364A +urn:mavedb:00000044-a-1#1294,NA,NA,p.Ala33Ile,-0.3,-0.25,2,A363I +urn:mavedb:00000044-a-1#1110,NA,NA,p.Ile28Ser,-0.83,-0.78,2,I358S +urn:mavedb:00000044-a-1#1111,NA,NA,p.Ile28Thr,-0.74,-0.83,1,I358T +urn:mavedb:00000044-a-1#1112,NA,NA,p.Ile28Thr,-0.92,-0.83,2,I358T +urn:mavedb:00000044-a-1#1113,NA,NA,p.Ile28Val,-0.15,-0.14,1,I358V +urn:mavedb:00000044-a-1#1114,NA,NA,p.Ile28Val,-0.13,-0.14,2,I358V +urn:mavedb:00000044-a-1#1115,NA,NA,p.Ile28Trp,0.11,0.07,1,I358W +urn:mavedb:00000044-a-1#1116,NA,NA,p.Ile28Trp,0.04,0.07,2,I358W +urn:mavedb:00000044-a-1#1117,NA,NA,p.Ile28Tyr,-0.04,-0.01,1,I358Y +urn:mavedb:00000044-a-1#1118,NA,NA,p.Ile28Tyr,0.02,-0.01,2,I358Y +urn:mavedb:00000044-a-1#1119,NA,NA,p.Ile28*,NA,NA,1,I358 +urn:mavedb:00000044-a-1#1120,NA,NA,p.Ile28*,NA,NA,2,I358 +urn:mavedb:00000044-a-1#1121,NA,NA,p.Ser29Ala,-0.07,-0.02,1,S359A +urn:mavedb:00000044-a-1#1561,NA,NA,p.Asn40Ala,-0.16,-0.1,1,N370A +urn:mavedb:00000044-a-1#860,NA,NA,p.Ala22Met,-0.06,-0.02,2,A352M +urn:mavedb:00000044-a-1#861,NA,NA,p.Ala22Asn,-0.05,-0.04,1,A352N +urn:mavedb:00000044-a-1#862,NA,NA,p.Ala22Asn,-0.04,-0.04,2,A352N +urn:mavedb:00000044-a-1#863,NA,NA,p.Ala22Pro,-3.05,-3.21,1,A352P +urn:mavedb:00000044-a-1#864,NA,NA,p.Ala22Pro,-3.38,-3.21,2,A352P +urn:mavedb:00000044-a-1#175,NA,NA,p.Leu5Ile,0,-0.02,1,L335I +urn:mavedb:00000044-a-1#176,NA,NA,p.Leu5Ile,-0.04,-0.02,2,L335I +urn:mavedb:00000044-a-1#177,NA,NA,p.Leu5Lys,-0.06,-0.03,1,L335K +urn:mavedb:00000044-a-1#178,NA,NA,p.Leu5Lys,0,-0.03,2,L335K +urn:mavedb:00000044-a-1#179,NA,NA,p.Leu5Met,0.02,0.01,1,L335M +urn:mavedb:00000044-a-1#180,NA,NA,p.Leu5Met,0,0.01,2,L335M +urn:mavedb:00000044-a-1#1333,NA,NA,p.Asp34Ile,-0.68,-0.69,1,D364I +urn:mavedb:00000044-a-1#1334,NA,NA,p.Asp34Ile,-0.69,-0.69,2,D364I +urn:mavedb:00000044-a-1#1335,NA,NA,p.Asp34Lys,-0.44,-0.45,1,D364K +urn:mavedb:00000044-a-1#1336,NA,NA,p.Asp34Lys,-0.46,-0.45,2,D364K +urn:mavedb:00000044-a-1#1337,NA,NA,p.Asp34Leu,-1,-0.91,1,D364L +urn:mavedb:00000044-a-1#1338,NA,NA,p.Asp34Leu,-0.81,-0.91,2,D364L +urn:mavedb:00000044-a-1#1339,NA,NA,p.Asp34Met,-0.76,-0.82,1,D364M +urn:mavedb:00000044-a-1#1340,NA,NA,p.Asp34Met,-0.87,-0.82,2,D364M +urn:mavedb:00000044-a-1#1341,NA,NA,p.Asp34Asn,-0.22,-0.22,1,D364N +urn:mavedb:00000044-a-1#1312,NA,NA,p.Ala33Thr,-0.15,-0.18,2,A363T +urn:mavedb:00000044-a-1#1311,NA,NA,p.Ala33Thr,-0.21,-0.18,1,A363T +urn:mavedb:00000044-a-1#1342,NA,NA,p.Asp34Asn,-0.22,-0.22,2,D364N +urn:mavedb:00000044-a-1#1343,NA,NA,p.Asp34Pro,-0.52,-0.57,1,D364P +urn:mavedb:00000044-a-1#1344,NA,NA,p.Asp34Pro,-0.62,-0.57,2,D364P +urn:mavedb:00000044-a-1#1345,NA,NA,p.Asp34Gln,-0.52,-0.46,1,D364Q +urn:mavedb:00000044-a-1#1346,NA,NA,p.Asp34Gln,-0.41,-0.46,2,D364Q +urn:mavedb:00000044-a-1#1101,NA,NA,p.Ile28Asn,-0.84,-0.91,1,I358N +urn:mavedb:00000044-a-1#1102,NA,NA,p.Ile28Asn,-0.98,-0.91,2,I358N +urn:mavedb:00000044-a-1#1347,NA,NA,p.Asp34Arg,-0.56,-0.58,1,D364R +urn:mavedb:00000044-a-1#1348,NA,NA,p.Asp34Arg,-0.6,-0.58,2,D364R +urn:mavedb:00000044-a-1#1103,NA,NA,p.Ile28Pro,-2.43,-2.18,1,I358P +urn:mavedb:00000044-a-1#1434,NA,NA,p.Ser36Val,-0.1,-0.05,2,S366V +urn:mavedb:00000044-a-1#1350,NA,NA,p.Asp34Ser,-0.42,-0.39,2,D364S +urn:mavedb:00000044-a-1#1351,NA,NA,p.Asp34Thr,-0.56,-0.57,1,D364T +urn:mavedb:00000044-a-1#1435,NA,NA,p.Ser36Trp,-0.12,-0.12,1,S366W +urn:mavedb:00000044-a-1#1108,NA,NA,p.Ile28Arg,-1.39,-1.3,2,I358R +urn:mavedb:00000044-a-1#1109,NA,NA,p.Ile28Ser,-0.72,-0.78,1,I358S +urn:mavedb:00000044-a-1#1436,NA,NA,p.Ser36Trp,-0.12,-0.12,2,S366W +urn:mavedb:00000044-a-1#1122,NA,NA,p.Ser29Ala,0.04,-0.02,2,S359A +urn:mavedb:00000044-a-1#1291,NA,NA,p.Ala33His,-0.21,-0.21,1,A363H +urn:mavedb:00000044-a-1#1292,NA,NA,p.Ala33His,-0.2,-0.21,2,A363H +urn:mavedb:00000044-a-1#1293,NA,NA,p.Ala33Ile,-0.19,-0.25,1,A363I +urn:mavedb:00000044-a-1#1352,NA,NA,p.Asp34Thr,-0.59,-0.57,2,D364T +urn:mavedb:00000044-a-1#1353,NA,NA,p.Asp34Val,-0.63,-0.64,1,D364V +urn:mavedb:00000044-a-1#1323,NA,NA,p.Asp34Cys,-0.55,-0.46,1,D364C +urn:mavedb:00000044-a-1#1324,NA,NA,p.Asp34Cys,-0.36,-0.46,2,D364C +urn:mavedb:00000044-a-1#1325,NA,NA,p.Asp34Glu,-0.24,-0.3,1,D364E +urn:mavedb:00000044-a-1#1326,NA,NA,p.Asp34Glu,-0.36,-0.3,2,D364E +urn:mavedb:00000044-a-1#1327,NA,NA,p.Asp34Phe,-0.7,-0.77,1,D364F +urn:mavedb:00000044-a-1#1359,NA,NA,p.Asp34*,NA,NA,1,D364 +urn:mavedb:00000044-a-1#1360,NA,NA,p.Asp34*,NA,NA,2,D364 +urn:mavedb:00000044-a-1#1361,NA,NA,p.Tyr35Ala,-0.31,-0.29,1,Y365A +urn:mavedb:00000044-a-1#1362,NA,NA,p.Tyr35Ala,-0.28,-0.29,2,Y365A +urn:mavedb:00000044-a-1#1363,NA,NA,p.Tyr35Cys,-0.4,-0.45,1,Y365C +urn:mavedb:00000044-a-1#1364,NA,NA,p.Tyr35Cys,-0.5,-0.45,2,Y365C +urn:mavedb:00000044-a-1#1365,NA,NA,p.Tyr35Asp,-0.58,-0.68,1,Y365D +urn:mavedb:00000044-a-1#1366,NA,NA,p.Tyr35Asp,-0.77,-0.68,2,Y365D +urn:mavedb:00000044-a-1#1367,NA,NA,p.Tyr35Glu,-0.57,-0.61,1,Y365E +urn:mavedb:00000044-a-1#1368,NA,NA,p.Tyr35Glu,-0.65,-0.61,2,Y365E +urn:mavedb:00000044-a-1#1369,NA,NA,p.Tyr35Phe,-0.06,0,1,Y365F +urn:mavedb:00000044-a-1#1370,NA,NA,p.Tyr35Phe,0.05,0,2,Y365F +urn:mavedb:00000044-a-1#1371,NA,NA,p.Tyr35Gly,-0.37,-0.37,1,Y365G +urn:mavedb:00000044-a-1#1372,NA,NA,p.Tyr35Gly,-0.38,-0.37,2,Y365G +urn:mavedb:00000044-a-1#1373,NA,NA,p.Tyr35His,-0.52,-0.55,1,Y365H +urn:mavedb:00000044-a-1#1374,NA,NA,p.Tyr35His,-0.58,-0.55,2,Y365H +urn:mavedb:00000044-a-1#1375,NA,NA,p.Tyr35Ile,-0.05,-0.05,1,Y365I +urn:mavedb:00000044-a-1#1376,NA,NA,p.Tyr35Ile,-0.04,-0.05,2,Y365I +urn:mavedb:00000044-a-1#1377,NA,NA,p.Tyr35Lys,-0.61,-0.6,1,Y365K +urn:mavedb:00000044-a-1#1378,NA,NA,p.Tyr35Lys,-0.6,-0.6,2,Y365K +urn:mavedb:00000044-a-1#1379,NA,NA,p.Tyr35Leu,0.01,0,1,Y365L +urn:mavedb:00000044-a-1#1380,NA,NA,p.Tyr35Leu,-0.02,0,2,Y365L +urn:mavedb:00000044-a-1#1381,NA,NA,p.Tyr35Met,0.01,0.03,1,Y365M +urn:mavedb:00000044-a-1#1382,NA,NA,p.Tyr35Met,0.04,0.03,2,Y365M +urn:mavedb:00000044-a-1#1383,NA,NA,p.Tyr35Asn,-0.55,-0.55,1,Y365N +urn:mavedb:00000044-a-1#1384,NA,NA,p.Tyr35Asn,-0.55,-0.55,2,Y365N +urn:mavedb:00000044-a-1#1385,NA,NA,p.Tyr35Pro,-0.34,-0.38,1,Y365P +urn:mavedb:00000044-a-1#1386,NA,NA,p.Tyr35Pro,-0.41,-0.38,2,Y365P +urn:mavedb:00000044-a-1#1387,NA,NA,p.Tyr35Gln,-0.54,-0.6,1,Y365Q +urn:mavedb:00000044-a-1#1388,NA,NA,p.Tyr35Gln,-0.67,-0.6,2,Y365Q +urn:mavedb:00000044-a-1#1389,NA,NA,p.Tyr35Arg,-0.57,-0.61,1,Y365R +urn:mavedb:00000044-a-1#1390,NA,NA,p.Tyr35Arg,-0.66,-0.61,2,Y365R +urn:mavedb:00000044-a-1#1391,NA,NA,p.Tyr35Ser,-0.44,-0.42,1,Y365S +urn:mavedb:00000044-a-1#1392,NA,NA,p.Tyr35Ser,-0.4,-0.42,2,Y365S +urn:mavedb:00000044-a-1#1393,NA,NA,p.Tyr35Thr,-0.35,-0.33,1,Y365T +urn:mavedb:00000044-a-1#1394,NA,NA,p.Tyr35Thr,-0.31,-0.33,2,Y365T +urn:mavedb:00000044-a-1#1395,NA,NA,p.Tyr35Val,-0.05,-0.11,1,Y365V +urn:mavedb:00000044-a-1#1396,NA,NA,p.Tyr35Val,-0.16,-0.11,2,Y365V +urn:mavedb:00000044-a-1#1397,NA,NA,p.Tyr35Trp,0.03,-0.01,1,Y365W +urn:mavedb:00000044-a-1#1398,NA,NA,p.Tyr35Trp,-0.06,-0.01,2,Y365W +urn:mavedb:00000044-a-1#1399,NA,NA,p.Tyr35*,NA,NA,1,Y365 +urn:mavedb:00000044-a-1#1400,NA,NA,p.Tyr35*,NA,NA,2,Y365 +urn:mavedb:00000044-a-1#1401,NA,NA,p.Ser36Ala,-0.02,-0.03,1,S366A +urn:mavedb:00000044-a-1#1402,NA,NA,p.Ser36Ala,-0.04,-0.03,2,S366A 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+urn:mavedb:00000044-a-1#1806,NA,NA,p.Thr46Asp,-0.24,-0.98,2,T376D +urn:mavedb:00000044-a-1#1807,NA,NA,p.Thr46Glu,-0.08,-0.13,1,T376E +urn:mavedb:00000044-a-1#1808,NA,NA,p.Thr46Glu,-0.18,-0.13,2,T376E +urn:mavedb:00000044-a-1#1809,NA,NA,p.Thr46Phe,-0.11,-0.12,1,T376F +urn:mavedb:00000044-a-1#1810,NA,NA,p.Thr46Phe,-0.14,-0.12,2,T376F +urn:mavedb:00000044-a-1#1811,NA,NA,p.Thr46Gly,-0.6,-0.61,1,T376G +urn:mavedb:00000044-a-1#1812,NA,NA,p.Thr46Gly,-0.62,-0.61,2,T376G +urn:mavedb:00000044-a-1#1813,NA,NA,p.Thr46His,0.03,-0.02,1,T376H +urn:mavedb:00000044-a-1#1814,NA,NA,p.Thr46His,-0.06,-0.02,2,T376H +urn:mavedb:00000044-a-1#1815,NA,NA,p.Thr46Ile,-0.06,-0.07,1,T376I +urn:mavedb:00000044-a-1#1816,NA,NA,p.Thr46Ile,-0.08,-0.07,2,T376I +urn:mavedb:00000044-a-1#1817,NA,NA,p.Thr46Lys,-0.03,-0.08,1,T376K +urn:mavedb:00000044-a-1#1818,NA,NA,p.Thr46Lys,-0.12,-0.08,2,T376K +urn:mavedb:00000044-a-1#1819,NA,NA,p.Thr46Leu,-0.03,-0.04,1,T376L +urn:mavedb:00000044-a-1#1820,NA,NA,p.Thr46Leu,-0.06,-0.04,2,T376L +urn:mavedb:00000044-a-1#1821,NA,NA,p.Thr46Met,-0.11,-0.06,1,T376M +urn:mavedb:00000044-a-1#1822,NA,NA,p.Thr46Met,-0.02,-0.06,2,T376M +urn:mavedb:00000044-a-1#1823,NA,NA,p.Thr46Asn,-0.22,-0.19,1,T376N +urn:mavedb:00000044-a-1#1824,NA,NA,p.Thr46Asn,-0.17,-0.19,2,T376N +urn:mavedb:00000044-a-1#1825,NA,NA,p.Thr46Pro,-0.83,-1.01,1,T376P +urn:mavedb:00000044-a-1#1826,NA,NA,p.Thr46Pro,-1.19,-1.01,2,T376P +urn:mavedb:00000044-a-1#1827,NA,NA,p.Thr46Gln,-0.01,-0.01,1,T376Q +urn:mavedb:00000044-a-1#1828,NA,NA,p.Thr46Gln,-0.02,-0.01,2,T376Q +urn:mavedb:00000044-a-1#1829,NA,NA,p.Thr46Arg,-0.07,-0.12,1,T376R +urn:mavedb:00000044-a-1#1830,NA,NA,p.Thr46Arg,-0.17,-0.12,2,T376R +urn:mavedb:00000044-a-1#1831,NA,NA,p.Thr46Ser,-0.08,-0.07,1,T376S +urn:mavedb:00000044-a-1#1832,NA,NA,p.Thr46Ser,-0.06,-0.07,2,T376S +urn:mavedb:00000044-a-1#1833,NA,NA,p.Thr46Val,-0.09,-0.06,1,T376V +urn:mavedb:00000044-a-1#1562,NA,NA,p.Asn40Ala,-0.05,-0.1,2,N370A +urn:mavedb:00000044-a-1#1563,NA,NA,p.Asn40Cys,-0.49,-0.48,1,N370C +urn:mavedb:00000044-a-1#1564,NA,NA,p.Asn40Cys,-0.46,-0.48,2,N370C +urn:mavedb:00000044-a-1#1565,NA,NA,p.Asn40Asp,-0.03,-0.04,1,N370D +urn:mavedb:00000044-a-1#1566,NA,NA,p.Asn40Asp,-0.04,-0.04,2,N370D +urn:mavedb:00000044-a-1#1567,NA,NA,p.Asn40Glu,0,0,1,N370E +urn:mavedb:00000044-a-1#1568,NA,NA,p.Asn40Glu,0,0,2,N370E +urn:mavedb:00000044-a-1#1569,NA,NA,p.Asn40Phe,-0.15,-0.23,1,N370F +urn:mavedb:00000044-a-1#1570,NA,NA,p.Asn40Phe,-0.31,-0.23,2,N370F +urn:mavedb:00000044-a-1#1571,NA,NA,p.Asn40Gly,-0.06,-0.04,1,N370G +urn:mavedb:00000044-a-1#1572,NA,NA,p.Asn40Gly,-0.01,-0.04,2,N370G +urn:mavedb:00000044-a-1#1573,NA,NA,p.Asn40His,0.02,-0.03,1,N370H +urn:mavedb:00000044-a-1#1639,NA,NA,p.Ser41*,NA,NA,1,S371 +urn:mavedb:00000044-a-1#1574,NA,NA,p.Asn40His,-0.07,-0.03,2,N370H +urn:mavedb:00000044-a-1#1575,NA,NA,p.Asn40Ile,-0.58,-0.58,1,N370I +urn:mavedb:00000044-a-1#1576,NA,NA,p.Asn40Ile,-0.58,-0.58,2,N370I +urn:mavedb:00000044-a-1#1577,NA,NA,p.Asn40Lys,-0.05,-0.04,1,N370K +urn:mavedb:00000044-a-1#1578,NA,NA,p.Asn40Lys,-0.02,-0.04,2,N370K +urn:mavedb:00000044-a-1#1579,NA,NA,p.Asn40Leu,-0.16,-0.17,1,N370L +urn:mavedb:00000044-a-1#1580,NA,NA,p.Asn40Leu,-0.19,-0.17,2,N370L +urn:mavedb:00000044-a-1#1581,NA,NA,p.Asn40Met,-0.12,-0.12,1,N370M +urn:mavedb:00000044-a-1#1582,NA,NA,p.Asn40Met,-0.11,-0.12,2,N370M +urn:mavedb:00000044-a-1#1583,NA,NA,p.Asn40Pro,-0.06,-0.12,1,N370P +urn:mavedb:00000044-a-1#1584,NA,NA,p.Asn40Pro,-0.18,-0.12,2,N370P +urn:mavedb:00000044-a-1#1585,NA,NA,p.Asn40Gln,0.05,0.02,1,N370Q +urn:mavedb:00000044-a-1#1586,NA,NA,p.Asn40Gln,-0.01,0.02,2,N370Q +urn:mavedb:00000044-a-1#1587,NA,NA,p.Asn40Arg,-0.01,-0.05,1,N370R +urn:mavedb:00000044-a-1#1588,NA,NA,p.Asn40Arg,-0.1,-0.05,2,N370R +urn:mavedb:00000044-a-1#1589,NA,NA,p.Asn40Ser,0.03,-0.02,1,N370S +urn:mavedb:00000044-a-1#1590,NA,NA,p.Asn40Ser,-0.07,-0.02,2,N370S +urn:mavedb:00000044-a-1#1591,NA,NA,p.Asn40Thr,0.03,-0.02,1,N370T +urn:mavedb:00000044-a-1#1592,NA,NA,p.Asn40Thr,-0.08,-0.02,2,N370T +urn:mavedb:00000044-a-1#1593,NA,NA,p.Asn40Val,-0.4,-0.45,1,N370V +urn:mavedb:00000044-a-1#1594,NA,NA,p.Asn40Val,-0.5,-0.45,2,N370V +urn:mavedb:00000044-a-1#1595,NA,NA,p.Asn40Trp,-0.41,-0.27,1,N370W +urn:mavedb:00000044-a-1#1596,NA,NA,p.Asn40Trp,-0.12,-0.27,2,N370W +urn:mavedb:00000044-a-1#1597,NA,NA,p.Asn40Tyr,-0.12,-0.14,1,N370Y +urn:mavedb:00000044-a-1#1598,NA,NA,p.Asn40Tyr,-0.16,-0.14,2,N370Y +urn:mavedb:00000044-a-1#1599,NA,NA,p.Asn40*,NA,NA,1,N370 +urn:mavedb:00000044-a-1#1600,NA,NA,p.Asn40*,NA,NA,2,N370 +urn:mavedb:00000044-a-1#1601,NA,NA,p.Ser41Ala,-0.07,-0.09,1,S371A +urn:mavedb:00000044-a-1#1602,NA,NA,p.Ser41Ala,-0.11,-0.09,2,S371A +urn:mavedb:00000044-a-1#1603,NA,NA,p.Ser41Cys,-0.2,-0.26,1,S371C +urn:mavedb:00000044-a-1#1604,NA,NA,p.Ser41Cys,-0.33,-0.26,2,S371C +urn:mavedb:00000044-a-1#1605,NA,NA,p.Ser41Asp,0.04,0.01,1,S371D +urn:mavedb:00000044-a-1#1606,NA,NA,p.Ser41Asp,-0.03,0.01,2,S371D +urn:mavedb:00000044-a-1#1607,NA,NA,p.Ser41Glu,-0.06,-0.05,1,S371E +urn:mavedb:00000044-a-1#1608,NA,NA,p.Ser41Glu,-0.04,-0.05,2,S371E +urn:mavedb:00000044-a-1#1609,NA,NA,p.Ser41Phe,-0.21,-0.19,1,S371F +urn:mavedb:00000044-a-1#1610,NA,NA,p.Ser41Phe,-0.17,-0.19,2,S371F +urn:mavedb:00000044-a-1#1611,NA,NA,p.Ser41Gly,-0.1,-0.1,1,S371G +urn:mavedb:00000044-a-1#1612,NA,NA,p.Ser41Gly,-0.1,-0.1,2,S371G +urn:mavedb:00000044-a-1#1613,NA,NA,p.Ser41His,-0.13,-0.12,1,S371H +urn:mavedb:00000044-a-1#1614,NA,NA,p.Ser41His,-0.11,-0.12,2,S371H +urn:mavedb:00000044-a-1#1615,NA,NA,p.Ser41Ile,-0.17,-0.17,1,S371I +urn:mavedb:00000044-a-1#1616,NA,NA,p.Ser41Ile,-0.17,-0.17,2,S371I +urn:mavedb:00000044-a-1#1617,NA,NA,p.Ser41Lys,-0.14,-0.13,1,S371K +urn:mavedb:00000044-a-1#1618,NA,NA,p.Ser41Lys,-0.12,-0.13,2,S371K +urn:mavedb:00000044-a-1#1619,NA,NA,p.Ser41Leu,-0.12,-0.14,1,S371L +urn:mavedb:00000044-a-1#1620,NA,NA,p.Ser41Leu,-0.16,-0.14,2,S371L +urn:mavedb:00000044-a-1#1621,NA,NA,p.Ser41Met,-0.16,-0.14,1,S371M +urn:mavedb:00000044-a-1#1622,NA,NA,p.Ser41Met,-0.13,-0.14,2,S371M +urn:mavedb:00000044-a-1#1623,NA,NA,p.Ser41Asn,-0.06,-0.05,1,S371N +urn:mavedb:00000044-a-1#1624,NA,NA,p.Ser41Asn,-0.05,-0.05,2,S371N +urn:mavedb:00000044-a-1#1625,NA,NA,p.Ser41Pro,-0.15,-0.16,1,S371P +urn:mavedb:00000044-a-1#1626,NA,NA,p.Ser41Pro,-0.17,-0.16,2,S371P +urn:mavedb:00000044-a-1#1627,NA,NA,p.Ser41Gln,-0.11,-0.1,1,S371Q +urn:mavedb:00000044-a-1#1628,NA,NA,p.Ser41Gln,-0.09,-0.1,2,S371Q +urn:mavedb:00000044-a-1#1629,NA,NA,p.Ser41Arg,-0.09,-0.11,1,S371R +urn:mavedb:00000044-a-1#1630,NA,NA,p.Ser41Arg,-0.13,-0.11,2,S371R +urn:mavedb:00000044-a-1#1631,NA,NA,p.Ser41Thr,-0.04,-0.03,1,S371T +urn:mavedb:00000044-a-1#1632,NA,NA,p.Ser41Thr,-0.02,-0.03,2,S371T +urn:mavedb:00000044-a-1#1633,NA,NA,p.Ser41Val,-0.16,-0.18,1,S371V +urn:mavedb:00000044-a-1#1634,NA,NA,p.Ser41Val,-0.2,-0.18,2,S371V +urn:mavedb:00000044-a-1#1635,NA,NA,p.Ser41Trp,-0.08,-0.11,1,S371W +urn:mavedb:00000044-a-1#1636,NA,NA,p.Ser41Trp,-0.14,-0.11,2,S371W +urn:mavedb:00000044-a-1#1637,NA,NA,p.Ser41Tyr,-0.09,-0.12,1,S371Y +urn:mavedb:00000044-a-1#1638,NA,NA,p.Ser41Tyr,-0.15,-0.12,2,S371Y +urn:mavedb:00000044-a-1#1641,NA,NA,p.Ala42Cys,-0.15,-0.18,1,A372C +urn:mavedb:00000044-a-1#1642,NA,NA,p.Ala42Cys,-0.22,-0.18,2,A372C +urn:mavedb:00000044-a-1#1643,NA,NA,p.Ala42Asp,-0.1,-0.1,1,A372D +urn:mavedb:00000044-a-1#1644,NA,NA,p.Ala42Asp,-0.09,-0.1,2,A372D +urn:mavedb:00000044-a-1#1645,NA,NA,p.Ala42Glu,0,0.01,1,A372E +urn:mavedb:00000044-a-1#1646,NA,NA,p.Ala42Glu,0.01,0.01,2,A372E +urn:mavedb:00000044-a-1#1647,NA,NA,p.Ala42Phe,-0.06,-0.09,1,A372F +urn:mavedb:00000044-a-1#1648,NA,NA,p.Ala42Phe,-0.12,-0.09,2,A372F +urn:mavedb:00000044-a-1#1649,NA,NA,p.Ala42Gly,0,0,1,A372G +urn:mavedb:00000044-a-1#1650,NA,NA,p.Ala42Gly,0.01,0,2,A372G +urn:mavedb:00000044-a-1#1651,NA,NA,p.Ala42His,-0.16,-0.13,1,A372H +urn:mavedb:00000044-a-1#1652,NA,NA,p.Ala42His,-0.11,-0.13,2,A372H +urn:mavedb:00000044-a-1#1653,NA,NA,p.Ala42Ile,-0.15,-0.13,1,A372I +urn:mavedb:00000044-a-1#1654,NA,NA,p.Ala42Ile,-0.12,-0.13,2,A372I +urn:mavedb:00000044-a-1#1655,NA,NA,p.Ala42Lys,-0.12,-0.05,1,A372K +urn:mavedb:00000044-a-1#1656,NA,NA,p.Ala42Lys,0.02,-0.05,2,A372K +urn:mavedb:00000044-a-1#1657,NA,NA,p.Ala42Leu,-0.19,-0.17,1,A372L +urn:mavedb:00000044-a-1#1658,NA,NA,p.Ala42Leu,-0.15,-0.17,2,A372L +urn:mavedb:00000044-a-1#1659,NA,NA,p.Ala42Met,-0.07,-0.04,1,A372M +urn:mavedb:00000044-a-1#1660,NA,NA,p.Ala42Met,0,-0.04,2,A372M +urn:mavedb:00000044-a-1#1661,NA,NA,p.Ala42Asn,-0.18,-0.2,1,A372N +urn:mavedb:00000044-a-1#1662,NA,NA,p.Ala42Asn,-0.23,-0.2,2,A372N +urn:mavedb:00000044-a-1#1663,NA,NA,p.Ala42Pro,-0.14,-0.14,1,A372P +urn:mavedb:00000044-a-1#1664,NA,NA,p.Ala42Pro,-0.14,-0.14,2,A372P +urn:mavedb:00000044-a-1#1665,NA,NA,p.Ala42Gln,-0.16,-0.08,1,A372Q +urn:mavedb:00000044-a-1#1666,NA,NA,p.Ala42Gln,0,-0.08,2,A372Q +urn:mavedb:00000044-a-1#1667,NA,NA,p.Ala42Arg,0.03,0.03,1,A372R +urn:mavedb:00000044-a-1#1668,NA,NA,p.Ala42Arg,0.03,0.03,2,A372R +urn:mavedb:00000044-a-1#1669,NA,NA,p.Ala42Ser,-0.22,-0.19,1,A372S +urn:mavedb:00000044-a-1#1670,NA,NA,p.Ala42Ser,-0.16,-0.19,2,A372S +urn:mavedb:00000044-a-1#1671,NA,NA,p.Ala42Thr,-0.13,-0.16,1,A372T +urn:mavedb:00000044-a-1#1672,NA,NA,p.Ala42Thr,-0.19,-0.16,2,A372T +urn:mavedb:00000044-a-1#1673,NA,NA,p.Ala42Val,-0.18,-0.12,1,A372V +urn:mavedb:00000044-a-1#1674,NA,NA,p.Ala42Val,-0.07,-0.12,2,A372V +urn:mavedb:00000044-a-1#1675,NA,NA,p.Ala42Trp,-0.14,-0.1,1,A372W +urn:mavedb:00000044-a-1#1676,NA,NA,p.Ala42Trp,-0.07,-0.1,2,A372W +urn:mavedb:00000044-a-1#1677,NA,NA,p.Ala42Tyr,-0.19,-0.18,1,A372Y +urn:mavedb:00000044-a-1#1678,NA,NA,p.Ala42Tyr,-0.17,-0.18,2,A372Y +urn:mavedb:00000044-a-1#1679,NA,NA,p.Ala42*,NA,NA,1,A372 +urn:mavedb:00000044-a-1#1681,NA,NA,p.Ser43Ala,-0.02,-0.03,1,S373A +urn:mavedb:00000044-a-1#1682,NA,NA,p.Ser43Ala,-0.03,-0.03,2,S373A +urn:mavedb:00000044-a-1#1683,NA,NA,p.Ser43Cys,-0.05,-0.07,1,S373C +urn:mavedb:00000044-a-1#1684,NA,NA,p.Ser43Cys,-0.09,-0.07,2,S373C +urn:mavedb:00000044-a-1#1685,NA,NA,p.Ser43Asp,-0.05,-0.04,1,S373D +urn:mavedb:00000044-a-1#1686,NA,NA,p.Ser43Asp,-0.02,-0.04,2,S373D +urn:mavedb:00000044-a-1#1687,NA,NA,p.Ser43Glu,-0.03,-0.01,1,S373E +urn:mavedb:00000044-a-1#1688,NA,NA,p.Ser43Glu,0.01,-0.01,2,S373E +urn:mavedb:00000044-a-1#1689,NA,NA,p.Ser43Phe,-0.02,-0.02,1,S373F +urn:mavedb:00000044-a-1#1690,NA,NA,p.Ser43Phe,-0.03,-0.02,2,S373F +urn:mavedb:00000044-a-1#1691,NA,NA,p.Ser43Gly,-0.02,-0.01,1,S373G +urn:mavedb:00000044-a-1#1692,NA,NA,p.Ser43Gly,0,-0.01,2,S373G +urn:mavedb:00000044-a-1#1693,NA,NA,p.Ser43His,-0.02,-0.01,1,S373H +urn:mavedb:00000044-a-1#1694,NA,NA,p.Ser43His,0.01,-0.01,2,S373H +urn:mavedb:00000044-a-1#1695,NA,NA,p.Ser43Ile,-0.04,-0.02,1,S373I +urn:mavedb:00000044-a-1#1696,NA,NA,p.Ser43Ile,-0.01,-0.02,2,S373I +urn:mavedb:00000044-a-1#1697,NA,NA,p.Ser43Lys,-0.06,-0.04,1,S373K +urn:mavedb:00000044-a-1#1698,NA,NA,p.Ser43Lys,-0.03,-0.04,2,S373K +urn:mavedb:00000044-a-1#1699,NA,NA,p.Ser43Leu,0,-0.02,1,S373L +urn:mavedb:00000044-a-1#1700,NA,NA,p.Ser43Leu,-0.04,-0.02,2,S373L +urn:mavedb:00000044-a-1#1701,NA,NA,p.Ser43Met,0,0.01,1,S373M +urn:mavedb:00000044-a-1#1702,NA,NA,p.Ser43Met,0.02,0.01,2,S373M +urn:mavedb:00000044-a-1#1703,NA,NA,p.Ser43Asn,-1.75,-1.06,1,S373N +urn:mavedb:00000044-a-1#1704,NA,NA,p.Ser43Asn,-0.38,-1.06,2,S373N +urn:mavedb:00000044-a-1#1705,NA,NA,p.Ser43Pro,-0.09,-0.08,1,S373P +urn:mavedb:00000044-a-1#1706,NA,NA,p.Ser43Pro,-0.07,-0.08,2,S373P +urn:mavedb:00000044-a-1#1707,NA,NA,p.Ser43Gln,0,0.05,1,S373Q +urn:mavedb:00000044-a-1#1708,NA,NA,p.Ser43Gln,0.1,0.05,2,S373Q +urn:mavedb:00000044-a-1#1709,NA,NA,p.Ser43Arg,-0.02,-0.01,1,S373R +urn:mavedb:00000044-a-1#1710,NA,NA,p.Ser43Arg,0,-0.01,2,S373R +urn:mavedb:00000044-a-1#1711,NA,NA,p.Ser43Thr,0,0,1,S373T +urn:mavedb:00000044-a-1#1712,NA,NA,p.Ser43Thr,0,0,2,S373T +urn:mavedb:00000044-a-1#1713,NA,NA,p.Ser43Val,-0.07,-0.07,1,S373V +urn:mavedb:00000044-a-1#1714,NA,NA,p.Ser43Val,-0.07,-0.07,2,S373V +urn:mavedb:00000044-a-1#1715,NA,NA,p.Ser43Trp,-0.02,-0.04,1,S373W +urn:mavedb:00000044-a-1#1716,NA,NA,p.Ser43Trp,-0.07,-0.04,2,S373W +urn:mavedb:00000044-a-1#1717,NA,NA,p.Ser43Tyr,-0.01,-0.01,1,S373Y +urn:mavedb:00000044-a-1#1718,NA,NA,p.Ser43Tyr,0,-0.01,2,S373Y +urn:mavedb:00000044-a-1#1719,NA,NA,p.Ser43*,NA,NA,1,S373 +urn:mavedb:00000044-a-1#1720,NA,NA,p.Ser43*,NA,NA,2,S373 +urn:mavedb:00000044-a-1#1721,NA,NA,p.Phe44Ala,-0.22,-0.29,1,F374A +urn:mavedb:00000044-a-1#1722,NA,NA,p.Phe44Ala,-0.36,-0.29,2,F374A +urn:mavedb:00000044-a-1#1723,NA,NA,p.Phe44Cys,-0.62,-0.61,1,F374C +urn:mavedb:00000044-a-1#1724,NA,NA,p.Phe44Cys,-0.61,-0.61,2,F374C +urn:mavedb:00000044-a-1#1725,NA,NA,p.Phe44Asp,-0.22,-0.24,1,F374D +urn:mavedb:00000044-a-1#1726,NA,NA,p.Phe44Asp,-0.26,-0.24,2,F374D +urn:mavedb:00000044-a-1#1727,NA,NA,p.Phe44Glu,-0.32,-0.32,1,F374E +urn:mavedb:00000044-a-1#1728,NA,NA,p.Phe44Glu,-0.32,-0.32,2,F374E +urn:mavedb:00000044-a-1#1729,NA,NA,p.Phe44Gly,-0.2,-0.24,1,F374G +urn:mavedb:00000044-a-1#1730,NA,NA,p.Phe44Gly,-0.29,-0.24,2,F374G +urn:mavedb:00000044-a-1#1731,NA,NA,p.Phe44His,-0.26,-0.24,1,F374H +urn:mavedb:00000044-a-1#1732,NA,NA,p.Phe44His,-0.22,-0.24,2,F374H +urn:mavedb:00000044-a-1#1733,NA,NA,p.Phe44Ile,-0.13,-0.15,1,F374I +urn:mavedb:00000044-a-1#1734,NA,NA,p.Phe44Ile,-0.17,-0.15,2,F374I +urn:mavedb:00000044-a-1#1735,NA,NA,p.Phe44Lys,-0.21,-0.28,1,F374K +urn:mavedb:00000044-a-1#1736,NA,NA,p.Phe44Lys,-0.34,-0.28,2,F374K +urn:mavedb:00000044-a-1#1737,NA,NA,p.Phe44Leu,-0.23,-0.25,1,F374L +urn:mavedb:00000044-a-1#1738,NA,NA,p.Phe44Leu,-0.28,-0.25,2,F374L +urn:mavedb:00000044-a-1#1739,NA,NA,p.Phe44Met,-0.14,-0.22,1,F374M +urn:mavedb:00000044-a-1#1740,NA,NA,p.Phe44Met,-0.3,-0.22,2,F374M +urn:mavedb:00000044-a-1#1741,NA,NA,p.Phe44Asn,-0.85,-0.92,1,F374N +urn:mavedb:00000044-a-1#1742,NA,NA,p.Phe44Asn,-1,-0.92,2,F374N +urn:mavedb:00000044-a-1#1743,NA,NA,p.Phe44Pro,-0.28,-0.33,1,F374P +urn:mavedb:00000044-a-1#1744,NA,NA,p.Phe44Pro,-0.37,-0.33,2,F374P +urn:mavedb:00000044-a-1#1745,NA,NA,p.Phe44Gln,-0.29,-0.32,1,F374Q +urn:mavedb:00000044-a-1#1746,NA,NA,p.Phe44Gln,-0.35,-0.32,2,F374Q +urn:mavedb:00000044-a-1#1747,NA,NA,p.Phe44Arg,-0.34,-0.36,1,F374R +urn:mavedb:00000044-a-1#1748,NA,NA,p.Phe44Arg,-0.39,-0.36,2,F374R +urn:mavedb:00000044-a-1#1749,NA,NA,p.Phe44Ser,-0.33,-0.35,1,F374S +urn:mavedb:00000044-a-1#1750,NA,NA,p.Phe44Ser,-0.38,-0.35,2,F374S +urn:mavedb:00000044-a-1#1751,NA,NA,p.Phe44Thr,-0.29,-0.32,1,F374T +urn:mavedb:00000044-a-1#1752,NA,NA,p.Phe44Thr,-0.34,-0.32,2,F374T +urn:mavedb:00000044-a-1#1753,NA,NA,p.Phe44Val,-0.34,-0.32,1,F374V +urn:mavedb:00000044-a-1#1754,NA,NA,p.Phe44Val,-0.3,-0.32,2,F374V +urn:mavedb:00000044-a-1#1755,NA,NA,p.Phe44Trp,0.01,-0.02,1,F374W +urn:mavedb:00000044-a-1#1756,NA,NA,p.Phe44Trp,-0.04,-0.02,2,F374W +urn:mavedb:00000044-a-1#1757,NA,NA,p.Phe44Tyr,-0.07,-0.06,1,F374Y +urn:mavedb:00000044-a-1#1758,NA,NA,p.Phe44Tyr,-0.05,-0.06,2,F374Y +urn:mavedb:00000044-a-1#1759,NA,NA,p.Phe44*,NA,NA,1,F374 +urn:mavedb:00000044-a-1#1760,NA,NA,p.Phe44*,NA,NA,2,F374 +urn:mavedb:00000044-a-1#1761,NA,NA,p.Ser45Ala,-0.14,-0.13,1,S375A +urn:mavedb:00000044-a-1#1762,NA,NA,p.Ser45Ala,-0.12,-0.13,2,S375A +urn:mavedb:00000044-a-1#1968,NA,NA,p.Tyr50Glu,-1.39,-1.8,2,Y380E +urn:mavedb:00000044-a-1#1834,NA,NA,p.Thr46Val,-0.02,-0.06,2,T376V +urn:mavedb:00000044-a-1#1835,NA,NA,p.Thr46Trp,-0.04,-0.09,1,T376W +urn:mavedb:00000044-a-1#1836,NA,NA,p.Thr46Trp,-0.13,-0.09,2,T376W +urn:mavedb:00000044-a-1#1837,NA,NA,p.Thr46Tyr,-0.02,-0.09,1,T376Y +urn:mavedb:00000044-a-1#1838,NA,NA,p.Thr46Tyr,-0.16,-0.09,2,T376Y +urn:mavedb:00000044-a-1#1839,NA,NA,p.Thr46*,NA,NA,1,T376 +urn:mavedb:00000044-a-1#1840,NA,NA,p.Thr46*,NA,NA,2,T376 +urn:mavedb:00000044-a-1#1841,NA,NA,p.Phe47Ala,-0.54,-0.59,1,F377A +urn:mavedb:00000044-a-1#1842,NA,NA,p.Phe47Ala,-0.64,-0.59,2,F377A +urn:mavedb:00000044-a-1#1843,NA,NA,p.Phe47Cys,-0.36,-0.4,1,F377C +urn:mavedb:00000044-a-1#1844,NA,NA,p.Phe47Cys,-0.44,-0.4,2,F377C +urn:mavedb:00000044-a-1#1845,NA,NA,p.Phe47Asp,-3.48,-4.01,1,F377D +urn:mavedb:00000044-a-1#1846,NA,NA,p.Phe47Asp,-4.55,-4.01,2,F377D +urn:mavedb:00000044-a-1#1847,NA,NA,p.Phe47Glu,-2.14,-2.12,1,F377E +urn:mavedb:00000044-a-1#1848,NA,NA,p.Phe47Glu,-2.1,-2.12,2,F377E +urn:mavedb:00000044-a-1#1849,NA,NA,p.Phe47Gly,-1.49,-1.87,1,F377G +urn:mavedb:00000044-a-1#1850,NA,NA,p.Phe47Gly,-2.25,-1.87,2,F377G +urn:mavedb:00000044-a-1#1851,NA,NA,p.Phe47His,-0.64,-0.62,1,F377H +urn:mavedb:00000044-a-1#1852,NA,NA,p.Phe47His,-0.6,-0.62,2,F377H +urn:mavedb:00000044-a-1#1853,NA,NA,p.Phe47Ile,-0.18,-0.16,1,F377I +urn:mavedb:00000044-a-1#1854,NA,NA,p.Phe47Ile,-0.14,-0.16,2,F377I +urn:mavedb:00000044-a-1#1855,NA,NA,p.Phe47Lys,-0.7,-0.71,1,F377K +urn:mavedb:00000044-a-1#1856,NA,NA,p.Phe47Lys,-0.72,-0.71,2,F377K +urn:mavedb:00000044-a-1#1857,NA,NA,p.Phe47Leu,-0.15,-0.2,1,F377L +urn:mavedb:00000044-a-1#1858,NA,NA,p.Phe47Leu,-0.26,-0.2,2,F377L +urn:mavedb:00000044-a-1#1859,NA,NA,p.Phe47Met,-0.12,-0.7,1,F377M +urn:mavedb:00000044-a-1#1860,NA,NA,p.Phe47Met,-1.27,-0.7,2,F377M +urn:mavedb:00000044-a-1#1861,NA,NA,p.Phe47Asn,-0.8,-0.84,1,F377N +urn:mavedb:00000044-a-1#1862,NA,NA,p.Phe47Asn,-0.89,-0.84,2,F377N +urn:mavedb:00000044-a-1#1863,NA,NA,p.Phe47Pro,0,-0.81,1,F377P +urn:mavedb:00000044-a-1#1864,NA,NA,p.Phe47Pro,-1.62,-0.81,2,F377P +urn:mavedb:00000044-a-1#1865,NA,NA,p.Phe47Gln,-1.76,-1.37,1,F377Q +urn:mavedb:00000044-a-1#1866,NA,NA,p.Phe47Gln,-0.98,-1.37,2,F377Q +urn:mavedb:00000044-a-1#1867,NA,NA,p.Phe47Arg,-0.57,-0.64,1,F377R +urn:mavedb:00000044-a-1#1868,NA,NA,p.Phe47Arg,-0.71,-0.64,2,F377R +urn:mavedb:00000044-a-1#1869,NA,NA,p.Phe47Ser,-0.82,-0.83,1,F377S +urn:mavedb:00000044-a-1#1870,NA,NA,p.Phe47Ser,-0.84,-0.83,2,F377S +urn:mavedb:00000044-a-1#1875,NA,NA,p.Phe47Trp,-0.05,-0.07,1,F377W +urn:mavedb:00000044-a-1#1876,NA,NA,p.Phe47Trp,-0.09,-0.07,2,F377W +urn:mavedb:00000044-a-1#1877,NA,NA,p.Phe47Tyr,-0.18,-0.24,1,F377Y +urn:mavedb:00000044-a-1#1878,NA,NA,p.Phe47Tyr,-0.31,-0.24,2,F377Y +urn:mavedb:00000044-a-1#1881,NA,NA,p.Lys48Ala,-0.07,-0.1,1,K378A +urn:mavedb:00000044-a-1#1882,NA,NA,p.Lys48Ala,-0.12,-0.1,2,K378A +urn:mavedb:00000044-a-1#1883,NA,NA,p.Lys48Cys,-0.05,-0.14,1,K378C +urn:mavedb:00000044-a-1#1884,NA,NA,p.Lys48Cys,-0.23,-0.14,2,K378C +urn:mavedb:00000044-a-1#1871,NA,NA,p.Phe47Thr,-0.44,-0.44,1,F377T +urn:mavedb:00000044-a-1#1872,NA,NA,p.Phe47Thr,-0.45,-0.44,2,F377T +urn:mavedb:00000044-a-1#1873,NA,NA,p.Phe47Val,-0.12,-0.15,1,F377V +urn:mavedb:00000044-a-1#1874,NA,NA,p.Phe47Val,-0.18,-0.15,2,F377V +urn:mavedb:00000044-a-1#1885,NA,NA,p.Lys48Asp,-0.02,-0.03,1,K378D +urn:mavedb:00000044-a-1#1886,NA,NA,p.Lys48Asp,-0.05,-0.03,2,K378D +urn:mavedb:00000044-a-1#1887,NA,NA,p.Lys48Glu,-0.02,-0.04,1,K378E +urn:mavedb:00000044-a-1#1888,NA,NA,p.Lys48Glu,-0.05,-0.04,2,K378E +urn:mavedb:00000044-a-1#1889,NA,NA,p.Lys48Phe,-0.48,-0.5,1,K378F +urn:mavedb:00000044-a-1#1890,NA,NA,p.Lys48Phe,-0.53,-0.5,2,K378F +urn:mavedb:00000044-a-1#1891,NA,NA,p.Lys48Gly,-0.85,-0.89,1,K378G +urn:mavedb:00000044-a-1#1892,NA,NA,p.Lys48Gly,-0.94,-0.89,2,K378G +urn:mavedb:00000044-a-1#1893,NA,NA,p.Lys48His,-0.2,-0.17,1,K378H +urn:mavedb:00000044-a-1#1894,NA,NA,p.Lys48His,-0.14,-0.17,2,K378H +urn:mavedb:00000044-a-1#1895,NA,NA,p.Lys48Ile,-0.11,-0.11,1,K378I +urn:mavedb:00000044-a-1#1896,NA,NA,p.Lys48Ile,-0.11,-0.11,2,K378I +urn:mavedb:00000044-a-1#1897,NA,NA,p.Lys48Leu,-0.04,-0.06,1,K378L +urn:mavedb:00000044-a-1#1898,NA,NA,p.Lys48Leu,-0.08,-0.06,2,K378L +urn:mavedb:00000044-a-1#1899,NA,NA,p.Lys48Met,-0.13,-0.13,1,K378M +urn:mavedb:00000044-a-1#1900,NA,NA,p.Lys48Met,-0.12,-0.13,2,K378M +urn:mavedb:00000044-a-1#1901,NA,NA,p.Lys48Asn,0.01,-0.02,1,K378N +urn:mavedb:00000044-a-1#1902,NA,NA,p.Lys48Asn,-0.05,-0.02,2,K378N +urn:mavedb:00000044-a-1#1903,NA,NA,p.Lys48Pro,-3.2,-4.02,1,K378P +urn:mavedb:00000044-a-1#1904,NA,NA,p.Lys48Pro,-4.84,-4.02,2,K378P +urn:mavedb:00000044-a-1#1905,NA,NA,p.Lys48Gln,0.01,-0.01,1,K378Q +urn:mavedb:00000044-a-1#1906,NA,NA,p.Lys48Gln,-0.03,-0.01,2,K378Q +urn:mavedb:00000044-a-1#1921,NA,NA,p.Cys49Ala,-1.08,-1.44,1,C379A +urn:mavedb:00000044-a-1#1907,NA,NA,p.Lys48Arg,0.03,0.08,1,K378R +urn:mavedb:00000044-a-1#1908,NA,NA,p.Lys48Arg,0.13,0.08,2,K378R +urn:mavedb:00000044-a-1#1909,NA,NA,p.Lys48Ser,-0.11,-0.11,1,K378S +urn:mavedb:00000044-a-1#1910,NA,NA,p.Lys48Ser,-0.12,-0.11,2,K378S +urn:mavedb:00000044-a-1#1911,NA,NA,p.Lys48Thr,-0.05,-0.16,1,K378T +urn:mavedb:00000044-a-1#1912,NA,NA,p.Lys48Thr,-0.28,-0.16,2,K378T +urn:mavedb:00000044-a-1#1913,NA,NA,p.Lys48Val,-0.1,-0.09,1,K378V +urn:mavedb:00000044-a-1#1964,NA,NA,p.Tyr50Cys,-1.29,-1.37,2,Y380C +urn:mavedb:00000044-a-1#1965,NA,NA,p.Tyr50Asp,-4.18,-3.05,1,Y380D +urn:mavedb:00000044-a-1#1955,NA,NA,p.Cys49Trp,-0.47,-0.46,1,C379W +urn:mavedb:00000044-a-1#1956,NA,NA,p.Cys49Trp,-0.44,-0.46,2,C379W +urn:mavedb:00000044-a-1#1966,NA,NA,p.Tyr50Asp,-1.92,-3.05,2,Y380D +urn:mavedb:00000044-a-1#1948,NA,NA,p.Cys49Arg,-4.48,-4.12,2,C379R +urn:mavedb:00000044-a-1#1949,NA,NA,p.Cys49Ser,-1.67,-1.61,1,C379S +urn:mavedb:00000044-a-1#1950,NA,NA,p.Cys49Ser,-1.54,-1.61,2,C379S +urn:mavedb:00000044-a-1#1951,NA,NA,p.Cys49Thr,-0.78,-0.9,1,C379T +urn:mavedb:00000044-a-1#1952,NA,NA,p.Cys49Thr,-1.02,-0.9,2,C379T +urn:mavedb:00000044-a-1#1953,NA,NA,p.Cys49Val,-0.8,-0.84,1,C379V +urn:mavedb:00000044-a-1#1954,NA,NA,p.Cys49Val,-0.88,-0.84,2,C379V +urn:mavedb:00000044-a-1#1957,NA,NA,p.Cys49Tyr,-1.01,-1.05,1,C379Y +urn:mavedb:00000044-a-1#1958,NA,NA,p.Cys49Tyr,-1.09,-1.05,2,C379Y +urn:mavedb:00000044-a-1#1959,NA,NA,p.Cys49*,NA,NA,1,C379 +urn:mavedb:00000044-a-1#1960,NA,NA,p.Cys49*,NA,NA,2,C379 +urn:mavedb:00000044-a-1#1961,NA,NA,p.Tyr50Ala,-2.39,-1.9,1,Y380A +urn:mavedb:00000044-a-1#1962,NA,NA,p.Tyr50Ala,-1.4,-1.9,2,Y380A +urn:mavedb:00000044-a-1#1963,NA,NA,p.Tyr50Cys,-1.45,-1.37,1,Y380C +urn:mavedb:00000044-a-1#1969,NA,NA,p.Tyr50Phe,0.02,-0.04,1,Y380F +urn:mavedb:00000044-a-1#1970,NA,NA,p.Tyr50Phe,-0.1,-0.04,2,Y380F +urn:mavedb:00000044-a-1#1971,NA,NA,p.Tyr50Gly,-4.2,-4.12,1,Y380G +urn:mavedb:00000044-a-1#1972,NA,NA,p.Tyr50Gly,-4.03,-4.12,2,Y380G +urn:mavedb:00000044-a-1#1973,NA,NA,p.Tyr50His,-0.5,-0.53,1,Y380H +urn:mavedb:00000044-a-1#1974,NA,NA,p.Tyr50His,-0.57,-0.53,2,Y380H +urn:mavedb:00000044-a-1#1975,NA,NA,p.Tyr50Ile,-0.6,-0.73,1,Y380I +urn:mavedb:00000044-a-1#1976,NA,NA,p.Tyr50Ile,-0.86,-0.73,2,Y380I +urn:mavedb:00000044-a-1#1977,NA,NA,p.Tyr50Lys,-1.37,-1.53,1,Y380K +urn:mavedb:00000044-a-1#1978,NA,NA,p.Tyr50Lys,-1.69,-1.53,2,Y380K +urn:mavedb:00000044-a-1#1979,NA,NA,p.Tyr50Leu,-1.33,-1.53,1,Y380L +urn:mavedb:00000044-a-1#1980,NA,NA,p.Tyr50Leu,-1.72,-1.53,2,Y380L +urn:mavedb:00000044-a-1#1981,NA,NA,p.Tyr50Met,-1.01,-1.07,1,Y380M +urn:mavedb:00000044-a-1#1982,NA,NA,p.Tyr50Met,-1.13,-1.07,2,Y380M +urn:mavedb:00000044-a-1#1983,NA,NA,p.Tyr50Asn,-1.55,-1.49,1,Y380N +urn:mavedb:00000044-a-1#1984,NA,NA,p.Tyr50Asn,-1.44,-1.49,2,Y380N +urn:mavedb:00000044-a-1#1985,NA,NA,p.Tyr50Pro,-4.76,-4.8,1,Y380P +urn:mavedb:00000044-a-1#1986,NA,NA,p.Tyr50Pro,-4.84,-4.8,2,Y380P +urn:mavedb:00000044-a-1#1987,NA,NA,p.Tyr50Gln,-1.29,-1.42,1,Y380Q +urn:mavedb:00000044-a-1#1988,NA,NA,p.Tyr50Gln,-1.54,-1.42,2,Y380Q +urn:mavedb:00000044-a-1#1989,NA,NA,p.Tyr50Arg,-1.28,-1.34,1,Y380R +urn:mavedb:00000044-a-1#1990,NA,NA,p.Tyr50Arg,-1.39,-1.34,2,Y380R +urn:mavedb:00000044-a-1#1991,NA,NA,p.Tyr50Ser,-1.09,-1.17,1,Y380S +urn:mavedb:00000044-a-1#1992,NA,NA,p.Tyr50Ser,-1.24,-1.17,2,Y380S +urn:mavedb:00000044-a-1#1993,NA,NA,p.Tyr50Thr,-0.6,-0.77,1,Y380T +urn:mavedb:00000044-a-1#1994,NA,NA,p.Tyr50Thr,-0.95,-0.77,2,Y380T +urn:mavedb:00000044-a-1#1995,NA,NA,p.Tyr50Val,-0.82,-0.95,1,Y380V +urn:mavedb:00000044-a-1#1996,NA,NA,p.Tyr50Val,-1.09,-0.95,2,Y380V +urn:mavedb:00000044-a-1#1997,NA,NA,p.Tyr50Trp,-0.07,-0.08,1,Y380W +urn:mavedb:00000044-a-1#1998,NA,NA,p.Tyr50Trp,-0.08,-0.08,2,Y380W +urn:mavedb:00000044-a-1#1999,NA,NA,p.Tyr50*,NA,NA,1,Y380 +urn:mavedb:00000044-a-1#2000,NA,NA,p.Tyr50*,NA,NA,2,Y380 +urn:mavedb:00000044-a-1#2001,NA,NA,p.Gly51Ala,-0.47,-0.52,1,G381A +urn:mavedb:00000044-a-1#2002,NA,NA,p.Gly51Ala,-0.57,-0.52,2,G381A +urn:mavedb:00000044-a-1#2003,NA,NA,p.Gly51Cys,-0.7,-0.7,1,G381C +urn:mavedb:00000044-a-1#2004,NA,NA,p.Gly51Cys,-0.7,-0.7,2,G381C +urn:mavedb:00000044-a-1#2005,NA,NA,p.Gly51Asp,-0.52,-0.55,1,G381D +urn:mavedb:00000044-a-1#2006,NA,NA,p.Gly51Asp,-0.57,-0.55,2,G381D +urn:mavedb:00000044-a-1#2007,NA,NA,p.Gly51Glu,-0.55,-0.54,1,G381E +urn:mavedb:00000044-a-1#2008,NA,NA,p.Gly51Glu,-0.53,-0.54,2,G381E +urn:mavedb:00000044-a-1#2009,NA,NA,p.Gly51Phe,-0.77,-0.81,1,G381F +urn:mavedb:00000044-a-1#2010,NA,NA,p.Gly51Phe,-0.84,-0.81,2,G381F +urn:mavedb:00000044-a-1#2011,NA,NA,p.Gly51His,-0.14,-0.15,1,G381H +urn:mavedb:00000044-a-1#2012,NA,NA,p.Gly51His,-0.16,-0.15,2,G381H +urn:mavedb:00000044-a-1#2013,NA,NA,p.Gly51Ile,-0.8,-0.86,1,G381I +urn:mavedb:00000044-a-1#2014,NA,NA,p.Gly51Ile,-0.91,-0.86,2,G381I +urn:mavedb:00000044-a-1#2015,NA,NA,p.Gly51Lys,-0.02,-0.07,1,G381K +urn:mavedb:00000044-a-1#2016,NA,NA,p.Gly51Lys,-0.12,-0.07,2,G381K +urn:mavedb:00000044-a-1#2017,NA,NA,p.Gly51Leu,-0.58,-0.65,1,G381L +urn:mavedb:00000044-a-1#2018,NA,NA,p.Gly51Leu,-0.72,-0.65,2,G381L +urn:mavedb:00000044-a-1#2019,NA,NA,p.Gly51Met,-0.54,-0.58,1,G381M +urn:mavedb:00000044-a-1#2020,NA,NA,p.Gly51Met,-0.62,-0.58,2,G381M +urn:mavedb:00000044-a-1#2052,NA,NA,p.Val52Gly,-0.68,-0.68,2,V382G +urn:mavedb:00000044-a-1#2021,NA,NA,p.Gly51Asn,-0.02,-0.02,1,G381N +urn:mavedb:00000044-a-1#2022,NA,NA,p.Gly51Asn,-0.01,-0.02,2,G381N +urn:mavedb:00000044-a-1#2023,NA,NA,p.Gly51Pro,-0.92,-0.97,1,G381P +urn:mavedb:00000044-a-1#2024,NA,NA,p.Gly51Pro,-1.01,-0.97,2,G381P +urn:mavedb:00000044-a-1#2025,NA,NA,p.Gly51Gln,-0.11,-0.12,1,G381Q +urn:mavedb:00000044-a-1#2026,NA,NA,p.Gly51Gln,-0.13,-0.12,2,G381Q +urn:mavedb:00000044-a-1#2027,NA,NA,p.Gly51Arg,0,-0.03,1,G381R +urn:mavedb:00000044-a-1#2028,NA,NA,p.Gly51Arg,-0.05,-0.03,2,G381R +urn:mavedb:00000044-a-1#2029,NA,NA,p.Gly51Ser,-0.27,-0.27,1,G381S +urn:mavedb:00000044-a-1#2030,NA,NA,p.Gly51Ser,-0.28,-0.27,2,G381S +urn:mavedb:00000044-a-1#2031,NA,NA,p.Gly51Thr,-0.52,-0.53,1,G381T +urn:mavedb:00000044-a-1#2032,NA,NA,p.Gly51Thr,-0.55,-0.53,2,G381T +urn:mavedb:00000044-a-1#2033,NA,NA,p.Gly51Val,-0.67,-0.7,1,G381V +urn:mavedb:00000044-a-1#2034,NA,NA,p.Gly51Val,-0.74,-0.7,2,G381V +urn:mavedb:00000044-a-1#2035,NA,NA,p.Gly51Trp,-0.7,-0.87,1,G381W +urn:mavedb:00000044-a-1#2036,NA,NA,p.Gly51Trp,-1.04,-0.87,2,G381W +urn:mavedb:00000044-a-1#2037,NA,NA,p.Gly51Tyr,-0.74,-0.79,1,G381Y +urn:mavedb:00000044-a-1#2038,NA,NA,p.Gly51Tyr,-0.83,-0.79,2,G381Y +urn:mavedb:00000044-a-1#2039,NA,NA,p.Gly51*,NA,NA,1,G381 +urn:mavedb:00000044-a-1#2040,NA,NA,p.Gly51*,NA,NA,2,G381 +urn:mavedb:00000044-a-1#2041,NA,NA,p.Val52Ala,-0.25,-0.26,1,V382A +urn:mavedb:00000044-a-1#2042,NA,NA,p.Val52Ala,-0.26,-0.26,2,V382A +urn:mavedb:00000044-a-1#2043,NA,NA,p.Val52Cys,-0.09,-0.06,1,V382C +urn:mavedb:00000044-a-1#2044,NA,NA,p.Val52Cys,-0.04,-0.06,2,V382C +urn:mavedb:00000044-a-1#2045,NA,NA,p.Val52Asp,-0.56,-0.62,1,V382D +urn:mavedb:00000044-a-1#2046,NA,NA,p.Val52Asp,-0.68,-0.62,2,V382D +urn:mavedb:00000044-a-1#2047,NA,NA,p.Val52Glu,-0.44,-0.52,1,V382E +urn:mavedb:00000044-a-1#2048,NA,NA,p.Val52Glu,-0.61,-0.52,2,V382E +urn:mavedb:00000044-a-1#2049,NA,NA,p.Val52Phe,-0.01,-0.01,1,V382F +urn:mavedb:00000044-a-1#2050,NA,NA,p.Val52Phe,-0.01,-0.01,2,V382F +urn:mavedb:00000044-a-1#2051,NA,NA,p.Val52Gly,-0.69,-0.68,1,V382G +urn:mavedb:00000044-a-1#2053,NA,NA,p.Val52His,-0.35,-0.32,1,V382H +urn:mavedb:00000044-a-1#2054,NA,NA,p.Val52His,-0.28,-0.32,2,V382H +urn:mavedb:00000044-a-1#2055,NA,NA,p.Val52Ile,0.05,0,1,V382I +urn:mavedb:00000044-a-1#2056,NA,NA,p.Val52Ile,-0.05,0,2,V382I +urn:mavedb:00000044-a-1#2057,NA,NA,p.Val52Lys,-0.47,-0.52,1,V382K +urn:mavedb:00000044-a-1#2095,NA,NA,p.Ser53Ile,0.11,0.05,1,S383I +urn:mavedb:00000044-a-1#2096,NA,NA,p.Ser53Ile,-0.01,0.05,2,S383I +urn:mavedb:00000044-a-1#2097,NA,NA,p.Ser53Lys,0,0.01,1,S383K +urn:mavedb:00000044-a-1#2098,NA,NA,p.Ser53Lys,0.03,0.01,2,S383K +urn:mavedb:00000044-a-1#2099,NA,NA,p.Ser53Leu,-0.07,-0.07,1,S383L +urn:mavedb:00000044-a-1#2102,NA,NA,p.Ser53Met,-0.06,-0.04,2,S383M +urn:mavedb:00000044-a-1#2058,NA,NA,p.Val52Lys,-0.58,-0.52,2,V382K +urn:mavedb:00000044-a-1#2059,NA,NA,p.Val52Leu,-0.05,-0.05,1,V382L +urn:mavedb:00000044-a-1#2122,NA,NA,p.Pro54Ala,0.02,0.01,2,P384A +urn:mavedb:00000044-a-1#2060,NA,NA,p.Val52Leu,-0.04,-0.05,2,V382L +urn:mavedb:00000044-a-1#2123,NA,NA,p.Pro54Cys,-0.14,-0.16,1,P384C +urn:mavedb:00000044-a-1#2124,NA,NA,p.Pro54Cys,-0.19,-0.16,2,P384C +urn:mavedb:00000044-a-1#2061,NA,NA,p.Val52Met,-0.12,-0.14,1,V382M +urn:mavedb:00000044-a-1#2103,NA,NA,p.Ser53Asn,0,0,1,S383N +urn:mavedb:00000044-a-1#2125,NA,NA,p.Pro54Asp,-0.1,-0.14,1,P384D +urn:mavedb:00000044-a-1#2062,NA,NA,p.Val52Met,-0.16,-0.14,2,V382M +urn:mavedb:00000044-a-1#2164,NA,NA,p.Thr55Cys,-0.32,-0.26,2,T385C +urn:mavedb:00000044-a-1#2165,NA,NA,p.Thr55Asp,-0.03,-0.01,1,T385D +urn:mavedb:00000044-a-1#2166,NA,NA,p.Thr55Asp,0.02,-0.01,2,T385D +urn:mavedb:00000044-a-1#2167,NA,NA,p.Thr55Glu,0.07,0.06,1,T385E +urn:mavedb:00000044-a-1#2168,NA,NA,p.Thr55Glu,0.05,0.06,2,T385E +urn:mavedb:00000044-a-1#2131,NA,NA,p.Pro54Gly,-0.21,-0.17,1,P384G +urn:mavedb:00000044-a-1#2169,NA,NA,p.Thr55Phe,0,-0.01,1,T385F +urn:mavedb:00000044-a-1#2132,NA,NA,p.Pro54Gly,-0.13,-0.17,2,P384G +urn:mavedb:00000044-a-1#2170,NA,NA,p.Thr55Phe,-0.02,-0.01,2,T385F +urn:mavedb:00000044-a-1#2133,NA,NA,p.Pro54His,-0.08,-0.03,1,P384H +urn:mavedb:00000044-a-1#2171,NA,NA,p.Thr55Gly,0,-0.02,1,T385G +urn:mavedb:00000044-a-1#2172,NA,NA,p.Thr55Gly,-0.04,-0.02,2,T385G +urn:mavedb:00000044-a-1#2135,NA,NA,p.Pro54Ile,0.02,0.02,1,P384I +urn:mavedb:00000044-a-1#2142,NA,NA,p.Pro54Met,-0.05,-0.02,2,P384M +urn:mavedb:00000044-a-1#2143,NA,NA,p.Pro54Asn,-0.12,-0.18,1,P384N +urn:mavedb:00000044-a-1#2173,NA,NA,p.Thr55His,0.05,0.01,1,T385H +urn:mavedb:00000044-a-1#2174,NA,NA,p.Thr55His,-0.03,0.01,2,T385H +urn:mavedb:00000044-a-1#2136,NA,NA,p.Pro54Ile,0.02,0.02,2,P384I +urn:mavedb:00000044-a-1#2175,NA,NA,p.Thr55Ile,-0.03,-0.04,1,T385I +urn:mavedb:00000044-a-1#2176,NA,NA,p.Thr55Ile,-0.05,-0.04,2,T385I +urn:mavedb:00000044-a-1#2137,NA,NA,p.Pro54Lys,0.04,0.04,1,P384K +urn:mavedb:00000044-a-1#2138,NA,NA,p.Pro54Lys,0.03,0.04,2,P384K +urn:mavedb:00000044-a-1#2139,NA,NA,p.Pro54Leu,-0.02,0.01,1,P384L +urn:mavedb:00000044-a-1#2140,NA,NA,p.Pro54Leu,0.04,0.01,2,P384L +urn:mavedb:00000044-a-1#2141,NA,NA,p.Pro54Met,0,-0.02,1,P384M +urn:mavedb:00000044-a-1#2146,NA,NA,p.Pro54Gln,-0.03,0.03,2,P384Q +urn:mavedb:00000044-a-1#2147,NA,NA,p.Pro54Arg,-0.03,0.03,1,P384R +urn:mavedb:00000044-a-1#2148,NA,NA,p.Pro54Arg,0.1,0.03,2,P384R +urn:mavedb:00000044-a-1#2157,NA,NA,p.Pro54Tyr,-0.08,-0.06,1,P384Y +urn:mavedb:00000044-a-1#2158,NA,NA,p.Pro54Tyr,-0.05,-0.06,2,P384Y +urn:mavedb:00000044-a-1#2159,NA,NA,p.Pro54*,NA,NA,1,P384 +urn:mavedb:00000044-a-1#2160,NA,NA,p.Pro54*,NA,NA,2,P384 +urn:mavedb:00000044-a-1#2161,NA,NA,p.Thr55Ala,0,0,1,T385A +urn:mavedb:00000044-a-1#2162,NA,NA,p.Thr55Ala,0,0,2,T385A +urn:mavedb:00000044-a-1#2114,NA,NA,p.Ser53Val,0.01,-0.01,2,S383V +urn:mavedb:00000044-a-1#2115,NA,NA,p.Ser53Trp,-0.2,-0.2,1,S383W +urn:mavedb:00000044-a-1#2184,NA,NA,p.Thr55Asn,0.04,0.01,2,T385N +urn:mavedb:00000044-a-1#2116,NA,NA,p.Ser53Trp,-0.19,-0.2,2,S383W +urn:mavedb:00000044-a-1#2117,NA,NA,p.Ser53Tyr,-0.02,-0.07,1,S383Y +urn:mavedb:00000044-a-1#2185,NA,NA,p.Thr55Pro,-0.04,-0.04,1,T385P +urn:mavedb:00000044-a-1#2085,NA,NA,p.Ser53Asp,0,0.02,1,S383D +urn:mavedb:00000044-a-1#2118,NA,NA,p.Ser53Tyr,-0.12,-0.07,2,S383Y +urn:mavedb:00000044-a-1#2086,NA,NA,p.Ser53Asp,0.04,0.02,2,S383D +urn:mavedb:00000044-a-1#1914,NA,NA,p.Lys48Val,-0.09,-0.09,2,K378V +urn:mavedb:00000044-a-1#1915,NA,NA,p.Lys48Trp,-0.51,-0.6,1,K378W +urn:mavedb:00000044-a-1#1916,NA,NA,p.Lys48Trp,-0.69,-0.6,2,K378W +urn:mavedb:00000044-a-1#1917,NA,NA,p.Lys48Tyr,-0.36,-0.42,1,K378Y +urn:mavedb:00000044-a-1#1918,NA,NA,p.Lys48Tyr,-0.48,-0.42,2,K378Y +urn:mavedb:00000044-a-1#1922,NA,NA,p.Cys49Ala,-1.81,-1.44,2,C379A +urn:mavedb:00000044-a-1#1923,NA,NA,p.Cys49Asp,-4.76,-4.79,1,C379D +urn:mavedb:00000044-a-1#1924,NA,NA,p.Cys49Asp,-4.82,-4.79,2,C379D +urn:mavedb:00000044-a-1#1925,NA,NA,p.Cys49Glu,-4.15,-4.06,1,C379E +urn:mavedb:00000044-a-1#1926,NA,NA,p.Cys49Glu,-3.97,-4.06,2,C379E +urn:mavedb:00000044-a-1#1927,NA,NA,p.Cys49Phe,-0.61,-0.65,1,C379F +urn:mavedb:00000044-a-1#1928,NA,NA,p.Cys49Phe,-0.7,-0.65,2,C379F +urn:mavedb:00000044-a-1#1929,NA,NA,p.Cys49Gly,-4.32,-4.51,1,C379G +urn:mavedb:00000044-a-1#1930,NA,NA,p.Cys49Gly,-4.7,-4.51,2,C379G +urn:mavedb:00000044-a-1#1931,NA,NA,p.Cys49His,-3.14,-2.5,1,C379H +urn:mavedb:00000044-a-1#1932,NA,NA,p.Cys49His,-1.86,-2.5,2,C379H +urn:mavedb:00000044-a-1#1933,NA,NA,p.Cys49Ile,-1.45,-1.24,1,C379I +urn:mavedb:00000044-a-1#1934,NA,NA,p.Cys49Ile,-1.03,-1.24,2,C379I +urn:mavedb:00000044-a-1#1935,NA,NA,p.Cys49Lys,-4.56,-4.7,1,C379K +urn:mavedb:00000044-a-1#1936,NA,NA,p.Cys49Lys,-4.84,-4.7,2,C379K +urn:mavedb:00000044-a-1#1937,NA,NA,p.Cys49Leu,-0.91,-0.97,1,C379L +urn:mavedb:00000044-a-1#1938,NA,NA,p.Cys49Leu,-1.03,-0.97,2,C379L +urn:mavedb:00000044-a-1#1939,NA,NA,p.Cys49Met,-0.84,-0.97,1,C379M +urn:mavedb:00000044-a-1#1940,NA,NA,p.Cys49Met,-1.1,-0.97,2,C379M +urn:mavedb:00000044-a-1#1941,NA,NA,p.Cys49Asn,-4.73,-3.32,1,C379N +urn:mavedb:00000044-a-1#1942,NA,NA,p.Cys49Asn,-1.9,-3.32,2,C379N +urn:mavedb:00000044-a-1#1943,NA,NA,p.Cys49Pro,-3.66,-3.66,1,C379P +urn:mavedb:00000044-a-1#1944,NA,NA,p.Cys49Pro,-3.67,-3.66,2,C379P +urn:mavedb:00000044-a-1#1945,NA,NA,p.Cys49Gln,-2.32,-2.98,1,C379Q +urn:mavedb:00000044-a-1#1946,NA,NA,p.Cys49Gln,-3.64,-2.98,2,C379Q +urn:mavedb:00000044-a-1#1947,NA,NA,p.Cys49Arg,-3.77,-4.12,1,C379R +urn:mavedb:00000044-a-1#1967,NA,NA,p.Tyr50Glu,-2.21,-1.8,1,Y380E +urn:mavedb:00000044-a-1#2090,NA,NA,p.Ser53Phe,-0.14,-0.14,2,S383F +urn:mavedb:00000044-a-1#2091,NA,NA,p.Ser53Gly,-0.12,-0.13,1,S383G +urn:mavedb:00000044-a-1#2092,NA,NA,p.Ser53Gly,-0.14,-0.13,2,S383G +urn:mavedb:00000044-a-1#2093,NA,NA,p.Ser53His,-0.06,-0.08,1,S383H +urn:mavedb:00000044-a-1#2094,NA,NA,p.Ser53His,-0.1,-0.08,2,S383H +urn:mavedb:00000044-a-1#2144,NA,NA,p.Pro54Asn,-0.24,-0.18,2,P384N +urn:mavedb:00000044-a-1#2145,NA,NA,p.Pro54Gln,0.09,0.03,1,P384Q +urn:mavedb:00000044-a-1#2100,NA,NA,p.Ser53Leu,-0.06,-0.07,2,S383L +urn:mavedb:00000044-a-1#2101,NA,NA,p.Ser53Met,-0.02,-0.04,1,S383M +urn:mavedb:00000044-a-1#2121,NA,NA,p.Pro54Ala,0,0.01,1,P384A +urn:mavedb:00000044-a-1#2126,NA,NA,p.Pro54Asp,-0.17,-0.14,2,P384D +urn:mavedb:00000044-a-1#2127,NA,NA,p.Pro54Glu,-0.03,-0.02,1,P384E 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+urn:mavedb:00000044-a-1#2218,NA,NA,p.Lys56Leu,-0.08,-0.07,2,K386L +urn:mavedb:00000044-a-1#2219,NA,NA,p.Lys56Met,-0.03,-0.05,1,K386M +urn:mavedb:00000044-a-1#2220,NA,NA,p.Lys56Met,-0.06,-0.05,2,K386M +urn:mavedb:00000044-a-1#2221,NA,NA,p.Lys56Asn,0,0.04,1,K386N +urn:mavedb:00000044-a-1#2222,NA,NA,p.Lys56Asn,0.08,0.04,2,K386N +urn:mavedb:00000044-a-1#2223,NA,NA,p.Lys56Pro,-0.48,-0.54,1,K386P +urn:mavedb:00000044-a-1#2224,NA,NA,p.Lys56Pro,-0.6,-0.54,2,K386P +urn:mavedb:00000044-a-1#2225,NA,NA,p.Lys56Gln,0.04,0.01,1,K386Q +urn:mavedb:00000044-a-1#2226,NA,NA,p.Lys56Gln,-0.02,0.01,2,K386Q +urn:mavedb:00000044-a-1#2227,NA,NA,p.Lys56Arg,-0.09,-0.06,1,K386R +urn:mavedb:00000044-a-1#2228,NA,NA,p.Lys56Arg,-0.03,-0.06,2,K386R +urn:mavedb:00000044-a-1#2229,NA,NA,p.Lys56Ser,0.03,0.04,1,K386S +urn:mavedb:00000044-a-1#2230,NA,NA,p.Lys56Ser,0.04,0.04,2,K386S +urn:mavedb:00000044-a-1#2231,NA,NA,p.Lys56Thr,0.02,-0.01,1,K386T +urn:mavedb:00000044-a-1#2232,NA,NA,p.Lys56Thr,-0.04,-0.01,2,K386T 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+urn:mavedb:00000044-a-1#2394,NA,NA,p.Leu60Val,-0.13,-0.1,2,L390V +urn:mavedb:00000044-a-1#2395,NA,NA,p.Leu60Trp,-0.12,-0.16,1,L390W +urn:mavedb:00000044-a-1#2396,NA,NA,p.Leu60Trp,-0.19,-0.16,2,L390W +urn:mavedb:00000044-a-1#2397,NA,NA,p.Leu60Tyr,0.02,0.01,1,L390Y +urn:mavedb:00000044-a-1#2398,NA,NA,p.Leu60Tyr,0.01,0.01,2,L390Y +urn:mavedb:00000044-a-1#2399,NA,NA,p.Leu60*,NA,NA,1,L390 +urn:mavedb:00000044-a-1#2400,NA,NA,p.Leu60*,NA,NA,2,L390 +urn:mavedb:00000044-a-1#2401,NA,NA,p.Cys61Ala,-0.06,-0.08,1,C391A +urn:mavedb:00000044-a-1#2402,NA,NA,p.Cys61Ala,-0.1,-0.08,2,C391A +urn:mavedb:00000044-a-1#2403,NA,NA,p.Cys61Asp,-0.16,-0.12,1,C391D +urn:mavedb:00000044-a-1#2404,NA,NA,p.Cys61Asp,-0.08,-0.12,2,C391D +urn:mavedb:00000044-a-1#2405,NA,NA,p.Cys61Glu,-0.07,-0.07,1,C391E +urn:mavedb:00000044-a-1#2406,NA,NA,p.Cys61Glu,-0.08,-0.07,2,C391E +urn:mavedb:00000044-a-1#2407,NA,NA,p.Cys61Phe,-0.15,-0.16,1,C391F +urn:mavedb:00000044-a-1#2408,NA,NA,p.Cys61Phe,-0.18,-0.16,2,C391F +urn:mavedb:00000044-a-1#2455,NA,NA,p.Phe62Lys,-0.34,-0.34,1,F392K +urn:mavedb:00000044-a-1#2432,NA,NA,p.Cys61Thr,-0.07,-0.08,2,C391T +urn:mavedb:00000044-a-1#2433,NA,NA,p.Cys61Val,-0.09,-0.09,1,C391V +urn:mavedb:00000044-a-1#2434,NA,NA,p.Cys61Val,-0.1,-0.09,2,C391V +urn:mavedb:00000044-a-1#2435,NA,NA,p.Cys61Trp,-0.17,-0.17,1,C391W +urn:mavedb:00000044-a-1#2436,NA,NA,p.Cys61Trp,-0.17,-0.17,2,C391W +urn:mavedb:00000044-a-1#2437,NA,NA,p.Cys61Tyr,-0.12,-0.13,1,C391Y +urn:mavedb:00000044-a-1#2438,NA,NA,p.Cys61Tyr,-0.14,-0.13,2,C391Y +urn:mavedb:00000044-a-1#2439,NA,NA,p.Cys61*,NA,NA,1,C391 +urn:mavedb:00000044-a-1#2440,NA,NA,p.Cys61*,NA,NA,2,C391 +urn:mavedb:00000044-a-1#2441,NA,NA,p.Phe62Ala,-0.02,-0.02,1,F392A +urn:mavedb:00000044-a-1#2442,NA,NA,p.Phe62Ala,-0.03,-0.02,2,F392A +urn:mavedb:00000044-a-1#2443,NA,NA,p.Phe62Cys,-0.03,-0.04,1,F392C +urn:mavedb:00000044-a-1#2444,NA,NA,p.Phe62Cys,-0.04,-0.04,2,F392C +urn:mavedb:00000044-a-1#2445,NA,NA,p.Phe62Asp,-0.26,-0.32,1,F392D +urn:mavedb:00000044-a-1#2446,NA,NA,p.Phe62Asp,-0.37,-0.32,2,F392D +urn:mavedb:00000044-a-1#2447,NA,NA,p.Phe62Glu,-0.36,-0.36,1,F392E +urn:mavedb:00000044-a-1#2448,NA,NA,p.Phe62Glu,-0.36,-0.36,2,F392E +urn:mavedb:00000044-a-1#2449,NA,NA,p.Phe62Gly,-0.28,-0.27,1,F392G +urn:mavedb:00000044-a-1#2450,NA,NA,p.Phe62Gly,-0.27,-0.27,2,F392G +urn:mavedb:00000044-a-1#2451,NA,NA,p.Phe62His,-0.06,-0.11,1,F392H +urn:mavedb:00000044-a-1#2452,NA,NA,p.Phe62His,-0.16,-0.11,2,F392H +urn:mavedb:00000044-a-1#2453,NA,NA,p.Phe62Ile,-0.03,-0.05,1,F392I +urn:mavedb:00000044-a-1#2456,NA,NA,p.Phe62Lys,-0.34,-0.34,2,F392K +urn:mavedb:00000044-a-1#2457,NA,NA,p.Phe62Leu,-0.06,-0.08,1,F392L +urn:mavedb:00000044-a-1#2458,NA,NA,p.Phe62Leu,-0.09,-0.08,2,F392L +urn:mavedb:00000044-a-1#2459,NA,NA,p.Phe62Met,-0.07,-0.08,1,F392M +urn:mavedb:00000044-a-1#2460,NA,NA,p.Phe62Met,-0.08,-0.08,2,F392M +urn:mavedb:00000044-a-1#2461,NA,NA,p.Phe62Asn,-0.14,-0.21,1,F392N +urn:mavedb:00000044-a-1#2462,NA,NA,p.Phe62Asn,-0.29,-0.21,2,F392N +urn:mavedb:00000044-a-1#2463,NA,NA,p.Phe62Pro,-0.03,-0.03,1,F392P +urn:mavedb:00000044-a-1#2464,NA,NA,p.Phe62Pro,-0.02,-0.03,2,F392P +urn:mavedb:00000044-a-1#2465,NA,NA,p.Phe62Gln,-0.29,-0.23,1,F392Q +urn:mavedb:00000044-a-1#2466,NA,NA,p.Phe62Gln,-0.18,-0.23,2,F392Q +urn:mavedb:00000044-a-1#2467,NA,NA,p.Phe62Arg,-0.39,-0.4,1,F392R +urn:mavedb:00000044-a-1#2468,NA,NA,p.Phe62Arg,-0.41,-0.4,2,F392R +urn:mavedb:00000044-a-1#2469,NA,NA,p.Phe62Ser,-0.08,-0.11,1,F392S +urn:mavedb:00000044-a-1#2584,NA,NA,p.Val65Asn,-1.06,-1.02,2,V395N +urn:mavedb:00000044-a-1#2409,NA,NA,p.Cys61Gly,-0.18,-0.15,1,C391G +urn:mavedb:00000044-a-1#2410,NA,NA,p.Cys61Gly,-0.13,-0.15,2,C391G +urn:mavedb:00000044-a-1#2411,NA,NA,p.Cys61His,-0.05,-0.05,1,C391H +urn:mavedb:00000044-a-1#2412,NA,NA,p.Cys61His,-0.04,-0.05,2,C391H +urn:mavedb:00000044-a-1#2413,NA,NA,p.Cys61Ile,-0.11,-0.13,1,C391I +urn:mavedb:00000044-a-1#2414,NA,NA,p.Cys61Ile,-0.15,-0.13,2,C391I +urn:mavedb:00000044-a-1#2415,NA,NA,p.Cys61Lys,-0.06,-0.06,1,C391K +urn:mavedb:00000044-a-1#2416,NA,NA,p.Cys61Lys,-0.07,-0.06,2,C391K +urn:mavedb:00000044-a-1#2417,NA,NA,p.Cys61Leu,-0.1,-0.12,1,C391L +urn:mavedb:00000044-a-1#2418,NA,NA,p.Cys61Leu,-0.13,-0.12,2,C391L +urn:mavedb:00000044-a-1#2419,NA,NA,p.Cys61Met,-0.11,-0.12,1,C391M +urn:mavedb:00000044-a-1#2420,NA,NA,p.Cys61Met,-0.12,-0.12,2,C391M +urn:mavedb:00000044-a-1#2421,NA,NA,p.Cys61Asn,-0.06,-0.07,1,C391N +urn:mavedb:00000044-a-1#2422,NA,NA,p.Cys61Asn,-0.08,-0.07,2,C391N +urn:mavedb:00000044-a-1#2423,NA,NA,p.Cys61Pro,-0.03,-0.07,1,C391P +urn:mavedb:00000044-a-1#2424,NA,NA,p.Cys61Pro,-0.1,-0.07,2,C391P +urn:mavedb:00000044-a-1#2425,NA,NA,p.Cys61Gln,-0.04,-0.02,1,C391Q +urn:mavedb:00000044-a-1#2426,NA,NA,p.Cys61Gln,-0.01,-0.02,2,C391Q +urn:mavedb:00000044-a-1#2427,NA,NA,p.Cys61Arg,-0.08,-0.07,1,C391R +urn:mavedb:00000044-a-1#2428,NA,NA,p.Cys61Arg,-0.07,-0.07,2,C391R +urn:mavedb:00000044-a-1#2429,NA,NA,p.Cys61Ser,-0.09,-0.09,1,C391S +urn:mavedb:00000044-a-1#2430,NA,NA,p.Cys61Ser,-0.1,-0.09,2,C391S +urn:mavedb:00000044-a-1#2431,NA,NA,p.Cys61Thr,-0.09,-0.08,1,C391T +urn:mavedb:00000044-a-1#2493,NA,NA,p.Thr63His,-0.04,-0.07,1,T393H +urn:mavedb:00000044-a-1#2494,NA,NA,p.Thr63His,-0.09,-0.07,2,T393H +urn:mavedb:00000044-a-1#2495,NA,NA,p.Thr63Ile,-0.06,-0.09,1,T393I +urn:mavedb:00000044-a-1#2496,NA,NA,p.Thr63Ile,-0.11,-0.09,2,T393I +urn:mavedb:00000044-a-1#2497,NA,NA,p.Thr63Lys,-0.04,-0.03,1,T393K +urn:mavedb:00000044-a-1#2498,NA,NA,p.Thr63Lys,-0.01,-0.03,2,T393K +urn:mavedb:00000044-a-1#2499,NA,NA,p.Thr63Leu,-0.11,-0.13,1,T393L +urn:mavedb:00000044-a-1#2500,NA,NA,p.Thr63Leu,-0.15,-0.13,2,T393L +urn:mavedb:00000044-a-1#2501,NA,NA,p.Thr63Met,-0.12,-0.14,1,T393M +urn:mavedb:00000044-a-1#2471,NA,NA,p.Phe62Thr,0,-0.01,1,F392T +urn:mavedb:00000044-a-1#2472,NA,NA,p.Phe62Thr,-0.02,-0.01,2,F392T +urn:mavedb:00000044-a-1#2473,NA,NA,p.Phe62Val,-0.01,0,1,F392V +urn:mavedb:00000044-a-1#2474,NA,NA,p.Phe62Val,0,0,2,F392V +urn:mavedb:00000044-a-1#2475,NA,NA,p.Phe62Trp,0,0.02,1,F392W +urn:mavedb:00000044-a-1#2476,NA,NA,p.Phe62Trp,0.05,0.02,2,F392W +urn:mavedb:00000044-a-1#2477,NA,NA,p.Phe62Tyr,0.04,0.02,1,F392Y +urn:mavedb:00000044-a-1#2478,NA,NA,p.Phe62Tyr,-0.01,0.02,2,F392Y +urn:mavedb:00000044-a-1#2479,NA,NA,p.Phe62*,NA,NA,1,F392 +urn:mavedb:00000044-a-1#2480,NA,NA,p.Phe62*,NA,NA,2,F392 +urn:mavedb:00000044-a-1#2481,NA,NA,p.Thr63Ala,0.02,0.03,1,T393A +urn:mavedb:00000044-a-1#2482,NA,NA,p.Thr63Ala,0.04,0.03,2,T393A +urn:mavedb:00000044-a-1#2502,NA,NA,p.Thr63Met,-0.16,-0.14,2,T393M +urn:mavedb:00000044-a-1#2483,NA,NA,p.Thr63Cys,-0.11,-0.14,1,T393C +urn:mavedb:00000044-a-1#2470,NA,NA,p.Phe62Ser,-0.12,-0.11,2,F392S +urn:mavedb:00000044-a-1#2484,NA,NA,p.Thr63Cys,-0.17,-0.14,2,T393C +urn:mavedb:00000044-a-1#2485,NA,NA,p.Thr63Asp,-0.04,-0.06,1,T393D +urn:mavedb:00000044-a-1#2486,NA,NA,p.Thr63Asp,-0.07,-0.06,2,T393D +urn:mavedb:00000044-a-1#2487,NA,NA,p.Thr63Glu,-0.01,-0.02,1,T393E +urn:mavedb:00000044-a-1#2488,NA,NA,p.Thr63Glu,-0.03,-0.02,2,T393E +urn:mavedb:00000044-a-1#2489,NA,NA,p.Thr63Phe,-0.16,-0.21,1,T393F +urn:mavedb:00000044-a-1#2490,NA,NA,p.Thr63Phe,-0.26,-0.21,2,T393F +urn:mavedb:00000044-a-1#2491,NA,NA,p.Thr63Gly,-0.08,-0.11,1,T393G +urn:mavedb:00000044-a-1#2492,NA,NA,p.Thr63Gly,-0.14,-0.11,2,T393G +urn:mavedb:00000044-a-1#2503,NA,NA,p.Thr63Asn,-0.02,-0.03,1,T393N +urn:mavedb:00000044-a-1#2504,NA,NA,p.Thr63Asn,-0.03,-0.03,2,T393N +urn:mavedb:00000044-a-1#2505,NA,NA,p.Thr63Pro,-0.14,-0.16,1,T393P +urn:mavedb:00000044-a-1#2506,NA,NA,p.Thr63Pro,-0.19,-0.16,2,T393P +urn:mavedb:00000044-a-1#2507,NA,NA,p.Thr63Gln,-0.03,-0.05,1,T393Q +urn:mavedb:00000044-a-1#2508,NA,NA,p.Thr63Gln,-0.07,-0.05,2,T393Q +urn:mavedb:00000044-a-1#2509,NA,NA,p.Thr63Arg,-0.05,-0.05,1,T393R +urn:mavedb:00000044-a-1#2510,NA,NA,p.Thr63Arg,-0.04,-0.05,2,T393R +urn:mavedb:00000044-a-1#2511,NA,NA,p.Thr63Ser,-0.06,0,1,T393S +urn:mavedb:00000044-a-1#2512,NA,NA,p.Thr63Ser,0.06,0,2,T393S +urn:mavedb:00000044-a-1#2513,NA,NA,p.Thr63Val,-0.05,-0.08,1,T393V +urn:mavedb:00000044-a-1#2514,NA,NA,p.Thr63Val,-0.11,-0.08,2,T393V +urn:mavedb:00000044-a-1#2515,NA,NA,p.Thr63Trp,-0.31,-0.37,1,T393W +urn:mavedb:00000044-a-1#2516,NA,NA,p.Thr63Trp,-0.42,-0.37,2,T393W +urn:mavedb:00000044-a-1#2517,NA,NA,p.Thr63Tyr,-0.08,-0.09,1,T393Y +urn:mavedb:00000044-a-1#2518,NA,NA,p.Thr63Tyr,-0.1,-0.09,2,T393Y +urn:mavedb:00000044-a-1#2519,NA,NA,p.Thr63*,NA,NA,1,T393 +urn:mavedb:00000044-a-1#2520,NA,NA,p.Thr63*,NA,NA,2,T393 +urn:mavedb:00000044-a-1#2521,NA,NA,p.Asn64Ala,0.01,0.01,1,N394A +urn:mavedb:00000044-a-1#2522,NA,NA,p.Asn64Ala,0.01,0.01,2,N394A +urn:mavedb:00000044-a-1#2523,NA,NA,p.Asn64Cys,-0.05,-0.1,1,N394C +urn:mavedb:00000044-a-1#2524,NA,NA,p.Asn64Cys,-0.16,-0.1,2,N394C +urn:mavedb:00000044-a-1#2525,NA,NA,p.Asn64Asp,-0.12,-0.08,1,N394D +urn:mavedb:00000044-a-1#2526,NA,NA,p.Asn64Asp,-0.03,-0.08,2,N394D +urn:mavedb:00000044-a-1#2598,NA,NA,p.Val65Tyr,-0.66,-0.53,2,V395Y +urn:mavedb:00000044-a-1#2585,NA,NA,p.Val65Pro,-2.14,-2.03,1,V395P +urn:mavedb:00000044-a-1#2586,NA,NA,p.Val65Pro,-1.92,-2.03,2,V395P +urn:mavedb:00000044-a-1#2587,NA,NA,p.Val65Gln,-0.46,-0.51,1,V395Q +urn:mavedb:00000044-a-1#2588,NA,NA,p.Val65Gln,-0.57,-0.51,2,V395Q +urn:mavedb:00000044-a-1#2589,NA,NA,p.Val65Arg,-0.56,-0.55,1,V395R +urn:mavedb:00000044-a-1#2590,NA,NA,p.Val65Arg,-0.53,-0.55,2,V395R +urn:mavedb:00000044-a-1#2591,NA,NA,p.Val65Ser,-0.52,-0.51,1,V395S +urn:mavedb:00000044-a-1#2592,NA,NA,p.Val65Ser,-0.5,-0.51,2,V395S +urn:mavedb:00000044-a-1#2593,NA,NA,p.Val65Thr,-0.36,-0.36,1,V395T +urn:mavedb:00000044-a-1#2594,NA,NA,p.Val65Thr,-0.36,-0.36,2,V395T +urn:mavedb:00000044-a-1#2595,NA,NA,p.Val65Trp,-0.64,-0.57,1,V395W +urn:mavedb:00000044-a-1#2596,NA,NA,p.Val65Trp,-0.51,-0.57,2,V395W +urn:mavedb:00000044-a-1#2597,NA,NA,p.Val65Tyr,-0.41,-0.53,1,V395Y +urn:mavedb:00000044-a-1#2601,NA,NA,p.Tyr66Ala,-0.27,-0.38,1,Y396A +urn:mavedb:00000044-a-1#2602,NA,NA,p.Tyr66Ala,-0.48,-0.38,2,Y396A +urn:mavedb:00000044-a-1#2603,NA,NA,p.Tyr66Cys,-0.19,-0.23,1,Y396C +urn:mavedb:00000044-a-1#2604,NA,NA,p.Tyr66Cys,-0.26,-0.23,2,Y396C +urn:mavedb:00000044-a-1#2605,NA,NA,p.Tyr66Asp,-0.24,-0.3,1,Y396D +urn:mavedb:00000044-a-1#2606,NA,NA,p.Tyr66Asp,-0.37,-0.3,2,Y396D +urn:mavedb:00000044-a-1#2607,NA,NA,p.Tyr66Glu,-0.54,-0.52,1,Y396E +urn:mavedb:00000044-a-1#2608,NA,NA,p.Tyr66Glu,-0.5,-0.52,2,Y396E +urn:mavedb:00000044-a-1#2609,NA,NA,p.Tyr66Phe,-0.04,-0.02,1,Y396F +urn:mavedb:00000044-a-1#2610,NA,NA,p.Tyr66Phe,0.01,-0.02,2,Y396F +urn:mavedb:00000044-a-1#2611,NA,NA,p.Tyr66Gly,-0.86,-1.08,1,Y396G +urn:mavedb:00000044-a-1#2612,NA,NA,p.Tyr66Gly,-1.3,-1.08,2,Y396G +urn:mavedb:00000044-a-1#2613,NA,NA,p.Tyr66His,-0.21,-0.29,1,Y396H +urn:mavedb:00000044-a-1#2614,NA,NA,p.Tyr66His,-0.36,-0.29,2,Y396H +urn:mavedb:00000044-a-1#2615,NA,NA,p.Tyr66Ile,-0.02,-0.05,1,Y396I +urn:mavedb:00000044-a-1#2616,NA,NA,p.Tyr66Ile,-0.07,-0.05,2,Y396I +urn:mavedb:00000044-a-1#2617,NA,NA,p.Tyr66Lys,-0.53,-0.51,1,Y396K +urn:mavedb:00000044-a-1#2618,NA,NA,p.Tyr66Lys,-0.5,-0.51,2,Y396K +urn:mavedb:00000044-a-1#2619,NA,NA,p.Tyr66Leu,-0.14,-0.12,1,Y396L +urn:mavedb:00000044-a-1#2620,NA,NA,p.Tyr66Leu,-0.1,-0.12,2,Y396L +urn:mavedb:00000044-a-1#2621,NA,NA,p.Tyr66Met,-0.08,-0.1,1,Y396M +urn:mavedb:00000044-a-1#2622,NA,NA,p.Tyr66Met,-0.12,-0.1,2,Y396M +urn:mavedb:00000044-a-1#4402,NA,NA,p.Leu111Ala,-0.18,-0.11,2,L441A +urn:mavedb:00000044-a-1#4403,NA,NA,p.Leu111Cys,-0.08,-0.18,1,L441C +urn:mavedb:00000044-a-1#4404,NA,NA,p.Leu111Cys,-0.29,-0.18,2,L441C +urn:mavedb:00000044-a-1#4639,NA,NA,p.Gly116*,NA,NA,1,G446 +urn:mavedb:00000044-a-1#4428,NA,NA,p.Leu111Arg,-0.2,-0.13,2,L441R +urn:mavedb:00000044-a-1#4429,NA,NA,p.Leu111Ser,-0.63,-0.63,1,L441S +urn:mavedb:00000044-a-1#4409,NA,NA,p.Leu111Phe,-0.04,-0.07,1,L441F +urn:mavedb:00000044-a-1#4410,NA,NA,p.Leu111Phe,-0.09,-0.07,2,L441F +urn:mavedb:00000044-a-1#4411,NA,NA,p.Leu111Gly,-0.25,-0.32,1,L441G +urn:mavedb:00000044-a-1#4419,NA,NA,p.Leu111Met,-0.03,-0.03,1,L441M +urn:mavedb:00000044-a-1#4420,NA,NA,p.Leu111Met,-0.03,-0.03,2,L441M +urn:mavedb:00000044-a-1#4421,NA,NA,p.Leu111Asn,-0.38,-0.33,1,L441N +urn:mavedb:00000044-a-1#4422,NA,NA,p.Leu111Asn,-0.28,-0.33,2,L441N +urn:mavedb:00000044-a-1#4412,NA,NA,p.Leu111Gly,-0.39,-0.32,2,L441G +urn:mavedb:00000044-a-1#4413,NA,NA,p.Leu111His,-0.13,-0.12,1,L441H +urn:mavedb:00000044-a-1#4423,NA,NA,p.Leu111Pro,-0.54,-0.48,1,L441P +urn:mavedb:00000044-a-1#4424,NA,NA,p.Leu111Pro,-0.41,-0.48,2,L441P +urn:mavedb:00000044-a-1#4405,NA,NA,p.Leu111Asp,0,-0.03,1,L441D +urn:mavedb:00000044-a-1#4406,NA,NA,p.Leu111Asp,-0.06,-0.03,2,L441D +urn:mavedb:00000044-a-1#4407,NA,NA,p.Leu111Glu,-0.05,-0.03,1,L441E +urn:mavedb:00000044-a-1#4408,NA,NA,p.Leu111Glu,-0.01,-0.03,2,L441E +urn:mavedb:00000044-a-1#4414,NA,NA,p.Leu111His,-0.11,-0.12,2,L441H +urn:mavedb:00000044-a-1#4415,NA,NA,p.Leu111Ile,0,0.02,1,L441I +urn:mavedb:00000044-a-1#4416,NA,NA,p.Leu111Ile,0.04,0.02,2,L441I +urn:mavedb:00000044-a-1#4417,NA,NA,p.Leu111Lys,-0.03,-0.01,1,L441K +urn:mavedb:00000044-a-1#4418,NA,NA,p.Leu111Lys,0.01,-0.01,2,L441K +urn:mavedb:00000044-a-1#4430,NA,NA,p.Leu111Ser,-0.64,-0.63,2,L441S +urn:mavedb:00000044-a-1#4431,NA,NA,p.Leu111Thr,-0.79,-0.88,1,L441T +urn:mavedb:00000044-a-1#4432,NA,NA,p.Leu111Thr,-0.96,-0.88,2,L441T +urn:mavedb:00000044-a-1#4433,NA,NA,p.Leu111Val,0.01,0.03,1,L441V +urn:mavedb:00000044-a-1#4434,NA,NA,p.Leu111Val,0.06,0.03,2,L441V +urn:mavedb:00000044-a-1#4435,NA,NA,p.Leu111Trp,0,-0.05,1,L441W +urn:mavedb:00000044-a-1#4436,NA,NA,p.Leu111Trp,-0.1,-0.05,2,L441W +urn:mavedb:00000044-a-1#4437,NA,NA,p.Leu111Tyr,-0.09,-0.14,1,L441Y 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+urn:mavedb:00000044-a-1#4090,NA,NA,p.Val103Phe,-4.48,-4.62,2,V433F +urn:mavedb:00000044-a-1#4091,NA,NA,p.Val103Gly,-4.72,-4.78,1,V433G +urn:mavedb:00000044-a-1#4092,NA,NA,p.Val103Gly,-4.84,-4.78,2,V433G +urn:mavedb:00000044-a-1#4093,NA,NA,p.Val103His,-4.76,-4.77,1,V433H +urn:mavedb:00000044-a-1#4094,NA,NA,p.Val103His,-4.77,-4.77,2,V433H +urn:mavedb:00000044-a-1#4095,NA,NA,p.Val103Ile,-0.08,-0.12,1,V433I +urn:mavedb:00000044-a-1#4096,NA,NA,p.Val103Ile,-0.16,-0.12,2,V433I +urn:mavedb:00000044-a-1#4097,NA,NA,p.Val103Lys,-4.76,-4.79,1,V433K +urn:mavedb:00000044-a-1#4098,NA,NA,p.Val103Lys,-4.82,-4.79,2,V433K +urn:mavedb:00000044-a-1#4099,NA,NA,p.Val103Leu,-1.64,-1.56,1,V433L +urn:mavedb:00000044-a-1#4100,NA,NA,p.Val103Leu,-1.48,-1.56,2,V433L +urn:mavedb:00000044-a-1#4101,NA,NA,p.Val103Met,-1.23,-1.33,1,V433M +urn:mavedb:00000044-a-1#4102,NA,NA,p.Val103Met,-1.43,-1.33,2,V433M +urn:mavedb:00000044-a-1#4103,NA,NA,p.Val103Asn,-4.46,-4.57,1,V433N +urn:mavedb:00000044-a-1#4134,NA,NA,p.Ile104His,-0.66,-0.6,2,I434H +urn:mavedb:00000044-a-1#4135,NA,NA,p.Ile104Lys,-2.48,-2.18,1,I434K +urn:mavedb:00000044-a-1#4136,NA,NA,p.Ile104Lys,-1.87,-2.18,2,I434K +urn:mavedb:00000044-a-1#4137,NA,NA,p.Ile104Leu,-0.03,-0.05,1,I434L +urn:mavedb:00000044-a-1#4138,NA,NA,p.Ile104Leu,-0.06,-0.05,2,I434L +urn:mavedb:00000044-a-1#4140,NA,NA,p.Ile104Met,-0.12,-0.08,2,I434M +urn:mavedb:00000044-a-1#4141,NA,NA,p.Ile104Asn,-3.06,-2.93,1,I434N +urn:mavedb:00000044-a-1#4155,NA,NA,p.Ile104Trp,-0.03,-0.04,1,I434W +urn:mavedb:00000044-a-1#6711,NA,NA,p.Gln168Thr,-0.67,-0.67,1,Q498T +urn:mavedb:00000044-a-1#4156,NA,NA,p.Ile104Trp,-0.06,-0.04,2,I434W +urn:mavedb:00000044-a-1#4154,NA,NA,p.Ile104Val,-0.07,-0.07,2,I434V +urn:mavedb:00000044-a-1#4157,NA,NA,p.Ile104Tyr,-0.02,-0.01,1,I434Y +urn:mavedb:00000044-a-1#4226,NA,NA,p.Trp106Pro,-4.84,-4.59,2,W436P +urn:mavedb:00000044-a-1#4227,NA,NA,p.Trp106Gln,-0.59,-0.66,1,W436Q +urn:mavedb:00000044-a-1#4228,NA,NA,p.Trp106Gln,-0.72,-0.66,2,W436Q +urn:mavedb:00000044-a-1#4229,NA,NA,p.Trp106Arg,-0.57,-0.62,1,W436R +urn:mavedb:00000044-a-1#4230,NA,NA,p.Trp106Arg,-0.68,-0.62,2,W436R +urn:mavedb:00000044-a-1#4231,NA,NA,p.Trp106Ser,-0.59,-0.66,1,W436S +urn:mavedb:00000044-a-1#4232,NA,NA,p.Trp106Ser,-0.73,-0.66,2,W436S +urn:mavedb:00000044-a-1#4163,NA,NA,p.Ala105Asp,-3.77,-3.23,1,A435D +urn:mavedb:00000044-a-1#4233,NA,NA,p.Trp106Thr,-0.65,-0.72,1,W436T +urn:mavedb:00000044-a-1#4165,NA,NA,p.Ala105Glu,-2.61,-3.36,1,A435E +urn:mavedb:00000044-a-1#4306,NA,NA,p.Ser108Pro,-4.46,-4.61,2,S438P +urn:mavedb:00000044-a-1#4193,NA,NA,p.Ala105Val,-0.6,-0.61,1,A435V +urn:mavedb:00000044-a-1#4104,NA,NA,p.Val103Asn,-4.69,-4.57,2,V433N +urn:mavedb:00000044-a-1#4105,NA,NA,p.Val103Pro,-4.76,-4.8,1,V433P +urn:mavedb:00000044-a-1#4106,NA,NA,p.Val103Pro,-4.84,-4.8,2,V433P +urn:mavedb:00000044-a-1#4107,NA,NA,p.Val103Gln,-4.76,-4.8,1,V433Q +urn:mavedb:00000044-a-1#4108,NA,NA,p.Val103Gln,-4.84,-4.8,2,V433Q +urn:mavedb:00000044-a-1#4109,NA,NA,p.Val103Arg,-4.25,-4.48,1,V433R +urn:mavedb:00000044-a-1#4110,NA,NA,p.Val103Arg,-4.7,-4.48,2,V433R +urn:mavedb:00000044-a-1#4111,NA,NA,p.Val103Ser,-4.55,-4.36,1,V433S +urn:mavedb:00000044-a-1#4112,NA,NA,p.Val103Ser,-4.18,-4.36,2,V433S +urn:mavedb:00000044-a-1#4113,NA,NA,p.Val103Thr,-0.66,-0.71,1,V433T +urn:mavedb:00000044-a-1#4114,NA,NA,p.Val103Thr,-0.76,-0.71,2,V433T +urn:mavedb:00000044-a-1#4115,NA,NA,p.Val103Trp,-4.64,-4.74,1,V433W +urn:mavedb:00000044-a-1#4116,NA,NA,p.Val103Trp,-4.84,-4.74,2,V433W +urn:mavedb:00000044-a-1#4117,NA,NA,p.Val103Tyr,-4.49,-4.48,1,V433Y +urn:mavedb:00000044-a-1#4118,NA,NA,p.Val103Tyr,-4.46,-4.48,2,V433Y +urn:mavedb:00000044-a-1#4119,NA,NA,p.Val103*,NA,NA,1,V433 +urn:mavedb:00000044-a-1#4120,NA,NA,p.Val103*,NA,NA,2,V433 +urn:mavedb:00000044-a-1#4121,NA,NA,p.Ile104Ala,-0.32,-0.3,1,I434A +urn:mavedb:00000044-a-1#4122,NA,NA,p.Ile104Ala,-0.29,-0.3,2,I434A +urn:mavedb:00000044-a-1#4123,NA,NA,p.Ile104Cys,-0.2,-0.22,1,I434C +urn:mavedb:00000044-a-1#4124,NA,NA,p.Ile104Cys,-0.24,-0.22,2,I434C +urn:mavedb:00000044-a-1#4125,NA,NA,p.Ile104Asp,-4.76,-3.68,1,I434D +urn:mavedb:00000044-a-1#4126,NA,NA,p.Ile104Asp,-2.6,-3.68,2,I434D +urn:mavedb:00000044-a-1#4127,NA,NA,p.Ile104Glu,-4.47,-4.66,1,I434E +urn:mavedb:00000044-a-1#4128,NA,NA,p.Ile104Glu,-4.84,-4.66,2,I434E +urn:mavedb:00000044-a-1#4130,NA,NA,p.Ile104Phe,0.07,0.03,2,I434F +urn:mavedb:00000044-a-1#6710,NA,NA,p.Gln168Ser,-0.19,-0.17,2,Q498S +urn:mavedb:00000044-a-1#4131,NA,NA,p.Ile104Gly,-0.83,-0.93,1,I434G +urn:mavedb:00000044-a-1#4132,NA,NA,p.Ile104Gly,-1.03,-0.93,2,I434G +urn:mavedb:00000044-a-1#4133,NA,NA,p.Ile104His,-0.53,-0.6,1,I434H +urn:mavedb:00000044-a-1#4139,NA,NA,p.Ile104Met,-0.04,-0.08,1,I434M +urn:mavedb:00000044-a-1#4142,NA,NA,p.Ile104Asn,-2.8,-2.93,2,I434N +urn:mavedb:00000044-a-1#4143,NA,NA,p.Ile104Pro,-4.06,-4.45,1,I434P +urn:mavedb:00000044-a-1#4144,NA,NA,p.Ile104Pro,-4.84,-4.45,2,I434P +urn:mavedb:00000044-a-1#4145,NA,NA,p.Ile104Gln,-0.86,-1.13,1,I434Q +urn:mavedb:00000044-a-1#4146,NA,NA,p.Ile104Gln,-1.41,-1.13,2,I434Q +urn:mavedb:00000044-a-1#4153,NA,NA,p.Ile104Val,-0.06,-0.07,1,I434V +urn:mavedb:00000044-a-1#4147,NA,NA,p.Ile104Arg,-4.14,-4.23,1,I434R +urn:mavedb:00000044-a-1#4148,NA,NA,p.Ile104Arg,-4.32,-4.23,2,I434R +urn:mavedb:00000044-a-1#4149,NA,NA,p.Ile104Ser,-0.66,-0.69,1,I434S +urn:mavedb:00000044-a-1#4150,NA,NA,p.Ile104Ser,-0.72,-0.69,2,I434S +urn:mavedb:00000044-a-1#4151,NA,NA,p.Ile104Thr,-0.38,-0.36,1,I434T +urn:mavedb:00000044-a-1#4152,NA,NA,p.Ile104Thr,-0.33,-0.36,2,I434T +urn:mavedb:00000044-a-1#4158,NA,NA,p.Ile104Tyr,0,-0.01,2,I434Y +urn:mavedb:00000044-a-1#4159,NA,NA,p.Ile104*,NA,NA,1,I434 +urn:mavedb:00000044-a-1#4160,NA,NA,p.Ile104*,NA,NA,2,I434 +urn:mavedb:00000044-a-1#4161,NA,NA,p.Ala105Cys,-0.62,-0.63,1,A435C +urn:mavedb:00000044-a-1#4162,NA,NA,p.Ala105Cys,-0.64,-0.63,2,A435C +urn:mavedb:00000044-a-1#4164,NA,NA,p.Ala105Asp,-2.69,-3.23,2,A435D +urn:mavedb:00000044-a-1#4234,NA,NA,p.Trp106Thr,-0.78,-0.72,2,W436T +urn:mavedb:00000044-a-1#4235,NA,NA,p.Trp106Val,-0.8,-0.85,1,W436V +urn:mavedb:00000044-a-1#4236,NA,NA,p.Trp106Val,-0.91,-0.85,2,W436V +urn:mavedb:00000044-a-1#4166,NA,NA,p.Ala105Glu,-4.11,-3.36,2,A435E +urn:mavedb:00000044-a-1#4237,NA,NA,p.Trp106Tyr,-0.52,-0.49,1,W436Y +urn:mavedb:00000044-a-1#4238,NA,NA,p.Trp106Tyr,-0.46,-0.49,2,W436Y +urn:mavedb:00000044-a-1#4239,NA,NA,p.Trp106*,NA,NA,1,W436 +urn:mavedb:00000044-a-1#4240,NA,NA,p.Trp106*,NA,NA,2,W436 +urn:mavedb:00000044-a-1#4241,NA,NA,p.Asn107Ala,-0.52,-0.55,1,N437A +urn:mavedb:00000044-a-1#4242,NA,NA,p.Asn107Ala,-0.58,-0.55,2,N437A +urn:mavedb:00000044-a-1#4243,NA,NA,p.Asn107Cys,-0.44,-0.42,1,N437C +urn:mavedb:00000044-a-1#4244,NA,NA,p.Asn107Cys,-0.41,-0.42,2,N437C +urn:mavedb:00000044-a-1#4245,NA,NA,p.Asn107Asp,-1.46,-1.48,1,N437D +urn:mavedb:00000044-a-1#4167,NA,NA,p.Ala105Phe,-0.94,-0.89,1,A435F +urn:mavedb:00000044-a-1#4168,NA,NA,p.Ala105Phe,-0.83,-0.89,2,A435F +urn:mavedb:00000044-a-1#4169,NA,NA,p.Ala105Gly,-0.34,-0.36,1,A435G +urn:mavedb:00000044-a-1#4170,NA,NA,p.Ala105Gly,-0.38,-0.36,2,A435G +urn:mavedb:00000044-a-1#4171,NA,NA,p.Ala105His,-0.83,-0.94,1,A435H +urn:mavedb:00000044-a-1#4172,NA,NA,p.Ala105His,-1.05,-0.94,2,A435H +urn:mavedb:00000044-a-1#4173,NA,NA,p.Ala105Ile,-0.72,-0.75,1,A435I +urn:mavedb:00000044-a-1#4174,NA,NA,p.Ala105Ile,-0.78,-0.75,2,A435I +urn:mavedb:00000044-a-1#4175,NA,NA,p.Ala105Lys,-1.61,-1.97,1,A435K +urn:mavedb:00000044-a-1#4176,NA,NA,p.Ala105Lys,-2.32,-1.97,2,A435K +urn:mavedb:00000044-a-1#4177,NA,NA,p.Ala105Leu,-1.44,-1.53,1,A435L +urn:mavedb:00000044-a-1#4178,NA,NA,p.Ala105Leu,-1.63,-1.53,2,A435L +urn:mavedb:00000044-a-1#4179,NA,NA,p.Ala105Met,-0.64,-0.67,1,A435M +urn:mavedb:00000044-a-1#4180,NA,NA,p.Ala105Met,-0.7,-0.67,2,A435M +urn:mavedb:00000044-a-1#4181,NA,NA,p.Ala105Asn,-1.1,-1.13,1,A435N +urn:mavedb:00000044-a-1#4182,NA,NA,p.Ala105Asn,-1.16,-1.13,2,A435N +urn:mavedb:00000044-a-1#4257,NA,NA,p.Asn107Lys,-0.73,-0.78,1,N437K +urn:mavedb:00000044-a-1#4194,NA,NA,p.Ala105Val,-0.62,-0.61,2,A435V +urn:mavedb:00000044-a-1#4195,NA,NA,p.Ala105Trp,-0.48,-0.52,1,A435W +urn:mavedb:00000044-a-1#4216,NA,NA,p.Trp106Ile,-0.86,-0.76,2,W436I +urn:mavedb:00000044-a-1#4196,NA,NA,p.Ala105Trp,-0.55,-0.52,2,A435W +urn:mavedb:00000044-a-1#4270,NA,NA,p.Asn107Ser,-0.57,-0.51,2,N437S +urn:mavedb:00000044-a-1#4271,NA,NA,p.Asn107Thr,-1.12,-1.23,1,N437T +urn:mavedb:00000044-a-1#4272,NA,NA,p.Asn107Thr,-1.33,-1.23,2,N437T +urn:mavedb:00000044-a-1#4273,NA,NA,p.Asn107Val,-1.43,-1.46,1,N437V +urn:mavedb:00000044-a-1#4274,NA,NA,p.Asn107Val,-1.49,-1.46,2,N437V +urn:mavedb:00000044-a-1#4278,NA,NA,p.Asn107Tyr,-3.78,-3.62,2,N437Y +urn:mavedb:00000044-a-1#4183,NA,NA,p.Ala105Pro,-3.85,-4.18,1,A435P +urn:mavedb:00000044-a-1#4184,NA,NA,p.Ala105Pro,-4.5,-4.18,2,A435P +urn:mavedb:00000044-a-1#4185,NA,NA,p.Ala105Gln,-1.16,-1.23,1,A435Q +urn:mavedb:00000044-a-1#4186,NA,NA,p.Ala105Gln,-1.31,-1.23,2,A435Q +urn:mavedb:00000044-a-1#4187,NA,NA,p.Ala105Arg,-2.71,-2.76,1,A435R +urn:mavedb:00000044-a-1#4188,NA,NA,p.Ala105Arg,-2.81,-2.76,2,A435R +urn:mavedb:00000044-a-1#4189,NA,NA,p.Ala105Ser,-0.08,-0.07,1,A435S +urn:mavedb:00000044-a-1#4190,NA,NA,p.Ala105Ser,-0.07,-0.07,2,A435S +urn:mavedb:00000044-a-1#4191,NA,NA,p.Ala105Thr,-0.14,-0.17,1,A435T +urn:mavedb:00000044-a-1#4192,NA,NA,p.Ala105Thr,-0.2,-0.17,2,A435T +urn:mavedb:00000044-a-1#4203,NA,NA,p.Trp106Cys,-0.91,-1,1,W436C +urn:mavedb:00000044-a-1#4204,NA,NA,p.Trp106Cys,-1.09,-1,2,W436C +urn:mavedb:00000044-a-1#4261,NA,NA,p.Asn107Met,-1.51,-1.62,1,N437M +urn:mavedb:00000044-a-1#4205,NA,NA,p.Trp106Asp,-2.61,-2.86,1,W436D +urn:mavedb:00000044-a-1#4206,NA,NA,p.Trp106Asp,-3.1,-2.86,2,W436D +urn:mavedb:00000044-a-1#4207,NA,NA,p.Trp106Glu,-1.29,-1.37,1,W436E +urn:mavedb:00000044-a-1#4208,NA,NA,p.Trp106Glu,-1.44,-1.37,2,W436E +urn:mavedb:00000044-a-1#4209,NA,NA,p.Trp106Phe,-0.42,-0.39,1,W436F +urn:mavedb:00000044-a-1#4210,NA,NA,p.Trp106Phe,-0.36,-0.39,2,W436F +urn:mavedb:00000044-a-1#4211,NA,NA,p.Trp106Gly,-1.3,-1.29,1,W436G +urn:mavedb:00000044-a-1#4212,NA,NA,p.Trp106Gly,-1.29,-1.29,2,W436G +urn:mavedb:00000044-a-1#4213,NA,NA,p.Trp106His,-0.89,-0.89,1,W436H +urn:mavedb:00000044-a-1#4214,NA,NA,p.Trp106His,-0.9,-0.89,2,W436H +urn:mavedb:00000044-a-1#4215,NA,NA,p.Trp106Ile,-0.66,-0.76,1,W436I +urn:mavedb:00000044-a-1#4217,NA,NA,p.Trp106Lys,-0.64,-0.67,1,W436K +urn:mavedb:00000044-a-1#4218,NA,NA,p.Trp106Lys,-0.7,-0.67,2,W436K +urn:mavedb:00000044-a-1#4219,NA,NA,p.Trp106Leu,-0.72,-0.78,1,W436L +urn:mavedb:00000044-a-1#4220,NA,NA,p.Trp106Leu,-0.84,-0.78,2,W436L +urn:mavedb:00000044-a-1#4221,NA,NA,p.Trp106Met,-0.55,-0.56,1,W436M +urn:mavedb:00000044-a-1#4222,NA,NA,p.Trp106Met,-0.56,-0.56,2,W436M +urn:mavedb:00000044-a-1#4197,NA,NA,p.Ala105Tyr,-0.48,-0.5,1,A435Y +urn:mavedb:00000044-a-1#4198,NA,NA,p.Ala105Tyr,-0.52,-0.5,2,A435Y +urn:mavedb:00000044-a-1#4199,NA,NA,p.Ala105*,NA,NA,1,A435 +urn:mavedb:00000044-a-1#4200,NA,NA,p.Ala105*,NA,NA,2,A435 +urn:mavedb:00000044-a-1#4201,NA,NA,p.Trp106Ala,-0.7,-0.75,1,W436A +urn:mavedb:00000044-a-1#4202,NA,NA,p.Trp106Ala,-0.81,-0.75,2,W436A +urn:mavedb:00000044-a-1#4223,NA,NA,p.Trp106Asn,-1.34,-1.49,1,W436N +urn:mavedb:00000044-a-1#4224,NA,NA,p.Trp106Asn,-1.65,-1.49,2,W436N +urn:mavedb:00000044-a-1#4225,NA,NA,p.Trp106Pro,-4.35,-4.59,1,W436P +urn:mavedb:00000044-a-1#4246,NA,NA,p.Asn107Asp,-1.51,-1.48,2,N437D +urn:mavedb:00000044-a-1#4247,NA,NA,p.Asn107Glu,-0.92,-0.96,1,N437E +urn:mavedb:00000044-a-1#4248,NA,NA,p.Asn107Glu,-1.01,-0.96,2,N437E +urn:mavedb:00000044-a-1#4249,NA,NA,p.Asn107Phe,-4.09,-4.24,1,N437F +urn:mavedb:00000044-a-1#4250,NA,NA,p.Asn107Phe,-4.39,-4.24,2,N437F +urn:mavedb:00000044-a-1#4251,NA,NA,p.Asn107Gly,-0.52,-0.56,1,N437G +urn:mavedb:00000044-a-1#4252,NA,NA,p.Asn107Gly,-0.61,-0.56,2,N437G +urn:mavedb:00000044-a-1#4253,NA,NA,p.Asn107His,-1.86,-1.89,1,N437H +urn:mavedb:00000044-a-1#4279,NA,NA,p.Asn107*,NA,NA,1,N437 +urn:mavedb:00000044-a-1#4254,NA,NA,p.Asn107His,-1.92,-1.89,2,N437H +urn:mavedb:00000044-a-1#4255,NA,NA,p.Asn107Ile,-2.19,-2.21,1,N437I +urn:mavedb:00000044-a-1#4256,NA,NA,p.Asn107Ile,-2.22,-2.21,2,N437I +urn:mavedb:00000044-a-1#4258,NA,NA,p.Asn107Lys,-0.83,-0.78,2,N437K +urn:mavedb:00000044-a-1#4259,NA,NA,p.Asn107Leu,-2.07,-2.15,1,N437L +urn:mavedb:00000044-a-1#4260,NA,NA,p.Asn107Leu,-2.22,-2.15,2,N437L +urn:mavedb:00000044-a-1#4262,NA,NA,p.Asn107Met,-1.73,-1.62,2,N437M +urn:mavedb:00000044-a-1#4275,NA,NA,p.Asn107Trp,-2.85,-2.96,1,N437W +urn:mavedb:00000044-a-1#4276,NA,NA,p.Asn107Trp,-3.07,-2.96,2,N437W +urn:mavedb:00000044-a-1#4263,NA,NA,p.Asn107Pro,-0.37,-0.36,1,N437P +urn:mavedb:00000044-a-1#4264,NA,NA,p.Asn107Pro,-0.36,-0.36,2,N437P +urn:mavedb:00000044-a-1#4265,NA,NA,p.Asn107Gln,-0.66,-0.75,1,N437Q +urn:mavedb:00000044-a-1#4277,NA,NA,p.Asn107Tyr,-3.45,-3.62,1,N437Y +urn:mavedb:00000044-a-1#4269,NA,NA,p.Asn107Ser,-0.46,-0.51,1,N437S +urn:mavedb:00000044-a-1#4266,NA,NA,p.Asn107Gln,-0.84,-0.75,2,N437Q +urn:mavedb:00000044-a-1#4267,NA,NA,p.Asn107Arg,-0.71,-0.75,1,N437R +urn:mavedb:00000044-a-1#4268,NA,NA,p.Asn107Arg,-0.8,-0.75,2,N437R +urn:mavedb:00000044-a-1#4283,NA,NA,p.Ser108Cys,-0.28,-0.38,1,S438C +urn:mavedb:00000044-a-1#4284,NA,NA,p.Ser108Cys,-0.47,-0.38,2,S438C +urn:mavedb:00000044-a-1#4285,NA,NA,p.Ser108Asp,-2.22,-2.26,1,S438D +urn:mavedb:00000044-a-1#4286,NA,NA,p.Ser108Asp,-2.31,-2.26,2,S438D +urn:mavedb:00000044-a-1#4287,NA,NA,p.Ser108Glu,-2.48,-2.21,1,S438E +urn:mavedb:00000044-a-1#4288,NA,NA,p.Ser108Glu,-1.95,-2.21,2,S438E +urn:mavedb:00000044-a-1#4289,NA,NA,p.Ser108Phe,-2.7,-2.79,1,S438F +urn:mavedb:00000044-a-1#4290,NA,NA,p.Ser108Phe,-2.87,-2.79,2,S438F +urn:mavedb:00000044-a-1#4291,NA,NA,p.Ser108Gly,-0.66,-0.65,1,S438G +urn:mavedb:00000044-a-1#4292,NA,NA,p.Ser108Gly,-0.64,-0.65,2,S438G +urn:mavedb:00000044-a-1#4293,NA,NA,p.Ser108His,-2.43,-2.44,1,S438H +urn:mavedb:00000044-a-1#4294,NA,NA,p.Ser108His,-2.45,-2.44,2,S438H +urn:mavedb:00000044-a-1#4295,NA,NA,p.Ser108Ile,-2.34,-2.39,1,S438I +urn:mavedb:00000044-a-1#4280,NA,NA,p.Asn107*,NA,NA,2,N437 +urn:mavedb:00000044-a-1#4281,NA,NA,p.Ser108Ala,0.03,-0.01,1,S438A +urn:mavedb:00000044-a-1#4282,NA,NA,p.Ser108Ala,-0.04,-0.01,2,S438A +urn:mavedb:00000044-a-1#4311,NA,NA,p.Ser108Thr,-0.13,-0.1,1,S438T +urn:mavedb:00000044-a-1#4312,NA,NA,p.Ser108Thr,-0.07,-0.1,2,S438T +urn:mavedb:00000044-a-1#4313,NA,NA,p.Ser108Val,-0.61,-0.76,1,S438V +urn:mavedb:00000044-a-1#4314,NA,NA,p.Ser108Val,-0.91,-0.76,2,S438V +urn:mavedb:00000044-a-1#4321,NA,NA,p.Asn109Ala,0,-0.17,1,N439A +urn:mavedb:00000044-a-1#4322,NA,NA,p.Asn109Ala,-0.34,-0.17,2,N439A +urn:mavedb:00000044-a-1#4323,NA,NA,p.Asn109Cys,-0.14,-0.12,1,N439C +urn:mavedb:00000044-a-1#4326,NA,NA,p.Asn109Asp,-1.3,-1.15,2,N439D +urn:mavedb:00000044-a-1#4327,NA,NA,p.Asn109Glu,-1.5,-2.66,1,N439E +urn:mavedb:00000044-a-1#4328,NA,NA,p.Asn109Glu,-3.82,-2.66,2,N439E +urn:mavedb:00000044-a-1#4329,NA,NA,p.Asn109Phe,-1.08,-1.14,1,N439F +urn:mavedb:00000044-a-1#4330,NA,NA,p.Asn109Phe,-1.19,-1.14,2,N439F +urn:mavedb:00000044-a-1#4337,NA,NA,p.Asn109Lys,0.11,0.04,1,N439K +urn:mavedb:00000044-a-1#4338,NA,NA,p.Asn109Lys,-0.02,0.04,2,N439K +urn:mavedb:00000044-a-1#4339,NA,NA,p.Asn109Leu,-0.04,-0.06,1,N439L +urn:mavedb:00000044-a-1#4343,NA,NA,p.Asn109Pro,-2.13,-2.39,1,N439P +urn:mavedb:00000044-a-1#4344,NA,NA,p.Asn109Pro,-2.65,-2.39,2,N439P +urn:mavedb:00000044-a-1#4345,NA,NA,p.Asn109Gln,-0.32,-0.45,1,N439Q +urn:mavedb:00000044-a-1#4346,NA,NA,p.Asn109Gln,-0.57,-0.45,2,N439Q +urn:mavedb:00000044-a-1#4359,NA,NA,p.Asn109*,NA,NA,1,N439 +urn:mavedb:00000044-a-1#4350,NA,NA,p.Asn109Ser,-1.4,-1.22,2,N439S +urn:mavedb:00000044-a-1#6716,NA,NA,p.Gln168Trp,0.14,0.07,2,Q498W +urn:mavedb:00000044-a-1#4351,NA,NA,p.Asn109Thr,-1.02,-1.08,1,N439T +urn:mavedb:00000044-a-1#4352,NA,NA,p.Asn109Thr,-1.14,-1.08,2,N439T +urn:mavedb:00000044-a-1#4353,NA,NA,p.Asn109Val,-0.06,-0.04,1,N439V +urn:mavedb:00000044-a-1#4354,NA,NA,p.Asn109Val,-0.03,-0.04,2,N439V +urn:mavedb:00000044-a-1#4360,NA,NA,p.Asn109*,NA,NA,2,N439 +urn:mavedb:00000044-a-1#4357,NA,NA,p.Asn109Tyr,-1.19,-1.2,1,N439Y +urn:mavedb:00000044-a-1#4358,NA,NA,p.Asn109Tyr,-1.22,-1.2,2,N439Y +urn:mavedb:00000044-a-1#4362,NA,NA,p.Asn110Ala,-0.01,0.01,2,N440A +urn:mavedb:00000044-a-1#4369,NA,NA,p.Asn110Phe,0.01,-0.03,1,N440F +urn:mavedb:00000044-a-1#4370,NA,NA,p.Asn110Phe,-0.07,-0.03,2,N440F +urn:mavedb:00000044-a-1#6708,NA,NA,p.Gln168Arg,-0.07,-0.06,2,Q498R +urn:mavedb:00000044-a-1#6709,NA,NA,p.Gln168Ser,-0.15,-0.17,1,Q498S +urn:mavedb:00000044-a-1#4395,NA,NA,p.Asn110Trp,-0.14,-0.11,1,N440W +urn:mavedb:00000044-a-1#4372,NA,NA,p.Asn110Gly,-0.04,-0.01,2,N440G +urn:mavedb:00000044-a-1#4373,NA,NA,p.Asn110His,0.04,0.02,1,N440H +urn:mavedb:00000044-a-1#4378,NA,NA,p.Asn110Lys,0.09,0.07,2,N440K +urn:mavedb:00000044-a-1#2527,NA,NA,p.Asn64Glu,-0.01,-0.02,1,N394E +urn:mavedb:00000044-a-1#2528,NA,NA,p.Asn64Glu,-0.04,-0.02,2,N394E +urn:mavedb:00000044-a-1#2529,NA,NA,p.Asn64Phe,-0.05,-0.07,1,N394F +urn:mavedb:00000044-a-1#2530,NA,NA,p.Asn64Phe,-0.08,-0.07,2,N394F +urn:mavedb:00000044-a-1#2531,NA,NA,p.Asn64Gly,-0.06,-0.08,1,N394G +urn:mavedb:00000044-a-1#2532,NA,NA,p.Asn64Gly,-0.11,-0.08,2,N394G +urn:mavedb:00000044-a-1#2533,NA,NA,p.Asn64His,0.04,0,1,N394H +urn:mavedb:00000044-a-1#2534,NA,NA,p.Asn64His,-0.05,0,2,N394H +urn:mavedb:00000044-a-1#2535,NA,NA,p.Asn64Ile,-0.14,-0.13,1,N394I +urn:mavedb:00000044-a-1#2536,NA,NA,p.Asn64Ile,-0.11,-0.13,2,N394I +urn:mavedb:00000044-a-1#2537,NA,NA,p.Asn64Lys,-0.08,-0.1,1,N394K +urn:mavedb:00000044-a-1#2538,NA,NA,p.Asn64Lys,-0.12,-0.1,2,N394K +urn:mavedb:00000044-a-1#2539,NA,NA,p.Asn64Leu,-0.09,-0.12,1,N394L +urn:mavedb:00000044-a-1#2540,NA,NA,p.Asn64Leu,-0.14,-0.12,2,N394L +urn:mavedb:00000044-a-1#2541,NA,NA,p.Asn64Met,-0.05,-0.05,1,N394M +urn:mavedb:00000044-a-1#2542,NA,NA,p.Asn64Met,-0.05,-0.05,2,N394M +urn:mavedb:00000044-a-1#2543,NA,NA,p.Asn64Pro,-0.06,-0.08,1,N394P +urn:mavedb:00000044-a-1#2544,NA,NA,p.Asn64Pro,-0.09,-0.08,2,N394P +urn:mavedb:00000044-a-1#2545,NA,NA,p.Asn64Gln,-0.01,-0.06,1,N394Q +urn:mavedb:00000044-a-1#2546,NA,NA,p.Asn64Gln,-0.1,-0.06,2,N394Q +urn:mavedb:00000044-a-1#2568,NA,NA,p.Val65Glu,-1.1,-1.02,2,V395E +urn:mavedb:00000044-a-1#2569,NA,NA,p.Val65Phe,-0.24,-0.19,1,V395F +urn:mavedb:00000044-a-1#2547,NA,NA,p.Asn64Arg,-0.06,-0.08,1,N394R +urn:mavedb:00000044-a-1#2548,NA,NA,p.Asn64Arg,-0.09,-0.08,2,N394R +urn:mavedb:00000044-a-1#2549,NA,NA,p.Asn64Ser,0,0.01,1,N394S +urn:mavedb:00000044-a-1#2550,NA,NA,p.Asn64Ser,0.02,0.01,2,N394S 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+urn:mavedb:00000044-a-1#2566,NA,NA,p.Val65Asp,-3.87,-3.52,2,V395D +urn:mavedb:00000044-a-1#2567,NA,NA,p.Val65Glu,-0.94,-1.02,1,V395E +urn:mavedb:00000044-a-1#2570,NA,NA,p.Val65Phe,-0.15,-0.19,2,V395F +urn:mavedb:00000044-a-1#2571,NA,NA,p.Val65Gly,-0.16,-0.18,1,V395G +urn:mavedb:00000044-a-1#2572,NA,NA,p.Val65Gly,-0.2,-0.18,2,V395G +urn:mavedb:00000044-a-1#2573,NA,NA,p.Val65His,-0.62,-0.59,1,V395H +urn:mavedb:00000044-a-1#2574,NA,NA,p.Val65His,-0.57,-0.59,2,V395H +urn:mavedb:00000044-a-1#2575,NA,NA,p.Val65Ile,0,0,1,V395I +urn:mavedb:00000044-a-1#2576,NA,NA,p.Val65Ile,0,0,2,V395I +urn:mavedb:00000044-a-1#2577,NA,NA,p.Val65Lys,-0.82,-0.9,1,V395K +urn:mavedb:00000044-a-1#2578,NA,NA,p.Val65Lys,-0.98,-0.9,2,V395K +urn:mavedb:00000044-a-1#2579,NA,NA,p.Val65Leu,-0.08,-0.03,1,V395L +urn:mavedb:00000044-a-1#2580,NA,NA,p.Val65Leu,0.02,-0.03,2,V395L +urn:mavedb:00000044-a-1#2581,NA,NA,p.Val65Met,0,0.04,1,V395M +urn:mavedb:00000044-a-1#2582,NA,NA,p.Val65Met,0.08,0.04,2,V395M +urn:mavedb:00000044-a-1#2583,NA,NA,p.Val65Asn,-0.97,-1.02,1,V395N +urn:mavedb:00000044-a-1#4398,NA,NA,p.Asn110Tyr,-0.1,-0.07,2,N440Y +urn:mavedb:00000044-a-1#4396,NA,NA,p.Asn110Trp,-0.08,-0.11,2,N440W +urn:mavedb:00000044-a-1#4397,NA,NA,p.Asn110Tyr,-0.04,-0.07,1,N440Y +urn:mavedb:00000044-a-1#4399,NA,NA,p.Asn110*,NA,NA,1,N440 +urn:mavedb:00000044-a-1#4400,NA,NA,p.Asn110*,NA,NA,2,N440 +urn:mavedb:00000044-a-1#4401,NA,NA,p.Leu111Ala,-0.05,-0.11,1,L441A +urn:mavedb:00000044-a-1#4425,NA,NA,p.Leu111Gln,-0.04,-0.03,1,L441Q +urn:mavedb:00000044-a-1#4640,NA,NA,p.Gly116*,NA,NA,2,G446 +urn:mavedb:00000044-a-1#4426,NA,NA,p.Leu111Gln,-0.03,-0.03,2,L441Q +urn:mavedb:00000044-a-1#4427,NA,NA,p.Leu111Arg,-0.06,-0.13,1,L441R +urn:mavedb:00000044-a-1#4516,NA,NA,p.Ser113Trp,-2.46,-2.39,2,S443W +urn:mavedb:00000044-a-1#4517,NA,NA,p.Ser113Tyr,-2.07,-2.17,1,S443Y +urn:mavedb:00000044-a-1#4518,NA,NA,p.Ser113Tyr,-2.28,-2.17,2,S443Y +urn:mavedb:00000044-a-1#4519,NA,NA,p.Ser113*,NA,NA,1,S443 +urn:mavedb:00000044-a-1#4520,NA,NA,p.Ser113*,NA,NA,2,S443 +urn:mavedb:00000044-a-1#4521,NA,NA,p.Lys114Ala,0,-0.01,1,K444A +urn:mavedb:00000044-a-1#4523,NA,NA,p.Lys114Cys,-0.08,-0.14,1,K444C +urn:mavedb:00000044-a-1#4374,NA,NA,p.Asn110His,0.01,0.02,2,N440H +urn:mavedb:00000044-a-1#4375,NA,NA,p.Asn110Ile,-0.09,-0.09,1,N440I +urn:mavedb:00000044-a-1#4376,NA,NA,p.Asn110Ile,-0.09,-0.09,2,N440I +urn:mavedb:00000044-a-1#4377,NA,NA,p.Asn110Lys,0.05,0.07,1,N440K +urn:mavedb:00000044-a-1#4380,NA,NA,p.Asn110Leu,-0.11,-0.07,2,N440L +urn:mavedb:00000044-a-1#4379,NA,NA,p.Asn110Leu,-0.04,-0.07,1,N440L +urn:mavedb:00000044-a-1#6651,NA,NA,p.Phe167His,-2.87,-3.07,1,F497H +urn:mavedb:00000044-a-1#6676,NA,NA,p.Phe167Trp,-1.89,-1.81,2,F497W +urn:mavedb:00000044-a-1#6691,NA,NA,p.Gln168Gly,-0.58,-0.61,1,Q498G +urn:mavedb:00000044-a-1#6652,NA,NA,p.Phe167His,-3.27,-3.07,2,F497H +urn:mavedb:00000044-a-1#6677,NA,NA,p.Phe167Tyr,-0.55,-0.59,1,F497Y +urn:mavedb:00000044-a-1#6653,NA,NA,p.Phe167Ile,-4.76,-4.8,1,F497I +urn:mavedb:00000044-a-1#6654,NA,NA,p.Phe167Ile,-4.84,-4.8,2,F497I +urn:mavedb:00000044-a-1#6655,NA,NA,p.Phe167Lys,-4.76,-4.8,1,F497K +urn:mavedb:00000044-a-1#6678,NA,NA,p.Phe167Tyr,-0.62,-0.59,2,F497Y +urn:mavedb:00000044-a-1#6679,NA,NA,p.Phe167*,NA,NA,1,F497 +urn:mavedb:00000044-a-1#6681,NA,NA,p.Gln168Ala,-0.01,-0.05,1,Q498A +urn:mavedb:00000044-a-1#6682,NA,NA,p.Gln168Ala,-0.08,-0.05,2,Q498A +urn:mavedb:00000044-a-1#6683,NA,NA,p.Gln168Cys,-1.23,-1.41,1,Q498C +urn:mavedb:00000044-a-1#6662,NA,NA,p.Phe167Asn,-4.5,-4.42,2,F497N +urn:mavedb:00000044-a-1#6688,NA,NA,p.Gln168Glu,-1.04,-0.98,2,Q498E +urn:mavedb:00000044-a-1#6663,NA,NA,p.Phe167Pro,-4.76,-4.8,1,F497P +urn:mavedb:00000044-a-1#6664,NA,NA,p.Phe167Pro,-4.84,-4.8,2,F497P +urn:mavedb:00000044-a-1#6665,NA,NA,p.Phe167Gln,-4.66,-4.75,1,F497Q +urn:mavedb:00000044-a-1#6668,NA,NA,p.Phe167Arg,-4.84,-4.8,2,F497R +urn:mavedb:00000044-a-1#6692,NA,NA,p.Gln168Gly,-0.64,-0.61,2,Q498G +urn:mavedb:00000044-a-1#6697,NA,NA,p.Gln168Lys,-2.2,-2.26,1,Q498K +urn:mavedb:00000044-a-1#6671,NA,NA,p.Phe167Thr,-4.76,-4.8,1,F497T +urn:mavedb:00000044-a-1#6698,NA,NA,p.Gln168Lys,-2.32,-2.26,2,Q498K +urn:mavedb:00000044-a-1#6699,NA,NA,p.Gln168Leu,-1.5,-1.58,1,Q498L +urn:mavedb:00000044-a-1#6706,NA,NA,p.Gln168Pro,-3.54,-3.14,2,Q498P +urn:mavedb:00000044-a-1#6707,NA,NA,p.Gln168Arg,-0.06,-0.06,1,Q498R +urn:mavedb:00000044-a-1#6717,NA,NA,p.Gln168Tyr,0.01,0.16,1,Q498Y +urn:mavedb:00000044-a-1#6723,NA,NA,p.Pro169Cys,-1.01,-1.07,1,P499C +urn:mavedb:00000044-a-1#6724,NA,NA,p.Pro169Cys,-1.14,-1.07,2,P499C +urn:mavedb:00000044-a-1#6725,NA,NA,p.Pro169Asp,-0.86,-0.92,1,P499D +urn:mavedb:00000044-a-1#6726,NA,NA,p.Pro169Asp,-0.98,-0.92,2,P499D +urn:mavedb:00000044-a-1#6727,NA,NA,p.Pro169Glu,-0.99,-1.1,1,P499E +urn:mavedb:00000044-a-1#6728,NA,NA,p.Pro169Glu,-1.21,-1.1,2,P499E +urn:mavedb:00000044-a-1#6729,NA,NA,p.Pro169Phe,-0.35,-0.41,1,P499F +urn:mavedb:00000044-a-1#6730,NA,NA,p.Pro169Phe,-0.46,-0.41,2,P499F +urn:mavedb:00000044-a-1#6731,NA,NA,p.Pro169Gly,-0.91,-1.02,1,P499G +urn:mavedb:00000044-a-1#6732,NA,NA,p.Pro169Gly,-1.13,-1.02,2,P499G +urn:mavedb:00000044-a-1#6733,NA,NA,p.Pro169His,-0.32,-0.47,1,P499H +urn:mavedb:00000044-a-1#6734,NA,NA,p.Pro169His,-0.62,-0.47,2,P499H +urn:mavedb:00000044-a-1#6735,NA,NA,p.Pro169Ile,-0.39,-0.46,1,P499I +urn:mavedb:00000044-a-1#6736,NA,NA,p.Pro169Ile,-0.53,-0.46,2,P499I +urn:mavedb:00000044-a-1#6737,NA,NA,p.Pro169Lys,-0.06,-0.12,1,P499K +urn:mavedb:00000044-a-1#6738,NA,NA,p.Pro169Lys,-0.18,-0.12,2,P499K +urn:mavedb:00000044-a-1#6739,NA,NA,p.Pro169Leu,-0.34,-0.36,1,P499L +urn:mavedb:00000044-a-1#6740,NA,NA,p.Pro169Leu,-0.38,-0.36,2,P499L +urn:mavedb:00000044-a-1#6741,NA,NA,p.Pro169Met,-0.43,-0.46,1,P499M +urn:mavedb:00000044-a-1#6742,NA,NA,p.Pro169Met,-0.49,-0.46,2,P499M +urn:mavedb:00000044-a-1#6743,NA,NA,p.Pro169Asn,-0.36,-0.37,1,P499N +urn:mavedb:00000044-a-1#6744,NA,NA,p.Pro169Asn,-0.37,-0.37,2,P499N +urn:mavedb:00000044-a-1#6745,NA,NA,p.Pro169Gln,-0.52,-0.59,1,P499Q +urn:mavedb:00000044-a-1#6746,NA,NA,p.Pro169Gln,-0.66,-0.59,2,P499Q +urn:mavedb:00000044-a-1#6748,NA,NA,p.Pro169Arg,-0.16,-0.14,2,P499R +urn:mavedb:00000044-a-1#6756,NA,NA,p.Pro169Trp,-1.01,-0.99,2,P499W +urn:mavedb:00000044-a-1#6759,NA,NA,p.Pro169*,NA,NA,1,P499 +urn:mavedb:00000044-a-1#6751,NA,NA,p.Pro169Thr,-0.11,-0.15,1,P499T +urn:mavedb:00000044-a-1#4381,NA,NA,p.Asn110Met,0,0,1,N440M +urn:mavedb:00000044-a-1#4382,NA,NA,p.Asn110Met,-0.01,0,2,N440M +urn:mavedb:00000044-a-1#4383,NA,NA,p.Asn110Pro,0.06,-0.05,1,N440P +urn:mavedb:00000044-a-1#4384,NA,NA,p.Asn110Pro,-0.15,-0.05,2,N440P +urn:mavedb:00000044-a-1#4385,NA,NA,p.Asn110Gln,-0.03,-0.08,1,N440Q +urn:mavedb:00000044-a-1#4386,NA,NA,p.Asn110Gln,-0.12,-0.08,2,N440Q +urn:mavedb:00000044-a-1#4387,NA,NA,p.Asn110Arg,-0.04,-0.03,1,N440R +urn:mavedb:00000044-a-1#4388,NA,NA,p.Asn110Arg,-0.02,-0.03,2,N440R +urn:mavedb:00000044-a-1#4389,NA,NA,p.Asn110Ser,0.02,0.04,1,N440S +urn:mavedb:00000044-a-1#4390,NA,NA,p.Asn110Ser,0.06,0.04,2,N440S +urn:mavedb:00000044-a-1#4391,NA,NA,p.Asn110Thr,-0.03,-0.02,1,N440T +urn:mavedb:00000044-a-1#4392,NA,NA,p.Asn110Thr,-0.01,-0.02,2,N440T +urn:mavedb:00000044-a-1#4393,NA,NA,p.Asn110Val,0.02,-0.02,1,N440V +urn:mavedb:00000044-a-1#4394,NA,NA,p.Asn110Val,-0.06,-0.02,2,N440V +urn:mavedb:00000044-a-1#6648,NA,NA,p.Phe167Glu,-4.84,-4.8,2,F497E +urn:mavedb:00000044-a-1#6649,NA,NA,p.Phe167Gly,-2.84,-3.84,1,F497G +urn:mavedb:00000044-a-1#6674,NA,NA,p.Phe167Val,-4.82,-4.73,2,F497V +urn:mavedb:00000044-a-1#6685,NA,NA,p.Gln168Asp,-1.24,-1.27,1,Q498D +urn:mavedb:00000044-a-1#6675,NA,NA,p.Phe167Trp,-1.73,-1.81,1,F497W +urn:mavedb:00000044-a-1#6686,NA,NA,p.Gln168Asp,-1.29,-1.27,2,Q498D +urn:mavedb:00000044-a-1#6650,NA,NA,p.Phe167Gly,-4.84,-3.84,2,F497G +urn:mavedb:00000044-a-1#6713,NA,NA,p.Gln168Val,-1.2,-1.24,1,Q498V +urn:mavedb:00000044-a-1#6656,NA,NA,p.Phe167Lys,-4.84,-4.8,2,F497K +urn:mavedb:00000044-a-1#6657,NA,NA,p.Phe167Leu,-2,-2.05,1,F497L +urn:mavedb:00000044-a-1#6658,NA,NA,p.Phe167Leu,-2.09,-2.05,2,F497L +urn:mavedb:00000044-a-1#6659,NA,NA,p.Phe167Met,-2.32,-2.35,1,F497M +urn:mavedb:00000044-a-1#6660,NA,NA,p.Phe167Met,-2.38,-2.35,2,F497M +urn:mavedb:00000044-a-1#6714,NA,NA,p.Gln168Val,-1.29,-1.24,2,Q498V +urn:mavedb:00000044-a-1#6680,NA,NA,p.Phe167*,NA,NA,2,F497 +urn:mavedb:00000044-a-1#6684,NA,NA,p.Gln168Cys,-1.59,-1.41,2,Q498C +urn:mavedb:00000044-a-1#6661,NA,NA,p.Phe167Asn,-4.34,-4.42,1,F497N +urn:mavedb:00000044-a-1#6687,NA,NA,p.Gln168Glu,-0.92,-0.98,1,Q498E +urn:mavedb:00000044-a-1#6689,NA,NA,p.Gln168Phe,0.17,0.15,1,Q498F +urn:mavedb:00000044-a-1#6690,NA,NA,p.Gln168Phe,0.12,0.15,2,Q498F +urn:mavedb:00000044-a-1#6666,NA,NA,p.Phe167Gln,-4.84,-4.75,2,F497Q +urn:mavedb:00000044-a-1#6715,NA,NA,p.Gln168Trp,0,0.07,1,Q498W +urn:mavedb:00000044-a-1#6667,NA,NA,p.Phe167Arg,-4.76,-4.8,1,F497R +urn:mavedb:00000044-a-1#6669,NA,NA,p.Phe167Ser,-4.76,-4.8,1,F497S +urn:mavedb:00000044-a-1#6693,NA,NA,p.Gln168His,0.3,0.3,1,Q498H +urn:mavedb:00000044-a-1#6694,NA,NA,p.Gln168His,0.31,0.3,2,Q498H +urn:mavedb:00000044-a-1#6670,NA,NA,p.Phe167Ser,-4.84,-4.8,2,F497S +urn:mavedb:00000044-a-1#6695,NA,NA,p.Gln168Ile,-1.43,-1.48,1,Q498I +urn:mavedb:00000044-a-1#6696,NA,NA,p.Gln168Ile,-1.53,-1.48,2,Q498I +urn:mavedb:00000044-a-1#6672,NA,NA,p.Phe167Thr,-4.84,-4.8,2,F497T +urn:mavedb:00000044-a-1#6673,NA,NA,p.Phe167Val,-4.64,-4.73,1,F497V +urn:mavedb:00000044-a-1#6700,NA,NA,p.Gln168Leu,-1.65,-1.58,2,Q498L +urn:mavedb:00000044-a-1#6701,NA,NA,p.Gln168Met,-0.42,-0.51,1,Q498M +urn:mavedb:00000044-a-1#6702,NA,NA,p.Gln168Met,-0.6,-0.51,2,Q498M +urn:mavedb:00000044-a-1#6703,NA,NA,p.Gln168Asn,-0.45,-0.5,1,Q498N +urn:mavedb:00000044-a-1#6704,NA,NA,p.Gln168Asn,-0.55,-0.5,2,Q498N +urn:mavedb:00000044-a-1#6705,NA,NA,p.Gln168Pro,-2.74,-3.14,1,Q498P +urn:mavedb:00000044-a-1#6718,NA,NA,p.Gln168Tyr,0.3,0.16,2,Q498Y +urn:mavedb:00000044-a-1#6719,NA,NA,p.Gln168*,NA,NA,1,Q498 +urn:mavedb:00000044-a-1#6720,NA,NA,p.Gln168*,NA,NA,2,Q498 +urn:mavedb:00000044-a-1#6721,NA,NA,p.Pro169Ala,-0.44,-0.47,1,P499A +urn:mavedb:00000044-a-1#6722,NA,NA,p.Pro169Ala,-0.51,-0.47,2,P499A +urn:mavedb:00000044-a-1#6747,NA,NA,p.Pro169Arg,-0.11,-0.14,1,P499R +urn:mavedb:00000044-a-1#6749,NA,NA,p.Pro169Ser,-0.18,-0.23,1,P499S +urn:mavedb:00000044-a-1#6750,NA,NA,p.Pro169Ser,-0.28,-0.23,2,P499S +urn:mavedb:00000044-a-1#6757,NA,NA,p.Pro169Tyr,-0.34,-0.36,1,P499Y +urn:mavedb:00000044-a-1#6758,NA,NA,p.Pro169Tyr,-0.4,-0.36,2,P499Y +urn:mavedb:00000044-a-1#6760,NA,NA,p.Pro169*,NA,NA,2,P499 +urn:mavedb:00000044-a-1#6761,NA,NA,p.Thr170Ala,-0.54,-0.56,1,T500A +urn:mavedb:00000044-a-1#6762,NA,NA,p.Thr170Ala,-0.58,-0.56,2,T500A +urn:mavedb:00000044-a-1#6763,NA,NA,p.Thr170Cys,-1.48,-1.6,1,T500C +urn:mavedb:00000044-a-1#6764,NA,NA,p.Thr170Cys,-1.72,-1.6,2,T500C +urn:mavedb:00000044-a-1#6765,NA,NA,p.Thr170Asp,-1.95,-1.99,1,T500D +urn:mavedb:00000044-a-1#6766,NA,NA,p.Thr170Asp,-2.03,-1.99,2,T500D +urn:mavedb:00000044-a-1#6767,NA,NA,p.Thr170Glu,-1.27,-1.14,1,T500E +urn:mavedb:00000044-a-1#6768,NA,NA,p.Thr170Glu,-1.01,-1.14,2,T500E +urn:mavedb:00000044-a-1#6769,NA,NA,p.Thr170Phe,-0.92,-0.98,1,T500F +urn:mavedb:00000044-a-1#6770,NA,NA,p.Thr170Phe,-1.05,-0.98,2,T500F +urn:mavedb:00000044-a-1#6771,NA,NA,p.Thr170Gly,-0.84,-0.93,1,T500G +urn:mavedb:00000044-a-1#6772,NA,NA,p.Thr170Gly,-1.02,-0.93,2,T500G +urn:mavedb:00000044-a-1#6773,NA,NA,p.Thr170His,-0.84,-0.88,1,T500H +urn:mavedb:00000044-a-1#6774,NA,NA,p.Thr170His,-0.93,-0.88,2,T500H +urn:mavedb:00000044-a-1#6775,NA,NA,p.Thr170Ile,-2.27,-2.3,1,T500I +urn:mavedb:00000044-a-1#6776,NA,NA,p.Thr170Ile,-2.32,-2.3,2,T500I +urn:mavedb:00000044-a-1#6777,NA,NA,p.Thr170Lys,-0.8,-0.8,1,T500K +urn:mavedb:00000044-a-1#6778,NA,NA,p.Thr170Lys,-0.8,-0.8,2,T500K +urn:mavedb:00000044-a-1#6779,NA,NA,p.Thr170Leu,-1.44,-1.52,1,T500L +urn:mavedb:00000044-a-1#6780,NA,NA,p.Thr170Leu,-1.59,-1.52,2,T500L +urn:mavedb:00000044-a-1#6781,NA,NA,p.Thr170Met,-0.69,-0.75,1,T500M +urn:mavedb:00000044-a-1#6782,NA,NA,p.Thr170Met,-0.8,-0.75,2,T500M +urn:mavedb:00000044-a-1#6783,NA,NA,p.Thr170Asn,-1.12,-1.2,1,T500N +urn:mavedb:00000044-a-1#6784,NA,NA,p.Thr170Asn,-1.28,-1.2,2,T500N +urn:mavedb:00000044-a-1#6785,NA,NA,p.Thr170Pro,-1.01,-1.12,1,T500P +urn:mavedb:00000044-a-1#6786,NA,NA,p.Thr170Pro,-1.24,-1.12,2,T500P +urn:mavedb:00000044-a-1#6787,NA,NA,p.Thr170Gln,-0.42,-0.44,1,T500Q +urn:mavedb:00000044-a-1#6788,NA,NA,p.Thr170Gln,-0.46,-0.44,2,T500Q +urn:mavedb:00000044-a-1#6789,NA,NA,p.Thr170Arg,-1.08,-1.12,1,T500R +urn:mavedb:00000044-a-1#6790,NA,NA,p.Thr170Arg,-1.16,-1.12,2,T500R +urn:mavedb:00000044-a-1#6791,NA,NA,p.Thr170Ser,-0.32,-0.32,1,T500S +urn:mavedb:00000044-a-1#6792,NA,NA,p.Thr170Ser,-0.33,-0.32,2,T500S +urn:mavedb:00000044-a-1#6793,NA,NA,p.Thr170Val,-1.79,-1.89,1,T500V +urn:mavedb:00000044-a-1#6794,NA,NA,p.Thr170Val,-1.99,-1.89,2,T500V +urn:mavedb:00000044-a-1#6795,NA,NA,p.Thr170Trp,-0.34,-0.43,1,T500W +urn:mavedb:00000044-a-1#6796,NA,NA,p.Thr170Trp,-0.52,-0.43,2,T500W +urn:mavedb:00000044-a-1#6797,NA,NA,p.Thr170Tyr,-0.87,-0.97,1,T500Y +urn:mavedb:00000044-a-1#6798,NA,NA,p.Thr170Tyr,-1.07,-0.97,2,T500Y +urn:mavedb:00000044-a-1#6799,NA,NA,p.Thr170*,NA,NA,1,T500 +urn:mavedb:00000044-a-1#6800,NA,NA,p.Thr170*,NA,NA,2,T500 +urn:mavedb:00000044-a-1#6801,NA,NA,p.Asn171Ala,-0.02,-0.06,1,N501A +urn:mavedb:00000044-a-1#6802,NA,NA,p.Asn171Ala,-0.1,-0.06,2,N501A +urn:mavedb:00000044-a-1#6803,NA,NA,p.Asn171Cys,-0.6,-0.58,1,N501C +urn:mavedb:00000044-a-1#6804,NA,NA,p.Asn171Cys,-0.57,-0.58,2,N501C +urn:mavedb:00000044-a-1#6805,NA,NA,p.Asn171Asp,-2.4,-2.42,1,N501D +urn:mavedb:00000044-a-1#6806,NA,NA,p.Asn171Asp,-2.44,-2.42,2,N501D 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+urn:mavedb:00000044-a-1#6990,NA,NA,p.Tyr175Arg,-2.47,-2.47,2,Y505R +urn:mavedb:00000044-a-1#6991,NA,NA,p.Tyr175Ser,-2.35,-2.37,1,Y505S +urn:mavedb:00000044-a-1#6992,NA,NA,p.Tyr175Ser,-2.39,-2.37,2,Y505S +urn:mavedb:00000044-a-1#6993,NA,NA,p.Tyr175Thr,-3.46,-3.46,1,Y505T +urn:mavedb:00000044-a-1#6994,NA,NA,p.Tyr175Thr,-3.46,-3.46,2,Y505T +urn:mavedb:00000044-a-1#6995,NA,NA,p.Tyr175Val,-2.46,-2.46,1,Y505V +urn:mavedb:00000044-a-1#6996,NA,NA,p.Tyr175Val,-2.46,-2.46,2,Y505V +urn:mavedb:00000044-a-1#6997,NA,NA,p.Tyr175Trp,0.12,0.13,1,Y505W +urn:mavedb:00000044-a-1#6998,NA,NA,p.Tyr175Trp,0.14,0.13,2,Y505W +urn:mavedb:00000044-a-1#6999,NA,NA,p.Tyr175*,NA,NA,1,Y505 +urn:mavedb:00000044-a-1#7000,NA,NA,p.Tyr175*,NA,NA,2,Y505 +urn:mavedb:00000044-a-1#7001,NA,NA,p.Gln176Ala,-1.42,-1.45,1,Q506A +urn:mavedb:00000044-a-1#7002,NA,NA,p.Gln176Ala,-1.48,-1.45,2,Q506A +urn:mavedb:00000044-a-1#7003,NA,NA,p.Gln176Cys,-2.1,-2.07,1,Q506C +urn:mavedb:00000044-a-1#7004,NA,NA,p.Gln176Cys,-2.04,-2.07,2,Q506C +urn:mavedb:00000044-a-1#7005,NA,NA,p.Gln176Asp,-2.53,-2.64,1,Q506D +urn:mavedb:00000044-a-1#7006,NA,NA,p.Gln176Asp,-2.75,-2.64,2,Q506D +urn:mavedb:00000044-a-1#7007,NA,NA,p.Gln176Glu,-2.19,-2.2,1,Q506E +urn:mavedb:00000044-a-1#7008,NA,NA,p.Gln176Glu,-2.21,-2.2,2,Q506E +urn:mavedb:00000044-a-1#7009,NA,NA,p.Gln176Phe,-2.66,-2.78,1,Q506F +urn:mavedb:00000044-a-1#7010,NA,NA,p.Gln176Phe,-2.9,-2.78,2,Q506F +urn:mavedb:00000044-a-1#7056,NA,NA,p.Pro177Ile,-4.84,-4.68,2,P507I +urn:mavedb:00000044-a-1#7057,NA,NA,p.Pro177Lys,-4.76,-4.8,1,P507K +urn:mavedb:00000044-a-1#7058,NA,NA,p.Pro177Lys,-4.84,-4.8,2,P507K +urn:mavedb:00000044-a-1#7059,NA,NA,p.Pro177Leu,-4.76,-4.8,1,P507L +urn:mavedb:00000044-a-1#7060,NA,NA,p.Pro177Leu,-4.84,-4.8,2,P507L +urn:mavedb:00000044-a-1#7061,NA,NA,p.Pro177Met,-4.69,-4.43,1,P507M +urn:mavedb:00000044-a-1#7062,NA,NA,p.Pro177Met,-4.17,-4.43,2,P507M +urn:mavedb:00000044-a-1#7063,NA,NA,p.Pro177Asn,-4.76,-4.8,1,P507N +urn:mavedb:00000044-a-1#7064,NA,NA,p.Pro177Asn,-4.84,-4.8,2,P507N +urn:mavedb:00000044-a-1#7065,NA,NA,p.Pro177Gln,-4.76,-4.61,1,P507Q +urn:mavedb:00000044-a-1#7066,NA,NA,p.Pro177Gln,-4.45,-4.61,2,P507Q +urn:mavedb:00000044-a-1#7067,NA,NA,p.Pro177Arg,-4.76,-4.8,1,P507R +urn:mavedb:00000044-a-1#7068,NA,NA,p.Pro177Arg,-4.84,-4.8,2,P507R +urn:mavedb:00000044-a-1#7069,NA,NA,p.Pro177Ser,-1.21,-1.29,1,P507S +urn:mavedb:00000044-a-1#7070,NA,NA,p.Pro177Ser,-1.38,-1.29,2,P507S +urn:mavedb:00000044-a-1#7071,NA,NA,p.Pro177Thr,-4.33,-4.45,1,P507T +urn:mavedb:00000044-a-1#7072,NA,NA,p.Pro177Thr,-4.58,-4.45,2,P507T +urn:mavedb:00000044-a-1#7073,NA,NA,p.Pro177Val,-4.12,-4.31,1,P507V +urn:mavedb:00000044-a-1#7074,NA,NA,p.Pro177Val,-4.51,-4.31,2,P507V +urn:mavedb:00000044-a-1#7075,NA,NA,p.Pro177Trp,-4.76,-4.61,1,P507W +urn:mavedb:00000044-a-1#7076,NA,NA,p.Pro177Trp,-4.47,-4.61,2,P507W +urn:mavedb:00000044-a-1#7077,NA,NA,p.Pro177Tyr,-4.76,-4.8,1,P507Y +urn:mavedb:00000044-a-1#7078,NA,NA,p.Pro177Tyr,-4.84,-4.8,2,P507Y +urn:mavedb:00000044-a-1#7079,NA,NA,p.Pro177*,NA,NA,1,P507 +urn:mavedb:00000044-a-1#7080,NA,NA,p.Pro177*,NA,NA,2,P507 +urn:mavedb:00000044-a-1#7081,NA,NA,p.Tyr178Ala,-0.39,-0.4,1,Y508A +urn:mavedb:00000044-a-1#7082,NA,NA,p.Tyr178Ala,-0.42,-0.4,2,Y508A +urn:mavedb:00000044-a-1#7083,NA,NA,p.Tyr178Cys,-0.35,-0.33,1,Y508C +urn:mavedb:00000044-a-1#7084,NA,NA,p.Tyr178Cys,-0.32,-0.33,2,Y508C +urn:mavedb:00000044-a-1#7085,NA,NA,p.Tyr178Asp,-3.92,-3.08,1,Y508D +urn:mavedb:00000044-a-1#7086,NA,NA,p.Tyr178Asp,-2.25,-3.08,2,Y508D +urn:mavedb:00000044-a-1#7087,NA,NA,p.Tyr178Glu,-1.02,-1.14,1,Y508E +urn:mavedb:00000044-a-1#7088,NA,NA,p.Tyr178Glu,-1.25,-1.14,2,Y508E +urn:mavedb:00000044-a-1#7089,NA,NA,p.Tyr178Phe,0,0.02,1,Y508F +urn:mavedb:00000044-a-1#7090,NA,NA,p.Tyr178Phe,0.04,0.02,2,Y508F +urn:mavedb:00000044-a-1#7091,NA,NA,p.Tyr178Gly,-4.76,-4.7,1,Y508G +urn:mavedb:00000044-a-1#7092,NA,NA,p.Tyr178Gly,-4.64,-4.7,2,Y508G +urn:mavedb:00000044-a-1#7011,NA,NA,p.Gln176Gly,-2.28,-2.37,1,Q506G +urn:mavedb:00000044-a-1#7012,NA,NA,p.Gln176Gly,-2.46,-2.37,2,Q506G +urn:mavedb:00000044-a-1#7013,NA,NA,p.Gln176His,-0.74,-0.84,1,Q506H +urn:mavedb:00000044-a-1#7014,NA,NA,p.Gln176His,-0.93,-0.84,2,Q506H +urn:mavedb:00000044-a-1#7015,NA,NA,p.Gln176Ile,-2.5,-2.53,1,Q506I +urn:mavedb:00000044-a-1#7016,NA,NA,p.Gln176Ile,-2.55,-2.53,2,Q506I +urn:mavedb:00000044-a-1#7017,NA,NA,p.Gln176Lys,-1.36,-1.46,1,Q506K +urn:mavedb:00000044-a-1#7018,NA,NA,p.Gln176Lys,-1.55,-1.46,2,Q506K +urn:mavedb:00000044-a-1#7020,NA,NA,p.Gln176Leu,-1.55,-1.46,2,Q506L +urn:mavedb:00000044-a-1#7021,NA,NA,p.Gln176Met,-0.53,-0.57,1,Q506M +urn:mavedb:00000044-a-1#7022,NA,NA,p.Gln176Met,-0.61,-0.57,2,Q506M +urn:mavedb:00000044-a-1#7023,NA,NA,p.Gln176Asn,-0.25,-0.28,1,Q506N +urn:mavedb:00000044-a-1#7024,NA,NA,p.Gln176Asn,-0.31,-0.28,2,Q506N +urn:mavedb:00000044-a-1#7025,NA,NA,p.Gln176Pro,-4.75,-4.8,1,Q506P +urn:mavedb:00000044-a-1#7026,NA,NA,p.Gln176Pro,-4.84,-4.8,2,Q506P +urn:mavedb:00000044-a-1#7027,NA,NA,p.Gln176Arg,-1.53,-1.62,1,Q506R +urn:mavedb:00000044-a-1#7028,NA,NA,p.Gln176Arg,-1.72,-1.62,2,Q506R +urn:mavedb:00000044-a-1#7029,NA,NA,p.Gln176Ser,-1.49,-1.57,1,Q506S +urn:mavedb:00000044-a-1#7030,NA,NA,p.Gln176Ser,-1.64,-1.57,2,Q506S +urn:mavedb:00000044-a-1#7031,NA,NA,p.Gln176Thr,-2.18,-2.29,1,Q506T +urn:mavedb:00000044-a-1#7032,NA,NA,p.Gln176Thr,-2.4,-2.29,2,Q506T +urn:mavedb:00000044-a-1#7033,NA,NA,p.Gln176Val,-2.25,-2.32,1,Q506V +urn:mavedb:00000044-a-1#7034,NA,NA,p.Gln176Val,-2.4,-2.32,2,Q506V +urn:mavedb:00000044-a-1#7035,NA,NA,p.Gln176Trp,-2.24,-2.29,1,Q506W +urn:mavedb:00000044-a-1#7036,NA,NA,p.Gln176Trp,-2.35,-2.29,2,Q506W +urn:mavedb:00000044-a-1#7037,NA,NA,p.Gln176Tyr,-2.81,-2.86,1,Q506Y +urn:mavedb:00000044-a-1#7038,NA,NA,p.Gln176Tyr,-2.91,-2.86,2,Q506Y +urn:mavedb:00000044-a-1#7039,NA,NA,p.Gln176*,NA,NA,1,Q506 +urn:mavedb:00000044-a-1#7040,NA,NA,p.Gln176*,NA,NA,2,Q506 +urn:mavedb:00000044-a-1#7041,NA,NA,p.Pro177Ala,-0.68,-0.75,1,P507A +urn:mavedb:00000044-a-1#7042,NA,NA,p.Pro177Ala,-0.82,-0.75,2,P507A +urn:mavedb:00000044-a-1#7043,NA,NA,p.Pro177Cys,-1.98,-2.31,1,P507C +urn:mavedb:00000044-a-1#7044,NA,NA,p.Pro177Cys,-2.63,-2.31,2,P507C +urn:mavedb:00000044-a-1#7045,NA,NA,p.Pro177Asp,-4.32,-4.13,1,P507D +urn:mavedb:00000044-a-1#7046,NA,NA,p.Pro177Asp,-3.94,-4.13,2,P507D +urn:mavedb:00000044-a-1#7047,NA,NA,p.Pro177Glu,-4.76,-4.8,1,P507E +urn:mavedb:00000044-a-1#7048,NA,NA,p.Pro177Glu,-4.84,-4.8,2,P507E +urn:mavedb:00000044-a-1#7049,NA,NA,p.Pro177Phe,-4.76,-4.8,1,P507F +urn:mavedb:00000044-a-1#7050,NA,NA,p.Pro177Phe,-4.84,-4.8,2,P507F +urn:mavedb:00000044-a-1#7051,NA,NA,p.Pro177Gly,-3.13,-3.07,1,P507G +urn:mavedb:00000044-a-1#7052,NA,NA,p.Pro177Gly,-3.01,-3.07,2,P507G +urn:mavedb:00000044-a-1#7053,NA,NA,p.Pro177His,-4.28,-4.41,1,P507H +urn:mavedb:00000044-a-1#7054,NA,NA,p.Pro177His,-4.54,-4.41,2,P507H +urn:mavedb:00000044-a-1#7055,NA,NA,p.Pro177Ile,-4.52,-4.68,1,P507I +urn:mavedb:00000044-a-1#7121,NA,NA,p.Arg179Ala,-3.72,-4.15,1,R509A +urn:mavedb:00000044-a-1#7122,NA,NA,p.Arg179Ala,-4.58,-4.15,2,R509A +urn:mavedb:00000044-a-1#7123,NA,NA,p.Arg179Cys,-3.37,-3.7,1,R509C +urn:mavedb:00000044-a-1#7124,NA,NA,p.Arg179Cys,-4.03,-3.7,2,R509C +urn:mavedb:00000044-a-1#7125,NA,NA,p.Arg179Asp,-4.76,-4.8,1,R509D +urn:mavedb:00000044-a-1#7126,NA,NA,p.Arg179Asp,-4.84,-4.8,2,R509D +urn:mavedb:00000044-a-1#7127,NA,NA,p.Arg179Glu,-4.76,-4.8,1,R509E +urn:mavedb:00000044-a-1#7128,NA,NA,p.Arg179Glu,-4.84,-4.8,2,R509E +urn:mavedb:00000044-a-1#7129,NA,NA,p.Arg179Phe,-4.46,-4.65,1,R509F +urn:mavedb:00000044-a-1#7130,NA,NA,p.Arg179Phe,-4.84,-4.65,2,R509F +urn:mavedb:00000044-a-1#7131,NA,NA,p.Arg179Gly,-4.76,-4.8,1,R509G +urn:mavedb:00000044-a-1#7132,NA,NA,p.Arg179Gly,-4.84,-4.8,2,R509G +urn:mavedb:00000044-a-1#7133,NA,NA,p.Arg179His,-0.76,-1,1,R509H +urn:mavedb:00000044-a-1#7134,NA,NA,p.Arg179His,-1.23,-1,2,R509H +urn:mavedb:00000044-a-1#7135,NA,NA,p.Arg179Ile,-3.68,-3.76,1,R509I +urn:mavedb:00000044-a-1#7136,NA,NA,p.Arg179Ile,-3.84,-3.76,2,R509I +urn:mavedb:00000044-a-1#7137,NA,NA,p.Arg179Lys,-1.03,-1.11,1,R509K +urn:mavedb:00000044-a-1#7138,NA,NA,p.Arg179Lys,-1.19,-1.11,2,R509K +urn:mavedb:00000044-a-1#7139,NA,NA,p.Arg179Leu,-4.64,-4.74,1,R509L +urn:mavedb:00000044-a-1#7140,NA,NA,p.Arg179Leu,-4.84,-4.74,2,R509L +urn:mavedb:00000044-a-1#7141,NA,NA,p.Arg179Met,-4.71,-4.74,1,R509M +urn:mavedb:00000044-a-1#7142,NA,NA,p.Arg179Met,-4.78,-4.74,2,R509M +urn:mavedb:00000044-a-1#7143,NA,NA,p.Arg179Asn,-4.73,-4.7,1,R509N +urn:mavedb:00000044-a-1#7144,NA,NA,p.Arg179Asn,-4.67,-4.7,2,R509N +urn:mavedb:00000044-a-1#7145,NA,NA,p.Arg179Pro,-4.61,-4.72,1,R509P +urn:mavedb:00000044-a-1#7146,NA,NA,p.Arg179Pro,-4.84,-4.72,2,R509P +urn:mavedb:00000044-a-1#7147,NA,NA,p.Arg179Gln,-3.29,-3.21,1,R509Q +urn:mavedb:00000044-a-1#7148,NA,NA,p.Arg179Gln,-3.13,-3.21,2,R509Q +urn:mavedb:00000044-a-1#7093,NA,NA,p.Tyr178His,0.1,0.07,1,Y508H +urn:mavedb:00000044-a-1#7094,NA,NA,p.Tyr178His,0.05,0.07,2,Y508H +urn:mavedb:00000044-a-1#7095,NA,NA,p.Tyr178Ile,-0.56,-0.57,1,Y508I +urn:mavedb:00000044-a-1#7096,NA,NA,p.Tyr178Ile,-0.58,-0.57,2,Y508I +urn:mavedb:00000044-a-1#7097,NA,NA,p.Tyr178Lys,-1.1,-1.23,1,Y508K +urn:mavedb:00000044-a-1#7098,NA,NA,p.Tyr178Lys,-1.36,-1.23,2,Y508K +urn:mavedb:00000044-a-1#7099,NA,NA,p.Tyr178Leu,-0.48,-0.52,1,Y508L +urn:mavedb:00000044-a-1#7100,NA,NA,p.Tyr178Leu,-0.56,-0.52,2,Y508L +urn:mavedb:00000044-a-1#7101,NA,NA,p.Tyr178Met,-0.18,-0.18,1,Y508M +urn:mavedb:00000044-a-1#7102,NA,NA,p.Tyr178Met,-0.19,-0.18,2,Y508M +urn:mavedb:00000044-a-1#7103,NA,NA,p.Tyr178Asn,-0.17,-0.19,1,Y508N +urn:mavedb:00000044-a-1#7104,NA,NA,p.Tyr178Asn,-0.2,-0.19,2,Y508N +urn:mavedb:00000044-a-1#7105,NA,NA,p.Tyr178Pro,-4.76,-4.68,1,Y508P +urn:mavedb:00000044-a-1#7106,NA,NA,p.Tyr178Pro,-4.61,-4.68,2,Y508P +urn:mavedb:00000044-a-1#7107,NA,NA,p.Tyr178Gln,-0.32,-0.38,1,Y508Q +urn:mavedb:00000044-a-1#7108,NA,NA,p.Tyr178Gln,-0.44,-0.38,2,Y508Q +urn:mavedb:00000044-a-1#7109,NA,NA,p.Tyr178Arg,-0.72,-0.77,1,Y508R +urn:mavedb:00000044-a-1#7110,NA,NA,p.Tyr178Arg,-0.82,-0.77,2,Y508R +urn:mavedb:00000044-a-1#7111,NA,NA,p.Tyr178Ser,-0.39,-0.4,1,Y508S +urn:mavedb:00000044-a-1#7112,NA,NA,p.Tyr178Ser,-0.41,-0.4,2,Y508S +urn:mavedb:00000044-a-1#7113,NA,NA,p.Tyr178Thr,-0.26,-0.27,1,Y508T +urn:mavedb:00000044-a-1#7114,NA,NA,p.Tyr178Thr,-0.28,-0.27,2,Y508T +urn:mavedb:00000044-a-1#7115,NA,NA,p.Tyr178Val,-0.19,-0.25,1,Y508V +urn:mavedb:00000044-a-1#7116,NA,NA,p.Tyr178Val,-0.3,-0.25,2,Y508V +urn:mavedb:00000044-a-1#7117,NA,NA,p.Tyr178Trp,-0.12,-0.17,1,Y508W +urn:mavedb:00000044-a-1#7118,NA,NA,p.Tyr178Trp,-0.23,-0.17,2,Y508W +urn:mavedb:00000044-a-1#7119,NA,NA,p.Tyr178*,NA,NA,1,Y508 +urn:mavedb:00000044-a-1#7120,NA,NA,p.Tyr178*,NA,NA,2,Y508 +urn:mavedb:00000044-a-1#7152,NA,NA,p.Arg179Thr,-2.44,-2.06,2,R509T +urn:mavedb:00000044-a-1#7153,NA,NA,p.Arg179Val,-2.43,-2.49,1,R509V +urn:mavedb:00000044-a-1#7154,NA,NA,p.Arg179Val,-2.55,-2.49,2,R509V +urn:mavedb:00000044-a-1#7155,NA,NA,p.Arg179Trp,-4.76,-4.8,1,R509W +urn:mavedb:00000044-a-1#7156,NA,NA,p.Arg179Trp,-4.84,-4.8,2,R509W +urn:mavedb:00000044-a-1#7157,NA,NA,p.Arg179Tyr,-4.76,-4.8,1,R509Y +urn:mavedb:00000044-a-1#7187,NA,NA,p.Val180Gln,-4.36,-4.6,1,V510Q +urn:mavedb:00000044-a-1#7158,NA,NA,p.Arg179Tyr,-4.84,-4.8,2,R509Y +urn:mavedb:00000044-a-1#7159,NA,NA,p.Arg179*,NA,NA,1,R509 +urn:mavedb:00000044-a-1#7160,NA,NA,p.Arg179*,NA,NA,2,R509 +urn:mavedb:00000044-a-1#7161,NA,NA,p.Val180Ala,-0.75,-0.83,1,V510A +urn:mavedb:00000044-a-1#7162,NA,NA,p.Val180Ala,-0.9,-0.83,2,V510A +urn:mavedb:00000044-a-1#7163,NA,NA,p.Val180Cys,-0.16,-0.14,1,V510C +urn:mavedb:00000044-a-1#7164,NA,NA,p.Val180Cys,-0.12,-0.14,2,V510C +urn:mavedb:00000044-a-1#7165,NA,NA,p.Val180Asp,-4.76,-4.8,1,V510D +urn:mavedb:00000044-a-1#7166,NA,NA,p.Val180Asp,-4.84,-4.8,2,V510D +urn:mavedb:00000044-a-1#7167,NA,NA,p.Val180Glu,-4.35,-3.61,1,V510E +urn:mavedb:00000044-a-1#7168,NA,NA,p.Val180Glu,-2.87,-3.61,2,V510E +urn:mavedb:00000044-a-1#7169,NA,NA,p.Val180Phe,-1.62,-1.77,1,V510F +urn:mavedb:00000044-a-1#7170,NA,NA,p.Val180Phe,-1.92,-1.77,2,V510F +urn:mavedb:00000044-a-1#7171,NA,NA,p.Val180Gly,-4.76,-4.8,1,V510G +urn:mavedb:00000044-a-1#7172,NA,NA,p.Val180Gly,-4.84,-4.8,2,V510G +urn:mavedb:00000044-a-1#7173,NA,NA,p.Val180His,-3.63,-3.88,1,V510H +urn:mavedb:00000044-a-1#7174,NA,NA,p.Val180His,-4.13,-3.88,2,V510H +urn:mavedb:00000044-a-1#7175,NA,NA,p.Val180Ile,-0.13,-0.16,1,V510I +urn:mavedb:00000044-a-1#7176,NA,NA,p.Val180Ile,-0.2,-0.16,2,V510I +urn:mavedb:00000044-a-1#7177,NA,NA,p.Val180Lys,-4.76,-4.56,1,V510K +urn:mavedb:00000044-a-1#7178,NA,NA,p.Val180Lys,-4.37,-4.56,2,V510K +urn:mavedb:00000044-a-1#7179,NA,NA,p.Val180Leu,-0.58,-0.6,1,V510L +urn:mavedb:00000044-a-1#7180,NA,NA,p.Val180Leu,-0.63,-0.6,2,V510L +urn:mavedb:00000044-a-1#7181,NA,NA,p.Val180Met,-0.5,-0.53,1,V510M +urn:mavedb:00000044-a-1#7182,NA,NA,p.Val180Met,-0.57,-0.53,2,V510M +urn:mavedb:00000044-a-1#7183,NA,NA,p.Val180Asn,-4.16,-4.5,1,V510N +urn:mavedb:00000044-a-1#7184,NA,NA,p.Val180Asn,-4.84,-4.5,2,V510N +urn:mavedb:00000044-a-1#7185,NA,NA,p.Val180Pro,-4.21,-4.53,1,V510P +urn:mavedb:00000044-a-1#7186,NA,NA,p.Val180Pro,-4.84,-4.53,2,V510P +urn:mavedb:00000044-a-1#7188,NA,NA,p.Val180Gln,-4.84,-4.6,2,V510Q +urn:mavedb:00000044-a-1#7189,NA,NA,p.Val180Arg,-3.95,-4.39,1,V510R +urn:mavedb:00000044-a-1#7190,NA,NA,p.Val180Arg,-4.84,-4.39,2,V510R +urn:mavedb:00000044-a-1#7191,NA,NA,p.Val180Ser,-4,-4.42,1,V510S +urn:mavedb:00000044-a-1#7192,NA,NA,p.Val180Ser,-4.84,-4.42,2,V510S +urn:mavedb:00000044-a-1#7193,NA,NA,p.Val180Thr,-0.44,-0.47,1,V510T +urn:mavedb:00000044-a-1#7194,NA,NA,p.Val180Thr,-0.51,-0.47,2,V510T +urn:mavedb:00000044-a-1#7223,NA,NA,p.Val181Asn,-4.12,-3.81,1,V511N +urn:mavedb:00000044-a-1#7195,NA,NA,p.Val180Trp,-4.76,-4.35,1,V510W +urn:mavedb:00000044-a-1#7196,NA,NA,p.Val180Trp,-3.94,-4.35,2,V510W +urn:mavedb:00000044-a-1#7197,NA,NA,p.Val180Tyr,-4.76,-4.6,1,V510Y +urn:mavedb:00000044-a-1#7198,NA,NA,p.Val180Tyr,-4.45,-4.6,2,V510Y +urn:mavedb:00000044-a-1#7199,NA,NA,p.Val180*,NA,NA,1,V510 +urn:mavedb:00000044-a-1#7200,NA,NA,p.Val180*,NA,NA,2,V510 +urn:mavedb:00000044-a-1#7201,NA,NA,p.Val181Ala,-0.74,-0.78,1,V511A +urn:mavedb:00000044-a-1#7202,NA,NA,p.Val181Ala,-0.82,-0.78,2,V511A +urn:mavedb:00000044-a-1#7203,NA,NA,p.Val181Cys,-0.67,-0.65,1,V511C +urn:mavedb:00000044-a-1#7204,NA,NA,p.Val181Cys,-0.64,-0.65,2,V511C +urn:mavedb:00000044-a-1#7205,NA,NA,p.Val181Asp,-4.25,-4.46,1,V511D +urn:mavedb:00000044-a-1#7206,NA,NA,p.Val181Asp,-4.67,-4.46,2,V511D +urn:mavedb:00000044-a-1#7207,NA,NA,p.Val181Glu,-4.12,-4.04,1,V511E +urn:mavedb:00000044-a-1#7208,NA,NA,p.Val181Glu,-3.96,-4.04,2,V511E +urn:mavedb:00000044-a-1#7209,NA,NA,p.Val181Phe,-1.84,-1.8,1,V511F +urn:mavedb:00000044-a-1#7210,NA,NA,p.Val181Phe,-1.76,-1.8,2,V511F +urn:mavedb:00000044-a-1#7211,NA,NA,p.Val181Gly,-4.76,-4.8,1,V511G +urn:mavedb:00000044-a-1#7212,NA,NA,p.Val181Gly,-4.84,-4.8,2,V511G +urn:mavedb:00000044-a-1#7213,NA,NA,p.Val181His,-3.46,-3.32,1,V511H +urn:mavedb:00000044-a-1#7214,NA,NA,p.Val181His,-3.18,-3.32,2,V511H +urn:mavedb:00000044-a-1#7215,NA,NA,p.Val181Ile,-0.34,-0.4,1,V511I +urn:mavedb:00000044-a-1#7216,NA,NA,p.Val181Ile,-0.46,-0.4,2,V511I +urn:mavedb:00000044-a-1#7217,NA,NA,p.Val181Lys,-4.76,-4.8,1,V511K +urn:mavedb:00000044-a-1#7218,NA,NA,p.Val181Lys,-4.84,-4.8,2,V511K +urn:mavedb:00000044-a-1#7219,NA,NA,p.Val181Leu,-0.74,-0.83,1,V511L +urn:mavedb:00000044-a-1#7220,NA,NA,p.Val181Leu,-0.92,-0.83,2,V511L +urn:mavedb:00000044-a-1#7221,NA,NA,p.Val181Met,-0.84,-0.85,1,V511M +urn:mavedb:00000044-a-1#7222,NA,NA,p.Val181Met,-0.87,-0.85,2,V511M +urn:mavedb:00000044-a-1#7224,NA,NA,p.Val181Asn,-3.51,-3.81,2,V511N +urn:mavedb:00000044-a-1#7225,NA,NA,p.Val181Pro,-4.34,-4.19,1,V511P +urn:mavedb:00000044-a-1#7226,NA,NA,p.Val181Pro,-4.04,-4.19,2,V511P +urn:mavedb:00000044-a-1#7227,NA,NA,p.Val181Gln,-4.02,-2.99,1,V511Q +urn:mavedb:00000044-a-1#7228,NA,NA,p.Val181Gln,-1.96,-2.99,2,V511Q +urn:mavedb:00000044-a-1#7229,NA,NA,p.Val181Arg,-4.76,-4.8,1,V511R +urn:mavedb:00000044-a-1#7230,NA,NA,p.Val181Arg,-4.84,-4.8,2,V511R +urn:mavedb:00000044-a-1#7231,NA,NA,p.Val181Ser,-3.6,-3.42,1,V511S +urn:mavedb:00000044-a-1#7232,NA,NA,p.Val181Ser,-3.24,-3.42,2,V511S +urn:mavedb:00000044-a-1#7233,NA,NA,p.Val181Thr,-0.8,-0.89,1,V511T +urn:mavedb:00000044-a-1#7234,NA,NA,p.Val181Thr,-0.99,-0.89,2,V511T +urn:mavedb:00000044-a-1#7235,NA,NA,p.Val181Trp,-2.13,-3.2,1,V511W +urn:mavedb:00000044-a-1#7236,NA,NA,p.Val181Trp,-4.28,-3.2,2,V511W +urn:mavedb:00000044-a-1#7237,NA,NA,p.Val181Tyr,-2.69,-2.27,1,V511Y +urn:mavedb:00000044-a-1#7238,NA,NA,p.Val181Tyr,-1.84,-2.27,2,V511Y +urn:mavedb:00000044-a-1#7239,NA,NA,p.Val181*,NA,NA,1,V511 +urn:mavedb:00000044-a-1#7240,NA,NA,p.Val181*,NA,NA,2,V511 +urn:mavedb:00000044-a-1#7241,NA,NA,p.Val182Ala,-0.65,-0.72,1,V512A +urn:mavedb:00000044-a-1#7242,NA,NA,p.Val182Ala,-0.79,-0.72,2,V512A +urn:mavedb:00000044-a-1#7243,NA,NA,p.Val182Cys,-0.65,-0.66,1,V512C +urn:mavedb:00000044-a-1#7244,NA,NA,p.Val182Cys,-0.67,-0.66,2,V512C +urn:mavedb:00000044-a-1#7245,NA,NA,p.Val182Asp,-1.72,-1.6,1,V512D +urn:mavedb:00000044-a-1#7246,NA,NA,p.Val182Asp,-1.47,-1.6,2,V512D +urn:mavedb:00000044-a-1#7247,NA,NA,p.Val182Glu,-4.24,-4.06,1,V512E +urn:mavedb:00000044-a-1#7248,NA,NA,p.Val182Glu,-3.87,-4.06,2,V512E +urn:mavedb:00000044-a-1#7249,NA,NA,p.Val182Phe,-4.74,-4.79,1,V512F +urn:mavedb:00000044-a-1#7250,NA,NA,p.Val182Phe,-4.84,-4.79,2,V512F +urn:mavedb:00000044-a-1#7251,NA,NA,p.Val182Gly,-4.76,-4.67,1,V512G +urn:mavedb:00000044-a-1#7252,NA,NA,p.Val182Gly,-4.58,-4.67,2,V512G +urn:mavedb:00000044-a-1#7253,NA,NA,p.Val182His,-4.33,-4.24,1,V512H +urn:mavedb:00000044-a-1#7254,NA,NA,p.Val182His,-4.16,-4.24,2,V512H +urn:mavedb:00000044-a-1#7255,NA,NA,p.Val182Ile,-0.22,-0.22,1,V512I +urn:mavedb:00000044-a-1#7256,NA,NA,p.Val182Ile,-0.22,-0.22,2,V512I +urn:mavedb:00000044-a-1#7257,NA,NA,p.Val182Lys,-3.82,-4.33,1,V512K +urn:mavedb:00000044-a-1#7258,NA,NA,p.Val182Lys,-4.84,-4.33,2,V512K +urn:mavedb:00000044-a-1#7259,NA,NA,p.Val182Leu,-4.3,-3.97,1,V512L +urn:mavedb:00000044-a-1#7260,NA,NA,p.Val182Leu,-3.64,-3.97,2,V512L +urn:mavedb:00000044-a-1#7261,NA,NA,p.Val182Met,-4.76,-4.34,1,V512M +urn:mavedb:00000044-a-1#7262,NA,NA,p.Val182Met,-3.92,-4.34,2,V512M +urn:mavedb:00000044-a-1#7263,NA,NA,p.Val182Asn,-4.76,-4.38,1,V512N +urn:mavedb:00000044-a-1#7264,NA,NA,p.Val182Asn,-4,-4.38,2,V512N +urn:mavedb:00000044-a-1#7265,NA,NA,p.Val182Pro,-3.35,-3.68,1,V512P +urn:mavedb:00000044-a-1#7266,NA,NA,p.Val182Pro,-4.02,-3.68,2,V512P +urn:mavedb:00000044-a-1#7267,NA,NA,p.Val182Gln,-4.45,-4.14,1,V512Q +urn:mavedb:00000044-a-1#7268,NA,NA,p.Val182Gln,-3.82,-4.14,2,V512Q +urn:mavedb:00000044-a-1#7269,NA,NA,p.Val182Arg,-4.76,-4.8,1,V512R +urn:mavedb:00000044-a-1#7270,NA,NA,p.Val182Arg,-4.84,-4.8,2,V512R +urn:mavedb:00000044-a-1#7271,NA,NA,p.Val182Ser,-1.12,-1.23,1,V512S +urn:mavedb:00000044-a-1#7272,NA,NA,p.Val182Ser,-1.33,-1.23,2,V512S +urn:mavedb:00000044-a-1#7273,NA,NA,p.Val182Thr,-0.72,-0.71,1,V512T +urn:mavedb:00000044-a-1#7274,NA,NA,p.Val182Thr,-0.7,-0.71,2,V512T +urn:mavedb:00000044-a-1#7275,NA,NA,p.Val182Trp,-3.77,-4.31,1,V512W +urn:mavedb:00000044-a-1#7276,NA,NA,p.Val182Trp,-4.84,-4.31,2,V512W +urn:mavedb:00000044-a-1#7277,NA,NA,p.Val182Tyr,-4.07,-4.15,1,V512Y +urn:mavedb:00000044-a-1#7278,NA,NA,p.Val182Tyr,-4.22,-4.15,2,V512Y +urn:mavedb:00000044-a-1#7279,NA,NA,p.Val182*,NA,NA,1,V512 +urn:mavedb:00000044-a-1#7280,NA,NA,p.Val182*,NA,NA,2,V512 +urn:mavedb:00000044-a-1#7281,NA,NA,p.Leu183Ala,-3.46,-3.14,1,L513A 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+urn:mavedb:00000044-a-1#7532,NA,NA,p.His189Gly,0.01,0,2,H519G +urn:mavedb:00000044-a-1#7533,NA,NA,p.His189Ile,-0.16,-0.13,1,H519I +urn:mavedb:00000044-a-1#7534,NA,NA,p.His189Ile,-0.1,-0.13,2,H519I +urn:mavedb:00000044-a-1#7535,NA,NA,p.His189Lys,0,-0.01,1,H519K +urn:mavedb:00000044-a-1#7536,NA,NA,p.His189Lys,-0.02,-0.01,2,H519K +urn:mavedb:00000044-a-1#7537,NA,NA,p.His189Leu,0.02,-0.06,1,H519L +urn:mavedb:00000044-a-1#7538,NA,NA,p.His189Leu,-0.14,-0.06,2,H519L +urn:mavedb:00000044-a-1#7539,NA,NA,p.His189Met,-1.11,-0.6,1,H519M +urn:mavedb:00000044-a-1#7540,NA,NA,p.His189Met,-0.08,-0.6,2,H519M +urn:mavedb:00000044-a-1#7541,NA,NA,p.His189Asn,0.04,0.05,1,H519N +urn:mavedb:00000044-a-1#7542,NA,NA,p.His189Asn,0.05,0.05,2,H519N +urn:mavedb:00000044-a-1#7543,NA,NA,p.His189Pro,0.04,0.02,1,H519P +urn:mavedb:00000044-a-1#7544,NA,NA,p.His189Pro,-0.01,0.02,2,H519P +urn:mavedb:00000044-a-1#7545,NA,NA,p.His189Gln,0,0,1,H519Q +urn:mavedb:00000044-a-1#7546,NA,NA,p.His189Gln,0,0,2,H519Q +urn:mavedb:00000044-a-1#7547,NA,NA,p.His189Arg,-0.06,-0.06,1,H519R +urn:mavedb:00000044-a-1#7548,NA,NA,p.His189Arg,-0.05,-0.06,2,H519R +urn:mavedb:00000044-a-1#7549,NA,NA,p.His189Ser,0.04,0.05,1,H519S +urn:mavedb:00000044-a-1#7550,NA,NA,p.His189Ser,0.06,0.05,2,H519S +urn:mavedb:00000044-a-1#7551,NA,NA,p.His189Thr,-0.02,0.02,1,H519T +urn:mavedb:00000044-a-1#7552,NA,NA,p.His189Thr,0.05,0.02,2,H519T +urn:mavedb:00000044-a-1#7553,NA,NA,p.His189Val,-0.02,0.01,1,H519V +urn:mavedb:00000044-a-1#7554,NA,NA,p.His189Val,0.04,0.01,2,H519V +urn:mavedb:00000044-a-1#7555,NA,NA,p.His189Trp,0.05,-0.07,1,H519W +urn:mavedb:00000044-a-1#7556,NA,NA,p.His189Trp,-0.18,-0.07,2,H519W +urn:mavedb:00000044-a-1#7557,NA,NA,p.His189Tyr,-0.04,-0.05,1,H519Y +urn:mavedb:00000044-a-1#7558,NA,NA,p.His189Tyr,-0.06,-0.05,2,H519Y +urn:mavedb:00000044-a-1#7559,NA,NA,p.His189*,NA,NA,1,H519 +urn:mavedb:00000044-a-1#7560,NA,NA,p.His189*,NA,NA,2,H519 +urn:mavedb:00000044-a-1#7561,NA,NA,p.Ala190Cys,-0.11,-0.2,1,A520C +urn:mavedb:00000044-a-1#7562,NA,NA,p.Ala190Cys,-0.28,-0.2,2,A520C +urn:mavedb:00000044-a-1#7563,NA,NA,p.Ala190Asp,0.03,-0.02,1,A520D +urn:mavedb:00000044-a-1#7564,NA,NA,p.Ala190Asp,-0.07,-0.02,2,A520D +urn:mavedb:00000044-a-1#7565,NA,NA,p.Ala190Glu,0.02,0.03,1,A520E +urn:mavedb:00000044-a-1#7566,NA,NA,p.Ala190Glu,0.04,0.03,2,A520E +urn:mavedb:00000044-a-1#7567,NA,NA,p.Ala190Phe,-0.04,-0.06,1,A520F +urn:mavedb:00000044-a-1#7568,NA,NA,p.Ala190Phe,-0.08,-0.06,2,A520F +urn:mavedb:00000044-a-1#7569,NA,NA,p.Ala190Gly,-0.03,0.05,1,A520G +urn:mavedb:00000044-a-1#7570,NA,NA,p.Ala190Gly,0.14,0.05,2,A520G +urn:mavedb:00000044-a-1#7571,NA,NA,p.Ala190His,0,0.01,1,A520H +urn:mavedb:00000044-a-1#7572,NA,NA,p.Ala190His,0.02,0.01,2,A520H +urn:mavedb:00000044-a-1#7573,NA,NA,p.Ala190Ile,-0.09,-0.16,1,A520I +urn:mavedb:00000044-a-1#7574,NA,NA,p.Ala190Ile,-0.24,-0.16,2,A520I +urn:mavedb:00000044-a-1#7575,NA,NA,p.Ala190Lys,0,-0.02,1,A520K +urn:mavedb:00000044-a-1#7576,NA,NA,p.Ala190Lys,-0.05,-0.02,2,A520K +urn:mavedb:00000044-a-1#7577,NA,NA,p.Ala190Leu,-0.06,-0.03,1,A520L +urn:mavedb:00000044-a-1#7578,NA,NA,p.Ala190Leu,-0.01,-0.03,2,A520L +urn:mavedb:00000044-a-1#7579,NA,NA,p.Ala190Met,-0.02,-0.05,1,A520M +urn:mavedb:00000044-a-1#7580,NA,NA,p.Ala190Met,-0.08,-0.05,2,A520M +urn:mavedb:00000044-a-1#7581,NA,NA,p.Ala190Asn,-0.06,-0.05,1,A520N +urn:mavedb:00000044-a-1#7582,NA,NA,p.Ala190Asn,-0.04,-0.05,2,A520N +urn:mavedb:00000044-a-1#7583,NA,NA,p.Ala190Pro,0,0.02,1,A520P +urn:mavedb:00000044-a-1#7584,NA,NA,p.Ala190Pro,0.03,0.02,2,A520P +urn:mavedb:00000044-a-1#7585,NA,NA,p.Ala190Gln,-0.05,-0.02,1,A520Q +urn:mavedb:00000044-a-1#7586,NA,NA,p.Ala190Gln,0.01,-0.02,2,A520Q +urn:mavedb:00000044-a-1#7587,NA,NA,p.Ala190Arg,-0.02,-0.03,1,A520R +urn:mavedb:00000044-a-1#7588,NA,NA,p.Ala190Arg,-0.05,-0.03,2,A520R +urn:mavedb:00000044-a-1#7589,NA,NA,p.Ala190Ser,-0.04,-0.04,1,A520S +urn:mavedb:00000044-a-1#7590,NA,NA,p.Ala190Ser,-0.04,-0.04,2,A520S +urn:mavedb:00000044-a-1#7591,NA,NA,p.Ala190Thr,-0.02,0,1,A520T +urn:mavedb:00000044-a-1#7592,NA,NA,p.Ala190Thr,0.02,0,2,A520T +urn:mavedb:00000044-a-1#7593,NA,NA,p.Ala190Val,-0.06,-0.08,1,A520V +urn:mavedb:00000044-a-1#7594,NA,NA,p.Ala190Val,-0.1,-0.08,2,A520V +urn:mavedb:00000044-a-1#7595,NA,NA,p.Ala190Trp,-0.29,-0.21,1,A520W +urn:mavedb:00000044-a-1#7596,NA,NA,p.Ala190Trp,-0.13,-0.21,2,A520W +urn:mavedb:00000044-a-1#7597,NA,NA,p.Ala190Tyr,-0.02,-0.02,1,A520Y +urn:mavedb:00000044-a-1#7598,NA,NA,p.Ala190Tyr,-0.01,-0.02,2,A520Y +urn:mavedb:00000044-a-1#7599,NA,NA,p.Ala190*,NA,NA,1,A520 +urn:mavedb:00000044-a-1#7600,NA,NA,p.Ala190*,NA,NA,2,A520 +urn:mavedb:00000044-a-1#7601,NA,NA,p.Pro191Ala,-0.04,-0.04,1,P521A +urn:mavedb:00000044-a-1#7602,NA,NA,p.Pro191Ala,NA,-0.04,2,P521A +urn:mavedb:00000044-a-1#7603,NA,NA,p.Pro191Cys,-0.04,-0.11,1,P521C +urn:mavedb:00000044-a-1#7604,NA,NA,p.Pro191Cys,-0.18,-0.11,2,P521C +urn:mavedb:00000044-a-1#7605,NA,NA,p.Pro191Asp,0,0,1,P521D +urn:mavedb:00000044-a-1#7606,NA,NA,p.Pro191Asp,0,0,2,P521D +urn:mavedb:00000044-a-1#7607,NA,NA,p.Pro191Glu,0,0,1,P521E +urn:mavedb:00000044-a-1#7608,NA,NA,p.Pro191Glu,0,0,2,P521E +urn:mavedb:00000044-a-1#7609,NA,NA,p.Pro191Phe,-0.15,-0.15,1,P521F +urn:mavedb:00000044-a-1#7684,NA,NA,p.Thr193Cys,NA,NA,2,T523C +urn:mavedb:00000044-a-1#7724,NA,NA,p.Val194Cys,NA,NA,2,V524C +urn:mavedb:00000044-a-1#7610,NA,NA,p.Pro191Phe,-0.15,-0.15,2,P521F +urn:mavedb:00000044-a-1#7611,NA,NA,p.Pro191Gly,0.04,0.02,1,P521G +urn:mavedb:00000044-a-1#7612,NA,NA,p.Pro191Gly,0.01,0.02,2,P521G +urn:mavedb:00000044-a-1#7613,NA,NA,p.Pro191His,-0.04,0,1,P521H +urn:mavedb:00000044-a-1#7614,NA,NA,p.Pro191His,0.03,0,2,P521H +urn:mavedb:00000044-a-1#7615,NA,NA,p.Pro191Ile,-0.16,-0.2,1,P521I +urn:mavedb:00000044-a-1#7616,NA,NA,p.Pro191Ile,-0.24,-0.2,2,P521I +urn:mavedb:00000044-a-1#7617,NA,NA,p.Pro191Lys,-0.06,-0.08,1,P521K +urn:mavedb:00000044-a-1#7618,NA,NA,p.Pro191Lys,-0.09,-0.08,2,P521K +urn:mavedb:00000044-a-1#7619,NA,NA,p.Pro191Leu,-0.12,-0.2,1,P521L +urn:mavedb:00000044-a-1#7620,NA,NA,p.Pro191Leu,-0.27,-0.2,2,P521L +urn:mavedb:00000044-a-1#7621,NA,NA,p.Pro191Met,-0.07,-0.08,1,P521M +urn:mavedb:00000044-a-1#7622,NA,NA,p.Pro191Met,-0.09,-0.08,2,P521M +urn:mavedb:00000044-a-1#7623,NA,NA,p.Pro191Asn,0,-0.06,1,P521N +urn:mavedb:00000044-a-1#7624,NA,NA,p.Pro191Asn,-0.12,-0.06,2,P521N +urn:mavedb:00000044-a-1#7625,NA,NA,p.Pro191Gln,NA,0,1,P521Q +urn:mavedb:00000044-a-1#7626,NA,NA,p.Pro191Gln,0,0,2,P521Q +urn:mavedb:00000044-a-1#7627,NA,NA,p.Pro191Arg,0.02,-0.01,1,P521R +urn:mavedb:00000044-a-1#7628,NA,NA,p.Pro191Arg,-0.04,-0.01,2,P521R +urn:mavedb:00000044-a-1#7629,NA,NA,p.Pro191Ser,-0.02,0.04,1,P521S +urn:mavedb:00000044-a-1#7630,NA,NA,p.Pro191Ser,0.1,0.04,2,P521S +urn:mavedb:00000044-a-1#7631,NA,NA,p.Pro191Thr,-0.04,-0.03,1,P521T +urn:mavedb:00000044-a-1#7632,NA,NA,p.Pro191Thr,-0.02,-0.03,2,P521T +urn:mavedb:00000044-a-1#7633,NA,NA,p.Pro191Val,0,-0.06,1,P521V +urn:mavedb:00000044-a-1#7634,NA,NA,p.Pro191Val,-0.12,-0.06,2,P521V +urn:mavedb:00000044-a-1#7635,NA,NA,p.Pro191Trp,-0.26,-0.57,1,P521W +urn:mavedb:00000044-a-1#7636,NA,NA,p.Pro191Trp,-0.89,-0.57,2,P521W +urn:mavedb:00000044-a-1#7637,NA,NA,p.Pro191Tyr,-0.13,-0.12,1,P521Y +urn:mavedb:00000044-a-1#7638,NA,NA,p.Pro191Tyr,-0.12,-0.12,2,P521Y +urn:mavedb:00000044-a-1#7639,NA,NA,p.Pro191*,NA,NA,1,P521 +urn:mavedb:00000044-a-1#7640,NA,NA,p.Pro191*,NA,NA,2,P521 +urn:mavedb:00000044-a-1#7641,NA,NA,p.Ala192Cys,-0.07,-0.07,1,A522C +urn:mavedb:00000044-a-1#7642,NA,NA,p.Ala192Cys,-0.06,-0.07,2,A522C +urn:mavedb:00000044-a-1#7643,NA,NA,p.Ala192Asp,-0.06,-0.04,1,A522D +urn:mavedb:00000044-a-1#7644,NA,NA,p.Ala192Asp,-0.03,-0.04,2,A522D +urn:mavedb:00000044-a-1#7645,NA,NA,p.Ala192Glu,0,-0.01,1,A522E +urn:mavedb:00000044-a-1#7646,NA,NA,p.Ala192Glu,-0.02,-0.01,2,A522E +urn:mavedb:00000044-a-1#7647,NA,NA,p.Ala192Phe,0,0,1,A522F +urn:mavedb:00000044-a-1#7648,NA,NA,p.Ala192Phe,0,0,2,A522F +urn:mavedb:00000044-a-1#7649,NA,NA,p.Ala192Gly,0,0,1,A522G +urn:mavedb:00000044-a-1#7650,NA,NA,p.Ala192Gly,0,0,2,A522G +urn:mavedb:00000044-a-1#7651,NA,NA,p.Ala192His,0.05,0.03,1,A522H +urn:mavedb:00000044-a-1#7652,NA,NA,p.Ala192His,0.02,0.03,2,A522H +urn:mavedb:00000044-a-1#7653,NA,NA,p.Ala192Ile,-0.02,-0.01,1,A522I +urn:mavedb:00000044-a-1#7654,NA,NA,p.Ala192Ile,0,-0.01,2,A522I +urn:mavedb:00000044-a-1#7655,NA,NA,p.Ala192Lys,-0.01,0.01,1,A522K +urn:mavedb:00000044-a-1#7656,NA,NA,p.Ala192Lys,0.03,0.01,2,A522K +urn:mavedb:00000044-a-1#7657,NA,NA,p.Ala192Leu,0,-0.05,1,A522L +urn:mavedb:00000044-a-1#7658,NA,NA,p.Ala192Leu,-0.11,-0.05,2,A522L +urn:mavedb:00000044-a-1#7659,NA,NA,p.Ala192Met,-0.03,0.01,1,A522M +urn:mavedb:00000044-a-1#7660,NA,NA,p.Ala192Met,0.05,0.01,2,A522M +urn:mavedb:00000044-a-1#7661,NA,NA,p.Ala192Asn,0,0,1,A522N +urn:mavedb:00000044-a-1#7662,NA,NA,p.Ala192Asn,0,0,2,A522N +urn:mavedb:00000044-a-1#7663,NA,NA,p.Ala192Pro,0.09,0.04,1,A522P +urn:mavedb:00000044-a-1#7664,NA,NA,p.Ala192Pro,-0.01,0.04,2,A522P +urn:mavedb:00000044-a-1#7665,NA,NA,p.Ala192Gln,-0.07,-0.04,1,A522Q +urn:mavedb:00000044-a-1#7666,NA,NA,p.Ala192Gln,-0.02,-0.04,2,A522Q +urn:mavedb:00000044-a-1#7667,NA,NA,p.Ala192Arg,0,-0.02,1,A522R +urn:mavedb:00000044-a-1#7668,NA,NA,p.Ala192Arg,-0.05,-0.02,2,A522R +urn:mavedb:00000044-a-1#7669,NA,NA,p.Ala192Ser,-0.02,-0.03,1,A522S +urn:mavedb:00000044-a-1#7670,NA,NA,p.Ala192Ser,-0.04,-0.03,2,A522S +urn:mavedb:00000044-a-1#7671,NA,NA,p.Ala192Thr,0.05,0.02,1,A522T +urn:mavedb:00000044-a-1#7672,NA,NA,p.Ala192Thr,-0.01,0.02,2,A522T +urn:mavedb:00000044-a-1#7673,NA,NA,p.Ala192Val,0.03,-0.03,1,A522V +urn:mavedb:00000044-a-1#7674,NA,NA,p.Ala192Val,-0.09,-0.03,2,A522V +urn:mavedb:00000044-a-1#7675,NA,NA,p.Ala192Trp,0,-0.02,1,A522W +urn:mavedb:00000044-a-1#7676,NA,NA,p.Ala192Trp,-0.03,-0.02,2,A522W +urn:mavedb:00000044-a-1#7677,NA,NA,p.Ala192Tyr,0,0,1,A522Y +urn:mavedb:00000044-a-1#7678,NA,NA,p.Ala192Tyr,0.01,0,2,A522Y +urn:mavedb:00000044-a-1#7679,NA,NA,p.Ala192*,NA,NA,1,A522 +urn:mavedb:00000044-a-1#7680,NA,NA,p.Ala192*,NA,NA,2,A522 +urn:mavedb:00000044-a-1#7681,NA,NA,p.Thr193Ala,-0.01,-0.03,1,T523A +urn:mavedb:00000044-a-1#7682,NA,NA,p.Thr193Ala,-0.05,-0.03,2,T523A +urn:mavedb:00000044-a-1#7683,NA,NA,p.Thr193Cys,NA,NA,1,T523C +urn:mavedb:00000044-a-1#7685,NA,NA,p.Thr193Asp,0,-0.23,1,T523D +urn:mavedb:00000044-a-1#7686,NA,NA,p.Thr193Asp,-0.47,-0.23,2,T523D +urn:mavedb:00000044-a-1#7687,NA,NA,p.Thr193Glu,NA,NA,1,T523E +urn:mavedb:00000044-a-1#7688,NA,NA,p.Thr193Glu,NA,NA,2,T523E +urn:mavedb:00000044-a-1#7689,NA,NA,p.Thr193Phe,NA,0.01,1,T523F +urn:mavedb:00000044-a-1#7690,NA,NA,p.Thr193Phe,0.01,0.01,2,T523F +urn:mavedb:00000044-a-1#7691,NA,NA,p.Thr193Gly,-0.01,-0.01,1,T523G +urn:mavedb:00000044-a-1#7692,NA,NA,p.Thr193Gly,-0.02,-0.01,2,T523G +urn:mavedb:00000044-a-1#7693,NA,NA,p.Thr193His,0,0,1,T523H +urn:mavedb:00000044-a-1#7694,NA,NA,p.Thr193His,NA,0,2,T523H +urn:mavedb:00000044-a-1#7695,NA,NA,p.Thr193Ile,-0.09,-0.09,1,T523I +urn:mavedb:00000044-a-1#7696,NA,NA,p.Thr193Ile,-0.08,-0.09,2,T523I +urn:mavedb:00000044-a-1#7697,NA,NA,p.Thr193Lys,-0.02,-0.02,1,T523K +urn:mavedb:00000044-a-1#7698,NA,NA,p.Thr193Lys,NA,-0.02,2,T523K +urn:mavedb:00000044-a-1#7699,NA,NA,p.Thr193Leu,NA,-0.1,1,T523L +urn:mavedb:00000044-a-1#7700,NA,NA,p.Thr193Leu,-0.1,-0.1,2,T523L +urn:mavedb:00000044-a-1#7701,NA,NA,p.Thr193Met,NA,NA,1,T523M +urn:mavedb:00000044-a-1#7702,NA,NA,p.Thr193Met,NA,NA,2,T523M +urn:mavedb:00000044-a-1#7703,NA,NA,p.Thr193Asn,0,-0.02,1,T523N +urn:mavedb:00000044-a-1#7704,NA,NA,p.Thr193Asn,-0.03,-0.02,2,T523N +urn:mavedb:00000044-a-1#7705,NA,NA,p.Thr193Pro,-0.01,-0.01,1,T523P +urn:mavedb:00000044-a-1#7706,NA,NA,p.Thr193Pro,NA,-0.01,2,T523P +urn:mavedb:00000044-a-1#7707,NA,NA,p.Thr193Gln,0,0,1,T523Q +urn:mavedb:00000044-a-1#7708,NA,NA,p.Thr193Gln,NA,0,2,T523Q +urn:mavedb:00000044-a-1#7709,NA,NA,p.Thr193Arg,0,0,1,T523R +urn:mavedb:00000044-a-1#7710,NA,NA,p.Thr193Arg,-0.01,0,2,T523R +urn:mavedb:00000044-a-1#7711,NA,NA,p.Thr193Ser,0,-0.02,1,T523S +urn:mavedb:00000044-a-1#7712,NA,NA,p.Thr193Ser,-0.04,-0.02,2,T523S +urn:mavedb:00000044-a-1#7713,NA,NA,p.Thr193Val,NA,0,1,T523V +urn:mavedb:00000044-a-1#7714,NA,NA,p.Thr193Val,0,0,2,T523V +urn:mavedb:00000044-a-1#7715,NA,NA,p.Thr193Trp,NA,NA,1,T523W +urn:mavedb:00000044-a-1#7716,NA,NA,p.Thr193Trp,NA,NA,2,T523W +urn:mavedb:00000044-a-1#7717,NA,NA,p.Thr193Tyr,-0.01,-0.01,1,T523Y +urn:mavedb:00000044-a-1#7718,NA,NA,p.Thr193Tyr,-0.01,-0.01,2,T523Y +urn:mavedb:00000044-a-1#7719,NA,NA,p.Thr193*,NA,NA,1,T523 +urn:mavedb:00000044-a-1#7720,NA,NA,p.Thr193*,NA,NA,2,T523 +urn:mavedb:00000044-a-1#7721,NA,NA,p.Val194Ala,-0.06,-0.07,1,V524A +urn:mavedb:00000044-a-1#7722,NA,NA,p.Val194Ala,-0.08,-0.07,2,V524A +urn:mavedb:00000044-a-1#7723,NA,NA,p.Val194Cys,NA,NA,1,V524C +urn:mavedb:00000044-a-1#7725,NA,NA,p.Val194Asp,NA,-0.53,1,V524D +urn:mavedb:00000044-a-1#7726,NA,NA,p.Val194Asp,-0.53,-0.53,2,V524D +urn:mavedb:00000044-a-1#7727,NA,NA,p.Val194Glu,NA,-0.1,1,V524E +urn:mavedb:00000044-a-1#7728,NA,NA,p.Val194Glu,-0.1,-0.1,2,V524E +urn:mavedb:00000044-a-1#7729,NA,NA,p.Val194Phe,NA,NA,1,V524F +urn:mavedb:00000044-a-1#7730,NA,NA,p.Val194Phe,NA,NA,2,V524F +urn:mavedb:00000044-a-1#7731,NA,NA,p.Val194Gly,-0.01,-0.02,1,V524G +urn:mavedb:00000044-a-1#7732,NA,NA,p.Val194Gly,-0.03,-0.02,2,V524G +urn:mavedb:00000044-a-1#7733,NA,NA,p.Val194His,NA,NA,1,V524H +urn:mavedb:00000044-a-1#7734,NA,NA,p.Val194His,NA,NA,2,V524H +urn:mavedb:00000044-a-1#7735,NA,NA,p.Val194Ile,-0.06,-0.06,1,V524I +urn:mavedb:00000044-a-1#7736,NA,NA,p.Val194Ile,-0.05,-0.06,2,V524I +urn:mavedb:00000044-a-1#7737,NA,NA,p.Val194Lys,NA,NA,1,V524K +urn:mavedb:00000044-a-1#7738,NA,NA,p.Val194Lys,NA,NA,2,V524K +urn:mavedb:00000044-a-1#7739,NA,NA,p.Val194Leu,-0.01,-0.01,1,V524L +urn:mavedb:00000044-a-1#7740,NA,NA,p.Val194Leu,-0.02,-0.01,2,V524L +urn:mavedb:00000044-a-1#7741,NA,NA,p.Val194Met,NA,NA,1,V524M +urn:mavedb:00000044-a-1#7742,NA,NA,p.Val194Met,NA,NA,2,V524M +urn:mavedb:00000044-a-1#7743,NA,NA,p.Val194Asn,NA,NA,1,V524N +urn:mavedb:00000044-a-1#7744,NA,NA,p.Val194Asn,NA,NA,2,V524N +urn:mavedb:00000044-a-1#7745,NA,NA,p.Val194Pro,-2.62,-1.31,1,V524P +urn:mavedb:00000044-a-1#7746,NA,NA,p.Val194Pro,0.01,-1.31,2,V524P +urn:mavedb:00000044-a-1#7747,NA,NA,p.Val194Gln,NA,NA,1,V524Q +urn:mavedb:00000044-a-1#7748,NA,NA,p.Val194Gln,NA,NA,2,V524Q +urn:mavedb:00000044-a-1#7749,NA,NA,p.Val194Arg,-0.63,-0.34,1,V524R +urn:mavedb:00000044-a-1#7750,NA,NA,p.Val194Arg,-0.04,-0.34,2,V524R +urn:mavedb:00000044-a-1#7430,NA,NA,p.Glu186Ser,-0.12,-0.13,2,E516S +urn:mavedb:00000044-a-1#7431,NA,NA,p.Glu186Thr,-0.07,-0.13,1,E516T +urn:mavedb:00000044-a-1#7432,NA,NA,p.Glu186Thr,-0.18,-0.13,2,E516T +urn:mavedb:00000044-a-1#7433,NA,NA,p.Glu186Val,-0.28,-0.28,1,E516V +urn:mavedb:00000044-a-1#7434,NA,NA,p.Glu186Val,-0.28,-0.28,2,E516V +urn:mavedb:00000044-a-1#7435,NA,NA,p.Glu186Trp,-0.04,-0.08,1,E516W +urn:mavedb:00000044-a-1#7436,NA,NA,p.Glu186Trp,-0.12,-0.08,2,E516W +urn:mavedb:00000044-a-1#7437,NA,NA,p.Glu186Tyr,-0.31,-0.3,1,E516Y +urn:mavedb:00000044-a-1#7438,NA,NA,p.Glu186Tyr,-0.29,-0.3,2,E516Y +urn:mavedb:00000044-a-1#7439,NA,NA,p.Glu186*,NA,NA,1,E516 +urn:mavedb:00000044-a-1#7440,NA,NA,p.Glu186*,NA,NA,2,E516 +urn:mavedb:00000044-a-1#7441,NA,NA,p.Leu187Ala,-0.15,-0.08,1,L517A +urn:mavedb:00000044-a-1#7442,NA,NA,p.Leu187Ala,-0.01,-0.08,2,L517A +urn:mavedb:00000044-a-1#7443,NA,NA,p.Leu187Cys,-0.03,-0.03,1,L517C +urn:mavedb:00000044-a-1#7444,NA,NA,p.Leu187Cys,-0.04,-0.03,2,L517C +urn:mavedb:00000044-a-1#7445,NA,NA,p.Leu187Asp,-0.01,-0.02,1,L517D +urn:mavedb:00000044-a-1#7446,NA,NA,p.Leu187Asp,-0.02,-0.02,2,L517D +urn:mavedb:00000044-a-1#7447,NA,NA,p.Leu187Glu,-0.11,-0.07,1,L517E +urn:mavedb:00000044-a-1#7448,NA,NA,p.Leu187Glu,-0.03,-0.07,2,L517E +urn:mavedb:00000044-a-1#7449,NA,NA,p.Leu187Phe,-0.01,-0.02,1,L517F +urn:mavedb:00000044-a-1#7450,NA,NA,p.Leu187Phe,-0.03,-0.02,2,L517F +urn:mavedb:00000044-a-1#7451,NA,NA,p.Leu187Gly,-0.03,-0.01,1,L517G +urn:mavedb:00000044-a-1#7452,NA,NA,p.Leu187Gly,0.01,-0.01,2,L517G +urn:mavedb:00000044-a-1#7453,NA,NA,p.Leu187His,-0.01,-0.05,1,L517H +urn:mavedb:00000044-a-1#7454,NA,NA,p.Leu187His,-0.09,-0.05,2,L517H +urn:mavedb:00000044-a-1#7455,NA,NA,p.Leu187Ile,-0.11,-0.07,1,L517I +urn:mavedb:00000044-a-1#7456,NA,NA,p.Leu187Ile,-0.04,-0.07,2,L517I +urn:mavedb:00000044-a-1#7457,NA,NA,p.Leu187Lys,0.01,0.04,1,L517K +urn:mavedb:00000044-a-1#7458,NA,NA,p.Leu187Lys,0.08,0.04,2,L517K +urn:mavedb:00000044-a-1#7459,NA,NA,p.Leu187Met,0.25,0.13,1,L517M +urn:mavedb:00000044-a-1#7460,NA,NA,p.Leu187Met,0,0.13,2,L517M +urn:mavedb:00000044-a-1#7461,NA,NA,p.Leu187Asn,0,-0.04,1,L517N +urn:mavedb:00000044-a-1#7751,NA,NA,p.Val194Ser,NA,NA,1,V524S +urn:mavedb:00000044-a-1#7752,NA,NA,p.Val194Ser,NA,NA,2,V524S +urn:mavedb:00000044-a-1#7753,NA,NA,p.Val194Thr,-0.69,-0.69,1,V524T +urn:mavedb:00000044-a-1#7754,NA,NA,p.Val194Thr,NA,-0.69,2,V524T +urn:mavedb:00000044-a-1#7755,NA,NA,p.Val194Trp,-1.08,-1.08,1,V524W +urn:mavedb:00000044-a-1#7756,NA,NA,p.Val194Trp,NA,-1.08,2,V524W +urn:mavedb:00000044-a-1#7757,NA,NA,p.Val194Tyr,NA,-0.18,1,V524Y +urn:mavedb:00000044-a-1#7758,NA,NA,p.Val194Tyr,-0.18,-0.18,2,V524Y +urn:mavedb:00000044-a-1#7759,NA,NA,p.Val194*,NA,NA,1,V524 +urn:mavedb:00000044-a-1#7760,NA,NA,p.Val194*,NA,NA,2,V524 +urn:mavedb:00000044-a-1#7761,NA,NA,p.Cys195Ala,-0.11,-0.07,1,C525A +urn:mavedb:00000044-a-1#7762,NA,NA,p.Cys195Ala,-0.04,-0.07,2,C525A +urn:mavedb:00000044-a-1#7763,NA,NA,p.Cys195Asp,-0.05,-0.05,1,C525D +urn:mavedb:00000044-a-1#7768,NA,NA,p.Cys195Phe,-0.09,-0.02,2,C525F +urn:mavedb:00000044-a-1#7764,NA,NA,p.Cys195Asp,-0.06,-0.05,2,C525D +urn:mavedb:00000044-a-1#7765,NA,NA,p.Cys195Glu,0,-0.02,1,C525E +urn:mavedb:00000044-a-1#7766,NA,NA,p.Cys195Glu,-0.04,-0.02,2,C525E +urn:mavedb:00000044-a-1#7767,NA,NA,p.Cys195Phe,0.06,-0.02,1,C525F +urn:mavedb:00000044-a-1#7769,NA,NA,p.Cys195Gly,-0.46,-0.25,1,C525G +urn:mavedb:00000044-a-1#7770,NA,NA,p.Cys195Gly,-0.03,-0.25,2,C525G +urn:mavedb:00000044-a-1#7771,NA,NA,p.Cys195His,-0.3,-0.49,1,C525H +urn:mavedb:00000044-a-1#7772,NA,NA,p.Cys195His,-0.67,-0.49,2,C525H +urn:mavedb:00000044-a-1#7773,NA,NA,p.Cys195Ile,-0.05,-0.05,1,C525I +urn:mavedb:00000044-a-1#7774,NA,NA,p.Cys195Ile,-0.05,-0.05,2,C525I +urn:mavedb:00000044-a-1#7775,NA,NA,p.Cys195Lys,-0.08,-0.07,1,C525K +urn:mavedb:00000044-a-1#7776,NA,NA,p.Cys195Lys,-0.05,-0.07,2,C525K +urn:mavedb:00000044-a-1#7777,NA,NA,p.Cys195Leu,-0.06,-0.07,1,C525L +urn:mavedb:00000044-a-1#7778,NA,NA,p.Cys195Leu,-0.08,-0.07,2,C525L +urn:mavedb:00000044-a-1#7779,NA,NA,p.Cys195Met,-0.06,-0.03,1,C525M +urn:mavedb:00000044-a-1#7780,NA,NA,p.Cys195Met,0.01,-0.03,2,C525M +urn:mavedb:00000044-a-1#7781,NA,NA,p.Cys195Asn,-0.02,-0.02,1,C525N +urn:mavedb:00000044-a-1#7782,NA,NA,p.Cys195Asn,-0.02,-0.02,2,C525N +urn:mavedb:00000044-a-1#7783,NA,NA,p.Cys195Pro,-1.54,-0.84,1,C525P +urn:mavedb:00000044-a-1#7784,NA,NA,p.Cys195Pro,-0.15,-0.84,2,C525P +urn:mavedb:00000044-a-1#7785,NA,NA,p.Cys195Gln,-0.7,-0.35,1,C525Q +urn:mavedb:00000044-a-1#7786,NA,NA,p.Cys195Gln,0.01,-0.35,2,C525Q +urn:mavedb:00000044-a-1#7787,NA,NA,p.Cys195Arg,-0.05,-0.08,1,C525R +urn:mavedb:00000044-a-1#7788,NA,NA,p.Cys195Arg,-0.12,-0.08,2,C525R +urn:mavedb:00000044-a-1#7789,NA,NA,p.Cys195Ser,-0.04,-0.04,1,C525S +urn:mavedb:00000044-a-1#7790,NA,NA,p.Cys195Ser,-0.05,-0.04,2,C525S +urn:mavedb:00000044-a-1#7791,NA,NA,p.Cys195Thr,-0.08,-0.08,1,C525T +urn:mavedb:00000044-a-1#7792,NA,NA,p.Cys195Thr,-0.08,-0.08,2,C525T +urn:mavedb:00000044-a-1#7793,NA,NA,p.Cys195Val,-0.05,-0.06,1,C525V +urn:mavedb:00000044-a-1#7794,NA,NA,p.Cys195Val,-0.07,-0.06,2,C525V +urn:mavedb:00000044-a-1#7795,NA,NA,p.Cys195Trp,-0.05,-0.11,1,C525W +urn:mavedb:00000044-a-1#7796,NA,NA,p.Cys195Trp,-0.16,-0.11,2,C525W 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+urn:mavedb:00000044-a-1#7483,NA,NA,p.Leu188Cys,0,0,1,L518C +urn:mavedb:00000044-a-1#7484,NA,NA,p.Leu188Cys,0.01,0,2,L518C +urn:mavedb:00000044-a-1#7485,NA,NA,p.Leu188Asp,0,0.04,1,L518D +urn:mavedb:00000044-a-1#7486,NA,NA,p.Leu188Asp,0.07,0.04,2,L518D +urn:mavedb:00000044-a-1#7487,NA,NA,p.Leu188Glu,0,0,1,L518E +urn:mavedb:00000044-a-1#7488,NA,NA,p.Leu188Glu,0.01,0,2,L518E +urn:mavedb:00000044-a-1#7489,NA,NA,p.Leu188Phe,-0.06,-0.06,1,L518F +urn:mavedb:00000044-a-1#7490,NA,NA,p.Leu188Phe,-0.06,-0.06,2,L518F +urn:mavedb:00000044-a-1#7491,NA,NA,p.Leu188Gly,0,0,1,L518G +urn:mavedb:00000044-a-1#7492,NA,NA,p.Leu188Gly,0.01,0,2,L518G +urn:mavedb:00000044-a-1#7493,NA,NA,p.Leu188His,0.02,-0.03,1,L518H +urn:mavedb:00000044-a-1#7494,NA,NA,p.Leu188His,-0.09,-0.03,2,L518H +urn:mavedb:00000044-a-1#7495,NA,NA,p.Leu188Ile,0.04,0,1,L518I +urn:mavedb:00000044-a-1#4296,NA,NA,p.Ser108Ile,-2.43,-2.39,2,S438I +urn:mavedb:00000044-a-1#4297,NA,NA,p.Ser108Lys,-2.56,-2.39,1,S438K +urn:mavedb:00000044-a-1#4298,NA,NA,p.Ser108Lys,-2.22,-2.39,2,S438K +urn:mavedb:00000044-a-1#4299,NA,NA,p.Ser108Leu,-3.51,-3.43,1,S438L +urn:mavedb:00000044-a-1#4300,NA,NA,p.Ser108Leu,-3.34,-3.43,2,S438L +urn:mavedb:00000044-a-1#4301,NA,NA,p.Ser108Met,-1.45,-1.42,1,S438M +urn:mavedb:00000044-a-1#4302,NA,NA,p.Ser108Met,-1.38,-1.42,2,S438M +urn:mavedb:00000044-a-1#4303,NA,NA,p.Ser108Asn,-0.88,-1.41,1,S438N +urn:mavedb:00000044-a-1#4304,NA,NA,p.Ser108Asn,-1.93,-1.41,2,S438N +urn:mavedb:00000044-a-1#4305,NA,NA,p.Ser108Pro,-4.76,-4.61,1,S438P +urn:mavedb:00000044-a-1#4307,NA,NA,p.Ser108Gln,-1.15,-1.39,1,S438Q +urn:mavedb:00000044-a-1#4308,NA,NA,p.Ser108Gln,-1.62,-1.39,2,S438Q +urn:mavedb:00000044-a-1#4309,NA,NA,p.Ser108Arg,-0.93,-1.27,1,S438R +urn:mavedb:00000044-a-1#4310,NA,NA,p.Ser108Arg,-1.6,-1.27,2,S438R +urn:mavedb:00000044-a-1#6712,NA,NA,p.Gln168Thr,-0.66,-0.67,2,Q498T +urn:mavedb:00000044-a-1#4319,NA,NA,p.Ser108*,NA,NA,1,S438 +urn:mavedb:00000044-a-1#4320,NA,NA,p.Ser108*,NA,NA,2,S438 +urn:mavedb:00000044-a-1#4315,NA,NA,p.Ser108Trp,-3.21,-2.99,1,S438W +urn:mavedb:00000044-a-1#4316,NA,NA,p.Ser108Trp,-2.76,-2.99,2,S438W +urn:mavedb:00000044-a-1#4317,NA,NA,p.Ser108Tyr,-2.49,-2.56,1,S438Y +urn:mavedb:00000044-a-1#4318,NA,NA,p.Ser108Tyr,-2.62,-2.56,2,S438Y +urn:mavedb:00000044-a-1#4324,NA,NA,p.Asn109Cys,-0.1,-0.12,2,N439C +urn:mavedb:00000044-a-1#4325,NA,NA,p.Asn109Asp,-1.01,-1.15,1,N439D +urn:mavedb:00000044-a-1#4331,NA,NA,p.Asn109Gly,-0.37,-0.5,1,N439G +urn:mavedb:00000044-a-1#4332,NA,NA,p.Asn109Gly,-0.64,-0.5,2,N439G +urn:mavedb:00000044-a-1#4333,NA,NA,p.Asn109His,-0.62,-0.75,1,N439H +urn:mavedb:00000044-a-1#4334,NA,NA,p.Asn109His,-0.87,-0.75,2,N439H +urn:mavedb:00000044-a-1#4335,NA,NA,p.Asn109Ile,-0.28,-0.25,1,N439I +urn:mavedb:00000044-a-1#4336,NA,NA,p.Asn109Ile,-0.21,-0.25,2,N439I +urn:mavedb:00000044-a-1#4340,NA,NA,p.Asn109Leu,-0.08,-0.06,2,N439L +urn:mavedb:00000044-a-1#4341,NA,NA,p.Asn109Met,-0.24,-0.25,1,N439M +urn:mavedb:00000044-a-1#4342,NA,NA,p.Asn109Met,-0.26,-0.25,2,N439M +urn:mavedb:00000044-a-1#4361,NA,NA,p.Asn110Ala,0.03,0.01,1,N440A +urn:mavedb:00000044-a-1#4347,NA,NA,p.Asn109Arg,-0.11,-0.03,1,N439R +urn:mavedb:00000044-a-1#4348,NA,NA,p.Asn109Arg,0.05,-0.03,2,N439R +urn:mavedb:00000044-a-1#4349,NA,NA,p.Asn109Ser,-1.04,-1.22,1,N439S +urn:mavedb:00000044-a-1#4355,NA,NA,p.Asn109Trp,-0.33,-0.58,1,N439W +urn:mavedb:00000044-a-1#4356,NA,NA,p.Asn109Trp,-0.82,-0.58,2,N439W +urn:mavedb:00000044-a-1#4363,NA,NA,p.Asn110Cys,-0.16,-0.15,1,N440C +urn:mavedb:00000044-a-1#4364,NA,NA,p.Asn110Cys,-0.15,-0.15,2,N440C +urn:mavedb:00000044-a-1#4365,NA,NA,p.Asn110Asp,-0.03,-0.02,1,N440D +urn:mavedb:00000044-a-1#4366,NA,NA,p.Asn110Asp,-0.02,-0.02,2,N440D +urn:mavedb:00000044-a-1#4367,NA,NA,p.Asn110Glu,0,-0.04,1,N440E +urn:mavedb:00000044-a-1#4368,NA,NA,p.Asn110Glu,-0.08,-0.04,2,N440E +urn:mavedb:00000044-a-1#4371,NA,NA,p.Asn110Gly,0.02,-0.01,1,N440G \ No newline at end of file diff --git a/example_data/example_mave_data/input/MaveExpRBD.csv b/example_data/example_mave_data/input/MaveExpRBD.csv new file mode 100644 index 0000000..75ba9aa --- /dev/null +++ b/example_data/example_mave_data/input/MaveExpRBD.csv @@ -0,0 +1,8041 @@ +accession,hgvs_nt,hgvs_splice,hgvs_pro,score,average,library,AA +urn:mavedb:00000044-b-2#4199,NA,NA,p.Ala105*,-4.58,-4.57,1,A435 +urn:mavedb:00000044-b-2#4200,NA,NA,p.Ala105*,-4.55,-4.57,2,A435 +urn:mavedb:00000044-b-2#4187,NA,NA,p.Ala105Arg,-2.86,-2.82,1,A435R +urn:mavedb:00000044-b-2#4188,NA,NA,p.Ala105Arg,-2.78,-2.82,2,A435R +urn:mavedb:00000044-b-2#4181,NA,NA,p.Ala105Asn,-2.92,-2.84,1,A435N +urn:mavedb:00000044-b-2#4182,NA,NA,p.Ala105Asn,-2.77,-2.84,2,A435N +urn:mavedb:00000044-b-2#4163,NA,NA,p.Ala105Asp,-3,-2.91,1,A435D +urn:mavedb:00000044-b-2#4164,NA,NA,p.Ala105Asp,-2.81,-2.91,2,A435D +urn:mavedb:00000044-b-2#4161,NA,NA,p.Ala105Cys,-1.72,-1.74,1,A435C +urn:mavedb:00000044-b-2#4162,NA,NA,p.Ala105Cys,-1.76,-1.74,2,A435C +urn:mavedb:00000044-b-2#4185,NA,NA,p.Ala105Gln,-2.6,-2.57,1,A435Q +urn:mavedb:00000044-b-2#4186,NA,NA,p.Ala105Gln,-2.53,-2.57,2,A435Q +urn:mavedb:00000044-b-2#4165,NA,NA,p.Ala105Glu,-2.87,-2.81,1,A435E +urn:mavedb:00000044-b-2#4166,NA,NA,p.Ala105Glu,-2.75,-2.81,2,A435E +urn:mavedb:00000044-b-2#4169,NA,NA,p.Ala105Gly,-1.31,-1.55,1,A435G +urn:mavedb:00000044-b-2#4170,NA,NA,p.Ala105Gly,-1.79,-1.55,2,A435G +urn:mavedb:00000044-b-2#4171,NA,NA,p.Ala105His,-2.49,-2.64,1,A435H +urn:mavedb:00000044-b-2#4172,NA,NA,p.Ala105His,-2.79,-2.64,2,A435H +urn:mavedb:00000044-b-2#4173,NA,NA,p.Ala105Ile,-2.14,-2.12,1,A435I +urn:mavedb:00000044-b-2#4174,NA,NA,p.Ala105Ile,-2.1,-2.12,2,A435I +urn:mavedb:00000044-b-2#4177,NA,NA,p.Ala105Leu,-2.6,-2.52,1,A435L +urn:mavedb:00000044-b-2#4178,NA,NA,p.Ala105Leu,-2.45,-2.52,2,A435L +urn:mavedb:00000044-b-2#4175,NA,NA,p.Ala105Lys,-2.86,-2.78,1,A435K +urn:mavedb:00000044-b-2#4176,NA,NA,p.Ala105Lys,-2.69,-2.78,2,A435K +urn:mavedb:00000044-b-2#4179,NA,NA,p.Ala105Met,-1.76,-1.73,1,A435M +urn:mavedb:00000044-b-2#4180,NA,NA,p.Ala105Met,-1.7,-1.73,2,A435M +urn:mavedb:00000044-b-2#4167,NA,NA,p.Ala105Phe,-2.15,-2.14,1,A435F +urn:mavedb:00000044-b-2#4168,NA,NA,p.Ala105Phe,-2.12,-2.14,2,A435F +urn:mavedb:00000044-b-2#4183,NA,NA,p.Ala105Pro,-3.05,-3.01,1,A435P +urn:mavedb:00000044-b-2#4184,NA,NA,p.Ala105Pro,-2.97,-3.01,2,A435P +urn:mavedb:00000044-b-2#4189,NA,NA,p.Ala105Ser,-0.36,-0.36,1,A435S +urn:mavedb:00000044-b-2#4190,NA,NA,p.Ala105Ser,-0.37,-0.36,2,A435S +urn:mavedb:00000044-b-2#4191,NA,NA,p.Ala105Thr,-0.66,-0.73,1,A435T +urn:mavedb:00000044-b-2#4192,NA,NA,p.Ala105Thr,-0.81,-0.73,2,A435T +urn:mavedb:00000044-b-2#4195,NA,NA,p.Ala105Trp,-1.44,-1.49,1,A435W +urn:mavedb:00000044-b-2#4196,NA,NA,p.Ala105Trp,-1.53,-1.49,2,A435W +urn:mavedb:00000044-b-2#4197,NA,NA,p.Ala105Tyr,-1.77,-1.74,1,A435Y +urn:mavedb:00000044-b-2#4198,NA,NA,p.Ala105Tyr,-1.7,-1.74,2,A435Y +urn:mavedb:00000044-b-2#4193,NA,NA,p.Ala105Val,-1.78,-1.74,1,A435V +urn:mavedb:00000044-b-2#4194,NA,NA,p.Ala105Val,-1.7,-1.74,2,A435V +urn:mavedb:00000044-b-2#559,NA,NA,p.Ala14*,-4.68,-4.62,1,A344 +urn:mavedb:00000044-b-2#560,NA,NA,p.Ala14*,-4.56,-4.62,2,A344 +urn:mavedb:00000044-b-2#5799,NA,NA,p.Ala145*,-4.34,-4.4,1,A475 +urn:mavedb:00000044-b-2#5800,NA,NA,p.Ala145*,-4.46,-4.4,2,A475 +urn:mavedb:00000044-b-2#5787,NA,NA,p.Ala145Arg,-0.23,-0.28,1,A475R +urn:mavedb:00000044-b-2#5788,NA,NA,p.Ala145Arg,-0.34,-0.28,2,A475R +urn:mavedb:00000044-b-2#5781,NA,NA,p.Ala145Asn,0.29,0.17,1,A475N +urn:mavedb:00000044-b-2#5782,NA,NA,p.Ala145Asn,0.05,0.17,2,A475N +urn:mavedb:00000044-b-2#5763,NA,NA,p.Ala145Asp,-0.13,-0.23,1,A475D +urn:mavedb:00000044-b-2#5764,NA,NA,p.Ala145Asp,-0.33,-0.23,2,A475D +urn:mavedb:00000044-b-2#5761,NA,NA,p.Ala145Cys,-0.36,-0.36,1,A475C +urn:mavedb:00000044-b-2#5762,NA,NA,p.Ala145Cys,-0.36,-0.36,2,A475C +urn:mavedb:00000044-b-2#5785,NA,NA,p.Ala145Gln,-0.22,-0.49,1,A475Q +urn:mavedb:00000044-b-2#5786,NA,NA,p.Ala145Gln,-0.75,-0.49,2,A475Q +urn:mavedb:00000044-b-2#5765,NA,NA,p.Ala145Glu,-0.13,-0.21,1,A475E +urn:mavedb:00000044-b-2#5766,NA,NA,p.Ala145Glu,-0.3,-0.21,2,A475E +urn:mavedb:00000044-b-2#5769,NA,NA,p.Ala145Gly,-0.15,-0.14,1,A475G +urn:mavedb:00000044-b-2#5770,NA,NA,p.Ala145Gly,-0.14,-0.14,2,A475G +urn:mavedb:00000044-b-2#5771,NA,NA,p.Ala145His,-1.69,-0.9,1,A475H +urn:mavedb:00000044-b-2#5772,NA,NA,p.Ala145His,-0.1,-0.9,2,A475H +urn:mavedb:00000044-b-2#5773,NA,NA,p.Ala145Ile,-0.34,-0.27,1,A475I +urn:mavedb:00000044-b-2#5774,NA,NA,p.Ala145Ile,-0.2,-0.27,2,A475I +urn:mavedb:00000044-b-2#5777,NA,NA,p.Ala145Leu,-0.34,-0.31,1,A475L +urn:mavedb:00000044-b-2#5778,NA,NA,p.Ala145Leu,-0.28,-0.31,2,A475L +urn:mavedb:00000044-b-2#5775,NA,NA,p.Ala145Lys,-0.2,-0.26,1,A475K +urn:mavedb:00000044-b-2#5776,NA,NA,p.Ala145Lys,-0.32,-0.26,2,A475K +urn:mavedb:00000044-b-2#5779,NA,NA,p.Ala145Met,-0.25,-0.16,1,A475M +urn:mavedb:00000044-b-2#5780,NA,NA,p.Ala145Met,-0.07,-0.16,2,A475M +urn:mavedb:00000044-b-2#5767,NA,NA,p.Ala145Phe,-0.18,-0.29,1,A475F +urn:mavedb:00000044-b-2#5768,NA,NA,p.Ala145Phe,-0.39,-0.29,2,A475F +urn:mavedb:00000044-b-2#5783,NA,NA,p.Ala145Pro,-1.44,-1.39,1,A475P +urn:mavedb:00000044-b-2#5784,NA,NA,p.Ala145Pro,-1.34,-1.39,2,A475P +urn:mavedb:00000044-b-2#5789,NA,NA,p.Ala145Ser,-0.17,-0.19,1,A475S +urn:mavedb:00000044-b-2#5790,NA,NA,p.Ala145Ser,-0.2,-0.19,2,A475S +urn:mavedb:00000044-b-2#5791,NA,NA,p.Ala145Thr,-0.26,-0.29,1,A475T +urn:mavedb:00000044-b-2#5792,NA,NA,p.Ala145Thr,-0.32,-0.29,2,A475T +urn:mavedb:00000044-b-2#5795,NA,NA,p.Ala145Trp,-1.53,-1.09,1,A475W +urn:mavedb:00000044-b-2#5796,NA,NA,p.Ala145Trp,-0.65,-1.09,2,A475W +urn:mavedb:00000044-b-2#5797,NA,NA,p.Ala145Tyr,-0.36,-0.44,1,A475Y +urn:mavedb:00000044-b-2#5798,NA,NA,p.Ala145Tyr,-0.52,-0.44,2,A475Y +urn:mavedb:00000044-b-2#5793,NA,NA,p.Ala145Val,-0.1,-0.21,1,A475V +urn:mavedb:00000044-b-2#5794,NA,NA,p.Ala145Val,-0.32,-0.21,2,A475V +urn:mavedb:00000044-b-2#547,NA,NA,p.Ala14Arg,-0.86,-0.84,1,A344R +urn:mavedb:00000044-b-2#548,NA,NA,p.Ala14Arg,-0.82,-0.84,2,A344R +urn:mavedb:00000044-b-2#541,NA,NA,p.Ala14Asn,-0.65,-0.65,1,A344N +urn:mavedb:00000044-b-2#542,NA,NA,p.Ala14Asn,-0.65,-0.65,2,A344N +urn:mavedb:00000044-b-2#523,NA,NA,p.Ala14Asp,-1.42,-1.48,1,A344D +urn:mavedb:00000044-b-2#524,NA,NA,p.Ala14Asp,-1.53,-1.48,2,A344D +urn:mavedb:00000044-b-2#521,NA,NA,p.Ala14Cys,-1.65,-1.54,1,A344C +urn:mavedb:00000044-b-2#522,NA,NA,p.Ala14Cys,-1.43,-1.54,2,A344C +urn:mavedb:00000044-b-2#545,NA,NA,p.Ala14Gln,-0.18,-0.2,1,A344Q +urn:mavedb:00000044-b-2#546,NA,NA,p.Ala14Gln,-0.21,-0.2,2,A344Q +urn:mavedb:00000044-b-2#525,NA,NA,p.Ala14Glu,-0.94,-0.94,1,A344E +urn:mavedb:00000044-b-2#526,NA,NA,p.Ala14Glu,-0.95,-0.94,2,A344E +urn:mavedb:00000044-b-2#529,NA,NA,p.Ala14Gly,-1.25,-1.31,1,A344G +urn:mavedb:00000044-b-2#530,NA,NA,p.Ala14Gly,-1.36,-1.31,2,A344G +urn:mavedb:00000044-b-2#531,NA,NA,p.Ala14His,-1.43,-1.41,1,A344H +urn:mavedb:00000044-b-2#532,NA,NA,p.Ala14His,-1.39,-1.41,2,A344H +urn:mavedb:00000044-b-2#533,NA,NA,p.Ala14Ile,-1.28,-1.38,1,A344I +urn:mavedb:00000044-b-2#534,NA,NA,p.Ala14Ile,-1.47,-1.38,2,A344I +urn:mavedb:00000044-b-2#537,NA,NA,p.Ala14Leu,-1.89,-1.87,1,A344L +urn:mavedb:00000044-b-2#538,NA,NA,p.Ala14Leu,-1.85,-1.87,2,A344L +urn:mavedb:00000044-b-2#535,NA,NA,p.Ala14Lys,-0.62,-0.57,1,A344K +urn:mavedb:00000044-b-2#536,NA,NA,p.Ala14Lys,-0.51,-0.57,2,A344K +urn:mavedb:00000044-b-2#539,NA,NA,p.Ala14Met,-1.19,-1.18,1,A344M +urn:mavedb:00000044-b-2#540,NA,NA,p.Ala14Met,-1.17,-1.18,2,A344M +urn:mavedb:00000044-b-2#527,NA,NA,p.Ala14Phe,-2.42,-2.39,1,A344F +urn:mavedb:00000044-b-2#528,NA,NA,p.Ala14Phe,-2.36,-2.39,2,A344F +urn:mavedb:00000044-b-2#543,NA,NA,p.Ala14Pro,-3.12,-2.98,1,A344P +urn:mavedb:00000044-b-2#544,NA,NA,p.Ala14Pro,-2.85,-2.98,2,A344P +urn:mavedb:00000044-b-2#549,NA,NA,p.Ala14Ser,-0.59,-0.62,1,A344S +urn:mavedb:00000044-b-2#550,NA,NA,p.Ala14Ser,-0.64,-0.62,2,A344S +urn:mavedb:00000044-b-2#551,NA,NA,p.Ala14Thr,-1.18,-1.23,1,A344T +urn:mavedb:00000044-b-2#552,NA,NA,p.Ala14Thr,-1.27,-1.23,2,A344T +urn:mavedb:00000044-b-2#555,NA,NA,p.Ala14Trp,-2.65,-2.6,1,A344W +urn:mavedb:00000044-b-2#556,NA,NA,p.Ala14Trp,-2.55,-2.6,2,A344W +urn:mavedb:00000044-b-2#557,NA,NA,p.Ala14Tyr,-2.08,-2.12,1,A344Y +urn:mavedb:00000044-b-2#558,NA,NA,p.Ala14Tyr,-2.15,-2.12,2,A344Y +urn:mavedb:00000044-b-2#553,NA,NA,p.Ala14Val,-1.68,-1.65,1,A344V +urn:mavedb:00000044-b-2#554,NA,NA,p.Ala14Val,-1.63,-1.65,2,A344V +urn:mavedb:00000044-b-2#719,NA,NA,p.Ala18*,-4.71,-4.62,1,A348 +urn:mavedb:00000044-b-2#720,NA,NA,p.Ala18*,-4.54,-4.62,2,A348 +urn:mavedb:00000044-b-2#707,NA,NA,p.Ala18Arg,-1.09,-1.26,1,A348R +urn:mavedb:00000044-b-2#708,NA,NA,p.Ala18Arg,-1.43,-1.26,2,A348R +urn:mavedb:00000044-b-2#701,NA,NA,p.Ala18Asn,-0.11,-0.11,1,A348N +urn:mavedb:00000044-b-2#702,NA,NA,p.Ala18Asn,-0.11,-0.11,2,A348N +urn:mavedb:00000044-b-2#683,NA,NA,p.Ala18Asp,-0.43,-0.4,1,A348D +urn:mavedb:00000044-b-2#684,NA,NA,p.Ala18Asp,-0.38,-0.4,2,A348D +urn:mavedb:00000044-b-2#681,NA,NA,p.Ala18Cys,-0.81,-1.16,1,A348C +urn:mavedb:00000044-b-2#682,NA,NA,p.Ala18Cys,-1.51,-1.16,2,A348C +urn:mavedb:00000044-b-2#705,NA,NA,p.Ala18Gln,-0.66,-0.47,1,A348Q +urn:mavedb:00000044-b-2#706,NA,NA,p.Ala18Gln,-0.28,-0.47,2,A348Q +urn:mavedb:00000044-b-2#685,NA,NA,p.Ala18Glu,-0.64,-0.64,1,A348E +urn:mavedb:00000044-b-2#686,NA,NA,p.Ala18Glu,-0.63,-0.64,2,A348E +urn:mavedb:00000044-b-2#689,NA,NA,p.Ala18Gly,-0.52,-0.55,1,A348G +urn:mavedb:00000044-b-2#690,NA,NA,p.Ala18Gly,-0.57,-0.55,2,A348G +urn:mavedb:00000044-b-2#691,NA,NA,p.Ala18His,-0.28,-0.28,1,A348H +urn:mavedb:00000044-b-2#692,NA,NA,p.Ala18His,-0.28,-0.28,2,A348H +urn:mavedb:00000044-b-2#693,NA,NA,p.Ala18Ile,-2.3,-2.4,1,A348I +urn:mavedb:00000044-b-2#694,NA,NA,p.Ala18Ile,-2.5,-2.4,2,A348I +urn:mavedb:00000044-b-2#697,NA,NA,p.Ala18Leu,-1.64,-1.75,1,A348L +urn:mavedb:00000044-b-2#698,NA,NA,p.Ala18Leu,-1.86,-1.75,2,A348L +urn:mavedb:00000044-b-2#695,NA,NA,p.Ala18Lys,-0.74,-0.76,1,A348K +urn:mavedb:00000044-b-2#696,NA,NA,p.Ala18Lys,-0.77,-0.76,2,A348K +urn:mavedb:00000044-b-2#699,NA,NA,p.Ala18Met,-1.41,-1.23,1,A348M +urn:mavedb:00000044-b-2#700,NA,NA,p.Ala18Met,-1.05,-1.23,2,A348M +urn:mavedb:00000044-b-2#687,NA,NA,p.Ala18Phe,-1.15,-1.16,1,A348F +urn:mavedb:00000044-b-2#688,NA,NA,p.Ala18Phe,-1.18,-1.16,2,A348F +urn:mavedb:00000044-b-2#703,NA,NA,p.Ala18Pro,0.36,0.4,1,A348P +urn:mavedb:00000044-b-2#704,NA,NA,p.Ala18Pro,0.43,0.4,2,A348P +urn:mavedb:00000044-b-2#709,NA,NA,p.Ala18Ser,-0.11,-0.17,1,A348S +urn:mavedb:00000044-b-2#710,NA,NA,p.Ala18Ser,-0.24,-0.17,2,A348S +urn:mavedb:00000044-b-2#711,NA,NA,p.Ala18Thr,-1.25,-1.19,1,A348T +urn:mavedb:00000044-b-2#712,NA,NA,p.Ala18Thr,-1.13,-1.19,2,A348T +urn:mavedb:00000044-b-2#715,NA,NA,p.Ala18Trp,-1.54,-1.49,1,A348W +urn:mavedb:00000044-b-2#716,NA,NA,p.Ala18Trp,-1.43,-1.49,2,A348W +urn:mavedb:00000044-b-2#717,NA,NA,p.Ala18Tyr,-0.49,-0.59,1,A348Y +urn:mavedb:00000044-b-2#718,NA,NA,p.Ala18Tyr,-0.7,-0.59,2,A348Y +urn:mavedb:00000044-b-2#713,NA,NA,p.Ala18Val,-1.28,-1.5,1,A348V +urn:mavedb:00000044-b-2#714,NA,NA,p.Ala18Val,-1.71,-1.5,2,A348V +urn:mavedb:00000044-b-2#7599,NA,NA,p.Ala190*,-3.5,-3.39,1,A520 +urn:mavedb:00000044-b-2#7600,NA,NA,p.Ala190*,-3.27,-3.39,2,A520 +urn:mavedb:00000044-b-2#7587,NA,NA,p.Ala190Arg,-0.26,-0.21,1,A520R +urn:mavedb:00000044-b-2#7588,NA,NA,p.Ala190Arg,-0.16,-0.21,2,A520R +urn:mavedb:00000044-b-2#7581,NA,NA,p.Ala190Asn,-0.16,-0.13,1,A520N +urn:mavedb:00000044-b-2#7582,NA,NA,p.Ala190Asn,-0.1,-0.13,2,A520N +urn:mavedb:00000044-b-2#7563,NA,NA,p.Ala190Asp,-0.04,-0.05,1,A520D +urn:mavedb:00000044-b-2#7564,NA,NA,p.Ala190Asp,-0.05,-0.05,2,A520D +urn:mavedb:00000044-b-2#7561,NA,NA,p.Ala190Cys,-0.13,-0.28,1,A520C +urn:mavedb:00000044-b-2#7562,NA,NA,p.Ala190Cys,-0.43,-0.28,2,A520C +urn:mavedb:00000044-b-2#7585,NA,NA,p.Ala190Gln,-2.88,-1.21,1,A520Q +urn:mavedb:00000044-b-2#7586,NA,NA,p.Ala190Gln,0.46,-1.21,2,A520Q +urn:mavedb:00000044-b-2#7565,NA,NA,p.Ala190Glu,0.02,0.01,1,A520E +urn:mavedb:00000044-b-2#7566,NA,NA,p.Ala190Glu,0,0.01,2,A520E +urn:mavedb:00000044-b-2#7569,NA,NA,p.Ala190Gly,0.09,0.29,1,A520G +urn:mavedb:00000044-b-2#7570,NA,NA,p.Ala190Gly,0.49,0.29,2,A520G +urn:mavedb:00000044-b-2#7571,NA,NA,p.Ala190His,-0.33,-0.18,1,A520H +urn:mavedb:00000044-b-2#7572,NA,NA,p.Ala190His,-0.03,-0.18,2,A520H +urn:mavedb:00000044-b-2#7573,NA,NA,p.Ala190Ile,-0.56,-0.5,1,A520I +urn:mavedb:00000044-b-2#7574,NA,NA,p.Ala190Ile,-0.45,-0.5,2,A520I +urn:mavedb:00000044-b-2#7577,NA,NA,p.Ala190Leu,-0.33,-0.4,1,A520L +urn:mavedb:00000044-b-2#7578,NA,NA,p.Ala190Leu,-0.46,-0.4,2,A520L +urn:mavedb:00000044-b-2#7575,NA,NA,p.Ala190Lys,-0.12,-0.09,1,A520K +urn:mavedb:00000044-b-2#7576,NA,NA,p.Ala190Lys,-0.07,-0.09,2,A520K +urn:mavedb:00000044-b-2#7579,NA,NA,p.Ala190Met,-0.25,-0.22,1,A520M +urn:mavedb:00000044-b-2#7580,NA,NA,p.Ala190Met,-0.2,-0.22,2,A520M +urn:mavedb:00000044-b-2#7567,NA,NA,p.Ala190Phe,-0.22,-0.38,1,A520F +urn:mavedb:00000044-b-2#7568,NA,NA,p.Ala190Phe,-0.54,-0.38,2,A520F +urn:mavedb:00000044-b-2#7583,NA,NA,p.Ala190Pro,0.08,0.05,1,A520P +urn:mavedb:00000044-b-2#7584,NA,NA,p.Ala190Pro,0.01,0.05,2,A520P +urn:mavedb:00000044-b-2#7589,NA,NA,p.Ala190Ser,-0.06,-0.05,1,A520S +urn:mavedb:00000044-b-2#7590,NA,NA,p.Ala190Ser,-0.05,-0.05,2,A520S +urn:mavedb:00000044-b-2#7591,NA,NA,p.Ala190Thr,-0.06,-0.07,1,A520T +urn:mavedb:00000044-b-2#7592,NA,NA,p.Ala190Thr,-0.08,-0.07,2,A520T +urn:mavedb:00000044-b-2#7595,NA,NA,p.Ala190Trp,-2.88,-1.75,1,A520W +urn:mavedb:00000044-b-2#7596,NA,NA,p.Ala190Trp,-0.63,-1.75,2,A520W +urn:mavedb:00000044-b-2#7597,NA,NA,p.Ala190Tyr,-0.45,-0.35,1,A520Y +urn:mavedb:00000044-b-2#7598,NA,NA,p.Ala190Tyr,-0.26,-0.35,2,A520Y +urn:mavedb:00000044-b-2#7593,NA,NA,p.Ala190Val,-0.23,-0.23,1,A520V +urn:mavedb:00000044-b-2#7594,NA,NA,p.Ala190Val,-0.22,-0.23,2,A520V +urn:mavedb:00000044-b-2#7679,NA,NA,p.Ala192*,-3.66,-3.46,1,A522 +urn:mavedb:00000044-b-2#7680,NA,NA,p.Ala192*,-3.26,-3.46,2,A522 +urn:mavedb:00000044-b-2#7667,NA,NA,p.Ala192Arg,0.05,-0.08,1,A522R +urn:mavedb:00000044-b-2#7668,NA,NA,p.Ala192Arg,-0.21,-0.08,2,A522R +urn:mavedb:00000044-b-2#7661,NA,NA,p.Ala192Asn,-0.02,-0.33,1,A522N +urn:mavedb:00000044-b-2#7662,NA,NA,p.Ala192Asn,-0.63,-0.33,2,A522N +urn:mavedb:00000044-b-2#7643,NA,NA,p.Ala192Asp,-0.13,-0.01,1,A522D +urn:mavedb:00000044-b-2#7644,NA,NA,p.Ala192Asp,0.1,-0.01,2,A522D +urn:mavedb:00000044-b-2#7641,NA,NA,p.Ala192Cys,-0.2,-0.19,1,A522C +urn:mavedb:00000044-b-2#7642,NA,NA,p.Ala192Cys,-0.18,-0.19,2,A522C +urn:mavedb:00000044-b-2#7665,NA,NA,p.Ala192Gln,-0.15,0.09,1,A522Q +urn:mavedb:00000044-b-2#7666,NA,NA,p.Ala192Gln,0.33,0.09,2,A522Q +urn:mavedb:00000044-b-2#7645,NA,NA,p.Ala192Glu,-0.02,-0.02,1,A522E +urn:mavedb:00000044-b-2#7646,NA,NA,p.Ala192Glu,-0.02,-0.02,2,A522E +urn:mavedb:00000044-b-2#7649,NA,NA,p.Ala192Gly,0.21,0.04,1,A522G +urn:mavedb:00000044-b-2#7650,NA,NA,p.Ala192Gly,-0.13,0.04,2,A522G +urn:mavedb:00000044-b-2#7651,NA,NA,p.Ala192His,-0.06,-0.17,1,A522H +urn:mavedb:00000044-b-2#7652,NA,NA,p.Ala192His,-0.27,-0.17,2,A522H +urn:mavedb:00000044-b-2#7653,NA,NA,p.Ala192Ile,-0.3,-0.14,1,A522I +urn:mavedb:00000044-b-2#7654,NA,NA,p.Ala192Ile,0.02,-0.14,2,A522I +urn:mavedb:00000044-b-2#7657,NA,NA,p.Ala192Leu,-0.3,-0.18,1,A522L +urn:mavedb:00000044-b-2#7658,NA,NA,p.Ala192Leu,-0.06,-0.18,2,A522L +urn:mavedb:00000044-b-2#7655,NA,NA,p.Ala192Lys,0.03,0.03,1,A522K +urn:mavedb:00000044-b-2#7656,NA,NA,p.Ala192Lys,0.04,0.03,2,A522K +urn:mavedb:00000044-b-2#7659,NA,NA,p.Ala192Met,0.03,-0.03,1,A522M +urn:mavedb:00000044-b-2#7660,NA,NA,p.Ala192Met,-0.09,-0.03,2,A522M +urn:mavedb:00000044-b-2#7647,NA,NA,p.Ala192Phe,0.1,-0.65,1,A522F +urn:mavedb:00000044-b-2#7648,NA,NA,p.Ala192Phe,-1.4,-0.65,2,A522F +urn:mavedb:00000044-b-2#7663,NA,NA,p.Ala192Pro,-0.04,-0.27,1,A522P +urn:mavedb:00000044-b-2#7664,NA,NA,p.Ala192Pro,-0.5,-0.27,2,A522P +urn:mavedb:00000044-b-2#7669,NA,NA,p.Ala192Ser,-0.02,-0.01,1,A522S +urn:mavedb:00000044-b-2#7670,NA,NA,p.Ala192Ser,-0.01,-0.01,2,A522S +urn:mavedb:00000044-b-2#7671,NA,NA,p.Ala192Thr,0,-0.02,1,A522T +urn:mavedb:00000044-b-2#7672,NA,NA,p.Ala192Thr,-0.03,-0.02,2,A522T +urn:mavedb:00000044-b-2#7675,NA,NA,p.Ala192Trp,-0.38,-0.38,1,A522W +urn:mavedb:00000044-b-2#7676,NA,NA,p.Ala192Trp,-0.39,-0.38,2,A522W +urn:mavedb:00000044-b-2#7677,NA,NA,p.Ala192Tyr,0.24,0.2,1,A522Y +urn:mavedb:00000044-b-2#7678,NA,NA,p.Ala192Tyr,0.17,0.2,2,A522Y +urn:mavedb:00000044-b-2#7673,NA,NA,p.Ala192Val,-0.02,-0.07,1,A522V +urn:mavedb:00000044-b-2#7674,NA,NA,p.Ala192Val,-0.12,-0.07,2,A522V +urn:mavedb:00000044-b-2#879,NA,NA,p.Ala22*,-4.67,-4.62,1,A352 +urn:mavedb:00000044-b-2#880,NA,NA,p.Ala22*,-4.56,-4.62,2,A352 +urn:mavedb:00000044-b-2#867,NA,NA,p.Ala22Arg,-0.46,-0.49,1,A352R +urn:mavedb:00000044-b-2#868,NA,NA,p.Ala22Arg,-0.53,-0.49,2,A352R +urn:mavedb:00000044-b-2#861,NA,NA,p.Ala22Asn,-0.35,-0.4,1,A352N +urn:mavedb:00000044-b-2#862,NA,NA,p.Ala22Asn,-0.45,-0.4,2,A352N +urn:mavedb:00000044-b-2#843,NA,NA,p.Ala22Asp,-0.36,-0.45,1,A352D +urn:mavedb:00000044-b-2#844,NA,NA,p.Ala22Asp,-0.54,-0.45,2,A352D +urn:mavedb:00000044-b-2#841,NA,NA,p.Ala22Cys,-0.83,-0.57,1,A352C +urn:mavedb:00000044-b-2#842,NA,NA,p.Ala22Cys,-0.31,-0.57,2,A352C +urn:mavedb:00000044-b-2#865,NA,NA,p.Ala22Gln,-0.57,-0.6,1,A352Q +urn:mavedb:00000044-b-2#866,NA,NA,p.Ala22Gln,-0.63,-0.6,2,A352Q +urn:mavedb:00000044-b-2#845,NA,NA,p.Ala22Glu,-0.2,-0.2,1,A352E +urn:mavedb:00000044-b-2#846,NA,NA,p.Ala22Glu,-0.2,-0.2,2,A352E +urn:mavedb:00000044-b-2#849,NA,NA,p.Ala22Gly,-1.17,-0.98,1,A352G +urn:mavedb:00000044-b-2#850,NA,NA,p.Ala22Gly,-0.79,-0.98,2,A352G +urn:mavedb:00000044-b-2#851,NA,NA,p.Ala22His,-0.25,-0.42,1,A352H +urn:mavedb:00000044-b-2#852,NA,NA,p.Ala22His,-0.59,-0.42,2,A352H +urn:mavedb:00000044-b-2#853,NA,NA,p.Ala22Ile,-2.15,-1.96,1,A352I +urn:mavedb:00000044-b-2#854,NA,NA,p.Ala22Ile,-1.77,-1.96,2,A352I +urn:mavedb:00000044-b-2#857,NA,NA,p.Ala22Leu,-1.35,-1.25,1,A352L +urn:mavedb:00000044-b-2#858,NA,NA,p.Ala22Leu,-1.15,-1.25,2,A352L +urn:mavedb:00000044-b-2#855,NA,NA,p.Ala22Lys,-0.34,-0.41,1,A352K +urn:mavedb:00000044-b-2#856,NA,NA,p.Ala22Lys,-0.49,-0.41,2,A352K +urn:mavedb:00000044-b-2#859,NA,NA,p.Ala22Met,-1.37,-0.94,1,A352M +urn:mavedb:00000044-b-2#860,NA,NA,p.Ala22Met,-0.52,-0.94,2,A352M +urn:mavedb:00000044-b-2#847,NA,NA,p.Ala22Phe,-1.39,-1.1,1,A352F +urn:mavedb:00000044-b-2#848,NA,NA,p.Ala22Phe,-0.81,-1.1,2,A352F +urn:mavedb:00000044-b-2#863,NA,NA,p.Ala22Pro,-2.29,-2.42,1,A352P +urn:mavedb:00000044-b-2#864,NA,NA,p.Ala22Pro,-2.55,-2.42,2,A352P +urn:mavedb:00000044-b-2#869,NA,NA,p.Ala22Ser,-0.33,-0.26,1,A352S +urn:mavedb:00000044-b-2#870,NA,NA,p.Ala22Ser,-0.19,-0.26,2,A352S +urn:mavedb:00000044-b-2#871,NA,NA,p.Ala22Thr,-1.09,-1.24,1,A352T +urn:mavedb:00000044-b-2#872,NA,NA,p.Ala22Thr,-1.38,-1.24,2,A352T +urn:mavedb:00000044-b-2#875,NA,NA,p.Ala22Trp,-1.24,-1.35,1,A352W +urn:mavedb:00000044-b-2#876,NA,NA,p.Ala22Trp,-1.46,-1.35,2,A352W +urn:mavedb:00000044-b-2#877,NA,NA,p.Ala22Tyr,-0.63,-0.79,1,A352Y +urn:mavedb:00000044-b-2#878,NA,NA,p.Ala22Tyr,-0.94,-0.79,2,A352Y +urn:mavedb:00000044-b-2#873,NA,NA,p.Ala22Val,-1.82,-1.79,1,A352V +urn:mavedb:00000044-b-2#874,NA,NA,p.Ala22Val,-1.77,-1.79,2,A352V +urn:mavedb:00000044-b-2#1319,NA,NA,p.Ala33*,-4.66,-4.6,1,A363 +urn:mavedb:00000044-b-2#1320,NA,NA,p.Ala33*,-4.54,-4.6,2,A363 +urn:mavedb:00000044-b-2#1307,NA,NA,p.Ala33Arg,-1.43,-1.49,1,A363R +urn:mavedb:00000044-b-2#1308,NA,NA,p.Ala33Arg,-1.54,-1.49,2,A363R +urn:mavedb:00000044-b-2#1301,NA,NA,p.Ala33Asn,-3.34,-2.44,1,A363N +urn:mavedb:00000044-b-2#1302,NA,NA,p.Ala33Asn,-1.54,-2.44,2,A363N +urn:mavedb:00000044-b-2#1283,NA,NA,p.Ala33Asp,-3.27,-3.22,1,A363D +urn:mavedb:00000044-b-2#1284,NA,NA,p.Ala33Asp,-3.18,-3.22,2,A363D +urn:mavedb:00000044-b-2#1281,NA,NA,p.Ala33Cys,-0.14,-0.23,1,A363C +urn:mavedb:00000044-b-2#1282,NA,NA,p.Ala33Cys,-0.33,-0.23,2,A363C +urn:mavedb:00000044-b-2#1305,NA,NA,p.Ala33Gln,-0.18,-0.34,1,A363Q +urn:mavedb:00000044-b-2#1306,NA,NA,p.Ala33Gln,-0.49,-0.34,2,A363Q +urn:mavedb:00000044-b-2#1285,NA,NA,p.Ala33Glu,-1.63,-1.38,1,A363E +urn:mavedb:00000044-b-2#1286,NA,NA,p.Ala33Glu,-1.14,-1.38,2,A363E +urn:mavedb:00000044-b-2#1289,NA,NA,p.Ala33Gly,-0.37,-0.37,1,A363G +urn:mavedb:00000044-b-2#1290,NA,NA,p.Ala33Gly,-0.37,-0.37,2,A363G +urn:mavedb:00000044-b-2#1291,NA,NA,p.Ala33His,-0.85,-0.86,1,A363H +urn:mavedb:00000044-b-2#1292,NA,NA,p.Ala33His,-0.87,-0.86,2,A363H +urn:mavedb:00000044-b-2#1293,NA,NA,p.Ala33Ile,-0.98,-0.96,1,A363I +urn:mavedb:00000044-b-2#1294,NA,NA,p.Ala33Ile,-0.93,-0.96,2,A363I +urn:mavedb:00000044-b-2#1297,NA,NA,p.Ala33Leu,-0.27,-0.32,1,A363L +urn:mavedb:00000044-b-2#1298,NA,NA,p.Ala33Leu,-0.36,-0.32,2,A363L +urn:mavedb:00000044-b-2#1295,NA,NA,p.Ala33Lys,-1.51,-1.6,1,A363K +urn:mavedb:00000044-b-2#1296,NA,NA,p.Ala33Lys,-1.68,-1.6,2,A363K +urn:mavedb:00000044-b-2#1299,NA,NA,p.Ala33Met,-0.43,-0.43,1,A363M +urn:mavedb:00000044-b-2#1300,NA,NA,p.Ala33Met,-0.43,-0.43,2,A363M +urn:mavedb:00000044-b-2#1287,NA,NA,p.Ala33Phe,-0.12,-0.22,1,A363F +urn:mavedb:00000044-b-2#1288,NA,NA,p.Ala33Phe,-0.33,-0.22,2,A363F +urn:mavedb:00000044-b-2#1303,NA,NA,p.Ala33Pro,-0.42,-0.45,1,A363P +urn:mavedb:00000044-b-2#1304,NA,NA,p.Ala33Pro,-0.48,-0.45,2,A363P +urn:mavedb:00000044-b-2#1309,NA,NA,p.Ala33Ser,-0.86,-0.89,1,A363S +urn:mavedb:00000044-b-2#1310,NA,NA,p.Ala33Ser,-0.92,-0.89,2,A363S +urn:mavedb:00000044-b-2#1311,NA,NA,p.Ala33Thr,-0.9,-0.89,1,A363T +urn:mavedb:00000044-b-2#1312,NA,NA,p.Ala33Thr,-0.88,-0.89,2,A363T +urn:mavedb:00000044-b-2#1315,NA,NA,p.Ala33Trp,0.33,0.25,1,A363W +urn:mavedb:00000044-b-2#1316,NA,NA,p.Ala33Trp,0.17,0.25,2,A363W +urn:mavedb:00000044-b-2#1317,NA,NA,p.Ala33Tyr,-0.54,-0.49,1,A363Y +urn:mavedb:00000044-b-2#1318,NA,NA,p.Ala33Tyr,-0.44,-0.49,2,A363Y +urn:mavedb:00000044-b-2#1313,NA,NA,p.Ala33Val,-0.37,-0.41,1,A363V +urn:mavedb:00000044-b-2#1314,NA,NA,p.Ala33Val,-0.46,-0.41,2,A363V +urn:mavedb:00000044-b-2#1679,NA,NA,p.Ala42*,-4.64,-4.59,1,A372 +urn:mavedb:00000044-b-2#1680,NA,NA,p.Ala42*,-4.53,-4.59,2,A372 +urn:mavedb:00000044-b-2#1667,NA,NA,p.Ala42Arg,0.12,0.05,1,A372R +urn:mavedb:00000044-b-2#1668,NA,NA,p.Ala42Arg,-0.02,0.05,2,A372R +urn:mavedb:00000044-b-2#1661,NA,NA,p.Ala42Asn,-0.88,-0.9,1,A372N +urn:mavedb:00000044-b-2#1662,NA,NA,p.Ala42Asn,-0.93,-0.9,2,A372N +urn:mavedb:00000044-b-2#1643,NA,NA,p.Ala42Asp,-0.2,-0.28,1,A372D +urn:mavedb:00000044-b-2#1644,NA,NA,p.Ala42Asp,-0.35,-0.28,2,A372D +urn:mavedb:00000044-b-2#1641,NA,NA,p.Ala42Cys,-1.32,-1.01,1,A372C +urn:mavedb:00000044-b-2#1642,NA,NA,p.Ala42Cys,-0.7,-1.01,2,A372C +urn:mavedb:00000044-b-2#1665,NA,NA,p.Ala42Gln,0.06,0.2,1,A372Q +urn:mavedb:00000044-b-2#1666,NA,NA,p.Ala42Gln,0.34,0.2,2,A372Q +urn:mavedb:00000044-b-2#1645,NA,NA,p.Ala42Glu,0.09,0.08,1,A372E +urn:mavedb:00000044-b-2#1646,NA,NA,p.Ala42Glu,0.07,0.08,2,A372E +urn:mavedb:00000044-b-2#1649,NA,NA,p.Ala42Gly,-0.01,-0.01,1,A372G +urn:mavedb:00000044-b-2#1650,NA,NA,p.Ala42Gly,-0.01,-0.01,2,A372G +urn:mavedb:00000044-b-2#1651,NA,NA,p.Ala42His,-0.1,-0.38,1,A372H +urn:mavedb:00000044-b-2#1652,NA,NA,p.Ala42His,-0.67,-0.38,2,A372H +urn:mavedb:00000044-b-2#1653,NA,NA,p.Ala42Ile,-0.55,-0.69,1,A372I +urn:mavedb:00000044-b-2#1654,NA,NA,p.Ala42Ile,-0.82,-0.69,2,A372I +urn:mavedb:00000044-b-2#1657,NA,NA,p.Ala42Leu,-0.57,-0.66,1,A372L +urn:mavedb:00000044-b-2#1658,NA,NA,p.Ala42Leu,-0.75,-0.66,2,A372L +urn:mavedb:00000044-b-2#1655,NA,NA,p.Ala42Lys,0.27,0.25,1,A372K +urn:mavedb:00000044-b-2#1656,NA,NA,p.Ala42Lys,0.23,0.25,2,A372K +urn:mavedb:00000044-b-2#1659,NA,NA,p.Ala42Met,0,-0.1,1,A372M +urn:mavedb:00000044-b-2#1660,NA,NA,p.Ala42Met,-0.19,-0.1,2,A372M +urn:mavedb:00000044-b-2#1647,NA,NA,p.Ala42Phe,-0.49,-0.51,1,A372F +urn:mavedb:00000044-b-2#1648,NA,NA,p.Ala42Phe,-0.52,-0.51,2,A372F +urn:mavedb:00000044-b-2#1663,NA,NA,p.Ala42Pro,-0.13,-0.22,1,A372P +urn:mavedb:00000044-b-2#1664,NA,NA,p.Ala42Pro,-0.31,-0.22,2,A372P +urn:mavedb:00000044-b-2#1669,NA,NA,p.Ala42Ser,-0.48,-0.45,1,A372S +urn:mavedb:00000044-b-2#1670,NA,NA,p.Ala42Ser,-0.43,-0.45,2,A372S +urn:mavedb:00000044-b-2#1671,NA,NA,p.Ala42Thr,-0.28,-0.28,1,A372T +urn:mavedb:00000044-b-2#1672,NA,NA,p.Ala42Thr,-0.28,-0.28,2,A372T +urn:mavedb:00000044-b-2#1675,NA,NA,p.Ala42Trp,-0.53,-0.52,1,A372W +urn:mavedb:00000044-b-2#1676,NA,NA,p.Ala42Trp,-0.52,-0.52,2,A372W +urn:mavedb:00000044-b-2#1677,NA,NA,p.Ala42Tyr,-0.82,-0.87,1,A372Y +urn:mavedb:00000044-b-2#1678,NA,NA,p.Ala42Tyr,-0.91,-0.87,2,A372Y +urn:mavedb:00000044-b-2#1673,NA,NA,p.Ala42Val,-0.37,-0.49,1,A372V +urn:mavedb:00000044-b-2#1674,NA,NA,p.Ala42Val,-0.61,-0.49,2,A372V +urn:mavedb:00000044-b-2#2679,NA,NA,p.Ala67*,NA,NA,1,A397 +urn:mavedb:00000044-b-2#2680,NA,NA,p.Ala67*,NA,NA,2,A397 +urn:mavedb:00000044-b-2#2667,NA,NA,p.Ala67Arg,-2.86,-2.68,1,A397R +urn:mavedb:00000044-b-2#2668,NA,NA,p.Ala67Arg,-2.51,-2.68,2,A397R +urn:mavedb:00000044-b-2#2661,NA,NA,p.Ala67Asn,-2.37,-2.27,1,A397N +urn:mavedb:00000044-b-2#2662,NA,NA,p.Ala67Asn,-2.16,-2.27,2,A397N +urn:mavedb:00000044-b-2#2643,NA,NA,p.Ala67Asp,-3,-2.9,1,A397D +urn:mavedb:00000044-b-2#2644,NA,NA,p.Ala67Asp,-2.8,-2.9,2,A397D +urn:mavedb:00000044-b-2#2641,NA,NA,p.Ala67Cys,-0.42,-0.4,1,A397C +urn:mavedb:00000044-b-2#2642,NA,NA,p.Ala67Cys,-0.39,-0.4,2,A397C +urn:mavedb:00000044-b-2#2666,NA,NA,p.Ala67Gln,NA,NA,2,A397Q +urn:mavedb:00000044-b-2#2665,NA,NA,p.Ala67Gln,NA,NA,1,A397Q +urn:mavedb:00000044-b-2#2645,NA,NA,p.Ala67Glu,NA,NA,1,A397E +urn:mavedb:00000044-b-2#2646,NA,NA,p.Ala67Glu,NA,NA,2,A397E +urn:mavedb:00000044-b-2#2649,NA,NA,p.Ala67Gly,-2.6,-2.58,1,A397G +urn:mavedb:00000044-b-2#2650,NA,NA,p.Ala67Gly,-2.57,-2.58,2,A397G +urn:mavedb:00000044-b-2#2651,NA,NA,p.Ala67His,-2.86,-2.75,1,A397H +urn:mavedb:00000044-b-2#2652,NA,NA,p.Ala67His,-2.64,-2.75,2,A397H +urn:mavedb:00000044-b-2#2653,NA,NA,p.Ala67Ile,-0.51,-0.57,1,A397I +urn:mavedb:00000044-b-2#2654,NA,NA,p.Ala67Ile,-0.63,-0.57,2,A397I +urn:mavedb:00000044-b-2#2657,NA,NA,p.Ala67Leu,-0.04,-0.07,1,A397L +urn:mavedb:00000044-b-2#2658,NA,NA,p.Ala67Leu,-0.1,-0.07,2,A397L +urn:mavedb:00000044-b-2#2655,NA,NA,p.Ala67Lys,NA,NA,1,A397K +urn:mavedb:00000044-b-2#2656,NA,NA,p.Ala67Lys,NA,NA,2,A397K +urn:mavedb:00000044-b-2#2659,NA,NA,p.Ala67Met,NA,NA,1,A397M +urn:mavedb:00000044-b-2#2660,NA,NA,p.Ala67Met,NA,NA,2,A397M +urn:mavedb:00000044-b-2#2647,NA,NA,p.Ala67Phe,-1.6,-1.51,1,A397F +urn:mavedb:00000044-b-2#2648,NA,NA,p.Ala67Phe,-1.41,-1.51,2,A397F +urn:mavedb:00000044-b-2#2663,NA,NA,p.Ala67Pro,-2.87,-2.76,1,A397P +urn:mavedb:00000044-b-2#2664,NA,NA,p.Ala67Pro,-2.65,-2.76,2,A397P +urn:mavedb:00000044-b-2#2669,NA,NA,p.Ala67Ser,-2.26,-2.18,1,A397S +urn:mavedb:00000044-b-2#2670,NA,NA,p.Ala67Ser,-2.09,-2.18,2,A397S +urn:mavedb:00000044-b-2#2671,NA,NA,p.Ala67Thr,-1.45,-1.55,1,A397T +urn:mavedb:00000044-b-2#2672,NA,NA,p.Ala67Thr,-1.66,-1.55,2,A397T +urn:mavedb:00000044-b-2#2675,NA,NA,p.Ala67Trp,NA,NA,1,A397W +urn:mavedb:00000044-b-2#2676,NA,NA,p.Ala67Trp,NA,NA,2,A397W +urn:mavedb:00000044-b-2#2677,NA,NA,p.Ala67Tyr,-2.35,-2.19,1,A397Y +urn:mavedb:00000044-b-2#2678,NA,NA,p.Ala67Tyr,-2.02,-2.19,2,A397Y +urn:mavedb:00000044-b-2#2673,NA,NA,p.Ala67Val,-0.52,-0.45,1,A397V +urn:mavedb:00000044-b-2#2674,NA,NA,p.Ala67Val,-0.38,-0.45,2,A397V +urn:mavedb:00000044-b-2#3239,NA,NA,p.Ala81*,-4.61,-4.55,1,A411 +urn:mavedb:00000044-b-2#3240,NA,NA,p.Ala81*,-4.49,-4.55,2,A411 +urn:mavedb:00000044-b-2#3227,NA,NA,p.Ala81Arg,-0.89,-0.98,1,A411R +urn:mavedb:00000044-b-2#3228,NA,NA,p.Ala81Arg,-1.07,-0.98,2,A411R +urn:mavedb:00000044-b-2#3221,NA,NA,p.Ala81Asn,-2.34,-2.18,1,A411N +urn:mavedb:00000044-b-2#3222,NA,NA,p.Ala81Asn,-2.03,-2.18,2,A411N +urn:mavedb:00000044-b-2#3203,NA,NA,p.Ala81Asp,-2.06,-2.02,1,A411D +urn:mavedb:00000044-b-2#3204,NA,NA,p.Ala81Asp,-1.97,-2.02,2,A411D +urn:mavedb:00000044-b-2#3201,NA,NA,p.Ala81Cys,-1.57,-1.58,1,A411C +urn:mavedb:00000044-b-2#3202,NA,NA,p.Ala81Cys,-1.58,-1.58,2,A411C +urn:mavedb:00000044-b-2#3225,NA,NA,p.Ala81Gln,-0.35,-0.54,1,A411Q +urn:mavedb:00000044-b-2#3226,NA,NA,p.Ala81Gln,-0.73,-0.54,2,A411Q +urn:mavedb:00000044-b-2#3205,NA,NA,p.Ala81Glu,-0.89,-0.79,1,A411E +urn:mavedb:00000044-b-2#3206,NA,NA,p.Ala81Glu,-0.68,-0.79,2,A411E +urn:mavedb:00000044-b-2#3209,NA,NA,p.Ala81Gly,-0.88,-0.78,1,A411G +urn:mavedb:00000044-b-2#3210,NA,NA,p.Ala81Gly,-0.69,-0.78,2,A411G +urn:mavedb:00000044-b-2#3211,NA,NA,p.Ala81His,-1.99,-2.03,1,A411H +urn:mavedb:00000044-b-2#3212,NA,NA,p.Ala81His,-2.06,-2.03,2,A411H +urn:mavedb:00000044-b-2#3213,NA,NA,p.Ala81Ile,-2.35,-2.23,1,A411I +urn:mavedb:00000044-b-2#3214,NA,NA,p.Ala81Ile,-2.1,-2.23,2,A411I +urn:mavedb:00000044-b-2#3217,NA,NA,p.Ala81Leu,-2.34,-2.3,1,A411L +urn:mavedb:00000044-b-2#3218,NA,NA,p.Ala81Leu,-2.26,-2.3,2,A411L +urn:mavedb:00000044-b-2#3215,NA,NA,p.Ala81Lys,-1.18,-1.32,1,A411K +urn:mavedb:00000044-b-2#3216,NA,NA,p.Ala81Lys,-1.45,-1.32,2,A411K +urn:mavedb:00000044-b-2#3219,NA,NA,p.Ala81Met,-1.55,-1.62,1,A411M +urn:mavedb:00000044-b-2#3220,NA,NA,p.Ala81Met,-1.69,-1.62,2,A411M +urn:mavedb:00000044-b-2#3207,NA,NA,p.Ala81Phe,-2.41,-2.35,1,A411F +urn:mavedb:00000044-b-2#3208,NA,NA,p.Ala81Phe,-2.28,-2.35,2,A411F +urn:mavedb:00000044-b-2#3223,NA,NA,p.Ala81Pro,-2.85,-2.77,1,A411P +urn:mavedb:00000044-b-2#3224,NA,NA,p.Ala81Pro,-2.68,-2.77,2,A411P +urn:mavedb:00000044-b-2#3229,NA,NA,p.Ala81Ser,-0.68,-0.73,1,A411S +urn:mavedb:00000044-b-2#3230,NA,NA,p.Ala81Ser,-0.78,-0.73,2,A411S +urn:mavedb:00000044-b-2#3231,NA,NA,p.Ala81Thr,-1.61,-1.59,1,A411T +urn:mavedb:00000044-b-2#3232,NA,NA,p.Ala81Thr,-1.57,-1.59,2,A411T +urn:mavedb:00000044-b-2#3235,NA,NA,p.Ala81Trp,-1.05,-1.16,1,A411W +urn:mavedb:00000044-b-2#3236,NA,NA,p.Ala81Trp,-1.27,-1.16,2,A411W +urn:mavedb:00000044-b-2#3237,NA,NA,p.Ala81Tyr,-2.34,-2.33,1,A411Y +urn:mavedb:00000044-b-2#3238,NA,NA,p.Ala81Tyr,-2.33,-2.33,2,A411Y +urn:mavedb:00000044-b-2#3233,NA,NA,p.Ala81Val,-1.42,-1.54,1,A411V +urn:mavedb:00000044-b-2#3234,NA,NA,p.Ala81Val,-1.67,-1.54,2,A411V +urn:mavedb:00000044-b-2#3559,NA,NA,p.Ala89*,-4.63,-4.56,1,A419 +urn:mavedb:00000044-b-2#3560,NA,NA,p.Ala89*,-4.49,-4.56,2,A419 +urn:mavedb:00000044-b-2#3547,NA,NA,p.Ala89Arg,-2.5,-2.51,1,A419R +urn:mavedb:00000044-b-2#3548,NA,NA,p.Ala89Arg,-2.52,-2.51,2,A419R +urn:mavedb:00000044-b-2#3541,NA,NA,p.Ala89Asn,-2.29,-2.1,1,A419N +urn:mavedb:00000044-b-2#3542,NA,NA,p.Ala89Asn,-1.92,-2.1,2,A419N +urn:mavedb:00000044-b-2#3523,NA,NA,p.Ala89Asp,-2.54,-2.53,1,A419D +urn:mavedb:00000044-b-2#3524,NA,NA,p.Ala89Asp,-2.53,-2.53,2,A419D +urn:mavedb:00000044-b-2#3521,NA,NA,p.Ala89Cys,-1.21,-1.29,1,A419C +urn:mavedb:00000044-b-2#3522,NA,NA,p.Ala89Cys,-1.38,-1.29,2,A419C +urn:mavedb:00000044-b-2#3545,NA,NA,p.Ala89Gln,-2.25,-2.08,1,A419Q +urn:mavedb:00000044-b-2#3546,NA,NA,p.Ala89Gln,-1.91,-2.08,2,A419Q +urn:mavedb:00000044-b-2#3525,NA,NA,p.Ala89Glu,-2.72,-2.58,1,A419E +urn:mavedb:00000044-b-2#3526,NA,NA,p.Ala89Glu,-2.44,-2.58,2,A419E +urn:mavedb:00000044-b-2#3529,NA,NA,p.Ala89Gly,-1.92,-1.88,1,A419G +urn:mavedb:00000044-b-2#3530,NA,NA,p.Ala89Gly,-1.84,-1.88,2,A419G +urn:mavedb:00000044-b-2#3531,NA,NA,p.Ala89His,-2.29,-2.25,1,A419H +urn:mavedb:00000044-b-2#3532,NA,NA,p.Ala89His,-2.21,-2.25,2,A419H +urn:mavedb:00000044-b-2#3533,NA,NA,p.Ala89Ile,-2.41,-2.28,1,A419I +urn:mavedb:00000044-b-2#3534,NA,NA,p.Ala89Ile,-2.15,-2.28,2,A419I +urn:mavedb:00000044-b-2#3537,NA,NA,p.Ala89Leu,-2.66,-2.65,1,A419L +urn:mavedb:00000044-b-2#3538,NA,NA,p.Ala89Leu,-2.63,-2.65,2,A419L +urn:mavedb:00000044-b-2#3535,NA,NA,p.Ala89Lys,-2.55,-2.51,1,A419K +urn:mavedb:00000044-b-2#3536,NA,NA,p.Ala89Lys,-2.48,-2.51,2,A419K +urn:mavedb:00000044-b-2#3539,NA,NA,p.Ala89Met,-2.36,-2.41,1,A419M +urn:mavedb:00000044-b-2#3540,NA,NA,p.Ala89Met,-2.46,-2.41,2,A419M +urn:mavedb:00000044-b-2#3527,NA,NA,p.Ala89Phe,-2.79,-2.64,1,A419F +urn:mavedb:00000044-b-2#3528,NA,NA,p.Ala89Phe,-2.5,-2.64,2,A419F +urn:mavedb:00000044-b-2#3543,NA,NA,p.Ala89Pro,-0.8,-0.81,1,A419P +urn:mavedb:00000044-b-2#3544,NA,NA,p.Ala89Pro,-0.82,-0.81,2,A419P +urn:mavedb:00000044-b-2#3549,NA,NA,p.Ala89Ser,-0.73,-0.68,1,A419S +urn:mavedb:00000044-b-2#3550,NA,NA,p.Ala89Ser,-0.63,-0.68,2,A419S +urn:mavedb:00000044-b-2#3551,NA,NA,p.Ala89Thr,-1.19,-1.21,1,A419T +urn:mavedb:00000044-b-2#3552,NA,NA,p.Ala89Thr,-1.23,-1.21,2,A419T +urn:mavedb:00000044-b-2#3555,NA,NA,p.Ala89Trp,-2.93,-2.84,1,A419W +urn:mavedb:00000044-b-2#3556,NA,NA,p.Ala89Trp,-2.76,-2.84,2,A419W +urn:mavedb:00000044-b-2#3557,NA,NA,p.Ala89Tyr,-2.49,-2.41,1,A419Y +urn:mavedb:00000044-b-2#3558,NA,NA,p.Ala89Tyr,-2.33,-2.41,2,A419Y +urn:mavedb:00000044-b-2#3553,NA,NA,p.Ala89Val,-1.63,-1.64,1,A419V +urn:mavedb:00000044-b-2#3554,NA,NA,p.Ala89Val,-1.65,-1.64,2,A419V +urn:mavedb:00000044-b-2#4959,NA,NA,p.Arg124*,-4.63,-4.58,1,R454 +urn:mavedb:00000044-b-2#4960,NA,NA,p.Arg124*,-4.54,-4.58,2,R454 +urn:mavedb:00000044-b-2#4921,NA,NA,p.Arg124Ala,-2.53,-2.64,1,R454A +urn:mavedb:00000044-b-2#4922,NA,NA,p.Arg124Ala,-2.74,-2.64,2,R454A +urn:mavedb:00000044-b-2#4943,NA,NA,p.Arg124Asn,-2.49,-2.55,1,R454N +urn:mavedb:00000044-b-2#4944,NA,NA,p.Arg124Asn,-2.61,-2.55,2,R454N +urn:mavedb:00000044-b-2#4925,NA,NA,p.Arg124Asp,-2.6,-2.43,1,R454D +urn:mavedb:00000044-b-2#4926,NA,NA,p.Arg124Asp,-2.26,-2.43,2,R454D +urn:mavedb:00000044-b-2#4923,NA,NA,p.Arg124Cys,-2.38,-2.33,1,R454C +urn:mavedb:00000044-b-2#4924,NA,NA,p.Arg124Cys,-2.29,-2.33,2,R454C +urn:mavedb:00000044-b-2#4947,NA,NA,p.Arg124Gln,-2.56,-2.48,1,R454Q +urn:mavedb:00000044-b-2#4948,NA,NA,p.Arg124Gln,-2.39,-2.48,2,R454Q +urn:mavedb:00000044-b-2#4927,NA,NA,p.Arg124Glu,-2.38,-2.38,1,R454E +urn:mavedb:00000044-b-2#4928,NA,NA,p.Arg124Glu,-2.39,-2.38,2,R454E +urn:mavedb:00000044-b-2#4931,NA,NA,p.Arg124Gly,-2.54,-2.4,1,R454G +urn:mavedb:00000044-b-2#4932,NA,NA,p.Arg124Gly,-2.27,-2.4,2,R454G +urn:mavedb:00000044-b-2#4933,NA,NA,p.Arg124His,-2.45,-2.42,1,R454H +urn:mavedb:00000044-b-2#4934,NA,NA,p.Arg124His,-2.4,-2.42,2,R454H +urn:mavedb:00000044-b-2#4935,NA,NA,p.Arg124Ile,-0.85,-1.58,1,R454I +urn:mavedb:00000044-b-2#4936,NA,NA,p.Arg124Ile,-2.3,-1.58,2,R454I +urn:mavedb:00000044-b-2#4939,NA,NA,p.Arg124Leu,-2.11,-2.15,1,R454L +urn:mavedb:00000044-b-2#4940,NA,NA,p.Arg124Leu,-2.19,-2.15,2,R454L +urn:mavedb:00000044-b-2#4937,NA,NA,p.Arg124Lys,-2.26,-2.19,1,R454K +urn:mavedb:00000044-b-2#4938,NA,NA,p.Arg124Lys,-2.12,-2.19,2,R454K +urn:mavedb:00000044-b-2#4941,NA,NA,p.Arg124Met,-2.33,-2.42,1,R454M +urn:mavedb:00000044-b-2#4942,NA,NA,p.Arg124Met,-2.51,-2.42,2,R454M +urn:mavedb:00000044-b-2#4929,NA,NA,p.Arg124Phe,-2.3,-2.1,1,R454F +urn:mavedb:00000044-b-2#4930,NA,NA,p.Arg124Phe,-1.9,-2.1,2,R454F +urn:mavedb:00000044-b-2#4945,NA,NA,p.Arg124Pro,-2.71,-2.63,1,R454P +urn:mavedb:00000044-b-2#4946,NA,NA,p.Arg124Pro,-2.55,-2.63,2,R454P +urn:mavedb:00000044-b-2#4949,NA,NA,p.Arg124Ser,-2.51,-2.49,1,R454S +urn:mavedb:00000044-b-2#4950,NA,NA,p.Arg124Ser,-2.47,-2.49,2,R454S +urn:mavedb:00000044-b-2#4951,NA,NA,p.Arg124Thr,-2.53,-2.49,1,R454T +urn:mavedb:00000044-b-2#4952,NA,NA,p.Arg124Thr,-2.44,-2.49,2,R454T +urn:mavedb:00000044-b-2#4955,NA,NA,p.Arg124Trp,-2.83,-2.6,1,R454W +urn:mavedb:00000044-b-2#4956,NA,NA,p.Arg124Trp,-2.37,-2.6,2,R454W +urn:mavedb:00000044-b-2#4957,NA,NA,p.Arg124Tyr,-2.66,-2.59,1,R454Y +urn:mavedb:00000044-b-2#4958,NA,NA,p.Arg124Tyr,-2.52,-2.59,2,R454Y +urn:mavedb:00000044-b-2#4953,NA,NA,p.Arg124Val,-2.38,-2.27,1,R454V +urn:mavedb:00000044-b-2#4954,NA,NA,p.Arg124Val,-2.16,-2.27,2,R454V +urn:mavedb:00000044-b-2#5079,NA,NA,p.Arg127*,-4.64,-4.6,1,R457 +urn:mavedb:00000044-b-2#5080,NA,NA,p.Arg127*,-4.56,-4.6,2,R457 +urn:mavedb:00000044-b-2#5041,NA,NA,p.Arg127Ala,-1.47,-1.6,1,R457A +urn:mavedb:00000044-b-2#5042,NA,NA,p.Arg127Ala,-1.72,-1.6,2,R457A +urn:mavedb:00000044-b-2#5063,NA,NA,p.Arg127Asn,-2.3,-2.06,1,R457N +urn:mavedb:00000044-b-2#5064,NA,NA,p.Arg127Asn,-1.82,-2.06,2,R457N +urn:mavedb:00000044-b-2#5045,NA,NA,p.Arg127Asp,-2.32,-2.34,1,R457D +urn:mavedb:00000044-b-2#5046,NA,NA,p.Arg127Asp,-2.36,-2.34,2,R457D +urn:mavedb:00000044-b-2#5043,NA,NA,p.Arg127Cys,-2.3,-2.21,1,R457C +urn:mavedb:00000044-b-2#5044,NA,NA,p.Arg127Cys,-2.13,-2.21,2,R457C +urn:mavedb:00000044-b-2#5067,NA,NA,p.Arg127Gln,-2.66,-2.55,1,R457Q +urn:mavedb:00000044-b-2#5068,NA,NA,p.Arg127Gln,-2.44,-2.55,2,R457Q +urn:mavedb:00000044-b-2#5047,NA,NA,p.Arg127Glu,-2.25,-2.26,1,R457E +urn:mavedb:00000044-b-2#5048,NA,NA,p.Arg127Glu,-2.27,-2.26,2,R457E +urn:mavedb:00000044-b-2#5051,NA,NA,p.Arg127Gly,-2.05,-1.97,1,R457G +urn:mavedb:00000044-b-2#5052,NA,NA,p.Arg127Gly,-1.89,-1.97,2,R457G +urn:mavedb:00000044-b-2#5053,NA,NA,p.Arg127His,-2.06,-1.99,1,R457H +urn:mavedb:00000044-b-2#5054,NA,NA,p.Arg127His,-1.92,-1.99,2,R457H +urn:mavedb:00000044-b-2#5055,NA,NA,p.Arg127Ile,-2.45,-2.34,1,R457I +urn:mavedb:00000044-b-2#5056,NA,NA,p.Arg127Ile,-2.23,-2.34,2,R457I +urn:mavedb:00000044-b-2#5059,NA,NA,p.Arg127Leu,-2.36,-2.34,1,R457L +urn:mavedb:00000044-b-2#5060,NA,NA,p.Arg127Leu,-2.32,-2.34,2,R457L +urn:mavedb:00000044-b-2#5057,NA,NA,p.Arg127Lys,-1.59,-1.58,1,R457K +urn:mavedb:00000044-b-2#5058,NA,NA,p.Arg127Lys,-1.57,-1.58,2,R457K +urn:mavedb:00000044-b-2#5061,NA,NA,p.Arg127Met,-2.44,-2.52,1,R457M +urn:mavedb:00000044-b-2#5062,NA,NA,p.Arg127Met,-2.6,-2.52,2,R457M +urn:mavedb:00000044-b-2#5049,NA,NA,p.Arg127Phe,-2.59,-2.54,1,R457F +urn:mavedb:00000044-b-2#5050,NA,NA,p.Arg127Phe,-2.48,-2.54,2,R457F +urn:mavedb:00000044-b-2#5065,NA,NA,p.Arg127Pro,-2.56,-2.48,1,R457P +urn:mavedb:00000044-b-2#5066,NA,NA,p.Arg127Pro,-2.4,-2.48,2,R457P +urn:mavedb:00000044-b-2#5069,NA,NA,p.Arg127Ser,-1.61,-1.68,1,R457S +urn:mavedb:00000044-b-2#5070,NA,NA,p.Arg127Ser,-1.74,-1.68,2,R457S +urn:mavedb:00000044-b-2#5071,NA,NA,p.Arg127Thr,-2.53,-2.48,1,R457T +urn:mavedb:00000044-b-2#5072,NA,NA,p.Arg127Thr,-2.42,-2.48,2,R457T +urn:mavedb:00000044-b-2#5075,NA,NA,p.Arg127Trp,-2.63,-2.54,1,R457W +urn:mavedb:00000044-b-2#5076,NA,NA,p.Arg127Trp,-2.46,-2.54,2,R457W +urn:mavedb:00000044-b-2#5077,NA,NA,p.Arg127Tyr,-2.41,-2.45,1,R457Y +urn:mavedb:00000044-b-2#5078,NA,NA,p.Arg127Tyr,-2.48,-2.45,2,R457Y +urn:mavedb:00000044-b-2#5073,NA,NA,p.Arg127Val,-2.63,-2.53,1,R457V +urn:mavedb:00000044-b-2#5074,NA,NA,p.Arg127Val,-2.43,-2.53,2,R457V +urn:mavedb:00000044-b-2#5439,NA,NA,p.Arg136*,-4.63,-4.58,1,R466 +urn:mavedb:00000044-b-2#5440,NA,NA,p.Arg136*,-4.53,-4.58,2,R466 +urn:mavedb:00000044-b-2#5401,NA,NA,p.Arg136Ala,-1.61,-1.7,1,R466A +urn:mavedb:00000044-b-2#5402,NA,NA,p.Arg136Ala,-1.79,-1.7,2,R466A +urn:mavedb:00000044-b-2#5423,NA,NA,p.Arg136Asn,-1.99,-1.89,1,R466N +urn:mavedb:00000044-b-2#5424,NA,NA,p.Arg136Asn,-1.78,-1.89,2,R466N +urn:mavedb:00000044-b-2#5405,NA,NA,p.Arg136Asp,-2.63,-2.48,1,R466D +urn:mavedb:00000044-b-2#5406,NA,NA,p.Arg136Asp,-2.33,-2.48,2,R466D +urn:mavedb:00000044-b-2#5403,NA,NA,p.Arg136Cys,-1.47,-1.41,1,R466C +urn:mavedb:00000044-b-2#5404,NA,NA,p.Arg136Cys,-1.35,-1.41,2,R466C +urn:mavedb:00000044-b-2#5427,NA,NA,p.Arg136Gln,-0.38,-0.36,1,R466Q +urn:mavedb:00000044-b-2#5428,NA,NA,p.Arg136Gln,-0.33,-0.36,2,R466Q +urn:mavedb:00000044-b-2#5407,NA,NA,p.Arg136Glu,-2.27,-2.2,1,R466E +urn:mavedb:00000044-b-2#5408,NA,NA,p.Arg136Glu,-2.13,-2.2,2,R466E +urn:mavedb:00000044-b-2#5411,NA,NA,p.Arg136Gly,-2.33,-2.34,1,R466G +urn:mavedb:00000044-b-2#5412,NA,NA,p.Arg136Gly,-2.34,-2.34,2,R466G +urn:mavedb:00000044-b-2#5413,NA,NA,p.Arg136His,-0.99,-0.97,1,R466H +urn:mavedb:00000044-b-2#5414,NA,NA,p.Arg136His,-0.95,-0.97,2,R466H +urn:mavedb:00000044-b-2#5415,NA,NA,p.Arg136Ile,-1.58,-1.44,1,R466I +urn:mavedb:00000044-b-2#5416,NA,NA,p.Arg136Ile,-1.29,-1.44,2,R466I +urn:mavedb:00000044-b-2#5419,NA,NA,p.Arg136Leu,-1.44,-1.44,1,R466L +urn:mavedb:00000044-b-2#5420,NA,NA,p.Arg136Leu,-1.44,-1.44,2,R466L +urn:mavedb:00000044-b-2#5417,NA,NA,p.Arg136Lys,-0.18,-0.22,1,R466K +urn:mavedb:00000044-b-2#5418,NA,NA,p.Arg136Lys,-0.25,-0.22,2,R466K +urn:mavedb:00000044-b-2#5421,NA,NA,p.Arg136Met,-1.22,-1.35,1,R466M +urn:mavedb:00000044-b-2#5422,NA,NA,p.Arg136Met,-1.48,-1.35,2,R466M +urn:mavedb:00000044-b-2#5409,NA,NA,p.Arg136Phe,-2.28,-2.18,1,R466F +urn:mavedb:00000044-b-2#5410,NA,NA,p.Arg136Phe,-2.08,-2.18,2,R466F +urn:mavedb:00000044-b-2#5425,NA,NA,p.Arg136Pro,-2.4,-2.42,1,R466P +urn:mavedb:00000044-b-2#5426,NA,NA,p.Arg136Pro,-2.45,-2.42,2,R466P +urn:mavedb:00000044-b-2#5429,NA,NA,p.Arg136Ser,-1.5,-1.41,1,R466S +urn:mavedb:00000044-b-2#5430,NA,NA,p.Arg136Ser,-1.33,-1.41,2,R466S +urn:mavedb:00000044-b-2#5431,NA,NA,p.Arg136Thr,-1.81,-1.75,1,R466T +urn:mavedb:00000044-b-2#5432,NA,NA,p.Arg136Thr,-1.69,-1.75,2,R466T +urn:mavedb:00000044-b-2#5435,NA,NA,p.Arg136Trp,-1.88,-1.83,1,R466W +urn:mavedb:00000044-b-2#5436,NA,NA,p.Arg136Trp,-1.79,-1.83,2,R466W +urn:mavedb:00000044-b-2#5437,NA,NA,p.Arg136Tyr,-2.12,-2.01,1,R466Y +urn:mavedb:00000044-b-2#5438,NA,NA,p.Arg136Tyr,-1.9,-2.01,2,R466Y +urn:mavedb:00000044-b-2#5433,NA,NA,p.Arg136Val,-1.73,-1.73,1,R466V +urn:mavedb:00000044-b-2#5434,NA,NA,p.Arg136Val,-1.73,-1.73,2,R466V +urn:mavedb:00000044-b-2#639,NA,NA,p.Arg16*,-4.63,-4.62,1,R346 +urn:mavedb:00000044-b-2#640,NA,NA,p.Arg16*,-4.62,-4.62,2,R346 +urn:mavedb:00000044-b-2#601,NA,NA,p.Arg16Ala,-0.33,-0.27,1,R346A +urn:mavedb:00000044-b-2#602,NA,NA,p.Arg16Ala,-0.2,-0.27,2,R346A +urn:mavedb:00000044-b-2#623,NA,NA,p.Arg16Asn,0.16,0.15,1,R346N +urn:mavedb:00000044-b-2#624,NA,NA,p.Arg16Asn,0.15,0.15,2,R346N +urn:mavedb:00000044-b-2#605,NA,NA,p.Arg16Asp,-0.08,-0.02,1,R346D +urn:mavedb:00000044-b-2#606,NA,NA,p.Arg16Asp,0.04,-0.02,2,R346D +urn:mavedb:00000044-b-2#603,NA,NA,p.Arg16Cys,-0.46,-0.45,1,R346C +urn:mavedb:00000044-b-2#604,NA,NA,p.Arg16Cys,-0.44,-0.45,2,R346C +urn:mavedb:00000044-b-2#627,NA,NA,p.Arg16Gln,0,-0.02,1,R346Q +urn:mavedb:00000044-b-2#628,NA,NA,p.Arg16Gln,-0.04,-0.02,2,R346Q +urn:mavedb:00000044-b-2#607,NA,NA,p.Arg16Glu,0.09,0.08,1,R346E +urn:mavedb:00000044-b-2#608,NA,NA,p.Arg16Glu,0.08,0.08,2,R346E +urn:mavedb:00000044-b-2#611,NA,NA,p.Arg16Gly,-0.66,-0.74,1,R346G +urn:mavedb:00000044-b-2#612,NA,NA,p.Arg16Gly,-0.83,-0.74,2,R346G +urn:mavedb:00000044-b-2#613,NA,NA,p.Arg16His,-0.09,0.03,1,R346H +urn:mavedb:00000044-b-2#614,NA,NA,p.Arg16His,0.15,0.03,2,R346H +urn:mavedb:00000044-b-2#615,NA,NA,p.Arg16Ile,-0.03,-0.03,1,R346I +urn:mavedb:00000044-b-2#616,NA,NA,p.Arg16Ile,-0.03,-0.03,2,R346I +urn:mavedb:00000044-b-2#619,NA,NA,p.Arg16Leu,-0.25,-0.36,1,R346L +urn:mavedb:00000044-b-2#620,NA,NA,p.Arg16Leu,-0.48,-0.36,2,R346L +urn:mavedb:00000044-b-2#617,NA,NA,p.Arg16Lys,0.12,0.12,1,R346K +urn:mavedb:00000044-b-2#618,NA,NA,p.Arg16Lys,0.12,0.12,2,R346K +urn:mavedb:00000044-b-2#621,NA,NA,p.Arg16Met,-0.25,-0.28,1,R346M +urn:mavedb:00000044-b-2#622,NA,NA,p.Arg16Met,-0.31,-0.28,2,R346M +urn:mavedb:00000044-b-2#609,NA,NA,p.Arg16Phe,-0.43,-0.31,1,R346F +urn:mavedb:00000044-b-2#610,NA,NA,p.Arg16Phe,-0.18,-0.31,2,R346F +urn:mavedb:00000044-b-2#625,NA,NA,p.Arg16Pro,-1.31,-1.34,1,R346P +urn:mavedb:00000044-b-2#626,NA,NA,p.Arg16Pro,-1.36,-1.34,2,R346P +urn:mavedb:00000044-b-2#629,NA,NA,p.Arg16Ser,0,0.02,1,R346S +urn:mavedb:00000044-b-2#630,NA,NA,p.Arg16Ser,0.04,0.02,2,R346S +urn:mavedb:00000044-b-2#631,NA,NA,p.Arg16Thr,0.16,0.15,1,R346T +urn:mavedb:00000044-b-2#632,NA,NA,p.Arg16Thr,0.14,0.15,2,R346T +urn:mavedb:00000044-b-2#635,NA,NA,p.Arg16Trp,-0.36,-0.45,1,R346W +urn:mavedb:00000044-b-2#636,NA,NA,p.Arg16Trp,-0.55,-0.45,2,R346W +urn:mavedb:00000044-b-2#637,NA,NA,p.Arg16Tyr,-0.16,-0.12,1,R346Y +urn:mavedb:00000044-b-2#638,NA,NA,p.Arg16Tyr,-0.08,-0.12,2,R346Y +urn:mavedb:00000044-b-2#633,NA,NA,p.Arg16Val,-0.01,0.01,1,R346V +urn:mavedb:00000044-b-2#634,NA,NA,p.Arg16Val,0.02,0.01,2,R346V +urn:mavedb:00000044-b-2#7159,NA,NA,p.Arg179*,-4.68,-4.38,1,R509 +urn:mavedb:00000044-b-2#7160,NA,NA,p.Arg179*,-4.07,-4.38,2,R509 +urn:mavedb:00000044-b-2#7121,NA,NA,p.Arg179Ala,-2.62,-2.5,1,R509A +urn:mavedb:00000044-b-2#7122,NA,NA,p.Arg179Ala,-2.39,-2.5,2,R509A +urn:mavedb:00000044-b-2#7143,NA,NA,p.Arg179Asn,-2.32,-2.23,1,R509N +urn:mavedb:00000044-b-2#7144,NA,NA,p.Arg179Asn,-2.14,-2.23,2,R509N +urn:mavedb:00000044-b-2#7125,NA,NA,p.Arg179Asp,-2.87,-2.78,1,R509D +urn:mavedb:00000044-b-2#7126,NA,NA,p.Arg179Asp,-2.69,-2.78,2,R509D +urn:mavedb:00000044-b-2#7123,NA,NA,p.Arg179Cys,-2.65,-2.31,1,R509C +urn:mavedb:00000044-b-2#7124,NA,NA,p.Arg179Cys,-1.97,-2.31,2,R509C +urn:mavedb:00000044-b-2#7147,NA,NA,p.Arg179Gln,-2.52,-2.54,1,R509Q +urn:mavedb:00000044-b-2#7148,NA,NA,p.Arg179Gln,-2.56,-2.54,2,R509Q +urn:mavedb:00000044-b-2#7127,NA,NA,p.Arg179Glu,-2.53,-2.53,1,R509E +urn:mavedb:00000044-b-2#7128,NA,NA,p.Arg179Glu,-2.54,-2.53,2,R509E +urn:mavedb:00000044-b-2#7131,NA,NA,p.Arg179Gly,-2.78,-2.66,1,R509G +urn:mavedb:00000044-b-2#7132,NA,NA,p.Arg179Gly,-2.54,-2.66,2,R509G +urn:mavedb:00000044-b-2#7133,NA,NA,p.Arg179His,-2.89,-2.51,1,R509H +urn:mavedb:00000044-b-2#7134,NA,NA,p.Arg179His,-2.12,-2.51,2,R509H +urn:mavedb:00000044-b-2#7135,NA,NA,p.Arg179Ile,-2.7,-2.67,1,R509I +urn:mavedb:00000044-b-2#7136,NA,NA,p.Arg179Ile,-2.65,-2.67,2,R509I +urn:mavedb:00000044-b-2#7139,NA,NA,p.Arg179Leu,-2.98,-2.88,1,R509L +urn:mavedb:00000044-b-2#7140,NA,NA,p.Arg179Leu,-2.78,-2.88,2,R509L +urn:mavedb:00000044-b-2#7137,NA,NA,p.Arg179Lys,-2.24,-2.05,1,R509K +urn:mavedb:00000044-b-2#7138,NA,NA,p.Arg179Lys,-1.87,-2.05,2,R509K +urn:mavedb:00000044-b-2#7141,NA,NA,p.Arg179Met,-2.4,-2.59,1,R509M +urn:mavedb:00000044-b-2#7142,NA,NA,p.Arg179Met,-2.79,-2.59,2,R509M +urn:mavedb:00000044-b-2#7129,NA,NA,p.Arg179Phe,-2.37,-2.44,1,R509F +urn:mavedb:00000044-b-2#7130,NA,NA,p.Arg179Phe,-2.51,-2.44,2,R509F +urn:mavedb:00000044-b-2#7145,NA,NA,p.Arg179Pro,-2.86,-2.8,1,R509P +urn:mavedb:00000044-b-2#7146,NA,NA,p.Arg179Pro,-2.73,-2.8,2,R509P +urn:mavedb:00000044-b-2#7149,NA,NA,p.Arg179Ser,-2.65,-2.58,1,R509S +urn:mavedb:00000044-b-2#7150,NA,NA,p.Arg179Ser,-2.51,-2.58,2,R509S +urn:mavedb:00000044-b-2#7151,NA,NA,p.Arg179Thr,-2.5,-2.45,1,R509T +urn:mavedb:00000044-b-2#7152,NA,NA,p.Arg179Thr,-2.4,-2.45,2,R509T +urn:mavedb:00000044-b-2#7155,NA,NA,p.Arg179Trp,-2.64,-2.59,1,R509W +urn:mavedb:00000044-b-2#7156,NA,NA,p.Arg179Trp,-2.53,-2.59,2,R509W +urn:mavedb:00000044-b-2#7157,NA,NA,p.Arg179Tyr,-2.03,-2.06,1,R509Y +urn:mavedb:00000044-b-2#7158,NA,NA,p.Arg179Tyr,-2.09,-2.06,2,R509Y +urn:mavedb:00000044-b-2#7153,NA,NA,p.Arg179Val,-2.5,-2.47,1,R509V +urn:mavedb:00000044-b-2#7154,NA,NA,p.Arg179Val,-2.44,-2.47,2,R509V +urn:mavedb:00000044-b-2#999,NA,NA,p.Arg25*,-4.63,-4.62,1,R355 +urn:mavedb:00000044-b-2#1000,NA,NA,p.Arg25*,-4.61,-4.62,2,R355 +urn:mavedb:00000044-b-2#961,NA,NA,p.Arg25Ala,-2.53,-2.47,1,R355A +urn:mavedb:00000044-b-2#962,NA,NA,p.Arg25Ala,-2.41,-2.47,2,R355A +urn:mavedb:00000044-b-2#983,NA,NA,p.Arg25Asn,-2.45,-2.24,1,R355N +urn:mavedb:00000044-b-2#984,NA,NA,p.Arg25Asn,-2.04,-2.24,2,R355N +urn:mavedb:00000044-b-2#965,NA,NA,p.Arg25Asp,-1.86,-1.91,1,R355D +urn:mavedb:00000044-b-2#966,NA,NA,p.Arg25Asp,-1.95,-1.91,2,R355D +urn:mavedb:00000044-b-2#963,NA,NA,p.Arg25Cys,-1.95,-1.4,1,R355C +urn:mavedb:00000044-b-2#964,NA,NA,p.Arg25Cys,-0.85,-1.4,2,R355C +urn:mavedb:00000044-b-2#987,NA,NA,p.Arg25Gln,-1.95,-2.13,1,R355Q +urn:mavedb:00000044-b-2#988,NA,NA,p.Arg25Gln,-2.3,-2.13,2,R355Q +urn:mavedb:00000044-b-2#967,NA,NA,p.Arg25Glu,-2.3,-2.13,1,R355E +urn:mavedb:00000044-b-2#968,NA,NA,p.Arg25Glu,-1.96,-2.13,2,R355E +urn:mavedb:00000044-b-2#971,NA,NA,p.Arg25Gly,-2.26,-2.24,1,R355G +urn:mavedb:00000044-b-2#972,NA,NA,p.Arg25Gly,-2.21,-2.24,2,R355G +urn:mavedb:00000044-b-2#973,NA,NA,p.Arg25His,-1.56,-1.46,1,R355H +urn:mavedb:00000044-b-2#974,NA,NA,p.Arg25His,-1.35,-1.46,2,R355H +urn:mavedb:00000044-b-2#975,NA,NA,p.Arg25Ile,-2.33,-2.53,1,R355I +urn:mavedb:00000044-b-2#976,NA,NA,p.Arg25Ile,-2.73,-2.53,2,R355I +urn:mavedb:00000044-b-2#979,NA,NA,p.Arg25Leu,-2.39,-2.45,1,R355L +urn:mavedb:00000044-b-2#980,NA,NA,p.Arg25Leu,-2.5,-2.45,2,R355L +urn:mavedb:00000044-b-2#977,NA,NA,p.Arg25Lys,-2.2,-2.21,1,R355K +urn:mavedb:00000044-b-2#978,NA,NA,p.Arg25Lys,-2.21,-2.21,2,R355K +urn:mavedb:00000044-b-2#981,NA,NA,p.Arg25Met,-2.56,-2.58,1,R355M +urn:mavedb:00000044-b-2#982,NA,NA,p.Arg25Met,-2.6,-2.58,2,R355M +urn:mavedb:00000044-b-2#969,NA,NA,p.Arg25Phe,-2.59,-2.56,1,R355F +urn:mavedb:00000044-b-2#970,NA,NA,p.Arg25Phe,-2.53,-2.56,2,R355F +urn:mavedb:00000044-b-2#985,NA,NA,p.Arg25Pro,-2.21,-2.17,1,R355P +urn:mavedb:00000044-b-2#986,NA,NA,p.Arg25Pro,-2.12,-2.17,2,R355P +urn:mavedb:00000044-b-2#989,NA,NA,p.Arg25Ser,-1.99,-1.92,1,R355S +urn:mavedb:00000044-b-2#990,NA,NA,p.Arg25Ser,-1.85,-1.92,2,R355S +urn:mavedb:00000044-b-2#991,NA,NA,p.Arg25Thr,-1.85,-1.8,1,R355T +urn:mavedb:00000044-b-2#992,NA,NA,p.Arg25Thr,-1.76,-1.8,2,R355T +urn:mavedb:00000044-b-2#995,NA,NA,p.Arg25Trp,-2.36,-2.45,1,R355W +urn:mavedb:00000044-b-2#996,NA,NA,p.Arg25Trp,-2.53,-2.45,2,R355W +urn:mavedb:00000044-b-2#997,NA,NA,p.Arg25Tyr,-2.87,-2.62,1,R355Y +urn:mavedb:00000044-b-2#998,NA,NA,p.Arg25Tyr,-2.37,-2.62,2,R355Y +urn:mavedb:00000044-b-2#993,NA,NA,p.Arg25Val,-2.42,-2.34,1,R355V +urn:mavedb:00000044-b-2#994,NA,NA,p.Arg25Val,-2.27,-2.34,2,R355V +urn:mavedb:00000044-b-2#1079,NA,NA,p.Arg27*,-4.62,-4.6,1,R357 +urn:mavedb:00000044-b-2#1080,NA,NA,p.Arg27*,-4.57,-4.6,2,R357 +urn:mavedb:00000044-b-2#1041,NA,NA,p.Arg27Ala,-0.21,-0.16,1,R357A +urn:mavedb:00000044-b-2#1042,NA,NA,p.Arg27Ala,-0.12,-0.16,2,R357A +urn:mavedb:00000044-b-2#1063,NA,NA,p.Arg27Asn,0.23,0.04,1,R357N +urn:mavedb:00000044-b-2#1064,NA,NA,p.Arg27Asn,-0.15,0.04,2,R357N +urn:mavedb:00000044-b-2#1045,NA,NA,p.Arg27Asp,-0.64,-0.47,1,R357D +urn:mavedb:00000044-b-2#1046,NA,NA,p.Arg27Asp,-0.3,-0.47,2,R357D +urn:mavedb:00000044-b-2#1043,NA,NA,p.Arg27Cys,-0.77,-0.48,1,R357C +urn:mavedb:00000044-b-2#1044,NA,NA,p.Arg27Cys,-0.2,-0.48,2,R357C +urn:mavedb:00000044-b-2#1067,NA,NA,p.Arg27Gln,0.01,0.01,1,R357Q +urn:mavedb:00000044-b-2#1068,NA,NA,p.Arg27Gln,0.01,0.01,2,R357Q +urn:mavedb:00000044-b-2#1047,NA,NA,p.Arg27Glu,-0.05,-0.02,1,R357E +urn:mavedb:00000044-b-2#1048,NA,NA,p.Arg27Glu,0.01,-0.02,2,R357E +urn:mavedb:00000044-b-2#1051,NA,NA,p.Arg27Gly,-1.21,-1.17,1,R357G +urn:mavedb:00000044-b-2#1052,NA,NA,p.Arg27Gly,-1.13,-1.17,2,R357G +urn:mavedb:00000044-b-2#1053,NA,NA,p.Arg27His,-0.09,0.04,1,R357H +urn:mavedb:00000044-b-2#1054,NA,NA,p.Arg27His,0.17,0.04,2,R357H +urn:mavedb:00000044-b-2#1055,NA,NA,p.Arg27Ile,0.07,0.03,1,R357I +urn:mavedb:00000044-b-2#1056,NA,NA,p.Arg27Ile,0,0.03,2,R357I +urn:mavedb:00000044-b-2#1059,NA,NA,p.Arg27Leu,-0.37,-0.33,1,R357L +urn:mavedb:00000044-b-2#1060,NA,NA,p.Arg27Leu,-0.28,-0.33,2,R357L +urn:mavedb:00000044-b-2#1057,NA,NA,p.Arg27Lys,0.19,0.18,1,R357K +urn:mavedb:00000044-b-2#1058,NA,NA,p.Arg27Lys,0.18,0.18,2,R357K +urn:mavedb:00000044-b-2#1061,NA,NA,p.Arg27Met,-0.43,-0.52,1,R357M +urn:mavedb:00000044-b-2#1062,NA,NA,p.Arg27Met,-0.61,-0.52,2,R357M +urn:mavedb:00000044-b-2#1049,NA,NA,p.Arg27Phe,-1.54,-1.06,1,R357F +urn:mavedb:00000044-b-2#1050,NA,NA,p.Arg27Phe,-0.57,-1.06,2,R357F +urn:mavedb:00000044-b-2#1065,NA,NA,p.Arg27Pro,-0.56,-0.63,1,R357P +urn:mavedb:00000044-b-2#1066,NA,NA,p.Arg27Pro,-0.71,-0.63,2,R357P +urn:mavedb:00000044-b-2#1069,NA,NA,p.Arg27Ser,-0.36,-0.25,1,R357S +urn:mavedb:00000044-b-2#1070,NA,NA,p.Arg27Ser,-0.15,-0.25,2,R357S +urn:mavedb:00000044-b-2#1071,NA,NA,p.Arg27Thr,-0.08,-0.02,1,R357T +urn:mavedb:00000044-b-2#1072,NA,NA,p.Arg27Thr,0.04,-0.02,2,R357T +urn:mavedb:00000044-b-2#1075,NA,NA,p.Arg27Trp,-0.88,-0.82,1,R357W +urn:mavedb:00000044-b-2#1076,NA,NA,p.Arg27Trp,-0.75,-0.82,2,R357W +urn:mavedb:00000044-b-2#1077,NA,NA,p.Arg27Tyr,-0.27,-0.42,1,R357Y +urn:mavedb:00000044-b-2#1078,NA,NA,p.Arg27Tyr,-0.57,-0.42,2,R357Y +urn:mavedb:00000044-b-2#1073,NA,NA,p.Arg27Val,0.05,0.01,1,R357V +urn:mavedb:00000044-b-2#1074,NA,NA,p.Arg27Val,-0.02,0.01,2,R357V +urn:mavedb:00000044-b-2#2919,NA,NA,p.Arg73*,-4.59,-4.55,1,R403 +urn:mavedb:00000044-b-2#2920,NA,NA,p.Arg73*,-4.51,-4.55,2,R403 +urn:mavedb:00000044-b-2#2881,NA,NA,p.Arg73Ala,-0.22,-0.22,1,R403A +urn:mavedb:00000044-b-2#2882,NA,NA,p.Arg73Ala,-0.21,-0.22,2,R403A +urn:mavedb:00000044-b-2#2903,NA,NA,p.Arg73Asn,-0.58,-0.44,1,R403N +urn:mavedb:00000044-b-2#2904,NA,NA,p.Arg73Asn,-0.3,-0.44,2,R403N +urn:mavedb:00000044-b-2#2885,NA,NA,p.Arg73Asp,-1.85,-2.3,1,R403D +urn:mavedb:00000044-b-2#2886,NA,NA,p.Arg73Asp,-2.75,-2.3,2,R403D +urn:mavedb:00000044-b-2#2883,NA,NA,p.Arg73Cys,-1.88,-1.69,1,R403C +urn:mavedb:00000044-b-2#2884,NA,NA,p.Arg73Cys,-1.5,-1.69,2,R403C +urn:mavedb:00000044-b-2#2907,NA,NA,p.Arg73Gln,-0.75,-0.8,1,R403Q +urn:mavedb:00000044-b-2#2908,NA,NA,p.Arg73Gln,-0.86,-0.8,2,R403Q +urn:mavedb:00000044-b-2#2887,NA,NA,p.Arg73Glu,-1.41,-1.31,1,R403E +urn:mavedb:00000044-b-2#2888,NA,NA,p.Arg73Glu,-1.22,-1.31,2,R403E +urn:mavedb:00000044-b-2#2891,NA,NA,p.Arg73Gly,-1.17,-1.14,1,R403G +urn:mavedb:00000044-b-2#2892,NA,NA,p.Arg73Gly,-1.11,-1.14,2,R403G +urn:mavedb:00000044-b-2#2893,NA,NA,p.Arg73His,-1.86,-1.8,1,R403H +urn:mavedb:00000044-b-2#2894,NA,NA,p.Arg73His,-1.75,-1.8,2,R403H +urn:mavedb:00000044-b-2#2895,NA,NA,p.Arg73Ile,-1.82,-1.84,1,R403I +urn:mavedb:00000044-b-2#2896,NA,NA,p.Arg73Ile,-1.87,-1.84,2,R403I +urn:mavedb:00000044-b-2#2899,NA,NA,p.Arg73Leu,-1.43,-1.63,1,R403L +urn:mavedb:00000044-b-2#2900,NA,NA,p.Arg73Leu,-1.83,-1.63,2,R403L +urn:mavedb:00000044-b-2#2897,NA,NA,p.Arg73Lys,-0.29,-0.29,1,R403K +urn:mavedb:00000044-b-2#2898,NA,NA,p.Arg73Lys,-0.28,-0.29,2,R403K +urn:mavedb:00000044-b-2#2901,NA,NA,p.Arg73Met,-0.42,-0.51,1,R403M +urn:mavedb:00000044-b-2#2902,NA,NA,p.Arg73Met,-0.6,-0.51,2,R403M +urn:mavedb:00000044-b-2#2889,NA,NA,p.Arg73Phe,-1.6,-1.61,1,R403F +urn:mavedb:00000044-b-2#2890,NA,NA,p.Arg73Phe,-1.63,-1.61,2,R403F +urn:mavedb:00000044-b-2#2905,NA,NA,p.Arg73Pro,-1.53,-1.44,1,R403P +urn:mavedb:00000044-b-2#2906,NA,NA,p.Arg73Pro,-1.36,-1.44,2,R403P +urn:mavedb:00000044-b-2#2909,NA,NA,p.Arg73Ser,-0.2,-0.22,1,R403S +urn:mavedb:00000044-b-2#2910,NA,NA,p.Arg73Ser,-0.23,-0.22,2,R403S +urn:mavedb:00000044-b-2#2911,NA,NA,p.Arg73Thr,-1.13,-0.99,1,R403T +urn:mavedb:00000044-b-2#2912,NA,NA,p.Arg73Thr,-0.86,-0.99,2,R403T +urn:mavedb:00000044-b-2#2915,NA,NA,p.Arg73Trp,-2.14,-2.06,1,R403W +urn:mavedb:00000044-b-2#2916,NA,NA,p.Arg73Trp,-1.99,-2.06,2,R403W +urn:mavedb:00000044-b-2#2917,NA,NA,p.Arg73Tyr,-1.52,-1.55,1,R403Y +urn:mavedb:00000044-b-2#2918,NA,NA,p.Arg73Tyr,-1.57,-1.55,2,R403Y +urn:mavedb:00000044-b-2#2913,NA,NA,p.Arg73Val,-2.36,-2.24,1,R403V +urn:mavedb:00000044-b-2#2914,NA,NA,p.Arg73Val,-2.13,-2.24,2,R403V +urn:mavedb:00000044-b-2#3119,NA,NA,p.Arg78*,-3.56,-3.49,1,R408 +urn:mavedb:00000044-b-2#3120,NA,NA,p.Arg78*,-3.42,-3.49,2,R408 +urn:mavedb:00000044-b-2#3081,NA,NA,p.Arg78Ala,0.15,0.12,1,R408A +urn:mavedb:00000044-b-2#3082,NA,NA,p.Arg78Ala,0.08,0.12,2,R408A +urn:mavedb:00000044-b-2#3103,NA,NA,p.Arg78Asn,0,-0.13,1,R408N +urn:mavedb:00000044-b-2#3104,NA,NA,p.Arg78Asn,-0.27,-0.13,2,R408N +urn:mavedb:00000044-b-2#3085,NA,NA,p.Arg78Asp,NA,0.53,1,R408D +urn:mavedb:00000044-b-2#3086,NA,NA,p.Arg78Asp,0.53,0.53,2,R408D +urn:mavedb:00000044-b-2#3083,NA,NA,p.Arg78Cys,0,-0.06,1,R408C +urn:mavedb:00000044-b-2#3084,NA,NA,p.Arg78Cys,-0.11,-0.06,2,R408C +urn:mavedb:00000044-b-2#3107,NA,NA,p.Arg78Gln,0.23,0.29,1,R408Q +urn:mavedb:00000044-b-2#3108,NA,NA,p.Arg78Gln,0.36,0.29,2,R408Q +urn:mavedb:00000044-b-2#3087,NA,NA,p.Arg78Glu,0.29,0.27,1,R408E +urn:mavedb:00000044-b-2#3088,NA,NA,p.Arg78Glu,0.24,0.27,2,R408E +urn:mavedb:00000044-b-2#3091,NA,NA,p.Arg78Gly,0.01,0.09,1,R408G +urn:mavedb:00000044-b-2#3092,NA,NA,p.Arg78Gly,0.17,0.09,2,R408G +urn:mavedb:00000044-b-2#3093,NA,NA,p.Arg78His,-0.01,0.02,1,R408H +urn:mavedb:00000044-b-2#3094,NA,NA,p.Arg78His,0.05,0.02,2,R408H +urn:mavedb:00000044-b-2#3095,NA,NA,p.Arg78Ile,-0.68,-0.46,1,R408I +urn:mavedb:00000044-b-2#3096,NA,NA,p.Arg78Ile,-0.24,-0.46,2,R408I +urn:mavedb:00000044-b-2#3099,NA,NA,p.Arg78Leu,-0.45,-0.54,1,R408L +urn:mavedb:00000044-b-2#3100,NA,NA,p.Arg78Leu,-0.63,-0.54,2,R408L +urn:mavedb:00000044-b-2#3097,NA,NA,p.Arg78Lys,0.04,0.06,1,R408K +urn:mavedb:00000044-b-2#3098,NA,NA,p.Arg78Lys,0.08,0.06,2,R408K +urn:mavedb:00000044-b-2#3101,NA,NA,p.Arg78Met,-0.65,-0.48,1,R408M +urn:mavedb:00000044-b-2#3102,NA,NA,p.Arg78Met,-0.3,-0.48,2,R408M +urn:mavedb:00000044-b-2#3089,NA,NA,p.Arg78Phe,-0.67,-0.48,1,R408F +urn:mavedb:00000044-b-2#3090,NA,NA,p.Arg78Phe,-0.28,-0.48,2,R408F +urn:mavedb:00000044-b-2#3105,NA,NA,p.Arg78Pro,0.1,0.15,1,R408P +urn:mavedb:00000044-b-2#3106,NA,NA,p.Arg78Pro,0.19,0.15,2,R408P +urn:mavedb:00000044-b-2#3109,NA,NA,p.Arg78Ser,0.33,0.21,1,R408S +urn:mavedb:00000044-b-2#3110,NA,NA,p.Arg78Ser,0.1,0.21,2,R408S +urn:mavedb:00000044-b-2#3111,NA,NA,p.Arg78Thr,-0.11,-0.06,1,R408T +urn:mavedb:00000044-b-2#3112,NA,NA,p.Arg78Thr,-0.02,-0.06,2,R408T +urn:mavedb:00000044-b-2#3115,NA,NA,p.Arg78Trp,-0.47,-0.56,1,R408W +urn:mavedb:00000044-b-2#3116,NA,NA,p.Arg78Trp,-0.65,-0.56,2,R408W +urn:mavedb:00000044-b-2#3117,NA,NA,p.Arg78Tyr,-0.05,-0.22,1,R408Y +urn:mavedb:00000044-b-2#3118,NA,NA,p.Arg78Tyr,-0.39,-0.22,2,R408Y +urn:mavedb:00000044-b-2#3113,NA,NA,p.Arg78Val,-0.01,0.04,1,R408V +urn:mavedb:00000044-b-2#3114,NA,NA,p.Arg78Val,0.08,0.04,2,R408V +urn:mavedb:00000044-b-2#39,NA,NA,p.Asn1*,-4.66,-4.63,1,N331 +urn:mavedb:00000044-b-2#40,NA,NA,p.Asn1*,-4.6,-4.63,2,N331 +urn:mavedb:00000044-b-2#4279,NA,NA,p.Asn107*,-4.6,-4.56,1,N437 +urn:mavedb:00000044-b-2#4280,NA,NA,p.Asn107*,-4.52,-4.56,2,N437 +urn:mavedb:00000044-b-2#4241,NA,NA,p.Asn107Ala,-1.52,-1.41,1,N437A +urn:mavedb:00000044-b-2#4242,NA,NA,p.Asn107Ala,-1.31,-1.41,2,N437A +urn:mavedb:00000044-b-2#4267,NA,NA,p.Asn107Arg,-1.48,-1.53,1,N437R +urn:mavedb:00000044-b-2#4268,NA,NA,p.Asn107Arg,-1.59,-1.53,2,N437R +urn:mavedb:00000044-b-2#4245,NA,NA,p.Asn107Asp,-1.85,-1.71,1,N437D +urn:mavedb:00000044-b-2#4246,NA,NA,p.Asn107Asp,-1.57,-1.71,2,N437D +urn:mavedb:00000044-b-2#4243,NA,NA,p.Asn107Cys,-1.22,-1.13,1,N437C +urn:mavedb:00000044-b-2#4244,NA,NA,p.Asn107Cys,-1.04,-1.13,2,N437C +urn:mavedb:00000044-b-2#4265,NA,NA,p.Asn107Gln,-1.48,-1.5,1,N437Q +urn:mavedb:00000044-b-2#4266,NA,NA,p.Asn107Gln,-1.52,-1.5,2,N437Q +urn:mavedb:00000044-b-2#4247,NA,NA,p.Asn107Glu,-1.15,-1.18,1,N437E +urn:mavedb:00000044-b-2#4248,NA,NA,p.Asn107Glu,-1.21,-1.18,2,N437E +urn:mavedb:00000044-b-2#4251,NA,NA,p.Asn107Gly,-1.65,-1.65,1,N437G +urn:mavedb:00000044-b-2#4252,NA,NA,p.Asn107Gly,-1.66,-1.65,2,N437G +urn:mavedb:00000044-b-2#4253,NA,NA,p.Asn107His,-2.09,-2.08,1,N437H +urn:mavedb:00000044-b-2#4254,NA,NA,p.Asn107His,-2.08,-2.08,2,N437H +urn:mavedb:00000044-b-2#4255,NA,NA,p.Asn107Ile,-2.29,-2.23,1,N437I +urn:mavedb:00000044-b-2#4256,NA,NA,p.Asn107Ile,-2.17,-2.23,2,N437I +urn:mavedb:00000044-b-2#4259,NA,NA,p.Asn107Leu,-2.01,-2.04,1,N437L +urn:mavedb:00000044-b-2#4260,NA,NA,p.Asn107Leu,-2.06,-2.04,2,N437L +urn:mavedb:00000044-b-2#4257,NA,NA,p.Asn107Lys,-1.36,-1.31,1,N437K +urn:mavedb:00000044-b-2#4258,NA,NA,p.Asn107Lys,-1.26,-1.31,2,N437K +urn:mavedb:00000044-b-2#4261,NA,NA,p.Asn107Met,-2.07,-2.02,1,N437M +urn:mavedb:00000044-b-2#4262,NA,NA,p.Asn107Met,-1.97,-2.02,2,N437M +urn:mavedb:00000044-b-2#4249,NA,NA,p.Asn107Phe,-2.51,-2.45,1,N437F +urn:mavedb:00000044-b-2#4250,NA,NA,p.Asn107Phe,-2.38,-2.45,2,N437F +urn:mavedb:00000044-b-2#4263,NA,NA,p.Asn107Pro,-0.82,-0.8,1,N437P +urn:mavedb:00000044-b-2#4264,NA,NA,p.Asn107Pro,-0.77,-0.8,2,N437P +urn:mavedb:00000044-b-2#4269,NA,NA,p.Asn107Ser,-1.49,-1.57,1,N437S +urn:mavedb:00000044-b-2#4270,NA,NA,p.Asn107Ser,-1.66,-1.57,2,N437S +urn:mavedb:00000044-b-2#4271,NA,NA,p.Asn107Thr,-2.13,-2.11,1,N437T +urn:mavedb:00000044-b-2#4272,NA,NA,p.Asn107Thr,-2.08,-2.11,2,N437T +urn:mavedb:00000044-b-2#4275,NA,NA,p.Asn107Trp,-2.24,-2.24,1,N437W +urn:mavedb:00000044-b-2#4276,NA,NA,p.Asn107Trp,-2.23,-2.24,2,N437W +urn:mavedb:00000044-b-2#4277,NA,NA,p.Asn107Tyr,-2.36,-2.34,1,N437Y +urn:mavedb:00000044-b-2#4278,NA,NA,p.Asn107Tyr,-2.31,-2.34,2,N437Y +urn:mavedb:00000044-b-2#4273,NA,NA,p.Asn107Val,-2.16,-2.08,1,N437V +urn:mavedb:00000044-b-2#4274,NA,NA,p.Asn107Val,-2.01,-2.08,2,N437V +urn:mavedb:00000044-b-2#4359,NA,NA,p.Asn109*,-3.07,-3.24,1,N439 +urn:mavedb:00000044-b-2#4360,NA,NA,p.Asn109*,-3.41,-3.24,2,N439 +urn:mavedb:00000044-b-2#4321,NA,NA,p.Asn109Ala,-2.88,-1.54,1,N439A +urn:mavedb:00000044-b-2#4322,NA,NA,p.Asn109Ala,-0.2,-1.54,2,N439A +urn:mavedb:00000044-b-2#4347,NA,NA,p.Asn109Arg,-1.33,-1.06,1,N439R +urn:mavedb:00000044-b-2#4348,NA,NA,p.Asn109Arg,-0.79,-1.06,2,N439R +urn:mavedb:00000044-b-2#4325,NA,NA,p.Asn109Asp,-0.62,-0.8,1,N439D +urn:mavedb:00000044-b-2#4326,NA,NA,p.Asn109Asp,-0.97,-0.8,2,N439D +urn:mavedb:00000044-b-2#4323,NA,NA,p.Asn109Cys,-0.34,-0.28,1,N439C +urn:mavedb:00000044-b-2#4324,NA,NA,p.Asn109Cys,-0.23,-0.28,2,N439C +urn:mavedb:00000044-b-2#4345,NA,NA,p.Asn109Gln,0.04,-0.02,1,N439Q +urn:mavedb:00000044-b-2#4346,NA,NA,p.Asn109Gln,-0.08,-0.02,2,N439Q +urn:mavedb:00000044-b-2#4327,NA,NA,p.Asn109Glu,-0.26,-0.61,1,N439E +urn:mavedb:00000044-b-2#4328,NA,NA,p.Asn109Glu,-0.95,-0.61,2,N439E +urn:mavedb:00000044-b-2#4331,NA,NA,p.Asn109Gly,-1.19,-0.8,1,N439G +urn:mavedb:00000044-b-2#4332,NA,NA,p.Asn109Gly,-0.41,-0.8,2,N439G +urn:mavedb:00000044-b-2#4333,NA,NA,p.Asn109His,-0.22,-0.36,1,N439H +urn:mavedb:00000044-b-2#4334,NA,NA,p.Asn109His,-0.5,-0.36,2,N439H +urn:mavedb:00000044-b-2#4335,NA,NA,p.Asn109Ile,-1.09,-1.22,1,N439I +urn:mavedb:00000044-b-2#4336,NA,NA,p.Asn109Ile,-1.34,-1.22,2,N439I +urn:mavedb:00000044-b-2#4339,NA,NA,p.Asn109Leu,-1.05,-0.73,1,N439L +urn:mavedb:00000044-b-2#4340,NA,NA,p.Asn109Leu,-0.42,-0.73,2,N439L +urn:mavedb:00000044-b-2#4337,NA,NA,p.Asn109Lys,-0.33,-0.35,1,N439K +urn:mavedb:00000044-b-2#4338,NA,NA,p.Asn109Lys,-0.36,-0.35,2,N439K +urn:mavedb:00000044-b-2#4341,NA,NA,p.Asn109Met,-0.27,-0.23,1,N439M +urn:mavedb:00000044-b-2#4342,NA,NA,p.Asn109Met,-0.2,-0.23,2,N439M +urn:mavedb:00000044-b-2#4329,NA,NA,p.Asn109Phe,-3.04,-2.08,1,N439F +urn:mavedb:00000044-b-2#4330,NA,NA,p.Asn109Phe,-1.12,-2.08,2,N439F +urn:mavedb:00000044-b-2#4343,NA,NA,p.Asn109Pro,-1.92,-0.82,1,N439P +urn:mavedb:00000044-b-2#4344,NA,NA,p.Asn109Pro,0.28,-0.82,2,N439P +urn:mavedb:00000044-b-2#4349,NA,NA,p.Asn109Ser,-0.4,-0.39,1,N439S +urn:mavedb:00000044-b-2#4350,NA,NA,p.Asn109Ser,-0.37,-0.39,2,N439S +urn:mavedb:00000044-b-2#4351,NA,NA,p.Asn109Thr,-0.47,-0.4,1,N439T +urn:mavedb:00000044-b-2#4352,NA,NA,p.Asn109Thr,-0.34,-0.4,2,N439T +urn:mavedb:00000044-b-2#4355,NA,NA,p.Asn109Trp,-1.62,-1.57,1,N439W +urn:mavedb:00000044-b-2#4356,NA,NA,p.Asn109Trp,-1.53,-1.57,2,N439W +urn:mavedb:00000044-b-2#4357,NA,NA,p.Asn109Tyr,-0.49,-0.36,1,N439Y +urn:mavedb:00000044-b-2#4358,NA,NA,p.Asn109Tyr,-0.23,-0.36,2,N439Y +urn:mavedb:00000044-b-2#4353,NA,NA,p.Asn109Val,-0.41,-0.44,1,N439V +urn:mavedb:00000044-b-2#4354,NA,NA,p.Asn109Val,-0.47,-0.44,2,N439V +urn:mavedb:00000044-b-2#4399,NA,NA,p.Asn110*,-4.58,-4.55,1,N440 +urn:mavedb:00000044-b-2#4400,NA,NA,p.Asn110*,-4.51,-4.55,2,N440 +urn:mavedb:00000044-b-2#4361,NA,NA,p.Asn110Ala,0.09,-0.01,1,N440A +urn:mavedb:00000044-b-2#4362,NA,NA,p.Asn110Ala,-0.11,-0.01,2,N440A +urn:mavedb:00000044-b-2#4387,NA,NA,p.Asn110Arg,-0.31,-0.25,1,N440R +urn:mavedb:00000044-b-2#4388,NA,NA,p.Asn110Arg,-0.2,-0.25,2,N440R +urn:mavedb:00000044-b-2#4365,NA,NA,p.Asn110Asp,0.31,0.07,1,N440D +urn:mavedb:00000044-b-2#4366,NA,NA,p.Asn110Asp,-0.16,0.07,2,N440D +urn:mavedb:00000044-b-2#4363,NA,NA,p.Asn110Cys,-0.9,-0.57,1,N440C +urn:mavedb:00000044-b-2#4364,NA,NA,p.Asn110Cys,-0.24,-0.57,2,N440C +urn:mavedb:00000044-b-2#4385,NA,NA,p.Asn110Gln,-0.2,-0.2,1,N440Q +urn:mavedb:00000044-b-2#4386,NA,NA,p.Asn110Gln,-0.2,-0.2,2,N440Q +urn:mavedb:00000044-b-2#4367,NA,NA,p.Asn110Glu,0.17,0.23,1,N440E +urn:mavedb:00000044-b-2#4368,NA,NA,p.Asn110Glu,0.29,0.23,2,N440E +urn:mavedb:00000044-b-2#4371,NA,NA,p.Asn110Gly,0.11,-0.05,1,N440G +urn:mavedb:00000044-b-2#4372,NA,NA,p.Asn110Gly,-0.22,-0.05,2,N440G +urn:mavedb:00000044-b-2#4373,NA,NA,p.Asn110His,0.03,-0.07,1,N440H +urn:mavedb:00000044-b-2#4374,NA,NA,p.Asn110His,-0.17,-0.07,2,N440H +urn:mavedb:00000044-b-2#4375,NA,NA,p.Asn110Ile,-0.24,-0.24,1,N440I +urn:mavedb:00000044-b-2#4376,NA,NA,p.Asn110Ile,-0.24,-0.24,2,N440I +urn:mavedb:00000044-b-2#4379,NA,NA,p.Asn110Leu,-0.11,-0.13,1,N440L +urn:mavedb:00000044-b-2#4380,NA,NA,p.Asn110Leu,-0.16,-0.13,2,N440L +urn:mavedb:00000044-b-2#4377,NA,NA,p.Asn110Lys,0.07,-0.12,1,N440K +urn:mavedb:00000044-b-2#4378,NA,NA,p.Asn110Lys,-0.31,-0.12,2,N440K +urn:mavedb:00000044-b-2#4381,NA,NA,p.Asn110Met,-0.16,-0.24,1,N440M +urn:mavedb:00000044-b-2#4382,NA,NA,p.Asn110Met,-0.33,-0.24,2,N440M +urn:mavedb:00000044-b-2#4369,NA,NA,p.Asn110Phe,-1.03,-0.71,1,N440F +urn:mavedb:00000044-b-2#4370,NA,NA,p.Asn110Phe,-0.39,-0.71,2,N440F +urn:mavedb:00000044-b-2#4383,NA,NA,p.Asn110Pro,-0.71,-0.62,1,N440P +urn:mavedb:00000044-b-2#4384,NA,NA,p.Asn110Pro,-0.53,-0.62,2,N440P +urn:mavedb:00000044-b-2#4389,NA,NA,p.Asn110Ser,-0.06,-0.07,1,N440S +urn:mavedb:00000044-b-2#4390,NA,NA,p.Asn110Ser,-0.08,-0.07,2,N440S +urn:mavedb:00000044-b-2#4391,NA,NA,p.Asn110Thr,-0.14,-0.1,1,N440T +urn:mavedb:00000044-b-2#4392,NA,NA,p.Asn110Thr,-0.06,-0.1,2,N440T +urn:mavedb:00000044-b-2#4395,NA,NA,p.Asn110Trp,-1.42,-1.08,1,N440W +urn:mavedb:00000044-b-2#4396,NA,NA,p.Asn110Trp,-0.75,-1.08,2,N440W +urn:mavedb:00000044-b-2#4397,NA,NA,p.Asn110Tyr,-0.41,-0.36,1,N440Y +urn:mavedb:00000044-b-2#4398,NA,NA,p.Asn110Tyr,-0.31,-0.36,2,N440Y +urn:mavedb:00000044-b-2#4393,NA,NA,p.Asn110Val,-0.39,-0.4,1,N440V +urn:mavedb:00000044-b-2#4394,NA,NA,p.Asn110Val,-0.41,-0.4,2,N440V +urn:mavedb:00000044-b-2#4719,NA,NA,p.Asn118*,-4.59,-4.55,1,N448 +urn:mavedb:00000044-b-2#4720,NA,NA,p.Asn118*,-4.51,-4.55,2,N448 +urn:mavedb:00000044-b-2#4681,NA,NA,p.Asn118Ala,-1.07,-0.66,1,N448A +urn:mavedb:00000044-b-2#4682,NA,NA,p.Asn118Ala,-0.25,-0.66,2,N448A +urn:mavedb:00000044-b-2#4707,NA,NA,p.Asn118Arg,-0.37,-0.59,1,N448R +urn:mavedb:00000044-b-2#4708,NA,NA,p.Asn118Arg,-0.82,-0.59,2,N448R +urn:mavedb:00000044-b-2#4685,NA,NA,p.Asn118Asp,-0.35,-0.28,1,N448D +urn:mavedb:00000044-b-2#4686,NA,NA,p.Asn118Asp,-0.2,-0.28,2,N448D +urn:mavedb:00000044-b-2#4683,NA,NA,p.Asn118Cys,-1.07,-0.88,1,N448C +urn:mavedb:00000044-b-2#4684,NA,NA,p.Asn118Cys,-0.68,-0.88,2,N448C +urn:mavedb:00000044-b-2#4705,NA,NA,p.Asn118Gln,-0.32,-0.32,1,N448Q +urn:mavedb:00000044-b-2#4706,NA,NA,p.Asn118Gln,-0.32,-0.32,2,N448Q +urn:mavedb:00000044-b-2#4687,NA,NA,p.Asn118Glu,-0.16,-0.1,1,N448E +urn:mavedb:00000044-b-2#4688,NA,NA,p.Asn118Glu,-0.05,-0.1,2,N448E +urn:mavedb:00000044-b-2#4691,NA,NA,p.Asn118Gly,-0.1,-0.11,1,N448G +urn:mavedb:00000044-b-2#4692,NA,NA,p.Asn118Gly,-0.12,-0.11,2,N448G +urn:mavedb:00000044-b-2#4693,NA,NA,p.Asn118His,-0.29,-0.41,1,N448H +urn:mavedb:00000044-b-2#4694,NA,NA,p.Asn118His,-0.53,-0.41,2,N448H +urn:mavedb:00000044-b-2#4695,NA,NA,p.Asn118Ile,-1.74,-1.68,1,N448I +urn:mavedb:00000044-b-2#4696,NA,NA,p.Asn118Ile,-1.62,-1.68,2,N448I +urn:mavedb:00000044-b-2#4699,NA,NA,p.Asn118Leu,-1.67,-1.54,1,N448L +urn:mavedb:00000044-b-2#4700,NA,NA,p.Asn118Leu,-1.41,-1.54,2,N448L +urn:mavedb:00000044-b-2#4697,NA,NA,p.Asn118Lys,-0.59,-0.68,1,N448K +urn:mavedb:00000044-b-2#4698,NA,NA,p.Asn118Lys,-0.77,-0.68,2,N448K +urn:mavedb:00000044-b-2#4701,NA,NA,p.Asn118Met,-1.03,-0.8,1,N448M +urn:mavedb:00000044-b-2#4702,NA,NA,p.Asn118Met,-0.58,-0.8,2,N448M +urn:mavedb:00000044-b-2#4689,NA,NA,p.Asn118Phe,-1.08,-1.26,1,N448F +urn:mavedb:00000044-b-2#4690,NA,NA,p.Asn118Phe,-1.44,-1.26,2,N448F +urn:mavedb:00000044-b-2#4703,NA,NA,p.Asn118Pro,-0.51,-0.64,1,N448P +urn:mavedb:00000044-b-2#4704,NA,NA,p.Asn118Pro,-0.76,-0.64,2,N448P +urn:mavedb:00000044-b-2#4709,NA,NA,p.Asn118Ser,-0.16,-0.16,1,N448S +urn:mavedb:00000044-b-2#4710,NA,NA,p.Asn118Ser,-0.17,-0.16,2,N448S +urn:mavedb:00000044-b-2#4711,NA,NA,p.Asn118Thr,-0.26,-0.25,1,N448T +urn:mavedb:00000044-b-2#4712,NA,NA,p.Asn118Thr,-0.24,-0.25,2,N448T +urn:mavedb:00000044-b-2#4715,NA,NA,p.Asn118Trp,-1.46,-1.55,1,N448W +urn:mavedb:00000044-b-2#4716,NA,NA,p.Asn118Trp,-1.64,-1.55,2,N448W +urn:mavedb:00000044-b-2#4717,NA,NA,p.Asn118Tyr,-0.82,-0.88,1,N448Y +urn:mavedb:00000044-b-2#4718,NA,NA,p.Asn118Tyr,-0.94,-0.88,2,N448Y +urn:mavedb:00000044-b-2#4713,NA,NA,p.Asn118Val,-0.79,-0.78,1,N448V +urn:mavedb:00000044-b-2#4714,NA,NA,p.Asn118Val,-0.77,-0.78,2,N448V +urn:mavedb:00000044-b-2#4799,NA,NA,p.Asn120*,-4.53,-4.52,1,N450 +urn:mavedb:00000044-b-2#4800,NA,NA,p.Asn120*,-4.52,-4.52,2,N450 +urn:mavedb:00000044-b-2#4761,NA,NA,p.Asn120Ala,-0.2,-0.11,1,N450A +urn:mavedb:00000044-b-2#4762,NA,NA,p.Asn120Ala,-0.03,-0.11,2,N450A +urn:mavedb:00000044-b-2#4787,NA,NA,p.Asn120Arg,-0.09,-0.13,1,N450R +urn:mavedb:00000044-b-2#4788,NA,NA,p.Asn120Arg,-0.18,-0.13,2,N450R +urn:mavedb:00000044-b-2#4765,NA,NA,p.Asn120Asp,0.1,0.04,1,N450D +urn:mavedb:00000044-b-2#4766,NA,NA,p.Asn120Asp,-0.02,0.04,2,N450D +urn:mavedb:00000044-b-2#4763,NA,NA,p.Asn120Cys,-0.87,-0.77,1,N450C +urn:mavedb:00000044-b-2#4764,NA,NA,p.Asn120Cys,-0.67,-0.77,2,N450C +urn:mavedb:00000044-b-2#4785,NA,NA,p.Asn120Gln,0.01,0.04,1,N450Q +urn:mavedb:00000044-b-2#4786,NA,NA,p.Asn120Gln,0.06,0.04,2,N450Q +urn:mavedb:00000044-b-2#4767,NA,NA,p.Asn120Glu,0.14,0.15,1,N450E +urn:mavedb:00000044-b-2#4768,NA,NA,p.Asn120Glu,0.17,0.15,2,N450E +urn:mavedb:00000044-b-2#4771,NA,NA,p.Asn120Gly,-0.1,-0.1,1,N450G +urn:mavedb:00000044-b-2#4772,NA,NA,p.Asn120Gly,-0.09,-0.1,2,N450G +urn:mavedb:00000044-b-2#4773,NA,NA,p.Asn120His,-0.01,-0.1,1,N450H +urn:mavedb:00000044-b-2#4774,NA,NA,p.Asn120His,-0.18,-0.1,2,N450H +urn:mavedb:00000044-b-2#4775,NA,NA,p.Asn120Ile,-0.48,-0.43,1,N450I +urn:mavedb:00000044-b-2#4776,NA,NA,p.Asn120Ile,-0.37,-0.43,2,N450I +urn:mavedb:00000044-b-2#4779,NA,NA,p.Asn120Leu,-0.37,-0.39,1,N450L +urn:mavedb:00000044-b-2#4780,NA,NA,p.Asn120Leu,-0.41,-0.39,2,N450L +urn:mavedb:00000044-b-2#4777,NA,NA,p.Asn120Lys,0.01,-0.01,1,N450K +urn:mavedb:00000044-b-2#4778,NA,NA,p.Asn120Lys,-0.03,-0.01,2,N450K +urn:mavedb:00000044-b-2#4781,NA,NA,p.Asn120Met,-0.23,-0.29,1,N450M +urn:mavedb:00000044-b-2#4782,NA,NA,p.Asn120Met,-0.34,-0.29,2,N450M +urn:mavedb:00000044-b-2#4769,NA,NA,p.Asn120Phe,-0.68,-0.58,1,N450F +urn:mavedb:00000044-b-2#4770,NA,NA,p.Asn120Phe,-0.48,-0.58,2,N450F +urn:mavedb:00000044-b-2#4783,NA,NA,p.Asn120Pro,-0.14,-0.14,1,N450P +urn:mavedb:00000044-b-2#4784,NA,NA,p.Asn120Pro,-0.15,-0.14,2,N450P +urn:mavedb:00000044-b-2#4789,NA,NA,p.Asn120Ser,0.01,-0.02,1,N450S +urn:mavedb:00000044-b-2#4790,NA,NA,p.Asn120Ser,-0.04,-0.02,2,N450S +urn:mavedb:00000044-b-2#4791,NA,NA,p.Asn120Thr,0.1,0.08,1,N450T +urn:mavedb:00000044-b-2#4792,NA,NA,p.Asn120Thr,0.05,0.08,2,N450T +urn:mavedb:00000044-b-2#4795,NA,NA,p.Asn120Trp,-0.62,-0.61,1,N450W +urn:mavedb:00000044-b-2#4796,NA,NA,p.Asn120Trp,-0.6,-0.61,2,N450W +urn:mavedb:00000044-b-2#4797,NA,NA,p.Asn120Tyr,-0.39,-0.43,1,N450Y +urn:mavedb:00000044-b-2#4798,NA,NA,p.Asn120Tyr,-0.47,-0.43,2,N450Y +urn:mavedb:00000044-b-2#4793,NA,NA,p.Asn120Val,-0.27,-0.33,1,N450V +urn:mavedb:00000044-b-2#4794,NA,NA,p.Asn120Val,-0.39,-0.33,2,N450V +urn:mavedb:00000044-b-2#519,NA,NA,p.Asn13*,-4.66,-4.65,1,N343 +urn:mavedb:00000044-b-2#520,NA,NA,p.Asn13*,-4.64,-4.65,2,N343 +urn:mavedb:00000044-b-2#5199,NA,NA,p.Asn130*,-4.59,-4.58,1,N460 +urn:mavedb:00000044-b-2#5200,NA,NA,p.Asn130*,-4.56,-4.58,2,N460 +urn:mavedb:00000044-b-2#5161,NA,NA,p.Asn130Ala,0.04,0.02,1,N460A +urn:mavedb:00000044-b-2#5162,NA,NA,p.Asn130Ala,0.01,0.02,2,N460A +urn:mavedb:00000044-b-2#5187,NA,NA,p.Asn130Arg,0.16,0.09,1,N460R +urn:mavedb:00000044-b-2#5188,NA,NA,p.Asn130Arg,0.02,0.09,2,N460R +urn:mavedb:00000044-b-2#5165,NA,NA,p.Asn130Asp,-0.59,-0.42,1,N460D +urn:mavedb:00000044-b-2#5166,NA,NA,p.Asn130Asp,-0.24,-0.42,2,N460D +urn:mavedb:00000044-b-2#5163,NA,NA,p.Asn130Cys,-0.18,-0.27,1,N460C +urn:mavedb:00000044-b-2#5164,NA,NA,p.Asn130Cys,-0.37,-0.27,2,N460C +urn:mavedb:00000044-b-2#5185,NA,NA,p.Asn130Gln,-0.24,-0.15,1,N460Q +urn:mavedb:00000044-b-2#5186,NA,NA,p.Asn130Gln,-0.07,-0.15,2,N460Q +urn:mavedb:00000044-b-2#5167,NA,NA,p.Asn130Glu,-0.28,-0.26,1,N460E +urn:mavedb:00000044-b-2#5168,NA,NA,p.Asn130Glu,-0.24,-0.26,2,N460E +urn:mavedb:00000044-b-2#5171,NA,NA,p.Asn130Gly,-0.82,-0.79,1,N460G +urn:mavedb:00000044-b-2#5172,NA,NA,p.Asn130Gly,-0.76,-0.79,2,N460G +urn:mavedb:00000044-b-2#5173,NA,NA,p.Asn130His,-0.03,-0.02,1,N460H +urn:mavedb:00000044-b-2#5174,NA,NA,p.Asn130His,-0.01,-0.02,2,N460H +urn:mavedb:00000044-b-2#5175,NA,NA,p.Asn130Ile,-0.02,-0.08,1,N460I +urn:mavedb:00000044-b-2#5176,NA,NA,p.Asn130Ile,-0.15,-0.08,2,N460I +urn:mavedb:00000044-b-2#5179,NA,NA,p.Asn130Leu,-0.15,-0.17,1,N460L +urn:mavedb:00000044-b-2#5180,NA,NA,p.Asn130Leu,-0.19,-0.17,2,N460L +urn:mavedb:00000044-b-2#5177,NA,NA,p.Asn130Lys,0.25,0.16,1,N460K +urn:mavedb:00000044-b-2#5178,NA,NA,p.Asn130Lys,0.08,0.16,2,N460K +urn:mavedb:00000044-b-2#5181,NA,NA,p.Asn130Met,-0.3,-0.29,1,N460M +urn:mavedb:00000044-b-2#5182,NA,NA,p.Asn130Met,-0.27,-0.29,2,N460M +urn:mavedb:00000044-b-2#5169,NA,NA,p.Asn130Phe,-0.52,-0.44,1,N460F +urn:mavedb:00000044-b-2#5170,NA,NA,p.Asn130Phe,-0.36,-0.44,2,N460F +urn:mavedb:00000044-b-2#5183,NA,NA,p.Asn130Pro,0.23,0.07,1,N460P +urn:mavedb:00000044-b-2#5184,NA,NA,p.Asn130Pro,-0.08,0.07,2,N460P +urn:mavedb:00000044-b-2#5189,NA,NA,p.Asn130Ser,-0.12,-0.15,1,N460S +urn:mavedb:00000044-b-2#5190,NA,NA,p.Asn130Ser,-0.18,-0.15,2,N460S +urn:mavedb:00000044-b-2#5191,NA,NA,p.Asn130Thr,0.03,-0.05,1,N460T +urn:mavedb:00000044-b-2#5192,NA,NA,p.Asn130Thr,-0.14,-0.05,2,N460T +urn:mavedb:00000044-b-2#5195,NA,NA,p.Asn130Trp,-1.07,-1.04,1,N460W +urn:mavedb:00000044-b-2#5196,NA,NA,p.Asn130Trp,-1.01,-1.04,2,N460W +urn:mavedb:00000044-b-2#5197,NA,NA,p.Asn130Tyr,-0.27,-0.32,1,N460Y +urn:mavedb:00000044-b-2#5198,NA,NA,p.Asn130Tyr,-0.37,-0.32,2,N460Y +urn:mavedb:00000044-b-2#5193,NA,NA,p.Asn130Val,-0.06,-0.08,1,N460V +urn:mavedb:00000044-b-2#5194,NA,NA,p.Asn130Val,-0.1,-0.08,2,N460V +urn:mavedb:00000044-b-2#481,NA,NA,p.Asn13Ala,-1.64,-1.52,1,N343A +urn:mavedb:00000044-b-2#482,NA,NA,p.Asn13Ala,-1.4,-1.52,2,N343A +urn:mavedb:00000044-b-2#507,NA,NA,p.Asn13Arg,-3.29,-2.55,1,N343R +urn:mavedb:00000044-b-2#508,NA,NA,p.Asn13Arg,-1.82,-2.55,2,N343R +urn:mavedb:00000044-b-2#485,NA,NA,p.Asn13Asp,-1.71,-1.67,1,N343D +urn:mavedb:00000044-b-2#486,NA,NA,p.Asn13Asp,-1.63,-1.67,2,N343D +urn:mavedb:00000044-b-2#483,NA,NA,p.Asn13Cys,-2.19,-2.18,1,N343C +urn:mavedb:00000044-b-2#484,NA,NA,p.Asn13Cys,-2.18,-2.18,2,N343C +urn:mavedb:00000044-b-2#505,NA,NA,p.Asn13Gln,-1.29,-1.4,1,N343Q +urn:mavedb:00000044-b-2#506,NA,NA,p.Asn13Gln,-1.5,-1.4,2,N343Q +urn:mavedb:00000044-b-2#487,NA,NA,p.Asn13Glu,-1.81,-1.7,1,N343E +urn:mavedb:00000044-b-2#488,NA,NA,p.Asn13Glu,-1.59,-1.7,2,N343E +urn:mavedb:00000044-b-2#491,NA,NA,p.Asn13Gly,-1.42,-1.35,1,N343G +urn:mavedb:00000044-b-2#492,NA,NA,p.Asn13Gly,-1.28,-1.35,2,N343G +urn:mavedb:00000044-b-2#493,NA,NA,p.Asn13His,-1.28,-1.45,1,N343H +urn:mavedb:00000044-b-2#494,NA,NA,p.Asn13His,-1.63,-1.45,2,N343H +urn:mavedb:00000044-b-2#495,NA,NA,p.Asn13Ile,-3.21,-3.06,1,N343I +urn:mavedb:00000044-b-2#496,NA,NA,p.Asn13Ile,-2.91,-3.06,2,N343I +urn:mavedb:00000044-b-2#499,NA,NA,p.Asn13Leu,-3.02,-2.58,1,N343L +urn:mavedb:00000044-b-2#500,NA,NA,p.Asn13Leu,-2.14,-2.58,2,N343L +urn:mavedb:00000044-b-2#497,NA,NA,p.Asn13Lys,-3,-2.33,1,N343K +urn:mavedb:00000044-b-2#498,NA,NA,p.Asn13Lys,-1.66,-2.33,2,N343K +urn:mavedb:00000044-b-2#501,NA,NA,p.Asn13Met,-3.57,-2.85,1,N343M +urn:mavedb:00000044-b-2#502,NA,NA,p.Asn13Met,-2.13,-2.85,2,N343M +urn:mavedb:00000044-b-2#489,NA,NA,p.Asn13Phe,-3.09,-2.57,1,N343F +urn:mavedb:00000044-b-2#490,NA,NA,p.Asn13Phe,-2.05,-2.57,2,N343F +urn:mavedb:00000044-b-2#503,NA,NA,p.Asn13Pro,-3.34,-3.2,1,N343P +urn:mavedb:00000044-b-2#504,NA,NA,p.Asn13Pro,-3.07,-3.2,2,N343P +urn:mavedb:00000044-b-2#509,NA,NA,p.Asn13Ser,-2.03,-2.58,1,N343S +urn:mavedb:00000044-b-2#510,NA,NA,p.Asn13Ser,-3.13,-2.58,2,N343S +urn:mavedb:00000044-b-2#511,NA,NA,p.Asn13Thr,-1.98,-2.46,1,N343T +urn:mavedb:00000044-b-2#512,NA,NA,p.Asn13Thr,-2.94,-2.46,2,N343T +urn:mavedb:00000044-b-2#515,NA,NA,p.Asn13Trp,-3.01,-2.94,1,N343W +urn:mavedb:00000044-b-2#516,NA,NA,p.Asn13Trp,-2.87,-2.94,2,N343W +urn:mavedb:00000044-b-2#517,NA,NA,p.Asn13Tyr,-2.09,-2.14,1,N343Y +urn:mavedb:00000044-b-2#518,NA,NA,p.Asn13Tyr,-2.2,-2.14,2,N343Y +urn:mavedb:00000044-b-2#513,NA,NA,p.Asn13Val,-3.12,-3.11,1,N343V +urn:mavedb:00000044-b-2#514,NA,NA,p.Asn13Val,-3.1,-3.11,2,N343V +urn:mavedb:00000044-b-2#6039,NA,NA,p.Asn151*,-4.6,-4.58,1,N481 +urn:mavedb:00000044-b-2#6040,NA,NA,p.Asn151*,-4.55,-4.58,2,N481 +urn:mavedb:00000044-b-2#6001,NA,NA,p.Asn151Ala,-0.22,-0.2,1,N481A +urn:mavedb:00000044-b-2#6002,NA,NA,p.Asn151Ala,-0.18,-0.2,2,N481A +urn:mavedb:00000044-b-2#6027,NA,NA,p.Asn151Arg,-0.06,-0.09,1,N481R +urn:mavedb:00000044-b-2#6028,NA,NA,p.Asn151Arg,-0.12,-0.09,2,N481R +urn:mavedb:00000044-b-2#6005,NA,NA,p.Asn151Asp,-0.11,-0.08,1,N481D +urn:mavedb:00000044-b-2#6006,NA,NA,p.Asn151Asp,-0.05,-0.08,2,N481D +urn:mavedb:00000044-b-2#6003,NA,NA,p.Asn151Cys,-0.29,-0.34,1,N481C +urn:mavedb:00000044-b-2#6004,NA,NA,p.Asn151Cys,-0.4,-0.34,2,N481C +urn:mavedb:00000044-b-2#6025,NA,NA,p.Asn151Gln,-0.05,-0.03,1,N481Q +urn:mavedb:00000044-b-2#6026,NA,NA,p.Asn151Gln,-0.01,-0.03,2,N481Q +urn:mavedb:00000044-b-2#6007,NA,NA,p.Asn151Glu,-0.16,-0.15,1,N481E +urn:mavedb:00000044-b-2#6008,NA,NA,p.Asn151Glu,-0.14,-0.15,2,N481E +urn:mavedb:00000044-b-2#6011,NA,NA,p.Asn151Gly,0.09,0.04,1,N481G +urn:mavedb:00000044-b-2#6012,NA,NA,p.Asn151Gly,-0.02,0.04,2,N481G +urn:mavedb:00000044-b-2#6013,NA,NA,p.Asn151His,-0.06,-0.16,1,N481H +urn:mavedb:00000044-b-2#6014,NA,NA,p.Asn151His,-0.27,-0.16,2,N481H +urn:mavedb:00000044-b-2#6015,NA,NA,p.Asn151Ile,-0.77,-0.81,1,N481I +urn:mavedb:00000044-b-2#6016,NA,NA,p.Asn151Ile,-0.84,-0.81,2,N481I +urn:mavedb:00000044-b-2#6019,NA,NA,p.Asn151Leu,-0.25,-0.42,1,N481L +urn:mavedb:00000044-b-2#6020,NA,NA,p.Asn151Leu,-0.59,-0.42,2,N481L +urn:mavedb:00000044-b-2#6017,NA,NA,p.Asn151Lys,-0.07,-0.11,1,N481K +urn:mavedb:00000044-b-2#6018,NA,NA,p.Asn151Lys,-0.15,-0.11,2,N481K +urn:mavedb:00000044-b-2#6021,NA,NA,p.Asn151Met,-0.4,-0.39,1,N481M +urn:mavedb:00000044-b-2#6022,NA,NA,p.Asn151Met,-0.38,-0.39,2,N481M +urn:mavedb:00000044-b-2#6009,NA,NA,p.Asn151Phe,-0.25,-0.29,1,N481F +urn:mavedb:00000044-b-2#6010,NA,NA,p.Asn151Phe,-0.33,-0.29,2,N481F +urn:mavedb:00000044-b-2#6023,NA,NA,p.Asn151Pro,-0.96,-0.95,1,N481P +urn:mavedb:00000044-b-2#6024,NA,NA,p.Asn151Pro,-0.94,-0.95,2,N481P +urn:mavedb:00000044-b-2#6029,NA,NA,p.Asn151Ser,-0.18,-0.16,1,N481S +urn:mavedb:00000044-b-2#6030,NA,NA,p.Asn151Ser,-0.14,-0.16,2,N481S +urn:mavedb:00000044-b-2#6031,NA,NA,p.Asn151Thr,-0.23,-0.26,1,N481T +urn:mavedb:00000044-b-2#6032,NA,NA,p.Asn151Thr,-0.29,-0.26,2,N481T +urn:mavedb:00000044-b-2#6035,NA,NA,p.Asn151Trp,-0.98,-1.05,1,N481W +urn:mavedb:00000044-b-2#6036,NA,NA,p.Asn151Trp,-1.12,-1.05,2,N481W +urn:mavedb:00000044-b-2#6037,NA,NA,p.Asn151Tyr,-0.49,-0.32,1,N481Y +urn:mavedb:00000044-b-2#6038,NA,NA,p.Asn151Tyr,-0.16,-0.32,2,N481Y +urn:mavedb:00000044-b-2#6033,NA,NA,p.Asn151Val,-0.64,-0.49,1,N481V +urn:mavedb:00000044-b-2#6034,NA,NA,p.Asn151Val,-0.35,-0.49,2,N481V +urn:mavedb:00000044-b-2#6279,NA,NA,p.Asn157*,-4.58,-4.54,1,N487 +urn:mavedb:00000044-b-2#6280,NA,NA,p.Asn157*,-4.49,-4.54,2,N487 +urn:mavedb:00000044-b-2#6241,NA,NA,p.Asn157Ala,-0.17,-0.22,1,N487A +urn:mavedb:00000044-b-2#6242,NA,NA,p.Asn157Ala,-0.26,-0.22,2,N487A +urn:mavedb:00000044-b-2#6267,NA,NA,p.Asn157Arg,-0.18,-0.25,1,N487R +urn:mavedb:00000044-b-2#6268,NA,NA,p.Asn157Arg,-0.32,-0.25,2,N487R +urn:mavedb:00000044-b-2#6245,NA,NA,p.Asn157Asp,0.05,0.07,1,N487D +urn:mavedb:00000044-b-2#6246,NA,NA,p.Asn157Asp,0.1,0.07,2,N487D +urn:mavedb:00000044-b-2#6243,NA,NA,p.Asn157Cys,-0.53,-0.49,1,N487C +urn:mavedb:00000044-b-2#6244,NA,NA,p.Asn157Cys,-0.46,-0.49,2,N487C +urn:mavedb:00000044-b-2#6265,NA,NA,p.Asn157Gln,-0.08,0.15,1,N487Q +urn:mavedb:00000044-b-2#6266,NA,NA,p.Asn157Gln,0.38,0.15,2,N487Q +urn:mavedb:00000044-b-2#6247,NA,NA,p.Asn157Glu,0.06,-0.01,1,N487E +urn:mavedb:00000044-b-2#6248,NA,NA,p.Asn157Glu,-0.08,-0.01,2,N487E +urn:mavedb:00000044-b-2#6251,NA,NA,p.Asn157Gly,0.03,0.1,1,N487G +urn:mavedb:00000044-b-2#6252,NA,NA,p.Asn157Gly,0.16,0.1,2,N487G +urn:mavedb:00000044-b-2#6253,NA,NA,p.Asn157His,-0.22,-0.3,1,N487H +urn:mavedb:00000044-b-2#6254,NA,NA,p.Asn157His,-0.39,-0.3,2,N487H +urn:mavedb:00000044-b-2#6255,NA,NA,p.Asn157Ile,-1.76,-1.7,1,N487I +urn:mavedb:00000044-b-2#6256,NA,NA,p.Asn157Ile,-1.65,-1.7,2,N487I +urn:mavedb:00000044-b-2#6259,NA,NA,p.Asn157Leu,-0.4,-0.37,1,N487L +urn:mavedb:00000044-b-2#6260,NA,NA,p.Asn157Leu,-0.34,-0.37,2,N487L +urn:mavedb:00000044-b-2#6257,NA,NA,p.Asn157Lys,-0.12,-0.09,1,N487K +urn:mavedb:00000044-b-2#6258,NA,NA,p.Asn157Lys,-0.07,-0.09,2,N487K +urn:mavedb:00000044-b-2#6261,NA,NA,p.Asn157Met,-0.26,-0.27,1,N487M +urn:mavedb:00000044-b-2#6262,NA,NA,p.Asn157Met,-0.28,-0.27,2,N487M +urn:mavedb:00000044-b-2#6249,NA,NA,p.Asn157Phe,-0.65,-0.63,1,N487F +urn:mavedb:00000044-b-2#6250,NA,NA,p.Asn157Phe,-0.62,-0.63,2,N487F +urn:mavedb:00000044-b-2#6263,NA,NA,p.Asn157Pro,-1.61,-1.34,1,N487P +urn:mavedb:00000044-b-2#6264,NA,NA,p.Asn157Pro,-1.07,-1.34,2,N487P +urn:mavedb:00000044-b-2#6269,NA,NA,p.Asn157Ser,-0.26,-0.2,1,N487S +urn:mavedb:00000044-b-2#6270,NA,NA,p.Asn157Ser,-0.14,-0.2,2,N487S +urn:mavedb:00000044-b-2#6271,NA,NA,p.Asn157Thr,-0.4,-0.38,1,N487T +urn:mavedb:00000044-b-2#6272,NA,NA,p.Asn157Thr,-0.36,-0.38,2,N487T +urn:mavedb:00000044-b-2#6275,NA,NA,p.Asn157Trp,-0.6,-0.53,1,N487W +urn:mavedb:00000044-b-2#6276,NA,NA,p.Asn157Trp,-0.46,-0.53,2,N487W +urn:mavedb:00000044-b-2#6277,NA,NA,p.Asn157Tyr,-0.77,-0.72,1,N487Y +urn:mavedb:00000044-b-2#6278,NA,NA,p.Asn157Tyr,-0.66,-0.72,2,N487Y +urn:mavedb:00000044-b-2#6273,NA,NA,p.Asn157Val,-1.59,-1.64,1,N487V +urn:mavedb:00000044-b-2#6274,NA,NA,p.Asn157Val,-1.7,-1.64,2,N487V +urn:mavedb:00000044-b-2#6839,NA,NA,p.Asn171*,-4.58,-4.23,1,N501 +urn:mavedb:00000044-b-2#6840,NA,NA,p.Asn171*,-3.89,-4.23,2,N501 +urn:mavedb:00000044-b-2#6801,NA,NA,p.Asn171Ala,0.42,0.07,1,N501A +urn:mavedb:00000044-b-2#6802,NA,NA,p.Asn171Ala,-0.29,0.07,2,N501A +urn:mavedb:00000044-b-2#6827,NA,NA,p.Asn171Arg,-0.05,-0.07,1,N501R +urn:mavedb:00000044-b-2#6828,NA,NA,p.Asn171Arg,-0.1,-0.07,2,N501R +urn:mavedb:00000044-b-2#6805,NA,NA,p.Asn171Asp,0.09,0.08,1,N501D +urn:mavedb:00000044-b-2#6806,NA,NA,p.Asn171Asp,0.07,0.08,2,N501D +urn:mavedb:00000044-b-2#6803,NA,NA,p.Asn171Cys,-0.54,-0.47,1,N501C +urn:mavedb:00000044-b-2#6804,NA,NA,p.Asn171Cys,-0.4,-0.47,2,N501C +urn:mavedb:00000044-b-2#6825,NA,NA,p.Asn171Gln,0.02,0.14,1,N501Q +urn:mavedb:00000044-b-2#6826,NA,NA,p.Asn171Gln,0.26,0.14,2,N501Q +urn:mavedb:00000044-b-2#6807,NA,NA,p.Asn171Glu,-0.2,-0.42,1,N501E +urn:mavedb:00000044-b-2#6808,NA,NA,p.Asn171Glu,-0.64,-0.42,2,N501E +urn:mavedb:00000044-b-2#6811,NA,NA,p.Asn171Gly,-0.21,-0.32,1,N501G +urn:mavedb:00000044-b-2#6812,NA,NA,p.Asn171Gly,-0.44,-0.32,2,N501G +urn:mavedb:00000044-b-2#6813,NA,NA,p.Asn171His,-0.23,-0.24,1,N501H +urn:mavedb:00000044-b-2#6814,NA,NA,p.Asn171His,-0.25,-0.24,2,N501H +urn:mavedb:00000044-b-2#6815,NA,NA,p.Asn171Ile,-0.55,-0.7,1,N501I +urn:mavedb:00000044-b-2#6816,NA,NA,p.Asn171Ile,-0.84,-0.7,2,N501I +urn:mavedb:00000044-b-2#6819,NA,NA,p.Asn171Leu,-0.01,-0.04,1,N501L +urn:mavedb:00000044-b-2#6820,NA,NA,p.Asn171Leu,-0.06,-0.04,2,N501L +urn:mavedb:00000044-b-2#6817,NA,NA,p.Asn171Lys,-0.21,-0.1,1,N501K +urn:mavedb:00000044-b-2#6818,NA,NA,p.Asn171Lys,0,-0.1,2,N501K +urn:mavedb:00000044-b-2#6821,NA,NA,p.Asn171Met,0.48,0.33,1,N501M +urn:mavedb:00000044-b-2#6822,NA,NA,p.Asn171Met,0.18,0.33,2,N501M +urn:mavedb:00000044-b-2#6809,NA,NA,p.Asn171Phe,-0.03,-0.1,1,N501F +urn:mavedb:00000044-b-2#6810,NA,NA,p.Asn171Phe,-0.16,-0.1,2,N501F +urn:mavedb:00000044-b-2#6823,NA,NA,p.Asn171Pro,-0.72,-0.62,1,N501P +urn:mavedb:00000044-b-2#6824,NA,NA,p.Asn171Pro,-0.51,-0.62,2,N501P +urn:mavedb:00000044-b-2#6829,NA,NA,p.Asn171Ser,-0.02,-0.03,1,N501S +urn:mavedb:00000044-b-2#6830,NA,NA,p.Asn171Ser,-0.04,-0.03,2,N501S +urn:mavedb:00000044-b-2#6831,NA,NA,p.Asn171Thr,-0.35,-0.25,1,N501T +urn:mavedb:00000044-b-2#6832,NA,NA,p.Asn171Thr,-0.16,-0.25,2,N501T +urn:mavedb:00000044-b-2#6835,NA,NA,p.Asn171Trp,0.05,0.1,1,N501W +urn:mavedb:00000044-b-2#6836,NA,NA,p.Asn171Trp,0.15,0.1,2,N501W +urn:mavedb:00000044-b-2#6837,NA,NA,p.Asn171Tyr,-0.06,-0.14,1,N501Y +urn:mavedb:00000044-b-2#6838,NA,NA,p.Asn171Tyr,-0.22,-0.14,2,N501Y +urn:mavedb:00000044-b-2#6833,NA,NA,p.Asn171Val,-0.21,-0.19,1,N501V +urn:mavedb:00000044-b-2#6834,NA,NA,p.Asn171Val,-0.17,-0.19,2,N501V +urn:mavedb:00000044-b-2#1,NA,NA,p.Asn1Ala,-0.14,-0.11,1,N331A +urn:mavedb:00000044-b-2#2,NA,NA,p.Asn1Ala,-0.08,-0.11,2,N331A +urn:mavedb:00000044-b-2#27,NA,NA,p.Asn1Arg,-0.65,-0.44,1,N331R +urn:mavedb:00000044-b-2#28,NA,NA,p.Asn1Arg,-0.23,-0.44,2,N331R +urn:mavedb:00000044-b-2#5,NA,NA,p.Asn1Asp,-0.75,-0.44,1,N331D +urn:mavedb:00000044-b-2#6,NA,NA,p.Asn1Asp,-0.12,-0.44,2,N331D +urn:mavedb:00000044-b-2#3,NA,NA,p.Asn1Cys,-1.56,-1.26,1,N331C +urn:mavedb:00000044-b-2#4,NA,NA,p.Asn1Cys,-0.97,-1.26,2,N331C +urn:mavedb:00000044-b-2#25,NA,NA,p.Asn1Gln,-0.31,-0.53,1,N331Q +urn:mavedb:00000044-b-2#26,NA,NA,p.Asn1Gln,-0.75,-0.53,2,N331Q +urn:mavedb:00000044-b-2#7,NA,NA,p.Asn1Glu,-0.39,-0.31,1,N331E +urn:mavedb:00000044-b-2#8,NA,NA,p.Asn1Glu,-0.24,-0.31,2,N331E +urn:mavedb:00000044-b-2#11,NA,NA,p.Asn1Gly,-0.21,-0.25,1,N331G +urn:mavedb:00000044-b-2#12,NA,NA,p.Asn1Gly,-0.29,-0.25,2,N331G +urn:mavedb:00000044-b-2#13,NA,NA,p.Asn1His,-0.86,-0.61,1,N331H +urn:mavedb:00000044-b-2#14,NA,NA,p.Asn1His,-0.36,-0.61,2,N331H +urn:mavedb:00000044-b-2#15,NA,NA,p.Asn1Ile,-1.05,-0.85,1,N331I +urn:mavedb:00000044-b-2#16,NA,NA,p.Asn1Ile,-0.65,-0.85,2,N331I +urn:mavedb:00000044-b-2#19,NA,NA,p.Asn1Leu,-0.81,-0.75,1,N331L +urn:mavedb:00000044-b-2#20,NA,NA,p.Asn1Leu,-0.69,-0.75,2,N331L +urn:mavedb:00000044-b-2#17,NA,NA,p.Asn1Lys,-0.17,-0.2,1,N331K +urn:mavedb:00000044-b-2#18,NA,NA,p.Asn1Lys,-0.24,-0.2,2,N331K +urn:mavedb:00000044-b-2#21,NA,NA,p.Asn1Met,-1.02,-0.75,1,N331M +urn:mavedb:00000044-b-2#22,NA,NA,p.Asn1Met,-0.48,-0.75,2,N331M +urn:mavedb:00000044-b-2#9,NA,NA,p.Asn1Phe,-0.83,-0.7,1,N331F +urn:mavedb:00000044-b-2#10,NA,NA,p.Asn1Phe,-0.57,-0.7,2,N331F +urn:mavedb:00000044-b-2#23,NA,NA,p.Asn1Pro,-0.1,-0.21,1,N331P +urn:mavedb:00000044-b-2#24,NA,NA,p.Asn1Pro,-0.33,-0.21,2,N331P +urn:mavedb:00000044-b-2#29,NA,NA,p.Asn1Ser,-0.34,-0.33,1,N331S +urn:mavedb:00000044-b-2#30,NA,NA,p.Asn1Ser,-0.33,-0.33,2,N331S +urn:mavedb:00000044-b-2#31,NA,NA,p.Asn1Thr,-0.42,-0.34,1,N331T +urn:mavedb:00000044-b-2#32,NA,NA,p.Asn1Thr,-0.26,-0.34,2,N331T +urn:mavedb:00000044-b-2#35,NA,NA,p.Asn1Trp,-0.88,-1.12,1,N331W +urn:mavedb:00000044-b-2#36,NA,NA,p.Asn1Trp,-1.36,-1.12,2,N331W +urn:mavedb:00000044-b-2#37,NA,NA,p.Asn1Tyr,-1.15,-1.02,1,N331Y +urn:mavedb:00000044-b-2#38,NA,NA,p.Asn1Tyr,-0.88,-1.02,2,N331Y +urn:mavedb:00000044-b-2#33,NA,NA,p.Asn1Val,-0.43,-0.61,1,N331V +urn:mavedb:00000044-b-2#34,NA,NA,p.Asn1Val,-0.79,-0.61,2,N331V +urn:mavedb:00000044-b-2#959,NA,NA,p.Asn24*,-4.6,-4.38,1,N354 +urn:mavedb:00000044-b-2#960,NA,NA,p.Asn24*,-4.16,-4.38,2,N354 +urn:mavedb:00000044-b-2#921,NA,NA,p.Asn24Ala,-0.53,-0.45,1,N354A +urn:mavedb:00000044-b-2#922,NA,NA,p.Asn24Ala,-0.37,-0.45,2,N354A +urn:mavedb:00000044-b-2#947,NA,NA,p.Asn24Arg,0.27,0.14,1,N354R +urn:mavedb:00000044-b-2#948,NA,NA,p.Asn24Arg,0.02,0.14,2,N354R +urn:mavedb:00000044-b-2#925,NA,NA,p.Asn24Asp,0.03,0.13,1,N354D +urn:mavedb:00000044-b-2#926,NA,NA,p.Asn24Asp,0.23,0.13,2,N354D +urn:mavedb:00000044-b-2#923,NA,NA,p.Asn24Cys,-0.92,-1,1,N354C +urn:mavedb:00000044-b-2#924,NA,NA,p.Asn24Cys,-1.08,-1,2,N354C +urn:mavedb:00000044-b-2#945,NA,NA,p.Asn24Gln,0.91,0.52,1,N354Q +urn:mavedb:00000044-b-2#946,NA,NA,p.Asn24Gln,0.13,0.52,2,N354Q +urn:mavedb:00000044-b-2#927,NA,NA,p.Asn24Glu,0.59,0.64,1,N354E +urn:mavedb:00000044-b-2#928,NA,NA,p.Asn24Glu,0.7,0.64,2,N354E +urn:mavedb:00000044-b-2#931,NA,NA,p.Asn24Gly,-1.07,-0.74,1,N354G +urn:mavedb:00000044-b-2#932,NA,NA,p.Asn24Gly,-0.41,-0.74,2,N354G +urn:mavedb:00000044-b-2#933,NA,NA,p.Asn24His,-0.21,-0.44,1,N354H +urn:mavedb:00000044-b-2#934,NA,NA,p.Asn24His,-0.66,-0.44,2,N354H +urn:mavedb:00000044-b-2#935,NA,NA,p.Asn24Ile,-1.25,-1.1,1,N354I +urn:mavedb:00000044-b-2#936,NA,NA,p.Asn24Ile,-0.95,-1.1,2,N354I +urn:mavedb:00000044-b-2#939,NA,NA,p.Asn24Leu,-1.53,-1.47,1,N354L +urn:mavedb:00000044-b-2#940,NA,NA,p.Asn24Leu,-1.42,-1.47,2,N354L +urn:mavedb:00000044-b-2#937,NA,NA,p.Asn24Lys,0,0.21,1,N354K +urn:mavedb:00000044-b-2#938,NA,NA,p.Asn24Lys,0.42,0.21,2,N354K +urn:mavedb:00000044-b-2#941,NA,NA,p.Asn24Met,-0.98,-0.91,1,N354M +urn:mavedb:00000044-b-2#942,NA,NA,p.Asn24Met,-0.84,-0.91,2,N354M +urn:mavedb:00000044-b-2#929,NA,NA,p.Asn24Phe,-1.8,-1.68,1,N354F +urn:mavedb:00000044-b-2#930,NA,NA,p.Asn24Phe,-1.56,-1.68,2,N354F +urn:mavedb:00000044-b-2#943,NA,NA,p.Asn24Pro,-2.41,-2.24,1,N354P +urn:mavedb:00000044-b-2#944,NA,NA,p.Asn24Pro,-2.08,-2.24,2,N354P +urn:mavedb:00000044-b-2#949,NA,NA,p.Asn24Ser,0.26,0.17,1,N354S +urn:mavedb:00000044-b-2#950,NA,NA,p.Asn24Ser,0.09,0.17,2,N354S +urn:mavedb:00000044-b-2#951,NA,NA,p.Asn24Thr,0.05,0.02,1,N354T +urn:mavedb:00000044-b-2#952,NA,NA,p.Asn24Thr,0,0.02,2,N354T +urn:mavedb:00000044-b-2#955,NA,NA,p.Asn24Trp,-2.11,-1.66,1,N354W +urn:mavedb:00000044-b-2#956,NA,NA,p.Asn24Trp,-1.22,-1.66,2,N354W +urn:mavedb:00000044-b-2#957,NA,NA,p.Asn24Tyr,-1.23,-1.22,1,N354Y +urn:mavedb:00000044-b-2#958,NA,NA,p.Asn24Tyr,-1.22,-1.22,2,N354Y +urn:mavedb:00000044-b-2#953,NA,NA,p.Asn24Val,-0.53,-0.58,1,N354V +urn:mavedb:00000044-b-2#954,NA,NA,p.Asn24Val,-0.64,-0.58,2,N354V +urn:mavedb:00000044-b-2#1199,NA,NA,p.Asn30*,-4.61,-4.58,1,N360 +urn:mavedb:00000044-b-2#1200,NA,NA,p.Asn30*,-4.54,-4.58,2,N360 +urn:mavedb:00000044-b-2#1161,NA,NA,p.Asn30Ala,-0.26,-1.09,1,N360A +urn:mavedb:00000044-b-2#1162,NA,NA,p.Asn30Ala,-1.93,-1.09,2,N360A +urn:mavedb:00000044-b-2#1187,NA,NA,p.Asn30Arg,-0.52,-0.53,1,N360R +urn:mavedb:00000044-b-2#1188,NA,NA,p.Asn30Arg,-0.54,-0.53,2,N360R +urn:mavedb:00000044-b-2#1165,NA,NA,p.Asn30Asp,0.52,0.28,1,N360D +urn:mavedb:00000044-b-2#1166,NA,NA,p.Asn30Asp,0.04,0.28,2,N360D +urn:mavedb:00000044-b-2#1163,NA,NA,p.Asn30Cys,-0.82,-0.96,1,N360C +urn:mavedb:00000044-b-2#1164,NA,NA,p.Asn30Cys,-1.1,-0.96,2,N360C +urn:mavedb:00000044-b-2#1185,NA,NA,p.Asn30Gln,-0.62,-0.7,1,N360Q +urn:mavedb:00000044-b-2#1186,NA,NA,p.Asn30Gln,-0.78,-0.7,2,N360Q +urn:mavedb:00000044-b-2#1167,NA,NA,p.Asn30Glu,-0.3,-0.33,1,N360E +urn:mavedb:00000044-b-2#1168,NA,NA,p.Asn30Glu,-0.37,-0.33,2,N360E +urn:mavedb:00000044-b-2#1171,NA,NA,p.Asn30Gly,0.07,-0.03,1,N360G +urn:mavedb:00000044-b-2#1172,NA,NA,p.Asn30Gly,-0.12,-0.03,2,N360G +urn:mavedb:00000044-b-2#1173,NA,NA,p.Asn30His,-0.42,-0.06,1,N360H +urn:mavedb:00000044-b-2#1174,NA,NA,p.Asn30His,0.3,-0.06,2,N360H +urn:mavedb:00000044-b-2#1175,NA,NA,p.Asn30Ile,-1.89,-1.83,1,N360I +urn:mavedb:00000044-b-2#1176,NA,NA,p.Asn30Ile,-1.77,-1.83,2,N360I +urn:mavedb:00000044-b-2#1179,NA,NA,p.Asn30Leu,-1.12,-1.02,1,N360L +urn:mavedb:00000044-b-2#1180,NA,NA,p.Asn30Leu,-0.92,-1.02,2,N360L +urn:mavedb:00000044-b-2#1177,NA,NA,p.Asn30Lys,-0.51,-0.47,1,N360K +urn:mavedb:00000044-b-2#1178,NA,NA,p.Asn30Lys,-0.44,-0.47,2,N360K +urn:mavedb:00000044-b-2#1181,NA,NA,p.Asn30Met,-0.82,-0.98,1,N360M +urn:mavedb:00000044-b-2#1182,NA,NA,p.Asn30Met,-1.13,-0.98,2,N360M +urn:mavedb:00000044-b-2#1169,NA,NA,p.Asn30Phe,0.06,-0.29,1,N360F +urn:mavedb:00000044-b-2#1170,NA,NA,p.Asn30Phe,-0.64,-0.29,2,N360F +urn:mavedb:00000044-b-2#1183,NA,NA,p.Asn30Pro,-2.87,-1.33,1,N360P +urn:mavedb:00000044-b-2#1184,NA,NA,p.Asn30Pro,0.21,-1.33,2,N360P +urn:mavedb:00000044-b-2#1189,NA,NA,p.Asn30Ser,-0.46,-0.57,1,N360S +urn:mavedb:00000044-b-2#1190,NA,NA,p.Asn30Ser,-0.67,-0.57,2,N360S +urn:mavedb:00000044-b-2#1191,NA,NA,p.Asn30Thr,-0.99,-1.16,1,N360T +urn:mavedb:00000044-b-2#1192,NA,NA,p.Asn30Thr,-1.33,-1.16,2,N360T +urn:mavedb:00000044-b-2#1195,NA,NA,p.Asn30Trp,-0.86,-0.73,1,N360W +urn:mavedb:00000044-b-2#1196,NA,NA,p.Asn30Trp,-0.6,-0.73,2,N360W +urn:mavedb:00000044-b-2#1197,NA,NA,p.Asn30Tyr,-1.3,-1.23,1,N360Y +urn:mavedb:00000044-b-2#1198,NA,NA,p.Asn30Tyr,-1.16,-1.23,2,N360Y +urn:mavedb:00000044-b-2#1193,NA,NA,p.Asn30Val,-1.89,-1.78,1,N360V +urn:mavedb:00000044-b-2#1194,NA,NA,p.Asn30Val,-1.66,-1.78,2,N360V +urn:mavedb:00000044-b-2#159,NA,NA,p.Asn4*,-4.7,-4.63,1,N334 +urn:mavedb:00000044-b-2#160,NA,NA,p.Asn4*,-4.56,-4.63,2,N334 +urn:mavedb:00000044-b-2#1599,NA,NA,p.Asn40*,-4.59,-4.55,1,N370 +urn:mavedb:00000044-b-2#1600,NA,NA,p.Asn40*,-4.5,-4.55,2,N370 +urn:mavedb:00000044-b-2#1561,NA,NA,p.Asn40Ala,-0.19,-0.25,1,N370A +urn:mavedb:00000044-b-2#1562,NA,NA,p.Asn40Ala,-0.31,-0.25,2,N370A +urn:mavedb:00000044-b-2#1587,NA,NA,p.Asn40Arg,-0.09,-0.16,1,N370R +urn:mavedb:00000044-b-2#1588,NA,NA,p.Asn40Arg,-0.23,-0.16,2,N370R +urn:mavedb:00000044-b-2#1565,NA,NA,p.Asn40Asp,0.06,-0.15,1,N370D +urn:mavedb:00000044-b-2#1566,NA,NA,p.Asn40Asp,-0.36,-0.15,2,N370D +urn:mavedb:00000044-b-2#1563,NA,NA,p.Asn40Cys,-1.13,-1.28,1,N370C +urn:mavedb:00000044-b-2#1564,NA,NA,p.Asn40Cys,-1.44,-1.28,2,N370C +urn:mavedb:00000044-b-2#1585,NA,NA,p.Asn40Gln,-0.06,-0.29,1,N370Q +urn:mavedb:00000044-b-2#1586,NA,NA,p.Asn40Gln,-0.51,-0.29,2,N370Q +urn:mavedb:00000044-b-2#1567,NA,NA,p.Asn40Glu,-0.1,-0.19,1,N370E +urn:mavedb:00000044-b-2#1568,NA,NA,p.Asn40Glu,-0.28,-0.19,2,N370E +urn:mavedb:00000044-b-2#1571,NA,NA,p.Asn40Gly,-0.07,-0.01,1,N370G +urn:mavedb:00000044-b-2#1572,NA,NA,p.Asn40Gly,0.06,-0.01,2,N370G +urn:mavedb:00000044-b-2#1573,NA,NA,p.Asn40His,-0.08,-0.13,1,N370H +urn:mavedb:00000044-b-2#1574,NA,NA,p.Asn40His,-0.19,-0.13,2,N370H +urn:mavedb:00000044-b-2#1575,NA,NA,p.Asn40Ile,-1.76,-1.76,1,N370I +urn:mavedb:00000044-b-2#1576,NA,NA,p.Asn40Ile,-1.76,-1.76,2,N370I +urn:mavedb:00000044-b-2#1579,NA,NA,p.Asn40Leu,-0.69,-0.73,1,N370L +urn:mavedb:00000044-b-2#1580,NA,NA,p.Asn40Leu,-0.77,-0.73,2,N370L +urn:mavedb:00000044-b-2#1577,NA,NA,p.Asn40Lys,-0.11,-0.04,1,N370K +urn:mavedb:00000044-b-2#1578,NA,NA,p.Asn40Lys,0.02,-0.04,2,N370K +urn:mavedb:00000044-b-2#1581,NA,NA,p.Asn40Met,-0.64,-0.63,1,N370M +urn:mavedb:00000044-b-2#1582,NA,NA,p.Asn40Met,-0.62,-0.63,2,N370M +urn:mavedb:00000044-b-2#1569,NA,NA,p.Asn40Phe,-1.05,-1.08,1,N370F +urn:mavedb:00000044-b-2#1570,NA,NA,p.Asn40Phe,-1.12,-1.08,2,N370F +urn:mavedb:00000044-b-2#1583,NA,NA,p.Asn40Pro,-0.33,-0.37,1,N370P +urn:mavedb:00000044-b-2#1584,NA,NA,p.Asn40Pro,-0.42,-0.37,2,N370P +urn:mavedb:00000044-b-2#1589,NA,NA,p.Asn40Ser,-0.19,-0.17,1,N370S +urn:mavedb:00000044-b-2#1590,NA,NA,p.Asn40Ser,-0.14,-0.17,2,N370S +urn:mavedb:00000044-b-2#1591,NA,NA,p.Asn40Thr,-0.48,-0.48,1,N370T +urn:mavedb:00000044-b-2#1592,NA,NA,p.Asn40Thr,-0.48,-0.48,2,N370T +urn:mavedb:00000044-b-2#1595,NA,NA,p.Asn40Trp,-1.32,-1.06,1,N370W +urn:mavedb:00000044-b-2#1596,NA,NA,p.Asn40Trp,-0.8,-1.06,2,N370W +urn:mavedb:00000044-b-2#1597,NA,NA,p.Asn40Tyr,-0.7,-0.81,1,N370Y +urn:mavedb:00000044-b-2#1598,NA,NA,p.Asn40Tyr,-0.91,-0.81,2,N370Y +urn:mavedb:00000044-b-2#1593,NA,NA,p.Asn40Val,-1.96,-1.69,1,N370V +urn:mavedb:00000044-b-2#1594,NA,NA,p.Asn40Val,-1.42,-1.69,2,N370V +urn:mavedb:00000044-b-2#121,NA,NA,p.Asn4Ala,-0.15,-0.12,1,N334A +urn:mavedb:00000044-b-2#122,NA,NA,p.Asn4Ala,-0.09,-0.12,2,N334A +urn:mavedb:00000044-b-2#147,NA,NA,p.Asn4Arg,-0.09,-0.12,1,N334R +urn:mavedb:00000044-b-2#148,NA,NA,p.Asn4Arg,-0.14,-0.12,2,N334R +urn:mavedb:00000044-b-2#125,NA,NA,p.Asn4Asp,-0.07,-0.04,1,N334D +urn:mavedb:00000044-b-2#126,NA,NA,p.Asn4Asp,-0.02,-0.04,2,N334D +urn:mavedb:00000044-b-2#123,NA,NA,p.Asn4Cys,-0.65,-0.57,1,N334C +urn:mavedb:00000044-b-2#124,NA,NA,p.Asn4Cys,-0.49,-0.57,2,N334C +urn:mavedb:00000044-b-2#145,NA,NA,p.Asn4Gln,-0.09,-0.08,1,N334Q +urn:mavedb:00000044-b-2#146,NA,NA,p.Asn4Gln,-0.06,-0.08,2,N334Q +urn:mavedb:00000044-b-2#127,NA,NA,p.Asn4Glu,-0.03,-0.05,1,N334E +urn:mavedb:00000044-b-2#128,NA,NA,p.Asn4Glu,-0.07,-0.05,2,N334E +urn:mavedb:00000044-b-2#131,NA,NA,p.Asn4Gly,-0.14,-0.21,1,N334G +urn:mavedb:00000044-b-2#132,NA,NA,p.Asn4Gly,-0.28,-0.21,2,N334G +urn:mavedb:00000044-b-2#133,NA,NA,p.Asn4His,-0.09,-0.12,1,N334H +urn:mavedb:00000044-b-2#134,NA,NA,p.Asn4His,-0.15,-0.12,2,N334H +urn:mavedb:00000044-b-2#135,NA,NA,p.Asn4Ile,-0.65,-0.67,1,N334I +urn:mavedb:00000044-b-2#136,NA,NA,p.Asn4Ile,-0.69,-0.67,2,N334I +urn:mavedb:00000044-b-2#139,NA,NA,p.Asn4Leu,-0.79,-0.72,1,N334L +urn:mavedb:00000044-b-2#140,NA,NA,p.Asn4Leu,-0.65,-0.72,2,N334L +urn:mavedb:00000044-b-2#137,NA,NA,p.Asn4Lys,0.1,-0.02,1,N334K +urn:mavedb:00000044-b-2#138,NA,NA,p.Asn4Lys,-0.13,-0.02,2,N334K +urn:mavedb:00000044-b-2#141,NA,NA,p.Asn4Met,-0.31,-0.4,1,N334M +urn:mavedb:00000044-b-2#142,NA,NA,p.Asn4Met,-0.5,-0.4,2,N334M +urn:mavedb:00000044-b-2#129,NA,NA,p.Asn4Phe,-0.77,-0.97,1,N334F +urn:mavedb:00000044-b-2#130,NA,NA,p.Asn4Phe,-1.17,-0.97,2,N334F +urn:mavedb:00000044-b-2#143,NA,NA,p.Asn4Pro,-0.62,-0.55,1,N334P +urn:mavedb:00000044-b-2#144,NA,NA,p.Asn4Pro,-0.47,-0.55,2,N334P +urn:mavedb:00000044-b-2#149,NA,NA,p.Asn4Ser,-0.19,-0.19,1,N334S +urn:mavedb:00000044-b-2#150,NA,NA,p.Asn4Ser,-0.19,-0.19,2,N334S +urn:mavedb:00000044-b-2#151,NA,NA,p.Asn4Thr,-0.02,-0.02,1,N334T +urn:mavedb:00000044-b-2#152,NA,NA,p.Asn4Thr,-0.02,-0.02,2,N334T +urn:mavedb:00000044-b-2#155,NA,NA,p.Asn4Trp,-0.97,-1.01,1,N334W +urn:mavedb:00000044-b-2#156,NA,NA,p.Asn4Trp,-1.06,-1.01,2,N334W +urn:mavedb:00000044-b-2#157,NA,NA,p.Asn4Tyr,-0.57,-0.61,1,N334Y +urn:mavedb:00000044-b-2#158,NA,NA,p.Asn4Tyr,-0.64,-0.61,2,N334Y +urn:mavedb:00000044-b-2#153,NA,NA,p.Asn4Val,-0.52,-0.47,1,N334V +urn:mavedb:00000044-b-2#154,NA,NA,p.Asn4Val,-0.42,-0.47,2,N334V +urn:mavedb:00000044-b-2#2319,NA,NA,p.Asn58*,-4.2,-4.39,1,N388 +urn:mavedb:00000044-b-2#2320,NA,NA,p.Asn58*,-4.58,-4.39,2,N388 +urn:mavedb:00000044-b-2#2281,NA,NA,p.Asn58Ala,-0.26,-0.38,1,N388A +urn:mavedb:00000044-b-2#2282,NA,NA,p.Asn58Ala,-0.5,-0.38,2,N388A +urn:mavedb:00000044-b-2#2307,NA,NA,p.Asn58Arg,-0.58,-0.49,1,N388R +urn:mavedb:00000044-b-2#2308,NA,NA,p.Asn58Arg,-0.39,-0.49,2,N388R +urn:mavedb:00000044-b-2#2285,NA,NA,p.Asn58Asp,-0.07,-0.12,1,N388D +urn:mavedb:00000044-b-2#2286,NA,NA,p.Asn58Asp,-0.17,-0.12,2,N388D +urn:mavedb:00000044-b-2#2283,NA,NA,p.Asn58Cys,-1.46,-1.17,1,N388C +urn:mavedb:00000044-b-2#2284,NA,NA,p.Asn58Cys,-0.87,-1.17,2,N388C +urn:mavedb:00000044-b-2#2305,NA,NA,p.Asn58Gln,-0.15,-0.18,1,N388Q +urn:mavedb:00000044-b-2#2306,NA,NA,p.Asn58Gln,-0.2,-0.18,2,N388Q +urn:mavedb:00000044-b-2#2287,NA,NA,p.Asn58Glu,-0.32,-0.37,1,N388E +urn:mavedb:00000044-b-2#2288,NA,NA,p.Asn58Glu,-0.42,-0.37,2,N388E +urn:mavedb:00000044-b-2#2291,NA,NA,p.Asn58Gly,-0.52,-0.43,1,N388G +urn:mavedb:00000044-b-2#2292,NA,NA,p.Asn58Gly,-0.35,-0.43,2,N388G +urn:mavedb:00000044-b-2#2293,NA,NA,p.Asn58His,-0.24,-0.28,1,N388H +urn:mavedb:00000044-b-2#2294,NA,NA,p.Asn58His,-0.32,-0.28,2,N388H +urn:mavedb:00000044-b-2#2295,NA,NA,p.Asn58Ile,-0.92,-1.05,1,N388I +urn:mavedb:00000044-b-2#2296,NA,NA,p.Asn58Ile,-1.19,-1.05,2,N388I +urn:mavedb:00000044-b-2#2299,NA,NA,p.Asn58Leu,-0.92,-0.94,1,N388L +urn:mavedb:00000044-b-2#2300,NA,NA,p.Asn58Leu,-0.96,-0.94,2,N388L +urn:mavedb:00000044-b-2#2297,NA,NA,p.Asn58Lys,-0.27,-0.26,1,N388K +urn:mavedb:00000044-b-2#2298,NA,NA,p.Asn58Lys,-0.24,-0.26,2,N388K +urn:mavedb:00000044-b-2#2301,NA,NA,p.Asn58Met,-0.61,-0.51,1,N388M +urn:mavedb:00000044-b-2#2302,NA,NA,p.Asn58Met,-0.4,-0.51,2,N388M +urn:mavedb:00000044-b-2#2289,NA,NA,p.Asn58Phe,-1.34,-1.27,1,N388F +urn:mavedb:00000044-b-2#2290,NA,NA,p.Asn58Phe,-1.2,-1.27,2,N388F +urn:mavedb:00000044-b-2#2303,NA,NA,p.Asn58Pro,-0.15,-0.15,1,N388P +urn:mavedb:00000044-b-2#2304,NA,NA,p.Asn58Pro,-0.15,-0.15,2,N388P +urn:mavedb:00000044-b-2#2309,NA,NA,p.Asn58Ser,-0.28,-0.27,1,N388S +urn:mavedb:00000044-b-2#2310,NA,NA,p.Asn58Ser,-0.27,-0.27,2,N388S +urn:mavedb:00000044-b-2#2311,NA,NA,p.Asn58Thr,-0.47,-0.52,1,N388T +urn:mavedb:00000044-b-2#2312,NA,NA,p.Asn58Thr,-0.56,-0.52,2,N388T +urn:mavedb:00000044-b-2#2315,NA,NA,p.Asn58Trp,-1.42,-1.33,1,N388W +urn:mavedb:00000044-b-2#2316,NA,NA,p.Asn58Trp,-1.24,-1.33,2,N388W +urn:mavedb:00000044-b-2#2317,NA,NA,p.Asn58Tyr,-1.16,-1.27,1,N388Y +urn:mavedb:00000044-b-2#2318,NA,NA,p.Asn58Tyr,-1.38,-1.27,2,N388Y +urn:mavedb:00000044-b-2#2313,NA,NA,p.Asn58Val,-1,-0.81,1,N388V +urn:mavedb:00000044-b-2#2314,NA,NA,p.Asn58Val,-0.62,-0.81,2,N388V +urn:mavedb:00000044-b-2#2559,NA,NA,p.Asn64*,-4.62,-4.58,1,N394 +urn:mavedb:00000044-b-2#2560,NA,NA,p.Asn64*,-4.53,-4.58,2,N394 +urn:mavedb:00000044-b-2#2521,NA,NA,p.Asn64Ala,-0.07,-0.01,1,N394A +urn:mavedb:00000044-b-2#2522,NA,NA,p.Asn64Ala,0.05,-0.01,2,N394A +urn:mavedb:00000044-b-2#2547,NA,NA,p.Asn64Arg,-0.43,-0.42,1,N394R +urn:mavedb:00000044-b-2#2548,NA,NA,p.Asn64Arg,-0.41,-0.42,2,N394R +urn:mavedb:00000044-b-2#2525,NA,NA,p.Asn64Asp,-0.63,-0.4,1,N394D +urn:mavedb:00000044-b-2#2526,NA,NA,p.Asn64Asp,-0.17,-0.4,2,N394D +urn:mavedb:00000044-b-2#2523,NA,NA,p.Asn64Cys,-0.13,-0.17,1,N394C +urn:mavedb:00000044-b-2#2524,NA,NA,p.Asn64Cys,-0.21,-0.17,2,N394C +urn:mavedb:00000044-b-2#2545,NA,NA,p.Asn64Gln,-0.36,-0.29,1,N394Q +urn:mavedb:00000044-b-2#2546,NA,NA,p.Asn64Gln,-0.22,-0.29,2,N394Q +urn:mavedb:00000044-b-2#2527,NA,NA,p.Asn64Glu,-0.05,-0.06,1,N394E +urn:mavedb:00000044-b-2#2528,NA,NA,p.Asn64Glu,-0.08,-0.06,2,N394E +urn:mavedb:00000044-b-2#2531,NA,NA,p.Asn64Gly,-0.53,-0.42,1,N394G +urn:mavedb:00000044-b-2#2532,NA,NA,p.Asn64Gly,-0.32,-0.42,2,N394G +urn:mavedb:00000044-b-2#2533,NA,NA,p.Asn64His,0.04,-0.02,1,N394H +urn:mavedb:00000044-b-2#2534,NA,NA,p.Asn64His,-0.08,-0.02,2,N394H +urn:mavedb:00000044-b-2#2535,NA,NA,p.Asn64Ile,-0.42,-0.43,1,N394I +urn:mavedb:00000044-b-2#2536,NA,NA,p.Asn64Ile,-0.44,-0.43,2,N394I +urn:mavedb:00000044-b-2#2539,NA,NA,p.Asn64Leu,-0.5,-0.48,1,N394L +urn:mavedb:00000044-b-2#2540,NA,NA,p.Asn64Leu,-0.45,-0.48,2,N394L +urn:mavedb:00000044-b-2#2537,NA,NA,p.Asn64Lys,-0.35,-0.37,1,N394K +urn:mavedb:00000044-b-2#2538,NA,NA,p.Asn64Lys,-0.39,-0.37,2,N394K +urn:mavedb:00000044-b-2#2541,NA,NA,p.Asn64Met,-0.41,-0.37,1,N394M +urn:mavedb:00000044-b-2#2542,NA,NA,p.Asn64Met,-0.33,-0.37,2,N394M +urn:mavedb:00000044-b-2#2529,NA,NA,p.Asn64Phe,-0.26,-0.26,1,N394F +urn:mavedb:00000044-b-2#2530,NA,NA,p.Asn64Phe,-0.27,-0.26,2,N394F +urn:mavedb:00000044-b-2#2543,NA,NA,p.Asn64Pro,-0.46,-0.48,1,N394P +urn:mavedb:00000044-b-2#2544,NA,NA,p.Asn64Pro,-0.5,-0.48,2,N394P +urn:mavedb:00000044-b-2#2549,NA,NA,p.Asn64Ser,-0.09,-0.07,1,N394S +urn:mavedb:00000044-b-2#2550,NA,NA,p.Asn64Ser,-0.05,-0.07,2,N394S +urn:mavedb:00000044-b-2#2551,NA,NA,p.Asn64Thr,0.01,0.03,1,N394T +urn:mavedb:00000044-b-2#2552,NA,NA,p.Asn64Thr,0.04,0.03,2,N394T +urn:mavedb:00000044-b-2#2555,NA,NA,p.Asn64Trp,-0.41,-0.42,1,N394W +urn:mavedb:00000044-b-2#2556,NA,NA,p.Asn64Trp,-0.44,-0.42,2,N394W +urn:mavedb:00000044-b-2#2557,NA,NA,p.Asn64Tyr,-0.08,-0.12,1,N394Y +urn:mavedb:00000044-b-2#2558,NA,NA,p.Asn64Tyr,-0.15,-0.12,2,N394Y +urn:mavedb:00000044-b-2#2553,NA,NA,p.Asn64Val,-0.14,-0.17,1,N394V +urn:mavedb:00000044-b-2#2554,NA,NA,p.Asn64Val,-0.2,-0.17,2,N394V +urn:mavedb:00000044-b-2#3679,NA,NA,p.Asn92*,-4.6,-4.58,1,N422 +urn:mavedb:00000044-b-2#3680,NA,NA,p.Asn92*,-4.55,-4.58,2,N422 +urn:mavedb:00000044-b-2#3641,NA,NA,p.Asn92Ala,-2.43,-2.46,1,N422A +urn:mavedb:00000044-b-2#3642,NA,NA,p.Asn92Ala,-2.49,-2.46,2,N422A +urn:mavedb:00000044-b-2#3667,NA,NA,p.Asn92Arg,-2.63,-2.58,1,N422R +urn:mavedb:00000044-b-2#3668,NA,NA,p.Asn92Arg,-2.54,-2.58,2,N422R +urn:mavedb:00000044-b-2#3645,NA,NA,p.Asn92Asp,-2.43,-2.37,1,N422D +urn:mavedb:00000044-b-2#3646,NA,NA,p.Asn92Asp,-2.31,-2.37,2,N422D +urn:mavedb:00000044-b-2#3643,NA,NA,p.Asn92Cys,-2.4,-2.31,1,N422C +urn:mavedb:00000044-b-2#3644,NA,NA,p.Asn92Cys,-2.22,-2.31,2,N422C +urn:mavedb:00000044-b-2#3665,NA,NA,p.Asn92Gln,-2.37,-2.51,1,N422Q +urn:mavedb:00000044-b-2#3666,NA,NA,p.Asn92Gln,-2.65,-2.51,2,N422Q +urn:mavedb:00000044-b-2#3647,NA,NA,p.Asn92Glu,-2.56,-2.52,1,N422E +urn:mavedb:00000044-b-2#3648,NA,NA,p.Asn92Glu,-2.49,-2.52,2,N422E +urn:mavedb:00000044-b-2#3651,NA,NA,p.Asn92Gly,-2.7,-2.56,1,N422G +urn:mavedb:00000044-b-2#3652,NA,NA,p.Asn92Gly,-2.42,-2.56,2,N422G +urn:mavedb:00000044-b-2#3653,NA,NA,p.Asn92His,-2.72,-2.56,1,N422H +urn:mavedb:00000044-b-2#3654,NA,NA,p.Asn92His,-2.39,-2.56,2,N422H +urn:mavedb:00000044-b-2#3655,NA,NA,p.Asn92Ile,-2.37,-2.46,1,N422I +urn:mavedb:00000044-b-2#3656,NA,NA,p.Asn92Ile,-2.56,-2.46,2,N422I +urn:mavedb:00000044-b-2#3659,NA,NA,p.Asn92Leu,-2.5,-2.54,1,N422L +urn:mavedb:00000044-b-2#3660,NA,NA,p.Asn92Leu,-2.57,-2.54,2,N422L +urn:mavedb:00000044-b-2#3657,NA,NA,p.Asn92Lys,-2.62,-2.67,1,N422K +urn:mavedb:00000044-b-2#3658,NA,NA,p.Asn92Lys,-2.72,-2.67,2,N422K +urn:mavedb:00000044-b-2#3661,NA,NA,p.Asn92Met,-2.67,-2.64,1,N422M +urn:mavedb:00000044-b-2#3662,NA,NA,p.Asn92Met,-2.61,-2.64,2,N422M +urn:mavedb:00000044-b-2#3649,NA,NA,p.Asn92Phe,-2.55,-2.64,1,N422F 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+urn:mavedb:00000044-b-2#7765,NA,NA,p.Cys195Glu,NA,-2.75,1,C525E +urn:mavedb:00000044-b-2#7766,NA,NA,p.Cys195Glu,-2.75,-2.75,2,C525E +urn:mavedb:00000044-b-2#7769,NA,NA,p.Cys195Gly,0.53,-0.04,1,C525G +urn:mavedb:00000044-b-2#7770,NA,NA,p.Cys195Gly,-0.61,-0.04,2,C525G +urn:mavedb:00000044-b-2#7771,NA,NA,p.Cys195His,-0.89,-1.39,1,C525H +urn:mavedb:00000044-b-2#7772,NA,NA,p.Cys195His,-1.88,-1.39,2,C525H +urn:mavedb:00000044-b-2#7773,NA,NA,p.Cys195Ile,-0.15,-0.17,1,C525I +urn:mavedb:00000044-b-2#7774,NA,NA,p.Cys195Ile,-0.19,-0.17,2,C525I +urn:mavedb:00000044-b-2#7777,NA,NA,p.Cys195Leu,-0.46,-0.33,1,C525L +urn:mavedb:00000044-b-2#7778,NA,NA,p.Cys195Leu,-0.2,-0.33,2,C525L +urn:mavedb:00000044-b-2#7775,NA,NA,p.Cys195Lys,-0.57,-0.83,1,C525K +urn:mavedb:00000044-b-2#7776,NA,NA,p.Cys195Lys,-1.09,-0.83,2,C525K +urn:mavedb:00000044-b-2#7779,NA,NA,p.Cys195Met,-0.08,-0.37,1,C525M +urn:mavedb:00000044-b-2#7780,NA,NA,p.Cys195Met,-0.66,-0.37,2,C525M +urn:mavedb:00000044-b-2#7767,NA,NA,p.Cys195Phe,-0.58,-0.48,1,C525F +urn:mavedb:00000044-b-2#7768,NA,NA,p.Cys195Phe,-0.37,-0.48,2,C525F +urn:mavedb:00000044-b-2#7783,NA,NA,p.Cys195Pro,0.63,-0.2,1,C525P +urn:mavedb:00000044-b-2#7784,NA,NA,p.Cys195Pro,-1.02,-0.2,2,C525P +urn:mavedb:00000044-b-2#7789,NA,NA,p.Cys195Ser,-0.17,-0.17,1,C525S +urn:mavedb:00000044-b-2#7790,NA,NA,p.Cys195Ser,-0.16,-0.17,2,C525S +urn:mavedb:00000044-b-2#7791,NA,NA,p.Cys195Thr,-0.84,-0.58,1,C525T +urn:mavedb:00000044-b-2#7792,NA,NA,p.Cys195Thr,-0.31,-0.58,2,C525T +urn:mavedb:00000044-b-2#7795,NA,NA,p.Cys195Trp,-0.75,-0.87,1,C525W +urn:mavedb:00000044-b-2#7796,NA,NA,p.Cys195Trp,-0.99,-0.87,2,C525W +urn:mavedb:00000044-b-2#7797,NA,NA,p.Cys195Tyr,-0.14,-0.18,1,C525Y +urn:mavedb:00000044-b-2#7798,NA,NA,p.Cys195Tyr,-0.21,-0.18,2,C525Y +urn:mavedb:00000044-b-2#7793,NA,NA,p.Cys195Val,-0.75,-1.79,1,C525V +urn:mavedb:00000044-b-2#7794,NA,NA,p.Cys195Val,-2.82,-1.79,2,C525V +urn:mavedb:00000044-b-2#1239,NA,NA,p.Cys31*,-4.51,-4.52,1,C361 +urn:mavedb:00000044-b-2#1240,NA,NA,p.Cys31*,-4.53,-4.52,2,C361 +urn:mavedb:00000044-b-2#1201,NA,NA,p.Cys31Ala,-1.03,-1.04,1,C361A +urn:mavedb:00000044-b-2#1202,NA,NA,p.Cys31Ala,-1.04,-1.04,2,C361A +urn:mavedb:00000044-b-2#1227,NA,NA,p.Cys31Arg,-1.44,-1.37,1,C361R +urn:mavedb:00000044-b-2#1228,NA,NA,p.Cys31Arg,-1.29,-1.37,2,C361R +urn:mavedb:00000044-b-2#1221,NA,NA,p.Cys31Asn,-0.9,-0.96,1,C361N +urn:mavedb:00000044-b-2#1222,NA,NA,p.Cys31Asn,-1.02,-0.96,2,C361N +urn:mavedb:00000044-b-2#1203,NA,NA,p.Cys31Asp,-0.4,-0.65,1,C361D +urn:mavedb:00000044-b-2#1204,NA,NA,p.Cys31Asp,-0.91,-0.65,2,C361D +urn:mavedb:00000044-b-2#1225,NA,NA,p.Cys31Gln,-0.98,-1.01,1,C361Q +urn:mavedb:00000044-b-2#1226,NA,NA,p.Cys31Gln,-1.05,-1.01,2,C361Q +urn:mavedb:00000044-b-2#1205,NA,NA,p.Cys31Glu,-1.02,-0.93,1,C361E +urn:mavedb:00000044-b-2#1206,NA,NA,p.Cys31Glu,-0.84,-0.93,2,C361E +urn:mavedb:00000044-b-2#1209,NA,NA,p.Cys31Gly,-1.28,-1.35,1,C361G +urn:mavedb:00000044-b-2#1210,NA,NA,p.Cys31Gly,-1.42,-1.35,2,C361G +urn:mavedb:00000044-b-2#1211,NA,NA,p.Cys31His,-1.3,-1.39,1,C361H +urn:mavedb:00000044-b-2#1212,NA,NA,p.Cys31His,-1.48,-1.39,2,C361H +urn:mavedb:00000044-b-2#1213,NA,NA,p.Cys31Ile,-1.07,-1.04,1,C361I +urn:mavedb:00000044-b-2#1214,NA,NA,p.Cys31Ile,-1,-1.04,2,C361I +urn:mavedb:00000044-b-2#1217,NA,NA,p.Cys31Leu,-1.25,-1.23,1,C361L +urn:mavedb:00000044-b-2#1218,NA,NA,p.Cys31Leu,-1.22,-1.23,2,C361L +urn:mavedb:00000044-b-2#1215,NA,NA,p.Cys31Lys,-1.11,-1.07,1,C361K +urn:mavedb:00000044-b-2#1216,NA,NA,p.Cys31Lys,-1.04,-1.07,2,C361K +urn:mavedb:00000044-b-2#1219,NA,NA,p.Cys31Met,-1.4,-1.31,1,C361M +urn:mavedb:00000044-b-2#1220,NA,NA,p.Cys31Met,-1.21,-1.31,2,C361M +urn:mavedb:00000044-b-2#1207,NA,NA,p.Cys31Phe,-1,-1.07,1,C361F +urn:mavedb:00000044-b-2#1208,NA,NA,p.Cys31Phe,-1.13,-1.07,2,C361F +urn:mavedb:00000044-b-2#1223,NA,NA,p.Cys31Pro,-0.26,-0.36,1,C361P +urn:mavedb:00000044-b-2#1224,NA,NA,p.Cys31Pro,-0.47,-0.36,2,C361P +urn:mavedb:00000044-b-2#1229,NA,NA,p.Cys31Ser,-1.21,-1.1,1,C361S +urn:mavedb:00000044-b-2#1230,NA,NA,p.Cys31Ser,-1,-1.1,2,C361S +urn:mavedb:00000044-b-2#1231,NA,NA,p.Cys31Thr,-1.19,-1.08,1,C361T +urn:mavedb:00000044-b-2#1232,NA,NA,p.Cys31Thr,-0.96,-1.08,2,C361T +urn:mavedb:00000044-b-2#1235,NA,NA,p.Cys31Trp,-1.19,-1.22,1,C361W +urn:mavedb:00000044-b-2#1236,NA,NA,p.Cys31Trp,-1.26,-1.22,2,C361W +urn:mavedb:00000044-b-2#1237,NA,NA,p.Cys31Tyr,-1.59,-1.71,1,C361Y +urn:mavedb:00000044-b-2#1238,NA,NA,p.Cys31Tyr,-1.83,-1.71,2,C361Y +urn:mavedb:00000044-b-2#1233,NA,NA,p.Cys31Val,-1.17,-1.1,1,C361V +urn:mavedb:00000044-b-2#1234,NA,NA,p.Cys31Val,-1.02,-1.1,2,C361V +urn:mavedb:00000044-b-2#1959,NA,NA,p.Cys49*,-4.64,-4.56,1,C379 +urn:mavedb:00000044-b-2#1960,NA,NA,p.Cys49*,-4.47,-4.56,2,C379 +urn:mavedb:00000044-b-2#1921,NA,NA,p.Cys49Ala,-3.14,-3.03,1,C379A +urn:mavedb:00000044-b-2#1922,NA,NA,p.Cys49Ala,-2.92,-3.03,2,C379A +urn:mavedb:00000044-b-2#1947,NA,NA,p.Cys49Arg,-3.03,-2.97,1,C379R +urn:mavedb:00000044-b-2#1948,NA,NA,p.Cys49Arg,-2.91,-2.97,2,C379R +urn:mavedb:00000044-b-2#1941,NA,NA,p.Cys49Asn,-3,-2.95,1,C379N +urn:mavedb:00000044-b-2#1942,NA,NA,p.Cys49Asn,-2.91,-2.95,2,C379N +urn:mavedb:00000044-b-2#1923,NA,NA,p.Cys49Asp,-2.89,-2.87,1,C379D +urn:mavedb:00000044-b-2#1924,NA,NA,p.Cys49Asp,-2.85,-2.87,2,C379D +urn:mavedb:00000044-b-2#1945,NA,NA,p.Cys49Gln,-2.92,-2.85,1,C379Q +urn:mavedb:00000044-b-2#1946,NA,NA,p.Cys49Gln,-2.79,-2.85,2,C379Q +urn:mavedb:00000044-b-2#1925,NA,NA,p.Cys49Glu,-3.1,-3.02,1,C379E +urn:mavedb:00000044-b-2#1926,NA,NA,p.Cys49Glu,-2.95,-3.02,2,C379E +urn:mavedb:00000044-b-2#1929,NA,NA,p.Cys49Gly,-3.01,-2.96,1,C379G +urn:mavedb:00000044-b-2#1930,NA,NA,p.Cys49Gly,-2.91,-2.96,2,C379G +urn:mavedb:00000044-b-2#1931,NA,NA,p.Cys49His,-2.99,-2.96,1,C379H +urn:mavedb:00000044-b-2#1932,NA,NA,p.Cys49His,-2.93,-2.96,2,C379H +urn:mavedb:00000044-b-2#1933,NA,NA,p.Cys49Ile,-3,-2.81,1,C379I +urn:mavedb:00000044-b-2#1934,NA,NA,p.Cys49Ile,-2.62,-2.81,2,C379I +urn:mavedb:00000044-b-2#1937,NA,NA,p.Cys49Leu,-2.64,-2.61,1,C379L +urn:mavedb:00000044-b-2#1938,NA,NA,p.Cys49Leu,-2.58,-2.61,2,C379L +urn:mavedb:00000044-b-2#1935,NA,NA,p.Cys49Lys,-3.13,-3.02,1,C379K +urn:mavedb:00000044-b-2#1936,NA,NA,p.Cys49Lys,-2.9,-3.02,2,C379K +urn:mavedb:00000044-b-2#1939,NA,NA,p.Cys49Met,-2.92,-2.85,1,C379M +urn:mavedb:00000044-b-2#1940,NA,NA,p.Cys49Met,-2.78,-2.85,2,C379M +urn:mavedb:00000044-b-2#1927,NA,NA,p.Cys49Phe,-2.92,-2.56,1,C379F +urn:mavedb:00000044-b-2#1928,NA,NA,p.Cys49Phe,-2.2,-2.56,2,C379F +urn:mavedb:00000044-b-2#1943,NA,NA,p.Cys49Pro,-2.96,-2.87,1,C379P +urn:mavedb:00000044-b-2#1944,NA,NA,p.Cys49Pro,-2.78,-2.87,2,C379P +urn:mavedb:00000044-b-2#1949,NA,NA,p.Cys49Ser,-3,-2.94,1,C379S +urn:mavedb:00000044-b-2#1950,NA,NA,p.Cys49Ser,-2.89,-2.94,2,C379S +urn:mavedb:00000044-b-2#1951,NA,NA,p.Cys49Thr,-3.05,-2.93,1,C379T +urn:mavedb:00000044-b-2#1952,NA,NA,p.Cys49Thr,-2.82,-2.93,2,C379T +urn:mavedb:00000044-b-2#1955,NA,NA,p.Cys49Trp,-1.73,-1.85,1,C379W +urn:mavedb:00000044-b-2#1956,NA,NA,p.Cys49Trp,-1.97,-1.85,2,C379W +urn:mavedb:00000044-b-2#1957,NA,NA,p.Cys49Tyr,-3.01,-2.95,1,C379Y +urn:mavedb:00000044-b-2#1958,NA,NA,p.Cys49Tyr,-2.88,-2.95,2,C379Y +urn:mavedb:00000044-b-2#1953,NA,NA,p.Cys49Val,-2.57,-2.56,1,C379V +urn:mavedb:00000044-b-2#1954,NA,NA,p.Cys49Val,-2.55,-2.56,2,C379V +urn:mavedb:00000044-b-2#239,NA,NA,p.Cys6*,-4.68,-4.64,1,C336 +urn:mavedb:00000044-b-2#240,NA,NA,p.Cys6*,-4.6,-4.64,2,C336 +urn:mavedb:00000044-b-2#2439,NA,NA,p.Cys61*,-4.59,-4.56,1,C391 +urn:mavedb:00000044-b-2#2440,NA,NA,p.Cys61*,-4.52,-4.56,2,C391 +urn:mavedb:00000044-b-2#2401,NA,NA,p.Cys61Ala,-0.13,-0.12,1,C391A +urn:mavedb:00000044-b-2#2402,NA,NA,p.Cys61Ala,-0.11,-0.12,2,C391A +urn:mavedb:00000044-b-2#2427,NA,NA,p.Cys61Arg,-0.1,-0.07,1,C391R +urn:mavedb:00000044-b-2#2428,NA,NA,p.Cys61Arg,-0.04,-0.07,2,C391R +urn:mavedb:00000044-b-2#2421,NA,NA,p.Cys61Asn,0.05,0.2,1,C391N +urn:mavedb:00000044-b-2#2422,NA,NA,p.Cys61Asn,0.34,0.2,2,C391N +urn:mavedb:00000044-b-2#2403,NA,NA,p.Cys61Asp,-0.14,-0.16,1,C391D +urn:mavedb:00000044-b-2#2404,NA,NA,p.Cys61Asp,-0.18,-0.16,2,C391D +urn:mavedb:00000044-b-2#2425,NA,NA,p.Cys61Gln,-0.04,-0.01,1,C391Q +urn:mavedb:00000044-b-2#2426,NA,NA,p.Cys61Gln,0.02,-0.01,2,C391Q +urn:mavedb:00000044-b-2#2405,NA,NA,p.Cys61Glu,-0.06,-0.01,1,C391E +urn:mavedb:00000044-b-2#2406,NA,NA,p.Cys61Glu,0.04,-0.01,2,C391E +urn:mavedb:00000044-b-2#2409,NA,NA,p.Cys61Gly,-0.49,-0.57,1,C391G +urn:mavedb:00000044-b-2#2410,NA,NA,p.Cys61Gly,-0.65,-0.57,2,C391G +urn:mavedb:00000044-b-2#2411,NA,NA,p.Cys61His,-0.11,-0.14,1,C391H +urn:mavedb:00000044-b-2#2412,NA,NA,p.Cys61His,-0.18,-0.14,2,C391H +urn:mavedb:00000044-b-2#2413,NA,NA,p.Cys61Ile,-0.28,-0.3,1,C391I +urn:mavedb:00000044-b-2#2414,NA,NA,p.Cys61Ile,-0.32,-0.3,2,C391I +urn:mavedb:00000044-b-2#2417,NA,NA,p.Cys61Leu,-0.4,-0.39,1,C391L +urn:mavedb:00000044-b-2#2418,NA,NA,p.Cys61Leu,-0.38,-0.39,2,C391L +urn:mavedb:00000044-b-2#2415,NA,NA,p.Cys61Lys,-0.03,-0.03,1,C391K +urn:mavedb:00000044-b-2#2416,NA,NA,p.Cys61Lys,-0.03,-0.03,2,C391K +urn:mavedb:00000044-b-2#2419,NA,NA,p.Cys61Met,-0.35,-0.32,1,C391M +urn:mavedb:00000044-b-2#2420,NA,NA,p.Cys61Met,-0.29,-0.32,2,C391M +urn:mavedb:00000044-b-2#2407,NA,NA,p.Cys61Phe,-0.59,-0.56,1,C391F +urn:mavedb:00000044-b-2#2408,NA,NA,p.Cys61Phe,-0.54,-0.56,2,C391F +urn:mavedb:00000044-b-2#2423,NA,NA,p.Cys61Pro,-0.21,-0.28,1,C391P +urn:mavedb:00000044-b-2#2424,NA,NA,p.Cys61Pro,-0.35,-0.28,2,C391P +urn:mavedb:00000044-b-2#2429,NA,NA,p.Cys61Ser,-0.14,-0.15,1,C391S +urn:mavedb:00000044-b-2#2430,NA,NA,p.Cys61Ser,-0.17,-0.15,2,C391S +urn:mavedb:00000044-b-2#2431,NA,NA,p.Cys61Thr,-0.1,-0.14,1,C391T +urn:mavedb:00000044-b-2#2432,NA,NA,p.Cys61Thr,-0.18,-0.14,2,C391T +urn:mavedb:00000044-b-2#2435,NA,NA,p.Cys61Trp,-0.6,-0.59,1,C391W +urn:mavedb:00000044-b-2#2436,NA,NA,p.Cys61Trp,-0.58,-0.59,2,C391W +urn:mavedb:00000044-b-2#2437,NA,NA,p.Cys61Tyr,-0.39,-0.47,1,C391Y +urn:mavedb:00000044-b-2#2438,NA,NA,p.Cys61Tyr,-0.56,-0.47,2,C391Y +urn:mavedb:00000044-b-2#2433,NA,NA,p.Cys61Val,-0.13,-0.13,1,C391V +urn:mavedb:00000044-b-2#2434,NA,NA,p.Cys61Val,-0.14,-0.13,2,C391V +urn:mavedb:00000044-b-2#201,NA,NA,p.Cys6Ala,-1.53,-1.49,1,C336A +urn:mavedb:00000044-b-2#202,NA,NA,p.Cys6Ala,-1.46,-1.49,2,C336A +urn:mavedb:00000044-b-2#227,NA,NA,p.Cys6Arg,-2.24,-2.17,1,C336R +urn:mavedb:00000044-b-2#228,NA,NA,p.Cys6Arg,-2.1,-2.17,2,C336R +urn:mavedb:00000044-b-2#221,NA,NA,p.Cys6Asn,-1.32,-1.35,1,C336N +urn:mavedb:00000044-b-2#222,NA,NA,p.Cys6Asn,-1.38,-1.35,2,C336N +urn:mavedb:00000044-b-2#203,NA,NA,p.Cys6Asp,-1.04,-1.16,1,C336D +urn:mavedb:00000044-b-2#204,NA,NA,p.Cys6Asp,-1.28,-1.16,2,C336D +urn:mavedb:00000044-b-2#225,NA,NA,p.Cys6Gln,-1.57,-1.67,1,C336Q +urn:mavedb:00000044-b-2#226,NA,NA,p.Cys6Gln,-1.77,-1.67,2,C336Q +urn:mavedb:00000044-b-2#205,NA,NA,p.Cys6Glu,-1.44,-1.44,1,C336E +urn:mavedb:00000044-b-2#206,NA,NA,p.Cys6Glu,-1.44,-1.44,2,C336E +urn:mavedb:00000044-b-2#209,NA,NA,p.Cys6Gly,-1.12,-0.96,1,C336G +urn:mavedb:00000044-b-2#210,NA,NA,p.Cys6Gly,-0.79,-0.96,2,C336G +urn:mavedb:00000044-b-2#211,NA,NA,p.Cys6His,-1.36,-1.39,1,C336H +urn:mavedb:00000044-b-2#212,NA,NA,p.Cys6His,-1.43,-1.39,2,C336H +urn:mavedb:00000044-b-2#213,NA,NA,p.Cys6Ile,-1.7,-1.69,1,C336I +urn:mavedb:00000044-b-2#214,NA,NA,p.Cys6Ile,-1.69,-1.69,2,C336I +urn:mavedb:00000044-b-2#217,NA,NA,p.Cys6Leu,-1.69,-1.68,1,C336L +urn:mavedb:00000044-b-2#218,NA,NA,p.Cys6Leu,-1.67,-1.68,2,C336L +urn:mavedb:00000044-b-2#215,NA,NA,p.Cys6Lys,-1.81,-1.93,1,C336K +urn:mavedb:00000044-b-2#216,NA,NA,p.Cys6Lys,-2.04,-1.93,2,C336K +urn:mavedb:00000044-b-2#219,NA,NA,p.Cys6Met,-1.73,-1.77,1,C336M +urn:mavedb:00000044-b-2#220,NA,NA,p.Cys6Met,-1.81,-1.77,2,C336M +urn:mavedb:00000044-b-2#207,NA,NA,p.Cys6Phe,-1.3,-1.28,1,C336F +urn:mavedb:00000044-b-2#208,NA,NA,p.Cys6Phe,-1.26,-1.28,2,C336F +urn:mavedb:00000044-b-2#223,NA,NA,p.Cys6Pro,-1.98,-1.95,1,C336P +urn:mavedb:00000044-b-2#224,NA,NA,p.Cys6Pro,-1.93,-1.95,2,C336P +urn:mavedb:00000044-b-2#229,NA,NA,p.Cys6Ser,-1.29,-1.38,1,C336S +urn:mavedb:00000044-b-2#230,NA,NA,p.Cys6Ser,-1.46,-1.38,2,C336S +urn:mavedb:00000044-b-2#231,NA,NA,p.Cys6Thr,-1.39,-1.31,1,C336T +urn:mavedb:00000044-b-2#232,NA,NA,p.Cys6Thr,-1.22,-1.31,2,C336T +urn:mavedb:00000044-b-2#235,NA,NA,p.Cys6Trp,-1.83,-1.68,1,C336W +urn:mavedb:00000044-b-2#236,NA,NA,p.Cys6Trp,-1.52,-1.68,2,C336W +urn:mavedb:00000044-b-2#237,NA,NA,p.Cys6Tyr,-1.61,-1.6,1,C336Y +urn:mavedb:00000044-b-2#238,NA,NA,p.Cys6Tyr,-1.59,-1.6,2,C336Y +urn:mavedb:00000044-b-2#233,NA,NA,p.Cys6Val,-1.51,-1.51,1,C336V +urn:mavedb:00000044-b-2#234,NA,NA,p.Cys6Val,-1.5,-1.51,2,C336V +urn:mavedb:00000044-b-2#5759,NA,NA,p.Gln144*,-4.64,-4.51,1,Q474 +urn:mavedb:00000044-b-2#5760,NA,NA,p.Gln144*,-4.39,-4.51,2,Q474 +urn:mavedb:00000044-b-2#5721,NA,NA,p.Gln144Ala,-0.11,-0.39,1,Q474A +urn:mavedb:00000044-b-2#5722,NA,NA,p.Gln144Ala,-0.68,-0.39,2,Q474A +urn:mavedb:00000044-b-2#5747,NA,NA,p.Gln144Arg,-0.66,-0.65,1,Q474R +urn:mavedb:00000044-b-2#5748,NA,NA,p.Gln144Arg,-0.64,-0.65,2,Q474R +urn:mavedb:00000044-b-2#5743,NA,NA,p.Gln144Asn,-0.22,-0.18,1,Q474N +urn:mavedb:00000044-b-2#5744,NA,NA,p.Gln144Asn,-0.14,-0.18,2,Q474N +urn:mavedb:00000044-b-2#5725,NA,NA,p.Gln144Asp,-0.42,-0.38,1,Q474D +urn:mavedb:00000044-b-2#5726,NA,NA,p.Gln144Asp,-0.35,-0.38,2,Q474D +urn:mavedb:00000044-b-2#5723,NA,NA,p.Gln144Cys,-0.97,-1.1,1,Q474C +urn:mavedb:00000044-b-2#5724,NA,NA,p.Gln144Cys,-1.23,-1.1,2,Q474C +urn:mavedb:00000044-b-2#5727,NA,NA,p.Gln144Glu,-0.19,-0.24,1,Q474E +urn:mavedb:00000044-b-2#5728,NA,NA,p.Gln144Glu,-0.28,-0.24,2,Q474E +urn:mavedb:00000044-b-2#5731,NA,NA,p.Gln144Gly,-0.53,-0.53,1,Q474G +urn:mavedb:00000044-b-2#5732,NA,NA,p.Gln144Gly,-0.54,-0.53,2,Q474G +urn:mavedb:00000044-b-2#5733,NA,NA,p.Gln144His,-0.57,-0.55,1,Q474H +urn:mavedb:00000044-b-2#5734,NA,NA,p.Gln144His,-0.52,-0.55,2,Q474H +urn:mavedb:00000044-b-2#5735,NA,NA,p.Gln144Ile,-1.4,-1.35,1,Q474I +urn:mavedb:00000044-b-2#5736,NA,NA,p.Gln144Ile,-1.3,-1.35,2,Q474I +urn:mavedb:00000044-b-2#5739,NA,NA,p.Gln144Leu,-1.71,-1.69,1,Q474L +urn:mavedb:00000044-b-2#5740,NA,NA,p.Gln144Leu,-1.68,-1.69,2,Q474L +urn:mavedb:00000044-b-2#5737,NA,NA,p.Gln144Lys,-0.65,-0.57,1,Q474K +urn:mavedb:00000044-b-2#5738,NA,NA,p.Gln144Lys,-0.48,-0.57,2,Q474K +urn:mavedb:00000044-b-2#5741,NA,NA,p.Gln144Met,-0.69,-0.68,1,Q474M +urn:mavedb:00000044-b-2#5742,NA,NA,p.Gln144Met,-0.67,-0.68,2,Q474M +urn:mavedb:00000044-b-2#5729,NA,NA,p.Gln144Phe,-1.53,-1.5,1,Q474F +urn:mavedb:00000044-b-2#5730,NA,NA,p.Gln144Phe,-1.48,-1.5,2,Q474F +urn:mavedb:00000044-b-2#5745,NA,NA,p.Gln144Pro,-0.34,-0.33,1,Q474P +urn:mavedb:00000044-b-2#5746,NA,NA,p.Gln144Pro,-0.32,-0.33,2,Q474P +urn:mavedb:00000044-b-2#5749,NA,NA,p.Gln144Ser,-0.26,-0.26,1,Q474S +urn:mavedb:00000044-b-2#5750,NA,NA,p.Gln144Ser,-0.25,-0.26,2,Q474S +urn:mavedb:00000044-b-2#5751,NA,NA,p.Gln144Thr,-0.71,-0.59,1,Q474T +urn:mavedb:00000044-b-2#5752,NA,NA,p.Gln144Thr,-0.46,-0.59,2,Q474T +urn:mavedb:00000044-b-2#5755,NA,NA,p.Gln144Trp,-2.85,-2.03,1,Q474W +urn:mavedb:00000044-b-2#5756,NA,NA,p.Gln144Trp,-1.21,-2.03,2,Q474W +urn:mavedb:00000044-b-2#5757,NA,NA,p.Gln144Tyr,-1.53,-1.5,1,Q474Y +urn:mavedb:00000044-b-2#5758,NA,NA,p.Gln144Tyr,-1.47,-1.5,2,Q474Y +urn:mavedb:00000044-b-2#5753,NA,NA,p.Gln144Val,-0.9,-0.97,1,Q474V +urn:mavedb:00000044-b-2#5754,NA,NA,p.Gln144Val,-1.04,-0.97,2,Q474V +urn:mavedb:00000044-b-2#6519,NA,NA,p.Gln163*,-4.58,-4.54,1,Q493 +urn:mavedb:00000044-b-2#6520,NA,NA,p.Gln163*,-4.5,-4.54,2,Q493 +urn:mavedb:00000044-b-2#6481,NA,NA,p.Gln163Ala,0.09,0.06,1,Q493A +urn:mavedb:00000044-b-2#6482,NA,NA,p.Gln163Ala,0.02,0.06,2,Q493A +urn:mavedb:00000044-b-2#6507,NA,NA,p.Gln163Arg,-0.09,-0.06,1,Q493R +urn:mavedb:00000044-b-2#6508,NA,NA,p.Gln163Arg,-0.02,-0.06,2,Q493R +urn:mavedb:00000044-b-2#6503,NA,NA,p.Gln163Asn,-0.27,-0.23,1,Q493N +urn:mavedb:00000044-b-2#6504,NA,NA,p.Gln163Asn,-0.2,-0.23,2,Q493N +urn:mavedb:00000044-b-2#6485,NA,NA,p.Gln163Asp,-0.07,-0.1,1,Q493D +urn:mavedb:00000044-b-2#6486,NA,NA,p.Gln163Asp,-0.12,-0.1,2,Q493D +urn:mavedb:00000044-b-2#6483,NA,NA,p.Gln163Cys,-0.62,-0.46,1,Q493C +urn:mavedb:00000044-b-2#6484,NA,NA,p.Gln163Cys,-0.31,-0.46,2,Q493C +urn:mavedb:00000044-b-2#6487,NA,NA,p.Gln163Glu,0.01,-0.02,1,Q493E +urn:mavedb:00000044-b-2#6488,NA,NA,p.Gln163Glu,-0.05,-0.02,2,Q493E +urn:mavedb:00000044-b-2#6491,NA,NA,p.Gln163Gly,-0.08,-0.08,1,Q493G +urn:mavedb:00000044-b-2#6492,NA,NA,p.Gln163Gly,-0.08,-0.08,2,Q493G +urn:mavedb:00000044-b-2#6493,NA,NA,p.Gln163His,-0.19,-0.17,1,Q493H +urn:mavedb:00000044-b-2#6494,NA,NA,p.Gln163His,-0.16,-0.17,2,Q493H +urn:mavedb:00000044-b-2#6495,NA,NA,p.Gln163Ile,-0.43,-0.39,1,Q493I +urn:mavedb:00000044-b-2#6496,NA,NA,p.Gln163Ile,-0.35,-0.39,2,Q493I +urn:mavedb:00000044-b-2#6499,NA,NA,p.Gln163Leu,-0.42,-0.44,1,Q493L +urn:mavedb:00000044-b-2#6500,NA,NA,p.Gln163Leu,-0.47,-0.44,2,Q493L +urn:mavedb:00000044-b-2#6497,NA,NA,p.Gln163Lys,0.05,0.03,1,Q493K +urn:mavedb:00000044-b-2#6498,NA,NA,p.Gln163Lys,0.01,0.03,2,Q493K +urn:mavedb:00000044-b-2#6501,NA,NA,p.Gln163Met,-0.1,-0.07,1,Q493M +urn:mavedb:00000044-b-2#6502,NA,NA,p.Gln163Met,-0.05,-0.07,2,Q493M +urn:mavedb:00000044-b-2#6489,NA,NA,p.Gln163Phe,-0.81,-0.74,1,Q493F +urn:mavedb:00000044-b-2#6490,NA,NA,p.Gln163Phe,-0.66,-0.74,2,Q493F +urn:mavedb:00000044-b-2#6505,NA,NA,p.Gln163Pro,-2.22,-2.1,1,Q493P +urn:mavedb:00000044-b-2#6506,NA,NA,p.Gln163Pro,-1.98,-2.1,2,Q493P +urn:mavedb:00000044-b-2#6509,NA,NA,p.Gln163Ser,-0.04,-0.05,1,Q493S +urn:mavedb:00000044-b-2#6510,NA,NA,p.Gln163Ser,-0.06,-0.05,2,Q493S +urn:mavedb:00000044-b-2#6511,NA,NA,p.Gln163Thr,-0.09,-0.09,1,Q493T +urn:mavedb:00000044-b-2#6512,NA,NA,p.Gln163Thr,-0.1,-0.09,2,Q493T +urn:mavedb:00000044-b-2#6515,NA,NA,p.Gln163Trp,-0.63,-0.76,1,Q493W +urn:mavedb:00000044-b-2#6516,NA,NA,p.Gln163Trp,-0.89,-0.76,2,Q493W +urn:mavedb:00000044-b-2#6517,NA,NA,p.Gln163Tyr,-1.25,-0.97,1,Q493Y +urn:mavedb:00000044-b-2#6518,NA,NA,p.Gln163Tyr,-0.68,-0.97,2,Q493Y +urn:mavedb:00000044-b-2#6513,NA,NA,p.Gln163Val,-0.09,-0.1,1,Q493V +urn:mavedb:00000044-b-2#6514,NA,NA,p.Gln163Val,-0.11,-0.1,2,Q493V +urn:mavedb:00000044-b-2#6719,NA,NA,p.Gln168*,-4.6,-4.56,1,Q498 +urn:mavedb:00000044-b-2#6720,NA,NA,p.Gln168*,-4.52,-4.56,2,Q498 +urn:mavedb:00000044-b-2#6681,NA,NA,p.Gln168Ala,-0.05,0.05,1,Q498A +urn:mavedb:00000044-b-2#6682,NA,NA,p.Gln168Ala,0.15,0.05,2,Q498A +urn:mavedb:00000044-b-2#6707,NA,NA,p.Gln168Arg,-0.03,-0.1,1,Q498R +urn:mavedb:00000044-b-2#6708,NA,NA,p.Gln168Arg,-0.18,-0.1,2,Q498R +urn:mavedb:00000044-b-2#6703,NA,NA,p.Gln168Asn,-0.09,-0.1,1,Q498N +urn:mavedb:00000044-b-2#6704,NA,NA,p.Gln168Asn,-0.11,-0.1,2,Q498N +urn:mavedb:00000044-b-2#6685,NA,NA,p.Gln168Asp,0.57,0.45,1,Q498D +urn:mavedb:00000044-b-2#6686,NA,NA,p.Gln168Asp,0.33,0.45,2,Q498D +urn:mavedb:00000044-b-2#6683,NA,NA,p.Gln168Cys,-0.55,-0.44,1,Q498C +urn:mavedb:00000044-b-2#6684,NA,NA,p.Gln168Cys,-0.32,-0.44,2,Q498C +urn:mavedb:00000044-b-2#6687,NA,NA,p.Gln168Glu,-0.05,-0.06,1,Q498E +urn:mavedb:00000044-b-2#6688,NA,NA,p.Gln168Glu,-0.07,-0.06,2,Q498E +urn:mavedb:00000044-b-2#6691,NA,NA,p.Gln168Gly,-0.1,-0.09,1,Q498G +urn:mavedb:00000044-b-2#6692,NA,NA,p.Gln168Gly,-0.07,-0.09,2,Q498G +urn:mavedb:00000044-b-2#6693,NA,NA,p.Gln168His,0.15,0.16,1,Q498H +urn:mavedb:00000044-b-2#6694,NA,NA,p.Gln168His,0.16,0.16,2,Q498H +urn:mavedb:00000044-b-2#6695,NA,NA,p.Gln168Ile,-0.06,-0.12,1,Q498I +urn:mavedb:00000044-b-2#6696,NA,NA,p.Gln168Ile,-0.18,-0.12,2,Q498I +urn:mavedb:00000044-b-2#6699,NA,NA,p.Gln168Leu,-0.19,-0.14,1,Q498L +urn:mavedb:00000044-b-2#6700,NA,NA,p.Gln168Leu,-0.1,-0.14,2,Q498L 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+urn:mavedb:00000044-b-2#3014,NA,NA,p.Glu76Ile,-2.57,-2.72,2,E406I +urn:mavedb:00000044-b-2#3017,NA,NA,p.Glu76Leu,-2.89,-2.51,1,E406L +urn:mavedb:00000044-b-2#3018,NA,NA,p.Glu76Leu,-2.13,-2.51,2,E406L +urn:mavedb:00000044-b-2#3015,NA,NA,p.Glu76Lys,-2.53,-2.34,1,E406K +urn:mavedb:00000044-b-2#3016,NA,NA,p.Glu76Lys,-2.14,-2.34,2,E406K +urn:mavedb:00000044-b-2#3019,NA,NA,p.Glu76Met,-1.22,-1.2,1,E406M +urn:mavedb:00000044-b-2#3020,NA,NA,p.Glu76Met,-1.19,-1.2,2,E406M +urn:mavedb:00000044-b-2#3007,NA,NA,p.Glu76Phe,-2.04,-2.11,1,E406F +urn:mavedb:00000044-b-2#3008,NA,NA,p.Glu76Phe,-2.17,-2.11,2,E406F +urn:mavedb:00000044-b-2#3023,NA,NA,p.Glu76Pro,-2.51,-2.68,1,E406P +urn:mavedb:00000044-b-2#3024,NA,NA,p.Glu76Pro,-2.85,-2.68,2,E406P +urn:mavedb:00000044-b-2#3029,NA,NA,p.Glu76Ser,-2.33,-2.54,1,E406S +urn:mavedb:00000044-b-2#3030,NA,NA,p.Glu76Ser,-2.75,-2.54,2,E406S +urn:mavedb:00000044-b-2#3031,NA,NA,p.Glu76Thr,-2.46,-2.39,1,E406T +urn:mavedb:00000044-b-2#3032,NA,NA,p.Glu76Thr,-2.32,-2.39,2,E406T +urn:mavedb:00000044-b-2#3035,NA,NA,p.Glu76Trp,-0.32,-0.25,1,E406W +urn:mavedb:00000044-b-2#3036,NA,NA,p.Glu76Trp,-0.18,-0.25,2,E406W +urn:mavedb:00000044-b-2#3037,NA,NA,p.Glu76Tyr,-2.33,-2.35,1,E406Y +urn:mavedb:00000044-b-2#3038,NA,NA,p.Glu76Tyr,-2.38,-2.35,2,E406Y +urn:mavedb:00000044-b-2#3033,NA,NA,p.Glu76Val,-2.4,-2.41,1,E406V +urn:mavedb:00000044-b-2#3034,NA,NA,p.Glu76Val,-2.42,-2.41,2,E406V +urn:mavedb:00000044-b-2#4039,NA,NA,p.Gly101*,-4.56,-4.55,1,G431 +urn:mavedb:00000044-b-2#4040,NA,NA,p.Gly101*,-4.54,-4.55,2,G431 +urn:mavedb:00000044-b-2#4001,NA,NA,p.Gly101Ala,-2.75,-2.75,1,G431A +urn:mavedb:00000044-b-2#4002,NA,NA,p.Gly101Ala,-2.75,-2.75,2,G431A +urn:mavedb:00000044-b-2#4027,NA,NA,p.Gly101Arg,-2.99,-2.95,1,G431R +urn:mavedb:00000044-b-2#4028,NA,NA,p.Gly101Arg,-2.92,-2.95,2,G431R +urn:mavedb:00000044-b-2#4021,NA,NA,p.Gly101Asn,-2.98,-2.93,1,G431N +urn:mavedb:00000044-b-2#4022,NA,NA,p.Gly101Asn,-2.89,-2.93,2,G431N +urn:mavedb:00000044-b-2#4005,NA,NA,p.Gly101Asp,-2.99,-2.94,1,G431D +urn:mavedb:00000044-b-2#4006,NA,NA,p.Gly101Asp,-2.9,-2.94,2,G431D +urn:mavedb:00000044-b-2#4003,NA,NA,p.Gly101Cys,-2.74,-2.65,1,G431C +urn:mavedb:00000044-b-2#4004,NA,NA,p.Gly101Cys,-2.56,-2.65,2,G431C +urn:mavedb:00000044-b-2#4025,NA,NA,p.Gly101Gln,-2.97,-2.91,1,G431Q +urn:mavedb:00000044-b-2#4026,NA,NA,p.Gly101Gln,-2.85,-2.91,2,G431Q +urn:mavedb:00000044-b-2#4007,NA,NA,p.Gly101Glu,-3.05,-2.96,1,G431E +urn:mavedb:00000044-b-2#4008,NA,NA,p.Gly101Glu,-2.86,-2.96,2,G431E +urn:mavedb:00000044-b-2#4011,NA,NA,p.Gly101His,-2.89,-2.86,1,G431H +urn:mavedb:00000044-b-2#4012,NA,NA,p.Gly101His,-2.82,-2.86,2,G431H +urn:mavedb:00000044-b-2#4013,NA,NA,p.Gly101Ile,-2.57,-2.47,1,G431I +urn:mavedb:00000044-b-2#4014,NA,NA,p.Gly101Ile,-2.37,-2.47,2,G431I +urn:mavedb:00000044-b-2#4017,NA,NA,p.Gly101Leu,-2.57,-2.62,1,G431L +urn:mavedb:00000044-b-2#4018,NA,NA,p.Gly101Leu,-2.66,-2.62,2,G431L +urn:mavedb:00000044-b-2#4015,NA,NA,p.Gly101Lys,-3.01,-2.92,1,G431K +urn:mavedb:00000044-b-2#4016,NA,NA,p.Gly101Lys,-2.82,-2.92,2,G431K +urn:mavedb:00000044-b-2#4019,NA,NA,p.Gly101Met,-2.65,-2.7,1,G431M +urn:mavedb:00000044-b-2#4020,NA,NA,p.Gly101Met,-2.75,-2.7,2,G431M +urn:mavedb:00000044-b-2#4009,NA,NA,p.Gly101Phe,-2.32,-2.5,1,G431F +urn:mavedb:00000044-b-2#4010,NA,NA,p.Gly101Phe,-2.68,-2.5,2,G431F +urn:mavedb:00000044-b-2#4023,NA,NA,p.Gly101Pro,-3,-2.91,1,G431P +urn:mavedb:00000044-b-2#4024,NA,NA,p.Gly101Pro,-2.83,-2.91,2,G431P +urn:mavedb:00000044-b-2#4029,NA,NA,p.Gly101Ser,-2.98,-2.95,1,G431S +urn:mavedb:00000044-b-2#4030,NA,NA,p.Gly101Ser,-2.92,-2.95,2,G431S +urn:mavedb:00000044-b-2#4031,NA,NA,p.Gly101Thr,-2.9,-2.86,1,G431T +urn:mavedb:00000044-b-2#4032,NA,NA,p.Gly101Thr,-2.82,-2.86,2,G431T +urn:mavedb:00000044-b-2#4035,NA,NA,p.Gly101Trp,-2.86,-2.79,1,G431W +urn:mavedb:00000044-b-2#4036,NA,NA,p.Gly101Trp,-2.73,-2.79,2,G431W +urn:mavedb:00000044-b-2#4037,NA,NA,p.Gly101Tyr,-2.6,-2.65,1,G431Y +urn:mavedb:00000044-b-2#4038,NA,NA,p.Gly101Tyr,-2.7,-2.65,2,G431Y +urn:mavedb:00000044-b-2#4033,NA,NA,p.Gly101Val,-2.63,-2.61,1,G431V +urn:mavedb:00000044-b-2#4034,NA,NA,p.Gly101Val,-2.6,-2.61,2,G431V +urn:mavedb:00000044-b-2#4639,NA,NA,p.Gly116*,-4.56,-4.55,1,G446 +urn:mavedb:00000044-b-2#4640,NA,NA,p.Gly116*,-4.54,-4.55,2,G446 +urn:mavedb:00000044-b-2#4601,NA,NA,p.Gly116Ala,-0.15,-0.26,1,G446A +urn:mavedb:00000044-b-2#4602,NA,NA,p.Gly116Ala,-0.38,-0.26,2,G446A +urn:mavedb:00000044-b-2#4627,NA,NA,p.Gly116Arg,-0.34,-0.4,1,G446R +urn:mavedb:00000044-b-2#4628,NA,NA,p.Gly116Arg,-0.47,-0.4,2,G446R +urn:mavedb:00000044-b-2#4621,NA,NA,p.Gly116Asn,-0.15,-0.16,1,G446N +urn:mavedb:00000044-b-2#4622,NA,NA,p.Gly116Asn,-0.17,-0.16,2,G446N +urn:mavedb:00000044-b-2#4605,NA,NA,p.Gly116Asp,-0.06,-0.1,1,G446D +urn:mavedb:00000044-b-2#4606,NA,NA,p.Gly116Asp,-0.14,-0.1,2,G446D +urn:mavedb:00000044-b-2#4603,NA,NA,p.Gly116Cys,-1.09,-0.96,1,G446C +urn:mavedb:00000044-b-2#4604,NA,NA,p.Gly116Cys,-0.83,-0.96,2,G446C +urn:mavedb:00000044-b-2#4625,NA,NA,p.Gly116Gln,-0.21,-0.46,1,G446Q +urn:mavedb:00000044-b-2#4626,NA,NA,p.Gly116Gln,-0.72,-0.46,2,G446Q +urn:mavedb:00000044-b-2#4607,NA,NA,p.Gly116Glu,-0.15,-0.12,1,G446E +urn:mavedb:00000044-b-2#4608,NA,NA,p.Gly116Glu,-0.1,-0.12,2,G446E +urn:mavedb:00000044-b-2#4611,NA,NA,p.Gly116His,-0.29,-0.22,1,G446H +urn:mavedb:00000044-b-2#4612,NA,NA,p.Gly116His,-0.15,-0.22,2,G446H +urn:mavedb:00000044-b-2#4613,NA,NA,p.Gly116Ile,-0.58,-0.62,1,G446I +urn:mavedb:00000044-b-2#4614,NA,NA,p.Gly116Ile,-0.66,-0.62,2,G446I +urn:mavedb:00000044-b-2#4617,NA,NA,p.Gly116Leu,-0.52,-0.6,1,G446L +urn:mavedb:00000044-b-2#4618,NA,NA,p.Gly116Leu,-0.68,-0.6,2,G446L +urn:mavedb:00000044-b-2#4615,NA,NA,p.Gly116Lys,-0.67,-0.47,1,G446K +urn:mavedb:00000044-b-2#4616,NA,NA,p.Gly116Lys,-0.27,-0.47,2,G446K +urn:mavedb:00000044-b-2#4619,NA,NA,p.Gly116Met,-0.65,-0.48,1,G446M +urn:mavedb:00000044-b-2#4620,NA,NA,p.Gly116Met,-0.31,-0.48,2,G446M +urn:mavedb:00000044-b-2#4609,NA,NA,p.Gly116Phe,-0.43,-0.49,1,G446F +urn:mavedb:00000044-b-2#4610,NA,NA,p.Gly116Phe,-0.56,-0.49,2,G446F +urn:mavedb:00000044-b-2#4623,NA,NA,p.Gly116Pro,-0.56,-0.56,1,G446P +urn:mavedb:00000044-b-2#4624,NA,NA,p.Gly116Pro,-0.56,-0.56,2,G446P +urn:mavedb:00000044-b-2#4629,NA,NA,p.Gly116Ser,-0.25,-0.4,1,G446S +urn:mavedb:00000044-b-2#4630,NA,NA,p.Gly116Ser,-0.55,-0.4,2,G446S +urn:mavedb:00000044-b-2#4631,NA,NA,p.Gly116Thr,-0.3,-0.35,1,G446T +urn:mavedb:00000044-b-2#4632,NA,NA,p.Gly116Thr,-0.39,-0.35,2,G446T +urn:mavedb:00000044-b-2#4635,NA,NA,p.Gly116Trp,-0.52,-0.72,1,G446W +urn:mavedb:00000044-b-2#4636,NA,NA,p.Gly116Trp,-0.93,-0.72,2,G446W +urn:mavedb:00000044-b-2#4637,NA,NA,p.Gly116Tyr,-0.27,-0.69,1,G446Y +urn:mavedb:00000044-b-2#4638,NA,NA,p.Gly116Tyr,-1.1,-0.69,2,G446Y +urn:mavedb:00000044-b-2#4633,NA,NA,p.Gly116Val,-0.46,-0.48,1,G446V +urn:mavedb:00000044-b-2#4634,NA,NA,p.Gly116Val,-0.5,-0.48,2,G446V +urn:mavedb:00000044-b-2#4679,NA,NA,p.Gly117*,-4.62,-4.59,1,G447 +urn:mavedb:00000044-b-2#4680,NA,NA,p.Gly117*,-4.57,-4.59,2,G447 +urn:mavedb:00000044-b-2#4641,NA,NA,p.Gly117Ala,-0.26,-0.28,1,G447A +urn:mavedb:00000044-b-2#4642,NA,NA,p.Gly117Ala,-0.29,-0.28,2,G447A +urn:mavedb:00000044-b-2#4667,NA,NA,p.Gly117Arg,-0.64,-0.64,1,G447R +urn:mavedb:00000044-b-2#4668,NA,NA,p.Gly117Arg,-0.63,-0.64,2,G447R +urn:mavedb:00000044-b-2#4661,NA,NA,p.Gly117Asn,-0.28,-0.43,1,G447N +urn:mavedb:00000044-b-2#4662,NA,NA,p.Gly117Asn,-0.59,-0.43,2,G447N +urn:mavedb:00000044-b-2#4645,NA,NA,p.Gly117Asp,-0.17,-0.19,1,G447D +urn:mavedb:00000044-b-2#4646,NA,NA,p.Gly117Asp,-0.21,-0.19,2,G447D +urn:mavedb:00000044-b-2#4643,NA,NA,p.Gly117Cys,-0.43,-0.43,1,G447C +urn:mavedb:00000044-b-2#4644,NA,NA,p.Gly117Cys,-0.44,-0.43,2,G447C +urn:mavedb:00000044-b-2#4665,NA,NA,p.Gly117Gln,-0.38,-0.38,1,G447Q +urn:mavedb:00000044-b-2#4666,NA,NA,p.Gly117Gln,-0.37,-0.38,2,G447Q +urn:mavedb:00000044-b-2#4647,NA,NA,p.Gly117Glu,-0.18,-0.2,1,G447E +urn:mavedb:00000044-b-2#4648,NA,NA,p.Gly117Glu,-0.22,-0.2,2,G447E +urn:mavedb:00000044-b-2#4651,NA,NA,p.Gly117His,-0.31,-0.23,1,G447H +urn:mavedb:00000044-b-2#4652,NA,NA,p.Gly117His,-0.14,-0.23,2,G447H +urn:mavedb:00000044-b-2#4653,NA,NA,p.Gly117Ile,-0.49,-0.5,1,G447I +urn:mavedb:00000044-b-2#4654,NA,NA,p.Gly117Ile,-0.51,-0.5,2,G447I +urn:mavedb:00000044-b-2#4657,NA,NA,p.Gly117Leu,-0.5,-0.44,1,G447L +urn:mavedb:00000044-b-2#4658,NA,NA,p.Gly117Leu,-0.39,-0.44,2,G447L +urn:mavedb:00000044-b-2#4655,NA,NA,p.Gly117Lys,-0.28,-0.29,1,G447K +urn:mavedb:00000044-b-2#4656,NA,NA,p.Gly117Lys,-0.3,-0.29,2,G447K +urn:mavedb:00000044-b-2#4659,NA,NA,p.Gly117Met,-0.63,-0.44,1,G447M 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+urn:mavedb:00000044-b-2#7554,NA,NA,p.His189Val,-0.53,-0.37,2,H519V +urn:mavedb:00000044-b-2#4159,NA,NA,p.Ile104*,-4.58,-4.56,1,I434 +urn:mavedb:00000044-b-2#4160,NA,NA,p.Ile104*,-4.54,-4.56,2,I434 +urn:mavedb:00000044-b-2#4121,NA,NA,p.Ile104Ala,-3.06,-1.95,1,I434A +urn:mavedb:00000044-b-2#4122,NA,NA,p.Ile104Ala,-0.84,-1.95,2,I434A +urn:mavedb:00000044-b-2#4147,NA,NA,p.Ile104Arg,-3.19,-3.13,1,I434R +urn:mavedb:00000044-b-2#4148,NA,NA,p.Ile104Arg,-3.07,-3.13,2,I434R +urn:mavedb:00000044-b-2#4141,NA,NA,p.Ile104Asn,-3.26,-3.15,1,I434N +urn:mavedb:00000044-b-2#4142,NA,NA,p.Ile104Asn,-3.03,-3.15,2,I434N +urn:mavedb:00000044-b-2#4125,NA,NA,p.Ile104Asp,-3.22,-3.11,1,I434D +urn:mavedb:00000044-b-2#4126,NA,NA,p.Ile104Asp,-3.01,-3.11,2,I434D +urn:mavedb:00000044-b-2#4123,NA,NA,p.Ile104Cys,-1.09,-1.2,1,I434C +urn:mavedb:00000044-b-2#4124,NA,NA,p.Ile104Cys,-1.32,-1.2,2,I434C +urn:mavedb:00000044-b-2#4145,NA,NA,p.Ile104Gln,-3.21,-3.13,1,I434Q +urn:mavedb:00000044-b-2#4146,NA,NA,p.Ile104Gln,-3.04,-3.13,2,I434Q +urn:mavedb:00000044-b-2#4127,NA,NA,p.Ile104Glu,-3.14,-3.09,1,I434E +urn:mavedb:00000044-b-2#4128,NA,NA,p.Ile104Glu,-3.03,-3.09,2,I434E +urn:mavedb:00000044-b-2#4131,NA,NA,p.Ile104Gly,-2.65,-2.73,1,I434G +urn:mavedb:00000044-b-2#4132,NA,NA,p.Ile104Gly,-2.81,-2.73,2,I434G +urn:mavedb:00000044-b-2#4133,NA,NA,p.Ile104His,-2.97,-2.93,1,I434H +urn:mavedb:00000044-b-2#4134,NA,NA,p.Ile104His,-2.88,-2.93,2,I434H +urn:mavedb:00000044-b-2#4137,NA,NA,p.Ile104Leu,-0.2,-0.21,1,I434L +urn:mavedb:00000044-b-2#4138,NA,NA,p.Ile104Leu,-0.23,-0.21,2,I434L +urn:mavedb:00000044-b-2#4135,NA,NA,p.Ile104Lys,-3.09,-3.04,1,I434K +urn:mavedb:00000044-b-2#4136,NA,NA,p.Ile104Lys,-2.99,-3.04,2,I434K +urn:mavedb:00000044-b-2#4139,NA,NA,p.Ile104Met,-0.21,-0.26,1,I434M +urn:mavedb:00000044-b-2#4140,NA,NA,p.Ile104Met,-0.31,-0.26,2,I434M +urn:mavedb:00000044-b-2#4129,NA,NA,p.Ile104Phe,0.07,0.16,1,I434F +urn:mavedb:00000044-b-2#4130,NA,NA,p.Ile104Phe,0.26,0.16,2,I434F +urn:mavedb:00000044-b-2#4143,NA,NA,p.Ile104Pro,-3.06,-3.03,1,I434P +urn:mavedb:00000044-b-2#4144,NA,NA,p.Ile104Pro,-3,-3.03,2,I434P +urn:mavedb:00000044-b-2#4149,NA,NA,p.Ile104Ser,-2.51,-2.69,1,I434S +urn:mavedb:00000044-b-2#4150,NA,NA,p.Ile104Ser,-2.87,-2.69,2,I434S +urn:mavedb:00000044-b-2#4151,NA,NA,p.Ile104Thr,-1.58,-1.76,1,I434T +urn:mavedb:00000044-b-2#4152,NA,NA,p.Ile104Thr,-1.94,-1.76,2,I434T +urn:mavedb:00000044-b-2#4155,NA,NA,p.Ile104Trp,-0.33,-0.36,1,I434W +urn:mavedb:00000044-b-2#4156,NA,NA,p.Ile104Trp,-0.39,-0.36,2,I434W +urn:mavedb:00000044-b-2#4157,NA,NA,p.Ile104Tyr,-0.48,-0.51,1,I434Y +urn:mavedb:00000044-b-2#4158,NA,NA,p.Ile104Tyr,-0.54,-0.51,2,I434Y +urn:mavedb:00000044-b-2#4153,NA,NA,p.Ile104Val,-0.33,-0.27,1,I434V +urn:mavedb:00000044-b-2#4154,NA,NA,p.Ile104Val,-0.21,-0.27,2,I434V +urn:mavedb:00000044-b-2#5519,NA,NA,p.Ile138*,-4.59,-4.53,1,I468 +urn:mavedb:00000044-b-2#5520,NA,NA,p.Ile138*,-4.47,-4.53,2,I468 +urn:mavedb:00000044-b-2#5481,NA,NA,p.Ile138Ala,-0.34,-0.37,1,I468A +urn:mavedb:00000044-b-2#5482,NA,NA,p.Ile138Ala,-0.41,-0.37,2,I468A +urn:mavedb:00000044-b-2#5507,NA,NA,p.Ile138Arg,-0.45,-0.43,1,I468R +urn:mavedb:00000044-b-2#5508,NA,NA,p.Ile138Arg,-0.41,-0.43,2,I468R +urn:mavedb:00000044-b-2#5501,NA,NA,p.Ile138Asn,-0.01,-0.07,1,I468N +urn:mavedb:00000044-b-2#5502,NA,NA,p.Ile138Asn,-0.12,-0.07,2,I468N +urn:mavedb:00000044-b-2#5485,NA,NA,p.Ile138Asp,-0.17,-0.16,1,I468D +urn:mavedb:00000044-b-2#5486,NA,NA,p.Ile138Asp,-0.16,-0.16,2,I468D +urn:mavedb:00000044-b-2#5483,NA,NA,p.Ile138Cys,-0.16,-0.31,1,I468C +urn:mavedb:00000044-b-2#5484,NA,NA,p.Ile138Cys,-0.45,-0.31,2,I468C +urn:mavedb:00000044-b-2#5505,NA,NA,p.Ile138Gln,-0.39,-0.26,1,I468Q +urn:mavedb:00000044-b-2#5506,NA,NA,p.Ile138Gln,-0.13,-0.26,2,I468Q +urn:mavedb:00000044-b-2#5487,NA,NA,p.Ile138Glu,0.05,0.02,1,I468E +urn:mavedb:00000044-b-2#5488,NA,NA,p.Ile138Glu,-0.01,0.02,2,I468E +urn:mavedb:00000044-b-2#5491,NA,NA,p.Ile138Gly,-0.81,-0.88,1,I468G +urn:mavedb:00000044-b-2#5492,NA,NA,p.Ile138Gly,-0.95,-0.88,2,I468G +urn:mavedb:00000044-b-2#5493,NA,NA,p.Ile138His,-0.85,-0.87,1,I468H +urn:mavedb:00000044-b-2#5494,NA,NA,p.Ile138His,-0.88,-0.87,2,I468H +urn:mavedb:00000044-b-2#5497,NA,NA,p.Ile138Leu,-0.05,-0.03,1,I468L +urn:mavedb:00000044-b-2#5498,NA,NA,p.Ile138Leu,-0.02,-0.03,2,I468L +urn:mavedb:00000044-b-2#5495,NA,NA,p.Ile138Lys,-0.48,-0.5,1,I468K +urn:mavedb:00000044-b-2#5496,NA,NA,p.Ile138Lys,-0.52,-0.5,2,I468K +urn:mavedb:00000044-b-2#5499,NA,NA,p.Ile138Met,-0.14,-0.19,1,I468M +urn:mavedb:00000044-b-2#5500,NA,NA,p.Ile138Met,-0.24,-0.19,2,I468M +urn:mavedb:00000044-b-2#5489,NA,NA,p.Ile138Phe,-1.12,-1.04,1,I468F +urn:mavedb:00000044-b-2#5490,NA,NA,p.Ile138Phe,-0.96,-1.04,2,I468F +urn:mavedb:00000044-b-2#5503,NA,NA,p.Ile138Pro,-0.97,-0.83,1,I468P +urn:mavedb:00000044-b-2#5504,NA,NA,p.Ile138Pro,-0.69,-0.83,2,I468P +urn:mavedb:00000044-b-2#5509,NA,NA,p.Ile138Ser,-0.33,-0.36,1,I468S +urn:mavedb:00000044-b-2#5510,NA,NA,p.Ile138Ser,-0.38,-0.36,2,I468S +urn:mavedb:00000044-b-2#5511,NA,NA,p.Ile138Thr,0.2,0.17,1,I468T +urn:mavedb:00000044-b-2#5512,NA,NA,p.Ile138Thr,0.14,0.17,2,I468T +urn:mavedb:00000044-b-2#5515,NA,NA,p.Ile138Trp,-1,-1.25,1,I468W +urn:mavedb:00000044-b-2#5516,NA,NA,p.Ile138Trp,-1.51,-1.25,2,I468W +urn:mavedb:00000044-b-2#5517,NA,NA,p.Ile138Tyr,-0.81,-0.85,1,I468Y +urn:mavedb:00000044-b-2#5518,NA,NA,p.Ile138Tyr,-0.88,-0.85,2,I468Y +urn:mavedb:00000044-b-2#5513,NA,NA,p.Ile138Val,0.03,0.07,1,I468V +urn:mavedb:00000044-b-2#5514,NA,NA,p.Ile138Val,0.11,0.07,2,I468V +urn:mavedb:00000044-b-2#5679,NA,NA,p.Ile142*,-4.62,-4.56,1,I472 +urn:mavedb:00000044-b-2#5680,NA,NA,p.Ile142*,-4.5,-4.56,2,I472 +urn:mavedb:00000044-b-2#5641,NA,NA,p.Ile142Ala,-0.4,-0.5,1,I472A +urn:mavedb:00000044-b-2#5642,NA,NA,p.Ile142Ala,-0.6,-0.5,2,I472A +urn:mavedb:00000044-b-2#5667,NA,NA,p.Ile142Arg,-1.04,-1.02,1,I472R +urn:mavedb:00000044-b-2#5668,NA,NA,p.Ile142Arg,-0.99,-1.02,2,I472R +urn:mavedb:00000044-b-2#5661,NA,NA,p.Ile142Asn,-0.83,-0.84,1,I472N +urn:mavedb:00000044-b-2#5662,NA,NA,p.Ile142Asn,-0.85,-0.84,2,I472N +urn:mavedb:00000044-b-2#5645,NA,NA,p.Ile142Asp,-1.04,-0.9,1,I472D +urn:mavedb:00000044-b-2#5646,NA,NA,p.Ile142Asp,-0.75,-0.9,2,I472D +urn:mavedb:00000044-b-2#5643,NA,NA,p.Ile142Cys,-0.45,-0.42,1,I472C +urn:mavedb:00000044-b-2#5644,NA,NA,p.Ile142Cys,-0.4,-0.42,2,I472C +urn:mavedb:00000044-b-2#5665,NA,NA,p.Ile142Gln,-0.95,-0.85,1,I472Q +urn:mavedb:00000044-b-2#5666,NA,NA,p.Ile142Gln,-0.74,-0.85,2,I472Q +urn:mavedb:00000044-b-2#5647,NA,NA,p.Ile142Glu,-0.81,-0.93,1,I472E +urn:mavedb:00000044-b-2#5648,NA,NA,p.Ile142Glu,-1.04,-0.93,2,I472E +urn:mavedb:00000044-b-2#5651,NA,NA,p.Ile142Gly,-0.7,-0.77,1,I472G +urn:mavedb:00000044-b-2#5652,NA,NA,p.Ile142Gly,-0.85,-0.77,2,I472G 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+urn:mavedb:00000044-b-2#5671,NA,NA,p.Ile142Thr,-0.29,-0.39,1,I472T +urn:mavedb:00000044-b-2#5672,NA,NA,p.Ile142Thr,-0.49,-0.39,2,I472T +urn:mavedb:00000044-b-2#5675,NA,NA,p.Ile142Trp,-0.44,-0.5,1,I472W +urn:mavedb:00000044-b-2#5676,NA,NA,p.Ile142Trp,-0.56,-0.5,2,I472W +urn:mavedb:00000044-b-2#5677,NA,NA,p.Ile142Tyr,-0.37,-0.43,1,I472Y +urn:mavedb:00000044-b-2#5678,NA,NA,p.Ile142Tyr,-0.49,-0.43,2,I472Y +urn:mavedb:00000044-b-2#5673,NA,NA,p.Ile142Val,-0.14,-0.12,1,I472V +urn:mavedb:00000044-b-2#5674,NA,NA,p.Ile142Val,-0.09,-0.12,2,I472V +urn:mavedb:00000044-b-2#79,NA,NA,p.Ile2*,-4.64,-4.62,1,I332 +urn:mavedb:00000044-b-2#80,NA,NA,p.Ile2*,-4.6,-4.62,2,I332 +urn:mavedb:00000044-b-2#1120,NA,NA,p.Ile28*,-4.52,-4.57,2,I358 +urn:mavedb:00000044-b-2#1119,NA,NA,p.Ile28*,-4.62,-4.57,1,I358 +urn:mavedb:00000044-b-2#1081,NA,NA,p.Ile28Ala,-1.45,-1.44,1,I358A +urn:mavedb:00000044-b-2#1082,NA,NA,p.Ile28Ala,-1.43,-1.44,2,I358A +urn:mavedb:00000044-b-2#1107,NA,NA,p.Ile28Arg,-2.19,-2.15,1,I358R +urn:mavedb:00000044-b-2#1108,NA,NA,p.Ile28Arg,-2.11,-2.15,2,I358R +urn:mavedb:00000044-b-2#1101,NA,NA,p.Ile28Asn,-2.14,-2.04,1,I358N +urn:mavedb:00000044-b-2#1102,NA,NA,p.Ile28Asn,-1.94,-2.04,2,I358N +urn:mavedb:00000044-b-2#1085,NA,NA,p.Ile28Asp,-2.07,-2.13,1,I358D +urn:mavedb:00000044-b-2#1086,NA,NA,p.Ile28Asp,-2.2,-2.13,2,I358D +urn:mavedb:00000044-b-2#1083,NA,NA,p.Ile28Cys,-0.7,-0.91,1,I358C +urn:mavedb:00000044-b-2#1084,NA,NA,p.Ile28Cys,-1.12,-0.91,2,I358C +urn:mavedb:00000044-b-2#1105,NA,NA,p.Ile28Gln,-2.13,-2.05,1,I358Q +urn:mavedb:00000044-b-2#1106,NA,NA,p.Ile28Gln,-1.98,-2.05,2,I358Q +urn:mavedb:00000044-b-2#1087,NA,NA,p.Ile28Glu,-2.01,-1.95,1,I358E +urn:mavedb:00000044-b-2#1088,NA,NA,p.Ile28Glu,-1.9,-1.95,2,I358E +urn:mavedb:00000044-b-2#1091,NA,NA,p.Ile28Gly,-1.85,-1.75,1,I358G +urn:mavedb:00000044-b-2#1092,NA,NA,p.Ile28Gly,-1.66,-1.75,2,I358G +urn:mavedb:00000044-b-2#1093,NA,NA,p.Ile28His,-0.56,-1.06,1,I358H +urn:mavedb:00000044-b-2#1094,NA,NA,p.Ile28His,-1.56,-1.06,2,I358H +urn:mavedb:00000044-b-2#1097,NA,NA,p.Ile28Leu,0.12,0.14,1,I358L +urn:mavedb:00000044-b-2#1098,NA,NA,p.Ile28Leu,0.16,0.14,2,I358L +urn:mavedb:00000044-b-2#1095,NA,NA,p.Ile28Lys,-2.27,-2.22,1,I358K +urn:mavedb:00000044-b-2#1096,NA,NA,p.Ile28Lys,-2.17,-2.22,2,I358K +urn:mavedb:00000044-b-2#1099,NA,NA,p.Ile28Met,0.28,0.26,1,I358M +urn:mavedb:00000044-b-2#1100,NA,NA,p.Ile28Met,0.24,0.26,2,I358M +urn:mavedb:00000044-b-2#1089,NA,NA,p.Ile28Phe,0.62,0.72,1,I358F +urn:mavedb:00000044-b-2#1090,NA,NA,p.Ile28Phe,0.81,0.72,2,I358F +urn:mavedb:00000044-b-2#1103,NA,NA,p.Ile28Pro,-2.06,-2.16,1,I358P +urn:mavedb:00000044-b-2#1104,NA,NA,p.Ile28Pro,-2.26,-2.16,2,I358P +urn:mavedb:00000044-b-2#1109,NA,NA,p.Ile28Ser,-1.9,-1.86,1,I358S +urn:mavedb:00000044-b-2#1110,NA,NA,p.Ile28Ser,-1.82,-1.86,2,I358S +urn:mavedb:00000044-b-2#1111,NA,NA,p.Ile28Thr,-2.03,-1.97,1,I358T +urn:mavedb:00000044-b-2#1112,NA,NA,p.Ile28Thr,-1.91,-1.97,2,I358T +urn:mavedb:00000044-b-2#1115,NA,NA,p.Ile28Trp,0.55,0.41,1,I358W +urn:mavedb:00000044-b-2#1116,NA,NA,p.Ile28Trp,0.27,0.41,2,I358W +urn:mavedb:00000044-b-2#1117,NA,NA,p.Ile28Tyr,0.15,0.1,1,I358Y +urn:mavedb:00000044-b-2#1118,NA,NA,p.Ile28Tyr,0.04,0.1,2,I358Y +urn:mavedb:00000044-b-2#1113,NA,NA,p.Ile28Val,-0.73,-0.59,1,I358V +urn:mavedb:00000044-b-2#1114,NA,NA,p.Ile28Val,-0.44,-0.59,2,I358V +urn:mavedb:00000044-b-2#41,NA,NA,p.Ile2Ala,0.02,0,1,I332A +urn:mavedb:00000044-b-2#42,NA,NA,p.Ile2Ala,-0.02,0,2,I332A +urn:mavedb:00000044-b-2#67,NA,NA,p.Ile2Arg,-0.02,-0.04,1,I332R +urn:mavedb:00000044-b-2#68,NA,NA,p.Ile2Arg,-0.05,-0.04,2,I332R +urn:mavedb:00000044-b-2#61,NA,NA,p.Ile2Asn,0.06,0.05,1,I332N +urn:mavedb:00000044-b-2#62,NA,NA,p.Ile2Asn,0.05,0.05,2,I332N +urn:mavedb:00000044-b-2#45,NA,NA,p.Ile2Asp,0,0.03,1,I332D +urn:mavedb:00000044-b-2#46,NA,NA,p.Ile2Asp,0.06,0.03,2,I332D +urn:mavedb:00000044-b-2#43,NA,NA,p.Ile2Cys,-0.1,-0.12,1,I332C +urn:mavedb:00000044-b-2#44,NA,NA,p.Ile2Cys,-0.13,-0.12,2,I332C +urn:mavedb:00000044-b-2#65,NA,NA,p.Ile2Gln,0.02,0.07,1,I332Q +urn:mavedb:00000044-b-2#66,NA,NA,p.Ile2Gln,0.12,0.07,2,I332Q +urn:mavedb:00000044-b-2#47,NA,NA,p.Ile2Glu,-0.05,0.01,1,I332E +urn:mavedb:00000044-b-2#48,NA,NA,p.Ile2Glu,0.07,0.01,2,I332E +urn:mavedb:00000044-b-2#51,NA,NA,p.Ile2Gly,0.14,0.14,1,I332G +urn:mavedb:00000044-b-2#52,NA,NA,p.Ile2Gly,0.14,0.14,2,I332G +urn:mavedb:00000044-b-2#53,NA,NA,p.Ile2His,0.05,0.05,1,I332H +urn:mavedb:00000044-b-2#54,NA,NA,p.Ile2His,0.05,0.05,2,I332H +urn:mavedb:00000044-b-2#57,NA,NA,p.Ile2Leu,0.03,-0.03,1,I332L +urn:mavedb:00000044-b-2#58,NA,NA,p.Ile2Leu,-0.08,-0.03,2,I332L +urn:mavedb:00000044-b-2#55,NA,NA,p.Ile2Lys,-0.13,-0.06,1,I332K +urn:mavedb:00000044-b-2#56,NA,NA,p.Ile2Lys,0,-0.06,2,I332K +urn:mavedb:00000044-b-2#59,NA,NA,p.Ile2Met,-0.02,-0.02,1,I332M +urn:mavedb:00000044-b-2#60,NA,NA,p.Ile2Met,-0.01,-0.02,2,I332M +urn:mavedb:00000044-b-2#49,NA,NA,p.Ile2Phe,-0.12,-0.1,1,I332F +urn:mavedb:00000044-b-2#50,NA,NA,p.Ile2Phe,-0.09,-0.1,2,I332F +urn:mavedb:00000044-b-2#63,NA,NA,p.Ile2Pro,-0.14,-0.17,1,I332P +urn:mavedb:00000044-b-2#64,NA,NA,p.Ile2Pro,-0.2,-0.17,2,I332P +urn:mavedb:00000044-b-2#69,NA,NA,p.Ile2Ser,0.01,-0.03,1,I332S +urn:mavedb:00000044-b-2#70,NA,NA,p.Ile2Ser,-0.08,-0.03,2,I332S +urn:mavedb:00000044-b-2#71,NA,NA,p.Ile2Thr,-0.07,-0.04,1,I332T +urn:mavedb:00000044-b-2#72,NA,NA,p.Ile2Thr,-0.01,-0.04,2,I332T +urn:mavedb:00000044-b-2#75,NA,NA,p.Ile2Trp,-0.46,-0.33,1,I332W +urn:mavedb:00000044-b-2#76,NA,NA,p.Ile2Trp,-0.21,-0.33,2,I332W +urn:mavedb:00000044-b-2#77,NA,NA,p.Ile2Tyr,-0.04,-0.07,1,I332Y +urn:mavedb:00000044-b-2#78,NA,NA,p.Ile2Tyr,-0.09,-0.07,2,I332Y +urn:mavedb:00000044-b-2#73,NA,NA,p.Ile2Val,0.02,0.02,1,I332V +urn:mavedb:00000044-b-2#74,NA,NA,p.Ile2Val,0.02,0.02,2,I332V +urn:mavedb:00000044-b-2#2879,NA,NA,p.Ile72*,-4.58,-4.56,1,I402 +urn:mavedb:00000044-b-2#2880,NA,NA,p.Ile72*,-4.54,-4.56,2,I402 +urn:mavedb:00000044-b-2#2841,NA,NA,p.Ile72Ala,-2.28,-2.29,1,I402A +urn:mavedb:00000044-b-2#2842,NA,NA,p.Ile72Ala,-2.31,-2.29,2,I402A +urn:mavedb:00000044-b-2#2867,NA,NA,p.Ile72Arg,-2.89,-2.76,1,I402R +urn:mavedb:00000044-b-2#2868,NA,NA,p.Ile72Arg,-2.63,-2.76,2,I402R +urn:mavedb:00000044-b-2#2861,NA,NA,p.Ile72Asn,-2.81,-2.79,1,I402N +urn:mavedb:00000044-b-2#2862,NA,NA,p.Ile72Asn,-2.78,-2.79,2,I402N +urn:mavedb:00000044-b-2#2845,NA,NA,p.Ile72Asp,-2.58,-2.64,1,I402D +urn:mavedb:00000044-b-2#2846,NA,NA,p.Ile72Asp,-2.69,-2.64,2,I402D +urn:mavedb:00000044-b-2#2843,NA,NA,p.Ile72Cys,-0.69,-0.89,1,I402C +urn:mavedb:00000044-b-2#2844,NA,NA,p.Ile72Cys,-1.1,-0.89,2,I402C +urn:mavedb:00000044-b-2#2865,NA,NA,p.Ile72Gln,-2.89,-2.82,1,I402Q +urn:mavedb:00000044-b-2#2866,NA,NA,p.Ile72Gln,-2.75,-2.82,2,I402Q +urn:mavedb:00000044-b-2#2847,NA,NA,p.Ile72Glu,-2.55,-2.71,1,I402E +urn:mavedb:00000044-b-2#2848,NA,NA,p.Ile72Glu,-2.88,-2.71,2,I402E +urn:mavedb:00000044-b-2#2851,NA,NA,p.Ile72Gly,-2.75,-2.75,1,I402G +urn:mavedb:00000044-b-2#2852,NA,NA,p.Ile72Gly,-2.75,-2.75,2,I402G +urn:mavedb:00000044-b-2#2853,NA,NA,p.Ile72His,-2.88,-2.84,1,I402H +urn:mavedb:00000044-b-2#2854,NA,NA,p.Ile72His,-2.79,-2.84,2,I402H +urn:mavedb:00000044-b-2#2857,NA,NA,p.Ile72Leu,-0.39,-0.41,1,I402L +urn:mavedb:00000044-b-2#2858,NA,NA,p.Ile72Leu,-0.43,-0.41,2,I402L +urn:mavedb:00000044-b-2#2855,NA,NA,p.Ile72Lys,-2.84,-2.78,1,I402K +urn:mavedb:00000044-b-2#2856,NA,NA,p.Ile72Lys,-2.72,-2.78,2,I402K +urn:mavedb:00000044-b-2#2859,NA,NA,p.Ile72Met,-2.4,-2.29,1,I402M +urn:mavedb:00000044-b-2#2860,NA,NA,p.Ile72Met,-2.17,-2.29,2,I402M +urn:mavedb:00000044-b-2#2849,NA,NA,p.Ile72Phe,-2.86,-2.8,1,I402F +urn:mavedb:00000044-b-2#2850,NA,NA,p.Ile72Phe,-2.74,-2.8,2,I402F +urn:mavedb:00000044-b-2#2863,NA,NA,p.Ile72Pro,-2.92,-2.83,1,I402P +urn:mavedb:00000044-b-2#2864,NA,NA,p.Ile72Pro,-2.75,-2.83,2,I402P +urn:mavedb:00000044-b-2#2869,NA,NA,p.Ile72Ser,-2.62,-2.68,1,I402S +urn:mavedb:00000044-b-2#2870,NA,NA,p.Ile72Ser,-2.74,-2.68,2,I402S +urn:mavedb:00000044-b-2#2871,NA,NA,p.Ile72Thr,-2.08,-1.99,1,I402T +urn:mavedb:00000044-b-2#2872,NA,NA,p.Ile72Thr,-1.9,-1.99,2,I402T +urn:mavedb:00000044-b-2#2875,NA,NA,p.Ile72Trp,-2.87,-2.65,1,I402W +urn:mavedb:00000044-b-2#2876,NA,NA,p.Ile72Trp,-2.42,-2.65,2,I402W +urn:mavedb:00000044-b-2#2877,NA,NA,p.Ile72Tyr,-2.94,-2.81,1,I402Y +urn:mavedb:00000044-b-2#2878,NA,NA,p.Ile72Tyr,-2.68,-2.81,2,I402Y +urn:mavedb:00000044-b-2#2873,NA,NA,p.Ile72Val,0.02,0.1,1,I402V +urn:mavedb:00000044-b-2#2874,NA,NA,p.Ile72Val,0.18,0.1,2,I402V +urn:mavedb:00000044-b-2#3199,NA,NA,p.Ile80*,-4.6,-4.52,1,I410 +urn:mavedb:00000044-b-2#3200,NA,NA,p.Ile80*,-4.44,-4.52,2,I410 +urn:mavedb:00000044-b-2#3161,NA,NA,p.Ile80Ala,-2.83,-2.82,1,I410A +urn:mavedb:00000044-b-2#3162,NA,NA,p.Ile80Ala,-2.82,-2.82,2,I410A +urn:mavedb:00000044-b-2#3187,NA,NA,p.Ile80Arg,-2.89,-2.84,1,I410R +urn:mavedb:00000044-b-2#3188,NA,NA,p.Ile80Arg,-2.79,-2.84,2,I410R +urn:mavedb:00000044-b-2#3181,NA,NA,p.Ile80Asn,-2.86,-2.66,1,I410N +urn:mavedb:00000044-b-2#3182,NA,NA,p.Ile80Asn,-2.46,-2.66,2,I410N +urn:mavedb:00000044-b-2#3165,NA,NA,p.Ile80Asp,-3.11,-2.94,1,I410D +urn:mavedb:00000044-b-2#3166,NA,NA,p.Ile80Asp,-2.78,-2.94,2,I410D +urn:mavedb:00000044-b-2#3163,NA,NA,p.Ile80Cys,-2.87,-2.69,1,I410C +urn:mavedb:00000044-b-2#3164,NA,NA,p.Ile80Cys,-2.5,-2.69,2,I410C +urn:mavedb:00000044-b-2#3185,NA,NA,p.Ile80Gln,-2.99,-2.83,1,I410Q +urn:mavedb:00000044-b-2#3186,NA,NA,p.Ile80Gln,-2.66,-2.83,2,I410Q +urn:mavedb:00000044-b-2#3167,NA,NA,p.Ile80Glu,-2.7,-2.7,1,I410E +urn:mavedb:00000044-b-2#3168,NA,NA,p.Ile80Glu,-2.7,-2.7,2,I410E +urn:mavedb:00000044-b-2#3171,NA,NA,p.Ile80Gly,-2.86,-2.81,1,I410G +urn:mavedb:00000044-b-2#3172,NA,NA,p.Ile80Gly,-2.75,-2.81,2,I410G +urn:mavedb:00000044-b-2#3173,NA,NA,p.Ile80His,-2.89,-2.89,1,I410H +urn:mavedb:00000044-b-2#3174,NA,NA,p.Ile80His,-2.88,-2.89,2,I410H +urn:mavedb:00000044-b-2#3177,NA,NA,p.Ile80Leu,-1.36,-1.45,1,I410L +urn:mavedb:00000044-b-2#3178,NA,NA,p.Ile80Leu,-1.53,-1.45,2,I410L +urn:mavedb:00000044-b-2#3175,NA,NA,p.Ile80Lys,-2.86,-2.76,1,I410K +urn:mavedb:00000044-b-2#3176,NA,NA,p.Ile80Lys,-2.66,-2.76,2,I410K +urn:mavedb:00000044-b-2#3179,NA,NA,p.Ile80Met,-2.25,-2.28,1,I410M +urn:mavedb:00000044-b-2#3180,NA,NA,p.Ile80Met,-2.3,-2.28,2,I410M +urn:mavedb:00000044-b-2#3169,NA,NA,p.Ile80Phe,-2.86,-2.69,1,I410F +urn:mavedb:00000044-b-2#3170,NA,NA,p.Ile80Phe,-2.51,-2.69,2,I410F +urn:mavedb:00000044-b-2#3183,NA,NA,p.Ile80Pro,-2.78,-2.54,1,I410P +urn:mavedb:00000044-b-2#3184,NA,NA,p.Ile80Pro,-2.3,-2.54,2,I410P +urn:mavedb:00000044-b-2#3189,NA,NA,p.Ile80Ser,-2.64,-2.65,1,I410S +urn:mavedb:00000044-b-2#3190,NA,NA,p.Ile80Ser,-2.66,-2.65,2,I410S +urn:mavedb:00000044-b-2#3191,NA,NA,p.Ile80Thr,-2.86,-2.76,1,I410T +urn:mavedb:00000044-b-2#3192,NA,NA,p.Ile80Thr,-2.67,-2.76,2,I410T +urn:mavedb:00000044-b-2#3195,NA,NA,p.Ile80Trp,-2.88,-2.79,1,I410W +urn:mavedb:00000044-b-2#3196,NA,NA,p.Ile80Trp,-2.71,-2.79,2,I410W +urn:mavedb:00000044-b-2#3197,NA,NA,p.Ile80Tyr,-2.6,-2.68,1,I410Y +urn:mavedb:00000044-b-2#3198,NA,NA,p.Ile80Tyr,-2.75,-2.68,2,I410Y +urn:mavedb:00000044-b-2#3193,NA,NA,p.Ile80Val,-0.52,-0.6,1,I410V +urn:mavedb:00000044-b-2#3194,NA,NA,p.Ile80Val,-0.67,-0.6,2,I410V +urn:mavedb:00000044-b-2#3519,NA,NA,p.Ile88*,-4.65,-4.61,1,I418 +urn:mavedb:00000044-b-2#3520,NA,NA,p.Ile88*,-4.58,-4.61,2,I418 +urn:mavedb:00000044-b-2#3481,NA,NA,p.Ile88Ala,-2.86,-2.77,1,I418A +urn:mavedb:00000044-b-2#3482,NA,NA,p.Ile88Ala,-2.68,-2.77,2,I418A +urn:mavedb:00000044-b-2#3507,NA,NA,p.Ile88Arg,-2.83,-2.74,1,I418R +urn:mavedb:00000044-b-2#3508,NA,NA,p.Ile88Arg,-2.64,-2.74,2,I418R +urn:mavedb:00000044-b-2#3501,NA,NA,p.Ile88Asn,-2.86,-2.72,1,I418N +urn:mavedb:00000044-b-2#3502,NA,NA,p.Ile88Asn,-2.57,-2.72,2,I418N +urn:mavedb:00000044-b-2#3485,NA,NA,p.Ile88Asp,-2.76,-2.65,1,I418D +urn:mavedb:00000044-b-2#3486,NA,NA,p.Ile88Asp,-2.53,-2.65,2,I418D +urn:mavedb:00000044-b-2#3483,NA,NA,p.Ile88Cys,-2.48,-2.5,1,I418C +urn:mavedb:00000044-b-2#3484,NA,NA,p.Ile88Cys,-2.51,-2.5,2,I418C +urn:mavedb:00000044-b-2#3505,NA,NA,p.Ile88Gln,-2.78,-2.76,1,I418Q +urn:mavedb:00000044-b-2#3506,NA,NA,p.Ile88Gln,-2.73,-2.76,2,I418Q +urn:mavedb:00000044-b-2#3487,NA,NA,p.Ile88Glu,-2.66,-2.7,1,I418E +urn:mavedb:00000044-b-2#3488,NA,NA,p.Ile88Glu,-2.74,-2.7,2,I418E +urn:mavedb:00000044-b-2#3491,NA,NA,p.Ile88Gly,-2.69,-2.64,1,I418G +urn:mavedb:00000044-b-2#3492,NA,NA,p.Ile88Gly,-2.58,-2.64,2,I418G +urn:mavedb:00000044-b-2#3493,NA,NA,p.Ile88His,-2.66,-2.7,1,I418H +urn:mavedb:00000044-b-2#3494,NA,NA,p.Ile88His,-2.73,-2.7,2,I418H +urn:mavedb:00000044-b-2#3497,NA,NA,p.Ile88Leu,-1.99,-2,1,I418L +urn:mavedb:00000044-b-2#3498,NA,NA,p.Ile88Leu,-2.01,-2,2,I418L +urn:mavedb:00000044-b-2#3495,NA,NA,p.Ile88Lys,-2.8,-2.68,1,I418K +urn:mavedb:00000044-b-2#3496,NA,NA,p.Ile88Lys,-2.56,-2.68,2,I418K +urn:mavedb:00000044-b-2#3499,NA,NA,p.Ile88Met,-2.41,-2.23,1,I418M +urn:mavedb:00000044-b-2#3500,NA,NA,p.Ile88Met,-2.06,-2.23,2,I418M +urn:mavedb:00000044-b-2#3489,NA,NA,p.Ile88Phe,-2.41,-2.42,1,I418F +urn:mavedb:00000044-b-2#3490,NA,NA,p.Ile88Phe,-2.44,-2.42,2,I418F +urn:mavedb:00000044-b-2#3503,NA,NA,p.Ile88Pro,-2.89,-2.8,1,I418P +urn:mavedb:00000044-b-2#3504,NA,NA,p.Ile88Pro,-2.71,-2.8,2,I418P +urn:mavedb:00000044-b-2#3509,NA,NA,p.Ile88Ser,-2.7,-2.7,1,I418S +urn:mavedb:00000044-b-2#3510,NA,NA,p.Ile88Ser,-2.71,-2.7,2,I418S +urn:mavedb:00000044-b-2#3511,NA,NA,p.Ile88Thr,-2.58,-2.42,1,I418T +urn:mavedb:00000044-b-2#3512,NA,NA,p.Ile88Thr,-2.26,-2.42,2,I418T +urn:mavedb:00000044-b-2#3515,NA,NA,p.Ile88Trp,-2.89,-2.76,1,I418W +urn:mavedb:00000044-b-2#3516,NA,NA,p.Ile88Trp,-2.63,-2.76,2,I418W +urn:mavedb:00000044-b-2#3517,NA,NA,p.Ile88Tyr,-2.87,-2.77,1,I418Y +urn:mavedb:00000044-b-2#3518,NA,NA,p.Ile88Tyr,-2.67,-2.77,2,I418Y +urn:mavedb:00000044-b-2#3513,NA,NA,p.Ile88Val,-0.5,-0.59,1,I418V +urn:mavedb:00000044-b-2#3514,NA,NA,p.Ile88Val,-0.67,-0.59,2,I418V +urn:mavedb:00000044-b-2#4439,NA,NA,p.Leu111*,-3.78,-3.55,1,L441 +urn:mavedb:00000044-b-2#4440,NA,NA,p.Leu111*,-3.32,-3.55,2,L441 +urn:mavedb:00000044-b-2#4401,NA,NA,p.Leu111Ala,-0.07,-0.19,1,L441A +urn:mavedb:00000044-b-2#4402,NA,NA,p.Leu111Ala,-0.31,-0.19,2,L441A +urn:mavedb:00000044-b-2#4427,NA,NA,p.Leu111Arg,-1.41,-0.89,1,L441R +urn:mavedb:00000044-b-2#4428,NA,NA,p.Leu111Arg,-0.37,-0.89,2,L441R +urn:mavedb:00000044-b-2#4421,NA,NA,p.Leu111Asn,0.28,0.01,1,L441N +urn:mavedb:00000044-b-2#4422,NA,NA,p.Leu111Asn,-0.26,0.01,2,L441N +urn:mavedb:00000044-b-2#4405,NA,NA,p.Leu111Asp,-0.24,-0.26,1,L441D +urn:mavedb:00000044-b-2#4406,NA,NA,p.Leu111Asp,-0.28,-0.26,2,L441D +urn:mavedb:00000044-b-2#4403,NA,NA,p.Leu111Cys,-2.92,-1.44,1,L441C +urn:mavedb:00000044-b-2#4404,NA,NA,p.Leu111Cys,0.03,-1.44,2,L441C +urn:mavedb:00000044-b-2#4425,NA,NA,p.Leu111Gln,0.44,0.21,1,L441Q +urn:mavedb:00000044-b-2#4426,NA,NA,p.Leu111Gln,-0.03,0.21,2,L441Q +urn:mavedb:00000044-b-2#4407,NA,NA,p.Leu111Glu,-0.08,-0.06,1,L441E +urn:mavedb:00000044-b-2#4408,NA,NA,p.Leu111Glu,-0.04,-0.06,2,L441E +urn:mavedb:00000044-b-2#4411,NA,NA,p.Leu111Gly,-2.07,-1.64,1,L441G +urn:mavedb:00000044-b-2#4412,NA,NA,p.Leu111Gly,-1.21,-1.64,2,L441G +urn:mavedb:00000044-b-2#4413,NA,NA,p.Leu111His,-0.66,-0.48,1,L441H +urn:mavedb:00000044-b-2#4414,NA,NA,p.Leu111His,-0.3,-0.48,2,L441H +urn:mavedb:00000044-b-2#4415,NA,NA,p.Leu111Ile,0.16,0.25,1,L441I +urn:mavedb:00000044-b-2#4416,NA,NA,p.Leu111Ile,0.35,0.25,2,L441I +urn:mavedb:00000044-b-2#4417,NA,NA,p.Leu111Lys,-0.23,-0.18,1,L441K +urn:mavedb:00000044-b-2#4418,NA,NA,p.Leu111Lys,-0.13,-0.18,2,L441K +urn:mavedb:00000044-b-2#4419,NA,NA,p.Leu111Met,0.12,0.06,1,L441M +urn:mavedb:00000044-b-2#4420,NA,NA,p.Leu111Met,0,0.06,2,L441M +urn:mavedb:00000044-b-2#4409,NA,NA,p.Leu111Phe,-0.44,-0.35,1,L441F +urn:mavedb:00000044-b-2#4410,NA,NA,p.Leu111Phe,-0.27,-0.35,2,L441F +urn:mavedb:00000044-b-2#4423,NA,NA,p.Leu111Pro,-1.34,-1.12,1,L441P +urn:mavedb:00000044-b-2#4424,NA,NA,p.Leu111Pro,-0.91,-1.12,2,L441P +urn:mavedb:00000044-b-2#4429,NA,NA,p.Leu111Ser,-0.22,-0.33,1,L441S +urn:mavedb:00000044-b-2#4430,NA,NA,p.Leu111Ser,-0.43,-0.33,2,L441S +urn:mavedb:00000044-b-2#4431,NA,NA,p.Leu111Thr,-0.21,-0.4,1,L441T +urn:mavedb:00000044-b-2#4432,NA,NA,p.Leu111Thr,-0.58,-0.4,2,L441T +urn:mavedb:00000044-b-2#4435,NA,NA,p.Leu111Trp,-0.42,-0.37,1,L441W +urn:mavedb:00000044-b-2#4436,NA,NA,p.Leu111Trp,-0.32,-0.37,2,L441W +urn:mavedb:00000044-b-2#4437,NA,NA,p.Leu111Tyr,-0.37,-0.5,1,L441Y +urn:mavedb:00000044-b-2#4438,NA,NA,p.Leu111Tyr,-0.63,-0.5,2,L441Y +urn:mavedb:00000044-b-2#4433,NA,NA,p.Leu111Val,0.3,0.15,1,L441V +urn:mavedb:00000044-b-2#4434,NA,NA,p.Leu111Val,0,0.15,2,L441V +urn:mavedb:00000044-b-2#4879,NA,NA,p.Leu122*,-4.59,-4.55,1,L452 +urn:mavedb:00000044-b-2#4880,NA,NA,p.Leu122*,-4.51,-4.55,2,L452 +urn:mavedb:00000044-b-2#4841,NA,NA,p.Leu122Ala,0.05,0.03,1,L452A +urn:mavedb:00000044-b-2#4842,NA,NA,p.Leu122Ala,0.01,0.03,2,L452A +urn:mavedb:00000044-b-2#4867,NA,NA,p.Leu122Arg,0.2,0.32,1,L452R +urn:mavedb:00000044-b-2#4868,NA,NA,p.Leu122Arg,0.44,0.32,2,L452R +urn:mavedb:00000044-b-2#4861,NA,NA,p.Leu122Asn,-0.16,-0.13,1,L452N +urn:mavedb:00000044-b-2#4862,NA,NA,p.Leu122Asn,-0.1,-0.13,2,L452N +urn:mavedb:00000044-b-2#4845,NA,NA,p.Leu122Asp,-0.44,-0.41,1,L452D +urn:mavedb:00000044-b-2#4846,NA,NA,p.Leu122Asp,-0.37,-0.41,2,L452D +urn:mavedb:00000044-b-2#4843,NA,NA,p.Leu122Cys,-0.04,-0.11,1,L452C +urn:mavedb:00000044-b-2#4844,NA,NA,p.Leu122Cys,-0.18,-0.11,2,L452C +urn:mavedb:00000044-b-2#4865,NA,NA,p.Leu122Gln,0.29,0.27,1,L452Q +urn:mavedb:00000044-b-2#4866,NA,NA,p.Leu122Gln,0.25,0.27,2,L452Q +urn:mavedb:00000044-b-2#4847,NA,NA,p.Leu122Glu,0.03,0.08,1,L452E +urn:mavedb:00000044-b-2#4848,NA,NA,p.Leu122Glu,0.13,0.08,2,L452E +urn:mavedb:00000044-b-2#4851,NA,NA,p.Leu122Gly,0.02,0.02,1,L452G +urn:mavedb:00000044-b-2#4852,NA,NA,p.Leu122Gly,0.01,0.02,2,L452G +urn:mavedb:00000044-b-2#4853,NA,NA,p.Leu122His,0.21,0.17,1,L452H +urn:mavedb:00000044-b-2#4854,NA,NA,p.Leu122His,0.14,0.17,2,L452H +urn:mavedb:00000044-b-2#4855,NA,NA,p.Leu122Ile,-0.47,-0.42,1,L452I +urn:mavedb:00000044-b-2#4856,NA,NA,p.Leu122Ile,-0.36,-0.42,2,L452I +urn:mavedb:00000044-b-2#4857,NA,NA,p.Leu122Lys,0.92,0.58,1,L452K +urn:mavedb:00000044-b-2#4858,NA,NA,p.Leu122Lys,0.24,0.58,2,L452K +urn:mavedb:00000044-b-2#4859,NA,NA,p.Leu122Met,0.11,0.16,1,L452M +urn:mavedb:00000044-b-2#4860,NA,NA,p.Leu122Met,0.2,0.16,2,L452M +urn:mavedb:00000044-b-2#4849,NA,NA,p.Leu122Phe,0.09,0.05,1,L452F +urn:mavedb:00000044-b-2#4850,NA,NA,p.Leu122Phe,0.01,0.05,2,L452F +urn:mavedb:00000044-b-2#4863,NA,NA,p.Leu122Pro,-2.43,-2.45,1,L452P +urn:mavedb:00000044-b-2#4864,NA,NA,p.Leu122Pro,-2.47,-2.45,2,L452P +urn:mavedb:00000044-b-2#4869,NA,NA,p.Leu122Ser,0.53,0.4,1,L452S +urn:mavedb:00000044-b-2#4870,NA,NA,p.Leu122Ser,0.26,0.4,2,L452S +urn:mavedb:00000044-b-2#4871,NA,NA,p.Leu122Thr,0.1,0.09,1,L452T +urn:mavedb:00000044-b-2#4872,NA,NA,p.Leu122Thr,0.08,0.09,2,L452T +urn:mavedb:00000044-b-2#4875,NA,NA,p.Leu122Trp,-0.02,0.03,1,L452W +urn:mavedb:00000044-b-2#4876,NA,NA,p.Leu122Trp,0.07,0.03,2,L452W +urn:mavedb:00000044-b-2#4877,NA,NA,p.Leu122Tyr,0.09,0.14,1,L452Y +urn:mavedb:00000044-b-2#4878,NA,NA,p.Leu122Tyr,0.2,0.14,2,L452Y +urn:mavedb:00000044-b-2#4873,NA,NA,p.Leu122Val,-0.1,-0.1,1,L452V +urn:mavedb:00000044-b-2#4874,NA,NA,p.Leu122Val,-0.09,-0.1,2,L452V +urn:mavedb:00000044-b-2#4999,NA,NA,p.Leu125*,-4.29,-4.43,1,L455 +urn:mavedb:00000044-b-2#5000,NA,NA,p.Leu125*,-4.57,-4.43,2,L455 +urn:mavedb:00000044-b-2#4961,NA,NA,p.Leu125Ala,0.45,0.58,1,L455A +urn:mavedb:00000044-b-2#4962,NA,NA,p.Leu125Ala,0.7,0.58,2,L455A +urn:mavedb:00000044-b-2#4987,NA,NA,p.Leu125Arg,0.6,0.74,1,L455R +urn:mavedb:00000044-b-2#4988,NA,NA,p.Leu125Arg,0.88,0.74,2,L455R +urn:mavedb:00000044-b-2#4981,NA,NA,p.Leu125Asn,0.79,0.79,1,L455N +urn:mavedb:00000044-b-2#4982,NA,NA,p.Leu125Asn,NA,0.79,2,L455N +urn:mavedb:00000044-b-2#4965,NA,NA,p.Leu125Asp,0.15,0.19,1,L455D +urn:mavedb:00000044-b-2#4966,NA,NA,p.Leu125Asp,0.23,0.19,2,L455D +urn:mavedb:00000044-b-2#4963,NA,NA,p.Leu125Cys,0.29,0.23,1,L455C +urn:mavedb:00000044-b-2#4964,NA,NA,p.Leu125Cys,0.17,0.23,2,L455C +urn:mavedb:00000044-b-2#4985,NA,NA,p.Leu125Gln,NA,NA,1,L455Q +urn:mavedb:00000044-b-2#4986,NA,NA,p.Leu125Gln,NA,NA,2,L455Q +urn:mavedb:00000044-b-2#4967,NA,NA,p.Leu125Glu,0.08,0.26,1,L455E +urn:mavedb:00000044-b-2#4968,NA,NA,p.Leu125Glu,0.45,0.26,2,L455E +urn:mavedb:00000044-b-2#4971,NA,NA,p.Leu125Gly,0.24,0.14,1,L455G +urn:mavedb:00000044-b-2#4972,NA,NA,p.Leu125Gly,0.03,0.14,2,L455G +urn:mavedb:00000044-b-2#4973,NA,NA,p.Leu125His,0.68,0.36,1,L455H +urn:mavedb:00000044-b-2#4974,NA,NA,p.Leu125His,0.05,0.36,2,L455H +urn:mavedb:00000044-b-2#4975,NA,NA,p.Leu125Ile,0.03,0.07,1,L455I +urn:mavedb:00000044-b-2#4976,NA,NA,p.Leu125Ile,0.11,0.07,2,L455I +urn:mavedb:00000044-b-2#4977,NA,NA,p.Leu125Lys,NA,0.75,1,L455K +urn:mavedb:00000044-b-2#4978,NA,NA,p.Leu125Lys,0.75,0.75,2,L455K +urn:mavedb:00000044-b-2#4979,NA,NA,p.Leu125Met,0.07,0.31,1,L455M +urn:mavedb:00000044-b-2#4980,NA,NA,p.Leu125Met,0.55,0.31,2,L455M +urn:mavedb:00000044-b-2#4969,NA,NA,p.Leu125Phe,-0.05,-0.05,1,L455F +urn:mavedb:00000044-b-2#4970,NA,NA,p.Leu125Phe,-0.05,-0.05,2,L455F +urn:mavedb:00000044-b-2#4983,NA,NA,p.Leu125Pro,0.26,0.13,1,L455P +urn:mavedb:00000044-b-2#4984,NA,NA,p.Leu125Pro,0.01,0.13,2,L455P +urn:mavedb:00000044-b-2#4989,NA,NA,p.Leu125Ser,0.12,0.45,1,L455S +urn:mavedb:00000044-b-2#4990,NA,NA,p.Leu125Ser,0.79,0.45,2,L455S +urn:mavedb:00000044-b-2#4991,NA,NA,p.Leu125Thr,0.15,0.15,1,L455T +urn:mavedb:00000044-b-2#4992,NA,NA,p.Leu125Thr,NA,0.15,2,L455T +urn:mavedb:00000044-b-2#4995,NA,NA,p.Leu125Trp,-0.07,-0.03,1,L455W +urn:mavedb:00000044-b-2#4996,NA,NA,p.Leu125Trp,0.01,-0.03,2,L455W +urn:mavedb:00000044-b-2#4997,NA,NA,p.Leu125Tyr,-0.16,-0.1,1,L455Y +urn:mavedb:00000044-b-2#4998,NA,NA,p.Leu125Tyr,-0.03,-0.1,2,L455Y +urn:mavedb:00000044-b-2#4993,NA,NA,p.Leu125Val,0.38,0.21,1,L455V +urn:mavedb:00000044-b-2#4994,NA,NA,p.Leu125Val,0.05,0.21,2,L455V +urn:mavedb:00000044-b-2#5239,NA,NA,p.Leu131*,-4.59,-4.58,1,L461 +urn:mavedb:00000044-b-2#5240,NA,NA,p.Leu131*,-4.56,-4.58,2,L461 +urn:mavedb:00000044-b-2#5201,NA,NA,p.Leu131Ala,-2.16,-2.29,1,L461A +urn:mavedb:00000044-b-2#5202,NA,NA,p.Leu131Ala,-2.42,-2.29,2,L461A +urn:mavedb:00000044-b-2#5227,NA,NA,p.Leu131Arg,-2.68,-2.61,1,L461R +urn:mavedb:00000044-b-2#5228,NA,NA,p.Leu131Arg,-2.54,-2.61,2,L461R +urn:mavedb:00000044-b-2#5221,NA,NA,p.Leu131Asn,-2.44,-2.27,1,L461N +urn:mavedb:00000044-b-2#5222,NA,NA,p.Leu131Asn,-2.11,-2.27,2,L461N +urn:mavedb:00000044-b-2#5205,NA,NA,p.Leu131Asp,-2.48,-2.36,1,L461D +urn:mavedb:00000044-b-2#5206,NA,NA,p.Leu131Asp,-2.25,-2.36,2,L461D +urn:mavedb:00000044-b-2#5203,NA,NA,p.Leu131Cys,-1.65,-1.78,1,L461C +urn:mavedb:00000044-b-2#5204,NA,NA,p.Leu131Cys,-1.91,-1.78,2,L461C +urn:mavedb:00000044-b-2#5225,NA,NA,p.Leu131Gln,-2.71,-2.73,1,L461Q +urn:mavedb:00000044-b-2#5226,NA,NA,p.Leu131Gln,-2.75,-2.73,2,L461Q +urn:mavedb:00000044-b-2#5207,NA,NA,p.Leu131Glu,-2.37,-2.34,1,L461E +urn:mavedb:00000044-b-2#5208,NA,NA,p.Leu131Glu,-2.3,-2.34,2,L461E +urn:mavedb:00000044-b-2#5211,NA,NA,p.Leu131Gly,-2.44,-2.37,1,L461G +urn:mavedb:00000044-b-2#5212,NA,NA,p.Leu131Gly,-2.29,-2.37,2,L461G +urn:mavedb:00000044-b-2#5213,NA,NA,p.Leu131His,-2.4,-2.47,1,L461H +urn:mavedb:00000044-b-2#5214,NA,NA,p.Leu131His,-2.53,-2.47,2,L461H +urn:mavedb:00000044-b-2#5215,NA,NA,p.Leu131Ile,0,0,1,L461I +urn:mavedb:00000044-b-2#5216,NA,NA,p.Leu131Ile,0.01,0,2,L461I +urn:mavedb:00000044-b-2#5217,NA,NA,p.Leu131Lys,-2.55,-2.4,1,L461K +urn:mavedb:00000044-b-2#5218,NA,NA,p.Leu131Lys,-2.25,-2.4,2,L461K +urn:mavedb:00000044-b-2#5219,NA,NA,p.Leu131Met,-1.17,-0.82,1,L461M +urn:mavedb:00000044-b-2#5220,NA,NA,p.Leu131Met,-0.47,-0.82,2,L461M +urn:mavedb:00000044-b-2#5209,NA,NA,p.Leu131Phe,-2.24,-2.19,1,L461F +urn:mavedb:00000044-b-2#5210,NA,NA,p.Leu131Phe,-2.15,-2.19,2,L461F +urn:mavedb:00000044-b-2#5223,NA,NA,p.Leu131Pro,-2.58,-2.55,1,L461P +urn:mavedb:00000044-b-2#5224,NA,NA,p.Leu131Pro,-2.52,-2.55,2,L461P +urn:mavedb:00000044-b-2#5229,NA,NA,p.Leu131Ser,-2.55,-2.41,1,L461S +urn:mavedb:00000044-b-2#5230,NA,NA,p.Leu131Ser,-2.27,-2.41,2,L461S +urn:mavedb:00000044-b-2#5231,NA,NA,p.Leu131Thr,-2.04,-2.04,1,L461T +urn:mavedb:00000044-b-2#5232,NA,NA,p.Leu131Thr,-2.04,-2.04,2,L461T +urn:mavedb:00000044-b-2#5235,NA,NA,p.Leu131Trp,-2.61,-2.52,1,L461W +urn:mavedb:00000044-b-2#5236,NA,NA,p.Leu131Trp,-2.43,-2.52,2,L461W +urn:mavedb:00000044-b-2#5237,NA,NA,p.Leu131Tyr,-2.67,-2.47,1,L461Y +urn:mavedb:00000044-b-2#5238,NA,NA,p.Leu131Tyr,-2.28,-2.47,2,L461Y +urn:mavedb:00000044-b-2#5233,NA,NA,p.Leu131Val,-0.22,-0.28,1,L461V +urn:mavedb:00000044-b-2#5234,NA,NA,p.Leu131Val,-0.34,-0.28,2,L461V +urn:mavedb:00000044-b-2#6479,NA,NA,p.Leu162*,-4.61,-4.57,1,L492 +urn:mavedb:00000044-b-2#6480,NA,NA,p.Leu162*,-4.54,-4.57,2,L492 +urn:mavedb:00000044-b-2#6441,NA,NA,p.Leu162Ala,-2.03,-2.22,1,L492A +urn:mavedb:00000044-b-2#6442,NA,NA,p.Leu162Ala,-2.4,-2.22,2,L492A +urn:mavedb:00000044-b-2#6467,NA,NA,p.Leu162Arg,-2.38,-2.28,1,L492R +urn:mavedb:00000044-b-2#6468,NA,NA,p.Leu162Arg,-2.18,-2.28,2,L492R +urn:mavedb:00000044-b-2#6461,NA,NA,p.Leu162Asn,-2.23,-1.53,1,L492N +urn:mavedb:00000044-b-2#6462,NA,NA,p.Leu162Asn,-0.82,-1.53,2,L492N +urn:mavedb:00000044-b-2#6445,NA,NA,p.Leu162Asp,-2.4,-2.45,1,L492D +urn:mavedb:00000044-b-2#6446,NA,NA,p.Leu162Asp,-2.49,-2.45,2,L492D +urn:mavedb:00000044-b-2#6443,NA,NA,p.Leu162Cys,-2.17,-2,1,L492C +urn:mavedb:00000044-b-2#6444,NA,NA,p.Leu162Cys,-1.84,-2,2,L492C +urn:mavedb:00000044-b-2#6465,NA,NA,p.Leu162Gln,-2.24,-2.36,1,L492Q +urn:mavedb:00000044-b-2#6466,NA,NA,p.Leu162Gln,-2.47,-2.36,2,L492Q +urn:mavedb:00000044-b-2#6447,NA,NA,p.Leu162Glu,-2.62,-2.47,1,L492E +urn:mavedb:00000044-b-2#6448,NA,NA,p.Leu162Glu,-2.32,-2.47,2,L492E +urn:mavedb:00000044-b-2#6451,NA,NA,p.Leu162Gly,-2.33,-2.45,1,L492G +urn:mavedb:00000044-b-2#6452,NA,NA,p.Leu162Gly,-2.56,-2.45,2,L492G +urn:mavedb:00000044-b-2#6453,NA,NA,p.Leu162His,-2.33,-2.14,1,L492H +urn:mavedb:00000044-b-2#6454,NA,NA,p.Leu162His,-1.94,-2.14,2,L492H +urn:mavedb:00000044-b-2#6455,NA,NA,p.Leu162Ile,-0.31,-0.36,1,L492I +urn:mavedb:00000044-b-2#6456,NA,NA,p.Leu162Ile,-0.4,-0.36,2,L492I +urn:mavedb:00000044-b-2#6457,NA,NA,p.Leu162Lys,-2.47,-2.39,1,L492K +urn:mavedb:00000044-b-2#6458,NA,NA,p.Leu162Lys,-2.32,-2.39,2,L492K +urn:mavedb:00000044-b-2#6459,NA,NA,p.Leu162Met,-0.89,-1.07,1,L492M +urn:mavedb:00000044-b-2#6460,NA,NA,p.Leu162Met,-1.25,-1.07,2,L492M +urn:mavedb:00000044-b-2#6449,NA,NA,p.Leu162Phe,-0.65,-0.95,1,L492F +urn:mavedb:00000044-b-2#6450,NA,NA,p.Leu162Phe,-1.26,-0.95,2,L492F +urn:mavedb:00000044-b-2#6463,NA,NA,p.Leu162Pro,-2.5,-2.47,1,L492P +urn:mavedb:00000044-b-2#6464,NA,NA,p.Leu162Pro,-2.45,-2.47,2,L492P +urn:mavedb:00000044-b-2#6469,NA,NA,p.Leu162Ser,-2.37,-2.41,1,L492S +urn:mavedb:00000044-b-2#6470,NA,NA,p.Leu162Ser,-2.44,-2.41,2,L492S +urn:mavedb:00000044-b-2#6471,NA,NA,p.Leu162Thr,-1.83,-1.86,1,L492T +urn:mavedb:00000044-b-2#6472,NA,NA,p.Leu162Thr,-1.89,-1.86,2,L492T +urn:mavedb:00000044-b-2#6475,NA,NA,p.Leu162Trp,-2.66,-2.54,1,L492W +urn:mavedb:00000044-b-2#6476,NA,NA,p.Leu162Trp,-2.43,-2.54,2,L492W +urn:mavedb:00000044-b-2#6477,NA,NA,p.Leu162Tyr,-2.34,-2.28,1,L492Y +urn:mavedb:00000044-b-2#6478,NA,NA,p.Leu162Tyr,-2.22,-2.28,2,L492Y +urn:mavedb:00000044-b-2#6473,NA,NA,p.Leu162Val,-0.86,-0.86,1,L492V +urn:mavedb:00000044-b-2#6474,NA,NA,p.Leu162Val,-0.87,-0.86,2,L492V +urn:mavedb:00000044-b-2#7319,NA,NA,p.Leu183*,-4.29,-3.88,1,L513 +urn:mavedb:00000044-b-2#7320,NA,NA,p.Leu183*,-3.47,-3.88,2,L513 +urn:mavedb:00000044-b-2#7281,NA,NA,p.Leu183Ala,-2.97,-2.92,1,L513A +urn:mavedb:00000044-b-2#7282,NA,NA,p.Leu183Ala,-2.86,-2.92,2,L513A +urn:mavedb:00000044-b-2#7307,NA,NA,p.Leu183Arg,-3.52,-3.47,1,L513R +urn:mavedb:00000044-b-2#7308,NA,NA,p.Leu183Arg,-3.42,-3.47,2,L513R +urn:mavedb:00000044-b-2#7301,NA,NA,p.Leu183Asn,-3.1,-3.22,1,L513N +urn:mavedb:00000044-b-2#7302,NA,NA,p.Leu183Asn,-3.33,-3.22,2,L513N +urn:mavedb:00000044-b-2#7285,NA,NA,p.Leu183Asp,-3.86,-3.74,1,L513D +urn:mavedb:00000044-b-2#7286,NA,NA,p.Leu183Asp,-3.61,-3.74,2,L513D +urn:mavedb:00000044-b-2#7283,NA,NA,p.Leu183Cys,-2.76,-2.78,1,L513C +urn:mavedb:00000044-b-2#7284,NA,NA,p.Leu183Cys,-2.79,-2.78,2,L513C +urn:mavedb:00000044-b-2#7305,NA,NA,p.Leu183Gln,-3.48,-3.34,1,L513Q +urn:mavedb:00000044-b-2#7306,NA,NA,p.Leu183Gln,-3.21,-3.34,2,L513Q +urn:mavedb:00000044-b-2#7287,NA,NA,p.Leu183Glu,-3.62,-3.53,1,L513E +urn:mavedb:00000044-b-2#7288,NA,NA,p.Leu183Glu,-3.45,-3.53,2,L513E +urn:mavedb:00000044-b-2#7291,NA,NA,p.Leu183Gly,-3.03,-3.05,1,L513G +urn:mavedb:00000044-b-2#7292,NA,NA,p.Leu183Gly,-3.06,-3.05,2,L513G +urn:mavedb:00000044-b-2#7293,NA,NA,p.Leu183His,-3.26,-3.07,1,L513H +urn:mavedb:00000044-b-2#7294,NA,NA,p.Leu183His,-2.87,-3.07,2,L513H +urn:mavedb:00000044-b-2#7295,NA,NA,p.Leu183Ile,-0.52,-0.54,1,L513I +urn:mavedb:00000044-b-2#7296,NA,NA,p.Leu183Ile,-0.57,-0.54,2,L513I +urn:mavedb:00000044-b-2#7297,NA,NA,p.Leu183Lys,-3.4,-3.39,1,L513K +urn:mavedb:00000044-b-2#7298,NA,NA,p.Leu183Lys,-3.39,-3.39,2,L513K +urn:mavedb:00000044-b-2#7299,NA,NA,p.Leu183Met,-0.86,-0.83,1,L513M +urn:mavedb:00000044-b-2#7300,NA,NA,p.Leu183Met,-0.81,-0.83,2,L513M +urn:mavedb:00000044-b-2#7289,NA,NA,p.Leu183Phe,-1.06,-1.08,1,L513F +urn:mavedb:00000044-b-2#7290,NA,NA,p.Leu183Phe,-1.1,-1.08,2,L513F +urn:mavedb:00000044-b-2#7303,NA,NA,p.Leu183Pro,-3.44,-3.43,1,L513P +urn:mavedb:00000044-b-2#7304,NA,NA,p.Leu183Pro,-3.43,-3.43,2,L513P +urn:mavedb:00000044-b-2#7309,NA,NA,p.Leu183Ser,-3.51,-3.43,1,L513S +urn:mavedb:00000044-b-2#7310,NA,NA,p.Leu183Ser,-3.35,-3.43,2,L513S +urn:mavedb:00000044-b-2#7311,NA,NA,p.Leu183Thr,-3.05,-3.04,1,L513T +urn:mavedb:00000044-b-2#7312,NA,NA,p.Leu183Thr,-3.03,-3.04,2,L513T +urn:mavedb:00000044-b-2#7315,NA,NA,p.Leu183Trp,-2.28,-2.56,1,L513W +urn:mavedb:00000044-b-2#7316,NA,NA,p.Leu183Trp,-2.84,-2.56,2,L513W +urn:mavedb:00000044-b-2#7317,NA,NA,p.Leu183Tyr,-2.89,-2.88,1,L513Y +urn:mavedb:00000044-b-2#7318,NA,NA,p.Leu183Tyr,-2.86,-2.88,2,L513Y +urn:mavedb:00000044-b-2#7313,NA,NA,p.Leu183Val,-1.4,-1.56,1,L513V +urn:mavedb:00000044-b-2#7314,NA,NA,p.Leu183Val,-1.72,-1.56,2,L513V +urn:mavedb:00000044-b-2#7479,NA,NA,p.Leu187*,-3.76,-3.28,1,L517 +urn:mavedb:00000044-b-2#7480,NA,NA,p.Leu187*,-2.8,-3.28,2,L517 +urn:mavedb:00000044-b-2#7441,NA,NA,p.Leu187Ala,-2.86,-1.6,1,L517A +urn:mavedb:00000044-b-2#7442,NA,NA,p.Leu187Ala,-0.35,-1.6,2,L517A +urn:mavedb:00000044-b-2#7467,NA,NA,p.Leu187Arg,-0.38,-0.23,1,L517R +urn:mavedb:00000044-b-2#7468,NA,NA,p.Leu187Arg,-0.08,-0.23,2,L517R +urn:mavedb:00000044-b-2#7461,NA,NA,p.Leu187Asn,0.33,0.29,1,L517N +urn:mavedb:00000044-b-2#7462,NA,NA,p.Leu187Asn,0.24,0.29,2,L517N +urn:mavedb:00000044-b-2#7445,NA,NA,p.Leu187Asp,-0.36,-0.25,1,L517D +urn:mavedb:00000044-b-2#7446,NA,NA,p.Leu187Asp,-0.15,-0.25,2,L517D +urn:mavedb:00000044-b-2#7443,NA,NA,p.Leu187Cys,-0.21,-0.46,1,L517C +urn:mavedb:00000044-b-2#7444,NA,NA,p.Leu187Cys,-0.72,-0.46,2,L517C +urn:mavedb:00000044-b-2#7465,NA,NA,p.Leu187Gln,-0.1,-0.03,1,L517Q +urn:mavedb:00000044-b-2#7466,NA,NA,p.Leu187Gln,0.04,-0.03,2,L517Q +urn:mavedb:00000044-b-2#7447,NA,NA,p.Leu187Glu,-0.12,-0.16,1,L517E +urn:mavedb:00000044-b-2#7448,NA,NA,p.Leu187Glu,-0.2,-0.16,2,L517E +urn:mavedb:00000044-b-2#7451,NA,NA,p.Leu187Gly,0.04,0.04,1,L517G +urn:mavedb:00000044-b-2#7452,NA,NA,p.Leu187Gly,NA,0.04,2,L517G +urn:mavedb:00000044-b-2#7453,NA,NA,p.Leu187His,-0.66,-0.36,1,L517H +urn:mavedb:00000044-b-2#7454,NA,NA,p.Leu187His,-0.06,-0.36,2,L517H +urn:mavedb:00000044-b-2#7455,NA,NA,p.Leu187Ile,-0.08,-0.06,1,L517I +urn:mavedb:00000044-b-2#7456,NA,NA,p.Leu187Ile,-0.04,-0.06,2,L517I +urn:mavedb:00000044-b-2#7457,NA,NA,p.Leu187Lys,-0.02,0.04,1,L517K +urn:mavedb:00000044-b-2#7458,NA,NA,p.Leu187Lys,0.1,0.04,2,L517K +urn:mavedb:00000044-b-2#7459,NA,NA,p.Leu187Met,0.11,0.09,1,L517M +urn:mavedb:00000044-b-2#7460,NA,NA,p.Leu187Met,0.07,0.09,2,L517M +urn:mavedb:00000044-b-2#7449,NA,NA,p.Leu187Phe,-0.22,-0.54,1,L517F +urn:mavedb:00000044-b-2#7450,NA,NA,p.Leu187Phe,-0.86,-0.54,2,L517F +urn:mavedb:00000044-b-2#7463,NA,NA,p.Leu187Pro,-0.53,-0.5,1,L517P +urn:mavedb:00000044-b-2#7464,NA,NA,p.Leu187Pro,-0.46,-0.5,2,L517P +urn:mavedb:00000044-b-2#7469,NA,NA,p.Leu187Ser,0.05,-0.01,1,L517S +urn:mavedb:00000044-b-2#7470,NA,NA,p.Leu187Ser,-0.06,-0.01,2,L517S +urn:mavedb:00000044-b-2#7471,NA,NA,p.Leu187Thr,0.2,0.06,1,L517T +urn:mavedb:00000044-b-2#7472,NA,NA,p.Leu187Thr,-0.09,0.06,2,L517T +urn:mavedb:00000044-b-2#7475,NA,NA,p.Leu187Trp,-0.07,-0.61,1,L517W +urn:mavedb:00000044-b-2#7476,NA,NA,p.Leu187Trp,-1.14,-0.61,2,L517W +urn:mavedb:00000044-b-2#7477,NA,NA,p.Leu187Tyr,-0.53,-0.43,1,L517Y +urn:mavedb:00000044-b-2#7478,NA,NA,p.Leu187Tyr,-0.32,-0.43,2,L517Y +urn:mavedb:00000044-b-2#7473,NA,NA,p.Leu187Val,-0.29,-0.33,1,L517V +urn:mavedb:00000044-b-2#7474,NA,NA,p.Leu187Val,-0.38,-0.33,2,L517V +urn:mavedb:00000044-b-2#7519,NA,NA,p.Leu188*,-3.49,-3.56,1,L518 +urn:mavedb:00000044-b-2#7520,NA,NA,p.Leu188*,-3.63,-3.56,2,L518 +urn:mavedb:00000044-b-2#7481,NA,NA,p.Leu188Ala,-0.06,-0.13,1,L518A +urn:mavedb:00000044-b-2#7482,NA,NA,p.Leu188Ala,-0.21,-0.13,2,L518A +urn:mavedb:00000044-b-2#7507,NA,NA,p.Leu188Arg,-0.1,-0.09,1,L518R +urn:mavedb:00000044-b-2#7508,NA,NA,p.Leu188Arg,-0.08,-0.09,2,L518R +urn:mavedb:00000044-b-2#7501,NA,NA,p.Leu188Asn,0.13,0.13,1,L518N +urn:mavedb:00000044-b-2#7502,NA,NA,p.Leu188Asn,0.13,0.13,2,L518N +urn:mavedb:00000044-b-2#7485,NA,NA,p.Leu188Asp,0.39,0.7,1,L518D +urn:mavedb:00000044-b-2#7486,NA,NA,p.Leu188Asp,1,0.7,2,L518D +urn:mavedb:00000044-b-2#7483,NA,NA,p.Leu188Cys,0.11,0.11,1,L518C +urn:mavedb:00000044-b-2#7484,NA,NA,p.Leu188Cys,NA,0.11,2,L518C +urn:mavedb:00000044-b-2#7505,NA,NA,p.Leu188Gln,-0.03,0.06,1,L518Q +urn:mavedb:00000044-b-2#7506,NA,NA,p.Leu188Gln,0.15,0.06,2,L518Q +urn:mavedb:00000044-b-2#7487,NA,NA,p.Leu188Glu,0.66,0.68,1,L518E +urn:mavedb:00000044-b-2#7488,NA,NA,p.Leu188Glu,0.7,0.68,2,L518E +urn:mavedb:00000044-b-2#7491,NA,NA,p.Leu188Gly,0.2,-0.03,1,L518G +urn:mavedb:00000044-b-2#7492,NA,NA,p.Leu188Gly,-0.27,-0.03,2,L518G +urn:mavedb:00000044-b-2#7493,NA,NA,p.Leu188His,-0.24,-0.01,1,L518H +urn:mavedb:00000044-b-2#7494,NA,NA,p.Leu188His,0.22,-0.01,2,L518H +urn:mavedb:00000044-b-2#7495,NA,NA,p.Leu188Ile,-0.17,-0.16,1,L518I +urn:mavedb:00000044-b-2#7496,NA,NA,p.Leu188Ile,-0.16,-0.16,2,L518I +urn:mavedb:00000044-b-2#7497,NA,NA,p.Leu188Lys,0.37,0.35,1,L518K +urn:mavedb:00000044-b-2#7498,NA,NA,p.Leu188Lys,0.32,0.35,2,L518K +urn:mavedb:00000044-b-2#7499,NA,NA,p.Leu188Met,-0.1,-0.08,1,L518M +urn:mavedb:00000044-b-2#7500,NA,NA,p.Leu188Met,-0.07,-0.08,2,L518M +urn:mavedb:00000044-b-2#7489,NA,NA,p.Leu188Phe,-0.19,-0.2,1,L518F +urn:mavedb:00000044-b-2#7490,NA,NA,p.Leu188Phe,-0.22,-0.2,2,L518F +urn:mavedb:00000044-b-2#7503,NA,NA,p.Leu188Pro,-0.02,-0.09,1,L518P +urn:mavedb:00000044-b-2#7504,NA,NA,p.Leu188Pro,-0.17,-0.09,2,L518P +urn:mavedb:00000044-b-2#7509,NA,NA,p.Leu188Ser,0.15,0.29,1,L518S +urn:mavedb:00000044-b-2#7510,NA,NA,p.Leu188Ser,0.44,0.29,2,L518S +urn:mavedb:00000044-b-2#7511,NA,NA,p.Leu188Thr,0.55,0.24,1,L518T 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+urn:mavedb:00000044-b-2#2381,NA,NA,p.Leu60Asn,-0.43,-0.58,1,L390N +urn:mavedb:00000044-b-2#2382,NA,NA,p.Leu60Asn,-0.73,-0.58,2,L390N +urn:mavedb:00000044-b-2#2365,NA,NA,p.Leu60Asp,-0.85,-1,1,L390D +urn:mavedb:00000044-b-2#2366,NA,NA,p.Leu60Asp,-1.15,-1,2,L390D +urn:mavedb:00000044-b-2#2363,NA,NA,p.Leu60Cys,-0.4,-0.43,1,L390C +urn:mavedb:00000044-b-2#2364,NA,NA,p.Leu60Cys,-0.46,-0.43,2,L390C +urn:mavedb:00000044-b-2#2385,NA,NA,p.Leu60Gln,-0.16,-0.16,1,L390Q +urn:mavedb:00000044-b-2#2386,NA,NA,p.Leu60Gln,-0.15,-0.16,2,L390Q +urn:mavedb:00000044-b-2#2367,NA,NA,p.Leu60Glu,-0.69,-0.54,1,L390E +urn:mavedb:00000044-b-2#2368,NA,NA,p.Leu60Glu,-0.39,-0.54,2,L390E +urn:mavedb:00000044-b-2#2371,NA,NA,p.Leu60Gly,-0.61,-0.55,1,L390G +urn:mavedb:00000044-b-2#2372,NA,NA,p.Leu60Gly,-0.5,-0.55,2,L390G +urn:mavedb:00000044-b-2#2373,NA,NA,p.Leu60His,-0.34,-0.29,1,L390H +urn:mavedb:00000044-b-2#2374,NA,NA,p.Leu60His,-0.24,-0.29,2,L390H +urn:mavedb:00000044-b-2#2375,NA,NA,p.Leu60Ile,-0.34,-0.32,1,L390I +urn:mavedb:00000044-b-2#2376,NA,NA,p.Leu60Ile,-0.29,-0.32,2,L390I +urn:mavedb:00000044-b-2#2377,NA,NA,p.Leu60Lys,-0.41,-0.5,1,L390K +urn:mavedb:00000044-b-2#2378,NA,NA,p.Leu60Lys,-0.6,-0.5,2,L390K +urn:mavedb:00000044-b-2#2379,NA,NA,p.Leu60Met,0.02,0.03,1,L390M +urn:mavedb:00000044-b-2#2380,NA,NA,p.Leu60Met,0.04,0.03,2,L390M +urn:mavedb:00000044-b-2#2369,NA,NA,p.Leu60Phe,-0.28,-0.36,1,L390F +urn:mavedb:00000044-b-2#2370,NA,NA,p.Leu60Phe,-0.45,-0.36,2,L390F +urn:mavedb:00000044-b-2#2383,NA,NA,p.Leu60Pro,-1.2,-1.25,1,L390P +urn:mavedb:00000044-b-2#2384,NA,NA,p.Leu60Pro,-1.3,-1.25,2,L390P +urn:mavedb:00000044-b-2#2389,NA,NA,p.Leu60Ser,-0.39,-0.41,1,L390S +urn:mavedb:00000044-b-2#2390,NA,NA,p.Leu60Ser,-0.43,-0.41,2,L390S +urn:mavedb:00000044-b-2#2391,NA,NA,p.Leu60Thr,-0.31,-0.33,1,L390T +urn:mavedb:00000044-b-2#2392,NA,NA,p.Leu60Thr,-0.34,-0.33,2,L390T +urn:mavedb:00000044-b-2#2395,NA,NA,p.Leu60Trp,-0.92,-0.8,1,L390W +urn:mavedb:00000044-b-2#2396,NA,NA,p.Leu60Trp,-0.68,-0.8,2,L390W +urn:mavedb:00000044-b-2#2397,NA,NA,p.Leu60Tyr,0.2,0.2,1,L390Y +urn:mavedb:00000044-b-2#2398,NA,NA,p.Leu60Tyr,0.2,0.2,2,L390Y +urn:mavedb:00000044-b-2#2393,NA,NA,p.Leu60Val,-0.43,-0.42,1,L390V +urn:mavedb:00000044-b-2#2394,NA,NA,p.Leu60Val,-0.4,-0.42,2,L390V +urn:mavedb:00000044-b-2#3799,NA,NA,p.Leu95*,-4.62,-4.58,1,L425 +urn:mavedb:00000044-b-2#3800,NA,NA,p.Leu95*,-4.54,-4.58,2,L425 +urn:mavedb:00000044-b-2#3761,NA,NA,p.Leu95Ala,-2.86,-2.8,1,L425A +urn:mavedb:00000044-b-2#3762,NA,NA,p.Leu95Ala,-2.75,-2.8,2,L425A +urn:mavedb:00000044-b-2#3787,NA,NA,p.Leu95Arg,-2.89,-2.86,1,L425R +urn:mavedb:00000044-b-2#3788,NA,NA,p.Leu95Arg,-2.83,-2.86,2,L425R +urn:mavedb:00000044-b-2#3781,NA,NA,p.Leu95Asn,-2.86,-2.84,1,L425N +urn:mavedb:00000044-b-2#3782,NA,NA,p.Leu95Asn,-2.81,-2.84,2,L425N +urn:mavedb:00000044-b-2#3765,NA,NA,p.Leu95Asp,-2.86,-2.74,1,L425D +urn:mavedb:00000044-b-2#3766,NA,NA,p.Leu95Asp,-2.61,-2.74,2,L425D +urn:mavedb:00000044-b-2#3763,NA,NA,p.Leu95Cys,-2.36,-2.28,1,L425C +urn:mavedb:00000044-b-2#3764,NA,NA,p.Leu95Cys,-2.21,-2.28,2,L425C +urn:mavedb:00000044-b-2#3785,NA,NA,p.Leu95Gln,-2.9,-2.84,1,L425Q +urn:mavedb:00000044-b-2#3786,NA,NA,p.Leu95Gln,-2.77,-2.84,2,L425Q +urn:mavedb:00000044-b-2#3767,NA,NA,p.Leu95Glu,-2.88,-2.86,1,L425E +urn:mavedb:00000044-b-2#3768,NA,NA,p.Leu95Glu,-2.83,-2.86,2,L425E +urn:mavedb:00000044-b-2#3771,NA,NA,p.Leu95Gly,-2.93,-2.84,1,L425G +urn:mavedb:00000044-b-2#3772,NA,NA,p.Leu95Gly,-2.75,-2.84,2,L425G +urn:mavedb:00000044-b-2#3773,NA,NA,p.Leu95His,-2.9,-2.86,1,L425H +urn:mavedb:00000044-b-2#3774,NA,NA,p.Leu95His,-2.82,-2.86,2,L425H +urn:mavedb:00000044-b-2#3775,NA,NA,p.Leu95Ile,-0.37,-0.28,1,L425I +urn:mavedb:00000044-b-2#3776,NA,NA,p.Leu95Ile,-0.19,-0.28,2,L425I +urn:mavedb:00000044-b-2#3777,NA,NA,p.Leu95Lys,-2.91,-2.84,1,L425K +urn:mavedb:00000044-b-2#3778,NA,NA,p.Leu95Lys,-2.77,-2.84,2,L425K +urn:mavedb:00000044-b-2#3779,NA,NA,p.Leu95Met,-0.99,-0.97,1,L425M +urn:mavedb:00000044-b-2#3780,NA,NA,p.Leu95Met,-0.95,-0.97,2,L425M +urn:mavedb:00000044-b-2#3769,NA,NA,p.Leu95Phe,-2.75,-2.67,1,L425F +urn:mavedb:00000044-b-2#3770,NA,NA,p.Leu95Phe,-2.59,-2.67,2,L425F +urn:mavedb:00000044-b-2#3783,NA,NA,p.Leu95Pro,-2.73,-2.73,1,L425P +urn:mavedb:00000044-b-2#3784,NA,NA,p.Leu95Pro,-2.74,-2.73,2,L425P +urn:mavedb:00000044-b-2#3789,NA,NA,p.Leu95Ser,-2.9,-2.82,1,L425S +urn:mavedb:00000044-b-2#3790,NA,NA,p.Leu95Ser,-2.74,-2.82,2,L425S +urn:mavedb:00000044-b-2#3791,NA,NA,p.Leu95Thr,-2.53,-2.5,1,L425T +urn:mavedb:00000044-b-2#3792,NA,NA,p.Leu95Thr,-2.48,-2.5,2,L425T +urn:mavedb:00000044-b-2#3795,NA,NA,p.Leu95Trp,-2.71,-2.72,1,L425W +urn:mavedb:00000044-b-2#3796,NA,NA,p.Leu95Trp,-2.73,-2.72,2,L425W +urn:mavedb:00000044-b-2#3797,NA,NA,p.Leu95Tyr,-2.89,-2.84,1,L425Y +urn:mavedb:00000044-b-2#3798,NA,NA,p.Leu95Tyr,-2.79,-2.84,2,L425Y +urn:mavedb:00000044-b-2#3793,NA,NA,p.Leu95Val,-0.27,-0.28,1,L425V +urn:mavedb:00000044-b-2#3794,NA,NA,p.Leu95Val,-0.28,-0.28,2,L425V +urn:mavedb:00000044-b-2#4559,NA,NA,p.Lys114*,-4.63,-4.56,1,K444 +urn:mavedb:00000044-b-2#4560,NA,NA,p.Lys114*,-4.49,-4.56,2,K444 +urn:mavedb:00000044-b-2#4521,NA,NA,p.Lys114Ala,0.04,-0.02,1,K444A +urn:mavedb:00000044-b-2#4522,NA,NA,p.Lys114Ala,-0.08,-0.02,2,K444A +urn:mavedb:00000044-b-2#4547,NA,NA,p.Lys114Arg,-0.01,-0.09,1,K444R +urn:mavedb:00000044-b-2#4548,NA,NA,p.Lys114Arg,-0.17,-0.09,2,K444R +urn:mavedb:00000044-b-2#4541,NA,NA,p.Lys114Asn,-0.27,-0.19,1,K444N +urn:mavedb:00000044-b-2#4542,NA,NA,p.Lys114Asn,-0.1,-0.19,2,K444N +urn:mavedb:00000044-b-2#4525,NA,NA,p.Lys114Asp,-0.08,-0.08,1,K444D +urn:mavedb:00000044-b-2#4526,NA,NA,p.Lys114Asp,-0.08,-0.08,2,K444D +urn:mavedb:00000044-b-2#4523,NA,NA,p.Lys114Cys,-0.18,-0.22,1,K444C +urn:mavedb:00000044-b-2#4524,NA,NA,p.Lys114Cys,-0.27,-0.22,2,K444C +urn:mavedb:00000044-b-2#4545,NA,NA,p.Lys114Gln,-0.04,-0.09,1,K444Q +urn:mavedb:00000044-b-2#4546,NA,NA,p.Lys114Gln,-0.15,-0.09,2,K444Q +urn:mavedb:00000044-b-2#4527,NA,NA,p.Lys114Glu,0,0.01,1,K444E +urn:mavedb:00000044-b-2#4528,NA,NA,p.Lys114Glu,0.02,0.01,2,K444E +urn:mavedb:00000044-b-2#4531,NA,NA,p.Lys114Gly,-0.18,-0.14,1,K444G +urn:mavedb:00000044-b-2#4532,NA,NA,p.Lys114Gly,-0.11,-0.14,2,K444G +urn:mavedb:00000044-b-2#4533,NA,NA,p.Lys114His,-0.5,-0.31,1,K444H +urn:mavedb:00000044-b-2#4534,NA,NA,p.Lys114His,-0.12,-0.31,2,K444H +urn:mavedb:00000044-b-2#4535,NA,NA,p.Lys114Ile,-0.32,-0.32,1,K444I +urn:mavedb:00000044-b-2#4536,NA,NA,p.Lys114Ile,-0.33,-0.32,2,K444I +urn:mavedb:00000044-b-2#4537,NA,NA,p.Lys114Leu,-0.2,-0.22,1,K444L +urn:mavedb:00000044-b-2#4538,NA,NA,p.Lys114Leu,-0.24,-0.22,2,K444L +urn:mavedb:00000044-b-2#4539,NA,NA,p.Lys114Met,-0.17,-0.24,1,K444M +urn:mavedb:00000044-b-2#4540,NA,NA,p.Lys114Met,-0.31,-0.24,2,K444M +urn:mavedb:00000044-b-2#4529,NA,NA,p.Lys114Phe,-0.27,-0.34,1,K444F +urn:mavedb:00000044-b-2#4530,NA,NA,p.Lys114Phe,-0.41,-0.34,2,K444F +urn:mavedb:00000044-b-2#4543,NA,NA,p.Lys114Pro,-1.05,-0.65,1,K444P +urn:mavedb:00000044-b-2#4544,NA,NA,p.Lys114Pro,-0.26,-0.65,2,K444P +urn:mavedb:00000044-b-2#4549,NA,NA,p.Lys114Ser,-0.02,-0.01,1,K444S +urn:mavedb:00000044-b-2#4550,NA,NA,p.Lys114Ser,-0.01,-0.01,2,K444S +urn:mavedb:00000044-b-2#4551,NA,NA,p.Lys114Thr,0.08,0.07,1,K444T +urn:mavedb:00000044-b-2#4552,NA,NA,p.Lys114Thr,0.06,0.07,2,K444T +urn:mavedb:00000044-b-2#4555,NA,NA,p.Lys114Trp,-0.11,-0.28,1,K444W +urn:mavedb:00000044-b-2#4556,NA,NA,p.Lys114Trp,-0.46,-0.28,2,K444W +urn:mavedb:00000044-b-2#4557,NA,NA,p.Lys114Tyr,-0.62,-0.39,1,K444Y +urn:mavedb:00000044-b-2#4558,NA,NA,p.Lys114Tyr,-0.15,-0.39,2,K444Y +urn:mavedb:00000044-b-2#4553,NA,NA,p.Lys114Val,-0.26,-0.19,1,K444V +urn:mavedb:00000044-b-2#4554,NA,NA,p.Lys114Val,-0.13,-0.19,2,K444V +urn:mavedb:00000044-b-2#5119,NA,NA,p.Lys128*,-4.54,-4.53,1,K458 +urn:mavedb:00000044-b-2#5120,NA,NA,p.Lys128*,-4.52,-4.53,2,K458 +urn:mavedb:00000044-b-2#5081,NA,NA,p.Lys128Ala,-0.18,-0.19,1,K458A +urn:mavedb:00000044-b-2#5082,NA,NA,p.Lys128Ala,-0.2,-0.19,2,K458A +urn:mavedb:00000044-b-2#5107,NA,NA,p.Lys128Arg,-0.12,-0.15,1,K458R +urn:mavedb:00000044-b-2#5108,NA,NA,p.Lys128Arg,-0.17,-0.15,2,K458R +urn:mavedb:00000044-b-2#5101,NA,NA,p.Lys128Asn,-0.13,-0.15,1,K458N +urn:mavedb:00000044-b-2#5102,NA,NA,p.Lys128Asn,-0.17,-0.15,2,K458N +urn:mavedb:00000044-b-2#5085,NA,NA,p.Lys128Asp,-0.21,-0.06,1,K458D +urn:mavedb:00000044-b-2#5086,NA,NA,p.Lys128Asp,0.1,-0.06,2,K458D +urn:mavedb:00000044-b-2#5083,NA,NA,p.Lys128Cys,-0.94,-1.03,1,K458C +urn:mavedb:00000044-b-2#5084,NA,NA,p.Lys128Cys,-1.13,-1.03,2,K458C +urn:mavedb:00000044-b-2#5105,NA,NA,p.Lys128Gln,-0.35,-0.28,1,K458Q +urn:mavedb:00000044-b-2#5106,NA,NA,p.Lys128Gln,-0.22,-0.28,2,K458Q +urn:mavedb:00000044-b-2#5087,NA,NA,p.Lys128Glu,-0.15,-0.08,1,K458E +urn:mavedb:00000044-b-2#5088,NA,NA,p.Lys128Glu,-0.01,-0.08,2,K458E +urn:mavedb:00000044-b-2#5091,NA,NA,p.Lys128Gly,-0.36,-0.28,1,K458G +urn:mavedb:00000044-b-2#5092,NA,NA,p.Lys128Gly,-0.2,-0.28,2,K458G +urn:mavedb:00000044-b-2#5093,NA,NA,p.Lys128His,-0.12,-0.15,1,K458H +urn:mavedb:00000044-b-2#5094,NA,NA,p.Lys128His,-0.19,-0.15,2,K458H +urn:mavedb:00000044-b-2#5095,NA,NA,p.Lys128Ile,-0.63,-0.55,1,K458I +urn:mavedb:00000044-b-2#5096,NA,NA,p.Lys128Ile,-0.47,-0.55,2,K458I +urn:mavedb:00000044-b-2#5097,NA,NA,p.Lys128Leu,-0.59,-0.59,1,K458L +urn:mavedb:00000044-b-2#5098,NA,NA,p.Lys128Leu,-0.6,-0.59,2,K458L +urn:mavedb:00000044-b-2#5099,NA,NA,p.Lys128Met,-0.37,-0.51,1,K458M +urn:mavedb:00000044-b-2#5100,NA,NA,p.Lys128Met,-0.65,-0.51,2,K458M +urn:mavedb:00000044-b-2#5089,NA,NA,p.Lys128Phe,-1.02,-0.92,1,K458F +urn:mavedb:00000044-b-2#5090,NA,NA,p.Lys128Phe,-0.81,-0.92,2,K458F +urn:mavedb:00000044-b-2#5103,NA,NA,p.Lys128Pro,-0.17,-0.17,1,K458P +urn:mavedb:00000044-b-2#5104,NA,NA,p.Lys128Pro,-0.16,-0.17,2,K458P +urn:mavedb:00000044-b-2#5109,NA,NA,p.Lys128Ser,-0.05,-0.05,1,K458S +urn:mavedb:00000044-b-2#5110,NA,NA,p.Lys128Ser,-0.06,-0.05,2,K458S +urn:mavedb:00000044-b-2#5111,NA,NA,p.Lys128Thr,-0.09,-0.14,1,K458T +urn:mavedb:00000044-b-2#5112,NA,NA,p.Lys128Thr,-0.19,-0.14,2,K458T +urn:mavedb:00000044-b-2#5115,NA,NA,p.Lys128Trp,-1.16,-0.96,1,K458W +urn:mavedb:00000044-b-2#5116,NA,NA,p.Lys128Trp,-0.76,-0.96,2,K458W +urn:mavedb:00000044-b-2#5117,NA,NA,p.Lys128Tyr,-0.67,-0.69,1,K458Y +urn:mavedb:00000044-b-2#5118,NA,NA,p.Lys128Tyr,-0.72,-0.69,2,K458Y +urn:mavedb:00000044-b-2#5113,NA,NA,p.Lys128Val,-0.61,-0.51,1,K458V +urn:mavedb:00000044-b-2#5114,NA,NA,p.Lys128Val,-0.4,-0.51,2,K458V +urn:mavedb:00000044-b-2#5279,NA,NA,p.Lys132*,-4.58,-4.57,1,K462 +urn:mavedb:00000044-b-2#5280,NA,NA,p.Lys132*,-4.57,-4.57,2,K462 +urn:mavedb:00000044-b-2#5241,NA,NA,p.Lys132Ala,-0.11,-0.15,1,K462A +urn:mavedb:00000044-b-2#5242,NA,NA,p.Lys132Ala,-0.19,-0.15,2,K462A +urn:mavedb:00000044-b-2#5267,NA,NA,p.Lys132Arg,-0.11,-0.13,1,K462R +urn:mavedb:00000044-b-2#5268,NA,NA,p.Lys132Arg,-0.14,-0.13,2,K462R +urn:mavedb:00000044-b-2#5261,NA,NA,p.Lys132Asn,-0.37,-0.33,1,K462N +urn:mavedb:00000044-b-2#5262,NA,NA,p.Lys132Asn,-0.29,-0.33,2,K462N +urn:mavedb:00000044-b-2#5245,NA,NA,p.Lys132Asp,-0.44,-0.46,1,K462D +urn:mavedb:00000044-b-2#5246,NA,NA,p.Lys132Asp,-0.47,-0.46,2,K462D +urn:mavedb:00000044-b-2#5243,NA,NA,p.Lys132Cys,-0.49,-0.59,1,K462C +urn:mavedb:00000044-b-2#5244,NA,NA,p.Lys132Cys,-0.69,-0.59,2,K462C +urn:mavedb:00000044-b-2#5265,NA,NA,p.Lys132Gln,0,-0.15,1,K462Q +urn:mavedb:00000044-b-2#5266,NA,NA,p.Lys132Gln,-0.29,-0.15,2,K462Q +urn:mavedb:00000044-b-2#5247,NA,NA,p.Lys132Glu,-0.08,-0.03,1,K462E +urn:mavedb:00000044-b-2#5248,NA,NA,p.Lys132Glu,0.02,-0.03,2,K462E +urn:mavedb:00000044-b-2#5251,NA,NA,p.Lys132Gly,-0.31,-0.39,1,K462G +urn:mavedb:00000044-b-2#5252,NA,NA,p.Lys132Gly,-0.47,-0.39,2,K462G +urn:mavedb:00000044-b-2#5253,NA,NA,p.Lys132His,-0.21,-0.21,1,K462H +urn:mavedb:00000044-b-2#5254,NA,NA,p.Lys132His,-0.22,-0.21,2,K462H +urn:mavedb:00000044-b-2#5255,NA,NA,p.Lys132Ile,-0.6,-0.8,1,K462I +urn:mavedb:00000044-b-2#5256,NA,NA,p.Lys132Ile,-1.01,-0.8,2,K462I +urn:mavedb:00000044-b-2#5257,NA,NA,p.Lys132Leu,-0.22,-0.21,1,K462L +urn:mavedb:00000044-b-2#5258,NA,NA,p.Lys132Leu,-0.2,-0.21,2,K462L +urn:mavedb:00000044-b-2#5259,NA,NA,p.Lys132Met,-0.36,-0.26,1,K462M +urn:mavedb:00000044-b-2#5260,NA,NA,p.Lys132Met,-0.16,-0.26,2,K462M +urn:mavedb:00000044-b-2#5249,NA,NA,p.Lys132Phe,-0.67,-0.76,1,K462F +urn:mavedb:00000044-b-2#5250,NA,NA,p.Lys132Phe,-0.85,-0.76,2,K462F +urn:mavedb:00000044-b-2#5263,NA,NA,p.Lys132Pro,-1.09,-1.23,1,K462P +urn:mavedb:00000044-b-2#5264,NA,NA,p.Lys132Pro,-1.37,-1.23,2,K462P +urn:mavedb:00000044-b-2#5269,NA,NA,p.Lys132Ser,-0.26,-0.28,1,K462S +urn:mavedb:00000044-b-2#5270,NA,NA,p.Lys132Ser,-0.29,-0.28,2,K462S +urn:mavedb:00000044-b-2#5271,NA,NA,p.Lys132Thr,-0.35,-0.32,1,K462T +urn:mavedb:00000044-b-2#5272,NA,NA,p.Lys132Thr,-0.3,-0.32,2,K462T +urn:mavedb:00000044-b-2#5275,NA,NA,p.Lys132Trp,-1.93,-1.78,1,K462W +urn:mavedb:00000044-b-2#5276,NA,NA,p.Lys132Trp,-1.63,-1.78,2,K462W +urn:mavedb:00000044-b-2#5277,NA,NA,p.Lys132Tyr,-0.58,-0.63,1,K462Y +urn:mavedb:00000044-b-2#5278,NA,NA,p.Lys132Tyr,-0.68,-0.63,2,K462Y +urn:mavedb:00000044-b-2#5273,NA,NA,p.Lys132Val,-0.87,-0.66,1,K462V +urn:mavedb:00000044-b-2#5274,NA,NA,p.Lys132Val,-0.45,-0.66,2,K462V +urn:mavedb:00000044-b-2#7919,NA,NA,p.Lys198*,-4.59,-4.57,1,K528 +urn:mavedb:00000044-b-2#7920,NA,NA,p.Lys198*,-4.56,-4.57,2,K528 +urn:mavedb:00000044-b-2#7881,NA,NA,p.Lys198Ala,-0.03,0.08,1,K528A +urn:mavedb:00000044-b-2#7882,NA,NA,p.Lys198Ala,0.18,0.08,2,K528A +urn:mavedb:00000044-b-2#7907,NA,NA,p.Lys198Arg,0.04,0.04,1,K528R +urn:mavedb:00000044-b-2#7908,NA,NA,p.Lys198Arg,0.05,0.04,2,K528R +urn:mavedb:00000044-b-2#7901,NA,NA,p.Lys198Asn,0.24,0.18,1,K528N +urn:mavedb:00000044-b-2#7902,NA,NA,p.Lys198Asn,0.12,0.18,2,K528N +urn:mavedb:00000044-b-2#7885,NA,NA,p.Lys198Asp,-0.11,-0.2,1,K528D +urn:mavedb:00000044-b-2#7886,NA,NA,p.Lys198Asp,-0.3,-0.2,2,K528D +urn:mavedb:00000044-b-2#7883,NA,NA,p.Lys198Cys,-0.08,-0.09,1,K528C +urn:mavedb:00000044-b-2#7884,NA,NA,p.Lys198Cys,-0.1,-0.09,2,K528C +urn:mavedb:00000044-b-2#7905,NA,NA,p.Lys198Gln,-0.06,0.04,1,K528Q +urn:mavedb:00000044-b-2#7906,NA,NA,p.Lys198Gln,0.13,0.04,2,K528Q +urn:mavedb:00000044-b-2#7887,NA,NA,p.Lys198Glu,-0.09,0.01,1,K528E +urn:mavedb:00000044-b-2#7888,NA,NA,p.Lys198Glu,0.12,0.01,2,K528E +urn:mavedb:00000044-b-2#7891,NA,NA,p.Lys198Gly,0.18,0.14,1,K528G +urn:mavedb:00000044-b-2#7892,NA,NA,p.Lys198Gly,0.1,0.14,2,K528G +urn:mavedb:00000044-b-2#7893,NA,NA,p.Lys198His,0.05,-0.07,1,K528H +urn:mavedb:00000044-b-2#7894,NA,NA,p.Lys198His,-0.2,-0.07,2,K528H +urn:mavedb:00000044-b-2#7895,NA,NA,p.Lys198Ile,-0.14,-0.09,1,K528I +urn:mavedb:00000044-b-2#7896,NA,NA,p.Lys198Ile,-0.04,-0.09,2,K528I +urn:mavedb:00000044-b-2#7897,NA,NA,p.Lys198Leu,-0.11,-0.1,1,K528L +urn:mavedb:00000044-b-2#7898,NA,NA,p.Lys198Leu,-0.09,-0.1,2,K528L +urn:mavedb:00000044-b-2#7899,NA,NA,p.Lys198Met,-0.03,0,1,K528M +urn:mavedb:00000044-b-2#7900,NA,NA,p.Lys198Met,0.02,0,2,K528M +urn:mavedb:00000044-b-2#7889,NA,NA,p.Lys198Phe,-0.02,-0.22,1,K528F +urn:mavedb:00000044-b-2#7890,NA,NA,p.Lys198Phe,-0.42,-0.22,2,K528F +urn:mavedb:00000044-b-2#7903,NA,NA,p.Lys198Pro,0.04,-0.02,1,K528P +urn:mavedb:00000044-b-2#7904,NA,NA,p.Lys198Pro,-0.09,-0.02,2,K528P +urn:mavedb:00000044-b-2#7909,NA,NA,p.Lys198Ser,0.06,0.04,1,K528S +urn:mavedb:00000044-b-2#7910,NA,NA,p.Lys198Ser,0.01,0.04,2,K528S +urn:mavedb:00000044-b-2#7911,NA,NA,p.Lys198Thr,-0.06,-0.07,1,K528T +urn:mavedb:00000044-b-2#7912,NA,NA,p.Lys198Thr,-0.07,-0.07,2,K528T +urn:mavedb:00000044-b-2#7915,NA,NA,p.Lys198Trp,-0.06,-0.09,1,K528W +urn:mavedb:00000044-b-2#7916,NA,NA,p.Lys198Trp,-0.11,-0.09,2,K528W +urn:mavedb:00000044-b-2#7917,NA,NA,p.Lys198Tyr,-0.05,-0.08,1,K528Y +urn:mavedb:00000044-b-2#7918,NA,NA,p.Lys198Tyr,-0.11,-0.08,2,K528Y +urn:mavedb:00000044-b-2#7913,NA,NA,p.Lys198Val,-0.02,-0.1,1,K528V +urn:mavedb:00000044-b-2#7914,NA,NA,p.Lys198Val,-0.18,-0.1,2,K528V +urn:mavedb:00000044-b-2#7959,NA,NA,p.Lys199*,-4.62,-4.56,1,K529 +urn:mavedb:00000044-b-2#7960,NA,NA,p.Lys199*,-4.51,-4.56,2,K529 +urn:mavedb:00000044-b-2#7921,NA,NA,p.Lys199Ala,0.76,0.38,1,K529A +urn:mavedb:00000044-b-2#7922,NA,NA,p.Lys199Ala,0.01,0.38,2,K529A +urn:mavedb:00000044-b-2#7947,NA,NA,p.Lys199Arg,-0.08,0.07,1,K529R +urn:mavedb:00000044-b-2#7948,NA,NA,p.Lys199Arg,0.22,0.07,2,K529R +urn:mavedb:00000044-b-2#7941,NA,NA,p.Lys199Asn,0.08,0.02,1,K529N +urn:mavedb:00000044-b-2#7942,NA,NA,p.Lys199Asn,-0.03,0.02,2,K529N +urn:mavedb:00000044-b-2#7925,NA,NA,p.Lys199Asp,-0.02,0,1,K529D +urn:mavedb:00000044-b-2#7926,NA,NA,p.Lys199Asp,0.01,0,2,K529D +urn:mavedb:00000044-b-2#7923,NA,NA,p.Lys199Cys,0.11,0.11,1,K529C +urn:mavedb:00000044-b-2#7924,NA,NA,p.Lys199Cys,0.11,0.11,2,K529C +urn:mavedb:00000044-b-2#7945,NA,NA,p.Lys199Gln,-0.04,0.03,1,K529Q +urn:mavedb:00000044-b-2#7946,NA,NA,p.Lys199Gln,0.1,0.03,2,K529Q +urn:mavedb:00000044-b-2#7927,NA,NA,p.Lys199Glu,-0.1,-0.06,1,K529E +urn:mavedb:00000044-b-2#7928,NA,NA,p.Lys199Glu,-0.02,-0.06,2,K529E +urn:mavedb:00000044-b-2#7931,NA,NA,p.Lys199Gly,0.08,0.22,1,K529G +urn:mavedb:00000044-b-2#7932,NA,NA,p.Lys199Gly,0.36,0.22,2,K529G +urn:mavedb:00000044-b-2#7933,NA,NA,p.Lys199His,0.11,0.16,1,K529H +urn:mavedb:00000044-b-2#7934,NA,NA,p.Lys199His,0.2,0.16,2,K529H +urn:mavedb:00000044-b-2#7935,NA,NA,p.Lys199Ile,0.08,0.05,1,K529I +urn:mavedb:00000044-b-2#7936,NA,NA,p.Lys199Ile,0.02,0.05,2,K529I +urn:mavedb:00000044-b-2#7937,NA,NA,p.Lys199Leu,0.03,0,1,K529L +urn:mavedb:00000044-b-2#7938,NA,NA,p.Lys199Leu,-0.04,0,2,K529L 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+urn:mavedb:00000044-b-2#1024,NA,NA,p.Lys26Pro,-2.81,-2.76,2,K356P +urn:mavedb:00000044-b-2#1029,NA,NA,p.Lys26Ser,-0.47,-0.49,1,K356S +urn:mavedb:00000044-b-2#1030,NA,NA,p.Lys26Ser,-0.51,-0.49,2,K356S +urn:mavedb:00000044-b-2#1031,NA,NA,p.Lys26Thr,0.01,0.14,1,K356T +urn:mavedb:00000044-b-2#1032,NA,NA,p.Lys26Thr,0.28,0.14,2,K356T +urn:mavedb:00000044-b-2#1035,NA,NA,p.Lys26Trp,-1.36,-1.41,1,K356W +urn:mavedb:00000044-b-2#1036,NA,NA,p.Lys26Trp,-1.46,-1.41,2,K356W +urn:mavedb:00000044-b-2#1037,NA,NA,p.Lys26Tyr,-0.79,-0.85,1,K356Y +urn:mavedb:00000044-b-2#1038,NA,NA,p.Lys26Tyr,-0.92,-0.85,2,K356Y +urn:mavedb:00000044-b-2#1033,NA,NA,p.Lys26Val,0,0.04,1,K356V +urn:mavedb:00000044-b-2#1034,NA,NA,p.Lys26Val,0.08,0.04,2,K356V +urn:mavedb:00000044-b-2#1919,NA,NA,p.Lys48*,-4.58,-4.53,1,K378 +urn:mavedb:00000044-b-2#1920,NA,NA,p.Lys48*,-4.49,-4.53,2,K378 +urn:mavedb:00000044-b-2#1881,NA,NA,p.Lys48Ala,-0.38,-0.41,1,K378A +urn:mavedb:00000044-b-2#1882,NA,NA,p.Lys48Ala,-0.43,-0.41,2,K378A +urn:mavedb:00000044-b-2#1907,NA,NA,p.Lys48Arg,0.07,0.16,1,K378R +urn:mavedb:00000044-b-2#1908,NA,NA,p.Lys48Arg,0.24,0.16,2,K378R +urn:mavedb:00000044-b-2#1901,NA,NA,p.Lys48Asn,-0.29,-0.26,1,K378N +urn:mavedb:00000044-b-2#1902,NA,NA,p.Lys48Asn,-0.23,-0.26,2,K378N +urn:mavedb:00000044-b-2#1885,NA,NA,p.Lys48Asp,-0.21,-0.29,1,K378D +urn:mavedb:00000044-b-2#1886,NA,NA,p.Lys48Asp,-0.37,-0.29,2,K378D +urn:mavedb:00000044-b-2#1883,NA,NA,p.Lys48Cys,-0.65,-0.71,1,K378C +urn:mavedb:00000044-b-2#1884,NA,NA,p.Lys48Cys,-0.76,-0.71,2,K378C +urn:mavedb:00000044-b-2#1905,NA,NA,p.Lys48Gln,-0.11,-0.11,1,K378Q +urn:mavedb:00000044-b-2#1906,NA,NA,p.Lys48Gln,-0.11,-0.11,2,K378Q +urn:mavedb:00000044-b-2#1887,NA,NA,p.Lys48Glu,-0.11,-0.09,1,K378E +urn:mavedb:00000044-b-2#1888,NA,NA,p.Lys48Glu,-0.08,-0.09,2,K378E +urn:mavedb:00000044-b-2#1891,NA,NA,p.Lys48Gly,-2.55,-2.48,1,K378G +urn:mavedb:00000044-b-2#1892,NA,NA,p.Lys48Gly,-2.41,-2.48,2,K378G +urn:mavedb:00000044-b-2#1893,NA,NA,p.Lys48His,-0.79,-0.68,1,K378H +urn:mavedb:00000044-b-2#1894,NA,NA,p.Lys48His,-0.57,-0.68,2,K378H +urn:mavedb:00000044-b-2#1895,NA,NA,p.Lys48Ile,-0.32,-0.35,1,K378I +urn:mavedb:00000044-b-2#1896,NA,NA,p.Lys48Ile,-0.37,-0.35,2,K378I +urn:mavedb:00000044-b-2#1897,NA,NA,p.Lys48Leu,-0.44,-0.51,1,K378L +urn:mavedb:00000044-b-2#1898,NA,NA,p.Lys48Leu,-0.58,-0.51,2,K378L +urn:mavedb:00000044-b-2#1899,NA,NA,p.Lys48Met,-0.76,-0.65,1,K378M +urn:mavedb:00000044-b-2#1900,NA,NA,p.Lys48Met,-0.55,-0.65,2,K378M +urn:mavedb:00000044-b-2#1889,NA,NA,p.Lys48Phe,-1.49,-1.57,1,K378F +urn:mavedb:00000044-b-2#1890,NA,NA,p.Lys48Phe,-1.65,-1.57,2,K378F +urn:mavedb:00000044-b-2#1903,NA,NA,p.Lys48Pro,-2.82,-2.77,1,K378P +urn:mavedb:00000044-b-2#1904,NA,NA,p.Lys48Pro,-2.73,-2.77,2,K378P +urn:mavedb:00000044-b-2#1909,NA,NA,p.Lys48Ser,-0.6,-0.52,1,K378S +urn:mavedb:00000044-b-2#1910,NA,NA,p.Lys48Ser,-0.45,-0.52,2,K378S +urn:mavedb:00000044-b-2#1911,NA,NA,p.Lys48Thr,-0.68,-0.51,1,K378T +urn:mavedb:00000044-b-2#1912,NA,NA,p.Lys48Thr,-0.34,-0.51,2,K378T +urn:mavedb:00000044-b-2#1915,NA,NA,p.Lys48Trp,-2.04,-1.96,1,K378W +urn:mavedb:00000044-b-2#1916,NA,NA,p.Lys48Trp,-1.88,-1.96,2,K378W +urn:mavedb:00000044-b-2#1917,NA,NA,p.Lys48Tyr,-1.18,-1.31,1,K378Y +urn:mavedb:00000044-b-2#1918,NA,NA,p.Lys48Tyr,-1.45,-1.31,2,K378Y +urn:mavedb:00000044-b-2#1913,NA,NA,p.Lys48Val,-0.34,-0.42,1,K378V +urn:mavedb:00000044-b-2#1914,NA,NA,p.Lys48Val,-0.5,-0.42,2,K378V +urn:mavedb:00000044-b-2#2239,NA,NA,p.Lys56*,-4.59,-4.57,1,K386 +urn:mavedb:00000044-b-2#2240,NA,NA,p.Lys56*,-4.55,-4.57,2,K386 +urn:mavedb:00000044-b-2#2201,NA,NA,p.Lys56Ala,0.1,0.05,1,K386A +urn:mavedb:00000044-b-2#2202,NA,NA,p.Lys56Ala,0.01,0.05,2,K386A +urn:mavedb:00000044-b-2#2227,NA,NA,p.Lys56Arg,-0.13,-0.13,1,K386R +urn:mavedb:00000044-b-2#2228,NA,NA,p.Lys56Arg,-0.13,-0.13,2,K386R +urn:mavedb:00000044-b-2#2221,NA,NA,p.Lys56Asn,-0.08,-0.13,1,K386N +urn:mavedb:00000044-b-2#2222,NA,NA,p.Lys56Asn,-0.17,-0.13,2,K386N +urn:mavedb:00000044-b-2#2205,NA,NA,p.Lys56Asp,0.11,0.15,1,K386D +urn:mavedb:00000044-b-2#2206,NA,NA,p.Lys56Asp,0.18,0.15,2,K386D +urn:mavedb:00000044-b-2#2203,NA,NA,p.Lys56Cys,-0.52,-0.43,1,K386C +urn:mavedb:00000044-b-2#2204,NA,NA,p.Lys56Cys,-0.34,-0.43,2,K386C +urn:mavedb:00000044-b-2#2225,NA,NA,p.Lys56Gln,0.16,0.09,1,K386Q +urn:mavedb:00000044-b-2#2226,NA,NA,p.Lys56Gln,0.03,0.09,2,K386Q +urn:mavedb:00000044-b-2#2207,NA,NA,p.Lys56Glu,0.19,0.18,1,K386E +urn:mavedb:00000044-b-2#2208,NA,NA,p.Lys56Glu,0.17,0.18,2,K386E +urn:mavedb:00000044-b-2#2211,NA,NA,p.Lys56Gly,-0.26,-0.21,1,K386G +urn:mavedb:00000044-b-2#2212,NA,NA,p.Lys56Gly,-0.17,-0.21,2,K386G +urn:mavedb:00000044-b-2#2213,NA,NA,p.Lys56His,-0.11,-0.12,1,K386H +urn:mavedb:00000044-b-2#2214,NA,NA,p.Lys56His,-0.13,-0.12,2,K386H +urn:mavedb:00000044-b-2#2215,NA,NA,p.Lys56Ile,-0.56,-0.43,1,K386I +urn:mavedb:00000044-b-2#2216,NA,NA,p.Lys56Ile,-0.29,-0.43,2,K386I +urn:mavedb:00000044-b-2#2217,NA,NA,p.Lys56Leu,-0.47,-0.4,1,K386L +urn:mavedb:00000044-b-2#2218,NA,NA,p.Lys56Leu,-0.33,-0.4,2,K386L +urn:mavedb:00000044-b-2#2219,NA,NA,p.Lys56Met,-0.18,-0.14,1,K386M +urn:mavedb:00000044-b-2#2220,NA,NA,p.Lys56Met,-0.1,-0.14,2,K386M +urn:mavedb:00000044-b-2#2209,NA,NA,p.Lys56Phe,-0.97,-1.06,1,K386F +urn:mavedb:00000044-b-2#2210,NA,NA,p.Lys56Phe,-1.15,-1.06,2,K386F +urn:mavedb:00000044-b-2#2223,NA,NA,p.Lys56Pro,-1.66,-1.77,1,K386P +urn:mavedb:00000044-b-2#2224,NA,NA,p.Lys56Pro,-1.89,-1.77,2,K386P +urn:mavedb:00000044-b-2#2229,NA,NA,p.Lys56Ser,-0.06,-0.04,1,K386S +urn:mavedb:00000044-b-2#2230,NA,NA,p.Lys56Ser,-0.03,-0.04,2,K386S +urn:mavedb:00000044-b-2#2231,NA,NA,p.Lys56Thr,-0.11,-0.1,1,K386T +urn:mavedb:00000044-b-2#2232,NA,NA,p.Lys56Thr,-0.09,-0.1,2,K386T +urn:mavedb:00000044-b-2#2235,NA,NA,p.Lys56Trp,-1.69,-1.5,1,K386W +urn:mavedb:00000044-b-2#2236,NA,NA,p.Lys56Trp,-1.31,-1.5,2,K386W +urn:mavedb:00000044-b-2#2237,NA,NA,p.Lys56Tyr,-0.66,-0.75,1,K386Y +urn:mavedb:00000044-b-2#2238,NA,NA,p.Lys56Tyr,-0.84,-0.75,2,K386Y +urn:mavedb:00000044-b-2#2233,NA,NA,p.Lys56Val,-0.45,-0.44,1,K386V +urn:mavedb:00000044-b-2#2234,NA,NA,p.Lys56Val,-0.44,-0.44,2,K386V +urn:mavedb:00000044-b-2#3479,NA,NA,p.Lys87*,-4.62,-4.58,1,K417 +urn:mavedb:00000044-b-2#3480,NA,NA,p.Lys87*,-4.54,-4.58,2,K417 +urn:mavedb:00000044-b-2#3441,NA,NA,p.Lys87Ala,-0.02,0.03,1,K417A +urn:mavedb:00000044-b-2#3442,NA,NA,p.Lys87Ala,0.08,0.03,2,K417A +urn:mavedb:00000044-b-2#3467,NA,NA,p.Lys87Arg,0.08,0.08,1,K417R +urn:mavedb:00000044-b-2#3468,NA,NA,p.Lys87Arg,0.08,0.08,2,K417R +urn:mavedb:00000044-b-2#3461,NA,NA,p.Lys87Asn,0.14,0.1,1,K417N +urn:mavedb:00000044-b-2#3462,NA,NA,p.Lys87Asn,0.06,0.1,2,K417N +urn:mavedb:00000044-b-2#3445,NA,NA,p.Lys87Asp,-0.27,-0.33,1,K417D +urn:mavedb:00000044-b-2#3446,NA,NA,p.Lys87Asp,-0.39,-0.33,2,K417D +urn:mavedb:00000044-b-2#3443,NA,NA,p.Lys87Cys,-0.05,-0.05,1,K417C +urn:mavedb:00000044-b-2#3444,NA,NA,p.Lys87Cys,-0.05,-0.05,2,K417C +urn:mavedb:00000044-b-2#3465,NA,NA,p.Lys87Gln,-0.07,-0.05,1,K417Q +urn:mavedb:00000044-b-2#3466,NA,NA,p.Lys87Gln,-0.03,-0.05,2,K417Q +urn:mavedb:00000044-b-2#3447,NA,NA,p.Lys87Glu,-0.29,-0.25,1,K417E +urn:mavedb:00000044-b-2#3448,NA,NA,p.Lys87Glu,-0.21,-0.25,2,K417E +urn:mavedb:00000044-b-2#3451,NA,NA,p.Lys87Gly,-0.28,-0.27,1,K417G +urn:mavedb:00000044-b-2#3452,NA,NA,p.Lys87Gly,-0.26,-0.27,2,K417G +urn:mavedb:00000044-b-2#3453,NA,NA,p.Lys87His,0.01,0.1,1,K417H +urn:mavedb:00000044-b-2#3454,NA,NA,p.Lys87His,0.18,0.1,2,K417H +urn:mavedb:00000044-b-2#3455,NA,NA,p.Lys87Ile,0.39,0.39,1,K417I +urn:mavedb:00000044-b-2#3456,NA,NA,p.Lys87Ile,0.38,0.39,2,K417I +urn:mavedb:00000044-b-2#3457,NA,NA,p.Lys87Leu,0.09,0.17,1,K417L +urn:mavedb:00000044-b-2#3458,NA,NA,p.Lys87Leu,0.26,0.17,2,K417L +urn:mavedb:00000044-b-2#3459,NA,NA,p.Lys87Met,0.03,0.06,1,K417M +urn:mavedb:00000044-b-2#3460,NA,NA,p.Lys87Met,0.09,0.06,2,K417M +urn:mavedb:00000044-b-2#3449,NA,NA,p.Lys87Phe,-0.11,-0.11,1,K417F +urn:mavedb:00000044-b-2#3450,NA,NA,p.Lys87Phe,-0.1,-0.11,2,K417F +urn:mavedb:00000044-b-2#3463,NA,NA,p.Lys87Pro,0.05,0,1,K417P +urn:mavedb:00000044-b-2#3464,NA,NA,p.Lys87Pro,-0.05,0,2,K417P +urn:mavedb:00000044-b-2#3469,NA,NA,p.Lys87Ser,-0.06,-0.05,1,K417S +urn:mavedb:00000044-b-2#3470,NA,NA,p.Lys87Ser,-0.04,-0.05,2,K417S +urn:mavedb:00000044-b-2#3471,NA,NA,p.Lys87Thr,0.22,0.25,1,K417T +urn:mavedb:00000044-b-2#3472,NA,NA,p.Lys87Thr,0.28,0.25,2,K417T +urn:mavedb:00000044-b-2#3475,NA,NA,p.Lys87Trp,-0.29,-0.28,1,K417W +urn:mavedb:00000044-b-2#3476,NA,NA,p.Lys87Trp,-0.26,-0.28,2,K417W +urn:mavedb:00000044-b-2#3477,NA,NA,p.Lys87Tyr,0,0.07,1,K417Y +urn:mavedb:00000044-b-2#3478,NA,NA,p.Lys87Tyr,0.13,0.07,2,K417Y +urn:mavedb:00000044-b-2#3473,NA,NA,p.Lys87Val,0.63,0.65,1,K417V +urn:mavedb:00000044-b-2#3474,NA,NA,p.Lys87Val,0.67,0.65,2,K417V +urn:mavedb:00000044-b-2#3759,NA,NA,p.Lys94*,-4.58,-4.57,1,K424 +urn:mavedb:00000044-b-2#3760,NA,NA,p.Lys94*,-4.55,-4.57,2,K424 +urn:mavedb:00000044-b-2#3721,NA,NA,p.Lys94Ala,-1.39,-1.45,1,K424A +urn:mavedb:00000044-b-2#3722,NA,NA,p.Lys94Ala,-1.51,-1.45,2,K424A +urn:mavedb:00000044-b-2#3747,NA,NA,p.Lys94Arg,-0.55,-0.63,1,K424R +urn:mavedb:00000044-b-2#3748,NA,NA,p.Lys94Arg,-0.71,-0.63,2,K424R +urn:mavedb:00000044-b-2#3741,NA,NA,p.Lys94Asn,-1.6,-1.58,1,K424N +urn:mavedb:00000044-b-2#3742,NA,NA,p.Lys94Asn,-1.57,-1.58,2,K424N +urn:mavedb:00000044-b-2#3725,NA,NA,p.Lys94Asp,-2.75,-2.74,1,K424D +urn:mavedb:00000044-b-2#3726,NA,NA,p.Lys94Asp,-2.73,-2.74,2,K424D +urn:mavedb:00000044-b-2#3723,NA,NA,p.Lys94Cys,-1.52,-1.64,1,K424C +urn:mavedb:00000044-b-2#3724,NA,NA,p.Lys94Cys,-1.76,-1.64,2,K424C +urn:mavedb:00000044-b-2#3745,NA,NA,p.Lys94Gln,-2.17,-2.07,1,K424Q +urn:mavedb:00000044-b-2#3746,NA,NA,p.Lys94Gln,-1.97,-2.07,2,K424Q +urn:mavedb:00000044-b-2#3727,NA,NA,p.Lys94Glu,-2.84,-2.68,1,K424E +urn:mavedb:00000044-b-2#3728,NA,NA,p.Lys94Glu,-2.52,-2.68,2,K424E +urn:mavedb:00000044-b-2#3731,NA,NA,p.Lys94Gly,-2.59,-2.48,1,K424G +urn:mavedb:00000044-b-2#3732,NA,NA,p.Lys94Gly,-2.38,-2.48,2,K424G +urn:mavedb:00000044-b-2#3733,NA,NA,p.Lys94His,-0.73,-0.65,1,K424H +urn:mavedb:00000044-b-2#3734,NA,NA,p.Lys94His,-0.56,-0.65,2,K424H +urn:mavedb:00000044-b-2#3735,NA,NA,p.Lys94Ile,-2.74,-2.58,1,K424I +urn:mavedb:00000044-b-2#3736,NA,NA,p.Lys94Ile,-2.42,-2.58,2,K424I +urn:mavedb:00000044-b-2#3737,NA,NA,p.Lys94Leu,-2.64,-2.59,1,K424L +urn:mavedb:00000044-b-2#3738,NA,NA,p.Lys94Leu,-2.55,-2.59,2,K424L +urn:mavedb:00000044-b-2#3739,NA,NA,p.Lys94Met,-2.26,-2.23,1,K424M +urn:mavedb:00000044-b-2#3740,NA,NA,p.Lys94Met,-2.19,-2.23,2,K424M +urn:mavedb:00000044-b-2#3729,NA,NA,p.Lys94Phe,-2.76,-2.7,1,K424F +urn:mavedb:00000044-b-2#3730,NA,NA,p.Lys94Phe,-2.65,-2.7,2,K424F +urn:mavedb:00000044-b-2#3743,NA,NA,p.Lys94Pro,-2.96,-2.87,1,K424P +urn:mavedb:00000044-b-2#3744,NA,NA,p.Lys94Pro,-2.77,-2.87,2,K424P +urn:mavedb:00000044-b-2#3749,NA,NA,p.Lys94Ser,-1.92,-1.87,1,K424S +urn:mavedb:00000044-b-2#3750,NA,NA,p.Lys94Ser,-1.82,-1.87,2,K424S +urn:mavedb:00000044-b-2#3751,NA,NA,p.Lys94Thr,-2.05,-2.05,1,K424T +urn:mavedb:00000044-b-2#3752,NA,NA,p.Lys94Thr,-2.04,-2.05,2,K424T +urn:mavedb:00000044-b-2#3755,NA,NA,p.Lys94Trp,-2.87,-2.82,1,K424W +urn:mavedb:00000044-b-2#3756,NA,NA,p.Lys94Trp,-2.76,-2.82,2,K424W +urn:mavedb:00000044-b-2#3757,NA,NA,p.Lys94Tyr,-2.51,-2.46,1,K424Y +urn:mavedb:00000044-b-2#3758,NA,NA,p.Lys94Tyr,-2.41,-2.46,2,K424Y +urn:mavedb:00000044-b-2#3753,NA,NA,p.Lys94Val,-2.36,-2.37,1,K424V +urn:mavedb:00000044-b-2#3754,NA,NA,p.Lys94Val,-2.38,-2.37,2,K424V +urn:mavedb:00000044-b-2#479,NA,NA,p.Phe12*,-4.63,-4.6,1,F342 +urn:mavedb:00000044-b-2#480,NA,NA,p.Phe12*,-4.56,-4.6,2,F342 +urn:mavedb:00000044-b-2#5039,NA,NA,p.Phe126*,-3.74,-3.89,1,F456 +urn:mavedb:00000044-b-2#5040,NA,NA,p.Phe126*,-4.04,-3.89,2,F456 +urn:mavedb:00000044-b-2#5001,NA,NA,p.Phe126Ala,-0.21,-0.1,1,F456A +urn:mavedb:00000044-b-2#5002,NA,NA,p.Phe126Ala,0.02,-0.1,2,F456A +urn:mavedb:00000044-b-2#5027,NA,NA,p.Phe126Arg,-0.07,-0.11,1,F456R +urn:mavedb:00000044-b-2#5028,NA,NA,p.Phe126Arg,-0.14,-0.11,2,F456R +urn:mavedb:00000044-b-2#5021,NA,NA,p.Phe126Asn,-0.11,-0.1,1,F456N +urn:mavedb:00000044-b-2#5022,NA,NA,p.Phe126Asn,-0.1,-0.1,2,F456N +urn:mavedb:00000044-b-2#5005,NA,NA,p.Phe126Asp,-0.11,-0.69,1,F456D +urn:mavedb:00000044-b-2#5006,NA,NA,p.Phe126Asp,-1.28,-0.69,2,F456D +urn:mavedb:00000044-b-2#5003,NA,NA,p.Phe126Cys,-0.2,-0.29,1,F456C +urn:mavedb:00000044-b-2#5004,NA,NA,p.Phe126Cys,-0.37,-0.29,2,F456C +urn:mavedb:00000044-b-2#5025,NA,NA,p.Phe126Gln,-0.49,-0.35,1,F456Q +urn:mavedb:00000044-b-2#5026,NA,NA,p.Phe126Gln,-0.22,-0.35,2,F456Q +urn:mavedb:00000044-b-2#5007,NA,NA,p.Phe126Glu,-0.46,-0.41,1,F456E +urn:mavedb:00000044-b-2#5008,NA,NA,p.Phe126Glu,-0.35,-0.41,2,F456E +urn:mavedb:00000044-b-2#5009,NA,NA,p.Phe126Gly,-0.11,-0.19,1,F456G +urn:mavedb:00000044-b-2#5010,NA,NA,p.Phe126Gly,-0.27,-0.19,2,F456G +urn:mavedb:00000044-b-2#5011,NA,NA,p.Phe126His,-0.01,0.11,1,F456H +urn:mavedb:00000044-b-2#5012,NA,NA,p.Phe126His,0.22,0.11,2,F456H +urn:mavedb:00000044-b-2#5013,NA,NA,p.Phe126Ile,-0.12,-0.15,1,F456I +urn:mavedb:00000044-b-2#5014,NA,NA,p.Phe126Ile,-0.18,-0.15,2,F456I +urn:mavedb:00000044-b-2#5017,NA,NA,p.Phe126Leu,-0.4,-0.49,1,F456L +urn:mavedb:00000044-b-2#5018,NA,NA,p.Phe126Leu,-0.58,-0.49,2,F456L +urn:mavedb:00000044-b-2#5015,NA,NA,p.Phe126Lys,-0.19,-0.17,1,F456K +urn:mavedb:00000044-b-2#5016,NA,NA,p.Phe126Lys,-0.14,-0.17,2,F456K +urn:mavedb:00000044-b-2#5019,NA,NA,p.Phe126Met,-0.21,-0.37,1,F456M +urn:mavedb:00000044-b-2#5020,NA,NA,p.Phe126Met,-0.53,-0.37,2,F456M +urn:mavedb:00000044-b-2#5023,NA,NA,p.Phe126Pro,-2.6,-2.53,1,F456P +urn:mavedb:00000044-b-2#5024,NA,NA,p.Phe126Pro,-2.45,-2.53,2,F456P +urn:mavedb:00000044-b-2#5029,NA,NA,p.Phe126Ser,-0.31,-0.35,1,F456S +urn:mavedb:00000044-b-2#5030,NA,NA,p.Phe126Ser,-0.39,-0.35,2,F456S +urn:mavedb:00000044-b-2#5031,NA,NA,p.Phe126Thr,-0.36,-0.26,1,F456T +urn:mavedb:00000044-b-2#5032,NA,NA,p.Phe126Thr,-0.17,-0.26,2,F456T +urn:mavedb:00000044-b-2#5035,NA,NA,p.Phe126Trp,-0.1,-0.04,1,F456W +urn:mavedb:00000044-b-2#5036,NA,NA,p.Phe126Trp,0.01,-0.04,2,F456W +urn:mavedb:00000044-b-2#5037,NA,NA,p.Phe126Tyr,0.51,0.48,1,F456Y +urn:mavedb:00000044-b-2#5038,NA,NA,p.Phe126Tyr,0.45,0.48,2,F456Y +urn:mavedb:00000044-b-2#5033,NA,NA,p.Phe126Val,-0.25,-0.16,1,F456V +urn:mavedb:00000044-b-2#5034,NA,NA,p.Phe126Val,-0.08,-0.16,2,F456V +urn:mavedb:00000044-b-2#441,NA,NA,p.Phe12Ala,-2.26,-2.24,1,F342A +urn:mavedb:00000044-b-2#442,NA,NA,p.Phe12Ala,-2.21,-2.24,2,F342A +urn:mavedb:00000044-b-2#467,NA,NA,p.Phe12Arg,-2.4,-2.43,1,F342R +urn:mavedb:00000044-b-2#468,NA,NA,p.Phe12Arg,-2.46,-2.43,2,F342R +urn:mavedb:00000044-b-2#461,NA,NA,p.Phe12Asn,-2.51,-2.39,1,F342N +urn:mavedb:00000044-b-2#462,NA,NA,p.Phe12Asn,-2.27,-2.39,2,F342N +urn:mavedb:00000044-b-2#445,NA,NA,p.Phe12Asp,-2.57,-2.54,1,F342D +urn:mavedb:00000044-b-2#446,NA,NA,p.Phe12Asp,-2.51,-2.54,2,F342D +urn:mavedb:00000044-b-2#443,NA,NA,p.Phe12Cys,-2.3,-2.27,1,F342C +urn:mavedb:00000044-b-2#444,NA,NA,p.Phe12Cys,-2.25,-2.27,2,F342C +urn:mavedb:00000044-b-2#465,NA,NA,p.Phe12Gln,-2.42,-2.33,1,F342Q +urn:mavedb:00000044-b-2#466,NA,NA,p.Phe12Gln,-2.25,-2.33,2,F342Q +urn:mavedb:00000044-b-2#447,NA,NA,p.Phe12Glu,-2.65,-2.59,1,F342E +urn:mavedb:00000044-b-2#448,NA,NA,p.Phe12Glu,-2.53,-2.59,2,F342E +urn:mavedb:00000044-b-2#449,NA,NA,p.Phe12Gly,-2.39,-2.36,1,F342G +urn:mavedb:00000044-b-2#450,NA,NA,p.Phe12Gly,-2.33,-2.36,2,F342G +urn:mavedb:00000044-b-2#451,NA,NA,p.Phe12His,-2.36,-2.32,1,F342H +urn:mavedb:00000044-b-2#452,NA,NA,p.Phe12His,-2.28,-2.32,2,F342H +urn:mavedb:00000044-b-2#453,NA,NA,p.Phe12Ile,-0.69,-0.78,1,F342I +urn:mavedb:00000044-b-2#454,NA,NA,p.Phe12Ile,-0.86,-0.78,2,F342I +urn:mavedb:00000044-b-2#457,NA,NA,p.Phe12Leu,-0.87,-0.84,1,F342L +urn:mavedb:00000044-b-2#458,NA,NA,p.Phe12Leu,-0.81,-0.84,2,F342L +urn:mavedb:00000044-b-2#455,NA,NA,p.Phe12Lys,-2.34,-2.23,1,F342K +urn:mavedb:00000044-b-2#456,NA,NA,p.Phe12Lys,-2.11,-2.23,2,F342K +urn:mavedb:00000044-b-2#459,NA,NA,p.Phe12Met,-1.03,-0.99,1,F342M +urn:mavedb:00000044-b-2#460,NA,NA,p.Phe12Met,-0.94,-0.99,2,F342M +urn:mavedb:00000044-b-2#463,NA,NA,p.Phe12Pro,-2.47,-2.47,1,F342P +urn:mavedb:00000044-b-2#464,NA,NA,p.Phe12Pro,-2.47,-2.47,2,F342P +urn:mavedb:00000044-b-2#469,NA,NA,p.Phe12Ser,-2.47,-2.41,1,F342S +urn:mavedb:00000044-b-2#470,NA,NA,p.Phe12Ser,-2.35,-2.41,2,F342S +urn:mavedb:00000044-b-2#471,NA,NA,p.Phe12Thr,-2.35,-2.28,1,F342T +urn:mavedb:00000044-b-2#472,NA,NA,p.Phe12Thr,-2.21,-2.28,2,F342T +urn:mavedb:00000044-b-2#475,NA,NA,p.Phe12Trp,-2.41,-2.3,1,F342W +urn:mavedb:00000044-b-2#476,NA,NA,p.Phe12Trp,-2.19,-2.3,2,F342W +urn:mavedb:00000044-b-2#477,NA,NA,p.Phe12Tyr,-2.23,-2.21,1,F342Y +urn:mavedb:00000044-b-2#478,NA,NA,p.Phe12Tyr,-2.18,-2.21,2,F342Y +urn:mavedb:00000044-b-2#473,NA,NA,p.Phe12Val,-1.32,-1.23,1,F342V +urn:mavedb:00000044-b-2#474,NA,NA,p.Phe12Val,-1.15,-1.23,2,F342V +urn:mavedb:00000044-b-2#5359,NA,NA,p.Phe134*,-4.58,-4.58,1,F464 +urn:mavedb:00000044-b-2#5360,NA,NA,p.Phe134*,-4.57,-4.58,2,F464 +urn:mavedb:00000044-b-2#5321,NA,NA,p.Phe134Ala,-1.06,-0.94,1,F464A +urn:mavedb:00000044-b-2#5322,NA,NA,p.Phe134Ala,-0.81,-0.94,2,F464A +urn:mavedb:00000044-b-2#5347,NA,NA,p.Phe134Arg,-1.25,-1.21,1,F464R +urn:mavedb:00000044-b-2#5348,NA,NA,p.Phe134Arg,-1.17,-1.21,2,F464R +urn:mavedb:00000044-b-2#5341,NA,NA,p.Phe134Asn,-0.47,-0.65,1,F464N +urn:mavedb:00000044-b-2#5342,NA,NA,p.Phe134Asn,-0.83,-0.65,2,F464N +urn:mavedb:00000044-b-2#5325,NA,NA,p.Phe134Asp,-1.45,-1.44,1,F464D +urn:mavedb:00000044-b-2#5326,NA,NA,p.Phe134Asp,-1.44,-1.44,2,F464D +urn:mavedb:00000044-b-2#5323,NA,NA,p.Phe134Cys,-1.23,-1.35,1,F464C +urn:mavedb:00000044-b-2#5324,NA,NA,p.Phe134Cys,-1.47,-1.35,2,F464C +urn:mavedb:00000044-b-2#5345,NA,NA,p.Phe134Gln,-0.87,-0.85,1,F464Q +urn:mavedb:00000044-b-2#5346,NA,NA,p.Phe134Gln,-0.83,-0.85,2,F464Q +urn:mavedb:00000044-b-2#5327,NA,NA,p.Phe134Glu,-1.39,-1.13,1,F464E +urn:mavedb:00000044-b-2#5328,NA,NA,p.Phe134Glu,-0.88,-1.13,2,F464E +urn:mavedb:00000044-b-2#5329,NA,NA,p.Phe134Gly,-0.02,-0.02,1,F464G +urn:mavedb:00000044-b-2#5330,NA,NA,p.Phe134Gly,-0.02,-0.02,2,F464G +urn:mavedb:00000044-b-2#5331,NA,NA,p.Phe134His,-0.38,-0.44,1,F464H +urn:mavedb:00000044-b-2#5332,NA,NA,p.Phe134His,-0.51,-0.44,2,F464H +urn:mavedb:00000044-b-2#5333,NA,NA,p.Phe134Ile,-1.88,-1.91,1,F464I +urn:mavedb:00000044-b-2#5334,NA,NA,p.Phe134Ile,-1.95,-1.91,2,F464I +urn:mavedb:00000044-b-2#5337,NA,NA,p.Phe134Leu,-0.57,-0.72,1,F464L +urn:mavedb:00000044-b-2#5338,NA,NA,p.Phe134Leu,-0.87,-0.72,2,F464L +urn:mavedb:00000044-b-2#5335,NA,NA,p.Phe134Lys,-1.66,-1.71,1,F464K +urn:mavedb:00000044-b-2#5336,NA,NA,p.Phe134Lys,-1.76,-1.71,2,F464K +urn:mavedb:00000044-b-2#5339,NA,NA,p.Phe134Met,-0.64,-0.52,1,F464M +urn:mavedb:00000044-b-2#5340,NA,NA,p.Phe134Met,-0.41,-0.52,2,F464M +urn:mavedb:00000044-b-2#5343,NA,NA,p.Phe134Pro,-2.63,-2.4,1,F464P +urn:mavedb:00000044-b-2#5344,NA,NA,p.Phe134Pro,-2.16,-2.4,2,F464P +urn:mavedb:00000044-b-2#5349,NA,NA,p.Phe134Ser,-0.75,-0.75,1,F464S +urn:mavedb:00000044-b-2#5350,NA,NA,p.Phe134Ser,-0.74,-0.75,2,F464S +urn:mavedb:00000044-b-2#5351,NA,NA,p.Phe134Thr,-1.11,-1.32,1,F464T +urn:mavedb:00000044-b-2#5352,NA,NA,p.Phe134Thr,-1.53,-1.32,2,F464T +urn:mavedb:00000044-b-2#5355,NA,NA,p.Phe134Trp,-0.39,-0.34,1,F464W +urn:mavedb:00000044-b-2#5356,NA,NA,p.Phe134Trp,-0.29,-0.34,2,F464W +urn:mavedb:00000044-b-2#5357,NA,NA,p.Phe134Tyr,0.21,0.19,1,F464Y +urn:mavedb:00000044-b-2#5358,NA,NA,p.Phe134Tyr,0.17,0.19,2,F464Y +urn:mavedb:00000044-b-2#5353,NA,NA,p.Phe134Val,-2.19,-1.91,1,F464V +urn:mavedb:00000044-b-2#5354,NA,NA,p.Phe134Val,-1.64,-1.91,2,F464V +urn:mavedb:00000044-b-2#6239,NA,NA,p.Phe156*,-4.58,-4.55,1,F486 +urn:mavedb:00000044-b-2#6240,NA,NA,p.Phe156*,-4.51,-4.55,2,F486 +urn:mavedb:00000044-b-2#6201,NA,NA,p.Phe156Ala,0.06,0.1,1,F486A +urn:mavedb:00000044-b-2#6202,NA,NA,p.Phe156Ala,0.15,0.1,2,F486A +urn:mavedb:00000044-b-2#6227,NA,NA,p.Phe156Arg,0.1,0.15,1,F486R +urn:mavedb:00000044-b-2#6228,NA,NA,p.Phe156Arg,0.21,0.15,2,F486R +urn:mavedb:00000044-b-2#6221,NA,NA,p.Phe156Asn,-0.01,0.04,1,F486N +urn:mavedb:00000044-b-2#6222,NA,NA,p.Phe156Asn,0.09,0.04,2,F486N +urn:mavedb:00000044-b-2#6205,NA,NA,p.Phe156Asp,0.12,0.11,1,F486D +urn:mavedb:00000044-b-2#6206,NA,NA,p.Phe156Asp,0.1,0.11,2,F486D +urn:mavedb:00000044-b-2#6203,NA,NA,p.Phe156Cys,-0.07,-0.07,1,F486C +urn:mavedb:00000044-b-2#6204,NA,NA,p.Phe156Cys,-0.07,-0.07,2,F486C +urn:mavedb:00000044-b-2#6225,NA,NA,p.Phe156Gln,0.32,0.22,1,F486Q +urn:mavedb:00000044-b-2#6226,NA,NA,p.Phe156Gln,0.11,0.22,2,F486Q +urn:mavedb:00000044-b-2#6207,NA,NA,p.Phe156Glu,0.42,0.28,1,F486E +urn:mavedb:00000044-b-2#6208,NA,NA,p.Phe156Glu,0.15,0.28,2,F486E +urn:mavedb:00000044-b-2#6209,NA,NA,p.Phe156Gly,0.07,-0.08,1,F486G +urn:mavedb:00000044-b-2#6210,NA,NA,p.Phe156Gly,-0.23,-0.08,2,F486G +urn:mavedb:00000044-b-2#6211,NA,NA,p.Phe156His,-0.04,0.05,1,F486H +urn:mavedb:00000044-b-2#6212,NA,NA,p.Phe156His,0.15,0.05,2,F486H +urn:mavedb:00000044-b-2#6213,NA,NA,p.Phe156Ile,-0.01,0.04,1,F486I +urn:mavedb:00000044-b-2#6214,NA,NA,p.Phe156Ile,0.09,0.04,2,F486I +urn:mavedb:00000044-b-2#6217,NA,NA,p.Phe156Leu,0.06,0.03,1,F486L +urn:mavedb:00000044-b-2#6218,NA,NA,p.Phe156Leu,0.01,0.03,2,F486L +urn:mavedb:00000044-b-2#6215,NA,NA,p.Phe156Lys,0.19,0.18,1,F486K +urn:mavedb:00000044-b-2#6216,NA,NA,p.Phe156Lys,0.17,0.18,2,F486K +urn:mavedb:00000044-b-2#6219,NA,NA,p.Phe156Met,-0.02,0.04,1,F486M +urn:mavedb:00000044-b-2#6220,NA,NA,p.Phe156Met,0.09,0.04,2,F486M +urn:mavedb:00000044-b-2#6223,NA,NA,p.Phe156Pro,0.12,0.22,1,F486P +urn:mavedb:00000044-b-2#6224,NA,NA,p.Phe156Pro,0.33,0.22,2,F486P +urn:mavedb:00000044-b-2#6229,NA,NA,p.Phe156Ser,0.1,0.13,1,F486S +urn:mavedb:00000044-b-2#6230,NA,NA,p.Phe156Ser,0.17,0.13,2,F486S +urn:mavedb:00000044-b-2#6231,NA,NA,p.Phe156Thr,0.13,0.13,1,F486T +urn:mavedb:00000044-b-2#6232,NA,NA,p.Phe156Thr,0.12,0.13,2,F486T +urn:mavedb:00000044-b-2#6235,NA,NA,p.Phe156Trp,0.02,-0.12,1,F486W +urn:mavedb:00000044-b-2#6236,NA,NA,p.Phe156Trp,-0.25,-0.12,2,F486W +urn:mavedb:00000044-b-2#6237,NA,NA,p.Phe156Tyr,0.05,0.04,1,F486Y +urn:mavedb:00000044-b-2#6238,NA,NA,p.Phe156Tyr,0.03,0.04,2,F486Y +urn:mavedb:00000044-b-2#6233,NA,NA,p.Phe156Val,0.03,0.07,1,F486V +urn:mavedb:00000044-b-2#6234,NA,NA,p.Phe156Val,0.11,0.07,2,F486V +urn:mavedb:00000044-b-2#6399,NA,NA,p.Phe160*,-4.43,-4.44,1,F490 +urn:mavedb:00000044-b-2#6400,NA,NA,p.Phe160*,-4.45,-4.44,2,F490 +urn:mavedb:00000044-b-2#6361,NA,NA,p.Phe160Ala,0.03,0.03,1,F490A +urn:mavedb:00000044-b-2#6362,NA,NA,p.Phe160Ala,0.03,0.03,2,F490A +urn:mavedb:00000044-b-2#6387,NA,NA,p.Phe160Arg,-0.01,-0.05,1,F490R +urn:mavedb:00000044-b-2#6388,NA,NA,p.Phe160Arg,-0.1,-0.05,2,F490R +urn:mavedb:00000044-b-2#6381,NA,NA,p.Phe160Asn,-0.01,0.03,1,F490N +urn:mavedb:00000044-b-2#6382,NA,NA,p.Phe160Asn,0.07,0.03,2,F490N +urn:mavedb:00000044-b-2#6365,NA,NA,p.Phe160Asp,-0.23,-0.33,1,F490D +urn:mavedb:00000044-b-2#6366,NA,NA,p.Phe160Asp,-0.42,-0.33,2,F490D +urn:mavedb:00000044-b-2#6363,NA,NA,p.Phe160Cys,-0.37,-0.4,1,F490C +urn:mavedb:00000044-b-2#6364,NA,NA,p.Phe160Cys,-0.44,-0.4,2,F490C +urn:mavedb:00000044-b-2#6385,NA,NA,p.Phe160Gln,-0.01,0.02,1,F490Q +urn:mavedb:00000044-b-2#6386,NA,NA,p.Phe160Gln,0.06,0.02,2,F490Q +urn:mavedb:00000044-b-2#6367,NA,NA,p.Phe160Glu,-0.09,-0.18,1,F490E +urn:mavedb:00000044-b-2#6368,NA,NA,p.Phe160Glu,-0.26,-0.18,2,F490E +urn:mavedb:00000044-b-2#6369,NA,NA,p.Phe160Gly,-0.56,-0.46,1,F490G +urn:mavedb:00000044-b-2#6370,NA,NA,p.Phe160Gly,-0.36,-0.46,2,F490G +urn:mavedb:00000044-b-2#6371,NA,NA,p.Phe160His,-0.01,-0.04,1,F490H +urn:mavedb:00000044-b-2#6372,NA,NA,p.Phe160His,-0.07,-0.04,2,F490H +urn:mavedb:00000044-b-2#6373,NA,NA,p.Phe160Ile,-0.51,-0.47,1,F490I +urn:mavedb:00000044-b-2#6374,NA,NA,p.Phe160Ile,-0.44,-0.47,2,F490I +urn:mavedb:00000044-b-2#6377,NA,NA,p.Phe160Leu,-0.38,-0.35,1,F490L +urn:mavedb:00000044-b-2#6378,NA,NA,p.Phe160Leu,-0.32,-0.35,2,F490L +urn:mavedb:00000044-b-2#6375,NA,NA,p.Phe160Lys,0.03,-0.07,1,F490K +urn:mavedb:00000044-b-2#6376,NA,NA,p.Phe160Lys,-0.18,-0.07,2,F490K +urn:mavedb:00000044-b-2#6379,NA,NA,p.Phe160Met,-0.19,-0.2,1,F490M +urn:mavedb:00000044-b-2#6380,NA,NA,p.Phe160Met,-0.21,-0.2,2,F490M +urn:mavedb:00000044-b-2#6383,NA,NA,p.Phe160Pro,-0.14,-0.13,1,F490P +urn:mavedb:00000044-b-2#6384,NA,NA,p.Phe160Pro,-0.12,-0.13,2,F490P +urn:mavedb:00000044-b-2#6389,NA,NA,p.Phe160Ser,-0.07,-0.1,1,F490S +urn:mavedb:00000044-b-2#6390,NA,NA,p.Phe160Ser,-0.12,-0.1,2,F490S +urn:mavedb:00000044-b-2#6391,NA,NA,p.Phe160Thr,-0.25,-0.25,1,F490T +urn:mavedb:00000044-b-2#6392,NA,NA,p.Phe160Thr,-0.26,-0.25,2,F490T +urn:mavedb:00000044-b-2#6395,NA,NA,p.Phe160Trp,-0.17,-0.03,1,F490W +urn:mavedb:00000044-b-2#6396,NA,NA,p.Phe160Trp,0.1,-0.03,2,F490W +urn:mavedb:00000044-b-2#6397,NA,NA,p.Phe160Tyr,0.2,0.1,1,F490Y +urn:mavedb:00000044-b-2#6398,NA,NA,p.Phe160Tyr,0.01,0.1,2,F490Y +urn:mavedb:00000044-b-2#6393,NA,NA,p.Phe160Val,-0.44,-0.36,1,F490V +urn:mavedb:00000044-b-2#6394,NA,NA,p.Phe160Val,-0.28,-0.36,2,F490V +urn:mavedb:00000044-b-2#6679,NA,NA,p.Phe167*,-4.68,-4.61,1,F497 +urn:mavedb:00000044-b-2#6680,NA,NA,p.Phe167*,-4.54,-4.61,2,F497 +urn:mavedb:00000044-b-2#6641,NA,NA,p.Phe167Ala,-1.92,-1.95,1,F497A +urn:mavedb:00000044-b-2#6642,NA,NA,p.Phe167Ala,-1.98,-1.95,2,F497A +urn:mavedb:00000044-b-2#6667,NA,NA,p.Phe167Arg,-2.34,-2.31,1,F497R +urn:mavedb:00000044-b-2#6668,NA,NA,p.Phe167Arg,-2.29,-2.31,2,F497R +urn:mavedb:00000044-b-2#6661,NA,NA,p.Phe167Asn,-2.13,-2.04,1,F497N +urn:mavedb:00000044-b-2#6662,NA,NA,p.Phe167Asn,-1.95,-2.04,2,F497N +urn:mavedb:00000044-b-2#6645,NA,NA,p.Phe167Asp,-2.19,-2.21,1,F497D +urn:mavedb:00000044-b-2#6646,NA,NA,p.Phe167Asp,-2.24,-2.21,2,F497D +urn:mavedb:00000044-b-2#6643,NA,NA,p.Phe167Cys,-2.32,-2.35,1,F497C +urn:mavedb:00000044-b-2#6644,NA,NA,p.Phe167Cys,-2.37,-2.35,2,F497C +urn:mavedb:00000044-b-2#6665,NA,NA,p.Phe167Gln,-2.35,-2.06,1,F497Q +urn:mavedb:00000044-b-2#6666,NA,NA,p.Phe167Gln,-1.78,-2.06,2,F497Q +urn:mavedb:00000044-b-2#6647,NA,NA,p.Phe167Glu,-2.2,-2.15,1,F497E +urn:mavedb:00000044-b-2#6648,NA,NA,p.Phe167Glu,-2.1,-2.15,2,F497E +urn:mavedb:00000044-b-2#6649,NA,NA,p.Phe167Gly,-2.22,-2.14,1,F497G +urn:mavedb:00000044-b-2#6650,NA,NA,p.Phe167Gly,-2.06,-2.14,2,F497G +urn:mavedb:00000044-b-2#6651,NA,NA,p.Phe167His,-2.35,-2.17,1,F497H +urn:mavedb:00000044-b-2#6652,NA,NA,p.Phe167His,-2,-2.17,2,F497H +urn:mavedb:00000044-b-2#6653,NA,NA,p.Phe167Ile,-2.19,-2.22,1,F497I +urn:mavedb:00000044-b-2#6654,NA,NA,p.Phe167Ile,-2.25,-2.22,2,F497I +urn:mavedb:00000044-b-2#6657,NA,NA,p.Phe167Leu,-2.16,-2.06,1,F497L +urn:mavedb:00000044-b-2#6658,NA,NA,p.Phe167Leu,-1.97,-2.06,2,F497L +urn:mavedb:00000044-b-2#6655,NA,NA,p.Phe167Lys,-2.12,-2.01,1,F497K +urn:mavedb:00000044-b-2#6656,NA,NA,p.Phe167Lys,-1.9,-2.01,2,F497K +urn:mavedb:00000044-b-2#6659,NA,NA,p.Phe167Met,-2.05,-2.17,1,F497M +urn:mavedb:00000044-b-2#6660,NA,NA,p.Phe167Met,-2.28,-2.17,2,F497M +urn:mavedb:00000044-b-2#6663,NA,NA,p.Phe167Pro,-2.07,-2.04,1,F497P +urn:mavedb:00000044-b-2#6664,NA,NA,p.Phe167Pro,-2.01,-2.04,2,F497P +urn:mavedb:00000044-b-2#6669,NA,NA,p.Phe167Ser,-1.98,-2.05,1,F497S +urn:mavedb:00000044-b-2#6670,NA,NA,p.Phe167Ser,-2.12,-2.05,2,F497S +urn:mavedb:00000044-b-2#6671,NA,NA,p.Phe167Thr,-1.94,-1.91,1,F497T +urn:mavedb:00000044-b-2#6672,NA,NA,p.Phe167Thr,-1.88,-1.91,2,F497T +urn:mavedb:00000044-b-2#6675,NA,NA,p.Phe167Trp,-1.25,-1.43,1,F497W +urn:mavedb:00000044-b-2#6676,NA,NA,p.Phe167Trp,-1.61,-1.43,2,F497W +urn:mavedb:00000044-b-2#6677,NA,NA,p.Phe167Tyr,-1.86,-1.76,1,F497Y +urn:mavedb:00000044-b-2#6678,NA,NA,p.Phe167Tyr,-1.67,-1.76,2,F497Y +urn:mavedb:00000044-b-2#6673,NA,NA,p.Phe167Val,-2.17,-2.15,1,F497V +urn:mavedb:00000044-b-2#6674,NA,NA,p.Phe167Val,-2.13,-2.15,2,F497V +urn:mavedb:00000044-b-2#679,NA,NA,p.Phe17*,-4.65,-4.59,1,F347 +urn:mavedb:00000044-b-2#680,NA,NA,p.Phe17*,-4.54,-4.59,2,F347 +urn:mavedb:00000044-b-2#641,NA,NA,p.Phe17Ala,-2.21,-2.11,1,F347A +urn:mavedb:00000044-b-2#642,NA,NA,p.Phe17Ala,-2,-2.11,2,F347A +urn:mavedb:00000044-b-2#667,NA,NA,p.Phe17Arg,-2.58,-2.47,1,F347R +urn:mavedb:00000044-b-2#668,NA,NA,p.Phe17Arg,-2.37,-2.47,2,F347R +urn:mavedb:00000044-b-2#661,NA,NA,p.Phe17Asn,-1.56,-0.6,1,F347N +urn:mavedb:00000044-b-2#662,NA,NA,p.Phe17Asn,0.37,-0.6,2,F347N +urn:mavedb:00000044-b-2#645,NA,NA,p.Phe17Asp,-2.32,-1.66,1,F347D +urn:mavedb:00000044-b-2#646,NA,NA,p.Phe17Asp,-1,-1.66,2,F347D +urn:mavedb:00000044-b-2#643,NA,NA,p.Phe17Cys,-2.87,-2.62,1,F347C +urn:mavedb:00000044-b-2#644,NA,NA,p.Phe17Cys,-2.37,-2.62,2,F347C +urn:mavedb:00000044-b-2#665,NA,NA,p.Phe17Gln,-2.74,-2.51,1,F347Q +urn:mavedb:00000044-b-2#666,NA,NA,p.Phe17Gln,-2.28,-2.51,2,F347Q +urn:mavedb:00000044-b-2#647,NA,NA,p.Phe17Glu,-2.27,-2.35,1,F347E +urn:mavedb:00000044-b-2#648,NA,NA,p.Phe17Glu,-2.42,-2.35,2,F347E +urn:mavedb:00000044-b-2#649,NA,NA,p.Phe17Gly,-2.04,-1.93,1,F347G +urn:mavedb:00000044-b-2#650,NA,NA,p.Phe17Gly,-1.82,-1.93,2,F347G +urn:mavedb:00000044-b-2#651,NA,NA,p.Phe17His,-2.11,-0.87,1,F347H +urn:mavedb:00000044-b-2#652,NA,NA,p.Phe17His,0.37,-0.87,2,F347H +urn:mavedb:00000044-b-2#653,NA,NA,p.Phe17Ile,-1.96,-2.15,1,F347I +urn:mavedb:00000044-b-2#654,NA,NA,p.Phe17Ile,-2.33,-2.15,2,F347I +urn:mavedb:00000044-b-2#657,NA,NA,p.Phe17Leu,-2.31,-2.24,1,F347L +urn:mavedb:00000044-b-2#658,NA,NA,p.Phe17Leu,-2.18,-2.24,2,F347L +urn:mavedb:00000044-b-2#655,NA,NA,p.Phe17Lys,-2.34,-2.15,1,F347K +urn:mavedb:00000044-b-2#656,NA,NA,p.Phe17Lys,-1.96,-2.15,2,F347K +urn:mavedb:00000044-b-2#659,NA,NA,p.Phe17Met,-1.49,-1.48,1,F347M +urn:mavedb:00000044-b-2#660,NA,NA,p.Phe17Met,-1.46,-1.48,2,F347M +urn:mavedb:00000044-b-2#663,NA,NA,p.Phe17Pro,-2,-1.97,1,F347P +urn:mavedb:00000044-b-2#664,NA,NA,p.Phe17Pro,-1.95,-1.97,2,F347P +urn:mavedb:00000044-b-2#669,NA,NA,p.Phe17Ser,-2.1,-2.11,1,F347S +urn:mavedb:00000044-b-2#670,NA,NA,p.Phe17Ser,-2.12,-2.11,2,F347S +urn:mavedb:00000044-b-2#671,NA,NA,p.Phe17Thr,-2.39,-2.29,1,F347T +urn:mavedb:00000044-b-2#672,NA,NA,p.Phe17Thr,-2.18,-2.29,2,F347T +urn:mavedb:00000044-b-2#675,NA,NA,p.Phe17Trp,-0.09,0.06,1,F347W +urn:mavedb:00000044-b-2#676,NA,NA,p.Phe17Trp,0.2,0.06,2,F347W +urn:mavedb:00000044-b-2#677,NA,NA,p.Phe17Tyr,-1.44,-1.39,1,F347Y +urn:mavedb:00000044-b-2#678,NA,NA,p.Phe17Tyr,-1.34,-1.39,2,F347Y +urn:mavedb:00000044-b-2#673,NA,NA,p.Phe17Val,-1.8,-1.99,1,F347V +urn:mavedb:00000044-b-2#674,NA,NA,p.Phe17Val,-2.18,-1.99,2,F347V +urn:mavedb:00000044-b-2#7399,NA,NA,p.Phe185*,-3.65,-3.74,1,F515 +urn:mavedb:00000044-b-2#7400,NA,NA,p.Phe185*,-3.82,-3.74,2,F515 +urn:mavedb:00000044-b-2#7361,NA,NA,p.Phe185Ala,-2.92,-2.51,1,F515A +urn:mavedb:00000044-b-2#7362,NA,NA,p.Phe185Ala,-2.09,-2.51,2,F515A +urn:mavedb:00000044-b-2#7387,NA,NA,p.Phe185Arg,-2.99,-2.91,1,F515R +urn:mavedb:00000044-b-2#7388,NA,NA,p.Phe185Arg,-2.84,-2.91,2,F515R +urn:mavedb:00000044-b-2#7381,NA,NA,p.Phe185Asn,-2.92,-2.63,1,F515N +urn:mavedb:00000044-b-2#7382,NA,NA,p.Phe185Asn,-2.34,-2.63,2,F515N +urn:mavedb:00000044-b-2#7365,NA,NA,p.Phe185Asp,-2.79,-2.77,1,F515D +urn:mavedb:00000044-b-2#7366,NA,NA,p.Phe185Asp,-2.75,-2.77,2,F515D +urn:mavedb:00000044-b-2#7363,NA,NA,p.Phe185Cys,-1.99,-1.94,1,F515C +urn:mavedb:00000044-b-2#7364,NA,NA,p.Phe185Cys,-1.9,-1.94,2,F515C +urn:mavedb:00000044-b-2#7385,NA,NA,p.Phe185Gln,-3.19,-3.1,1,F515Q +urn:mavedb:00000044-b-2#7386,NA,NA,p.Phe185Gln,-3.01,-3.1,2,F515Q +urn:mavedb:00000044-b-2#7367,NA,NA,p.Phe185Glu,-2.9,-2.87,1,F515E +urn:mavedb:00000044-b-2#7368,NA,NA,p.Phe185Glu,-2.85,-2.87,2,F515E +urn:mavedb:00000044-b-2#7369,NA,NA,p.Phe185Gly,-1.86,-1.92,1,F515G +urn:mavedb:00000044-b-2#7370,NA,NA,p.Phe185Gly,-1.98,-1.92,2,F515G +urn:mavedb:00000044-b-2#7371,NA,NA,p.Phe185His,-2.28,-2.61,1,F515H +urn:mavedb:00000044-b-2#7372,NA,NA,p.Phe185His,-2.94,-2.61,2,F515H +urn:mavedb:00000044-b-2#7373,NA,NA,p.Phe185Ile,-1.26,-1.21,1,F515I +urn:mavedb:00000044-b-2#7374,NA,NA,p.Phe185Ile,-1.16,-1.21,2,F515I +urn:mavedb:00000044-b-2#7377,NA,NA,p.Phe185Leu,-0.76,-0.74,1,F515L +urn:mavedb:00000044-b-2#7378,NA,NA,p.Phe185Leu,-0.72,-0.74,2,F515L +urn:mavedb:00000044-b-2#7375,NA,NA,p.Phe185Lys,-3.07,-3.07,1,F515K +urn:mavedb:00000044-b-2#7376,NA,NA,p.Phe185Lys,-3.08,-3.07,2,F515K +urn:mavedb:00000044-b-2#7379,NA,NA,p.Phe185Met,-0.44,-0.38,1,F515M +urn:mavedb:00000044-b-2#7380,NA,NA,p.Phe185Met,-0.33,-0.38,2,F515M +urn:mavedb:00000044-b-2#7383,NA,NA,p.Phe185Pro,-2.56,-2.48,1,F515P +urn:mavedb:00000044-b-2#7384,NA,NA,p.Phe185Pro,-2.39,-2.48,2,F515P +urn:mavedb:00000044-b-2#7389,NA,NA,p.Phe185Ser,-2.79,-2.85,1,F515S +urn:mavedb:00000044-b-2#7390,NA,NA,p.Phe185Ser,-2.9,-2.85,2,F515S +urn:mavedb:00000044-b-2#7391,NA,NA,p.Phe185Thr,-2.9,-2.85,1,F515T +urn:mavedb:00000044-b-2#7392,NA,NA,p.Phe185Thr,-2.81,-2.85,2,F515T +urn:mavedb:00000044-b-2#7395,NA,NA,p.Phe185Trp,-1.45,-1.42,1,F515W +urn:mavedb:00000044-b-2#7396,NA,NA,p.Phe185Trp,-1.39,-1.42,2,F515W +urn:mavedb:00000044-b-2#7397,NA,NA,p.Phe185Tyr,-0.92,-1.02,1,F515Y +urn:mavedb:00000044-b-2#7398,NA,NA,p.Phe185Tyr,-1.12,-1.02,2,F515Y +urn:mavedb:00000044-b-2#7393,NA,NA,p.Phe185Val,-1.76,-1.71,1,F515V +urn:mavedb:00000044-b-2#7394,NA,NA,p.Phe185Val,-1.67,-1.71,2,F515V +urn:mavedb:00000044-b-2#1759,NA,NA,p.Phe44*,-4.65,-4.6,1,F374 +urn:mavedb:00000044-b-2#1760,NA,NA,p.Phe44*,-4.55,-4.6,2,F374 +urn:mavedb:00000044-b-2#1721,NA,NA,p.Phe44Ala,-0.97,-0.98,1,F374A +urn:mavedb:00000044-b-2#1722,NA,NA,p.Phe44Ala,-0.99,-0.98,2,F374A +urn:mavedb:00000044-b-2#1747,NA,NA,p.Phe44Arg,-1.43,-1.36,1,F374R +urn:mavedb:00000044-b-2#1748,NA,NA,p.Phe44Arg,-1.28,-1.36,2,F374R +urn:mavedb:00000044-b-2#1741,NA,NA,p.Phe44Asn,-0.36,-0.32,1,F374N +urn:mavedb:00000044-b-2#1742,NA,NA,p.Phe44Asn,-0.28,-0.32,2,F374N +urn:mavedb:00000044-b-2#1725,NA,NA,p.Phe44Asp,-0.5,-0.55,1,F374D +urn:mavedb:00000044-b-2#1726,NA,NA,p.Phe44Asp,-0.6,-0.55,2,F374D +urn:mavedb:00000044-b-2#1723,NA,NA,p.Phe44Cys,-1.52,-1.43,1,F374C +urn:mavedb:00000044-b-2#1724,NA,NA,p.Phe44Cys,-1.34,-1.43,2,F374C +urn:mavedb:00000044-b-2#1745,NA,NA,p.Phe44Gln,-1,-0.87,1,F374Q +urn:mavedb:00000044-b-2#1746,NA,NA,p.Phe44Gln,-0.75,-0.87,2,F374Q +urn:mavedb:00000044-b-2#1727,NA,NA,p.Phe44Glu,-1.13,-1.24,1,F374E +urn:mavedb:00000044-b-2#1728,NA,NA,p.Phe44Glu,-1.35,-1.24,2,F374E +urn:mavedb:00000044-b-2#1729,NA,NA,p.Phe44Gly,-1.24,-1.13,1,F374G +urn:mavedb:00000044-b-2#1730,NA,NA,p.Phe44Gly,-1.01,-1.13,2,F374G +urn:mavedb:00000044-b-2#1731,NA,NA,p.Phe44His,-0.47,-0.6,1,F374H +urn:mavedb:00000044-b-2#1732,NA,NA,p.Phe44His,-0.72,-0.6,2,F374H +urn:mavedb:00000044-b-2#1733,NA,NA,p.Phe44Ile,-0.49,-0.48,1,F374I +urn:mavedb:00000044-b-2#1734,NA,NA,p.Phe44Ile,-0.48,-0.48,2,F374I +urn:mavedb:00000044-b-2#1737,NA,NA,p.Phe44Leu,-0.82,-0.77,1,F374L +urn:mavedb:00000044-b-2#1738,NA,NA,p.Phe44Leu,-0.73,-0.77,2,F374L +urn:mavedb:00000044-b-2#1735,NA,NA,p.Phe44Lys,-1.41,-1.24,1,F374K +urn:mavedb:00000044-b-2#1736,NA,NA,p.Phe44Lys,-1.07,-1.24,2,F374K +urn:mavedb:00000044-b-2#1739,NA,NA,p.Phe44Met,-0.91,-0.89,1,F374M +urn:mavedb:00000044-b-2#1740,NA,NA,p.Phe44Met,-0.87,-0.89,2,F374M +urn:mavedb:00000044-b-2#1743,NA,NA,p.Phe44Pro,-1.06,-1.14,1,F374P +urn:mavedb:00000044-b-2#1744,NA,NA,p.Phe44Pro,-1.22,-1.14,2,F374P +urn:mavedb:00000044-b-2#1749,NA,NA,p.Phe44Ser,-0.97,-1.1,1,F374S +urn:mavedb:00000044-b-2#1750,NA,NA,p.Phe44Ser,-1.23,-1.1,2,F374S +urn:mavedb:00000044-b-2#1751,NA,NA,p.Phe44Thr,-0.85,-0.87,1,F374T +urn:mavedb:00000044-b-2#1752,NA,NA,p.Phe44Thr,-0.9,-0.87,2,F374T +urn:mavedb:00000044-b-2#1755,NA,NA,p.Phe44Trp,0.08,0.06,1,F374W +urn:mavedb:00000044-b-2#1756,NA,NA,p.Phe44Trp,0.04,0.06,2,F374W +urn:mavedb:00000044-b-2#1757,NA,NA,p.Phe44Tyr,-0.13,-0.12,1,F374Y +urn:mavedb:00000044-b-2#1758,NA,NA,p.Phe44Tyr,-0.12,-0.12,2,F374Y +urn:mavedb:00000044-b-2#1753,NA,NA,p.Phe44Val,-0.84,-0.85,1,F374V +urn:mavedb:00000044-b-2#1754,NA,NA,p.Phe44Val,-0.87,-0.85,2,F374V +urn:mavedb:00000044-b-2#1879,NA,NA,p.Phe47*,-4.67,-4.61,1,F377 +urn:mavedb:00000044-b-2#1880,NA,NA,p.Phe47*,-4.56,-4.61,2,F377 +urn:mavedb:00000044-b-2#1841,NA,NA,p.Phe47Ala,-2.02,-2.17,1,F377A +urn:mavedb:00000044-b-2#1842,NA,NA,p.Phe47Ala,-2.31,-2.17,2,F377A +urn:mavedb:00000044-b-2#1867,NA,NA,p.Phe47Arg,-3.04,-2.92,1,F377R +urn:mavedb:00000044-b-2#1868,NA,NA,p.Phe47Arg,-2.79,-2.92,2,F377R +urn:mavedb:00000044-b-2#1861,NA,NA,p.Phe47Asn,-2.44,-2.42,1,F377N +urn:mavedb:00000044-b-2#1862,NA,NA,p.Phe47Asn,-2.4,-2.42,2,F377N +urn:mavedb:00000044-b-2#1845,NA,NA,p.Phe47Asp,-2.76,-2.75,1,F377D +urn:mavedb:00000044-b-2#1846,NA,NA,p.Phe47Asp,-2.75,-2.75,2,F377D +urn:mavedb:00000044-b-2#1843,NA,NA,p.Phe47Cys,-1.2,-1.24,1,F377C +urn:mavedb:00000044-b-2#1844,NA,NA,p.Phe47Cys,-1.28,-1.24,2,F377C +urn:mavedb:00000044-b-2#1865,NA,NA,p.Phe47Gln,-3.04,-2.96,1,F377Q +urn:mavedb:00000044-b-2#1866,NA,NA,p.Phe47Gln,-2.88,-2.96,2,F377Q +urn:mavedb:00000044-b-2#1847,NA,NA,p.Phe47Glu,-3.31,-3.19,1,F377E +urn:mavedb:00000044-b-2#1848,NA,NA,p.Phe47Glu,-3.06,-3.19,2,F377E +urn:mavedb:00000044-b-2#1849,NA,NA,p.Phe47Gly,-2.95,-2.93,1,F377G +urn:mavedb:00000044-b-2#1850,NA,NA,p.Phe47Gly,-2.9,-2.93,2,F377G +urn:mavedb:00000044-b-2#1851,NA,NA,p.Phe47His,-2.42,-2.62,1,F377H +urn:mavedb:00000044-b-2#1852,NA,NA,p.Phe47His,-2.82,-2.62,2,F377H +urn:mavedb:00000044-b-2#1853,NA,NA,p.Phe47Ile,-0.5,-0.57,1,F377I +urn:mavedb:00000044-b-2#1854,NA,NA,p.Phe47Ile,-0.65,-0.57,2,F377I +urn:mavedb:00000044-b-2#1857,NA,NA,p.Phe47Leu,-0.72,-0.8,1,F377L +urn:mavedb:00000044-b-2#1858,NA,NA,p.Phe47Leu,-0.89,-0.8,2,F377L +urn:mavedb:00000044-b-2#1855,NA,NA,p.Phe47Lys,-2.5,-2.42,1,F377K +urn:mavedb:00000044-b-2#1856,NA,NA,p.Phe47Lys,-2.34,-2.42,2,F377K +urn:mavedb:00000044-b-2#1859,NA,NA,p.Phe47Met,-0.39,-0.58,1,F377M +urn:mavedb:00000044-b-2#1860,NA,NA,p.Phe47Met,-0.76,-0.58,2,F377M +urn:mavedb:00000044-b-2#1863,NA,NA,p.Phe47Pro,-2.86,-2.18,1,F377P +urn:mavedb:00000044-b-2#1864,NA,NA,p.Phe47Pro,-1.5,-2.18,2,F377P +urn:mavedb:00000044-b-2#1869,NA,NA,p.Phe47Ser,-2.35,-2.28,1,F377S +urn:mavedb:00000044-b-2#1870,NA,NA,p.Phe47Ser,-2.21,-2.28,2,F377S +urn:mavedb:00000044-b-2#1871,NA,NA,p.Phe47Thr,-1.53,-1.61,1,F377T +urn:mavedb:00000044-b-2#1872,NA,NA,p.Phe47Thr,-1.7,-1.61,2,F377T +urn:mavedb:00000044-b-2#1875,NA,NA,p.Phe47Trp,-0.29,-0.5,1,F377W +urn:mavedb:00000044-b-2#1876,NA,NA,p.Phe47Trp,-0.72,-0.5,2,F377W +urn:mavedb:00000044-b-2#1877,NA,NA,p.Phe47Tyr,-1.45,-1.37,1,F377Y +urn:mavedb:00000044-b-2#1878,NA,NA,p.Phe47Tyr,-1.28,-1.37,2,F377Y +urn:mavedb:00000044-b-2#1873,NA,NA,p.Phe47Val,-0.35,-0.4,1,F377V +urn:mavedb:00000044-b-2#1874,NA,NA,p.Phe47Val,-0.45,-0.4,2,F377V +urn:mavedb:00000044-b-2#2479,NA,NA,p.Phe62*,-4.61,-4.58,1,F392 +urn:mavedb:00000044-b-2#2480,NA,NA,p.Phe62*,-4.55,-4.58,2,F392 +urn:mavedb:00000044-b-2#2441,NA,NA,p.Phe62Ala,0.12,0.02,1,F392A +urn:mavedb:00000044-b-2#2442,NA,NA,p.Phe62Ala,-0.07,0.02,2,F392A +urn:mavedb:00000044-b-2#2467,NA,NA,p.Phe62Arg,-1.45,-1.39,1,F392R +urn:mavedb:00000044-b-2#2468,NA,NA,p.Phe62Arg,-1.32,-1.39,2,F392R +urn:mavedb:00000044-b-2#2461,NA,NA,p.Phe62Asn,-0.94,-0.97,1,F392N +urn:mavedb:00000044-b-2#2462,NA,NA,p.Phe62Asn,-1,-0.97,2,F392N +urn:mavedb:00000044-b-2#2445,NA,NA,p.Phe62Asp,-1.65,-1.42,1,F392D +urn:mavedb:00000044-b-2#2446,NA,NA,p.Phe62Asp,-1.2,-1.42,2,F392D +urn:mavedb:00000044-b-2#2443,NA,NA,p.Phe62Cys,-0.09,-0.15,1,F392C +urn:mavedb:00000044-b-2#2444,NA,NA,p.Phe62Cys,-0.21,-0.15,2,F392C +urn:mavedb:00000044-b-2#2465,NA,NA,p.Phe62Gln,-1,-1.07,1,F392Q +urn:mavedb:00000044-b-2#2466,NA,NA,p.Phe62Gln,-1.14,-1.07,2,F392Q +urn:mavedb:00000044-b-2#2447,NA,NA,p.Phe62Glu,-1.48,-1.48,1,F392E +urn:mavedb:00000044-b-2#2448,NA,NA,p.Phe62Glu,-1.48,-1.48,2,F392E +urn:mavedb:00000044-b-2#2449,NA,NA,p.Phe62Gly,-1.03,-1.01,1,F392G +urn:mavedb:00000044-b-2#2450,NA,NA,p.Phe62Gly,-0.98,-1.01,2,F392G +urn:mavedb:00000044-b-2#2451,NA,NA,p.Phe62His,-0.86,-0.72,1,F392H +urn:mavedb:00000044-b-2#2452,NA,NA,p.Phe62His,-0.59,-0.72,2,F392H +urn:mavedb:00000044-b-2#2453,NA,NA,p.Phe62Ile,-0.07,-0.07,1,F392I +urn:mavedb:00000044-b-2#2454,NA,NA,p.Phe62Ile,-0.06,-0.07,2,F392I +urn:mavedb:00000044-b-2#2457,NA,NA,p.Phe62Leu,-0.3,-0.23,1,F392L +urn:mavedb:00000044-b-2#2458,NA,NA,p.Phe62Leu,-0.15,-0.23,2,F392L +urn:mavedb:00000044-b-2#2455,NA,NA,p.Phe62Lys,-1.54,-1.34,1,F392K +urn:mavedb:00000044-b-2#2456,NA,NA,p.Phe62Lys,-1.14,-1.34,2,F392K +urn:mavedb:00000044-b-2#2459,NA,NA,p.Phe62Met,-0.15,-0.12,1,F392M +urn:mavedb:00000044-b-2#2460,NA,NA,p.Phe62Met,-0.09,-0.12,2,F392M +urn:mavedb:00000044-b-2#2463,NA,NA,p.Phe62Pro,-0.22,-0.34,1,F392P +urn:mavedb:00000044-b-2#2464,NA,NA,p.Phe62Pro,-0.46,-0.34,2,F392P +urn:mavedb:00000044-b-2#2469,NA,NA,p.Phe62Ser,-0.5,-0.51,1,F392S +urn:mavedb:00000044-b-2#2470,NA,NA,p.Phe62Ser,-0.51,-0.51,2,F392S +urn:mavedb:00000044-b-2#2471,NA,NA,p.Phe62Thr,-0.18,-0.13,1,F392T +urn:mavedb:00000044-b-2#2472,NA,NA,p.Phe62Thr,-0.09,-0.13,2,F392T +urn:mavedb:00000044-b-2#2475,NA,NA,p.Phe62Trp,0.45,0.26,1,F392W +urn:mavedb:00000044-b-2#2476,NA,NA,p.Phe62Trp,0.06,0.26,2,F392W +urn:mavedb:00000044-b-2#2477,NA,NA,p.Phe62Tyr,-0.09,-0.04,1,F392Y +urn:mavedb:00000044-b-2#2478,NA,NA,p.Phe62Tyr,0,-0.04,2,F392Y +urn:mavedb:00000044-b-2#2473,NA,NA,p.Phe62Val,-0.04,0.01,1,F392V +urn:mavedb:00000044-b-2#2474,NA,NA,p.Phe62Val,0.06,0.01,2,F392V +urn:mavedb:00000044-b-2#2799,NA,NA,p.Phe70*,-4.65,-4.6,1,F400 +urn:mavedb:00000044-b-2#2800,NA,NA,p.Phe70*,-4.56,-4.6,2,F400 +urn:mavedb:00000044-b-2#2761,NA,NA,p.Phe70Ala,-2.92,-2.7,1,F400A +urn:mavedb:00000044-b-2#2762,NA,NA,p.Phe70Ala,-2.49,-2.7,2,F400A +urn:mavedb:00000044-b-2#2787,NA,NA,p.Phe70Arg,-2.96,-2.87,1,F400R +urn:mavedb:00000044-b-2#2788,NA,NA,p.Phe70Arg,-2.77,-2.87,2,F400R +urn:mavedb:00000044-b-2#2781,NA,NA,p.Phe70Asn,-2.79,-2.8,1,F400N +urn:mavedb:00000044-b-2#2782,NA,NA,p.Phe70Asn,-2.82,-2.8,2,F400N +urn:mavedb:00000044-b-2#2765,NA,NA,p.Phe70Asp,-2.6,-2.59,1,F400D +urn:mavedb:00000044-b-2#2766,NA,NA,p.Phe70Asp,-2.57,-2.59,2,F400D +urn:mavedb:00000044-b-2#2763,NA,NA,p.Phe70Cys,-2.88,-2.79,1,F400C +urn:mavedb:00000044-b-2#2764,NA,NA,p.Phe70Cys,-2.7,-2.79,2,F400C +urn:mavedb:00000044-b-2#2785,NA,NA,p.Phe70Gln,-2.87,-2.82,1,F400Q +urn:mavedb:00000044-b-2#2786,NA,NA,p.Phe70Gln,-2.77,-2.82,2,F400Q +urn:mavedb:00000044-b-2#2767,NA,NA,p.Phe70Glu,-2.8,-2.54,1,F400E +urn:mavedb:00000044-b-2#2768,NA,NA,p.Phe70Glu,-2.29,-2.54,2,F400E +urn:mavedb:00000044-b-2#2769,NA,NA,p.Phe70Gly,-2.69,-2.69,1,F400G +urn:mavedb:00000044-b-2#2770,NA,NA,p.Phe70Gly,-2.69,-2.69,2,F400G +urn:mavedb:00000044-b-2#2771,NA,NA,p.Phe70His,-2.91,-2.83,1,F400H +urn:mavedb:00000044-b-2#2772,NA,NA,p.Phe70His,-2.76,-2.83,2,F400H +urn:mavedb:00000044-b-2#2773,NA,NA,p.Phe70Ile,-2.77,-2.72,1,F400I +urn:mavedb:00000044-b-2#2774,NA,NA,p.Phe70Ile,-2.66,-2.72,2,F400I +urn:mavedb:00000044-b-2#2777,NA,NA,p.Phe70Leu,-2.78,-2.71,1,F400L +urn:mavedb:00000044-b-2#2778,NA,NA,p.Phe70Leu,-2.63,-2.71,2,F400L +urn:mavedb:00000044-b-2#2775,NA,NA,p.Phe70Lys,-2.75,-2.67,1,F400K +urn:mavedb:00000044-b-2#2776,NA,NA,p.Phe70Lys,-2.59,-2.67,2,F400K +urn:mavedb:00000044-b-2#2779,NA,NA,p.Phe70Met,-1.77,-1.72,1,F400M +urn:mavedb:00000044-b-2#2780,NA,NA,p.Phe70Met,-1.68,-1.72,2,F400M +urn:mavedb:00000044-b-2#2783,NA,NA,p.Phe70Pro,-2.7,-2.42,1,F400P +urn:mavedb:00000044-b-2#2784,NA,NA,p.Phe70Pro,-2.13,-2.42,2,F400P +urn:mavedb:00000044-b-2#2789,NA,NA,p.Phe70Ser,-2.86,-2.73,1,F400S +urn:mavedb:00000044-b-2#2790,NA,NA,p.Phe70Ser,-2.61,-2.73,2,F400S +urn:mavedb:00000044-b-2#2791,NA,NA,p.Phe70Thr,-2.91,-2.85,1,F400T +urn:mavedb:00000044-b-2#2792,NA,NA,p.Phe70Thr,-2.79,-2.85,2,F400T +urn:mavedb:00000044-b-2#2795,NA,NA,p.Phe70Trp,-2.91,-2.83,1,F400W +urn:mavedb:00000044-b-2#2796,NA,NA,p.Phe70Trp,-2.74,-2.83,2,F400W +urn:mavedb:00000044-b-2#2797,NA,NA,p.Phe70Tyr,-2.63,-2.5,1,F400Y +urn:mavedb:00000044-b-2#2798,NA,NA,p.Phe70Tyr,-2.38,-2.5,2,F400Y +urn:mavedb:00000044-b-2#2793,NA,NA,p.Phe70Val,-2.86,-2.81,1,F400V +urn:mavedb:00000044-b-2#2794,NA,NA,p.Phe70Val,-2.76,-2.81,2,F400V +urn:mavedb:00000044-b-2#319,NA,NA,p.Phe8*,-4.62,-4.6,1,F338 +urn:mavedb:00000044-b-2#320,NA,NA,p.Phe8*,-4.58,-4.6,2,F338 +urn:mavedb:00000044-b-2#281,NA,NA,p.Phe8Ala,-2.15,-2.18,1,F338A +urn:mavedb:00000044-b-2#282,NA,NA,p.Phe8Ala,-2.21,-2.18,2,F338A +urn:mavedb:00000044-b-2#307,NA,NA,p.Phe8Arg,-2.77,-2.6,1,F338R +urn:mavedb:00000044-b-2#308,NA,NA,p.Phe8Arg,-2.43,-2.6,2,F338R +urn:mavedb:00000044-b-2#301,NA,NA,p.Phe8Asn,-2.37,-2.3,1,F338N +urn:mavedb:00000044-b-2#302,NA,NA,p.Phe8Asn,-2.24,-2.3,2,F338N +urn:mavedb:00000044-b-2#285,NA,NA,p.Phe8Asp,-2.32,-2.24,1,F338D +urn:mavedb:00000044-b-2#286,NA,NA,p.Phe8Asp,-2.16,-2.24,2,F338D +urn:mavedb:00000044-b-2#283,NA,NA,p.Phe8Cys,-2.1,-2.08,1,F338C +urn:mavedb:00000044-b-2#284,NA,NA,p.Phe8Cys,-2.06,-2.08,2,F338C +urn:mavedb:00000044-b-2#305,NA,NA,p.Phe8Gln,-2.55,-2.37,1,F338Q +urn:mavedb:00000044-b-2#306,NA,NA,p.Phe8Gln,-2.2,-2.37,2,F338Q +urn:mavedb:00000044-b-2#287,NA,NA,p.Phe8Glu,-2.05,-2.13,1,F338E +urn:mavedb:00000044-b-2#288,NA,NA,p.Phe8Glu,-2.21,-2.13,2,F338E +urn:mavedb:00000044-b-2#289,NA,NA,p.Phe8Gly,-1.99,-2.11,1,F338G +urn:mavedb:00000044-b-2#290,NA,NA,p.Phe8Gly,-2.22,-2.11,2,F338G +urn:mavedb:00000044-b-2#291,NA,NA,p.Phe8His,-2.17,-1.88,1,F338H +urn:mavedb:00000044-b-2#292,NA,NA,p.Phe8His,-1.58,-1.88,2,F338H +urn:mavedb:00000044-b-2#293,NA,NA,p.Phe8Ile,-0.38,-0.48,1,F338I +urn:mavedb:00000044-b-2#294,NA,NA,p.Phe8Ile,-0.58,-0.48,2,F338I +urn:mavedb:00000044-b-2#297,NA,NA,p.Phe8Leu,0.08,0.06,1,F338L +urn:mavedb:00000044-b-2#298,NA,NA,p.Phe8Leu,0.04,0.06,2,F338L +urn:mavedb:00000044-b-2#295,NA,NA,p.Phe8Lys,-2.33,-2.31,1,F338K +urn:mavedb:00000044-b-2#296,NA,NA,p.Phe8Lys,-2.3,-2.31,2,F338K +urn:mavedb:00000044-b-2#299,NA,NA,p.Phe8Met,-0.41,-0.59,1,F338M +urn:mavedb:00000044-b-2#300,NA,NA,p.Phe8Met,-0.78,-0.59,2,F338M +urn:mavedb:00000044-b-2#303,NA,NA,p.Phe8Pro,-2.3,-2.24,1,F338P +urn:mavedb:00000044-b-2#304,NA,NA,p.Phe8Pro,-2.17,-2.24,2,F338P +urn:mavedb:00000044-b-2#309,NA,NA,p.Phe8Ser,-2.32,-2.31,1,F338S +urn:mavedb:00000044-b-2#310,NA,NA,p.Phe8Ser,-2.31,-2.31,2,F338S +urn:mavedb:00000044-b-2#311,NA,NA,p.Phe8Thr,-2.04,-2.01,1,F338T +urn:mavedb:00000044-b-2#312,NA,NA,p.Phe8Thr,-1.99,-2.01,2,F338T +urn:mavedb:00000044-b-2#315,NA,NA,p.Phe8Trp,-0.07,-0.06,1,F338W +urn:mavedb:00000044-b-2#316,NA,NA,p.Phe8Trp,-0.05,-0.06,2,F338W +urn:mavedb:00000044-b-2#317,NA,NA,p.Phe8Tyr,-0.3,-0.52,1,F338Y +urn:mavedb:00000044-b-2#318,NA,NA,p.Phe8Tyr,-0.74,-0.52,2,F338Y +urn:mavedb:00000044-b-2#313,NA,NA,p.Phe8Val,-1.46,-1.5,1,F338V +urn:mavedb:00000044-b-2#314,NA,NA,p.Phe8Val,-1.54,-1.5,2,F338V +urn:mavedb:00000044-b-2#3959,NA,NA,p.Phe99*,-4.62,-4.56,1,F429 +urn:mavedb:00000044-b-2#3960,NA,NA,p.Phe99*,-4.5,-4.56,2,F429 +urn:mavedb:00000044-b-2#3921,NA,NA,p.Phe99Ala,-2.92,-2.86,1,F429A +urn:mavedb:00000044-b-2#3922,NA,NA,p.Phe99Ala,-2.81,-2.86,2,F429A +urn:mavedb:00000044-b-2#3947,NA,NA,p.Phe99Arg,-3,-2.92,1,F429R +urn:mavedb:00000044-b-2#3948,NA,NA,p.Phe99Arg,-2.84,-2.92,2,F429R +urn:mavedb:00000044-b-2#3941,NA,NA,p.Phe99Asn,-3,-2.93,1,F429N +urn:mavedb:00000044-b-2#3942,NA,NA,p.Phe99Asn,-2.85,-2.93,2,F429N +urn:mavedb:00000044-b-2#3925,NA,NA,p.Phe99Asp,-3,-2.93,1,F429D +urn:mavedb:00000044-b-2#3926,NA,NA,p.Phe99Asp,-2.86,-2.93,2,F429D +urn:mavedb:00000044-b-2#3923,NA,NA,p.Phe99Cys,-2.92,-2.85,1,F429C +urn:mavedb:00000044-b-2#3924,NA,NA,p.Phe99Cys,-2.78,-2.85,2,F429C +urn:mavedb:00000044-b-2#3945,NA,NA,p.Phe99Gln,-2.93,-2.91,1,F429Q +urn:mavedb:00000044-b-2#3946,NA,NA,p.Phe99Gln,-2.88,-2.91,2,F429Q +urn:mavedb:00000044-b-2#3927,NA,NA,p.Phe99Glu,-2.92,-2.88,1,F429E +urn:mavedb:00000044-b-2#3928,NA,NA,p.Phe99Glu,-2.84,-2.88,2,F429E +urn:mavedb:00000044-b-2#3929,NA,NA,p.Phe99Gly,-2.92,-2.84,1,F429G +urn:mavedb:00000044-b-2#3930,NA,NA,p.Phe99Gly,-2.76,-2.84,2,F429G +urn:mavedb:00000044-b-2#3931,NA,NA,p.Phe99His,-2.9,-2.87,1,F429H +urn:mavedb:00000044-b-2#3932,NA,NA,p.Phe99His,-2.85,-2.87,2,F429H +urn:mavedb:00000044-b-2#3933,NA,NA,p.Phe99Ile,-2.54,-2.47,1,F429I +urn:mavedb:00000044-b-2#3934,NA,NA,p.Phe99Ile,-2.39,-2.47,2,F429I +urn:mavedb:00000044-b-2#3937,NA,NA,p.Phe99Leu,-2.21,-2.17,1,F429L +urn:mavedb:00000044-b-2#3938,NA,NA,p.Phe99Leu,-2.13,-2.17,2,F429L +urn:mavedb:00000044-b-2#3935,NA,NA,p.Phe99Lys,-2.95,-2.89,1,F429K +urn:mavedb:00000044-b-2#3936,NA,NA,p.Phe99Lys,-2.82,-2.89,2,F429K +urn:mavedb:00000044-b-2#3939,NA,NA,p.Phe99Met,-2.11,-2.15,1,F429M +urn:mavedb:00000044-b-2#3940,NA,NA,p.Phe99Met,-2.2,-2.15,2,F429M +urn:mavedb:00000044-b-2#3943,NA,NA,p.Phe99Pro,-2.97,-2.93,1,F429P +urn:mavedb:00000044-b-2#3944,NA,NA,p.Phe99Pro,-2.89,-2.93,2,F429P +urn:mavedb:00000044-b-2#3949,NA,NA,p.Phe99Ser,-2.98,-2.9,1,F429S +urn:mavedb:00000044-b-2#3950,NA,NA,p.Phe99Ser,-2.81,-2.9,2,F429S +urn:mavedb:00000044-b-2#3951,NA,NA,p.Phe99Thr,-2.99,-2.89,1,F429T +urn:mavedb:00000044-b-2#3952,NA,NA,p.Phe99Thr,-2.78,-2.89,2,F429T +urn:mavedb:00000044-b-2#3955,NA,NA,p.Phe99Trp,-0.31,-0.29,1,F429W +urn:mavedb:00000044-b-2#3956,NA,NA,p.Phe99Trp,-0.28,-0.29,2,F429W +urn:mavedb:00000044-b-2#3957,NA,NA,p.Phe99Tyr,-1.99,-1.89,1,F429Y +urn:mavedb:00000044-b-2#3958,NA,NA,p.Phe99Tyr,-1.78,-1.89,2,F429Y +urn:mavedb:00000044-b-2#3953,NA,NA,p.Phe99Val,-2.67,-2.61,1,F429V +urn:mavedb:00000044-b-2#3954,NA,NA,p.Phe99Val,-2.55,-2.61,2,F429V +urn:mavedb:00000044-b-2#5319,NA,NA,p.Pro133*,-4.6,-4.57,1,P463 +urn:mavedb:00000044-b-2#5320,NA,NA,p.Pro133*,-4.54,-4.57,2,P463 +urn:mavedb:00000044-b-2#5281,NA,NA,p.Pro133Ala,-0.51,-0.48,1,P463A +urn:mavedb:00000044-b-2#5282,NA,NA,p.Pro133Ala,-0.46,-0.48,2,P463A +urn:mavedb:00000044-b-2#5307,NA,NA,p.Pro133Arg,-2.05,-2.04,1,P463R +urn:mavedb:00000044-b-2#5308,NA,NA,p.Pro133Arg,-2.03,-2.04,2,P463R +urn:mavedb:00000044-b-2#5303,NA,NA,p.Pro133Asn,-2.22,-1.98,1,P463N +urn:mavedb:00000044-b-2#5304,NA,NA,p.Pro133Asn,-1.75,-1.98,2,P463N +urn:mavedb:00000044-b-2#5285,NA,NA,p.Pro133Asp,-1.87,-1.71,1,P463D +urn:mavedb:00000044-b-2#5286,NA,NA,p.Pro133Asp,-1.54,-1.71,2,P463D +urn:mavedb:00000044-b-2#5283,NA,NA,p.Pro133Cys,-1.5,-1.62,1,P463C +urn:mavedb:00000044-b-2#5284,NA,NA,p.Pro133Cys,-1.74,-1.62,2,P463C +urn:mavedb:00000044-b-2#5305,NA,NA,p.Pro133Gln,-1.63,-1.67,1,P463Q +urn:mavedb:00000044-b-2#5306,NA,NA,p.Pro133Gln,-1.71,-1.67,2,P463Q +urn:mavedb:00000044-b-2#5287,NA,NA,p.Pro133Glu,-1.39,-1.23,1,P463E +urn:mavedb:00000044-b-2#5288,NA,NA,p.Pro133Glu,-1.06,-1.23,2,P463E +urn:mavedb:00000044-b-2#5291,NA,NA,p.Pro133Gly,-1.25,-1.11,1,P463G +urn:mavedb:00000044-b-2#5292,NA,NA,p.Pro133Gly,-0.97,-1.11,2,P463G +urn:mavedb:00000044-b-2#5293,NA,NA,p.Pro133His,-1.86,-1.82,1,P463H +urn:mavedb:00000044-b-2#5294,NA,NA,p.Pro133His,-1.77,-1.82,2,P463H +urn:mavedb:00000044-b-2#5295,NA,NA,p.Pro133Ile,-1.71,-1.76,1,P463I +urn:mavedb:00000044-b-2#5296,NA,NA,p.Pro133Ile,-1.8,-1.76,2,P463I +urn:mavedb:00000044-b-2#5299,NA,NA,p.Pro133Leu,-1.96,-1.9,1,P463L +urn:mavedb:00000044-b-2#5300,NA,NA,p.Pro133Leu,-1.85,-1.9,2,P463L +urn:mavedb:00000044-b-2#5297,NA,NA,p.Pro133Lys,-1.95,-1.94,1,P463K +urn:mavedb:00000044-b-2#5298,NA,NA,p.Pro133Lys,-1.92,-1.94,2,P463K +urn:mavedb:00000044-b-2#5301,NA,NA,p.Pro133Met,-1.79,-1.82,1,P463M +urn:mavedb:00000044-b-2#5302,NA,NA,p.Pro133Met,-1.85,-1.82,2,P463M +urn:mavedb:00000044-b-2#5289,NA,NA,p.Pro133Phe,-1.49,-1.67,1,P463F +urn:mavedb:00000044-b-2#5290,NA,NA,p.Pro133Phe,-1.85,-1.67,2,P463F +urn:mavedb:00000044-b-2#5309,NA,NA,p.Pro133Ser,-1.16,-1.06,1,P463S +urn:mavedb:00000044-b-2#5310,NA,NA,p.Pro133Ser,-0.95,-1.06,2,P463S +urn:mavedb:00000044-b-2#5311,NA,NA,p.Pro133Thr,-1.79,-1.81,1,P463T +urn:mavedb:00000044-b-2#5312,NA,NA,p.Pro133Thr,-1.82,-1.81,2,P463T +urn:mavedb:00000044-b-2#5315,NA,NA,p.Pro133Trp,-0.05,-0.81,1,P463W +urn:mavedb:00000044-b-2#5316,NA,NA,p.Pro133Trp,-1.57,-0.81,2,P463W +urn:mavedb:00000044-b-2#5317,NA,NA,p.Pro133Tyr,-1.86,-1.81,1,P463Y +urn:mavedb:00000044-b-2#5318,NA,NA,p.Pro133Tyr,-1.75,-1.81,2,P463Y +urn:mavedb:00000044-b-2#5313,NA,NA,p.Pro133Val,-1.57,-1.58,1,P463V +urn:mavedb:00000044-b-2#5314,NA,NA,p.Pro133Val,-1.6,-1.58,2,P463V +urn:mavedb:00000044-b-2#5959,NA,NA,p.Pro149*,-4.6,-4.57,1,P479 +urn:mavedb:00000044-b-2#5960,NA,NA,p.Pro149*,-4.54,-4.57,2,P479 +urn:mavedb:00000044-b-2#5921,NA,NA,p.Pro149Ala,-0.21,-0.17,1,P479A +urn:mavedb:00000044-b-2#5922,NA,NA,p.Pro149Ala,-0.13,-0.17,2,P479A +urn:mavedb:00000044-b-2#5947,NA,NA,p.Pro149Arg,-0.19,-0.24,1,P479R +urn:mavedb:00000044-b-2#5948,NA,NA,p.Pro149Arg,-0.29,-0.24,2,P479R +urn:mavedb:00000044-b-2#5943,NA,NA,p.Pro149Asn,-0.23,-0.23,1,P479N +urn:mavedb:00000044-b-2#5944,NA,NA,p.Pro149Asn,-0.23,-0.23,2,P479N +urn:mavedb:00000044-b-2#5925,NA,NA,p.Pro149Asp,-0.04,-0.06,1,P479D +urn:mavedb:00000044-b-2#5926,NA,NA,p.Pro149Asp,-0.08,-0.06,2,P479D +urn:mavedb:00000044-b-2#5923,NA,NA,p.Pro149Cys,-0.67,-0.62,1,P479C +urn:mavedb:00000044-b-2#5924,NA,NA,p.Pro149Cys,-0.57,-0.62,2,P479C +urn:mavedb:00000044-b-2#5945,NA,NA,p.Pro149Gln,-0.17,-0.16,1,P479Q +urn:mavedb:00000044-b-2#5946,NA,NA,p.Pro149Gln,-0.15,-0.16,2,P479Q +urn:mavedb:00000044-b-2#5927,NA,NA,p.Pro149Glu,-0.1,-0.16,1,P479E +urn:mavedb:00000044-b-2#5928,NA,NA,p.Pro149Glu,-0.22,-0.16,2,P479E +urn:mavedb:00000044-b-2#5931,NA,NA,p.Pro149Gly,-0.42,-0.44,1,P479G +urn:mavedb:00000044-b-2#5932,NA,NA,p.Pro149Gly,-0.45,-0.44,2,P479G +urn:mavedb:00000044-b-2#5933,NA,NA,p.Pro149His,-0.29,-0.32,1,P479H +urn:mavedb:00000044-b-2#5934,NA,NA,p.Pro149His,-0.35,-0.32,2,P479H +urn:mavedb:00000044-b-2#5935,NA,NA,p.Pro149Ile,-0.33,-0.37,1,P479I +urn:mavedb:00000044-b-2#5936,NA,NA,p.Pro149Ile,-0.41,-0.37,2,P479I +urn:mavedb:00000044-b-2#5939,NA,NA,p.Pro149Leu,-0.37,-0.35,1,P479L +urn:mavedb:00000044-b-2#5940,NA,NA,p.Pro149Leu,-0.33,-0.35,2,P479L +urn:mavedb:00000044-b-2#5937,NA,NA,p.Pro149Lys,-0.11,-0.11,1,P479K +urn:mavedb:00000044-b-2#5938,NA,NA,p.Pro149Lys,-0.11,-0.11,2,P479K +urn:mavedb:00000044-b-2#5941,NA,NA,p.Pro149Met,-0.32,-0.3,1,P479M +urn:mavedb:00000044-b-2#5942,NA,NA,p.Pro149Met,-0.27,-0.3,2,P479M +urn:mavedb:00000044-b-2#5929,NA,NA,p.Pro149Phe,-0.55,-0.73,1,P479F +urn:mavedb:00000044-b-2#5930,NA,NA,p.Pro149Phe,-0.91,-0.73,2,P479F +urn:mavedb:00000044-b-2#5949,NA,NA,p.Pro149Ser,-0.17,-0.2,1,P479S +urn:mavedb:00000044-b-2#5950,NA,NA,p.Pro149Ser,-0.23,-0.2,2,P479S +urn:mavedb:00000044-b-2#5951,NA,NA,p.Pro149Thr,-0.24,-0.29,1,P479T +urn:mavedb:00000044-b-2#5952,NA,NA,p.Pro149Thr,-0.34,-0.29,2,P479T +urn:mavedb:00000044-b-2#5955,NA,NA,p.Pro149Trp,-1.25,-1.31,1,P479W +urn:mavedb:00000044-b-2#5956,NA,NA,p.Pro149Trp,-1.38,-1.31,2,P479W +urn:mavedb:00000044-b-2#5957,NA,NA,p.Pro149Tyr,-0.44,-0.49,1,P479Y +urn:mavedb:00000044-b-2#5958,NA,NA,p.Pro149Tyr,-0.55,-0.49,2,P479Y +urn:mavedb:00000044-b-2#5953,NA,NA,p.Pro149Val,-0.41,-0.33,1,P479V +urn:mavedb:00000044-b-2#5954,NA,NA,p.Pro149Val,-0.24,-0.33,2,P479V +urn:mavedb:00000044-b-2#6439,NA,NA,p.Pro161*,-4.61,-4.56,1,P491 +urn:mavedb:00000044-b-2#6440,NA,NA,p.Pro161*,-4.52,-4.56,2,P491 +urn:mavedb:00000044-b-2#6401,NA,NA,p.Pro161Ala,-1.4,-1.54,1,P491A +urn:mavedb:00000044-b-2#6402,NA,NA,p.Pro161Ala,-1.68,-1.54,2,P491A +urn:mavedb:00000044-b-2#6427,NA,NA,p.Pro161Arg,-2.5,-2.44,1,P491R +urn:mavedb:00000044-b-2#6428,NA,NA,p.Pro161Arg,-2.38,-2.44,2,P491R +urn:mavedb:00000044-b-2#6423,NA,NA,p.Pro161Asn,-1.95,-1.9,1,P491N +urn:mavedb:00000044-b-2#6424,NA,NA,p.Pro161Asn,-1.85,-1.9,2,P491N +urn:mavedb:00000044-b-2#6405,NA,NA,p.Pro161Asp,-1.95,-1.89,1,P491D +urn:mavedb:00000044-b-2#6406,NA,NA,p.Pro161Asp,-1.84,-1.89,2,P491D +urn:mavedb:00000044-b-2#6403,NA,NA,p.Pro161Cys,-2.07,-1.89,1,P491C +urn:mavedb:00000044-b-2#6404,NA,NA,p.Pro161Cys,-1.7,-1.89,2,P491C +urn:mavedb:00000044-b-2#6425,NA,NA,p.Pro161Gln,-2.13,-1.99,1,P491Q +urn:mavedb:00000044-b-2#6426,NA,NA,p.Pro161Gln,-1.86,-1.99,2,P491Q +urn:mavedb:00000044-b-2#6407,NA,NA,p.Pro161Glu,-2.12,-2.04,1,P491E +urn:mavedb:00000044-b-2#6408,NA,NA,p.Pro161Glu,-1.95,-2.04,2,P491E +urn:mavedb:00000044-b-2#6411,NA,NA,p.Pro161Gly,-1.55,-1.75,1,P491G +urn:mavedb:00000044-b-2#6412,NA,NA,p.Pro161Gly,-1.94,-1.75,2,P491G +urn:mavedb:00000044-b-2#6413,NA,NA,p.Pro161His,-2.56,-2.33,1,P491H +urn:mavedb:00000044-b-2#6414,NA,NA,p.Pro161His,-2.09,-2.33,2,P491H +urn:mavedb:00000044-b-2#6415,NA,NA,p.Pro161Ile,-2.53,-2.46,1,P491I +urn:mavedb:00000044-b-2#6416,NA,NA,p.Pro161Ile,-2.39,-2.46,2,P491I +urn:mavedb:00000044-b-2#6419,NA,NA,p.Pro161Leu,-2.47,-2.43,1,P491L +urn:mavedb:00000044-b-2#6420,NA,NA,p.Pro161Leu,-2.39,-2.43,2,P491L +urn:mavedb:00000044-b-2#6417,NA,NA,p.Pro161Lys,-2.48,-2.61,1,P491K +urn:mavedb:00000044-b-2#6418,NA,NA,p.Pro161Lys,-2.74,-2.61,2,P491K +urn:mavedb:00000044-b-2#6421,NA,NA,p.Pro161Met,-2.54,-2.38,1,P491M +urn:mavedb:00000044-b-2#6422,NA,NA,p.Pro161Met,-2.23,-2.38,2,P491M +urn:mavedb:00000044-b-2#6409,NA,NA,p.Pro161Phe,-2.5,-2.47,1,P491F +urn:mavedb:00000044-b-2#6410,NA,NA,p.Pro161Phe,-2.44,-2.47,2,P491F +urn:mavedb:00000044-b-2#6429,NA,NA,p.Pro161Ser,-1.56,-1.49,1,P491S +urn:mavedb:00000044-b-2#6430,NA,NA,p.Pro161Ser,-1.43,-1.49,2,P491S +urn:mavedb:00000044-b-2#6431,NA,NA,p.Pro161Thr,-1.72,-1.64,1,P491T +urn:mavedb:00000044-b-2#6432,NA,NA,p.Pro161Thr,-1.55,-1.64,2,P491T +urn:mavedb:00000044-b-2#6435,NA,NA,p.Pro161Trp,-2.14,-2.26,1,P491W +urn:mavedb:00000044-b-2#6436,NA,NA,p.Pro161Trp,-2.38,-2.26,2,P491W +urn:mavedb:00000044-b-2#6437,NA,NA,p.Pro161Tyr,-2.62,-2.54,1,P491Y +urn:mavedb:00000044-b-2#6438,NA,NA,p.Pro161Tyr,-2.46,-2.54,2,P491Y +urn:mavedb:00000044-b-2#6433,NA,NA,p.Pro161Val,-2.34,-2.34,1,P491V +urn:mavedb:00000044-b-2#6434,NA,NA,p.Pro161Val,-2.33,-2.34,2,P491V +urn:mavedb:00000044-b-2#6759,NA,NA,p.Pro169*,-4.63,-4.57,1,P499 +urn:mavedb:00000044-b-2#6760,NA,NA,p.Pro169*,-4.5,-4.57,2,P499 +urn:mavedb:00000044-b-2#6721,NA,NA,p.Pro169Ala,-0.85,-0.52,1,P499A +urn:mavedb:00000044-b-2#6722,NA,NA,p.Pro169Ala,-0.19,-0.52,2,P499A +urn:mavedb:00000044-b-2#6747,NA,NA,p.Pro169Arg,-0.53,-0.58,1,P499R +urn:mavedb:00000044-b-2#6748,NA,NA,p.Pro169Arg,-0.63,-0.58,2,P499R +urn:mavedb:00000044-b-2#6743,NA,NA,p.Pro169Asn,-0.27,-0.34,1,P499N +urn:mavedb:00000044-b-2#6744,NA,NA,p.Pro169Asn,-0.41,-0.34,2,P499N +urn:mavedb:00000044-b-2#6725,NA,NA,p.Pro169Asp,-0.19,-0.21,1,P499D +urn:mavedb:00000044-b-2#6726,NA,NA,p.Pro169Asp,-0.22,-0.21,2,P499D +urn:mavedb:00000044-b-2#6723,NA,NA,p.Pro169Cys,-1.14,-0.83,1,P499C +urn:mavedb:00000044-b-2#6724,NA,NA,p.Pro169Cys,-0.52,-0.83,2,P499C +urn:mavedb:00000044-b-2#6745,NA,NA,p.Pro169Gln,-0.46,-0.27,1,P499Q +urn:mavedb:00000044-b-2#6746,NA,NA,p.Pro169Gln,-0.07,-0.27,2,P499Q +urn:mavedb:00000044-b-2#6727,NA,NA,p.Pro169Glu,0,-0.06,1,P499E +urn:mavedb:00000044-b-2#6728,NA,NA,p.Pro169Glu,-0.12,-0.06,2,P499E +urn:mavedb:00000044-b-2#6731,NA,NA,p.Pro169Gly,-0.23,-0.23,1,P499G +urn:mavedb:00000044-b-2#6732,NA,NA,p.Pro169Gly,-0.24,-0.23,2,P499G +urn:mavedb:00000044-b-2#6733,NA,NA,p.Pro169His,-0.37,-0.51,1,P499H +urn:mavedb:00000044-b-2#6734,NA,NA,p.Pro169His,-0.66,-0.51,2,P499H +urn:mavedb:00000044-b-2#6735,NA,NA,p.Pro169Ile,-1.47,-1.07,1,P499I +urn:mavedb:00000044-b-2#6736,NA,NA,p.Pro169Ile,-0.67,-1.07,2,P499I +urn:mavedb:00000044-b-2#6739,NA,NA,p.Pro169Leu,-0.64,-0.61,1,P499L +urn:mavedb:00000044-b-2#6740,NA,NA,p.Pro169Leu,-0.58,-0.61,2,P499L +urn:mavedb:00000044-b-2#6737,NA,NA,p.Pro169Lys,-0.67,-0.41,1,P499K +urn:mavedb:00000044-b-2#6738,NA,NA,p.Pro169Lys,-0.15,-0.41,2,P499K +urn:mavedb:00000044-b-2#6741,NA,NA,p.Pro169Met,-0.67,-0.53,1,P499M +urn:mavedb:00000044-b-2#6742,NA,NA,p.Pro169Met,-0.39,-0.53,2,P499M +urn:mavedb:00000044-b-2#6729,NA,NA,p.Pro169Phe,-1.02,-0.94,1,P499F +urn:mavedb:00000044-b-2#6730,NA,NA,p.Pro169Phe,-0.87,-0.94,2,P499F +urn:mavedb:00000044-b-2#6749,NA,NA,p.Pro169Ser,-0.13,-0.24,1,P499S +urn:mavedb:00000044-b-2#6750,NA,NA,p.Pro169Ser,-0.35,-0.24,2,P499S +urn:mavedb:00000044-b-2#6751,NA,NA,p.Pro169Thr,-0.46,-0.35,1,P499T +urn:mavedb:00000044-b-2#6752,NA,NA,p.Pro169Thr,-0.25,-0.35,2,P499T +urn:mavedb:00000044-b-2#6755,NA,NA,p.Pro169Trp,-1.74,-1.08,1,P499W +urn:mavedb:00000044-b-2#6756,NA,NA,p.Pro169Trp,-0.41,-1.08,2,P499W +urn:mavedb:00000044-b-2#6757,NA,NA,p.Pro169Tyr,-0.73,-0.58,1,P499Y +urn:mavedb:00000044-b-2#6758,NA,NA,p.Pro169Tyr,-0.42,-0.58,2,P499Y +urn:mavedb:00000044-b-2#6753,NA,NA,p.Pro169Val,-0.38,-0.41,1,P499V +urn:mavedb:00000044-b-2#6754,NA,NA,p.Pro169Val,-0.44,-0.41,2,P499V +urn:mavedb:00000044-b-2#7079,NA,NA,p.Pro177*,-4.62,-4.62,1,P507 +urn:mavedb:00000044-b-2#7080,NA,NA,p.Pro177*,-4.61,-4.62,2,P507 +urn:mavedb:00000044-b-2#7041,NA,NA,p.Pro177Ala,-0.98,-0.88,1,P507A +urn:mavedb:00000044-b-2#7042,NA,NA,p.Pro177Ala,-0.77,-0.88,2,P507A +urn:mavedb:00000044-b-2#7067,NA,NA,p.Pro177Arg,-2.9,-2.8,1,P507R +urn:mavedb:00000044-b-2#7068,NA,NA,p.Pro177Arg,-2.7,-2.8,2,P507R +urn:mavedb:00000044-b-2#7063,NA,NA,p.Pro177Asn,-2.7,-2.62,1,P507N +urn:mavedb:00000044-b-2#7064,NA,NA,p.Pro177Asn,-2.54,-2.62,2,P507N +urn:mavedb:00000044-b-2#7045,NA,NA,p.Pro177Asp,-2.4,-2.46,1,P507D +urn:mavedb:00000044-b-2#7046,NA,NA,p.Pro177Asp,-2.51,-2.46,2,P507D +urn:mavedb:00000044-b-2#7043,NA,NA,p.Pro177Cys,-2.27,-2.2,1,P507C +urn:mavedb:00000044-b-2#7044,NA,NA,p.Pro177Cys,-2.14,-2.2,2,P507C +urn:mavedb:00000044-b-2#7065,NA,NA,p.Pro177Gln,-2.54,-2.49,1,P507Q +urn:mavedb:00000044-b-2#7066,NA,NA,p.Pro177Gln,-2.44,-2.49,2,P507Q +urn:mavedb:00000044-b-2#7047,NA,NA,p.Pro177Glu,-2.29,-2.39,1,P507E +urn:mavedb:00000044-b-2#7048,NA,NA,p.Pro177Glu,-2.49,-2.39,2,P507E +urn:mavedb:00000044-b-2#7051,NA,NA,p.Pro177Gly,-2.68,-2.57,1,P507G +urn:mavedb:00000044-b-2#7052,NA,NA,p.Pro177Gly,-2.45,-2.57,2,P507G +urn:mavedb:00000044-b-2#7053,NA,NA,p.Pro177His,-2.79,-2.62,1,P507H +urn:mavedb:00000044-b-2#7054,NA,NA,p.Pro177His,-2.45,-2.62,2,P507H +urn:mavedb:00000044-b-2#7055,NA,NA,p.Pro177Ile,-2.44,-2.43,1,P507I +urn:mavedb:00000044-b-2#7056,NA,NA,p.Pro177Ile,-2.42,-2.43,2,P507I +urn:mavedb:00000044-b-2#7059,NA,NA,p.Pro177Leu,-1.83,-1.83,1,P507L +urn:mavedb:00000044-b-2#7060,NA,NA,p.Pro177Leu,-1.82,-1.83,2,P507L +urn:mavedb:00000044-b-2#7057,NA,NA,p.Pro177Lys,-2.51,-2.34,1,P507K +urn:mavedb:00000044-b-2#7058,NA,NA,p.Pro177Lys,-2.17,-2.34,2,P507K +urn:mavedb:00000044-b-2#7061,NA,NA,p.Pro177Met,-2.25,-2.05,1,P507M +urn:mavedb:00000044-b-2#7062,NA,NA,p.Pro177Met,-1.84,-2.05,2,P507M +urn:mavedb:00000044-b-2#7049,NA,NA,p.Pro177Phe,-2.17,-2.18,1,P507F +urn:mavedb:00000044-b-2#7050,NA,NA,p.Pro177Phe,-2.19,-2.18,2,P507F +urn:mavedb:00000044-b-2#7069,NA,NA,p.Pro177Ser,-2,-1.7,1,P507S +urn:mavedb:00000044-b-2#7070,NA,NA,p.Pro177Ser,-1.39,-1.7,2,P507S +urn:mavedb:00000044-b-2#7071,NA,NA,p.Pro177Thr,-2.43,-2.41,1,P507T +urn:mavedb:00000044-b-2#7072,NA,NA,p.Pro177Thr,-2.4,-2.41,2,P507T +urn:mavedb:00000044-b-2#7075,NA,NA,p.Pro177Trp,-2.17,-2.07,1,P507W +urn:mavedb:00000044-b-2#7076,NA,NA,p.Pro177Trp,-1.98,-2.07,2,P507W +urn:mavedb:00000044-b-2#7077,NA,NA,p.Pro177Tyr,-2.34,-2.24,1,P507Y +urn:mavedb:00000044-b-2#7078,NA,NA,p.Pro177Tyr,-2.14,-2.24,2,P507Y +urn:mavedb:00000044-b-2#7073,NA,NA,p.Pro177Val,-2.57,-2.5,1,P507V +urn:mavedb:00000044-b-2#7074,NA,NA,p.Pro177Val,-2.44,-2.5,2,P507V +urn:mavedb:00000044-b-2#7639,NA,NA,p.Pro191*,-3.1,-3.01,1,P521 +urn:mavedb:00000044-b-2#7640,NA,NA,p.Pro191*,-2.93,-3.01,2,P521 +urn:mavedb:00000044-b-2#7601,NA,NA,p.Pro191Ala,0,-1.43,1,P521A +urn:mavedb:00000044-b-2#7602,NA,NA,p.Pro191Ala,-2.87,-1.43,2,P521A +urn:mavedb:00000044-b-2#7627,NA,NA,p.Pro191Arg,-0.04,-0.16,1,P521R +urn:mavedb:00000044-b-2#7628,NA,NA,p.Pro191Arg,-0.28,-0.16,2,P521R +urn:mavedb:00000044-b-2#7623,NA,NA,p.Pro191Asn,0.35,0.25,1,P521N +urn:mavedb:00000044-b-2#7624,NA,NA,p.Pro191Asn,0.15,0.25,2,P521N +urn:mavedb:00000044-b-2#7605,NA,NA,p.Pro191Asp,-0.02,-0.09,1,P521D +urn:mavedb:00000044-b-2#7606,NA,NA,p.Pro191Asp,-0.17,-0.09,2,P521D +urn:mavedb:00000044-b-2#7603,NA,NA,p.Pro191Cys,-0.82,-0.57,1,P521C +urn:mavedb:00000044-b-2#7604,NA,NA,p.Pro191Cys,-0.31,-0.57,2,P521C +urn:mavedb:00000044-b-2#7625,NA,NA,p.Pro191Gln,-2.32,-1.12,1,P521Q +urn:mavedb:00000044-b-2#7626,NA,NA,p.Pro191Gln,0.08,-1.12,2,P521Q +urn:mavedb:00000044-b-2#7607,NA,NA,p.Pro191Glu,-3.01,-1.37,1,P521E +urn:mavedb:00000044-b-2#7608,NA,NA,p.Pro191Glu,0.28,-1.37,2,P521E +urn:mavedb:00000044-b-2#7611,NA,NA,p.Pro191Gly,-0.36,-0.17,1,P521G +urn:mavedb:00000044-b-2#7612,NA,NA,p.Pro191Gly,0.01,-0.17,2,P521G +urn:mavedb:00000044-b-2#7613,NA,NA,p.Pro191His,-0.11,-0.19,1,P521H +urn:mavedb:00000044-b-2#7614,NA,NA,p.Pro191His,-0.26,-0.19,2,P521H +urn:mavedb:00000044-b-2#7615,NA,NA,p.Pro191Ile,-1.2,-1.14,1,P521I +urn:mavedb:00000044-b-2#7616,NA,NA,p.Pro191Ile,-1.08,-1.14,2,P521I +urn:mavedb:00000044-b-2#7619,NA,NA,p.Pro191Leu,-1.67,-1.31,1,P521L +urn:mavedb:00000044-b-2#7620,NA,NA,p.Pro191Leu,-0.95,-1.31,2,P521L +urn:mavedb:00000044-b-2#7617,NA,NA,p.Pro191Lys,-0.52,-0.54,1,P521K +urn:mavedb:00000044-b-2#7618,NA,NA,p.Pro191Lys,-0.56,-0.54,2,P521K +urn:mavedb:00000044-b-2#7621,NA,NA,p.Pro191Met,-2.98,-2.74,1,P521M +urn:mavedb:00000044-b-2#7622,NA,NA,p.Pro191Met,-2.51,-2.74,2,P521M +urn:mavedb:00000044-b-2#7609,NA,NA,p.Pro191Phe,-0.88,-0.77,1,P521F +urn:mavedb:00000044-b-2#7610,NA,NA,p.Pro191Phe,-0.66,-0.77,2,P521F +urn:mavedb:00000044-b-2#7629,NA,NA,p.Pro191Ser,-0.09,-0.06,1,P521S +urn:mavedb:00000044-b-2#7630,NA,NA,p.Pro191Ser,-0.04,-0.06,2,P521S +urn:mavedb:00000044-b-2#7631,NA,NA,p.Pro191Thr,-0.09,-0.14,1,P521T +urn:mavedb:00000044-b-2#7632,NA,NA,p.Pro191Thr,-0.19,-0.14,2,P521T +urn:mavedb:00000044-b-2#7635,NA,NA,p.Pro191Trp,-0.86,-1.87,1,P521W +urn:mavedb:00000044-b-2#7636,NA,NA,p.Pro191Trp,-2.88,-1.87,2,P521W +urn:mavedb:00000044-b-2#7637,NA,NA,p.Pro191Tyr,-0.95,-1.88,1,P521Y +urn:mavedb:00000044-b-2#7638,NA,NA,p.Pro191Tyr,-2.81,-1.88,2,P521Y +urn:mavedb:00000044-b-2#7633,NA,NA,p.Pro191Val,-0.33,-0.84,1,P521V +urn:mavedb:00000044-b-2#7634,NA,NA,p.Pro191Val,-1.35,-0.84,2,P521V +urn:mavedb:00000044-b-2#7879,NA,NA,p.Pro197*,-4.6,-4.56,1,P527 +urn:mavedb:00000044-b-2#7880,NA,NA,p.Pro197*,-4.52,-4.56,2,P527 +urn:mavedb:00000044-b-2#7841,NA,NA,p.Pro197Ala,0.26,0.25,1,P527A +urn:mavedb:00000044-b-2#7842,NA,NA,p.Pro197Ala,0.25,0.25,2,P527A +urn:mavedb:00000044-b-2#7867,NA,NA,p.Pro197Arg,0.06,0.19,1,P527R +urn:mavedb:00000044-b-2#7868,NA,NA,p.Pro197Arg,0.32,0.19,2,P527R +urn:mavedb:00000044-b-2#7863,NA,NA,p.Pro197Asn,0.05,0.05,1,P527N +urn:mavedb:00000044-b-2#7864,NA,NA,p.Pro197Asn,0.06,0.05,2,P527N +urn:mavedb:00000044-b-2#7845,NA,NA,p.Pro197Asp,-0.01,0.19,1,P527D +urn:mavedb:00000044-b-2#7846,NA,NA,p.Pro197Asp,0.38,0.19,2,P527D +urn:mavedb:00000044-b-2#7843,NA,NA,p.Pro197Cys,0.07,0.3,1,P527C +urn:mavedb:00000044-b-2#7844,NA,NA,p.Pro197Cys,0.53,0.3,2,P527C +urn:mavedb:00000044-b-2#7865,NA,NA,p.Pro197Gln,0.1,0.08,1,P527Q +urn:mavedb:00000044-b-2#7866,NA,NA,p.Pro197Gln,0.07,0.08,2,P527Q +urn:mavedb:00000044-b-2#7847,NA,NA,p.Pro197Glu,-0.04,-0.05,1,P527E +urn:mavedb:00000044-b-2#7848,NA,NA,p.Pro197Glu,-0.05,-0.05,2,P527E +urn:mavedb:00000044-b-2#7851,NA,NA,p.Pro197Gly,0.08,0.01,1,P527G +urn:mavedb:00000044-b-2#7852,NA,NA,p.Pro197Gly,-0.06,0.01,2,P527G +urn:mavedb:00000044-b-2#7853,NA,NA,p.Pro197His,0.09,0.07,1,P527H +urn:mavedb:00000044-b-2#7854,NA,NA,p.Pro197His,0.06,0.07,2,P527H +urn:mavedb:00000044-b-2#7855,NA,NA,p.Pro197Ile,0.08,0.22,1,P527I +urn:mavedb:00000044-b-2#7856,NA,NA,p.Pro197Ile,0.36,0.22,2,P527I +urn:mavedb:00000044-b-2#7859,NA,NA,p.Pro197Leu,0.23,0.41,1,P527L +urn:mavedb:00000044-b-2#7860,NA,NA,p.Pro197Leu,0.6,0.41,2,P527L +urn:mavedb:00000044-b-2#7857,NA,NA,p.Pro197Lys,0.26,0.34,1,P527K +urn:mavedb:00000044-b-2#7858,NA,NA,p.Pro197Lys,0.42,0.34,2,P527K +urn:mavedb:00000044-b-2#7861,NA,NA,p.Pro197Met,0.3,0.21,1,P527M +urn:mavedb:00000044-b-2#7862,NA,NA,p.Pro197Met,0.12,0.21,2,P527M +urn:mavedb:00000044-b-2#7849,NA,NA,p.Pro197Phe,0.13,0.01,1,P527F +urn:mavedb:00000044-b-2#7850,NA,NA,p.Pro197Phe,-0.12,0.01,2,P527F +urn:mavedb:00000044-b-2#7869,NA,NA,p.Pro197Ser,0.08,0.12,1,P527S +urn:mavedb:00000044-b-2#7870,NA,NA,p.Pro197Ser,0.16,0.12,2,P527S +urn:mavedb:00000044-b-2#7871,NA,NA,p.Pro197Thr,0.19,0.16,1,P527T +urn:mavedb:00000044-b-2#7872,NA,NA,p.Pro197Thr,0.13,0.16,2,P527T +urn:mavedb:00000044-b-2#7875,NA,NA,p.Pro197Trp,0.37,0.19,1,P527W +urn:mavedb:00000044-b-2#7876,NA,NA,p.Pro197Trp,0.01,0.19,2,P527W +urn:mavedb:00000044-b-2#7877,NA,NA,p.Pro197Tyr,0.17,0.09,1,P527Y +urn:mavedb:00000044-b-2#7878,NA,NA,p.Pro197Tyr,0.02,0.09,2,P527Y +urn:mavedb:00000044-b-2#7873,NA,NA,p.Pro197Val,0.17,0.16,1,P527V +urn:mavedb:00000044-b-2#7874,NA,NA,p.Pro197Val,0.15,0.16,2,P527V +urn:mavedb:00000044-b-2#2159,NA,NA,p.Pro54*,-4.59,-4.56,1,P384 +urn:mavedb:00000044-b-2#2160,NA,NA,p.Pro54*,-4.53,-4.56,2,P384 +urn:mavedb:00000044-b-2#2121,NA,NA,p.Pro54Ala,-0.03,0.03,1,P384A +urn:mavedb:00000044-b-2#2122,NA,NA,p.Pro54Ala,0.1,0.03,2,P384A +urn:mavedb:00000044-b-2#2147,NA,NA,p.Pro54Arg,-0.04,-0.02,1,P384R +urn:mavedb:00000044-b-2#2148,NA,NA,p.Pro54Arg,0.01,-0.02,2,P384R +urn:mavedb:00000044-b-2#2143,NA,NA,p.Pro54Asn,-0.54,-0.55,1,P384N +urn:mavedb:00000044-b-2#2144,NA,NA,p.Pro54Asn,-0.55,-0.55,2,P384N +urn:mavedb:00000044-b-2#2125,NA,NA,p.Pro54Asp,-1.79,-1.48,1,P384D +urn:mavedb:00000044-b-2#2126,NA,NA,p.Pro54Asp,-1.17,-1.48,2,P384D +urn:mavedb:00000044-b-2#2123,NA,NA,p.Pro54Cys,-1.65,-1.47,1,P384C +urn:mavedb:00000044-b-2#2124,NA,NA,p.Pro54Cys,-1.28,-1.47,2,P384C +urn:mavedb:00000044-b-2#2145,NA,NA,p.Pro54Gln,-0.09,-0.1,1,P384Q +urn:mavedb:00000044-b-2#2146,NA,NA,p.Pro54Gln,-0.11,-0.1,2,P384Q +urn:mavedb:00000044-b-2#2127,NA,NA,p.Pro54Glu,-0.11,-0.1,1,P384E +urn:mavedb:00000044-b-2#2128,NA,NA,p.Pro54Glu,-0.08,-0.1,2,P384E +urn:mavedb:00000044-b-2#2131,NA,NA,p.Pro54Gly,-0.82,-0.6,1,P384G +urn:mavedb:00000044-b-2#2132,NA,NA,p.Pro54Gly,-0.39,-0.6,2,P384G +urn:mavedb:00000044-b-2#2133,NA,NA,p.Pro54His,-0.31,-0.29,1,P384H +urn:mavedb:00000044-b-2#2134,NA,NA,p.Pro54His,-0.28,-0.29,2,P384H +urn:mavedb:00000044-b-2#2135,NA,NA,p.Pro54Ile,-0.15,-0.07,1,P384I +urn:mavedb:00000044-b-2#2136,NA,NA,p.Pro54Ile,0.02,-0.07,2,P384I +urn:mavedb:00000044-b-2#2139,NA,NA,p.Pro54Leu,-0.03,-0.03,1,P384L +urn:mavedb:00000044-b-2#2140,NA,NA,p.Pro54Leu,-0.04,-0.03,2,P384L +urn:mavedb:00000044-b-2#2137,NA,NA,p.Pro54Lys,0.24,0.18,1,P384K +urn:mavedb:00000044-b-2#2138,NA,NA,p.Pro54Lys,0.12,0.18,2,P384K +urn:mavedb:00000044-b-2#2141,NA,NA,p.Pro54Met,0,0.06,1,P384M +urn:mavedb:00000044-b-2#2142,NA,NA,p.Pro54Met,0.12,0.06,2,P384M +urn:mavedb:00000044-b-2#2129,NA,NA,p.Pro54Phe,-0.14,-0.43,1,P384F +urn:mavedb:00000044-b-2#2130,NA,NA,p.Pro54Phe,-0.72,-0.43,2,P384F +urn:mavedb:00000044-b-2#2149,NA,NA,p.Pro54Ser,-0.41,-0.38,1,P384S +urn:mavedb:00000044-b-2#2150,NA,NA,p.Pro54Ser,-0.36,-0.38,2,P384S +urn:mavedb:00000044-b-2#2151,NA,NA,p.Pro54Thr,-0.37,-0.35,1,P384T +urn:mavedb:00000044-b-2#2152,NA,NA,p.Pro54Thr,-0.32,-0.35,2,P384T +urn:mavedb:00000044-b-2#2155,NA,NA,p.Pro54Trp,-0.08,-0.11,1,P384W +urn:mavedb:00000044-b-2#2156,NA,NA,p.Pro54Trp,-0.15,-0.11,2,P384W +urn:mavedb:00000044-b-2#2157,NA,NA,p.Pro54Tyr,-0.52,-0.39,1,P384Y +urn:mavedb:00000044-b-2#2158,NA,NA,p.Pro54Tyr,-0.27,-0.39,2,P384Y +urn:mavedb:00000044-b-2#2153,NA,NA,p.Pro54Val,-0.12,-0.11,1,P384V +urn:mavedb:00000044-b-2#2154,NA,NA,p.Pro54Val,-0.1,-0.11,2,P384V +urn:mavedb:00000044-b-2#279,NA,NA,p.Pro7*,-4.65,-4.62,1,P337 +urn:mavedb:00000044-b-2#280,NA,NA,p.Pro7*,-4.59,-4.62,2,P337 +urn:mavedb:00000044-b-2#241,NA,NA,p.Pro7Ala,-0.24,-0.31,1,P337A +urn:mavedb:00000044-b-2#242,NA,NA,p.Pro7Ala,-0.37,-0.31,2,P337A +urn:mavedb:00000044-b-2#267,NA,NA,p.Pro7Arg,-0.28,-0.29,1,P337R +urn:mavedb:00000044-b-2#268,NA,NA,p.Pro7Arg,-0.3,-0.29,2,P337R +urn:mavedb:00000044-b-2#263,NA,NA,p.Pro7Asn,0.4,0.28,1,P337N +urn:mavedb:00000044-b-2#264,NA,NA,p.Pro7Asn,0.16,0.28,2,P337N +urn:mavedb:00000044-b-2#245,NA,NA,p.Pro7Asp,0.19,0.29,1,P337D +urn:mavedb:00000044-b-2#246,NA,NA,p.Pro7Asp,0.38,0.29,2,P337D +urn:mavedb:00000044-b-2#243,NA,NA,p.Pro7Cys,-0.45,-0.49,1,P337C +urn:mavedb:00000044-b-2#244,NA,NA,p.Pro7Cys,-0.53,-0.49,2,P337C +urn:mavedb:00000044-b-2#265,NA,NA,p.Pro7Gln,-0.11,-0.14,1,P337Q +urn:mavedb:00000044-b-2#266,NA,NA,p.Pro7Gln,-0.17,-0.14,2,P337Q +urn:mavedb:00000044-b-2#247,NA,NA,p.Pro7Glu,0.01,0,1,P337E +urn:mavedb:00000044-b-2#248,NA,NA,p.Pro7Glu,-0.01,0,2,P337E +urn:mavedb:00000044-b-2#251,NA,NA,p.Pro7Gly,-0.3,-0.4,1,P337G +urn:mavedb:00000044-b-2#252,NA,NA,p.Pro7Gly,-0.51,-0.4,2,P337G +urn:mavedb:00000044-b-2#253,NA,NA,p.Pro7His,-0.86,-0.65,1,P337H +urn:mavedb:00000044-b-2#254,NA,NA,p.Pro7His,-0.44,-0.65,2,P337H +urn:mavedb:00000044-b-2#255,NA,NA,p.Pro7Ile,-1.67,-1.57,1,P337I +urn:mavedb:00000044-b-2#256,NA,NA,p.Pro7Ile,-1.47,-1.57,2,P337I +urn:mavedb:00000044-b-2#259,NA,NA,p.Pro7Leu,-0.91,-0.95,1,P337L +urn:mavedb:00000044-b-2#260,NA,NA,p.Pro7Leu,-0.99,-0.95,2,P337L +urn:mavedb:00000044-b-2#257,NA,NA,p.Pro7Lys,-0.45,-0.32,1,P337K +urn:mavedb:00000044-b-2#258,NA,NA,p.Pro7Lys,-0.2,-0.32,2,P337K +urn:mavedb:00000044-b-2#261,NA,NA,p.Pro7Met,-0.77,-0.86,1,P337M +urn:mavedb:00000044-b-2#262,NA,NA,p.Pro7Met,-0.96,-0.86,2,P337M +urn:mavedb:00000044-b-2#249,NA,NA,p.Pro7Phe,-1.06,-1.1,1,P337F +urn:mavedb:00000044-b-2#250,NA,NA,p.Pro7Phe,-1.13,-1.1,2,P337F +urn:mavedb:00000044-b-2#269,NA,NA,p.Pro7Ser,-0.23,-0.23,1,P337S +urn:mavedb:00000044-b-2#270,NA,NA,p.Pro7Ser,-0.23,-0.23,2,P337S +urn:mavedb:00000044-b-2#271,NA,NA,p.Pro7Thr,-0.38,-0.44,1,P337T +urn:mavedb:00000044-b-2#272,NA,NA,p.Pro7Thr,-0.5,-0.44,2,P337T +urn:mavedb:00000044-b-2#275,NA,NA,p.Pro7Trp,-1.22,-1.18,1,P337W +urn:mavedb:00000044-b-2#276,NA,NA,p.Pro7Trp,-1.13,-1.18,2,P337W +urn:mavedb:00000044-b-2#277,NA,NA,p.Pro7Tyr,-1.05,-1.12,1,P337Y +urn:mavedb:00000044-b-2#278,NA,NA,p.Pro7Tyr,-1.18,-1.12,2,P337Y +urn:mavedb:00000044-b-2#273,NA,NA,p.Pro7Val,-1.22,-1.2,1,P337V +urn:mavedb:00000044-b-2#274,NA,NA,p.Pro7Val,-1.19,-1.2,2,P337V +urn:mavedb:00000044-b-2#3279,NA,NA,p.Pro82*,-4.6,-4.58,1,P412 +urn:mavedb:00000044-b-2#3280,NA,NA,p.Pro82*,-4.56,-4.58,2,P412 +urn:mavedb:00000044-b-2#3241,NA,NA,p.Pro82Ala,-2.69,-2.64,1,P412A +urn:mavedb:00000044-b-2#3242,NA,NA,p.Pro82Ala,-2.59,-2.64,2,P412A +urn:mavedb:00000044-b-2#3267,NA,NA,p.Pro82Arg,-2.86,-2.73,1,P412R +urn:mavedb:00000044-b-2#3268,NA,NA,p.Pro82Arg,-2.59,-2.73,2,P412R +urn:mavedb:00000044-b-2#3263,NA,NA,p.Pro82Asn,-2.74,-2.68,1,P412N +urn:mavedb:00000044-b-2#3264,NA,NA,p.Pro82Asn,-2.61,-2.68,2,P412N +urn:mavedb:00000044-b-2#3245,NA,NA,p.Pro82Asp,-2.85,-2.74,1,P412D +urn:mavedb:00000044-b-2#3246,NA,NA,p.Pro82Asp,-2.63,-2.74,2,P412D +urn:mavedb:00000044-b-2#3243,NA,NA,p.Pro82Cys,-2.87,-2.69,1,P412C +urn:mavedb:00000044-b-2#3244,NA,NA,p.Pro82Cys,-2.51,-2.69,2,P412C +urn:mavedb:00000044-b-2#3265,NA,NA,p.Pro82Gln,-2.57,-2.56,1,P412Q +urn:mavedb:00000044-b-2#3266,NA,NA,p.Pro82Gln,-2.55,-2.56,2,P412Q +urn:mavedb:00000044-b-2#3247,NA,NA,p.Pro82Glu,-2.67,-2.55,1,P412E +urn:mavedb:00000044-b-2#3248,NA,NA,p.Pro82Glu,-2.43,-2.55,2,P412E +urn:mavedb:00000044-b-2#3251,NA,NA,p.Pro82Gly,-2.67,-2.63,1,P412G +urn:mavedb:00000044-b-2#3252,NA,NA,p.Pro82Gly,-2.59,-2.63,2,P412G +urn:mavedb:00000044-b-2#3253,NA,NA,p.Pro82His,-2.65,-2.73,1,P412H +urn:mavedb:00000044-b-2#3254,NA,NA,p.Pro82His,-2.8,-2.73,2,P412H +urn:mavedb:00000044-b-2#3255,NA,NA,p.Pro82Ile,-2.92,-2.62,1,P412I +urn:mavedb:00000044-b-2#3256,NA,NA,p.Pro82Ile,-2.33,-2.62,2,P412I +urn:mavedb:00000044-b-2#3259,NA,NA,p.Pro82Leu,-2.65,-2.63,1,P412L +urn:mavedb:00000044-b-2#3260,NA,NA,p.Pro82Leu,-2.61,-2.63,2,P412L +urn:mavedb:00000044-b-2#3257,NA,NA,p.Pro82Lys,-2.56,-2.5,1,P412K +urn:mavedb:00000044-b-2#3258,NA,NA,p.Pro82Lys,-2.44,-2.5,2,P412K +urn:mavedb:00000044-b-2#3261,NA,NA,p.Pro82Met,-2.92,-2.79,1,P412M +urn:mavedb:00000044-b-2#3262,NA,NA,p.Pro82Met,-2.66,-2.79,2,P412M +urn:mavedb:00000044-b-2#3249,NA,NA,p.Pro82Phe,-2.89,-2.86,1,P412F +urn:mavedb:00000044-b-2#3250,NA,NA,p.Pro82Phe,-2.83,-2.86,2,P412F +urn:mavedb:00000044-b-2#3269,NA,NA,p.Pro82Ser,-2.6,-2.58,1,P412S +urn:mavedb:00000044-b-2#3270,NA,NA,p.Pro82Ser,-2.56,-2.58,2,P412S +urn:mavedb:00000044-b-2#3271,NA,NA,p.Pro82Thr,-2.52,-2.49,1,P412T +urn:mavedb:00000044-b-2#3272,NA,NA,p.Pro82Thr,-2.45,-2.49,2,P412T +urn:mavedb:00000044-b-2#3275,NA,NA,p.Pro82Trp,-2.86,-2.78,1,P412W +urn:mavedb:00000044-b-2#3276,NA,NA,p.Pro82Trp,-2.71,-2.78,2,P412W +urn:mavedb:00000044-b-2#3277,NA,NA,p.Pro82Tyr,-2.94,-2.87,1,P412Y +urn:mavedb:00000044-b-2#3278,NA,NA,p.Pro82Tyr,-2.81,-2.87,2,P412Y +urn:mavedb:00000044-b-2#3273,NA,NA,p.Pro82Val,-2.37,-2.36,1,P412V +urn:mavedb:00000044-b-2#3274,NA,NA,p.Pro82Val,-2.35,-2.36,2,P412V +urn:mavedb:00000044-b-2#3839,NA,NA,p.Pro96*,-4.6,-4.56,1,P426 +urn:mavedb:00000044-b-2#3840,NA,NA,p.Pro96*,-4.53,-4.56,2,P426 +urn:mavedb:00000044-b-2#3801,NA,NA,p.Pro96Ala,-1.41,-1.61,1,P426A +urn:mavedb:00000044-b-2#3802,NA,NA,p.Pro96Ala,-1.81,-1.61,2,P426A +urn:mavedb:00000044-b-2#3827,NA,NA,p.Pro96Arg,-2.37,-2.33,1,P426R +urn:mavedb:00000044-b-2#3828,NA,NA,p.Pro96Arg,-2.29,-2.33,2,P426R +urn:mavedb:00000044-b-2#3823,NA,NA,p.Pro96Asn,-1.55,-1.46,1,P426N +urn:mavedb:00000044-b-2#3824,NA,NA,p.Pro96Asn,-1.37,-1.46,2,P426N +urn:mavedb:00000044-b-2#3805,NA,NA,p.Pro96Asp,-1.99,-1.89,1,P426D +urn:mavedb:00000044-b-2#3806,NA,NA,p.Pro96Asp,-1.78,-1.89,2,P426D +urn:mavedb:00000044-b-2#3803,NA,NA,p.Pro96Cys,-2.45,-2.34,1,P426C +urn:mavedb:00000044-b-2#3804,NA,NA,p.Pro96Cys,-2.23,-2.34,2,P426C +urn:mavedb:00000044-b-2#3825,NA,NA,p.Pro96Gln,-2.44,-2.36,1,P426Q +urn:mavedb:00000044-b-2#3826,NA,NA,p.Pro96Gln,-2.28,-2.36,2,P426Q +urn:mavedb:00000044-b-2#3807,NA,NA,p.Pro96Glu,-2.29,-2.31,1,P426E +urn:mavedb:00000044-b-2#3808,NA,NA,p.Pro96Glu,-2.32,-2.31,2,P426E +urn:mavedb:00000044-b-2#3811,NA,NA,p.Pro96Gly,-1.18,-1.29,1,P426G +urn:mavedb:00000044-b-2#3812,NA,NA,p.Pro96Gly,-1.4,-1.29,2,P426G +urn:mavedb:00000044-b-2#3813,NA,NA,p.Pro96His,-2.42,-2.33,1,P426H +urn:mavedb:00000044-b-2#3814,NA,NA,p.Pro96His,-2.25,-2.33,2,P426H +urn:mavedb:00000044-b-2#3815,NA,NA,p.Pro96Ile,-2.92,-2.84,1,P426I +urn:mavedb:00000044-b-2#3816,NA,NA,p.Pro96Ile,-2.77,-2.84,2,P426I +urn:mavedb:00000044-b-2#3819,NA,NA,p.Pro96Leu,-2.95,-2.87,1,P426L +urn:mavedb:00000044-b-2#3820,NA,NA,p.Pro96Leu,-2.8,-2.87,2,P426L +urn:mavedb:00000044-b-2#3817,NA,NA,p.Pro96Lys,-2.12,-2.07,1,P426K +urn:mavedb:00000044-b-2#3818,NA,NA,p.Pro96Lys,-2.02,-2.07,2,P426K +urn:mavedb:00000044-b-2#3821,NA,NA,p.Pro96Met,-2.93,-2.87,1,P426M +urn:mavedb:00000044-b-2#3822,NA,NA,p.Pro96Met,-2.82,-2.87,2,P426M +urn:mavedb:00000044-b-2#3809,NA,NA,p.Pro96Phe,-3,-2.9,1,P426F +urn:mavedb:00000044-b-2#3810,NA,NA,p.Pro96Phe,-2.8,-2.9,2,P426F +urn:mavedb:00000044-b-2#3829,NA,NA,p.Pro96Ser,-1.36,-1.43,1,P426S +urn:mavedb:00000044-b-2#3830,NA,NA,p.Pro96Ser,-1.51,-1.43,2,P426S +urn:mavedb:00000044-b-2#3831,NA,NA,p.Pro96Thr,-1.95,-1.95,1,P426T +urn:mavedb:00000044-b-2#3832,NA,NA,p.Pro96Thr,-1.96,-1.95,2,P426T +urn:mavedb:00000044-b-2#3835,NA,NA,p.Pro96Trp,-2.92,-2.89,1,P426W +urn:mavedb:00000044-b-2#3836,NA,NA,p.Pro96Trp,-2.86,-2.89,2,P426W +urn:mavedb:00000044-b-2#3837,NA,NA,p.Pro96Tyr,-2.95,-2.87,1,P426Y +urn:mavedb:00000044-b-2#3838,NA,NA,p.Pro96Tyr,-2.79,-2.87,2,P426Y +urn:mavedb:00000044-b-2#3833,NA,NA,p.Pro96Val,-2.67,-2.73,1,P426V +urn:mavedb:00000044-b-2#3834,NA,NA,p.Pro96Val,-2.78,-2.73,2,P426V +urn:mavedb:00000044-b-2#4319,NA,NA,p.Ser108*,-4.57,-4.36,1,S438 +urn:mavedb:00000044-b-2#4320,NA,NA,p.Ser108*,-4.16,-4.36,2,S438 +urn:mavedb:00000044-b-2#4281,NA,NA,p.Ser108Ala,-0.34,-0.24,1,S438A +urn:mavedb:00000044-b-2#4282,NA,NA,p.Ser108Ala,-0.15,-0.24,2,S438A +urn:mavedb:00000044-b-2#4309,NA,NA,p.Ser108Arg,-2.9,-2.81,1,S438R +urn:mavedb:00000044-b-2#4310,NA,NA,p.Ser108Arg,-2.72,-2.81,2,S438R +urn:mavedb:00000044-b-2#4303,NA,NA,p.Ser108Asn,-1.96,-2.37,1,S438N +urn:mavedb:00000044-b-2#4304,NA,NA,p.Ser108Asn,-2.79,-2.37,2,S438N +urn:mavedb:00000044-b-2#4285,NA,NA,p.Ser108Asp,-1.39,-2.08,1,S438D +urn:mavedb:00000044-b-2#4286,NA,NA,p.Ser108Asp,-2.77,-2.08,2,S438D +urn:mavedb:00000044-b-2#4283,NA,NA,p.Ser108Cys,-1.6,-1.62,1,S438C +urn:mavedb:00000044-b-2#4284,NA,NA,p.Ser108Cys,-1.64,-1.62,2,S438C +urn:mavedb:00000044-b-2#4307,NA,NA,p.Ser108Gln,-1.56,-2.26,1,S438Q +urn:mavedb:00000044-b-2#4308,NA,NA,p.Ser108Gln,-2.97,-2.26,2,S438Q +urn:mavedb:00000044-b-2#4287,NA,NA,p.Ser108Glu,-1.15,-1.53,1,S438E +urn:mavedb:00000044-b-2#4288,NA,NA,p.Ser108Glu,-1.9,-1.53,2,S438E +urn:mavedb:00000044-b-2#4291,NA,NA,p.Ser108Gly,-2.08,-1.21,1,S438G +urn:mavedb:00000044-b-2#4292,NA,NA,p.Ser108Gly,-0.35,-1.21,2,S438G 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+urn:mavedb:00000044-b-2#1776,NA,NA,p.Ser45Ile,-1.94,-1.99,2,S375I +urn:mavedb:00000044-b-2#1779,NA,NA,p.Ser45Leu,-1.68,-1.62,1,S375L +urn:mavedb:00000044-b-2#1780,NA,NA,p.Ser45Leu,-1.57,-1.62,2,S375L +urn:mavedb:00000044-b-2#1777,NA,NA,p.Ser45Lys,-1.11,-0.98,1,S375K +urn:mavedb:00000044-b-2#1778,NA,NA,p.Ser45Lys,-0.86,-0.98,2,S375K +urn:mavedb:00000044-b-2#1781,NA,NA,p.Ser45Met,-1.34,-1.24,1,S375M +urn:mavedb:00000044-b-2#1782,NA,NA,p.Ser45Met,-1.14,-1.24,2,S375M +urn:mavedb:00000044-b-2#1769,NA,NA,p.Ser45Phe,-1.83,-1.81,1,S375F +urn:mavedb:00000044-b-2#1770,NA,NA,p.Ser45Phe,-1.79,-1.81,2,S375F +urn:mavedb:00000044-b-2#1785,NA,NA,p.Ser45Pro,-0.97,-1.1,1,S375P +urn:mavedb:00000044-b-2#1786,NA,NA,p.Ser45Pro,-1.23,-1.1,2,S375P +urn:mavedb:00000044-b-2#1791,NA,NA,p.Ser45Thr,-0.27,-0.24,1,S375T +urn:mavedb:00000044-b-2#1792,NA,NA,p.Ser45Thr,-0.21,-0.24,2,S375T +urn:mavedb:00000044-b-2#1795,NA,NA,p.Ser45Trp,-1.66,-1.56,1,S375W 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+urn:mavedb:00000044-b-2#3962,NA,NA,p.Thr100Ala,-0.93,-0.91,2,T430A +urn:mavedb:00000044-b-2#3989,NA,NA,p.Thr100Arg,-0.12,-0.14,1,T430R +urn:mavedb:00000044-b-2#3990,NA,NA,p.Thr100Arg,-0.16,-0.14,2,T430R +urn:mavedb:00000044-b-2#3983,NA,NA,p.Thr100Asn,-0.96,-0.87,1,T430N +urn:mavedb:00000044-b-2#3984,NA,NA,p.Thr100Asn,-0.78,-0.87,2,T430N +urn:mavedb:00000044-b-2#3965,NA,NA,p.Thr100Asp,-1.99,-1.97,1,T430D +urn:mavedb:00000044-b-2#3966,NA,NA,p.Thr100Asp,-1.95,-1.97,2,T430D +urn:mavedb:00000044-b-2#3963,NA,NA,p.Thr100Cys,-0.05,-0.06,1,T430C +urn:mavedb:00000044-b-2#3964,NA,NA,p.Thr100Cys,-0.07,-0.06,2,T430C +urn:mavedb:00000044-b-2#3987,NA,NA,p.Thr100Gln,-0.29,-0.38,1,T430Q +urn:mavedb:00000044-b-2#3988,NA,NA,p.Thr100Gln,-0.47,-0.38,2,T430Q +urn:mavedb:00000044-b-2#3967,NA,NA,p.Thr100Glu,-1.1,-1.19,1,T430E +urn:mavedb:00000044-b-2#3968,NA,NA,p.Thr100Glu,-1.29,-1.19,2,T430E +urn:mavedb:00000044-b-2#3971,NA,NA,p.Thr100Gly,-2.24,-2.25,1,T430G +urn:mavedb:00000044-b-2#3972,NA,NA,p.Thr100Gly,-2.25,-2.25,2,T430G +urn:mavedb:00000044-b-2#3973,NA,NA,p.Thr100His,-0.39,-0.35,1,T430H +urn:mavedb:00000044-b-2#3974,NA,NA,p.Thr100His,-0.31,-0.35,2,T430H +urn:mavedb:00000044-b-2#3975,NA,NA,p.Thr100Ile,0.14,0.07,1,T430I +urn:mavedb:00000044-b-2#3976,NA,NA,p.Thr100Ile,0,0.07,2,T430I +urn:mavedb:00000044-b-2#3979,NA,NA,p.Thr100Leu,-0.04,-0.03,1,T430L +urn:mavedb:00000044-b-2#3980,NA,NA,p.Thr100Leu,-0.03,-0.03,2,T430L +urn:mavedb:00000044-b-2#3977,NA,NA,p.Thr100Lys,-0.34,-0.21,1,T430K +urn:mavedb:00000044-b-2#3978,NA,NA,p.Thr100Lys,-0.07,-0.21,2,T430K +urn:mavedb:00000044-b-2#3981,NA,NA,p.Thr100Met,-0.01,-0.01,1,T430M +urn:mavedb:00000044-b-2#3982,NA,NA,p.Thr100Met,-0.02,-0.01,2,T430M +urn:mavedb:00000044-b-2#3969,NA,NA,p.Thr100Phe,-0.03,0.02,1,T430F +urn:mavedb:00000044-b-2#3970,NA,NA,p.Thr100Phe,0.07,0.02,2,T430F +urn:mavedb:00000044-b-2#3985,NA,NA,p.Thr100Pro,-2.9,-2.86,1,T430P +urn:mavedb:00000044-b-2#3986,NA,NA,p.Thr100Pro,-2.83,-2.86,2,T430P +urn:mavedb:00000044-b-2#3991,NA,NA,p.Thr100Ser,-1.11,-0.97,1,T430S +urn:mavedb:00000044-b-2#3992,NA,NA,p.Thr100Ser,-0.84,-0.97,2,T430S +urn:mavedb:00000044-b-2#3995,NA,NA,p.Thr100Trp,-0.76,-0.82,1,T430W +urn:mavedb:00000044-b-2#3996,NA,NA,p.Thr100Trp,-0.88,-0.82,2,T430W +urn:mavedb:00000044-b-2#3997,NA,NA,p.Thr100Tyr,-0.07,-0.06,1,T430Y +urn:mavedb:00000044-b-2#3998,NA,NA,p.Thr100Tyr,-0.05,-0.06,2,T430Y +urn:mavedb:00000044-b-2#3993,NA,NA,p.Thr100Val,0.22,0.16,1,T430V +urn:mavedb:00000044-b-2#3994,NA,NA,p.Thr100Val,0.1,0.16,2,T430V +urn:mavedb:00000044-b-2#5599,NA,NA,p.Thr140*,-4.61,-4.57,1,T470 +urn:mavedb:00000044-b-2#5600,NA,NA,p.Thr140*,-4.52,-4.57,2,T470 +urn:mavedb:00000044-b-2#5561,NA,NA,p.Thr140Ala,-0.23,-0.25,1,T470A +urn:mavedb:00000044-b-2#5562,NA,NA,p.Thr140Ala,-0.26,-0.25,2,T470A +urn:mavedb:00000044-b-2#5589,NA,NA,p.Thr140Arg,-0.2,-0.17,1,T470R +urn:mavedb:00000044-b-2#5590,NA,NA,p.Thr140Arg,-0.14,-0.17,2,T470R +urn:mavedb:00000044-b-2#5583,NA,NA,p.Thr140Asn,-0.18,-0.18,1,T470N +urn:mavedb:00000044-b-2#5584,NA,NA,p.Thr140Asn,-0.18,-0.18,2,T470N +urn:mavedb:00000044-b-2#5565,NA,NA,p.Thr140Asp,-0.23,-0.27,1,T470D +urn:mavedb:00000044-b-2#5566,NA,NA,p.Thr140Asp,-0.31,-0.27,2,T470D +urn:mavedb:00000044-b-2#5563,NA,NA,p.Thr140Cys,-0.19,-0.22,1,T470C +urn:mavedb:00000044-b-2#5564,NA,NA,p.Thr140Cys,-0.26,-0.22,2,T470C +urn:mavedb:00000044-b-2#5587,NA,NA,p.Thr140Gln,-0.11,-0.08,1,T470Q +urn:mavedb:00000044-b-2#5588,NA,NA,p.Thr140Gln,-0.04,-0.08,2,T470Q +urn:mavedb:00000044-b-2#5567,NA,NA,p.Thr140Glu,-0.06,-0.07,1,T470E +urn:mavedb:00000044-b-2#5568,NA,NA,p.Thr140Glu,-0.08,-0.07,2,T470E +urn:mavedb:00000044-b-2#5571,NA,NA,p.Thr140Gly,-0.43,-0.51,1,T470G +urn:mavedb:00000044-b-2#5572,NA,NA,p.Thr140Gly,-0.58,-0.51,2,T470G +urn:mavedb:00000044-b-2#5573,NA,NA,p.Thr140His,-0.19,-0.31,1,T470H +urn:mavedb:00000044-b-2#5574,NA,NA,p.Thr140His,-0.43,-0.31,2,T470H +urn:mavedb:00000044-b-2#5575,NA,NA,p.Thr140Ile,-0.35,-0.47,1,T470I +urn:mavedb:00000044-b-2#5576,NA,NA,p.Thr140Ile,-0.59,-0.47,2,T470I +urn:mavedb:00000044-b-2#5579,NA,NA,p.Thr140Leu,-0.31,-0.35,1,T470L +urn:mavedb:00000044-b-2#5580,NA,NA,p.Thr140Leu,-0.38,-0.35,2,T470L +urn:mavedb:00000044-b-2#5577,NA,NA,p.Thr140Lys,-0.23,-0.2,1,T470K +urn:mavedb:00000044-b-2#5578,NA,NA,p.Thr140Lys,-0.17,-0.2,2,T470K +urn:mavedb:00000044-b-2#5581,NA,NA,p.Thr140Met,-0.27,-0.25,1,T470M +urn:mavedb:00000044-b-2#5582,NA,NA,p.Thr140Met,-0.24,-0.25,2,T470M +urn:mavedb:00000044-b-2#5569,NA,NA,p.Thr140Phe,-0.88,-0.92,1,T470F +urn:mavedb:00000044-b-2#5570,NA,NA,p.Thr140Phe,-0.97,-0.92,2,T470F +urn:mavedb:00000044-b-2#5585,NA,NA,p.Thr140Pro,-1.07,-1.09,1,T470P +urn:mavedb:00000044-b-2#5586,NA,NA,p.Thr140Pro,-1.11,-1.09,2,T470P +urn:mavedb:00000044-b-2#5591,NA,NA,p.Thr140Ser,-0.19,-0.2,1,T470S +urn:mavedb:00000044-b-2#5592,NA,NA,p.Thr140Ser,-0.2,-0.2,2,T470S +urn:mavedb:00000044-b-2#5595,NA,NA,p.Thr140Trp,-0.65,-1.05,1,T470W +urn:mavedb:00000044-b-2#5596,NA,NA,p.Thr140Trp,-1.45,-1.05,2,T470W +urn:mavedb:00000044-b-2#5597,NA,NA,p.Thr140Tyr,-0.46,-0.53,1,T470Y +urn:mavedb:00000044-b-2#5598,NA,NA,p.Thr140Tyr,-0.61,-0.53,2,T470Y +urn:mavedb:00000044-b-2#5593,NA,NA,p.Thr140Val,-0.21,-0.33,1,T470V +urn:mavedb:00000044-b-2#5594,NA,NA,p.Thr140Val,-0.44,-0.33,2,T470V +urn:mavedb:00000044-b-2#5919,NA,NA,p.Thr148*,-4.59,-4.57,1,T478 +urn:mavedb:00000044-b-2#5920,NA,NA,p.Thr148*,-4.54,-4.57,2,T478 +urn:mavedb:00000044-b-2#5881,NA,NA,p.Thr148Ala,-0.09,-0.11,1,T478A +urn:mavedb:00000044-b-2#5882,NA,NA,p.Thr148Ala,-0.13,-0.11,2,T478A +urn:mavedb:00000044-b-2#5909,NA,NA,p.Thr148Arg,-0.16,-0.09,1,T478R +urn:mavedb:00000044-b-2#5910,NA,NA,p.Thr148Arg,-0.02,-0.09,2,T478R +urn:mavedb:00000044-b-2#5903,NA,NA,p.Thr148Asn,-0.17,-0.26,1,T478N +urn:mavedb:00000044-b-2#5904,NA,NA,p.Thr148Asn,-0.35,-0.26,2,T478N +urn:mavedb:00000044-b-2#5885,NA,NA,p.Thr148Asp,-0.05,-0.17,1,T478D +urn:mavedb:00000044-b-2#5886,NA,NA,p.Thr148Asp,-0.29,-0.17,2,T478D +urn:mavedb:00000044-b-2#5883,NA,NA,p.Thr148Cys,-0.31,-0.28,1,T478C +urn:mavedb:00000044-b-2#5884,NA,NA,p.Thr148Cys,-0.25,-0.28,2,T478C +urn:mavedb:00000044-b-2#5907,NA,NA,p.Thr148Gln,-0.1,-0.04,1,T478Q +urn:mavedb:00000044-b-2#5908,NA,NA,p.Thr148Gln,0.01,-0.04,2,T478Q +urn:mavedb:00000044-b-2#5887,NA,NA,p.Thr148Glu,-0.08,-0.04,1,T478E +urn:mavedb:00000044-b-2#5888,NA,NA,p.Thr148Glu,0,-0.04,2,T478E +urn:mavedb:00000044-b-2#5891,NA,NA,p.Thr148Gly,-0.3,-0.32,1,T478G +urn:mavedb:00000044-b-2#5892,NA,NA,p.Thr148Gly,-0.34,-0.32,2,T478G +urn:mavedb:00000044-b-2#5893,NA,NA,p.Thr148His,-0.21,-0.22,1,T478H +urn:mavedb:00000044-b-2#5894,NA,NA,p.Thr148His,-0.22,-0.22,2,T478H +urn:mavedb:00000044-b-2#5895,NA,NA,p.Thr148Ile,-0.14,-0.16,1,T478I +urn:mavedb:00000044-b-2#5896,NA,NA,p.Thr148Ile,-0.18,-0.16,2,T478I +urn:mavedb:00000044-b-2#5899,NA,NA,p.Thr148Leu,-0.17,-0.2,1,T478L +urn:mavedb:00000044-b-2#5900,NA,NA,p.Thr148Leu,-0.24,-0.2,2,T478L +urn:mavedb:00000044-b-2#5897,NA,NA,p.Thr148Lys,-0.03,0.02,1,T478K +urn:mavedb:00000044-b-2#5898,NA,NA,p.Thr148Lys,0.08,0.02,2,T478K +urn:mavedb:00000044-b-2#5901,NA,NA,p.Thr148Met,-0.27,-0.3,1,T478M +urn:mavedb:00000044-b-2#5902,NA,NA,p.Thr148Met,-0.32,-0.3,2,T478M +urn:mavedb:00000044-b-2#5889,NA,NA,p.Thr148Phe,-0.23,-0.26,1,T478F +urn:mavedb:00000044-b-2#5890,NA,NA,p.Thr148Phe,-0.29,-0.26,2,T478F +urn:mavedb:00000044-b-2#5905,NA,NA,p.Thr148Pro,-0.53,-0.63,1,T478P +urn:mavedb:00000044-b-2#5906,NA,NA,p.Thr148Pro,-0.72,-0.63,2,T478P +urn:mavedb:00000044-b-2#5911,NA,NA,p.Thr148Ser,-0.05,-0.09,1,T478S +urn:mavedb:00000044-b-2#5912,NA,NA,p.Thr148Ser,-0.14,-0.09,2,T478S +urn:mavedb:00000044-b-2#5915,NA,NA,p.Thr148Trp,-0.36,-0.56,1,T478W +urn:mavedb:00000044-b-2#5916,NA,NA,p.Thr148Trp,-0.75,-0.56,2,T478W +urn:mavedb:00000044-b-2#5917,NA,NA,p.Thr148Tyr,-0.32,-0.31,1,T478Y +urn:mavedb:00000044-b-2#5918,NA,NA,p.Thr148Tyr,-0.3,-0.31,2,T478Y +urn:mavedb:00000044-b-2#5913,NA,NA,p.Thr148Val,-0.22,-0.2,1,T478V +urn:mavedb:00000044-b-2#5914,NA,NA,p.Thr148Val,-0.19,-0.2,2,T478V +urn:mavedb:00000044-b-2#599,NA,NA,p.Thr15*,-4.59,-4.59,1,T345 +urn:mavedb:00000044-b-2#600,NA,NA,p.Thr15*,-4.58,-4.59,2,T345 +urn:mavedb:00000044-b-2#561,NA,NA,p.Thr15Ala,-0.92,-0.98,1,T345A +urn:mavedb:00000044-b-2#562,NA,NA,p.Thr15Ala,-1.04,-0.98,2,T345A +urn:mavedb:00000044-b-2#589,NA,NA,p.Thr15Arg,-0.78,-1,1,T345R +urn:mavedb:00000044-b-2#590,NA,NA,p.Thr15Arg,-1.22,-1,2,T345R +urn:mavedb:00000044-b-2#583,NA,NA,p.Thr15Asn,-1.74,-1.65,1,T345N +urn:mavedb:00000044-b-2#584,NA,NA,p.Thr15Asn,-1.57,-1.65,2,T345N +urn:mavedb:00000044-b-2#565,NA,NA,p.Thr15Asp,-0.66,-0.66,1,T345D +urn:mavedb:00000044-b-2#566,NA,NA,p.Thr15Asp,-0.66,-0.66,2,T345D +urn:mavedb:00000044-b-2#563,NA,NA,p.Thr15Cys,-2.11,-2.2,1,T345C +urn:mavedb:00000044-b-2#564,NA,NA,p.Thr15Cys,-2.29,-2.2,2,T345C +urn:mavedb:00000044-b-2#587,NA,NA,p.Thr15Gln,-3.06,-1.91,1,T345Q +urn:mavedb:00000044-b-2#588,NA,NA,p.Thr15Gln,-0.77,-1.91,2,T345Q +urn:mavedb:00000044-b-2#567,NA,NA,p.Thr15Glu,-0.52,-0.51,1,T345E +urn:mavedb:00000044-b-2#568,NA,NA,p.Thr15Glu,-0.49,-0.51,2,T345E +urn:mavedb:00000044-b-2#571,NA,NA,p.Thr15Gly,-1.9,-1.8,1,T345G +urn:mavedb:00000044-b-2#572,NA,NA,p.Thr15Gly,-1.69,-1.8,2,T345G +urn:mavedb:00000044-b-2#573,NA,NA,p.Thr15His,-0.96,-2.01,1,T345H +urn:mavedb:00000044-b-2#574,NA,NA,p.Thr15His,-3.06,-2.01,2,T345H +urn:mavedb:00000044-b-2#575,NA,NA,p.Thr15Ile,-2.05,-1.91,1,T345I +urn:mavedb:00000044-b-2#576,NA,NA,p.Thr15Ile,-1.77,-1.91,2,T345I +urn:mavedb:00000044-b-2#579,NA,NA,p.Thr15Leu,-1.17,-1.23,1,T345L +urn:mavedb:00000044-b-2#580,NA,NA,p.Thr15Leu,-1.3,-1.23,2,T345L +urn:mavedb:00000044-b-2#577,NA,NA,p.Thr15Lys,-0.39,-0.59,1,T345K +urn:mavedb:00000044-b-2#578,NA,NA,p.Thr15Lys,-0.79,-0.59,2,T345K +urn:mavedb:00000044-b-2#581,NA,NA,p.Thr15Met,-1.77,-1.84,1,T345M +urn:mavedb:00000044-b-2#582,NA,NA,p.Thr15Met,-1.91,-1.84,2,T345M +urn:mavedb:00000044-b-2#569,NA,NA,p.Thr15Phe,-3.03,-3.01,1,T345F +urn:mavedb:00000044-b-2#570,NA,NA,p.Thr15Phe,-2.99,-3.01,2,T345F +urn:mavedb:00000044-b-2#585,NA,NA,p.Thr15Pro,-0.29,-0.34,1,T345P +urn:mavedb:00000044-b-2#586,NA,NA,p.Thr15Pro,-0.39,-0.34,2,T345P +urn:mavedb:00000044-b-2#591,NA,NA,p.Thr15Ser,-0.16,-0.16,1,T345S +urn:mavedb:00000044-b-2#592,NA,NA,p.Thr15Ser,-0.17,-0.16,2,T345S +urn:mavedb:00000044-b-2#595,NA,NA,p.Thr15Trp,-2.27,-2.7,1,T345W +urn:mavedb:00000044-b-2#596,NA,NA,p.Thr15Trp,-3.13,-2.7,2,T345W +urn:mavedb:00000044-b-2#597,NA,NA,p.Thr15Tyr,-3.18,-2.47,1,T345Y +urn:mavedb:00000044-b-2#598,NA,NA,p.Thr15Tyr,-1.77,-2.47,2,T345Y +urn:mavedb:00000044-b-2#593,NA,NA,p.Thr15Val,-1.27,-1.31,1,T345V +urn:mavedb:00000044-b-2#594,NA,NA,p.Thr15Val,-1.34,-1.31,2,T345V +urn:mavedb:00000044-b-2#6799,NA,NA,p.Thr170*,-4.54,-4.5,1,T500 +urn:mavedb:00000044-b-2#6800,NA,NA,p.Thr170*,-4.47,-4.5,2,T500 +urn:mavedb:00000044-b-2#6761,NA,NA,p.Thr170Ala,0,-0.02,1,T500A +urn:mavedb:00000044-b-2#6762,NA,NA,p.Thr170Ala,-0.04,-0.02,2,T500A +urn:mavedb:00000044-b-2#6789,NA,NA,p.Thr170Arg,-0.36,-0.34,1,T500R +urn:mavedb:00000044-b-2#6790,NA,NA,p.Thr170Arg,-0.32,-0.34,2,T500R +urn:mavedb:00000044-b-2#6783,NA,NA,p.Thr170Asn,0.02,-0.04,1,T500N +urn:mavedb:00000044-b-2#6784,NA,NA,p.Thr170Asn,-0.1,-0.04,2,T500N +urn:mavedb:00000044-b-2#6765,NA,NA,p.Thr170Asp,0.11,-0.01,1,T500D +urn:mavedb:00000044-b-2#6766,NA,NA,p.Thr170Asp,-0.12,-0.01,2,T500D +urn:mavedb:00000044-b-2#6763,NA,NA,p.Thr170Cys,-0.41,-0.33,1,T500C +urn:mavedb:00000044-b-2#6764,NA,NA,p.Thr170Cys,-0.24,-0.33,2,T500C +urn:mavedb:00000044-b-2#6787,NA,NA,p.Thr170Gln,-0.08,-0.02,1,T500Q +urn:mavedb:00000044-b-2#6788,NA,NA,p.Thr170Gln,0.05,-0.02,2,T500Q +urn:mavedb:00000044-b-2#6767,NA,NA,p.Thr170Glu,-0.02,0.01,1,T500E +urn:mavedb:00000044-b-2#6768,NA,NA,p.Thr170Glu,0.03,0.01,2,T500E +urn:mavedb:00000044-b-2#6771,NA,NA,p.Thr170Gly,0.01,0.06,1,T500G +urn:mavedb:00000044-b-2#6772,NA,NA,p.Thr170Gly,0.11,0.06,2,T500G +urn:mavedb:00000044-b-2#6773,NA,NA,p.Thr170His,-0.02,-0.19,1,T500H +urn:mavedb:00000044-b-2#6774,NA,NA,p.Thr170His,-0.35,-0.19,2,T500H +urn:mavedb:00000044-b-2#6775,NA,NA,p.Thr170Ile,-0.48,-0.48,1,T500I +urn:mavedb:00000044-b-2#6776,NA,NA,p.Thr170Ile,-0.48,-0.48,2,T500I +urn:mavedb:00000044-b-2#6779,NA,NA,p.Thr170Leu,-0.25,-0.29,1,T500L +urn:mavedb:00000044-b-2#6780,NA,NA,p.Thr170Leu,-0.34,-0.29,2,T500L +urn:mavedb:00000044-b-2#6777,NA,NA,p.Thr170Lys,-0.06,-0.11,1,T500K +urn:mavedb:00000044-b-2#6778,NA,NA,p.Thr170Lys,-0.17,-0.11,2,T500K +urn:mavedb:00000044-b-2#6781,NA,NA,p.Thr170Met,-0.16,-0.31,1,T500M +urn:mavedb:00000044-b-2#6782,NA,NA,p.Thr170Met,-0.46,-0.31,2,T500M +urn:mavedb:00000044-b-2#6769,NA,NA,p.Thr170Phe,-0.28,-0.26,1,T500F +urn:mavedb:00000044-b-2#6770,NA,NA,p.Thr170Phe,-0.25,-0.26,2,T500F +urn:mavedb:00000044-b-2#6785,NA,NA,p.Thr170Pro,-0.61,-0.98,1,T500P +urn:mavedb:00000044-b-2#6786,NA,NA,p.Thr170Pro,-1.34,-0.98,2,T500P +urn:mavedb:00000044-b-2#6791,NA,NA,p.Thr170Ser,0.01,0,1,T500S +urn:mavedb:00000044-b-2#6792,NA,NA,p.Thr170Ser,-0.01,0,2,T500S +urn:mavedb:00000044-b-2#6795,NA,NA,p.Thr170Trp,-0.42,-0.42,1,T500W +urn:mavedb:00000044-b-2#6796,NA,NA,p.Thr170Trp,-0.42,-0.42,2,T500W +urn:mavedb:00000044-b-2#6797,NA,NA,p.Thr170Tyr,-0.21,-0.28,1,T500Y +urn:mavedb:00000044-b-2#6798,NA,NA,p.Thr170Tyr,-0.35,-0.28,2,T500Y +urn:mavedb:00000044-b-2#6793,NA,NA,p.Thr170Val,-0.45,-0.42,1,T500V +urn:mavedb:00000044-b-2#6794,NA,NA,p.Thr170Val,-0.39,-0.42,2,T500V +urn:mavedb:00000044-b-2#7719,NA,NA,p.Thr193*,NA,NA,1,T523 +urn:mavedb:00000044-b-2#7720,NA,NA,p.Thr193*,NA,NA,2,T523 +urn:mavedb:00000044-b-2#7681,NA,NA,p.Thr193Ala,-0.15,-0.4,1,T523A +urn:mavedb:00000044-b-2#7682,NA,NA,p.Thr193Ala,-0.65,-0.4,2,T523A +urn:mavedb:00000044-b-2#7709,NA,NA,p.Thr193Arg,-0.34,-1.31,1,T523R +urn:mavedb:00000044-b-2#7710,NA,NA,p.Thr193Arg,-2.27,-1.31,2,T523R +urn:mavedb:00000044-b-2#7703,NA,NA,p.Thr193Asn,-0.7,-0.27,1,T523N +urn:mavedb:00000044-b-2#7704,NA,NA,p.Thr193Asn,0.17,-0.27,2,T523N +urn:mavedb:00000044-b-2#7685,NA,NA,p.Thr193Asp,NA,-2.19,1,T523D +urn:mavedb:00000044-b-2#7686,NA,NA,p.Thr193Asp,-2.19,-2.19,2,T523D +urn:mavedb:00000044-b-2#7683,NA,NA,p.Thr193Cys,NA,NA,1,T523C +urn:mavedb:00000044-b-2#7684,NA,NA,p.Thr193Cys,NA,NA,2,T523C +urn:mavedb:00000044-b-2#7707,NA,NA,p.Thr193Gln,-2.88,-2.88,1,T523Q +urn:mavedb:00000044-b-2#7708,NA,NA,p.Thr193Gln,NA,-2.88,2,T523Q +urn:mavedb:00000044-b-2#7687,NA,NA,p.Thr193Glu,NA,NA,1,T523E +urn:mavedb:00000044-b-2#7688,NA,NA,p.Thr193Glu,NA,NA,2,T523E +urn:mavedb:00000044-b-2#7691,NA,NA,p.Thr193Gly,NA,-2.9,1,T523G +urn:mavedb:00000044-b-2#7692,NA,NA,p.Thr193Gly,-2.9,-2.9,2,T523G +urn:mavedb:00000044-b-2#7693,NA,NA,p.Thr193His,-2.96,-2.96,1,T523H +urn:mavedb:00000044-b-2#7694,NA,NA,p.Thr193His,NA,-2.96,2,T523H +urn:mavedb:00000044-b-2#7695,NA,NA,p.Thr193Ile,-0.31,-0.55,1,T523I +urn:mavedb:00000044-b-2#7696,NA,NA,p.Thr193Ile,-0.79,-0.55,2,T523I +urn:mavedb:00000044-b-2#7699,NA,NA,p.Thr193Leu,NA,NA,1,T523L +urn:mavedb:00000044-b-2#7700,NA,NA,p.Thr193Leu,NA,NA,2,T523L +urn:mavedb:00000044-b-2#7697,NA,NA,p.Thr193Lys,-2.95,-2.95,1,T523K +urn:mavedb:00000044-b-2#7698,NA,NA,p.Thr193Lys,NA,-2.95,2,T523K +urn:mavedb:00000044-b-2#7701,NA,NA,p.Thr193Met,-2.87,-2.87,1,T523M +urn:mavedb:00000044-b-2#7702,NA,NA,p.Thr193Met,NA,-2.87,2,T523M +urn:mavedb:00000044-b-2#7689,NA,NA,p.Thr193Phe,NA,-0.3,1,T523F +urn:mavedb:00000044-b-2#7690,NA,NA,p.Thr193Phe,-0.3,-0.3,2,T523F +urn:mavedb:00000044-b-2#7705,NA,NA,p.Thr193Pro,-1.25,-1.25,1,T523P +urn:mavedb:00000044-b-2#7706,NA,NA,p.Thr193Pro,NA,-1.25,2,T523P +urn:mavedb:00000044-b-2#7711,NA,NA,p.Thr193Ser,0.23,-1.34,1,T523S +urn:mavedb:00000044-b-2#7712,NA,NA,p.Thr193Ser,-2.91,-1.34,2,T523S +urn:mavedb:00000044-b-2#7715,NA,NA,p.Thr193Trp,NA,NA,1,T523W +urn:mavedb:00000044-b-2#7716,NA,NA,p.Thr193Trp,NA,NA,2,T523W +urn:mavedb:00000044-b-2#7717,NA,NA,p.Thr193Tyr,-0.28,-0.25,1,T523Y +urn:mavedb:00000044-b-2#7718,NA,NA,p.Thr193Tyr,-0.21,-0.25,2,T523Y +urn:mavedb:00000044-b-2#7713,NA,NA,p.Thr193Val,NA,-0.09,1,T523V +urn:mavedb:00000044-b-2#7714,NA,NA,p.Thr193Val,-0.09,-0.09,2,T523V +urn:mavedb:00000044-b-2#8039,NA,NA,p.Thr201*,-4.59,-4.55,1,T531 +urn:mavedb:00000044-b-2#8040,NA,NA,p.Thr201*,-4.51,-4.55,2,T531 +urn:mavedb:00000044-b-2#8001,NA,NA,p.Thr201Ala,-0.01,-0.02,1,T531A +urn:mavedb:00000044-b-2#8002,NA,NA,p.Thr201Ala,-0.03,-0.02,2,T531A +urn:mavedb:00000044-b-2#8029,NA,NA,p.Thr201Arg,-0.06,-0.07,1,T531R +urn:mavedb:00000044-b-2#8030,NA,NA,p.Thr201Arg,-0.09,-0.07,2,T531R +urn:mavedb:00000044-b-2#8023,NA,NA,p.Thr201Asn,0.04,0.06,1,T531N +urn:mavedb:00000044-b-2#8024,NA,NA,p.Thr201Asn,0.09,0.06,2,T531N +urn:mavedb:00000044-b-2#8005,NA,NA,p.Thr201Asp,-0.02,0.03,1,T531D +urn:mavedb:00000044-b-2#8006,NA,NA,p.Thr201Asp,0.08,0.03,2,T531D +urn:mavedb:00000044-b-2#8003,NA,NA,p.Thr201Cys,0,-0.03,1,T531C +urn:mavedb:00000044-b-2#8004,NA,NA,p.Thr201Cys,-0.07,-0.03,2,T531C +urn:mavedb:00000044-b-2#8027,NA,NA,p.Thr201Gln,0.02,0,1,T531Q +urn:mavedb:00000044-b-2#8028,NA,NA,p.Thr201Gln,-0.01,0,2,T531Q +urn:mavedb:00000044-b-2#8007,NA,NA,p.Thr201Glu,-0.01,0.03,1,T531E +urn:mavedb:00000044-b-2#8008,NA,NA,p.Thr201Glu,0.06,0.03,2,T531E +urn:mavedb:00000044-b-2#8011,NA,NA,p.Thr201Gly,0.05,0.08,1,T531G +urn:mavedb:00000044-b-2#8012,NA,NA,p.Thr201Gly,0.11,0.08,2,T531G +urn:mavedb:00000044-b-2#8013,NA,NA,p.Thr201His,0.05,0.01,1,T531H +urn:mavedb:00000044-b-2#8014,NA,NA,p.Thr201His,-0.03,0.01,2,T531H +urn:mavedb:00000044-b-2#8015,NA,NA,p.Thr201Ile,-0.05,-0.05,1,T531I +urn:mavedb:00000044-b-2#8016,NA,NA,p.Thr201Ile,-0.06,-0.05,2,T531I +urn:mavedb:00000044-b-2#8019,NA,NA,p.Thr201Leu,0.04,0,1,T531L +urn:mavedb:00000044-b-2#8020,NA,NA,p.Thr201Leu,-0.03,0,2,T531L +urn:mavedb:00000044-b-2#8017,NA,NA,p.Thr201Lys,-0.03,-0.02,1,T531K +urn:mavedb:00000044-b-2#8018,NA,NA,p.Thr201Lys,0,-0.02,2,T531K +urn:mavedb:00000044-b-2#8021,NA,NA,p.Thr201Met,0,0,1,T531M +urn:mavedb:00000044-b-2#8022,NA,NA,p.Thr201Met,0.01,0,2,T531M +urn:mavedb:00000044-b-2#8009,NA,NA,p.Thr201Phe,-0.08,-0.02,1,T531F +urn:mavedb:00000044-b-2#8010,NA,NA,p.Thr201Phe,0.04,-0.02,2,T531F +urn:mavedb:00000044-b-2#8025,NA,NA,p.Thr201Pro,-0.03,-0.02,1,T531P +urn:mavedb:00000044-b-2#8026,NA,NA,p.Thr201Pro,-0.02,-0.02,2,T531P +urn:mavedb:00000044-b-2#8031,NA,NA,p.Thr201Ser,0.06,0.02,1,T531S +urn:mavedb:00000044-b-2#8032,NA,NA,p.Thr201Ser,-0.02,0.02,2,T531S +urn:mavedb:00000044-b-2#8035,NA,NA,p.Thr201Trp,-0.13,-0.08,1,T531W +urn:mavedb:00000044-b-2#8036,NA,NA,p.Thr201Trp,-0.04,-0.08,2,T531W +urn:mavedb:00000044-b-2#8037,NA,NA,p.Thr201Tyr,-0.03,-0.05,1,T531Y +urn:mavedb:00000044-b-2#8038,NA,NA,p.Thr201Tyr,-0.08,-0.05,2,T531Y +urn:mavedb:00000044-b-2#8033,NA,NA,p.Thr201Val,-0.07,-0.06,1,T531V +urn:mavedb:00000044-b-2#8034,NA,NA,p.Thr201Val,-0.05,-0.06,2,T531V +urn:mavedb:00000044-b-2#119,NA,NA,p.Thr3*,-4.65,-4.61,1,T333 +urn:mavedb:00000044-b-2#120,NA,NA,p.Thr3*,-4.57,-4.61,2,T333 +urn:mavedb:00000044-b-2#81,NA,NA,p.Thr3Ala,-0.44,-0.37,1,T333A +urn:mavedb:00000044-b-2#82,NA,NA,p.Thr3Ala,-0.29,-0.37,2,T333A +urn:mavedb:00000044-b-2#109,NA,NA,p.Thr3Arg,-0.53,-0.54,1,T333R +urn:mavedb:00000044-b-2#110,NA,NA,p.Thr3Arg,-0.56,-0.54,2,T333R +urn:mavedb:00000044-b-2#103,NA,NA,p.Thr3Asn,-0.39,-0.35,1,T333N +urn:mavedb:00000044-b-2#104,NA,NA,p.Thr3Asn,-0.31,-0.35,2,T333N +urn:mavedb:00000044-b-2#85,NA,NA,p.Thr3Asp,-0.29,-0.27,1,T333D +urn:mavedb:00000044-b-2#86,NA,NA,p.Thr3Asp,-0.25,-0.27,2,T333D +urn:mavedb:00000044-b-2#83,NA,NA,p.Thr3Cys,-0.57,-0.93,1,T333C +urn:mavedb:00000044-b-2#84,NA,NA,p.Thr3Cys,-1.29,-0.93,2,T333C +urn:mavedb:00000044-b-2#107,NA,NA,p.Thr3Gln,-0.29,-0.35,1,T333Q +urn:mavedb:00000044-b-2#108,NA,NA,p.Thr3Gln,-0.41,-0.35,2,T333Q +urn:mavedb:00000044-b-2#87,NA,NA,p.Thr3Glu,-0.2,-0.31,1,T333E +urn:mavedb:00000044-b-2#88,NA,NA,p.Thr3Glu,-0.43,-0.31,2,T333E +urn:mavedb:00000044-b-2#91,NA,NA,p.Thr3Gly,-0.45,-0.41,1,T333G +urn:mavedb:00000044-b-2#92,NA,NA,p.Thr3Gly,-0.37,-0.41,2,T333G +urn:mavedb:00000044-b-2#93,NA,NA,p.Thr3His,-0.29,-0.29,1,T333H +urn:mavedb:00000044-b-2#94,NA,NA,p.Thr3His,-0.29,-0.29,2,T333H +urn:mavedb:00000044-b-2#95,NA,NA,p.Thr3Ile,-1.24,-1.03,1,T333I +urn:mavedb:00000044-b-2#96,NA,NA,p.Thr3Ile,-0.82,-1.03,2,T333I +urn:mavedb:00000044-b-2#99,NA,NA,p.Thr3Leu,-0.61,-0.55,1,T333L +urn:mavedb:00000044-b-2#100,NA,NA,p.Thr3Leu,-0.48,-0.55,2,T333L +urn:mavedb:00000044-b-2#97,NA,NA,p.Thr3Lys,-0.18,-0.2,1,T333K +urn:mavedb:00000044-b-2#98,NA,NA,p.Thr3Lys,-0.22,-0.2,2,T333K +urn:mavedb:00000044-b-2#101,NA,NA,p.Thr3Met,-0.54,-0.47,1,T333M +urn:mavedb:00000044-b-2#102,NA,NA,p.Thr3Met,-0.39,-0.47,2,T333M +urn:mavedb:00000044-b-2#89,NA,NA,p.Thr3Phe,-0.74,-0.89,1,T333F +urn:mavedb:00000044-b-2#90,NA,NA,p.Thr3Phe,-1.04,-0.89,2,T333F +urn:mavedb:00000044-b-2#105,NA,NA,p.Thr3Pro,-0.21,-0.28,1,T333P +urn:mavedb:00000044-b-2#106,NA,NA,p.Thr3Pro,-0.35,-0.28,2,T333P +urn:mavedb:00000044-b-2#111,NA,NA,p.Thr3Ser,-0.03,-0.04,1,T333S +urn:mavedb:00000044-b-2#112,NA,NA,p.Thr3Ser,-0.05,-0.04,2,T333S +urn:mavedb:00000044-b-2#115,NA,NA,p.Thr3Trp,-0.68,-0.63,1,T333W +urn:mavedb:00000044-b-2#116,NA,NA,p.Thr3Trp,-0.58,-0.63,2,T333W +urn:mavedb:00000044-b-2#117,NA,NA,p.Thr3Tyr,-0.66,-0.62,1,T333Y +urn:mavedb:00000044-b-2#118,NA,NA,p.Thr3Tyr,-0.59,-0.62,2,T333Y +urn:mavedb:00000044-b-2#113,NA,NA,p.Thr3Val,-0.74,-0.56,1,T333V +urn:mavedb:00000044-b-2#114,NA,NA,p.Thr3Val,-0.38,-0.56,2,T333V +urn:mavedb:00000044-b-2#1839,NA,NA,p.Thr46*,-4.53,-4.51,1,T376 +urn:mavedb:00000044-b-2#1840,NA,NA,p.Thr46*,-4.5,-4.51,2,T376 +urn:mavedb:00000044-b-2#1801,NA,NA,p.Thr46Ala,-1.4,-1.1,1,T376A +urn:mavedb:00000044-b-2#1802,NA,NA,p.Thr46Ala,-0.81,-1.1,2,T376A +urn:mavedb:00000044-b-2#1829,NA,NA,p.Thr46Arg,-0.96,-1.04,1,T376R +urn:mavedb:00000044-b-2#1830,NA,NA,p.Thr46Arg,-1.12,-1.04,2,T376R +urn:mavedb:00000044-b-2#1823,NA,NA,p.Thr46Asn,-0.77,-0.7,1,T376N +urn:mavedb:00000044-b-2#1824,NA,NA,p.Thr46Asn,-0.64,-0.7,2,T376N +urn:mavedb:00000044-b-2#1805,NA,NA,p.Thr46Asp,-0.76,-0.84,1,T376D +urn:mavedb:00000044-b-2#1806,NA,NA,p.Thr46Asp,-0.91,-0.84,2,T376D +urn:mavedb:00000044-b-2#1803,NA,NA,p.Thr46Cys,-0.62,-0.84,1,T376C +urn:mavedb:00000044-b-2#1804,NA,NA,p.Thr46Cys,-1.05,-0.84,2,T376C +urn:mavedb:00000044-b-2#1827,NA,NA,p.Thr46Gln,0.05,-0.04,1,T376Q +urn:mavedb:00000044-b-2#1828,NA,NA,p.Thr46Gln,-0.13,-0.04,2,T376Q +urn:mavedb:00000044-b-2#1807,NA,NA,p.Thr46Glu,-0.38,-0.52,1,T376E +urn:mavedb:00000044-b-2#1808,NA,NA,p.Thr46Glu,-0.66,-0.52,2,T376E +urn:mavedb:00000044-b-2#1811,NA,NA,p.Thr46Gly,-1.87,-1.76,1,T376G +urn:mavedb:00000044-b-2#1812,NA,NA,p.Thr46Gly,-1.66,-1.76,2,T376G +urn:mavedb:00000044-b-2#1813,NA,NA,p.Thr46His,0.03,0.06,1,T376H +urn:mavedb:00000044-b-2#1814,NA,NA,p.Thr46His,0.1,0.06,2,T376H +urn:mavedb:00000044-b-2#1815,NA,NA,p.Thr46Ile,-0.23,-0.3,1,T376I +urn:mavedb:00000044-b-2#1816,NA,NA,p.Thr46Ile,-0.38,-0.3,2,T376I +urn:mavedb:00000044-b-2#1819,NA,NA,p.Thr46Leu,-0.21,-0.18,1,T376L +urn:mavedb:00000044-b-2#1820,NA,NA,p.Thr46Leu,-0.15,-0.18,2,T376L +urn:mavedb:00000044-b-2#1817,NA,NA,p.Thr46Lys,-0.67,-0.61,1,T376K +urn:mavedb:00000044-b-2#1818,NA,NA,p.Thr46Lys,-0.56,-0.61,2,T376K +urn:mavedb:00000044-b-2#1821,NA,NA,p.Thr46Met,-0.18,-0.15,1,T376M +urn:mavedb:00000044-b-2#1822,NA,NA,p.Thr46Met,-0.13,-0.15,2,T376M +urn:mavedb:00000044-b-2#1809,NA,NA,p.Thr46Phe,-0.68,-0.57,1,T376F +urn:mavedb:00000044-b-2#1810,NA,NA,p.Thr46Phe,-0.46,-0.57,2,T376F +urn:mavedb:00000044-b-2#1825,NA,NA,p.Thr46Pro,-2.74,-2.63,1,T376P +urn:mavedb:00000044-b-2#1826,NA,NA,p.Thr46Pro,-2.52,-2.63,2,T376P +urn:mavedb:00000044-b-2#1831,NA,NA,p.Thr46Ser,-0.25,-0.22,1,T376S +urn:mavedb:00000044-b-2#1832,NA,NA,p.Thr46Ser,-0.19,-0.22,2,T376S +urn:mavedb:00000044-b-2#1835,NA,NA,p.Thr46Trp,-0.36,-0.37,1,T376W +urn:mavedb:00000044-b-2#1836,NA,NA,p.Thr46Trp,-0.38,-0.37,2,T376W +urn:mavedb:00000044-b-2#1837,NA,NA,p.Thr46Tyr,-0.05,-0.04,1,T376Y +urn:mavedb:00000044-b-2#1838,NA,NA,p.Thr46Tyr,-0.02,-0.04,2,T376Y +urn:mavedb:00000044-b-2#1833,NA,NA,p.Thr46Val,-0.23,-0.21,1,T376V +urn:mavedb:00000044-b-2#1834,NA,NA,p.Thr46Val,-0.2,-0.21,2,T376V +urn:mavedb:00000044-b-2#2199,NA,NA,p.Thr55*,-4.56,-4.54,1,T385 +urn:mavedb:00000044-b-2#2200,NA,NA,p.Thr55*,-4.53,-4.54,2,T385 +urn:mavedb:00000044-b-2#2161,NA,NA,p.Thr55Ala,-0.04,-0.03,1,T385A +urn:mavedb:00000044-b-2#2162,NA,NA,p.Thr55Ala,-0.02,-0.03,2,T385A +urn:mavedb:00000044-b-2#2189,NA,NA,p.Thr55Arg,0.04,-0.02,1,T385R +urn:mavedb:00000044-b-2#2190,NA,NA,p.Thr55Arg,-0.08,-0.02,2,T385R +urn:mavedb:00000044-b-2#2183,NA,NA,p.Thr55Asn,0.02,0.03,1,T385N +urn:mavedb:00000044-b-2#2184,NA,NA,p.Thr55Asn,0.05,0.03,2,T385N +urn:mavedb:00000044-b-2#2165,NA,NA,p.Thr55Asp,0.28,0.21,1,T385D +urn:mavedb:00000044-b-2#2166,NA,NA,p.Thr55Asp,0.14,0.21,2,T385D +urn:mavedb:00000044-b-2#2163,NA,NA,p.Thr55Cys,-0.3,-0.43,1,T385C +urn:mavedb:00000044-b-2#2164,NA,NA,p.Thr55Cys,-0.55,-0.43,2,T385C +urn:mavedb:00000044-b-2#2187,NA,NA,p.Thr55Gln,0.05,0.03,1,T385Q +urn:mavedb:00000044-b-2#2188,NA,NA,p.Thr55Gln,0.01,0.03,2,T385Q +urn:mavedb:00000044-b-2#2167,NA,NA,p.Thr55Glu,0.42,0.28,1,T385E +urn:mavedb:00000044-b-2#2168,NA,NA,p.Thr55Glu,0.14,0.28,2,T385E +urn:mavedb:00000044-b-2#2171,NA,NA,p.Thr55Gly,-0.1,-0.09,1,T385G +urn:mavedb:00000044-b-2#2172,NA,NA,p.Thr55Gly,-0.08,-0.09,2,T385G +urn:mavedb:00000044-b-2#2173,NA,NA,p.Thr55His,-0.02,-0.02,1,T385H +urn:mavedb:00000044-b-2#2174,NA,NA,p.Thr55His,-0.01,-0.02,2,T385H +urn:mavedb:00000044-b-2#2175,NA,NA,p.Thr55Ile,-0.18,-0.27,1,T385I +urn:mavedb:00000044-b-2#2176,NA,NA,p.Thr55Ile,-0.36,-0.27,2,T385I +urn:mavedb:00000044-b-2#2179,NA,NA,p.Thr55Leu,-0.06,-0.05,1,T385L +urn:mavedb:00000044-b-2#2180,NA,NA,p.Thr55Leu,-0.04,-0.05,2,T385L +urn:mavedb:00000044-b-2#2177,NA,NA,p.Thr55Lys,0.17,0.07,1,T385K +urn:mavedb:00000044-b-2#2178,NA,NA,p.Thr55Lys,-0.03,0.07,2,T385K +urn:mavedb:00000044-b-2#2181,NA,NA,p.Thr55Met,-0.01,-0.08,1,T385M +urn:mavedb:00000044-b-2#2182,NA,NA,p.Thr55Met,-0.15,-0.08,2,T385M +urn:mavedb:00000044-b-2#2169,NA,NA,p.Thr55Phe,-0.15,-0.15,1,T385F +urn:mavedb:00000044-b-2#2170,NA,NA,p.Thr55Phe,-0.15,-0.15,2,T385F +urn:mavedb:00000044-b-2#2185,NA,NA,p.Thr55Pro,-0.66,-0.6,1,T385P +urn:mavedb:00000044-b-2#2186,NA,NA,p.Thr55Pro,-0.54,-0.6,2,T385P +urn:mavedb:00000044-b-2#2191,NA,NA,p.Thr55Ser,-0.02,0,1,T385S +urn:mavedb:00000044-b-2#2192,NA,NA,p.Thr55Ser,0.02,0,2,T385S +urn:mavedb:00000044-b-2#2195,NA,NA,p.Thr55Trp,-0.31,-0.21,1,T385W +urn:mavedb:00000044-b-2#2196,NA,NA,p.Thr55Trp,-0.12,-0.21,2,T385W +urn:mavedb:00000044-b-2#2197,NA,NA,p.Thr55Tyr,-0.02,-0.02,1,T385Y +urn:mavedb:00000044-b-2#2198,NA,NA,p.Thr55Tyr,-0.01,-0.02,2,T385Y +urn:mavedb:00000044-b-2#2193,NA,NA,p.Thr55Val,-0.45,-0.4,1,T385V +urn:mavedb:00000044-b-2#2194,NA,NA,p.Thr55Val,-0.36,-0.4,2,T385V +urn:mavedb:00000044-b-2#2519,NA,NA,p.Thr63*,-4.58,-4.56,1,T393 +urn:mavedb:00000044-b-2#2520,NA,NA,p.Thr63*,-4.54,-4.56,2,T393 +urn:mavedb:00000044-b-2#2481,NA,NA,p.Thr63Ala,-0.02,-0.11,1,T393A +urn:mavedb:00000044-b-2#2482,NA,NA,p.Thr63Ala,-0.21,-0.11,2,T393A +urn:mavedb:00000044-b-2#2509,NA,NA,p.Thr63Arg,-0.21,-0.18,1,T393R +urn:mavedb:00000044-b-2#2510,NA,NA,p.Thr63Arg,-0.14,-0.18,2,T393R +urn:mavedb:00000044-b-2#2503,NA,NA,p.Thr63Asn,-0.12,-0.16,1,T393N +urn:mavedb:00000044-b-2#2504,NA,NA,p.Thr63Asn,-0.2,-0.16,2,T393N +urn:mavedb:00000044-b-2#2485,NA,NA,p.Thr63Asp,-0.3,-0.27,1,T393D +urn:mavedb:00000044-b-2#2486,NA,NA,p.Thr63Asp,-0.25,-0.27,2,T393D +urn:mavedb:00000044-b-2#2483,NA,NA,p.Thr63Cys,-0.59,-0.66,1,T393C +urn:mavedb:00000044-b-2#2484,NA,NA,p.Thr63Cys,-0.72,-0.66,2,T393C +urn:mavedb:00000044-b-2#2507,NA,NA,p.Thr63Gln,0.04,-0.08,1,T393Q +urn:mavedb:00000044-b-2#2508,NA,NA,p.Thr63Gln,-0.19,-0.08,2,T393Q +urn:mavedb:00000044-b-2#2487,NA,NA,p.Thr63Glu,-0.15,-0.28,1,T393E +urn:mavedb:00000044-b-2#2488,NA,NA,p.Thr63Glu,-0.4,-0.28,2,T393E +urn:mavedb:00000044-b-2#2491,NA,NA,p.Thr63Gly,-0.26,-0.31,1,T393G +urn:mavedb:00000044-b-2#2492,NA,NA,p.Thr63Gly,-0.36,-0.31,2,T393G +urn:mavedb:00000044-b-2#2493,NA,NA,p.Thr63His,-0.31,-0.3,1,T393H +urn:mavedb:00000044-b-2#2494,NA,NA,p.Thr63His,-0.29,-0.3,2,T393H +urn:mavedb:00000044-b-2#2495,NA,NA,p.Thr63Ile,-0.48,-0.47,1,T393I +urn:mavedb:00000044-b-2#2496,NA,NA,p.Thr63Ile,-0.46,-0.47,2,T393I +urn:mavedb:00000044-b-2#2499,NA,NA,p.Thr63Leu,-0.54,-0.56,1,T393L +urn:mavedb:00000044-b-2#2500,NA,NA,p.Thr63Leu,-0.57,-0.56,2,T393L +urn:mavedb:00000044-b-2#2497,NA,NA,p.Thr63Lys,-0.04,-0.01,1,T393K +urn:mavedb:00000044-b-2#2498,NA,NA,p.Thr63Lys,0.01,-0.01,2,T393K +urn:mavedb:00000044-b-2#2501,NA,NA,p.Thr63Met,-0.38,-0.75,1,T393M +urn:mavedb:00000044-b-2#2502,NA,NA,p.Thr63Met,-1.13,-0.75,2,T393M +urn:mavedb:00000044-b-2#2489,NA,NA,p.Thr63Phe,-1.29,-1.27,1,T393F +urn:mavedb:00000044-b-2#2490,NA,NA,p.Thr63Phe,-1.26,-1.27,2,T393F +urn:mavedb:00000044-b-2#2505,NA,NA,p.Thr63Pro,-1.26,-1.37,1,T393P +urn:mavedb:00000044-b-2#2506,NA,NA,p.Thr63Pro,-1.48,-1.37,2,T393P +urn:mavedb:00000044-b-2#2511,NA,NA,p.Thr63Ser,-0.06,-0.05,1,T393S +urn:mavedb:00000044-b-2#2512,NA,NA,p.Thr63Ser,-0.05,-0.05,2,T393S +urn:mavedb:00000044-b-2#2515,NA,NA,p.Thr63Trp,-1.29,-1.49,1,T393W +urn:mavedb:00000044-b-2#2516,NA,NA,p.Thr63Trp,-1.69,-1.49,2,T393W +urn:mavedb:00000044-b-2#2517,NA,NA,p.Thr63Tyr,-0.35,-0.43,1,T393Y +urn:mavedb:00000044-b-2#2518,NA,NA,p.Thr63Tyr,-0.51,-0.43,2,T393Y +urn:mavedb:00000044-b-2#2513,NA,NA,p.Thr63Val,-0.26,-0.28,1,T393V +urn:mavedb:00000044-b-2#2514,NA,NA,p.Thr63Val,-0.29,-0.28,2,T393V +urn:mavedb:00000044-b-2#3399,NA,NA,p.Thr85*,-4.63,-4.57,1,T415 +urn:mavedb:00000044-b-2#3400,NA,NA,p.Thr85*,-4.5,-4.57,2,T415 +urn:mavedb:00000044-b-2#3361,NA,NA,p.Thr85Ala,-0.31,-0.33,1,T415A +urn:mavedb:00000044-b-2#3362,NA,NA,p.Thr85Ala,-0.35,-0.33,2,T415A +urn:mavedb:00000044-b-2#3389,NA,NA,p.Thr85Arg,0.04,0.02,1,T415R +urn:mavedb:00000044-b-2#3390,NA,NA,p.Thr85Arg,0,0.02,2,T415R +urn:mavedb:00000044-b-2#3383,NA,NA,p.Thr85Asn,-0.28,-0.29,1,T415N +urn:mavedb:00000044-b-2#3384,NA,NA,p.Thr85Asn,-0.31,-0.29,2,T415N +urn:mavedb:00000044-b-2#3365,NA,NA,p.Thr85Asp,-0.69,-0.76,1,T415D +urn:mavedb:00000044-b-2#3366,NA,NA,p.Thr85Asp,-0.83,-0.76,2,T415D +urn:mavedb:00000044-b-2#3363,NA,NA,p.Thr85Cys,-1,-1.15,1,T415C +urn:mavedb:00000044-b-2#3364,NA,NA,p.Thr85Cys,-1.3,-1.15,2,T415C +urn:mavedb:00000044-b-2#3387,NA,NA,p.Thr85Gln,-0.15,-0.1,1,T415Q +urn:mavedb:00000044-b-2#3388,NA,NA,p.Thr85Gln,-0.06,-0.1,2,T415Q +urn:mavedb:00000044-b-2#3367,NA,NA,p.Thr85Glu,-0.46,-0.5,1,T415E +urn:mavedb:00000044-b-2#3368,NA,NA,p.Thr85Glu,-0.55,-0.5,2,T415E +urn:mavedb:00000044-b-2#3371,NA,NA,p.Thr85Gly,-0.6,-0.61,1,T415G +urn:mavedb:00000044-b-2#3372,NA,NA,p.Thr85Gly,-0.62,-0.61,2,T415G +urn:mavedb:00000044-b-2#3373,NA,NA,p.Thr85His,0.05,0.13,1,T415H +urn:mavedb:00000044-b-2#3374,NA,NA,p.Thr85His,0.2,0.13,2,T415H +urn:mavedb:00000044-b-2#3375,NA,NA,p.Thr85Ile,-0.62,-0.61,1,T415I +urn:mavedb:00000044-b-2#3376,NA,NA,p.Thr85Ile,-0.61,-0.61,2,T415I +urn:mavedb:00000044-b-2#3379,NA,NA,p.Thr85Leu,-1.11,-1.12,1,T415L +urn:mavedb:00000044-b-2#3380,NA,NA,p.Thr85Leu,-1.12,-1.12,2,T415L +urn:mavedb:00000044-b-2#3377,NA,NA,p.Thr85Lys,-0.02,-0.09,1,T415K +urn:mavedb:00000044-b-2#3378,NA,NA,p.Thr85Lys,-0.16,-0.09,2,T415K +urn:mavedb:00000044-b-2#3381,NA,NA,p.Thr85Met,-0.58,-0.56,1,T415M +urn:mavedb:00000044-b-2#3382,NA,NA,p.Thr85Met,-0.53,-0.56,2,T415M +urn:mavedb:00000044-b-2#3369,NA,NA,p.Thr85Phe,-1.13,-1.07,1,T415F +urn:mavedb:00000044-b-2#3370,NA,NA,p.Thr85Phe,-1.01,-1.07,2,T415F +urn:mavedb:00000044-b-2#3385,NA,NA,p.Thr85Pro,-1.05,-1.01,1,T415P +urn:mavedb:00000044-b-2#3386,NA,NA,p.Thr85Pro,-0.98,-1.01,2,T415P +urn:mavedb:00000044-b-2#3391,NA,NA,p.Thr85Ser,-0.01,-0.03,1,T415S +urn:mavedb:00000044-b-2#3392,NA,NA,p.Thr85Ser,-0.04,-0.03,2,T415S +urn:mavedb:00000044-b-2#3395,NA,NA,p.Thr85Trp,-1.46,-1.5,1,T415W +urn:mavedb:00000044-b-2#3396,NA,NA,p.Thr85Trp,-1.54,-1.5,2,T415W +urn:mavedb:00000044-b-2#3397,NA,NA,p.Thr85Tyr,-0.95,-0.86,1,T415Y +urn:mavedb:00000044-b-2#3398,NA,NA,p.Thr85Tyr,-0.77,-0.86,2,T415Y +urn:mavedb:00000044-b-2#3393,NA,NA,p.Thr85Val,-0.3,-0.29,1,T415V +urn:mavedb:00000044-b-2#3394,NA,NA,p.Thr85Val,-0.27,-0.29,2,T415V +urn:mavedb:00000044-b-2#4239,NA,NA,p.Trp106*,-4.61,-4.56,1,W436 +urn:mavedb:00000044-b-2#4240,NA,NA,p.Trp106*,-4.52,-4.56,2,W436 +urn:mavedb:00000044-b-2#4201,NA,NA,p.Trp106Ala,-2.61,-2.7,1,W436A +urn:mavedb:00000044-b-2#4202,NA,NA,p.Trp106Ala,-2.8,-2.7,2,W436A +urn:mavedb:00000044-b-2#4229,NA,NA,p.Trp106Arg,-2.42,-2.36,1,W436R +urn:mavedb:00000044-b-2#4230,NA,NA,p.Trp106Arg,-2.29,-2.36,2,W436R +urn:mavedb:00000044-b-2#4223,NA,NA,p.Trp106Asn,-2.8,-2.7,1,W436N +urn:mavedb:00000044-b-2#4224,NA,NA,p.Trp106Asn,-2.6,-2.7,2,W436N +urn:mavedb:00000044-b-2#4205,NA,NA,p.Trp106Asp,-3.03,-2.97,1,W436D +urn:mavedb:00000044-b-2#4206,NA,NA,p.Trp106Asp,-2.91,-2.97,2,W436D +urn:mavedb:00000044-b-2#4203,NA,NA,p.Trp106Cys,-2.48,-2.42,1,W436C +urn:mavedb:00000044-b-2#4204,NA,NA,p.Trp106Cys,-2.36,-2.42,2,W436C +urn:mavedb:00000044-b-2#4227,NA,NA,p.Trp106Gln,-2.33,-2.33,1,W436Q +urn:mavedb:00000044-b-2#4228,NA,NA,p.Trp106Gln,-2.33,-2.33,2,W436Q +urn:mavedb:00000044-b-2#4207,NA,NA,p.Trp106Glu,-2.8,-2.79,1,W436E +urn:mavedb:00000044-b-2#4208,NA,NA,p.Trp106Glu,-2.77,-2.79,2,W436E +urn:mavedb:00000044-b-2#4211,NA,NA,p.Trp106Gly,-2.94,-2.86,1,W436G +urn:mavedb:00000044-b-2#4212,NA,NA,p.Trp106Gly,-2.79,-2.86,2,W436G +urn:mavedb:00000044-b-2#4213,NA,NA,p.Trp106His,-2.87,-2.76,1,W436H +urn:mavedb:00000044-b-2#4214,NA,NA,p.Trp106His,-2.65,-2.76,2,W436H +urn:mavedb:00000044-b-2#4215,NA,NA,p.Trp106Ile,-2.52,-2.29,1,W436I +urn:mavedb:00000044-b-2#4216,NA,NA,p.Trp106Ile,-2.06,-2.29,2,W436I +urn:mavedb:00000044-b-2#4219,NA,NA,p.Trp106Leu,-2.4,-2.37,1,W436L +urn:mavedb:00000044-b-2#4220,NA,NA,p.Trp106Leu,-2.35,-2.37,2,W436L +urn:mavedb:00000044-b-2#4217,NA,NA,p.Trp106Lys,-2.45,-2.46,1,W436K +urn:mavedb:00000044-b-2#4218,NA,NA,p.Trp106Lys,-2.47,-2.46,2,W436K +urn:mavedb:00000044-b-2#4221,NA,NA,p.Trp106Met,-1.83,-1.8,1,W436M +urn:mavedb:00000044-b-2#4222,NA,NA,p.Trp106Met,-1.77,-1.8,2,W436M +urn:mavedb:00000044-b-2#4209,NA,NA,p.Trp106Phe,-1.39,-1.38,1,W436F +urn:mavedb:00000044-b-2#4210,NA,NA,p.Trp106Phe,-1.38,-1.38,2,W436F +urn:mavedb:00000044-b-2#4225,NA,NA,p.Trp106Pro,-2.94,-2.88,1,W436P +urn:mavedb:00000044-b-2#4226,NA,NA,p.Trp106Pro,-2.81,-2.88,2,W436P +urn:mavedb:00000044-b-2#4231,NA,NA,p.Trp106Ser,-2.52,-2.48,1,W436S +urn:mavedb:00000044-b-2#4232,NA,NA,p.Trp106Ser,-2.43,-2.48,2,W436S +urn:mavedb:00000044-b-2#4233,NA,NA,p.Trp106Thr,-2.35,-2.31,1,W436T +urn:mavedb:00000044-b-2#4234,NA,NA,p.Trp106Thr,-2.28,-2.31,2,W436T +urn:mavedb:00000044-b-2#4237,NA,NA,p.Trp106Tyr,-1.91,-1.82,1,W436Y +urn:mavedb:00000044-b-2#4238,NA,NA,p.Trp106Tyr,-1.74,-1.82,2,W436Y +urn:mavedb:00000044-b-2#4235,NA,NA,p.Trp106Val,-2.38,-2.37,1,W436V +urn:mavedb:00000044-b-2#4236,NA,NA,p.Trp106Val,-2.37,-2.37,2,W436V +urn:mavedb:00000044-b-2#919,NA,NA,p.Trp23*,-4.63,-4.62,1,W353 +urn:mavedb:00000044-b-2#920,NA,NA,p.Trp23*,-4.6,-4.62,2,W353 +urn:mavedb:00000044-b-2#881,NA,NA,p.Trp23Ala,-2.23,-2.15,1,W353A +urn:mavedb:00000044-b-2#882,NA,NA,p.Trp23Ala,-2.08,-2.15,2,W353A +urn:mavedb:00000044-b-2#909,NA,NA,p.Trp23Arg,-2.56,-2.52,1,W353R +urn:mavedb:00000044-b-2#910,NA,NA,p.Trp23Arg,-2.48,-2.52,2,W353R +urn:mavedb:00000044-b-2#903,NA,NA,p.Trp23Asn,-2.16,-2.19,1,W353N +urn:mavedb:00000044-b-2#904,NA,NA,p.Trp23Asn,-2.23,-2.19,2,W353N +urn:mavedb:00000044-b-2#885,NA,NA,p.Trp23Asp,-2.61,-2.44,1,W353D +urn:mavedb:00000044-b-2#886,NA,NA,p.Trp23Asp,-2.28,-2.44,2,W353D +urn:mavedb:00000044-b-2#883,NA,NA,p.Trp23Cys,-2.55,-2.53,1,W353C +urn:mavedb:00000044-b-2#884,NA,NA,p.Trp23Cys,-2.51,-2.53,2,W353C +urn:mavedb:00000044-b-2#907,NA,NA,p.Trp23Gln,-2.34,-2.42,1,W353Q +urn:mavedb:00000044-b-2#908,NA,NA,p.Trp23Gln,-2.5,-2.42,2,W353Q +urn:mavedb:00000044-b-2#887,NA,NA,p.Trp23Glu,-2.07,-2.12,1,W353E +urn:mavedb:00000044-b-2#888,NA,NA,p.Trp23Glu,-2.17,-2.12,2,W353E +urn:mavedb:00000044-b-2#891,NA,NA,p.Trp23Gly,-2.34,-2.27,1,W353G +urn:mavedb:00000044-b-2#892,NA,NA,p.Trp23Gly,-2.21,-2.27,2,W353G +urn:mavedb:00000044-b-2#893,NA,NA,p.Trp23His,-2.85,-2.49,1,W353H +urn:mavedb:00000044-b-2#894,NA,NA,p.Trp23His,-2.13,-2.49,2,W353H +urn:mavedb:00000044-b-2#895,NA,NA,p.Trp23Ile,-2.2,-2.49,1,W353I +urn:mavedb:00000044-b-2#896,NA,NA,p.Trp23Ile,-2.78,-2.49,2,W353I +urn:mavedb:00000044-b-2#899,NA,NA,p.Trp23Leu,-2.57,-2.62,1,W353L +urn:mavedb:00000044-b-2#900,NA,NA,p.Trp23Leu,-2.67,-2.62,2,W353L +urn:mavedb:00000044-b-2#897,NA,NA,p.Trp23Lys,-2.32,-2.25,1,W353K +urn:mavedb:00000044-b-2#898,NA,NA,p.Trp23Lys,-2.19,-2.25,2,W353K +urn:mavedb:00000044-b-2#901,NA,NA,p.Trp23Met,-2.44,-2.51,1,W353M +urn:mavedb:00000044-b-2#902,NA,NA,p.Trp23Met,-2.59,-2.51,2,W353M +urn:mavedb:00000044-b-2#889,NA,NA,p.Trp23Phe,-0.56,-0.83,1,W353F +urn:mavedb:00000044-b-2#890,NA,NA,p.Trp23Phe,-1.1,-0.83,2,W353F +urn:mavedb:00000044-b-2#905,NA,NA,p.Trp23Pro,-2.1,-2.04,1,W353P +urn:mavedb:00000044-b-2#906,NA,NA,p.Trp23Pro,-1.98,-2.04,2,W353P +urn:mavedb:00000044-b-2#911,NA,NA,p.Trp23Ser,-2.12,-2.02,1,W353S +urn:mavedb:00000044-b-2#912,NA,NA,p.Trp23Ser,-1.92,-2.02,2,W353S +urn:mavedb:00000044-b-2#913,NA,NA,p.Trp23Thr,-2.21,-2.13,1,W353T +urn:mavedb:00000044-b-2#914,NA,NA,p.Trp23Thr,-2.05,-2.13,2,W353T +urn:mavedb:00000044-b-2#917,NA,NA,p.Trp23Tyr,-1.49,-1.58,1,W353Y +urn:mavedb:00000044-b-2#918,NA,NA,p.Trp23Tyr,-1.67,-1.58,2,W353Y +urn:mavedb:00000044-b-2#915,NA,NA,p.Trp23Val,-2.56,-2.47,1,W353V +urn:mavedb:00000044-b-2#916,NA,NA,p.Trp23Val,-2.39,-2.47,2,W353V +urn:mavedb:00000044-b-2#4759,NA,NA,p.Tyr119*,-4.57,-4.55,1,Y449 +urn:mavedb:00000044-b-2#4760,NA,NA,p.Tyr119*,-4.54,-4.55,2,Y449 +urn:mavedb:00000044-b-2#4721,NA,NA,p.Tyr119Ala,0.11,0.05,1,Y449A +urn:mavedb:00000044-b-2#4722,NA,NA,p.Tyr119Ala,-0.01,0.05,2,Y449A +urn:mavedb:00000044-b-2#4749,NA,NA,p.Tyr119Arg,-0.01,-0.02,1,Y449R +urn:mavedb:00000044-b-2#4750,NA,NA,p.Tyr119Arg,-0.04,-0.02,2,Y449R +urn:mavedb:00000044-b-2#4743,NA,NA,p.Tyr119Asn,0.04,0.07,1,Y449N +urn:mavedb:00000044-b-2#4744,NA,NA,p.Tyr119Asn,0.1,0.07,2,Y449N +urn:mavedb:00000044-b-2#4725,NA,NA,p.Tyr119Asp,0.29,0.29,1,Y449D +urn:mavedb:00000044-b-2#4726,NA,NA,p.Tyr119Asp,0.28,0.29,2,Y449D +urn:mavedb:00000044-b-2#4723,NA,NA,p.Tyr119Cys,-0.17,-0.17,1,Y449C +urn:mavedb:00000044-b-2#4724,NA,NA,p.Tyr119Cys,-0.18,-0.17,2,Y449C +urn:mavedb:00000044-b-2#4747,NA,NA,p.Tyr119Gln,0.2,0.18,1,Y449Q +urn:mavedb:00000044-b-2#4748,NA,NA,p.Tyr119Gln,0.15,0.18,2,Y449Q +urn:mavedb:00000044-b-2#4727,NA,NA,p.Tyr119Glu,0.06,0.12,1,Y449E +urn:mavedb:00000044-b-2#4728,NA,NA,p.Tyr119Glu,0.17,0.12,2,Y449E +urn:mavedb:00000044-b-2#4731,NA,NA,p.Tyr119Gly,0.06,0.06,1,Y449G +urn:mavedb:00000044-b-2#4732,NA,NA,p.Tyr119Gly,0.06,0.06,2,Y449G +urn:mavedb:00000044-b-2#4733,NA,NA,p.Tyr119His,0.06,0.12,1,Y449H +urn:mavedb:00000044-b-2#4734,NA,NA,p.Tyr119His,0.19,0.12,2,Y449H +urn:mavedb:00000044-b-2#4735,NA,NA,p.Tyr119Ile,-0.12,-0.21,1,Y449I +urn:mavedb:00000044-b-2#4736,NA,NA,p.Tyr119Ile,-0.29,-0.21,2,Y449I +urn:mavedb:00000044-b-2#4739,NA,NA,p.Tyr119Leu,-0.28,-0.3,1,Y449L +urn:mavedb:00000044-b-2#4740,NA,NA,p.Tyr119Leu,-0.32,-0.3,2,Y449L +urn:mavedb:00000044-b-2#4737,NA,NA,p.Tyr119Lys,0.01,-0.03,1,Y449K +urn:mavedb:00000044-b-2#4738,NA,NA,p.Tyr119Lys,-0.07,-0.03,2,Y449K +urn:mavedb:00000044-b-2#4741,NA,NA,p.Tyr119Met,0,-0.04,1,Y449M +urn:mavedb:00000044-b-2#4742,NA,NA,p.Tyr119Met,-0.07,-0.04,2,Y449M +urn:mavedb:00000044-b-2#4729,NA,NA,p.Tyr119Phe,-0.08,-0.03,1,Y449F +urn:mavedb:00000044-b-2#4730,NA,NA,p.Tyr119Phe,0.02,-0.03,2,Y449F +urn:mavedb:00000044-b-2#4745,NA,NA,p.Tyr119Pro,0.05,0.07,1,Y449P +urn:mavedb:00000044-b-2#4746,NA,NA,p.Tyr119Pro,0.1,0.07,2,Y449P +urn:mavedb:00000044-b-2#4751,NA,NA,p.Tyr119Ser,0.12,0.12,1,Y449S +urn:mavedb:00000044-b-2#4752,NA,NA,p.Tyr119Ser,0.12,0.12,2,Y449S +urn:mavedb:00000044-b-2#4753,NA,NA,p.Tyr119Thr,0.03,0.09,1,Y449T +urn:mavedb:00000044-b-2#4754,NA,NA,p.Tyr119Thr,0.15,0.09,2,Y449T +urn:mavedb:00000044-b-2#4757,NA,NA,p.Tyr119Trp,-0.38,-0.23,1,Y449W +urn:mavedb:00000044-b-2#4758,NA,NA,p.Tyr119Trp,-0.09,-0.23,2,Y449W +urn:mavedb:00000044-b-2#4755,NA,NA,p.Tyr119Val,-0.08,-0.1,1,Y449V +urn:mavedb:00000044-b-2#4756,NA,NA,p.Tyr119Val,-0.11,-0.1,2,Y449V +urn:mavedb:00000044-b-2#4839,NA,NA,p.Tyr121*,-4.61,-4.56,1,Y451 +urn:mavedb:00000044-b-2#4840,NA,NA,p.Tyr121*,-4.51,-4.56,2,Y451 +urn:mavedb:00000044-b-2#4801,NA,NA,p.Tyr121Ala,-1.13,-1.27,1,Y451A +urn:mavedb:00000044-b-2#4802,NA,NA,p.Tyr121Ala,-1.41,-1.27,2,Y451A +urn:mavedb:00000044-b-2#4829,NA,NA,p.Tyr121Arg,-1.98,-1.89,1,Y451R +urn:mavedb:00000044-b-2#4830,NA,NA,p.Tyr121Arg,-1.8,-1.89,2,Y451R +urn:mavedb:00000044-b-2#4823,NA,NA,p.Tyr121Asn,-1.35,-1.58,1,Y451N +urn:mavedb:00000044-b-2#4824,NA,NA,p.Tyr121Asn,-1.81,-1.58,2,Y451N +urn:mavedb:00000044-b-2#4805,NA,NA,p.Tyr121Asp,-2.19,-2.21,1,Y451D +urn:mavedb:00000044-b-2#4806,NA,NA,p.Tyr121Asp,-2.23,-2.21,2,Y451D +urn:mavedb:00000044-b-2#4803,NA,NA,p.Tyr121Cys,-1.32,-1.26,1,Y451C +urn:mavedb:00000044-b-2#4804,NA,NA,p.Tyr121Cys,-1.21,-1.26,2,Y451C +urn:mavedb:00000044-b-2#4827,NA,NA,p.Tyr121Gln,-0.55,-0.72,1,Y451Q +urn:mavedb:00000044-b-2#4828,NA,NA,p.Tyr121Gln,-0.88,-0.72,2,Y451Q +urn:mavedb:00000044-b-2#4807,NA,NA,p.Tyr121Glu,-2.5,-2.2,1,Y451E +urn:mavedb:00000044-b-2#4808,NA,NA,p.Tyr121Glu,-1.9,-2.2,2,Y451E +urn:mavedb:00000044-b-2#4811,NA,NA,p.Tyr121Gly,-2.18,-2.16,1,Y451G +urn:mavedb:00000044-b-2#4812,NA,NA,p.Tyr121Gly,-2.15,-2.16,2,Y451G +urn:mavedb:00000044-b-2#4813,NA,NA,p.Tyr121His,-0.68,-0.42,1,Y451H +urn:mavedb:00000044-b-2#4814,NA,NA,p.Tyr121His,-0.17,-0.42,2,Y451H +urn:mavedb:00000044-b-2#4815,NA,NA,p.Tyr121Ile,-0.7,-0.89,1,Y451I +urn:mavedb:00000044-b-2#4816,NA,NA,p.Tyr121Ile,-1.07,-0.89,2,Y451I +urn:mavedb:00000044-b-2#4819,NA,NA,p.Tyr121Leu,-0.11,-0.15,1,Y451L +urn:mavedb:00000044-b-2#4820,NA,NA,p.Tyr121Leu,-0.19,-0.15,2,Y451L +urn:mavedb:00000044-b-2#4817,NA,NA,p.Tyr121Lys,-1.33,-1.38,1,Y451K +urn:mavedb:00000044-b-2#4818,NA,NA,p.Tyr121Lys,-1.43,-1.38,2,Y451K +urn:mavedb:00000044-b-2#4821,NA,NA,p.Tyr121Met,-0.54,-0.58,1,Y451M +urn:mavedb:00000044-b-2#4822,NA,NA,p.Tyr121Met,-0.61,-0.58,2,Y451M +urn:mavedb:00000044-b-2#4809,NA,NA,p.Tyr121Phe,-0.25,-0.23,1,Y451F +urn:mavedb:00000044-b-2#4810,NA,NA,p.Tyr121Phe,-0.2,-0.23,2,Y451F +urn:mavedb:00000044-b-2#4825,NA,NA,p.Tyr121Pro,-1.24,-1.23,1,Y451P +urn:mavedb:00000044-b-2#4826,NA,NA,p.Tyr121Pro,-1.22,-1.23,2,Y451P +urn:mavedb:00000044-b-2#4831,NA,NA,p.Tyr121Ser,-1.34,-1.45,1,Y451S +urn:mavedb:00000044-b-2#4832,NA,NA,p.Tyr121Ser,-1.57,-1.45,2,Y451S +urn:mavedb:00000044-b-2#4833,NA,NA,p.Tyr121Thr,-1.91,-1.77,1,Y451T +urn:mavedb:00000044-b-2#4834,NA,NA,p.Tyr121Thr,-1.63,-1.77,2,Y451T +urn:mavedb:00000044-b-2#4837,NA,NA,p.Tyr121Trp,-1.83,-1.76,1,Y451W +urn:mavedb:00000044-b-2#4838,NA,NA,p.Tyr121Trp,-1.68,-1.76,2,Y451W +urn:mavedb:00000044-b-2#4835,NA,NA,p.Tyr121Val,-1.63,-1.45,1,Y451V +urn:mavedb:00000044-b-2#4836,NA,NA,p.Tyr121Val,-1.27,-1.45,2,Y451V +urn:mavedb:00000044-b-2#4919,NA,NA,p.Tyr123*,-4.6,-4.55,1,Y453 +urn:mavedb:00000044-b-2#4920,NA,NA,p.Tyr123*,-4.51,-4.55,2,Y453 +urn:mavedb:00000044-b-2#4881,NA,NA,p.Tyr123Ala,-0.72,-0.87,1,Y453A +urn:mavedb:00000044-b-2#4882,NA,NA,p.Tyr123Ala,-1.02,-0.87,2,Y453A +urn:mavedb:00000044-b-2#4909,NA,NA,p.Tyr123Arg,0.02,0.01,1,Y453R +urn:mavedb:00000044-b-2#4910,NA,NA,p.Tyr123Arg,0,0.01,2,Y453R +urn:mavedb:00000044-b-2#4903,NA,NA,p.Tyr123Asn,-1.68,-1.52,1,Y453N +urn:mavedb:00000044-b-2#4904,NA,NA,p.Tyr123Asn,-1.37,-1.52,2,Y453N +urn:mavedb:00000044-b-2#4885,NA,NA,p.Tyr123Asp,-2.63,-2.28,1,Y453D +urn:mavedb:00000044-b-2#4886,NA,NA,p.Tyr123Asp,-1.94,-2.28,2,Y453D +urn:mavedb:00000044-b-2#4883,NA,NA,p.Tyr123Cys,-1.22,-1.05,1,Y453C +urn:mavedb:00000044-b-2#4884,NA,NA,p.Tyr123Cys,-0.89,-1.05,2,Y453C +urn:mavedb:00000044-b-2#4907,NA,NA,p.Tyr123Gln,-1.12,-1.21,1,Y453Q +urn:mavedb:00000044-b-2#4908,NA,NA,p.Tyr123Gln,-1.3,-1.21,2,Y453Q +urn:mavedb:00000044-b-2#4887,NA,NA,p.Tyr123Glu,-1.73,-1.92,1,Y453E +urn:mavedb:00000044-b-2#4888,NA,NA,p.Tyr123Glu,-2.11,-1.92,2,Y453E +urn:mavedb:00000044-b-2#4891,NA,NA,p.Tyr123Gly,-2.47,-2.34,1,Y453G +urn:mavedb:00000044-b-2#4892,NA,NA,p.Tyr123Gly,-2.21,-2.34,2,Y453G +urn:mavedb:00000044-b-2#4893,NA,NA,p.Tyr123His,-0.92,-0.58,1,Y453H +urn:mavedb:00000044-b-2#4894,NA,NA,p.Tyr123His,-0.24,-0.58,2,Y453H +urn:mavedb:00000044-b-2#4895,NA,NA,p.Tyr123Ile,-1.84,-1.83,1,Y453I +urn:mavedb:00000044-b-2#4896,NA,NA,p.Tyr123Ile,-1.83,-1.83,2,Y453I +urn:mavedb:00000044-b-2#4899,NA,NA,p.Tyr123Leu,-1.38,-1.37,1,Y453L +urn:mavedb:00000044-b-2#4900,NA,NA,p.Tyr123Leu,-1.36,-1.37,2,Y453L +urn:mavedb:00000044-b-2#4897,NA,NA,p.Tyr123Lys,-0.33,-0.23,1,Y453K +urn:mavedb:00000044-b-2#4898,NA,NA,p.Tyr123Lys,-0.14,-0.23,2,Y453K +urn:mavedb:00000044-b-2#4901,NA,NA,p.Tyr123Met,-0.56,-0.67,1,Y453M +urn:mavedb:00000044-b-2#4902,NA,NA,p.Tyr123Met,-0.78,-0.67,2,Y453M +urn:mavedb:00000044-b-2#4889,NA,NA,p.Tyr123Phe,-0.13,-0.08,1,Y453F +urn:mavedb:00000044-b-2#4890,NA,NA,p.Tyr123Phe,-0.04,-0.08,2,Y453F +urn:mavedb:00000044-b-2#4905,NA,NA,p.Tyr123Pro,-2.6,-2.56,1,Y453P +urn:mavedb:00000044-b-2#4906,NA,NA,p.Tyr123Pro,-2.52,-2.56,2,Y453P +urn:mavedb:00000044-b-2#4911,NA,NA,p.Tyr123Ser,-0.31,-0.34,1,Y453S +urn:mavedb:00000044-b-2#4912,NA,NA,p.Tyr123Ser,-0.37,-0.34,2,Y453S +urn:mavedb:00000044-b-2#4913,NA,NA,p.Tyr123Thr,-1.76,-1.71,1,Y453T +urn:mavedb:00000044-b-2#4914,NA,NA,p.Tyr123Thr,-1.66,-1.71,2,Y453T +urn:mavedb:00000044-b-2#4917,NA,NA,p.Tyr123Trp,-1.4,-1.27,1,Y453W +urn:mavedb:00000044-b-2#4918,NA,NA,p.Tyr123Trp,-1.14,-1.27,2,Y453W +urn:mavedb:00000044-b-2#4915,NA,NA,p.Tyr123Val,-1.01,-1,1,Y453V +urn:mavedb:00000044-b-2#4916,NA,NA,p.Tyr123Val,-1,-1,2,Y453V +urn:mavedb:00000044-b-2#5719,NA,NA,p.Tyr143*,-4.56,-4.55,1,Y473 +urn:mavedb:00000044-b-2#5720,NA,NA,p.Tyr143*,-4.53,-4.55,2,Y473 +urn:mavedb:00000044-b-2#5681,NA,NA,p.Tyr143Ala,-0.75,-0.91,1,Y473A +urn:mavedb:00000044-b-2#5682,NA,NA,p.Tyr143Ala,-1.06,-0.91,2,Y473A +urn:mavedb:00000044-b-2#5709,NA,NA,p.Tyr143Arg,-1.3,-1.25,1,Y473R +urn:mavedb:00000044-b-2#5710,NA,NA,p.Tyr143Arg,-1.21,-1.25,2,Y473R +urn:mavedb:00000044-b-2#5703,NA,NA,p.Tyr143Asn,-0.86,-0.88,1,Y473N +urn:mavedb:00000044-b-2#5704,NA,NA,p.Tyr143Asn,-0.9,-0.88,2,Y473N +urn:mavedb:00000044-b-2#5685,NA,NA,p.Tyr143Asp,-0.66,-0.65,1,Y473D +urn:mavedb:00000044-b-2#5686,NA,NA,p.Tyr143Asp,-0.64,-0.65,2,Y473D +urn:mavedb:00000044-b-2#5683,NA,NA,p.Tyr143Cys,-0.99,-1,1,Y473C +urn:mavedb:00000044-b-2#5684,NA,NA,p.Tyr143Cys,-1,-1,2,Y473C +urn:mavedb:00000044-b-2#5707,NA,NA,p.Tyr143Gln,-0.66,-0.84,1,Y473Q +urn:mavedb:00000044-b-2#5708,NA,NA,p.Tyr143Gln,-1.03,-0.84,2,Y473Q +urn:mavedb:00000044-b-2#5687,NA,NA,p.Tyr143Glu,-0.47,-0.71,1,Y473E +urn:mavedb:00000044-b-2#5688,NA,NA,p.Tyr143Glu,-0.95,-0.71,2,Y473E +urn:mavedb:00000044-b-2#5691,NA,NA,p.Tyr143Gly,-1.13,-1.21,1,Y473G +urn:mavedb:00000044-b-2#5692,NA,NA,p.Tyr143Gly,-1.28,-1.21,2,Y473G +urn:mavedb:00000044-b-2#5693,NA,NA,p.Tyr143His,-0.26,-0.3,1,Y473H +urn:mavedb:00000044-b-2#5694,NA,NA,p.Tyr143His,-0.35,-0.3,2,Y473H +urn:mavedb:00000044-b-2#5695,NA,NA,p.Tyr143Ile,-0.35,-0.44,1,Y473I +urn:mavedb:00000044-b-2#5696,NA,NA,p.Tyr143Ile,-0.52,-0.44,2,Y473I +urn:mavedb:00000044-b-2#5699,NA,NA,p.Tyr143Leu,-0.51,-0.57,1,Y473L +urn:mavedb:00000044-b-2#5700,NA,NA,p.Tyr143Leu,-0.62,-0.57,2,Y473L +urn:mavedb:00000044-b-2#5697,NA,NA,p.Tyr143Lys,-1.26,-1.26,1,Y473K +urn:mavedb:00000044-b-2#5698,NA,NA,p.Tyr143Lys,-1.25,-1.26,2,Y473K +urn:mavedb:00000044-b-2#5701,NA,NA,p.Tyr143Met,-0.58,-0.49,1,Y473M +urn:mavedb:00000044-b-2#5702,NA,NA,p.Tyr143Met,-0.4,-0.49,2,Y473M +urn:mavedb:00000044-b-2#5689,NA,NA,p.Tyr143Phe,-0.16,-0.1,1,Y473F +urn:mavedb:00000044-b-2#5690,NA,NA,p.Tyr143Phe,-0.03,-0.1,2,Y473F +urn:mavedb:00000044-b-2#5705,NA,NA,p.Tyr143Pro,-1.13,-0.97,1,Y473P +urn:mavedb:00000044-b-2#5706,NA,NA,p.Tyr143Pro,-0.8,-0.97,2,Y473P +urn:mavedb:00000044-b-2#5711,NA,NA,p.Tyr143Ser,-0.99,-0.99,1,Y473S +urn:mavedb:00000044-b-2#5712,NA,NA,p.Tyr143Ser,-0.98,-0.99,2,Y473S +urn:mavedb:00000044-b-2#5713,NA,NA,p.Tyr143Thr,-0.86,-0.93,1,Y473T +urn:mavedb:00000044-b-2#5714,NA,NA,p.Tyr143Thr,-1,-0.93,2,Y473T +urn:mavedb:00000044-b-2#5717,NA,NA,p.Tyr143Trp,-0.38,-0.31,1,Y473W +urn:mavedb:00000044-b-2#5718,NA,NA,p.Tyr143Trp,-0.25,-0.31,2,Y473W +urn:mavedb:00000044-b-2#5715,NA,NA,p.Tyr143Val,-0.28,-0.26,1,Y473V +urn:mavedb:00000044-b-2#5716,NA,NA,p.Tyr143Val,-0.24,-0.26,2,Y473V +urn:mavedb:00000044-b-2#6359,NA,NA,p.Tyr159*,-4.58,-4.55,1,Y489 +urn:mavedb:00000044-b-2#6360,NA,NA,p.Tyr159*,-4.51,-4.55,2,Y489 +urn:mavedb:00000044-b-2#6321,NA,NA,p.Tyr159Ala,-0.43,-0.31,1,Y489A +urn:mavedb:00000044-b-2#6322,NA,NA,p.Tyr159Ala,-0.18,-0.31,2,Y489A +urn:mavedb:00000044-b-2#6349,NA,NA,p.Tyr159Arg,-0.08,-0.1,1,Y489R +urn:mavedb:00000044-b-2#6350,NA,NA,p.Tyr159Arg,-0.12,-0.1,2,Y489R +urn:mavedb:00000044-b-2#6343,NA,NA,p.Tyr159Asn,-0.22,-0.16,1,Y489N +urn:mavedb:00000044-b-2#6344,NA,NA,p.Tyr159Asn,-0.11,-0.16,2,Y489N +urn:mavedb:00000044-b-2#6325,NA,NA,p.Tyr159Asp,-0.7,-0.56,1,Y489D +urn:mavedb:00000044-b-2#6326,NA,NA,p.Tyr159Asp,-0.41,-0.56,2,Y489D +urn:mavedb:00000044-b-2#6323,NA,NA,p.Tyr159Cys,-0.22,-0.16,1,Y489C +urn:mavedb:00000044-b-2#6324,NA,NA,p.Tyr159Cys,-0.09,-0.16,2,Y489C +urn:mavedb:00000044-b-2#6347,NA,NA,p.Tyr159Gln,-0.15,-0.18,1,Y489Q +urn:mavedb:00000044-b-2#6348,NA,NA,p.Tyr159Gln,-0.22,-0.18,2,Y489Q +urn:mavedb:00000044-b-2#6327,NA,NA,p.Tyr159Glu,-0.38,-0.28,1,Y489E +urn:mavedb:00000044-b-2#6328,NA,NA,p.Tyr159Glu,-0.17,-0.28,2,Y489E +urn:mavedb:00000044-b-2#6331,NA,NA,p.Tyr159Gly,-0.97,-0.83,1,Y489G +urn:mavedb:00000044-b-2#6332,NA,NA,p.Tyr159Gly,-0.69,-0.83,2,Y489G +urn:mavedb:00000044-b-2#6333,NA,NA,p.Tyr159His,-0.04,0.11,1,Y489H +urn:mavedb:00000044-b-2#6334,NA,NA,p.Tyr159His,0.26,0.11,2,Y489H +urn:mavedb:00000044-b-2#6335,NA,NA,p.Tyr159Ile,-0.01,-0.05,1,Y489I +urn:mavedb:00000044-b-2#6336,NA,NA,p.Tyr159Ile,-0.09,-0.05,2,Y489I +urn:mavedb:00000044-b-2#6339,NA,NA,p.Tyr159Leu,0.01,-0.1,1,Y489L +urn:mavedb:00000044-b-2#6340,NA,NA,p.Tyr159Leu,-0.21,-0.1,2,Y489L +urn:mavedb:00000044-b-2#6337,NA,NA,p.Tyr159Lys,-0.09,-0.04,1,Y489K +urn:mavedb:00000044-b-2#6338,NA,NA,p.Tyr159Lys,0.01,-0.04,2,Y489K +urn:mavedb:00000044-b-2#6341,NA,NA,p.Tyr159Met,-0.12,-0.06,1,Y489M +urn:mavedb:00000044-b-2#6342,NA,NA,p.Tyr159Met,-0.01,-0.06,2,Y489M +urn:mavedb:00000044-b-2#6329,NA,NA,p.Tyr159Phe,-0.21,-0.12,1,Y489F +urn:mavedb:00000044-b-2#6330,NA,NA,p.Tyr159Phe,-0.04,-0.12,2,Y489F +urn:mavedb:00000044-b-2#6345,NA,NA,p.Tyr159Pro,-0.12,-0.36,1,Y489P +urn:mavedb:00000044-b-2#6346,NA,NA,p.Tyr159Pro,-0.6,-0.36,2,Y489P +urn:mavedb:00000044-b-2#6351,NA,NA,p.Tyr159Ser,-0.01,0.06,1,Y489S +urn:mavedb:00000044-b-2#6352,NA,NA,p.Tyr159Ser,0.13,0.06,2,Y489S +urn:mavedb:00000044-b-2#6353,NA,NA,p.Tyr159Thr,0.01,0.04,1,Y489T +urn:mavedb:00000044-b-2#6354,NA,NA,p.Tyr159Thr,0.07,0.04,2,Y489T +urn:mavedb:00000044-b-2#6357,NA,NA,p.Tyr159Trp,-0.06,-0.1,1,Y489W +urn:mavedb:00000044-b-2#6358,NA,NA,p.Tyr159Trp,-0.15,-0.1,2,Y489W +urn:mavedb:00000044-b-2#6355,NA,NA,p.Tyr159Val,-0.13,-0.1,1,Y489V +urn:mavedb:00000044-b-2#6356,NA,NA,p.Tyr159Val,-0.07,-0.1,2,Y489V +urn:mavedb:00000044-b-2#6599,NA,NA,p.Tyr165*,-4.6,-4.55,1,Y495 +urn:mavedb:00000044-b-2#6600,NA,NA,p.Tyr165*,-4.5,-4.55,2,Y495 +urn:mavedb:00000044-b-2#6561,NA,NA,p.Tyr165Ala,-1.76,-1.83,1,Y495A +urn:mavedb:00000044-b-2#6562,NA,NA,p.Tyr165Ala,-1.89,-1.83,2,Y495A +urn:mavedb:00000044-b-2#6589,NA,NA,p.Tyr165Arg,-2.16,-2.08,1,Y495R +urn:mavedb:00000044-b-2#6590,NA,NA,p.Tyr165Arg,-2,-2.08,2,Y495R +urn:mavedb:00000044-b-2#6583,NA,NA,p.Tyr165Asn,-2.16,-2.09,1,Y495N +urn:mavedb:00000044-b-2#6584,NA,NA,p.Tyr165Asn,-2.03,-2.09,2,Y495N +urn:mavedb:00000044-b-2#6565,NA,NA,p.Tyr165Asp,-2.05,-2.15,1,Y495D +urn:mavedb:00000044-b-2#6566,NA,NA,p.Tyr165Asp,-2.26,-2.15,2,Y495D +urn:mavedb:00000044-b-2#6563,NA,NA,p.Tyr165Cys,-2.11,-2.1,1,Y495C +urn:mavedb:00000044-b-2#6564,NA,NA,p.Tyr165Cys,-2.09,-2.1,2,Y495C +urn:mavedb:00000044-b-2#6587,NA,NA,p.Tyr165Gln,-1.59,-1.68,1,Y495Q +urn:mavedb:00000044-b-2#6588,NA,NA,p.Tyr165Gln,-1.78,-1.68,2,Y495Q +urn:mavedb:00000044-b-2#6567,NA,NA,p.Tyr165Glu,-1.54,-1.59,1,Y495E +urn:mavedb:00000044-b-2#6568,NA,NA,p.Tyr165Glu,-1.65,-1.59,2,Y495E +urn:mavedb:00000044-b-2#6571,NA,NA,p.Tyr165Gly,-1.67,-1.85,1,Y495G +urn:mavedb:00000044-b-2#6572,NA,NA,p.Tyr165Gly,-2.04,-1.85,2,Y495G +urn:mavedb:00000044-b-2#6573,NA,NA,p.Tyr165His,-1.15,-1.11,1,Y495H +urn:mavedb:00000044-b-2#6574,NA,NA,p.Tyr165His,-1.07,-1.11,2,Y495H +urn:mavedb:00000044-b-2#6575,NA,NA,p.Tyr165Ile,-2.01,-2.01,1,Y495I +urn:mavedb:00000044-b-2#6576,NA,NA,p.Tyr165Ile,-2,-2.01,2,Y495I +urn:mavedb:00000044-b-2#6579,NA,NA,p.Tyr165Leu,-2.06,-2.13,1,Y495L +urn:mavedb:00000044-b-2#6580,NA,NA,p.Tyr165Leu,-2.2,-2.13,2,Y495L +urn:mavedb:00000044-b-2#6577,NA,NA,p.Tyr165Lys,-1.75,-1.92,1,Y495K +urn:mavedb:00000044-b-2#6578,NA,NA,p.Tyr165Lys,-2.1,-1.92,2,Y495K +urn:mavedb:00000044-b-2#6581,NA,NA,p.Tyr165Met,-1.67,-1.54,1,Y495M +urn:mavedb:00000044-b-2#6582,NA,NA,p.Tyr165Met,-1.4,-1.54,2,Y495M +urn:mavedb:00000044-b-2#6569,NA,NA,p.Tyr165Phe,-1.75,-1.75,1,Y495F +urn:mavedb:00000044-b-2#6570,NA,NA,p.Tyr165Phe,-1.76,-1.75,2,Y495F +urn:mavedb:00000044-b-2#6585,NA,NA,p.Tyr165Pro,-2.02,-2.02,1,Y495P +urn:mavedb:00000044-b-2#6586,NA,NA,p.Tyr165Pro,-2.02,-2.02,2,Y495P +urn:mavedb:00000044-b-2#6591,NA,NA,p.Tyr165Ser,-2.05,-2.02,1,Y495S +urn:mavedb:00000044-b-2#6592,NA,NA,p.Tyr165Ser,-1.99,-2.02,2,Y495S +urn:mavedb:00000044-b-2#6593,NA,NA,p.Tyr165Thr,-2,-2.04,1,Y495T +urn:mavedb:00000044-b-2#6594,NA,NA,p.Tyr165Thr,-2.09,-2.04,2,Y495T +urn:mavedb:00000044-b-2#6597,NA,NA,p.Tyr165Trp,-1.96,-1.87,1,Y495W +urn:mavedb:00000044-b-2#6598,NA,NA,p.Tyr165Trp,-1.78,-1.87,2,Y495W +urn:mavedb:00000044-b-2#6595,NA,NA,p.Tyr165Val,-2.08,-1.91,1,Y495V +urn:mavedb:00000044-b-2#6596,NA,NA,p.Tyr165Val,-1.74,-1.91,2,Y495V +urn:mavedb:00000044-b-2#6999,NA,NA,p.Tyr175*,-4.66,-4.61,1,Y505 +urn:mavedb:00000044-b-2#7000,NA,NA,p.Tyr175*,-4.57,-4.61,2,Y505 +urn:mavedb:00000044-b-2#6961,NA,NA,p.Tyr175Ala,0.12,0.12,1,Y505A +urn:mavedb:00000044-b-2#6962,NA,NA,p.Tyr175Ala,NA,0.12,2,Y505A +urn:mavedb:00000044-b-2#6989,NA,NA,p.Tyr175Arg,0.01,0.02,1,Y505R +urn:mavedb:00000044-b-2#6990,NA,NA,p.Tyr175Arg,0.03,0.02,2,Y505R +urn:mavedb:00000044-b-2#6983,NA,NA,p.Tyr175Asn,0.63,0.56,1,Y505N +urn:mavedb:00000044-b-2#6984,NA,NA,p.Tyr175Asn,0.48,0.56,2,Y505N +urn:mavedb:00000044-b-2#6965,NA,NA,p.Tyr175Asp,0.7,0.41,1,Y505D +urn:mavedb:00000044-b-2#6966,NA,NA,p.Tyr175Asp,0.11,0.41,2,Y505D +urn:mavedb:00000044-b-2#6963,NA,NA,p.Tyr175Cys,0.12,0.12,1,Y505C +urn:mavedb:00000044-b-2#6964,NA,NA,p.Tyr175Cys,0.11,0.12,2,Y505C +urn:mavedb:00000044-b-2#6987,NA,NA,p.Tyr175Gln,0.11,0.21,1,Y505Q +urn:mavedb:00000044-b-2#6988,NA,NA,p.Tyr175Gln,0.32,0.21,2,Y505Q +urn:mavedb:00000044-b-2#6967,NA,NA,p.Tyr175Glu,0.64,0.56,1,Y505E +urn:mavedb:00000044-b-2#6968,NA,NA,p.Tyr175Glu,0.49,0.56,2,Y505E +urn:mavedb:00000044-b-2#6971,NA,NA,p.Tyr175Gly,0.49,0.37,1,Y505G +urn:mavedb:00000044-b-2#6972,NA,NA,p.Tyr175Gly,0.25,0.37,2,Y505G +urn:mavedb:00000044-b-2#6973,NA,NA,p.Tyr175His,0.1,0.16,1,Y505H +urn:mavedb:00000044-b-2#6974,NA,NA,p.Tyr175His,0.22,0.16,2,Y505H +urn:mavedb:00000044-b-2#6975,NA,NA,p.Tyr175Ile,-0.34,-0.42,1,Y505I +urn:mavedb:00000044-b-2#6976,NA,NA,p.Tyr175Ile,-0.51,-0.42,2,Y505I +urn:mavedb:00000044-b-2#6979,NA,NA,p.Tyr175Leu,0.01,0.03,1,Y505L +urn:mavedb:00000044-b-2#6980,NA,NA,p.Tyr175Leu,0.04,0.03,2,Y505L +urn:mavedb:00000044-b-2#6977,NA,NA,p.Tyr175Lys,0.13,0.13,1,Y505K +urn:mavedb:00000044-b-2#6978,NA,NA,p.Tyr175Lys,0.14,0.13,2,Y505K +urn:mavedb:00000044-b-2#6981,NA,NA,p.Tyr175Met,0.21,0.07,1,Y505M +urn:mavedb:00000044-b-2#6982,NA,NA,p.Tyr175Met,-0.07,0.07,2,Y505M +urn:mavedb:00000044-b-2#6969,NA,NA,p.Tyr175Phe,0.01,-0.01,1,Y505F +urn:mavedb:00000044-b-2#6970,NA,NA,p.Tyr175Phe,-0.04,-0.01,2,Y505F +urn:mavedb:00000044-b-2#6985,NA,NA,p.Tyr175Pro,-1.32,-1.09,1,Y505P +urn:mavedb:00000044-b-2#6986,NA,NA,p.Tyr175Pro,-0.86,-1.09,2,Y505P +urn:mavedb:00000044-b-2#6991,NA,NA,p.Tyr175Ser,0.25,0.28,1,Y505S +urn:mavedb:00000044-b-2#6992,NA,NA,p.Tyr175Ser,0.32,0.28,2,Y505S +urn:mavedb:00000044-b-2#6993,NA,NA,p.Tyr175Thr,-0.02,-0.02,1,Y505T +urn:mavedb:00000044-b-2#6994,NA,NA,p.Tyr175Thr,-0.02,-0.02,2,Y505T +urn:mavedb:00000044-b-2#6997,NA,NA,p.Tyr175Trp,-0.03,-0.04,1,Y505W +urn:mavedb:00000044-b-2#6998,NA,NA,p.Tyr175Trp,-0.04,-0.04,2,Y505W +urn:mavedb:00000044-b-2#6995,NA,NA,p.Tyr175Val,-0.26,-0.26,1,Y505V +urn:mavedb:00000044-b-2#6996,NA,NA,p.Tyr175Val,-0.27,-0.26,2,Y505V +urn:mavedb:00000044-b-2#7119,NA,NA,p.Tyr178*,-4.64,-4.58,1,Y508 +urn:mavedb:00000044-b-2#7120,NA,NA,p.Tyr178*,-4.52,-4.58,2,Y508 +urn:mavedb:00000044-b-2#7081,NA,NA,p.Tyr178Ala,-1.04,-0.85,1,Y508A +urn:mavedb:00000044-b-2#7082,NA,NA,p.Tyr178Ala,-0.67,-0.85,2,Y508A +urn:mavedb:00000044-b-2#7109,NA,NA,p.Tyr178Arg,-2.25,-2.26,1,Y508R +urn:mavedb:00000044-b-2#7110,NA,NA,p.Tyr178Arg,-2.28,-2.26,2,Y508R +urn:mavedb:00000044-b-2#7103,NA,NA,p.Tyr178Asn,-0.93,-0.98,1,Y508N +urn:mavedb:00000044-b-2#7104,NA,NA,p.Tyr178Asn,-1.03,-0.98,2,Y508N +urn:mavedb:00000044-b-2#7085,NA,NA,p.Tyr178Asp,-2.26,-2.15,1,Y508D +urn:mavedb:00000044-b-2#7086,NA,NA,p.Tyr178Asp,-2.03,-2.15,2,Y508D +urn:mavedb:00000044-b-2#7083,NA,NA,p.Tyr178Cys,-1.11,-1.02,1,Y508C +urn:mavedb:00000044-b-2#7084,NA,NA,p.Tyr178Cys,-0.93,-1.02,2,Y508C +urn:mavedb:00000044-b-2#7107,NA,NA,p.Tyr178Gln,-1.43,-1.32,1,Y508Q +urn:mavedb:00000044-b-2#7108,NA,NA,p.Tyr178Gln,-1.2,-1.32,2,Y508Q +urn:mavedb:00000044-b-2#7087,NA,NA,p.Tyr178Glu,-2.6,-2.45,1,Y508E +urn:mavedb:00000044-b-2#7088,NA,NA,p.Tyr178Glu,-2.31,-2.45,2,Y508E +urn:mavedb:00000044-b-2#7091,NA,NA,p.Tyr178Gly,-2.86,-2.79,1,Y508G +urn:mavedb:00000044-b-2#7092,NA,NA,p.Tyr178Gly,-2.71,-2.79,2,Y508G +urn:mavedb:00000044-b-2#7093,NA,NA,p.Tyr178His,0.13,0.14,1,Y508H +urn:mavedb:00000044-b-2#7094,NA,NA,p.Tyr178His,0.14,0.14,2,Y508H +urn:mavedb:00000044-b-2#7095,NA,NA,p.Tyr178Ile,-1.44,-1.52,1,Y508I +urn:mavedb:00000044-b-2#7096,NA,NA,p.Tyr178Ile,-1.6,-1.52,2,Y508I +urn:mavedb:00000044-b-2#7099,NA,NA,p.Tyr178Leu,-1.82,-1.72,1,Y508L +urn:mavedb:00000044-b-2#7100,NA,NA,p.Tyr178Leu,-1.63,-1.72,2,Y508L +urn:mavedb:00000044-b-2#7097,NA,NA,p.Tyr178Lys,-2.12,-2.14,1,Y508K +urn:mavedb:00000044-b-2#7098,NA,NA,p.Tyr178Lys,-2.15,-2.14,2,Y508K +urn:mavedb:00000044-b-2#7101,NA,NA,p.Tyr178Met,-0.74,-0.86,1,Y508M +urn:mavedb:00000044-b-2#7102,NA,NA,p.Tyr178Met,-0.99,-0.86,2,Y508M +urn:mavedb:00000044-b-2#7089,NA,NA,p.Tyr178Phe,-0.11,-0.16,1,Y508F +urn:mavedb:00000044-b-2#7090,NA,NA,p.Tyr178Phe,-0.22,-0.16,2,Y508F +urn:mavedb:00000044-b-2#7105,NA,NA,p.Tyr178Pro,-2.82,-2.67,1,Y508P +urn:mavedb:00000044-b-2#7106,NA,NA,p.Tyr178Pro,-2.53,-2.67,2,Y508P +urn:mavedb:00000044-b-2#7111,NA,NA,p.Tyr178Ser,-1.55,-1.43,1,Y508S +urn:mavedb:00000044-b-2#7112,NA,NA,p.Tyr178Ser,-1.31,-1.43,2,Y508S +urn:mavedb:00000044-b-2#7113,NA,NA,p.Tyr178Thr,-1,-1,1,Y508T +urn:mavedb:00000044-b-2#7114,NA,NA,p.Tyr178Thr,-1,-1,2,Y508T +urn:mavedb:00000044-b-2#7117,NA,NA,p.Tyr178Trp,-0.35,-0.45,1,Y508W +urn:mavedb:00000044-b-2#7118,NA,NA,p.Tyr178Trp,-0.55,-0.45,2,Y508W +urn:mavedb:00000044-b-2#7115,NA,NA,p.Tyr178Val,-1.04,-0.98,1,Y508V +urn:mavedb:00000044-b-2#7116,NA,NA,p.Tyr178Val,-0.92,-0.98,2,Y508V +urn:mavedb:00000044-b-2#839,NA,NA,p.Tyr21*,-4.54,-4.6,1,Y351 +urn:mavedb:00000044-b-2#840,NA,NA,p.Tyr21*,-4.65,-4.6,2,Y351 +urn:mavedb:00000044-b-2#801,NA,NA,p.Tyr21Ala,-1.2,-1.47,1,Y351A +urn:mavedb:00000044-b-2#802,NA,NA,p.Tyr21Ala,-1.73,-1.47,2,Y351A +urn:mavedb:00000044-b-2#829,NA,NA,p.Tyr21Arg,-2.9,-2.64,1,Y351R +urn:mavedb:00000044-b-2#830,NA,NA,p.Tyr21Arg,-2.38,-2.64,2,Y351R +urn:mavedb:00000044-b-2#824,NA,NA,p.Tyr21Asn,-2.36,-2.48,2,Y351N +urn:mavedb:00000044-b-2#823,NA,NA,p.Tyr21Asn,-2.6,-2.48,1,Y351N +urn:mavedb:00000044-b-2#805,NA,NA,p.Tyr21Asp,-2.91,-2.86,1,Y351D +urn:mavedb:00000044-b-2#806,NA,NA,p.Tyr21Asp,-2.82,-2.86,2,Y351D +urn:mavedb:00000044-b-2#803,NA,NA,p.Tyr21Cys,-2.05,-2.01,1,Y351C +urn:mavedb:00000044-b-2#804,NA,NA,p.Tyr21Cys,-1.96,-2.01,2,Y351C +urn:mavedb:00000044-b-2#827,NA,NA,p.Tyr21Gln,-1.97,-1.93,1,Y351Q +urn:mavedb:00000044-b-2#828,NA,NA,p.Tyr21Gln,-1.88,-1.93,2,Y351Q +urn:mavedb:00000044-b-2#807,NA,NA,p.Tyr21Glu,-2.18,-2.12,1,Y351E +urn:mavedb:00000044-b-2#808,NA,NA,p.Tyr21Glu,-2.06,-2.12,2,Y351E +urn:mavedb:00000044-b-2#811,NA,NA,p.Tyr21Gly,-2.26,-2.23,1,Y351G +urn:mavedb:00000044-b-2#812,NA,NA,p.Tyr21Gly,-2.2,-2.23,2,Y351G +urn:mavedb:00000044-b-2#813,NA,NA,p.Tyr21His,-0.67,-0.6,1,Y351H +urn:mavedb:00000044-b-2#814,NA,NA,p.Tyr21His,-0.53,-0.6,2,Y351H +urn:mavedb:00000044-b-2#815,NA,NA,p.Tyr21Ile,-2.23,-1.85,1,Y351I +urn:mavedb:00000044-b-2#816,NA,NA,p.Tyr21Ile,-1.46,-1.85,2,Y351I +urn:mavedb:00000044-b-2#819,NA,NA,p.Tyr21Leu,-2.28,-2.24,1,Y351L +urn:mavedb:00000044-b-2#820,NA,NA,p.Tyr21Leu,-2.21,-2.24,2,Y351L +urn:mavedb:00000044-b-2#817,NA,NA,p.Tyr21Lys,-2.37,-2.38,1,Y351K +urn:mavedb:00000044-b-2#818,NA,NA,p.Tyr21Lys,-2.39,-2.38,2,Y351K +urn:mavedb:00000044-b-2#821,NA,NA,p.Tyr21Met,-1.79,-1.87,1,Y351M +urn:mavedb:00000044-b-2#822,NA,NA,p.Tyr21Met,-1.95,-1.87,2,Y351M +urn:mavedb:00000044-b-2#809,NA,NA,p.Tyr21Phe,-0.75,-0.84,1,Y351F +urn:mavedb:00000044-b-2#810,NA,NA,p.Tyr21Phe,-0.93,-0.84,2,Y351F +urn:mavedb:00000044-b-2#825,NA,NA,p.Tyr21Pro,-2.25,-2.42,1,Y351P +urn:mavedb:00000044-b-2#826,NA,NA,p.Tyr21Pro,-2.58,-2.42,2,Y351P +urn:mavedb:00000044-b-2#831,NA,NA,p.Tyr21Ser,-1.83,-1.73,1,Y351S +urn:mavedb:00000044-b-2#832,NA,NA,p.Tyr21Ser,-1.64,-1.73,2,Y351S +urn:mavedb:00000044-b-2#833,NA,NA,p.Tyr21Thr,-1.94,-1.4,1,Y351T +urn:mavedb:00000044-b-2#834,NA,NA,p.Tyr21Thr,-0.85,-1.4,2,Y351T +urn:mavedb:00000044-b-2#837,NA,NA,p.Tyr21Trp,-0.44,-0.65,1,Y351W +urn:mavedb:00000044-b-2#838,NA,NA,p.Tyr21Trp,-0.87,-0.65,2,Y351W +urn:mavedb:00000044-b-2#835,NA,NA,p.Tyr21Val,-1.45,-1.29,1,Y351V +urn:mavedb:00000044-b-2#836,NA,NA,p.Tyr21Val,-1.13,-1.29,2,Y351V +urn:mavedb:00000044-b-2#1399,NA,NA,p.Tyr35*,-4.6,-4.58,1,Y365 +urn:mavedb:00000044-b-2#1400,NA,NA,p.Tyr35*,-4.57,-4.58,2,Y365 +urn:mavedb:00000044-b-2#1361,NA,NA,p.Tyr35Ala,-0.53,-0.57,1,Y365A +urn:mavedb:00000044-b-2#1362,NA,NA,p.Tyr35Ala,-0.61,-0.57,2,Y365A +urn:mavedb:00000044-b-2#1389,NA,NA,p.Tyr35Arg,-1.55,-1.5,1,Y365R +urn:mavedb:00000044-b-2#1390,NA,NA,p.Tyr35Arg,-1.45,-1.5,2,Y365R +urn:mavedb:00000044-b-2#1383,NA,NA,p.Tyr35Asn,-1.61,-1.56,1,Y365N +urn:mavedb:00000044-b-2#1384,NA,NA,p.Tyr35Asn,-1.52,-1.56,2,Y365N +urn:mavedb:00000044-b-2#1365,NA,NA,p.Tyr35Asp,-1.72,-1.63,1,Y365D +urn:mavedb:00000044-b-2#1366,NA,NA,p.Tyr35Asp,-1.55,-1.63,2,Y365D +urn:mavedb:00000044-b-2#1363,NA,NA,p.Tyr35Cys,-0.96,-0.9,1,Y365C +urn:mavedb:00000044-b-2#1364,NA,NA,p.Tyr35Cys,-0.85,-0.9,2,Y365C +urn:mavedb:00000044-b-2#1387,NA,NA,p.Tyr35Gln,-1.44,-1.36,1,Y365Q +urn:mavedb:00000044-b-2#1388,NA,NA,p.Tyr35Gln,-1.29,-1.36,2,Y365Q +urn:mavedb:00000044-b-2#1367,NA,NA,p.Tyr35Glu,-1.45,-1.37,1,Y365E +urn:mavedb:00000044-b-2#1368,NA,NA,p.Tyr35Glu,-1.29,-1.37,2,Y365E +urn:mavedb:00000044-b-2#1371,NA,NA,p.Tyr35Gly,-0.93,-0.98,1,Y365G +urn:mavedb:00000044-b-2#1372,NA,NA,p.Tyr35Gly,-1.03,-0.98,2,Y365G +urn:mavedb:00000044-b-2#1373,NA,NA,p.Tyr35His,-1.54,-1.5,1,Y365H +urn:mavedb:00000044-b-2#1374,NA,NA,p.Tyr35His,-1.46,-1.5,2,Y365H +urn:mavedb:00000044-b-2#1375,NA,NA,p.Tyr35Ile,-0.03,0.03,1,Y365I +urn:mavedb:00000044-b-2#1376,NA,NA,p.Tyr35Ile,0.09,0.03,2,Y365I +urn:mavedb:00000044-b-2#1379,NA,NA,p.Tyr35Leu,0.28,0.3,1,Y365L +urn:mavedb:00000044-b-2#1380,NA,NA,p.Tyr35Leu,0.32,0.3,2,Y365L +urn:mavedb:00000044-b-2#1377,NA,NA,p.Tyr35Lys,-1.48,-1.5,1,Y365K +urn:mavedb:00000044-b-2#1378,NA,NA,p.Tyr35Lys,-1.52,-1.5,2,Y365K +urn:mavedb:00000044-b-2#1381,NA,NA,p.Tyr35Met,0.06,0.1,1,Y365M +urn:mavedb:00000044-b-2#1382,NA,NA,p.Tyr35Met,0.13,0.1,2,Y365M +urn:mavedb:00000044-b-2#1369,NA,NA,p.Tyr35Phe,0.33,0.48,1,Y365F +urn:mavedb:00000044-b-2#1370,NA,NA,p.Tyr35Phe,0.63,0.48,2,Y365F +urn:mavedb:00000044-b-2#1385,NA,NA,p.Tyr35Pro,-1,-1,1,Y365P +urn:mavedb:00000044-b-2#1386,NA,NA,p.Tyr35Pro,-1,-1,2,Y365P +urn:mavedb:00000044-b-2#1391,NA,NA,p.Tyr35Ser,-1.17,-1.09,1,Y365S +urn:mavedb:00000044-b-2#1392,NA,NA,p.Tyr35Ser,-1,-1.09,2,Y365S +urn:mavedb:00000044-b-2#1393,NA,NA,p.Tyr35Thr,-0.94,-0.93,1,Y365T +urn:mavedb:00000044-b-2#1394,NA,NA,p.Tyr35Thr,-0.93,-0.93,2,Y365T +urn:mavedb:00000044-b-2#1397,NA,NA,p.Tyr35Trp,NA,0.99,1,Y365W +urn:mavedb:00000044-b-2#1398,NA,NA,p.Tyr35Trp,0.99,0.99,2,Y365W +urn:mavedb:00000044-b-2#1395,NA,NA,p.Tyr35Val,0.03,0.01,1,Y365V +urn:mavedb:00000044-b-2#1396,NA,NA,p.Tyr35Val,-0.01,0.01,2,Y365V +urn:mavedb:00000044-b-2#1559,NA,NA,p.Tyr39*,-4.63,-4.58,1,Y369 +urn:mavedb:00000044-b-2#1560,NA,NA,p.Tyr39*,-4.53,-4.58,2,Y369 +urn:mavedb:00000044-b-2#1521,NA,NA,p.Tyr39Ala,0.11,0.14,1,Y369A +urn:mavedb:00000044-b-2#1522,NA,NA,p.Tyr39Ala,0.16,0.14,2,Y369A +urn:mavedb:00000044-b-2#1549,NA,NA,p.Tyr39Arg,0.11,0.02,1,Y369R +urn:mavedb:00000044-b-2#1550,NA,NA,p.Tyr39Arg,-0.06,0.02,2,Y369R +urn:mavedb:00000044-b-2#1543,NA,NA,p.Tyr39Asn,0.09,0.09,1,Y369N +urn:mavedb:00000044-b-2#1544,NA,NA,p.Tyr39Asn,0.08,0.09,2,Y369N +urn:mavedb:00000044-b-2#1525,NA,NA,p.Tyr39Asp,-0.48,-0.52,1,Y369D +urn:mavedb:00000044-b-2#1526,NA,NA,p.Tyr39Asp,-0.56,-0.52,2,Y369D +urn:mavedb:00000044-b-2#1523,NA,NA,p.Tyr39Cys,-0.32,-0.37,1,Y369C +urn:mavedb:00000044-b-2#1524,NA,NA,p.Tyr39Cys,-0.42,-0.37,2,Y369C +urn:mavedb:00000044-b-2#1547,NA,NA,p.Tyr39Gln,0.12,0.11,1,Y369Q +urn:mavedb:00000044-b-2#1548,NA,NA,p.Tyr39Gln,0.11,0.11,2,Y369Q +urn:mavedb:00000044-b-2#1527,NA,NA,p.Tyr39Glu,0.18,0.12,1,Y369E +urn:mavedb:00000044-b-2#1528,NA,NA,p.Tyr39Glu,0.06,0.12,2,Y369E +urn:mavedb:00000044-b-2#1531,NA,NA,p.Tyr39Gly,-0.24,-0.23,1,Y369G +urn:mavedb:00000044-b-2#1532,NA,NA,p.Tyr39Gly,-0.22,-0.23,2,Y369G +urn:mavedb:00000044-b-2#1533,NA,NA,p.Tyr39His,-0.05,-0.04,1,Y369H +urn:mavedb:00000044-b-2#1534,NA,NA,p.Tyr39His,-0.02,-0.04,2,Y369H +urn:mavedb:00000044-b-2#1535,NA,NA,p.Tyr39Ile,0.05,0.12,1,Y369I +urn:mavedb:00000044-b-2#1536,NA,NA,p.Tyr39Ile,0.18,0.12,2,Y369I +urn:mavedb:00000044-b-2#1539,NA,NA,p.Tyr39Leu,0.22,0.31,1,Y369L +urn:mavedb:00000044-b-2#1540,NA,NA,p.Tyr39Leu,0.4,0.31,2,Y369L +urn:mavedb:00000044-b-2#1537,NA,NA,p.Tyr39Lys,-0.08,0.07,1,Y369K +urn:mavedb:00000044-b-2#1538,NA,NA,p.Tyr39Lys,0.23,0.07,2,Y369K +urn:mavedb:00000044-b-2#1541,NA,NA,p.Tyr39Met,0.44,0.36,1,Y369M +urn:mavedb:00000044-b-2#1542,NA,NA,p.Tyr39Met,0.28,0.36,2,Y369M +urn:mavedb:00000044-b-2#1529,NA,NA,p.Tyr39Phe,0.19,0.2,1,Y369F +urn:mavedb:00000044-b-2#1530,NA,NA,p.Tyr39Phe,0.21,0.2,2,Y369F +urn:mavedb:00000044-b-2#1545,NA,NA,p.Tyr39Pro,-0.42,-0.37,1,Y369P +urn:mavedb:00000044-b-2#1546,NA,NA,p.Tyr39Pro,-0.33,-0.37,2,Y369P +urn:mavedb:00000044-b-2#1551,NA,NA,p.Tyr39Ser,0.08,0.05,1,Y369S +urn:mavedb:00000044-b-2#1552,NA,NA,p.Tyr39Ser,0.02,0.05,2,Y369S +urn:mavedb:00000044-b-2#1553,NA,NA,p.Tyr39Thr,0.23,0.18,1,Y369T +urn:mavedb:00000044-b-2#1554,NA,NA,p.Tyr39Thr,0.13,0.18,2,Y369T +urn:mavedb:00000044-b-2#1557,NA,NA,p.Tyr39Trp,0.15,0.08,1,Y369W +urn:mavedb:00000044-b-2#1558,NA,NA,p.Tyr39Trp,0,0.08,2,Y369W +urn:mavedb:00000044-b-2#1555,NA,NA,p.Tyr39Val,0.21,0.21,1,Y369V +urn:mavedb:00000044-b-2#1556,NA,NA,p.Tyr39Val,0.2,0.21,2,Y369V +urn:mavedb:00000044-b-2#1999,NA,NA,p.Tyr50*,-4.6,-4.57,1,Y380 +urn:mavedb:00000044-b-2#2000,NA,NA,p.Tyr50*,-4.54,-4.57,2,Y380 +urn:mavedb:00000044-b-2#1961,NA,NA,p.Tyr50Ala,-2.9,-2.81,1,Y380A +urn:mavedb:00000044-b-2#1962,NA,NA,p.Tyr50Ala,-2.72,-2.81,2,Y380A +urn:mavedb:00000044-b-2#1989,NA,NA,p.Tyr50Arg,-2.89,-2.84,1,Y380R +urn:mavedb:00000044-b-2#1990,NA,NA,p.Tyr50Arg,-2.79,-2.84,2,Y380R +urn:mavedb:00000044-b-2#1983,NA,NA,p.Tyr50Asn,-2.89,-2.8,1,Y380N +urn:mavedb:00000044-b-2#1984,NA,NA,p.Tyr50Asn,-2.71,-2.8,2,Y380N +urn:mavedb:00000044-b-2#1965,NA,NA,p.Tyr50Asp,-2.93,-2.84,1,Y380D +urn:mavedb:00000044-b-2#1966,NA,NA,p.Tyr50Asp,-2.75,-2.84,2,Y380D +urn:mavedb:00000044-b-2#1963,NA,NA,p.Tyr50Cys,-2.65,-2.64,1,Y380C +urn:mavedb:00000044-b-2#1964,NA,NA,p.Tyr50Cys,-2.63,-2.64,2,Y380C +urn:mavedb:00000044-b-2#1987,NA,NA,p.Tyr50Gln,-2.7,-2.61,1,Y380Q +urn:mavedb:00000044-b-2#1988,NA,NA,p.Tyr50Gln,-2.53,-2.61,2,Y380Q +urn:mavedb:00000044-b-2#1967,NA,NA,p.Tyr50Glu,-2.97,-2.88,1,Y380E +urn:mavedb:00000044-b-2#1968,NA,NA,p.Tyr50Glu,-2.8,-2.88,2,Y380E +urn:mavedb:00000044-b-2#1971,NA,NA,p.Tyr50Gly,-2.89,-2.78,1,Y380G +urn:mavedb:00000044-b-2#1972,NA,NA,p.Tyr50Gly,-2.67,-2.78,2,Y380G +urn:mavedb:00000044-b-2#1973,NA,NA,p.Tyr50His,-1.88,-1.86,1,Y380H +urn:mavedb:00000044-b-2#1974,NA,NA,p.Tyr50His,-1.85,-1.86,2,Y380H +urn:mavedb:00000044-b-2#1975,NA,NA,p.Tyr50Ile,-2.38,-2.27,1,Y380I +urn:mavedb:00000044-b-2#1976,NA,NA,p.Tyr50Ile,-2.16,-2.27,2,Y380I +urn:mavedb:00000044-b-2#1979,NA,NA,p.Tyr50Leu,-2.73,-2.69,1,Y380L +urn:mavedb:00000044-b-2#1980,NA,NA,p.Tyr50Leu,-2.65,-2.69,2,Y380L +urn:mavedb:00000044-b-2#1977,NA,NA,p.Tyr50Lys,-2.81,-2.79,1,Y380K +urn:mavedb:00000044-b-2#1978,NA,NA,p.Tyr50Lys,-2.77,-2.79,2,Y380K +urn:mavedb:00000044-b-2#1981,NA,NA,p.Tyr50Met,-2.98,-2.74,1,Y380M +urn:mavedb:00000044-b-2#1982,NA,NA,p.Tyr50Met,-2.51,-2.74,2,Y380M +urn:mavedb:00000044-b-2#1969,NA,NA,p.Tyr50Phe,-0.26,-0.45,1,Y380F +urn:mavedb:00000044-b-2#1970,NA,NA,p.Tyr50Phe,-0.63,-0.45,2,Y380F +urn:mavedb:00000044-b-2#1985,NA,NA,p.Tyr50Pro,-2.94,-2.81,1,Y380P +urn:mavedb:00000044-b-2#1986,NA,NA,p.Tyr50Pro,-2.69,-2.81,2,Y380P +urn:mavedb:00000044-b-2#1991,NA,NA,p.Tyr50Ser,-2.67,-2.65,1,Y380S +urn:mavedb:00000044-b-2#1992,NA,NA,p.Tyr50Ser,-2.63,-2.65,2,Y380S +urn:mavedb:00000044-b-2#1993,NA,NA,p.Tyr50Thr,-2.49,-2.46,1,Y380T +urn:mavedb:00000044-b-2#1994,NA,NA,p.Tyr50Thr,-2.42,-2.46,2,Y380T +urn:mavedb:00000044-b-2#1997,NA,NA,p.Tyr50Trp,-0.24,-0.24,1,Y380W +urn:mavedb:00000044-b-2#1998,NA,NA,p.Tyr50Trp,-0.23,-0.24,2,Y380W +urn:mavedb:00000044-b-2#1995,NA,NA,p.Tyr50Val,-2.59,-2.57,1,Y380V +urn:mavedb:00000044-b-2#1996,NA,NA,p.Tyr50Val,-2.56,-2.57,2,Y380V +urn:mavedb:00000044-b-2#2639,NA,NA,p.Tyr66*,-4.54,-4.51,1,Y396 +urn:mavedb:00000044-b-2#2640,NA,NA,p.Tyr66*,-4.49,-4.51,2,Y396 +urn:mavedb:00000044-b-2#2601,NA,NA,p.Tyr66Ala,-1.52,-1.5,1,Y396A +urn:mavedb:00000044-b-2#2602,NA,NA,p.Tyr66Ala,-1.47,-1.5,2,Y396A +urn:mavedb:00000044-b-2#2629,NA,NA,p.Tyr66Arg,-1.84,-1.81,1,Y396R +urn:mavedb:00000044-b-2#2630,NA,NA,p.Tyr66Arg,-1.78,-1.81,2,Y396R +urn:mavedb:00000044-b-2#2623,NA,NA,p.Tyr66Asn,-0.21,-0.31,1,Y396N +urn:mavedb:00000044-b-2#2624,NA,NA,p.Tyr66Asn,-0.41,-0.31,2,Y396N +urn:mavedb:00000044-b-2#2605,NA,NA,p.Tyr66Asp,-1.23,-1.29,1,Y396D +urn:mavedb:00000044-b-2#2606,NA,NA,p.Tyr66Asp,-1.35,-1.29,2,Y396D +urn:mavedb:00000044-b-2#2603,NA,NA,p.Tyr66Cys,-0.93,-0.98,1,Y396C +urn:mavedb:00000044-b-2#2604,NA,NA,p.Tyr66Cys,-1.03,-0.98,2,Y396C +urn:mavedb:00000044-b-2#2627,NA,NA,p.Tyr66Gln,-0.72,-0.98,1,Y396Q +urn:mavedb:00000044-b-2#2628,NA,NA,p.Tyr66Gln,-1.25,-0.98,2,Y396Q +urn:mavedb:00000044-b-2#2607,NA,NA,p.Tyr66Glu,-1.8,-1.78,1,Y396E +urn:mavedb:00000044-b-2#2608,NA,NA,p.Tyr66Glu,-1.77,-1.78,2,Y396E +urn:mavedb:00000044-b-2#2611,NA,NA,p.Tyr66Gly,-2.64,-2.44,1,Y396G +urn:mavedb:00000044-b-2#2612,NA,NA,p.Tyr66Gly,-2.24,-2.44,2,Y396G +urn:mavedb:00000044-b-2#2613,NA,NA,p.Tyr66His,-0.94,-0.82,1,Y396H +urn:mavedb:00000044-b-2#2614,NA,NA,p.Tyr66His,-0.7,-0.82,2,Y396H +urn:mavedb:00000044-b-2#2615,NA,NA,p.Tyr66Ile,-0.32,-0.24,1,Y396I +urn:mavedb:00000044-b-2#2616,NA,NA,p.Tyr66Ile,-0.15,-0.24,2,Y396I +urn:mavedb:00000044-b-2#2619,NA,NA,p.Tyr66Leu,-0.33,-0.43,1,Y396L +urn:mavedb:00000044-b-2#2620,NA,NA,p.Tyr66Leu,-0.53,-0.43,2,Y396L +urn:mavedb:00000044-b-2#2617,NA,NA,p.Tyr66Lys,-1.43,-1.53,1,Y396K +urn:mavedb:00000044-b-2#2618,NA,NA,p.Tyr66Lys,-1.64,-1.53,2,Y396K +urn:mavedb:00000044-b-2#2621,NA,NA,p.Tyr66Met,-0.78,-0.6,1,Y396M +urn:mavedb:00000044-b-2#2622,NA,NA,p.Tyr66Met,-0.43,-0.6,2,Y396M +urn:mavedb:00000044-b-2#2609,NA,NA,p.Tyr66Phe,-0.19,-0.23,1,Y396F +urn:mavedb:00000044-b-2#2610,NA,NA,p.Tyr66Phe,-0.28,-0.23,2,Y396F +urn:mavedb:00000044-b-2#2625,NA,NA,p.Tyr66Pro,-2.54,-2.52,1,Y396P +urn:mavedb:00000044-b-2#2626,NA,NA,p.Tyr66Pro,-2.49,-2.52,2,Y396P +urn:mavedb:00000044-b-2#2631,NA,NA,p.Tyr66Ser,-0.96,-0.95,1,Y396S +urn:mavedb:00000044-b-2#2632,NA,NA,p.Tyr66Ser,-0.94,-0.95,2,Y396S +urn:mavedb:00000044-b-2#2633,NA,NA,p.Tyr66Thr,-0.11,-0.12,1,Y396T +urn:mavedb:00000044-b-2#2634,NA,NA,p.Tyr66Thr,-0.12,-0.12,2,Y396T +urn:mavedb:00000044-b-2#2637,NA,NA,p.Tyr66Trp,-0.07,-0.18,1,Y396W +urn:mavedb:00000044-b-2#2638,NA,NA,p.Tyr66Trp,-0.28,-0.18,2,Y396W +urn:mavedb:00000044-b-2#2635,NA,NA,p.Tyr66Val,-0.35,-0.28,1,Y396V +urn:mavedb:00000044-b-2#2636,NA,NA,p.Tyr66Val,-0.21,-0.28,2,Y396V +urn:mavedb:00000044-b-2#3639,NA,NA,p.Tyr91*,-4.6,-4.56,1,Y421 +urn:mavedb:00000044-b-2#3640,NA,NA,p.Tyr91*,-4.52,-4.56,2,Y421 +urn:mavedb:00000044-b-2#3601,NA,NA,p.Tyr91Ala,-1.88,-1.75,1,Y421A +urn:mavedb:00000044-b-2#3602,NA,NA,p.Tyr91Ala,-1.62,-1.75,2,Y421A +urn:mavedb:00000044-b-2#3629,NA,NA,p.Tyr91Arg,-2.03,-2.02,1,Y421R +urn:mavedb:00000044-b-2#3630,NA,NA,p.Tyr91Arg,-2.01,-2.02,2,Y421R +urn:mavedb:00000044-b-2#3623,NA,NA,p.Tyr91Asn,-1.13,-1.16,1,Y421N +urn:mavedb:00000044-b-2#3624,NA,NA,p.Tyr91Asn,-1.18,-1.16,2,Y421N +urn:mavedb:00000044-b-2#3605,NA,NA,p.Tyr91Asp,-2.37,-2.4,1,Y421D +urn:mavedb:00000044-b-2#3606,NA,NA,p.Tyr91Asp,-2.42,-2.4,2,Y421D +urn:mavedb:00000044-b-2#3603,NA,NA,p.Tyr91Cys,-1.33,-1.32,1,Y421C +urn:mavedb:00000044-b-2#3604,NA,NA,p.Tyr91Cys,-1.31,-1.32,2,Y421C +urn:mavedb:00000044-b-2#3627,NA,NA,p.Tyr91Gln,-1.89,-2,1,Y421Q +urn:mavedb:00000044-b-2#3628,NA,NA,p.Tyr91Gln,-2.11,-2,2,Y421Q +urn:mavedb:00000044-b-2#3607,NA,NA,p.Tyr91Glu,-2.28,-2.23,1,Y421E +urn:mavedb:00000044-b-2#3608,NA,NA,p.Tyr91Glu,-2.18,-2.23,2,Y421E +urn:mavedb:00000044-b-2#3611,NA,NA,p.Tyr91Gly,-2.25,-2.19,1,Y421G +urn:mavedb:00000044-b-2#3612,NA,NA,p.Tyr91Gly,-2.14,-2.19,2,Y421G +urn:mavedb:00000044-b-2#3613,NA,NA,p.Tyr91His,-1,-1.11,1,Y421H +urn:mavedb:00000044-b-2#3614,NA,NA,p.Tyr91His,-1.22,-1.11,2,Y421H +urn:mavedb:00000044-b-2#3615,NA,NA,p.Tyr91Ile,-1.18,-1.28,1,Y421I +urn:mavedb:00000044-b-2#3616,NA,NA,p.Tyr91Ile,-1.39,-1.28,2,Y421I +urn:mavedb:00000044-b-2#3619,NA,NA,p.Tyr91Leu,-0.71,-0.64,1,Y421L +urn:mavedb:00000044-b-2#3620,NA,NA,p.Tyr91Leu,-0.56,-0.64,2,Y421L +urn:mavedb:00000044-b-2#3617,NA,NA,p.Tyr91Lys,-1.55,-1.54,1,Y421K +urn:mavedb:00000044-b-2#3618,NA,NA,p.Tyr91Lys,-1.54,-1.54,2,Y421K +urn:mavedb:00000044-b-2#3621,NA,NA,p.Tyr91Met,-1.1,-0.98,1,Y421M +urn:mavedb:00000044-b-2#3622,NA,NA,p.Tyr91Met,-0.85,-0.98,2,Y421M +urn:mavedb:00000044-b-2#3609,NA,NA,p.Tyr91Phe,-0.03,-0.05,1,Y421F +urn:mavedb:00000044-b-2#3610,NA,NA,p.Tyr91Phe,-0.06,-0.05,2,Y421F +urn:mavedb:00000044-b-2#3625,NA,NA,p.Tyr91Pro,-2.59,-2.57,1,Y421P +urn:mavedb:00000044-b-2#3626,NA,NA,p.Tyr91Pro,-2.55,-2.57,2,Y421P +urn:mavedb:00000044-b-2#3631,NA,NA,p.Tyr91Ser,-1.92,-1.87,1,Y421S +urn:mavedb:00000044-b-2#3632,NA,NA,p.Tyr91Ser,-1.82,-1.87,2,Y421S +urn:mavedb:00000044-b-2#3633,NA,NA,p.Tyr91Thr,-2.23,-2.2,1,Y421T +urn:mavedb:00000044-b-2#3634,NA,NA,p.Tyr91Thr,-2.17,-2.2,2,Y421T +urn:mavedb:00000044-b-2#3637,NA,NA,p.Tyr91Trp,-0.68,-0.72,1,Y421W +urn:mavedb:00000044-b-2#3638,NA,NA,p.Tyr91Trp,-0.75,-0.72,2,Y421W +urn:mavedb:00000044-b-2#3635,NA,NA,p.Tyr91Val,-1.84,-1.78,1,Y421V +urn:mavedb:00000044-b-2#3636,NA,NA,p.Tyr91Val,-1.73,-1.78,2,Y421V +urn:mavedb:00000044-b-2#3719,NA,NA,p.Tyr93*,-4.57,-4.56,1,Y423 +urn:mavedb:00000044-b-2#3720,NA,NA,p.Tyr93*,-4.56,-4.56,2,Y423 +urn:mavedb:00000044-b-2#3681,NA,NA,p.Tyr93Ala,-2.68,-2.68,1,Y423A +urn:mavedb:00000044-b-2#3682,NA,NA,p.Tyr93Ala,-2.69,-2.68,2,Y423A +urn:mavedb:00000044-b-2#3709,NA,NA,p.Tyr93Arg,-2.9,-2.84,1,Y423R +urn:mavedb:00000044-b-2#3710,NA,NA,p.Tyr93Arg,-2.78,-2.84,2,Y423R +urn:mavedb:00000044-b-2#3703,NA,NA,p.Tyr93Asn,-2.64,-2.65,1,Y423N +urn:mavedb:00000044-b-2#3704,NA,NA,p.Tyr93Asn,-2.67,-2.65,2,Y423N +urn:mavedb:00000044-b-2#3685,NA,NA,p.Tyr93Asp,-2.55,-2.61,1,Y423D +urn:mavedb:00000044-b-2#3686,NA,NA,p.Tyr93Asp,-2.67,-2.61,2,Y423D +urn:mavedb:00000044-b-2#3683,NA,NA,p.Tyr93Cys,-2.6,-2.6,1,Y423C +urn:mavedb:00000044-b-2#3684,NA,NA,p.Tyr93Cys,-2.59,-2.6,2,Y423C +urn:mavedb:00000044-b-2#3707,NA,NA,p.Tyr93Gln,-2.87,-2.74,1,Y423Q +urn:mavedb:00000044-b-2#3708,NA,NA,p.Tyr93Gln,-2.61,-2.74,2,Y423Q +urn:mavedb:00000044-b-2#3687,NA,NA,p.Tyr93Glu,-2.7,-2.73,1,Y423E +urn:mavedb:00000044-b-2#3688,NA,NA,p.Tyr93Glu,-2.76,-2.73,2,Y423E +urn:mavedb:00000044-b-2#3691,NA,NA,p.Tyr93Gly,-2.84,-2.78,1,Y423G +urn:mavedb:00000044-b-2#3692,NA,NA,p.Tyr93Gly,-2.72,-2.78,2,Y423G +urn:mavedb:00000044-b-2#3693,NA,NA,p.Tyr93His,-2.82,-2.76,1,Y423H +urn:mavedb:00000044-b-2#3694,NA,NA,p.Tyr93His,-2.7,-2.76,2,Y423H +urn:mavedb:00000044-b-2#3695,NA,NA,p.Tyr93Ile,-2.67,-2.64,1,Y423I +urn:mavedb:00000044-b-2#3696,NA,NA,p.Tyr93Ile,-2.61,-2.64,2,Y423I +urn:mavedb:00000044-b-2#3699,NA,NA,p.Tyr93Leu,-2.59,-2.59,1,Y423L +urn:mavedb:00000044-b-2#3700,NA,NA,p.Tyr93Leu,-2.6,-2.59,2,Y423L +urn:mavedb:00000044-b-2#3697,NA,NA,p.Tyr93Lys,-2.89,-2.77,1,Y423K +urn:mavedb:00000044-b-2#3698,NA,NA,p.Tyr93Lys,-2.65,-2.77,2,Y423K +urn:mavedb:00000044-b-2#3701,NA,NA,p.Tyr93Met,-2.73,-2.67,1,Y423M +urn:mavedb:00000044-b-2#3702,NA,NA,p.Tyr93Met,-2.61,-2.67,2,Y423M +urn:mavedb:00000044-b-2#3689,NA,NA,p.Tyr93Phe,-1.92,-1.85,1,Y423F +urn:mavedb:00000044-b-2#3690,NA,NA,p.Tyr93Phe,-1.79,-1.85,2,Y423F +urn:mavedb:00000044-b-2#3705,NA,NA,p.Tyr93Pro,-2.78,-2.75,1,Y423P +urn:mavedb:00000044-b-2#3706,NA,NA,p.Tyr93Pro,-2.72,-2.75,2,Y423P +urn:mavedb:00000044-b-2#3711,NA,NA,p.Tyr93Ser,-2.78,-2.76,1,Y423S +urn:mavedb:00000044-b-2#3712,NA,NA,p.Tyr93Ser,-2.74,-2.76,2,Y423S +urn:mavedb:00000044-b-2#3713,NA,NA,p.Tyr93Thr,-2.88,-2.81,1,Y423T +urn:mavedb:00000044-b-2#3714,NA,NA,p.Tyr93Thr,-2.74,-2.81,2,Y423T +urn:mavedb:00000044-b-2#3717,NA,NA,p.Tyr93Trp,-2.87,-2.76,1,Y423W +urn:mavedb:00000044-b-2#3718,NA,NA,p.Tyr93Trp,-2.66,-2.76,2,Y423W +urn:mavedb:00000044-b-2#3715,NA,NA,p.Tyr93Val,-2.72,-2.7,1,Y423V +urn:mavedb:00000044-b-2#3716,NA,NA,p.Tyr93Val,-2.69,-2.7,2,Y423V +urn:mavedb:00000044-b-2#4119,NA,NA,p.Val103*,-4.62,-4.57,1,V433 +urn:mavedb:00000044-b-2#4120,NA,NA,p.Val103*,-4.52,-4.57,2,V433 +urn:mavedb:00000044-b-2#4081,NA,NA,p.Val103Ala,-3.02,-2.96,1,V433A +urn:mavedb:00000044-b-2#4082,NA,NA,p.Val103Ala,-2.89,-2.96,2,V433A +urn:mavedb:00000044-b-2#4109,NA,NA,p.Val103Arg,-3.16,-3.12,1,V433R +urn:mavedb:00000044-b-2#4110,NA,NA,p.Val103Arg,-3.08,-3.12,2,V433R +urn:mavedb:00000044-b-2#4103,NA,NA,p.Val103Asn,-3.29,-3.2,1,V433N +urn:mavedb:00000044-b-2#4104,NA,NA,p.Val103Asn,-3.11,-3.2,2,V433N +urn:mavedb:00000044-b-2#4085,NA,NA,p.Val103Asp,-3.19,-3.1,1,V433D +urn:mavedb:00000044-b-2#4086,NA,NA,p.Val103Asp,-3.01,-3.1,2,V433D +urn:mavedb:00000044-b-2#4083,NA,NA,p.Val103Cys,-2.55,-2.48,1,V433C +urn:mavedb:00000044-b-2#4084,NA,NA,p.Val103Cys,-2.41,-2.48,2,V433C +urn:mavedb:00000044-b-2#4107,NA,NA,p.Val103Gln,-3.19,-3.11,1,V433Q +urn:mavedb:00000044-b-2#4108,NA,NA,p.Val103Gln,-3.03,-3.11,2,V433Q +urn:mavedb:00000044-b-2#4087,NA,NA,p.Val103Glu,-3.06,-3.05,1,V433E +urn:mavedb:00000044-b-2#4088,NA,NA,p.Val103Glu,-3.05,-3.05,2,V433E +urn:mavedb:00000044-b-2#4091,NA,NA,p.Val103Gly,-3.17,-3.07,1,V433G +urn:mavedb:00000044-b-2#4092,NA,NA,p.Val103Gly,-2.98,-3.07,2,V433G +urn:mavedb:00000044-b-2#4093,NA,NA,p.Val103His,-3.25,-3.14,1,V433H +urn:mavedb:00000044-b-2#4094,NA,NA,p.Val103His,-3.04,-3.14,2,V433H +urn:mavedb:00000044-b-2#4095,NA,NA,p.Val103Ile,-0.75,-0.73,1,V433I +urn:mavedb:00000044-b-2#4096,NA,NA,p.Val103Ile,-0.71,-0.73,2,V433I +urn:mavedb:00000044-b-2#4099,NA,NA,p.Val103Leu,-2.69,-2.66,1,V433L +urn:mavedb:00000044-b-2#4100,NA,NA,p.Val103Leu,-2.62,-2.66,2,V433L +urn:mavedb:00000044-b-2#4097,NA,NA,p.Val103Lys,-3.2,-3.15,1,V433K +urn:mavedb:00000044-b-2#4098,NA,NA,p.Val103Lys,-3.11,-3.15,2,V433K +urn:mavedb:00000044-b-2#4101,NA,NA,p.Val103Met,-2.75,-2.76,1,V433M +urn:mavedb:00000044-b-2#4102,NA,NA,p.Val103Met,-2.76,-2.76,2,V433M +urn:mavedb:00000044-b-2#4089,NA,NA,p.Val103Phe,-2.89,-2.85,1,V433F +urn:mavedb:00000044-b-2#4090,NA,NA,p.Val103Phe,-2.8,-2.85,2,V433F +urn:mavedb:00000044-b-2#4105,NA,NA,p.Val103Pro,-3.31,-3.28,1,V433P +urn:mavedb:00000044-b-2#4106,NA,NA,p.Val103Pro,-3.25,-3.28,2,V433P +urn:mavedb:00000044-b-2#4111,NA,NA,p.Val103Ser,-3.19,-3.12,1,V433S +urn:mavedb:00000044-b-2#4112,NA,NA,p.Val103Ser,-3.06,-3.12,2,V433S +urn:mavedb:00000044-b-2#4113,NA,NA,p.Val103Thr,-2.48,-2.69,1,V433T +urn:mavedb:00000044-b-2#4114,NA,NA,p.Val103Thr,-2.9,-2.69,2,V433T +urn:mavedb:00000044-b-2#4115,NA,NA,p.Val103Trp,-2.93,-2.9,1,V433W +urn:mavedb:00000044-b-2#4116,NA,NA,p.Val103Trp,-2.86,-2.9,2,V433W +urn:mavedb:00000044-b-2#4117,NA,NA,p.Val103Tyr,-2.97,-2.91,1,V433Y +urn:mavedb:00000044-b-2#4118,NA,NA,p.Val103Tyr,-2.84,-2.91,2,V433Y +urn:mavedb:00000044-b-2#439,NA,NA,p.Val11*,-4.11,-4.02,1,V341 +urn:mavedb:00000044-b-2#440,NA,NA,p.Val11*,-3.92,-4.02,2,V341 +urn:mavedb:00000044-b-2#4599,NA,NA,p.Val115*,-4.64,-4.58,1,V445 +urn:mavedb:00000044-b-2#4600,NA,NA,p.Val115*,-4.51,-4.58,2,V445 +urn:mavedb:00000044-b-2#4561,NA,NA,p.Val115Ala,0.02,-0.08,1,V445A +urn:mavedb:00000044-b-2#4562,NA,NA,p.Val115Ala,-0.17,-0.08,2,V445A +urn:mavedb:00000044-b-2#4589,NA,NA,p.Val115Arg,-0.25,-0.26,1,V445R +urn:mavedb:00000044-b-2#4590,NA,NA,p.Val115Arg,-0.27,-0.26,2,V445R +urn:mavedb:00000044-b-2#4583,NA,NA,p.Val115Asn,0.14,0.03,1,V445N +urn:mavedb:00000044-b-2#4584,NA,NA,p.Val115Asn,-0.08,0.03,2,V445N +urn:mavedb:00000044-b-2#4565,NA,NA,p.Val115Asp,0.1,0.1,1,V445D +urn:mavedb:00000044-b-2#4566,NA,NA,p.Val115Asp,0.11,0.1,2,V445D +urn:mavedb:00000044-b-2#4563,NA,NA,p.Val115Cys,-0.31,-0.35,1,V445C +urn:mavedb:00000044-b-2#4564,NA,NA,p.Val115Cys,-0.38,-0.35,2,V445C +urn:mavedb:00000044-b-2#4587,NA,NA,p.Val115Gln,-0.13,-0.05,1,V445Q +urn:mavedb:00000044-b-2#4588,NA,NA,p.Val115Gln,0.03,-0.05,2,V445Q +urn:mavedb:00000044-b-2#4568,NA,NA,p.Val115Glu,0.09,0.06,2,V445E +urn:mavedb:00000044-b-2#4567,NA,NA,p.Val115Glu,0.04,0.06,1,V445E +urn:mavedb:00000044-b-2#4571,NA,NA,p.Val115Gly,-0.22,-0.15,1,V445G +urn:mavedb:00000044-b-2#4572,NA,NA,p.Val115Gly,-0.08,-0.15,2,V445G +urn:mavedb:00000044-b-2#4573,NA,NA,p.Val115His,-0.18,-0.13,1,V445H +urn:mavedb:00000044-b-2#4574,NA,NA,p.Val115His,-0.08,-0.13,2,V445H +urn:mavedb:00000044-b-2#4575,NA,NA,p.Val115Ile,0.08,-0.04,1,V445I +urn:mavedb:00000044-b-2#4576,NA,NA,p.Val115Ile,-0.16,-0.04,2,V445I +urn:mavedb:00000044-b-2#4579,NA,NA,p.Val115Leu,-0.19,-0.15,1,V445L +urn:mavedb:00000044-b-2#4580,NA,NA,p.Val115Leu,-0.1,-0.15,2,V445L +urn:mavedb:00000044-b-2#4577,NA,NA,p.Val115Lys,0.08,0.03,1,V445K +urn:mavedb:00000044-b-2#4578,NA,NA,p.Val115Lys,-0.02,0.03,2,V445K +urn:mavedb:00000044-b-2#4581,NA,NA,p.Val115Met,-0.17,-0.08,1,V445M +urn:mavedb:00000044-b-2#4582,NA,NA,p.Val115Met,0.01,-0.08,2,V445M +urn:mavedb:00000044-b-2#4569,NA,NA,p.Val115Phe,-0.19,-0.24,1,V445F +urn:mavedb:00000044-b-2#4570,NA,NA,p.Val115Phe,-0.29,-0.24,2,V445F +urn:mavedb:00000044-b-2#4585,NA,NA,p.Val115Pro,0.14,0.05,1,V445P +urn:mavedb:00000044-b-2#4586,NA,NA,p.Val115Pro,-0.05,0.05,2,V445P +urn:mavedb:00000044-b-2#4591,NA,NA,p.Val115Ser,-0.12,-0.12,1,V445S +urn:mavedb:00000044-b-2#4592,NA,NA,p.Val115Ser,-0.12,-0.12,2,V445S +urn:mavedb:00000044-b-2#4593,NA,NA,p.Val115Thr,-0.11,-0.09,1,V445T +urn:mavedb:00000044-b-2#4594,NA,NA,p.Val115Thr,-0.07,-0.09,2,V445T +urn:mavedb:00000044-b-2#4595,NA,NA,p.Val115Trp,-0.47,-0.36,1,V445W +urn:mavedb:00000044-b-2#4596,NA,NA,p.Val115Trp,-0.25,-0.36,2,V445W +urn:mavedb:00000044-b-2#4597,NA,NA,p.Val115Tyr,-0.25,-0.24,1,V445Y +urn:mavedb:00000044-b-2#4598,NA,NA,p.Val115Tyr,-0.22,-0.24,2,V445Y +urn:mavedb:00000044-b-2#401,NA,NA,p.Val11Ala,-2.1,-1.98,1,V341A +urn:mavedb:00000044-b-2#402,NA,NA,p.Val11Ala,-1.85,-1.98,2,V341A +urn:mavedb:00000044-b-2#429,NA,NA,p.Val11Arg,-2.26,-2.22,1,V341R +urn:mavedb:00000044-b-2#430,NA,NA,p.Val11Arg,-2.17,-2.22,2,V341R +urn:mavedb:00000044-b-2#423,NA,NA,p.Val11Asn,-2.25,-2.17,1,V341N +urn:mavedb:00000044-b-2#424,NA,NA,p.Val11Asn,-2.09,-2.17,2,V341N +urn:mavedb:00000044-b-2#405,NA,NA,p.Val11Asp,-2.16,-2.21,1,V341D +urn:mavedb:00000044-b-2#406,NA,NA,p.Val11Asp,-2.26,-2.21,2,V341D +urn:mavedb:00000044-b-2#403,NA,NA,p.Val11Cys,-1.93,-1.94,1,V341C +urn:mavedb:00000044-b-2#404,NA,NA,p.Val11Cys,-1.94,-1.94,2,V341C +urn:mavedb:00000044-b-2#427,NA,NA,p.Val11Gln,-2.02,-1.99,1,V341Q +urn:mavedb:00000044-b-2#428,NA,NA,p.Val11Gln,-1.96,-1.99,2,V341Q +urn:mavedb:00000044-b-2#407,NA,NA,p.Val11Glu,-2.25,-2.22,1,V341E +urn:mavedb:00000044-b-2#408,NA,NA,p.Val11Glu,-2.19,-2.22,2,V341E +urn:mavedb:00000044-b-2#411,NA,NA,p.Val11Gly,-2.36,-2.3,1,V341G +urn:mavedb:00000044-b-2#412,NA,NA,p.Val11Gly,-2.25,-2.3,2,V341G +urn:mavedb:00000044-b-2#413,NA,NA,p.Val11His,-2.01,-2.01,1,V341H +urn:mavedb:00000044-b-2#414,NA,NA,p.Val11His,-2,-2.01,2,V341H +urn:mavedb:00000044-b-2#415,NA,NA,p.Val11Ile,0.09,0.21,1,V341I +urn:mavedb:00000044-b-2#416,NA,NA,p.Val11Ile,0.33,0.21,2,V341I +urn:mavedb:00000044-b-2#419,NA,NA,p.Val11Leu,-0.39,-0.43,1,V341L +urn:mavedb:00000044-b-2#420,NA,NA,p.Val11Leu,-0.47,-0.43,2,V341L +urn:mavedb:00000044-b-2#417,NA,NA,p.Val11Lys,-2.24,-2.23,1,V341K +urn:mavedb:00000044-b-2#418,NA,NA,p.Val11Lys,-2.23,-2.23,2,V341K +urn:mavedb:00000044-b-2#421,NA,NA,p.Val11Met,-1.12,-1.1,1,V341M +urn:mavedb:00000044-b-2#422,NA,NA,p.Val11Met,-1.08,-1.1,2,V341M +urn:mavedb:00000044-b-2#409,NA,NA,p.Val11Phe,-1.1,-1.06,1,V341F +urn:mavedb:00000044-b-2#410,NA,NA,p.Val11Phe,-1.03,-1.06,2,V341F +urn:mavedb:00000044-b-2#425,NA,NA,p.Val11Pro,-2.14,-1.98,1,V341P +urn:mavedb:00000044-b-2#426,NA,NA,p.Val11Pro,-1.82,-1.98,2,V341P +urn:mavedb:00000044-b-2#431,NA,NA,p.Val11Ser,-2.14,-2.18,1,V341S +urn:mavedb:00000044-b-2#432,NA,NA,p.Val11Ser,-2.22,-2.18,2,V341S +urn:mavedb:00000044-b-2#433,NA,NA,p.Val11Thr,-1.49,-1.5,1,V341T +urn:mavedb:00000044-b-2#434,NA,NA,p.Val11Thr,-1.52,-1.5,2,V341T +urn:mavedb:00000044-b-2#435,NA,NA,p.Val11Trp,-0.97,-1.18,1,V341W +urn:mavedb:00000044-b-2#436,NA,NA,p.Val11Trp,-1.38,-1.18,2,V341W +urn:mavedb:00000044-b-2#437,NA,NA,p.Val11Tyr,-1.34,-1.29,1,V341Y +urn:mavedb:00000044-b-2#438,NA,NA,p.Val11Tyr,-1.25,-1.29,2,V341Y +urn:mavedb:00000044-b-2#6119,NA,NA,p.Val153*,-4.61,-4.58,1,V483 +urn:mavedb:00000044-b-2#6120,NA,NA,p.Val153*,-4.54,-4.58,2,V483 +urn:mavedb:00000044-b-2#6081,NA,NA,p.Val153Ala,0.01,0.09,1,V483A +urn:mavedb:00000044-b-2#6082,NA,NA,p.Val153Ala,0.17,0.09,2,V483A +urn:mavedb:00000044-b-2#6109,NA,NA,p.Val153Arg,-0.07,-0.06,1,V483R +urn:mavedb:00000044-b-2#6110,NA,NA,p.Val153Arg,-0.06,-0.06,2,V483R +urn:mavedb:00000044-b-2#6103,NA,NA,p.Val153Asn,-0.19,-0.06,1,V483N +urn:mavedb:00000044-b-2#6104,NA,NA,p.Val153Asn,0.07,-0.06,2,V483N +urn:mavedb:00000044-b-2#6085,NA,NA,p.Val153Asp,-0.09,-0.1,1,V483D +urn:mavedb:00000044-b-2#6086,NA,NA,p.Val153Asp,-0.11,-0.1,2,V483D +urn:mavedb:00000044-b-2#6083,NA,NA,p.Val153Cys,-0.29,-0.22,1,V483C +urn:mavedb:00000044-b-2#6084,NA,NA,p.Val153Cys,-0.16,-0.22,2,V483C +urn:mavedb:00000044-b-2#6107,NA,NA,p.Val153Gln,0.05,0.08,1,V483Q +urn:mavedb:00000044-b-2#6108,NA,NA,p.Val153Gln,0.12,0.08,2,V483Q +urn:mavedb:00000044-b-2#6087,NA,NA,p.Val153Glu,0,-0.01,1,V483E +urn:mavedb:00000044-b-2#6088,NA,NA,p.Val153Glu,-0.03,-0.01,2,V483E +urn:mavedb:00000044-b-2#6091,NA,NA,p.Val153Gly,-0.24,-0.21,1,V483G +urn:mavedb:00000044-b-2#6092,NA,NA,p.Val153Gly,-0.19,-0.21,2,V483G +urn:mavedb:00000044-b-2#6093,NA,NA,p.Val153His,-0.12,-0.09,1,V483H +urn:mavedb:00000044-b-2#6094,NA,NA,p.Val153His,-0.07,-0.09,2,V483H +urn:mavedb:00000044-b-2#6095,NA,NA,p.Val153Ile,-0.23,-0.14,1,V483I +urn:mavedb:00000044-b-2#6096,NA,NA,p.Val153Ile,-0.06,-0.14,2,V483I +urn:mavedb:00000044-b-2#6099,NA,NA,p.Val153Leu,-0.05,-0.02,1,V483L +urn:mavedb:00000044-b-2#6100,NA,NA,p.Val153Leu,0.01,-0.02,2,V483L +urn:mavedb:00000044-b-2#6097,NA,NA,p.Val153Lys,0.01,0.14,1,V483K +urn:mavedb:00000044-b-2#6098,NA,NA,p.Val153Lys,0.27,0.14,2,V483K +urn:mavedb:00000044-b-2#6101,NA,NA,p.Val153Met,0.05,0.03,1,V483M +urn:mavedb:00000044-b-2#6102,NA,NA,p.Val153Met,0.02,0.03,2,V483M +urn:mavedb:00000044-b-2#6089,NA,NA,p.Val153Phe,-0.29,-0.31,1,V483F +urn:mavedb:00000044-b-2#6090,NA,NA,p.Val153Phe,-0.33,-0.31,2,V483F +urn:mavedb:00000044-b-2#6105,NA,NA,p.Val153Pro,-0.49,-0.44,1,V483P +urn:mavedb:00000044-b-2#6106,NA,NA,p.Val153Pro,-0.38,-0.44,2,V483P +urn:mavedb:00000044-b-2#6111,NA,NA,p.Val153Ser,0.04,0.08,1,V483S +urn:mavedb:00000044-b-2#6112,NA,NA,p.Val153Ser,0.12,0.08,2,V483S +urn:mavedb:00000044-b-2#6113,NA,NA,p.Val153Thr,0.29,0.3,1,V483T +urn:mavedb:00000044-b-2#6114,NA,NA,p.Val153Thr,0.31,0.3,2,V483T +urn:mavedb:00000044-b-2#6115,NA,NA,p.Val153Trp,-1.31,-0.83,1,V483W +urn:mavedb:00000044-b-2#6116,NA,NA,p.Val153Trp,-0.35,-0.83,2,V483W +urn:mavedb:00000044-b-2#6117,NA,NA,p.Val153Tyr,-0.11,-0.26,1,V483Y +urn:mavedb:00000044-b-2#6118,NA,NA,p.Val153Tyr,-0.41,-0.26,2,V483Y +urn:mavedb:00000044-b-2#6919,NA,NA,p.Val173*,-4.59,-4.56,1,V503 +urn:mavedb:00000044-b-2#6920,NA,NA,p.Val173*,-4.54,-4.56,2,V503 +urn:mavedb:00000044-b-2#6881,NA,NA,p.Val173Ala,-0.17,-0.1,1,V503A +urn:mavedb:00000044-b-2#6882,NA,NA,p.Val173Ala,-0.04,-0.1,2,V503A +urn:mavedb:00000044-b-2#6909,NA,NA,p.Val173Arg,-0.18,-0.15,1,V503R +urn:mavedb:00000044-b-2#6910,NA,NA,p.Val173Arg,-0.12,-0.15,2,V503R +urn:mavedb:00000044-b-2#6903,NA,NA,p.Val173Asn,-0.23,-0.29,1,V503N +urn:mavedb:00000044-b-2#6904,NA,NA,p.Val173Asn,-0.36,-0.29,2,V503N +urn:mavedb:00000044-b-2#6885,NA,NA,p.Val173Asp,-0.03,-0.11,1,V503D +urn:mavedb:00000044-b-2#6886,NA,NA,p.Val173Asp,-0.19,-0.11,2,V503D +urn:mavedb:00000044-b-2#6883,NA,NA,p.Val173Cys,-0.25,-0.22,1,V503C +urn:mavedb:00000044-b-2#6884,NA,NA,p.Val173Cys,-0.19,-0.22,2,V503C +urn:mavedb:00000044-b-2#6907,NA,NA,p.Val173Gln,-0.01,-0.11,1,V503Q +urn:mavedb:00000044-b-2#6908,NA,NA,p.Val173Gln,-0.21,-0.11,2,V503Q +urn:mavedb:00000044-b-2#6887,NA,NA,p.Val173Glu,0.06,0.07,1,V503E +urn:mavedb:00000044-b-2#6888,NA,NA,p.Val173Glu,0.09,0.07,2,V503E +urn:mavedb:00000044-b-2#6891,NA,NA,p.Val173Gly,-0.5,-0.49,1,V503G +urn:mavedb:00000044-b-2#6892,NA,NA,p.Val173Gly,-0.49,-0.49,2,V503G +urn:mavedb:00000044-b-2#6893,NA,NA,p.Val173His,-0.41,-0.33,1,V503H +urn:mavedb:00000044-b-2#6894,NA,NA,p.Val173His,-0.26,-0.33,2,V503H +urn:mavedb:00000044-b-2#6895,NA,NA,p.Val173Ile,0.02,-0.05,1,V503I +urn:mavedb:00000044-b-2#6896,NA,NA,p.Val173Ile,-0.12,-0.05,2,V503I +urn:mavedb:00000044-b-2#6899,NA,NA,p.Val173Leu,0.06,0.04,1,V503L +urn:mavedb:00000044-b-2#6900,NA,NA,p.Val173Leu,0.01,0.04,2,V503L +urn:mavedb:00000044-b-2#6897,NA,NA,p.Val173Lys,0.02,0.01,1,V503K +urn:mavedb:00000044-b-2#6898,NA,NA,p.Val173Lys,-0.01,0.01,2,V503K +urn:mavedb:00000044-b-2#6901,NA,NA,p.Val173Met,-0.12,-0.12,1,V503M +urn:mavedb:00000044-b-2#6902,NA,NA,p.Val173Met,-0.12,-0.12,2,V503M +urn:mavedb:00000044-b-2#6889,NA,NA,p.Val173Phe,-0.45,-0.38,1,V503F +urn:mavedb:00000044-b-2#6890,NA,NA,p.Val173Phe,-0.32,-0.38,2,V503F +urn:mavedb:00000044-b-2#6905,NA,NA,p.Val173Pro,-1.56,-1.66,1,V503P +urn:mavedb:00000044-b-2#6906,NA,NA,p.Val173Pro,-1.76,-1.66,2,V503P +urn:mavedb:00000044-b-2#6911,NA,NA,p.Val173Ser,-0.17,-0.21,1,V503S +urn:mavedb:00000044-b-2#6912,NA,NA,p.Val173Ser,-0.25,-0.21,2,V503S +urn:mavedb:00000044-b-2#6913,NA,NA,p.Val173Thr,-0.11,-0.12,1,V503T +urn:mavedb:00000044-b-2#6914,NA,NA,p.Val173Thr,-0.13,-0.12,2,V503T +urn:mavedb:00000044-b-2#6915,NA,NA,p.Val173Trp,-0.6,-0.61,1,V503W +urn:mavedb:00000044-b-2#6916,NA,NA,p.Val173Trp,-0.61,-0.61,2,V503W +urn:mavedb:00000044-b-2#6917,NA,NA,p.Val173Tyr,-0.81,-0.57,1,V503Y +urn:mavedb:00000044-b-2#6918,NA,NA,p.Val173Tyr,-0.33,-0.57,2,V503Y +urn:mavedb:00000044-b-2#7199,NA,NA,p.Val180*,-4.64,-4.61,1,V510 +urn:mavedb:00000044-b-2#7200,NA,NA,p.Val180*,-4.58,-4.61,2,V510 +urn:mavedb:00000044-b-2#7161,NA,NA,p.Val180Ala,-2.89,-2.61,1,V510A +urn:mavedb:00000044-b-2#7162,NA,NA,p.Val180Ala,-2.32,-2.61,2,V510A +urn:mavedb:00000044-b-2#7189,NA,NA,p.Val180Arg,-3.17,-3.12,1,V510R +urn:mavedb:00000044-b-2#7190,NA,NA,p.Val180Arg,-3.07,-3.12,2,V510R +urn:mavedb:00000044-b-2#7183,NA,NA,p.Val180Asn,-3.11,-2.98,1,V510N +urn:mavedb:00000044-b-2#7184,NA,NA,p.Val180Asn,-2.85,-2.98,2,V510N +urn:mavedb:00000044-b-2#7165,NA,NA,p.Val180Asp,-3.57,-3.36,1,V510D +urn:mavedb:00000044-b-2#7166,NA,NA,p.Val180Asp,-3.15,-3.36,2,V510D +urn:mavedb:00000044-b-2#7163,NA,NA,p.Val180Cys,-2.88,-1.86,1,V510C +urn:mavedb:00000044-b-2#7164,NA,NA,p.Val180Cys,-0.83,-1.86,2,V510C +urn:mavedb:00000044-b-2#7187,NA,NA,p.Val180Gln,-3.15,-3.05,1,V510Q +urn:mavedb:00000044-b-2#7188,NA,NA,p.Val180Gln,-2.94,-3.05,2,V510Q +urn:mavedb:00000044-b-2#7167,NA,NA,p.Val180Glu,-3.16,-3.05,1,V510E +urn:mavedb:00000044-b-2#7168,NA,NA,p.Val180Glu,-2.95,-3.05,2,V510E +urn:mavedb:00000044-b-2#7171,NA,NA,p.Val180Gly,-3.09,-2.92,1,V510G +urn:mavedb:00000044-b-2#7172,NA,NA,p.Val180Gly,-2.75,-2.92,2,V510G +urn:mavedb:00000044-b-2#7173,NA,NA,p.Val180His,-3.2,-3.08,1,V510H +urn:mavedb:00000044-b-2#7174,NA,NA,p.Val180His,-2.97,-3.08,2,V510H +urn:mavedb:00000044-b-2#7175,NA,NA,p.Val180Ile,-0.83,-0.76,1,V510I +urn:mavedb:00000044-b-2#7176,NA,NA,p.Val180Ile,-0.69,-0.76,2,V510I +urn:mavedb:00000044-b-2#7179,NA,NA,p.Val180Leu,-2.24,-2.2,1,V510L +urn:mavedb:00000044-b-2#7180,NA,NA,p.Val180Leu,-2.15,-2.2,2,V510L +urn:mavedb:00000044-b-2#7177,NA,NA,p.Val180Lys,-3.19,-3.14,1,V510K +urn:mavedb:00000044-b-2#7178,NA,NA,p.Val180Lys,-3.1,-3.14,2,V510K +urn:mavedb:00000044-b-2#7181,NA,NA,p.Val180Met,-2.12,-2.03,1,V510M +urn:mavedb:00000044-b-2#7182,NA,NA,p.Val180Met,-1.95,-2.03,2,V510M +urn:mavedb:00000044-b-2#7169,NA,NA,p.Val180Phe,-2.85,-2.65,1,V510F +urn:mavedb:00000044-b-2#7170,NA,NA,p.Val180Phe,-2.45,-2.65,2,V510F +urn:mavedb:00000044-b-2#7185,NA,NA,p.Val180Pro,-3.23,-3.2,1,V510P +urn:mavedb:00000044-b-2#7186,NA,NA,p.Val180Pro,-3.17,-3.2,2,V510P +urn:mavedb:00000044-b-2#7191,NA,NA,p.Val180Ser,-3.03,-2.99,1,V510S +urn:mavedb:00000044-b-2#7192,NA,NA,p.Val180Ser,-2.96,-2.99,2,V510S +urn:mavedb:00000044-b-2#7193,NA,NA,p.Val180Thr,-2.93,-2.91,1,V510T +urn:mavedb:00000044-b-2#7194,NA,NA,p.Val180Thr,-2.88,-2.91,2,V510T +urn:mavedb:00000044-b-2#7195,NA,NA,p.Val180Trp,-2.86,-2.79,1,V510W +urn:mavedb:00000044-b-2#7196,NA,NA,p.Val180Trp,-2.72,-2.79,2,V510W +urn:mavedb:00000044-b-2#7197,NA,NA,p.Val180Tyr,-2.87,-2.65,1,V510Y +urn:mavedb:00000044-b-2#7198,NA,NA,p.Val180Tyr,-2.43,-2.65,2,V510Y +urn:mavedb:00000044-b-2#7239,NA,NA,p.Val181*,-4.08,-4.29,1,V511 +urn:mavedb:00000044-b-2#7240,NA,NA,p.Val181*,-4.5,-4.29,2,V511 +urn:mavedb:00000044-b-2#7201,NA,NA,p.Val181Ala,-2.72,-2.59,1,V511A +urn:mavedb:00000044-b-2#7202,NA,NA,p.Val181Ala,-2.46,-2.59,2,V511A +urn:mavedb:00000044-b-2#7229,NA,NA,p.Val181Arg,-3.04,-3,1,V511R +urn:mavedb:00000044-b-2#7230,NA,NA,p.Val181Arg,-2.96,-3,2,V511R +urn:mavedb:00000044-b-2#7223,NA,NA,p.Val181Asn,-3,-2.91,1,V511N +urn:mavedb:00000044-b-2#7224,NA,NA,p.Val181Asn,-2.82,-2.91,2,V511N +urn:mavedb:00000044-b-2#7205,NA,NA,p.Val181Asp,-2.88,-2.81,1,V511D +urn:mavedb:00000044-b-2#7206,NA,NA,p.Val181Asp,-2.75,-2.81,2,V511D +urn:mavedb:00000044-b-2#7203,NA,NA,p.Val181Cys,-2.88,-2.53,1,V511C +urn:mavedb:00000044-b-2#7204,NA,NA,p.Val181Cys,-2.19,-2.53,2,V511C +urn:mavedb:00000044-b-2#7227,NA,NA,p.Val181Gln,-2.87,-2.87,1,V511Q +urn:mavedb:00000044-b-2#7228,NA,NA,p.Val181Gln,-2.86,-2.87,2,V511Q +urn:mavedb:00000044-b-2#7207,NA,NA,p.Val181Glu,-3.06,-2.99,1,V511E +urn:mavedb:00000044-b-2#7208,NA,NA,p.Val181Glu,-2.92,-2.99,2,V511E +urn:mavedb:00000044-b-2#7211,NA,NA,p.Val181Gly,-3.14,-3.06,1,V511G +urn:mavedb:00000044-b-2#7212,NA,NA,p.Val181Gly,-2.99,-3.06,2,V511G +urn:mavedb:00000044-b-2#7213,NA,NA,p.Val181His,-3.03,-2.89,1,V511H +urn:mavedb:00000044-b-2#7214,NA,NA,p.Val181His,-2.76,-2.89,2,V511H +urn:mavedb:00000044-b-2#7215,NA,NA,p.Val181Ile,-1.07,-1.2,1,V511I +urn:mavedb:00000044-b-2#7216,NA,NA,p.Val181Ile,-1.32,-1.2,2,V511I +urn:mavedb:00000044-b-2#7219,NA,NA,p.Val181Leu,-2.08,-2.06,1,V511L +urn:mavedb:00000044-b-2#7220,NA,NA,p.Val181Leu,-2.05,-2.06,2,V511L +urn:mavedb:00000044-b-2#7217,NA,NA,p.Val181Lys,-3.21,-3.06,1,V511K +urn:mavedb:00000044-b-2#7218,NA,NA,p.Val181Lys,-2.92,-3.06,2,V511K +urn:mavedb:00000044-b-2#7221,NA,NA,p.Val181Met,-2.4,-2.6,1,V511M +urn:mavedb:00000044-b-2#7222,NA,NA,p.Val181Met,-2.8,-2.6,2,V511M +urn:mavedb:00000044-b-2#7209,NA,NA,p.Val181Phe,-2.53,-2.6,1,V511F +urn:mavedb:00000044-b-2#7210,NA,NA,p.Val181Phe,-2.66,-2.6,2,V511F +urn:mavedb:00000044-b-2#7225,NA,NA,p.Val181Pro,-3.48,-3.24,1,V511P +urn:mavedb:00000044-b-2#7226,NA,NA,p.Val181Pro,-3,-3.24,2,V511P +urn:mavedb:00000044-b-2#7231,NA,NA,p.Val181Ser,-3.05,-2.93,1,V511S +urn:mavedb:00000044-b-2#7232,NA,NA,p.Val181Ser,-2.82,-2.93,2,V511S +urn:mavedb:00000044-b-2#7233,NA,NA,p.Val181Thr,-2.85,-2.7,1,V511T +urn:mavedb:00000044-b-2#7234,NA,NA,p.Val181Thr,-2.54,-2.7,2,V511T +urn:mavedb:00000044-b-2#7235,NA,NA,p.Val181Trp,-2.83,-2.79,1,V511W +urn:mavedb:00000044-b-2#7236,NA,NA,p.Val181Trp,-2.75,-2.79,2,V511W +urn:mavedb:00000044-b-2#7237,NA,NA,p.Val181Tyr,-2.53,-2.42,1,V511Y +urn:mavedb:00000044-b-2#7238,NA,NA,p.Val181Tyr,-2.31,-2.42,2,V511Y +urn:mavedb:00000044-b-2#7279,NA,NA,p.Val182*,-3.44,-3.35,1,V512 +urn:mavedb:00000044-b-2#7280,NA,NA,p.Val182*,-3.27,-3.35,2,V512 +urn:mavedb:00000044-b-2#7241,NA,NA,p.Val182Ala,-2.95,-2.6,1,V512A +urn:mavedb:00000044-b-2#7242,NA,NA,p.Val182Ala,-2.24,-2.6,2,V512A +urn:mavedb:00000044-b-2#7269,NA,NA,p.Val182Arg,-3.13,-3,1,V512R +urn:mavedb:00000044-b-2#7270,NA,NA,p.Val182Arg,-2.87,-3,2,V512R +urn:mavedb:00000044-b-2#7263,NA,NA,p.Val182Asn,-3.22,-3.13,1,V512N +urn:mavedb:00000044-b-2#7264,NA,NA,p.Val182Asn,-3.04,-3.13,2,V512N +urn:mavedb:00000044-b-2#7245,NA,NA,p.Val182Asp,-3.58,-3.44,1,V512D +urn:mavedb:00000044-b-2#7246,NA,NA,p.Val182Asp,-3.29,-3.44,2,V512D +urn:mavedb:00000044-b-2#7243,NA,NA,p.Val182Cys,-1.55,-1.78,1,V512C +urn:mavedb:00000044-b-2#7244,NA,NA,p.Val182Cys,-2.01,-1.78,2,V512C +urn:mavedb:00000044-b-2#7267,NA,NA,p.Val182Gln,-3.1,-3,1,V512Q +urn:mavedb:00000044-b-2#7268,NA,NA,p.Val182Gln,-2.9,-3,2,V512Q +urn:mavedb:00000044-b-2#7247,NA,NA,p.Val182Glu,-3.32,-3.21,1,V512E +urn:mavedb:00000044-b-2#7248,NA,NA,p.Val182Glu,-3.1,-3.21,2,V512E +urn:mavedb:00000044-b-2#7251,NA,NA,p.Val182Gly,-3.11,-3.06,1,V512G +urn:mavedb:00000044-b-2#7252,NA,NA,p.Val182Gly,-3.01,-3.06,2,V512G +urn:mavedb:00000044-b-2#7253,NA,NA,p.Val182His,-3,-3.05,1,V512H +urn:mavedb:00000044-b-2#7254,NA,NA,p.Val182His,-3.09,-3.05,2,V512H +urn:mavedb:00000044-b-2#7255,NA,NA,p.Val182Ile,-0.77,-0.69,1,V512I +urn:mavedb:00000044-b-2#7256,NA,NA,p.Val182Ile,-0.6,-0.69,2,V512I +urn:mavedb:00000044-b-2#7259,NA,NA,p.Val182Leu,-2.8,-2.79,1,V512L +urn:mavedb:00000044-b-2#7260,NA,NA,p.Val182Leu,-2.78,-2.79,2,V512L +urn:mavedb:00000044-b-2#7257,NA,NA,p.Val182Lys,-3.07,-3.01,1,V512K +urn:mavedb:00000044-b-2#7258,NA,NA,p.Val182Lys,-2.95,-3.01,2,V512K +urn:mavedb:00000044-b-2#7261,NA,NA,p.Val182Met,-2.95,-2.63,1,V512M +urn:mavedb:00000044-b-2#7262,NA,NA,p.Val182Met,-2.31,-2.63,2,V512M +urn:mavedb:00000044-b-2#7249,NA,NA,p.Val182Phe,-2.98,-2.88,1,V512F +urn:mavedb:00000044-b-2#7250,NA,NA,p.Val182Phe,-2.78,-2.88,2,V512F +urn:mavedb:00000044-b-2#7265,NA,NA,p.Val182Pro,-3.55,-3.45,1,V512P +urn:mavedb:00000044-b-2#7266,NA,NA,p.Val182Pro,-3.34,-3.45,2,V512P +urn:mavedb:00000044-b-2#7271,NA,NA,p.Val182Ser,-3.08,-3.01,1,V512S +urn:mavedb:00000044-b-2#7272,NA,NA,p.Val182Ser,-2.94,-3.01,2,V512S +urn:mavedb:00000044-b-2#7273,NA,NA,p.Val182Thr,-3.14,-2.81,1,V512T +urn:mavedb:00000044-b-2#7274,NA,NA,p.Val182Thr,-2.49,-2.81,2,V512T +urn:mavedb:00000044-b-2#7275,NA,NA,p.Val182Trp,-2.87,-2.84,1,V512W +urn:mavedb:00000044-b-2#7276,NA,NA,p.Val182Trp,-2.81,-2.84,2,V512W +urn:mavedb:00000044-b-2#7277,NA,NA,p.Val182Tyr,-3.06,-2.99,1,V512Y +urn:mavedb:00000044-b-2#7278,NA,NA,p.Val182Tyr,-2.92,-2.99,2,V512Y +urn:mavedb:00000044-b-2#7759,NA,NA,p.Val194*,NA,-2.83,1,V524 +urn:mavedb:00000044-b-2#7760,NA,NA,p.Val194*,-2.83,-2.83,2,V524 +urn:mavedb:00000044-b-2#7721,NA,NA,p.Val194Ala,-0.07,-0.09,1,V524A +urn:mavedb:00000044-b-2#7722,NA,NA,p.Val194Ala,-0.1,-0.09,2,V524A +urn:mavedb:00000044-b-2#7749,NA,NA,p.Val194Arg,NA,0.54,1,V524R +urn:mavedb:00000044-b-2#7750,NA,NA,p.Val194Arg,0.54,0.54,2,V524R +urn:mavedb:00000044-b-2#7743,NA,NA,p.Val194Asn,NA,NA,1,V524N +urn:mavedb:00000044-b-2#7744,NA,NA,p.Val194Asn,NA,NA,2,V524N +urn:mavedb:00000044-b-2#7725,NA,NA,p.Val194Asp,-0.41,-0.2,1,V524D +urn:mavedb:00000044-b-2#7726,NA,NA,p.Val194Asp,0,-0.2,2,V524D +urn:mavedb:00000044-b-2#7723,NA,NA,p.Val194Cys,NA,NA,1,V524C +urn:mavedb:00000044-b-2#7724,NA,NA,p.Val194Cys,NA,NA,2,V524C +urn:mavedb:00000044-b-2#7747,NA,NA,p.Val194Gln,NA,NA,1,V524Q +urn:mavedb:00000044-b-2#7748,NA,NA,p.Val194Gln,NA,NA,2,V524Q +urn:mavedb:00000044-b-2#7727,NA,NA,p.Val194Glu,NA,NA,1,V524E +urn:mavedb:00000044-b-2#7728,NA,NA,p.Val194Glu,NA,NA,2,V524E +urn:mavedb:00000044-b-2#7731,NA,NA,p.Val194Gly,-0.28,-0.12,1,V524G +urn:mavedb:00000044-b-2#7732,NA,NA,p.Val194Gly,0.03,-0.12,2,V524G +urn:mavedb:00000044-b-2#7733,NA,NA,p.Val194His,NA,NA,1,V524H +urn:mavedb:00000044-b-2#7734,NA,NA,p.Val194His,NA,NA,2,V524H +urn:mavedb:00000044-b-2#7735,NA,NA,p.Val194Ile,-0.13,-0.14,1,V524I +urn:mavedb:00000044-b-2#7736,NA,NA,p.Val194Ile,-0.16,-0.14,2,V524I +urn:mavedb:00000044-b-2#7739,NA,NA,p.Val194Leu,-0.1,-0.15,1,V524L +urn:mavedb:00000044-b-2#7740,NA,NA,p.Val194Leu,-0.19,-0.15,2,V524L +urn:mavedb:00000044-b-2#7737,NA,NA,p.Val194Lys,NA,NA,1,V524K +urn:mavedb:00000044-b-2#7738,NA,NA,p.Val194Lys,NA,NA,2,V524K +urn:mavedb:00000044-b-2#7741,NA,NA,p.Val194Met,NA,NA,1,V524M +urn:mavedb:00000044-b-2#7742,NA,NA,p.Val194Met,NA,NA,2,V524M +urn:mavedb:00000044-b-2#7729,NA,NA,p.Val194Phe,NA,NA,1,V524F +urn:mavedb:00000044-b-2#7730,NA,NA,p.Val194Phe,NA,NA,2,V524F +urn:mavedb:00000044-b-2#7745,NA,NA,p.Val194Pro,0.71,-1.03,1,V524P +urn:mavedb:00000044-b-2#7746,NA,NA,p.Val194Pro,-2.76,-1.03,2,V524P +urn:mavedb:00000044-b-2#7751,NA,NA,p.Val194Ser,NA,NA,1,V524S +urn:mavedb:00000044-b-2#7752,NA,NA,p.Val194Ser,NA,NA,2,V524S +urn:mavedb:00000044-b-2#7753,NA,NA,p.Val194Thr,NA,NA,1,V524T +urn:mavedb:00000044-b-2#7754,NA,NA,p.Val194Thr,NA,NA,2,V524T +urn:mavedb:00000044-b-2#7755,NA,NA,p.Val194Trp,-3,-3,1,V524W +urn:mavedb:00000044-b-2#7756,NA,NA,p.Val194Trp,NA,-3,2,V524W +urn:mavedb:00000044-b-2#7757,NA,NA,p.Val194Tyr,NA,-0.95,1,V524Y +urn:mavedb:00000044-b-2#7758,NA,NA,p.Val194Tyr,-0.95,-0.95,2,V524Y +urn:mavedb:00000044-b-2#799,NA,NA,p.Val20*,-3.26,-3.09,1,V350 +urn:mavedb:00000044-b-2#800,NA,NA,p.Val20*,-2.92,-3.09,2,V350 +urn:mavedb:00000044-b-2#761,NA,NA,p.Val20Ala,-1.42,-1.47,1,V350A +urn:mavedb:00000044-b-2#762,NA,NA,p.Val20Ala,-1.53,-1.47,2,V350A +urn:mavedb:00000044-b-2#789,NA,NA,p.Val20Arg,-2.64,-2.59,1,V350R +urn:mavedb:00000044-b-2#790,NA,NA,p.Val20Arg,-2.53,-2.59,2,V350R +urn:mavedb:00000044-b-2#783,NA,NA,p.Val20Asn,-2.85,-2.51,1,V350N +urn:mavedb:00000044-b-2#784,NA,NA,p.Val20Asn,-2.17,-2.51,2,V350N +urn:mavedb:00000044-b-2#765,NA,NA,p.Val20Asp,-2.2,-2.21,1,V350D +urn:mavedb:00000044-b-2#766,NA,NA,p.Val20Asp,-2.21,-2.21,2,V350D +urn:mavedb:00000044-b-2#763,NA,NA,p.Val20Cys,-0.65,-1.1,1,V350C +urn:mavedb:00000044-b-2#764,NA,NA,p.Val20Cys,-1.54,-1.1,2,V350C +urn:mavedb:00000044-b-2#787,NA,NA,p.Val20Gln,-2.4,-2.57,1,V350Q +urn:mavedb:00000044-b-2#788,NA,NA,p.Val20Gln,-2.75,-2.57,2,V350Q +urn:mavedb:00000044-b-2#767,NA,NA,p.Val20Glu,-2.51,-2.5,1,V350E +urn:mavedb:00000044-b-2#768,NA,NA,p.Val20Glu,-2.49,-2.5,2,V350E +urn:mavedb:00000044-b-2#771,NA,NA,p.Val20Gly,-2.8,-2.81,1,V350G +urn:mavedb:00000044-b-2#772,NA,NA,p.Val20Gly,-2.83,-2.81,2,V350G +urn:mavedb:00000044-b-2#773,NA,NA,p.Val20His,-2.42,-2.39,1,V350H +urn:mavedb:00000044-b-2#774,NA,NA,p.Val20His,-2.37,-2.39,2,V350H +urn:mavedb:00000044-b-2#775,NA,NA,p.Val20Ile,-2.23,-1.88,1,V350I +urn:mavedb:00000044-b-2#776,NA,NA,p.Val20Ile,-1.53,-1.88,2,V350I +urn:mavedb:00000044-b-2#779,NA,NA,p.Val20Leu,-2.67,-2.46,1,V350L +urn:mavedb:00000044-b-2#780,NA,NA,p.Val20Leu,-2.25,-2.46,2,V350L +urn:mavedb:00000044-b-2#777,NA,NA,p.Val20Lys,-2.45,-2.47,1,V350K +urn:mavedb:00000044-b-2#778,NA,NA,p.Val20Lys,-2.48,-2.47,2,V350K +urn:mavedb:00000044-b-2#781,NA,NA,p.Val20Met,-2.53,-2.54,1,V350M +urn:mavedb:00000044-b-2#782,NA,NA,p.Val20Met,-2.55,-2.54,2,V350M +urn:mavedb:00000044-b-2#769,NA,NA,p.Val20Phe,NA,-2.09,1,V350F +urn:mavedb:00000044-b-2#770,NA,NA,p.Val20Phe,-2.09,-2.09,2,V350F +urn:mavedb:00000044-b-2#785,NA,NA,p.Val20Pro,-1.13,-1.08,1,V350P +urn:mavedb:00000044-b-2#786,NA,NA,p.Val20Pro,-1.03,-1.08,2,V350P +urn:mavedb:00000044-b-2#791,NA,NA,p.Val20Ser,-2.32,-2.24,1,V350S +urn:mavedb:00000044-b-2#792,NA,NA,p.Val20Ser,-2.17,-2.24,2,V350S 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+urn:mavedb:00000044-b-2#1278,NA,NA,p.Val32Tyr,0.3,0.26,2,V362Y +urn:mavedb:00000044-b-2#1479,NA,NA,p.Val37*,-4.63,-4.6,1,V367 +urn:mavedb:00000044-b-2#1480,NA,NA,p.Val37*,-4.56,-4.6,2,V367 +urn:mavedb:00000044-b-2#1441,NA,NA,p.Val37Ala,0.38,0.46,1,V367A +urn:mavedb:00000044-b-2#1442,NA,NA,p.Val37Ala,0.54,0.46,2,V367A +urn:mavedb:00000044-b-2#1469,NA,NA,p.Val37Arg,0.09,0.1,1,V367R +urn:mavedb:00000044-b-2#1470,NA,NA,p.Val37Arg,0.12,0.1,2,V367R +urn:mavedb:00000044-b-2#1463,NA,NA,p.Val37Asn,0.04,0.08,1,V367N +urn:mavedb:00000044-b-2#1464,NA,NA,p.Val37Asn,0.12,0.08,2,V367N +urn:mavedb:00000044-b-2#1445,NA,NA,p.Val37Asp,0.12,0.11,1,V367D +urn:mavedb:00000044-b-2#1446,NA,NA,p.Val37Asp,0.11,0.11,2,V367D +urn:mavedb:00000044-b-2#1443,NA,NA,p.Val37Cys,-0.22,-0.22,1,V367C +urn:mavedb:00000044-b-2#1444,NA,NA,p.Val37Cys,-0.21,-0.22,2,V367C +urn:mavedb:00000044-b-2#1467,NA,NA,p.Val37Gln,0.26,0.28,1,V367Q +urn:mavedb:00000044-b-2#1468,NA,NA,p.Val37Gln,0.3,0.28,2,V367Q 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+urn:mavedb:00000044-b-2#1450,NA,NA,p.Val37Phe,0.74,0.74,2,V367F +urn:mavedb:00000044-b-2#1465,NA,NA,p.Val37Pro,-0.1,-0.07,1,V367P +urn:mavedb:00000044-b-2#1466,NA,NA,p.Val37Pro,-0.04,-0.07,2,V367P +urn:mavedb:00000044-b-2#1471,NA,NA,p.Val37Ser,0.28,0.3,1,V367S +urn:mavedb:00000044-b-2#1472,NA,NA,p.Val37Ser,0.33,0.3,2,V367S +urn:mavedb:00000044-b-2#1473,NA,NA,p.Val37Thr,0.21,0.19,1,V367T +urn:mavedb:00000044-b-2#1474,NA,NA,p.Val37Thr,0.17,0.19,2,V367T +urn:mavedb:00000044-b-2#1475,NA,NA,p.Val37Trp,0.31,0.28,1,V367W +urn:mavedb:00000044-b-2#1476,NA,NA,p.Val37Trp,0.24,0.28,2,V367W +urn:mavedb:00000044-b-2#1477,NA,NA,p.Val37Tyr,-0.04,0.01,1,V367Y +urn:mavedb:00000044-b-2#1478,NA,NA,p.Val37Tyr,0.05,0.01,2,V367Y +urn:mavedb:00000044-b-2#2079,NA,NA,p.Val52*,-4.5,-4.37,1,V382 +urn:mavedb:00000044-b-2#2080,NA,NA,p.Val52*,-4.24,-4.37,2,V382 +urn:mavedb:00000044-b-2#2041,NA,NA,p.Val52Ala,-1.53,-1.39,1,V382A +urn:mavedb:00000044-b-2#2042,NA,NA,p.Val52Ala,-1.24,-1.39,2,V382A +urn:mavedb:00000044-b-2#2069,NA,NA,p.Val52Arg,-2.17,-2.21,1,V382R +urn:mavedb:00000044-b-2#2070,NA,NA,p.Val52Arg,-2.26,-2.21,2,V382R +urn:mavedb:00000044-b-2#2063,NA,NA,p.Val52Asn,-1.96,-2.03,1,V382N +urn:mavedb:00000044-b-2#2064,NA,NA,p.Val52Asn,-2.11,-2.03,2,V382N +urn:mavedb:00000044-b-2#2045,NA,NA,p.Val52Asp,-2.48,-2.28,1,V382D +urn:mavedb:00000044-b-2#2046,NA,NA,p.Val52Asp,-2.07,-2.28,2,V382D +urn:mavedb:00000044-b-2#2043,NA,NA,p.Val52Cys,-0.48,-0.44,1,V382C +urn:mavedb:00000044-b-2#2044,NA,NA,p.Val52Cys,-0.4,-0.44,2,V382C +urn:mavedb:00000044-b-2#2067,NA,NA,p.Val52Gln,-2.02,-2.09,1,V382Q +urn:mavedb:00000044-b-2#2068,NA,NA,p.Val52Gln,-2.16,-2.09,2,V382Q +urn:mavedb:00000044-b-2#2047,NA,NA,p.Val52Glu,-2.21,-1.79,1,V382E +urn:mavedb:00000044-b-2#2048,NA,NA,p.Val52Glu,-1.37,-1.79,2,V382E +urn:mavedb:00000044-b-2#2051,NA,NA,p.Val52Gly,-2.37,-2.29,1,V382G +urn:mavedb:00000044-b-2#2052,NA,NA,p.Val52Gly,-2.2,-2.29,2,V382G +urn:mavedb:00000044-b-2#2053,NA,NA,p.Val52His,-1.56,-1.73,1,V382H +urn:mavedb:00000044-b-2#2054,NA,NA,p.Val52His,-1.9,-1.73,2,V382H +urn:mavedb:00000044-b-2#2055,NA,NA,p.Val52Ile,-0.08,-0.07,1,V382I +urn:mavedb:00000044-b-2#2056,NA,NA,p.Val52Ile,-0.07,-0.07,2,V382I +urn:mavedb:00000044-b-2#2059,NA,NA,p.Val52Leu,-0.28,-0.25,1,V382L +urn:mavedb:00000044-b-2#2060,NA,NA,p.Val52Leu,-0.22,-0.25,2,V382L +urn:mavedb:00000044-b-2#2057,NA,NA,p.Val52Lys,-2.11,-2,1,V382K +urn:mavedb:00000044-b-2#2058,NA,NA,p.Val52Lys,-1.89,-2,2,V382K +urn:mavedb:00000044-b-2#2061,NA,NA,p.Val52Met,-0.39,-0.48,1,V382M +urn:mavedb:00000044-b-2#2062,NA,NA,p.Val52Met,-0.57,-0.48,2,V382M +urn:mavedb:00000044-b-2#2049,NA,NA,p.Val52Phe,-0.26,-0.11,1,V382F +urn:mavedb:00000044-b-2#2050,NA,NA,p.Val52Phe,0.03,-0.11,2,V382F +urn:mavedb:00000044-b-2#2065,NA,NA,p.Val52Pro,-1.8,-1.8,1,V382P +urn:mavedb:00000044-b-2#2066,NA,NA,p.Val52Pro,-1.79,-1.8,2,V382P +urn:mavedb:00000044-b-2#2071,NA,NA,p.Val52Ser,-1.96,-1.92,1,V382S +urn:mavedb:00000044-b-2#2072,NA,NA,p.Val52Ser,-1.87,-1.92,2,V382S +urn:mavedb:00000044-b-2#2073,NA,NA,p.Val52Thr,-0.96,-0.9,1,V382T +urn:mavedb:00000044-b-2#2074,NA,NA,p.Val52Thr,-0.83,-0.9,2,V382T +urn:mavedb:00000044-b-2#2075,NA,NA,p.Val52Trp,-1.27,-1.39,1,V382W +urn:mavedb:00000044-b-2#2076,NA,NA,p.Val52Trp,-1.5,-1.39,2,V382W +urn:mavedb:00000044-b-2#2077,NA,NA,p.Val52Tyr,-1,-0.82,1,V382Y +urn:mavedb:00000044-b-2#2078,NA,NA,p.Val52Tyr,-0.64,-0.82,2,V382Y +urn:mavedb:00000044-b-2#2599,NA,NA,p.Val65*,-4.62,-4.58,1,V395 +urn:mavedb:00000044-b-2#2600,NA,NA,p.Val65*,-4.55,-4.58,2,V395 +urn:mavedb:00000044-b-2#2561,NA,NA,p.Val65Ala,-0.37,-0.35,1,V395A +urn:mavedb:00000044-b-2#2562,NA,NA,p.Val65Ala,-0.32,-0.35,2,V395A +urn:mavedb:00000044-b-2#2589,NA,NA,p.Val65Arg,-1.59,-1.53,1,V395R +urn:mavedb:00000044-b-2#2590,NA,NA,p.Val65Arg,-1.47,-1.53,2,V395R +urn:mavedb:00000044-b-2#2583,NA,NA,p.Val65Asn,-2.88,-2.71,1,V395N +urn:mavedb:00000044-b-2#2584,NA,NA,p.Val65Asn,-2.54,-2.71,2,V395N +urn:mavedb:00000044-b-2#2565,NA,NA,p.Val65Asp,-2.22,-2.54,1,V395D +urn:mavedb:00000044-b-2#2566,NA,NA,p.Val65Asp,-2.85,-2.54,2,V395D +urn:mavedb:00000044-b-2#2563,NA,NA,p.Val65Cys,-0.32,-0.23,1,V395C +urn:mavedb:00000044-b-2#2564,NA,NA,p.Val65Cys,-0.14,-0.23,2,V395C +urn:mavedb:00000044-b-2#2587,NA,NA,p.Val65Gln,-2.09,-2.03,1,V395Q +urn:mavedb:00000044-b-2#2588,NA,NA,p.Val65Gln,-1.98,-2.03,2,V395Q +urn:mavedb:00000044-b-2#2567,NA,NA,p.Val65Glu,-2.62,-2.55,1,V395E +urn:mavedb:00000044-b-2#2568,NA,NA,p.Val65Glu,-2.47,-2.55,2,V395E +urn:mavedb:00000044-b-2#2571,NA,NA,p.Val65Gly,-0.66,-0.56,1,V395G +urn:mavedb:00000044-b-2#2572,NA,NA,p.Val65Gly,-0.47,-0.56,2,V395G +urn:mavedb:00000044-b-2#2573,NA,NA,p.Val65His,-2.14,-2.45,1,V395H +urn:mavedb:00000044-b-2#2574,NA,NA,p.Val65His,-2.76,-2.45,2,V395H +urn:mavedb:00000044-b-2#2575,NA,NA,p.Val65Ile,0.11,0.06,1,V395I +urn:mavedb:00000044-b-2#2576,NA,NA,p.Val65Ile,0.01,0.06,2,V395I +urn:mavedb:00000044-b-2#2579,NA,NA,p.Val65Leu,-0.24,-0.18,1,V395L +urn:mavedb:00000044-b-2#2580,NA,NA,p.Val65Leu,-0.11,-0.18,2,V395L +urn:mavedb:00000044-b-2#2577,NA,NA,p.Val65Lys,-2.6,-2.48,1,V395K +urn:mavedb:00000044-b-2#2578,NA,NA,p.Val65Lys,-2.36,-2.48,2,V395K +urn:mavedb:00000044-b-2#2581,NA,NA,p.Val65Met,-0.4,-0.26,1,V395M +urn:mavedb:00000044-b-2#2582,NA,NA,p.Val65Met,-0.13,-0.26,2,V395M +urn:mavedb:00000044-b-2#2569,NA,NA,p.Val65Phe,-1.2,-1.09,1,V395F +urn:mavedb:00000044-b-2#2570,NA,NA,p.Val65Phe,-0.98,-1.09,2,V395F +urn:mavedb:00000044-b-2#2585,NA,NA,p.Val65Pro,-2.98,-2.84,1,V395P +urn:mavedb:00000044-b-2#2586,NA,NA,p.Val65Pro,-2.7,-2.84,2,V395P +urn:mavedb:00000044-b-2#2591,NA,NA,p.Val65Ser,-1.65,-1.77,1,V395S +urn:mavedb:00000044-b-2#2592,NA,NA,p.Val65Ser,-1.88,-1.77,2,V395S +urn:mavedb:00000044-b-2#2593,NA,NA,p.Val65Thr,-1.24,-1.09,1,V395T +urn:mavedb:00000044-b-2#2594,NA,NA,p.Val65Thr,-0.94,-1.09,2,V395T +urn:mavedb:00000044-b-2#2595,NA,NA,p.Val65Trp,-2.24,-2.26,1,V395W +urn:mavedb:00000044-b-2#2596,NA,NA,p.Val65Trp,-2.27,-2.26,2,V395W +urn:mavedb:00000044-b-2#2597,NA,NA,p.Val65Tyr,-2.41,-2.63,1,V395Y +urn:mavedb:00000044-b-2#2598,NA,NA,p.Val65Tyr,-2.85,-2.63,2,V395Y +urn:mavedb:00000044-b-2#2839,NA,NA,p.Val71*,-4.62,-4.58,1,V401 +urn:mavedb:00000044-b-2#2840,NA,NA,p.Val71*,-4.53,-4.58,2,V401 +urn:mavedb:00000044-b-2#2801,NA,NA,p.Val71Ala,-2.11,-2.02,1,V401A +urn:mavedb:00000044-b-2#2802,NA,NA,p.Val71Ala,-1.93,-2.02,2,V401A +urn:mavedb:00000044-b-2#2829,NA,NA,p.Val71Arg,-2.98,-2.88,1,V401R +urn:mavedb:00000044-b-2#2830,NA,NA,p.Val71Arg,-2.78,-2.88,2,V401R +urn:mavedb:00000044-b-2#2823,NA,NA,p.Val71Asn,-2.88,-2.84,1,V401N +urn:mavedb:00000044-b-2#2824,NA,NA,p.Val71Asn,-2.8,-2.84,2,V401N +urn:mavedb:00000044-b-2#2805,NA,NA,p.Val71Asp,-2.91,-2.67,1,V401D +urn:mavedb:00000044-b-2#2806,NA,NA,p.Val71Asp,-2.44,-2.67,2,V401D +urn:mavedb:00000044-b-2#2803,NA,NA,p.Val71Cys,-2.04,-1.78,1,V401C +urn:mavedb:00000044-b-2#2804,NA,NA,p.Val71Cys,-1.52,-1.78,2,V401C +urn:mavedb:00000044-b-2#2827,NA,NA,p.Val71Gln,-1.91,-2.31,1,V401Q +urn:mavedb:00000044-b-2#2828,NA,NA,p.Val71Gln,-2.72,-2.31,2,V401Q +urn:mavedb:00000044-b-2#2807,NA,NA,p.Val71Glu,-2.6,-2.54,1,V401E +urn:mavedb:00000044-b-2#2808,NA,NA,p.Val71Glu,-2.48,-2.54,2,V401E +urn:mavedb:00000044-b-2#2811,NA,NA,p.Val71Gly,-2.85,-2.81,1,V401G +urn:mavedb:00000044-b-2#2812,NA,NA,p.Val71Gly,-2.77,-2.81,2,V401G +urn:mavedb:00000044-b-2#2813,NA,NA,p.Val71His,-2.77,-2.77,1,V401H +urn:mavedb:00000044-b-2#2814,NA,NA,p.Val71His,-2.77,-2.77,2,V401H +urn:mavedb:00000044-b-2#2815,NA,NA,p.Val71Ile,-0.41,-0.41,1,V401I +urn:mavedb:00000044-b-2#2816,NA,NA,p.Val71Ile,-0.4,-0.41,2,V401I +urn:mavedb:00000044-b-2#2819,NA,NA,p.Val71Leu,-1.57,-1.57,1,V401L +urn:mavedb:00000044-b-2#2820,NA,NA,p.Val71Leu,-1.57,-1.57,2,V401L +urn:mavedb:00000044-b-2#2817,NA,NA,p.Val71Lys,-2.77,-2.75,1,V401K +urn:mavedb:00000044-b-2#2818,NA,NA,p.Val71Lys,-2.73,-2.75,2,V401K +urn:mavedb:00000044-b-2#2821,NA,NA,p.Val71Met,-2.25,-2.19,1,V401M +urn:mavedb:00000044-b-2#2822,NA,NA,p.Val71Met,-2.14,-2.19,2,V401M +urn:mavedb:00000044-b-2#2809,NA,NA,p.Val71Phe,-3.21,-3.03,1,V401F +urn:mavedb:00000044-b-2#2810,NA,NA,p.Val71Phe,-2.85,-3.03,2,V401F +urn:mavedb:00000044-b-2#2825,NA,NA,p.Val71Pro,-2.86,-2.89,1,V401P +urn:mavedb:00000044-b-2#2826,NA,NA,p.Val71Pro,-2.92,-2.89,2,V401P +urn:mavedb:00000044-b-2#2831,NA,NA,p.Val71Ser,-2.76,-2.68,1,V401S +urn:mavedb:00000044-b-2#2832,NA,NA,p.Val71Ser,-2.59,-2.68,2,V401S +urn:mavedb:00000044-b-2#2833,NA,NA,p.Val71Thr,-1.29,-1.22,1,V401T +urn:mavedb:00000044-b-2#2834,NA,NA,p.Val71Thr,-1.14,-1.22,2,V401T +urn:mavedb:00000044-b-2#2835,NA,NA,p.Val71Trp,-2.63,-2.48,1,V401W +urn:mavedb:00000044-b-2#2836,NA,NA,p.Val71Trp,-2.34,-2.48,2,V401W +urn:mavedb:00000044-b-2#2837,NA,NA,p.Val71Tyr,-2.87,-2.75,1,V401Y +urn:mavedb:00000044-b-2#2838,NA,NA,p.Val71Tyr,-2.63,-2.75,2,V401Y +urn:mavedb:00000044-b-2#3079,NA,NA,p.Val77*,-4.56,-4.53,1,V407 +urn:mavedb:00000044-b-2#3080,NA,NA,p.Val77*,-4.5,-4.53,2,V407 +urn:mavedb:00000044-b-2#3041,NA,NA,p.Val77Ala,-2.27,-2.22,1,V407A +urn:mavedb:00000044-b-2#3042,NA,NA,p.Val77Ala,-2.17,-2.22,2,V407A +urn:mavedb:00000044-b-2#3069,NA,NA,p.Val77Arg,-2.2,-2.17,1,V407R +urn:mavedb:00000044-b-2#3070,NA,NA,p.Val77Arg,-2.14,-2.17,2,V407R +urn:mavedb:00000044-b-2#3063,NA,NA,p.Val77Asn,-2.29,-2.51,1,V407N +urn:mavedb:00000044-b-2#3064,NA,NA,p.Val77Asn,-2.74,-2.51,2,V407N +urn:mavedb:00000044-b-2#3045,NA,NA,p.Val77Asp,-2.86,-2.8,1,V407D +urn:mavedb:00000044-b-2#3046,NA,NA,p.Val77Asp,-2.73,-2.8,2,V407D +urn:mavedb:00000044-b-2#3043,NA,NA,p.Val77Cys,-2.31,-2.12,1,V407C +urn:mavedb:00000044-b-2#3044,NA,NA,p.Val77Cys,-1.93,-2.12,2,V407C +urn:mavedb:00000044-b-2#3067,NA,NA,p.Val77Gln,-2.02,-1.99,1,V407Q +urn:mavedb:00000044-b-2#3068,NA,NA,p.Val77Gln,-1.95,-1.99,2,V407Q +urn:mavedb:00000044-b-2#3047,NA,NA,p.Val77Glu,-2.54,-2.54,1,V407E +urn:mavedb:00000044-b-2#3048,NA,NA,p.Val77Glu,-2.53,-2.54,2,V407E +urn:mavedb:00000044-b-2#3051,NA,NA,p.Val77Gly,-2.87,-2.76,1,V407G +urn:mavedb:00000044-b-2#3052,NA,NA,p.Val77Gly,-2.65,-2.76,2,V407G +urn:mavedb:00000044-b-2#3053,NA,NA,p.Val77His,-2.62,-2.73,1,V407H +urn:mavedb:00000044-b-2#3054,NA,NA,p.Val77His,-2.83,-2.73,2,V407H +urn:mavedb:00000044-b-2#3055,NA,NA,p.Val77Ile,-0.43,-0.32,1,V407I +urn:mavedb:00000044-b-2#3056,NA,NA,p.Val77Ile,-0.21,-0.32,2,V407I +urn:mavedb:00000044-b-2#3059,NA,NA,p.Val77Leu,-0.08,-0.06,1,V407L +urn:mavedb:00000044-b-2#3060,NA,NA,p.Val77Leu,-0.04,-0.06,2,V407L +urn:mavedb:00000044-b-2#3057,NA,NA,p.Val77Lys,-2.5,-2.51,1,V407K +urn:mavedb:00000044-b-2#3058,NA,NA,p.Val77Lys,-2.52,-2.51,2,V407K +urn:mavedb:00000044-b-2#3061,NA,NA,p.Val77Met,-1.19,-1.16,1,V407M +urn:mavedb:00000044-b-2#3062,NA,NA,p.Val77Met,-1.13,-1.16,2,V407M +urn:mavedb:00000044-b-2#3049,NA,NA,p.Val77Phe,-2.69,-2.62,1,V407F +urn:mavedb:00000044-b-2#3050,NA,NA,p.Val77Phe,-2.54,-2.62,2,V407F +urn:mavedb:00000044-b-2#3065,NA,NA,p.Val77Pro,-2.84,-2.81,1,V407P +urn:mavedb:00000044-b-2#3066,NA,NA,p.Val77Pro,-2.78,-2.81,2,V407P +urn:mavedb:00000044-b-2#3071,NA,NA,p.Val77Ser,-2.49,-2.5,1,V407S +urn:mavedb:00000044-b-2#3072,NA,NA,p.Val77Ser,-2.51,-2.5,2,V407S +urn:mavedb:00000044-b-2#3073,NA,NA,p.Val77Thr,-1.64,-1.85,1,V407T +urn:mavedb:00000044-b-2#3074,NA,NA,p.Val77Thr,-2.06,-1.85,2,V407T +urn:mavedb:00000044-b-2#3075,NA,NA,p.Val77Trp,-2.64,-2.65,1,V407W +urn:mavedb:00000044-b-2#3076,NA,NA,p.Val77Trp,-2.66,-2.65,2,V407W +urn:mavedb:00000044-b-2#3077,NA,NA,p.Val77Tyr,-2.73,-2.74,1,V407Y +urn:mavedb:00000044-b-2#3078,NA,NA,p.Val77Tyr,-2.76,-2.74,2,V407Y \ No newline at end of file diff --git a/example_data/example_mave_data/input/SARS-CoV-2.gff3 b/example_data/example_mave_data/input/SARS-CoV-2.gff3 new file mode 100644 index 0000000..ff11c7b --- /dev/null +++ b/example_data/example_mave_data/input/SARS-CoV-2.gff3 @@ -0,0 +1,65 @@ +##gff-version 3 +#!gff-spec-version 1.21 +#!processor NCBI annotwriter +##sequence-region NC_045512.2 1 29903 +##species https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=2697049 +NC_045512.2 RefSeq region 1 29903 . + . ID=NC_045512.2:1..29903;Dbxref=taxon:2697049;collection-date=Dec-2019;country=China;gb-acronym=SARS-CoV-2;gbkey=Src;genome=genomic;isolate=Wuhan-Hu-1;mol_type=genomic RNA;nat-host=Homo sapiens;old-name=Wuhan seafood market pneumonia virus +NC_045512.2 RefSeq five_prime_UTR 1 265 . + . ID=id-NC_045512.2:1..265;gbkey=5'UTR +NC_045512.2 RefSeq gene 266 21555 . + . ID=gene-GU280_gp01;Dbxref=GeneID:43740578;Name=ORF1ab;gbkey=Gene;gene=ORF1ab;gene_biotype=protein_coding;locus_tag=GU280_gp01 +NC_045512.2 RefSeq CDS 266 13468 . + 0 ID=cds-YP_009724389.1;Parent=gene-GU280_gp01;Dbxref=GenBank:YP_009724389.1,GeneID:43740578;Name=YP_009724389.1;Note=pp1ab%3B translated by -1 ribosomal frameshift;exception=ribosomal slippage;gbkey=CDS;gene=ORF1ab;locus_tag=GU280_gp01;product=ORF1ab polyprotein;protein_id=YP_009724389.1 +NC_045512.2 RefSeq CDS 13468 21555 . + 0 ID=cds-YP_009724389.1;Parent=gene-GU280_gp01;Dbxref=GenBank:YP_009724389.1,GeneID:43740578;Name=YP_009724389.1;Note=pp1ab%3B translated by -1 ribosomal frameshift;exception=ribosomal slippage;gbkey=CDS;gene=ORF1ab;locus_tag=GU280_gp01;product=ORF1ab polyprotein;protein_id=YP_009724389.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 266 805 . + . ID=id-YP_009724389.1:1..180;Note=nsp1%3B produced by both pp1a and pp1ab;Parent=cds-YP_009724389.1;gbkey=Prot;product=leader protein;protein_id=YP_009725297.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 806 2719 . + . ID=id-YP_009724389.1:181..818;Note=produced by both pp1a and pp1ab;Parent=cds-YP_009724389.1;gbkey=Prot;product=nsp2;protein_id=YP_009725298.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 2720 8554 . + . ID=id-YP_009724389.1:819..2763;Note=former nsp1%3B conserved domains are: N-terminal acidic (Ac)%2C predicted phosphoesterase%2C papain-like proteinase%2C Y-domain%2C transmembrane domain 1 (TM1)%2C adenosine diphosphate-ribose 1''-phosphatase (ADRP)%3B produced by both pp1a and pp1ab;Parent=cds-YP_009724389.1;gbkey=Prot;product=nsp3;protein_id=YP_009725299.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 8555 10054 . + . ID=id-YP_009724389.1:2764..3263;Note=nsp4B_TM%3B contains transmembrane domain 2 (TM2)%3B produced by both pp1a and pp1ab;Parent=cds-YP_009724389.1;gbkey=Prot;product=nsp4;protein_id=YP_009725300.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 10055 10972 . + . ID=id-YP_009724389.1:3264..3569;Note=nsp5A_3CLpro and nsp5B_3CLpro%3B main proteinase (Mpro)%3B mediates cleavages downstream of nsp4. 3D structure of the SARSr-CoV homolog has been determined (Yang et al.%2C 2003)%3B produced by both pp1a and pp1ab;Parent=cds-YP_009724389.1;gbkey=Prot;product=3C-like proteinase;protein_id=YP_009725301.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 10973 11842 . + . ID=id-YP_009724389.1:3570..3859;Note=nsp6_TM%3B putative transmembrane domain%3B produced by both pp1a and pp1ab;Parent=cds-YP_009724389.1;gbkey=Prot;product=nsp6;protein_id=YP_009725302.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 11843 12091 . + . ID=id-YP_009724389.1:3860..3942;Note=produced by both pp1a and pp1ab;Parent=cds-YP_009724389.1;gbkey=Prot;product=nsp7;protein_id=YP_009725303.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 12092 12685 . + . ID=id-YP_009724389.1:3943..4140;Note=produced by both pp1a and pp1ab;Parent=cds-YP_009724389.1;gbkey=Prot;product=nsp8;protein_id=YP_009725304.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 12686 13024 . + . ID=id-YP_009724389.1:4141..4253;Note=ssRNA-binding protein%3B produced by both pp1a and pp1ab;Parent=cds-YP_009724389.1;gbkey=Prot;product=nsp9;protein_id=YP_009725305.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 13025 13441 . + . ID=id-YP_009724389.1:4254..4392;Note=nsp10_CysHis%3B formerly known as growth-factor-like protein (GFL)%3B produced by both pp1a and pp1ab;Parent=cds-YP_009724389.1;gbkey=Prot;product=nsp10;protein_id=YP_009725306.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 13442 13468 . + . ID=id-YP_009724389.1:4393..5324;Note=nsp12%3B NiRAN and RdRp%3B produced by pp1ab only;Parent=cds-YP_009724389.1;gbkey=Prot;product=RNA-dependent RNA polymerase;protein_id=YP_009725307.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 13468 16236 . + . ID=id-YP_009724389.1:4393..5324;Note=nsp12%3B NiRAN and RdRp%3B produced by pp1ab only;Parent=cds-YP_009724389.1;gbkey=Prot;product=RNA-dependent RNA polymerase;protein_id=YP_009725307.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 16237 18039 . + . ID=id-YP_009724389.1:5325..5925;Note=nsp13_ZBD%2C nsp13_TB%2C and nsp_HEL1core%3B zinc-binding domain (ZD)%2C NTPase/helicase domain (HEL)%2C RNA 5'-triphosphatase%3B produced by pp1ab only;Parent=cds-YP_009724389.1;gbkey=Prot;product=helicase;protein_id=YP_009725308.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 18040 19620 . + . ID=id-YP_009724389.1:5926..6452;Note=nsp14A2_ExoN and nsp14B_NMT%3B produced by pp1ab only;Parent=cds-YP_009724389.1;gbkey=Prot;product=3'-to-5' exonuclease;protein_id=YP_009725309.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 19621 20658 . + . ID=id-YP_009724389.1:6453..6798;Note=nsp15-A1 and nsp15B-NendoU%3B produced by pp1ab only;Parent=cds-YP_009724389.1;gbkey=Prot;product=endoRNAse;protein_id=YP_009725310.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 20659 21552 . + . ID=id-YP_009724389.1:6799..7096;Note=nsp16_OMT%3B 2'-o-MT%3B produced by pp1ab only;Parent=cds-YP_009724389.1;gbkey=Prot;product=2'-O-ribose methyltransferase;protein_id=YP_009725311.1 +NC_045512.2 RefSeq CDS 266 13483 . + 0 ID=cds-YP_009725295.1;Parent=gene-GU280_gp01;Dbxref=GenBank:YP_009725295.1,GeneID:43740578;Name=YP_009725295.1;Note=pp1a;gbkey=CDS;gene=ORF1ab;locus_tag=GU280_gp01;product=ORF1a polyprotein;protein_id=YP_009725295.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 266 805 . + . ID=id-YP_009725295.1:1..180;Note=nsp1%3B produced by both pp1a and pp1ab;Parent=cds-YP_009725295.1;gbkey=Prot;product=leader protein;protein_id=YP_009742608.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 806 2719 . + . ID=id-YP_009725295.1:181..818;Note=produced by both pp1a and pp1ab;Parent=cds-YP_009725295.1;gbkey=Prot;product=nsp2;protein_id=YP_009742609.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 2720 8554 . + . ID=id-YP_009725295.1:819..2763;Note=former nsp1%3B conserved domains are: N-terminal acidic (Ac)%2C predicted phosphoesterase%2C papain-like proteinase%2C Y-domain%2C transmembrane domain 1 (TM1)%2C adenosine diphosphate-ribose 1''-phosphatase (ADRP)%3B produced by both pp1a and pp1ab;Parent=cds-YP_009725295.1;gbkey=Prot;product=nsp3;protein_id=YP_009742610.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 8555 10054 . + . ID=id-YP_009725295.1:2764..3263;Note=nsp4B_TM%3B contains transmembrane domain 2 (TM2)%3B produced by both pp1a and pp1ab;Parent=cds-YP_009725295.1;gbkey=Prot;product=nsp4;protein_id=YP_009742611.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 10055 10972 . + . ID=id-YP_009725295.1:3264..3569;Note=nsp5A_3CLpro and nsp5B_3CLpro%3B main proteinase (Mpro)%3B mediates cleavages downstream of nsp4. 3D structure of the SARSr-CoV homolog has been determined (Yang et al.%2C 2003)%3B produced by both pp1a and pp1ab;Parent=cds-YP_009725295.1;gbkey=Prot;product=3C-like proteinase;protein_id=YP_009742612.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 10973 11842 . + . ID=id-YP_009725295.1:3570..3859;Note=nsp6_TM%3B putative transmembrane domain%3B produced by both pp1a and pp1ab;Parent=cds-YP_009725295.1;gbkey=Prot;product=nsp6;protein_id=YP_009742613.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 11843 12091 . + . ID=id-YP_009725295.1:3860..3942;Note=produced by both pp1a and pp1ab;Parent=cds-YP_009725295.1;gbkey=Prot;product=nsp7;protein_id=YP_009742614.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 12092 12685 . + . ID=id-YP_009725295.1:3943..4140;Note=produced by both pp1a and pp1ab;Parent=cds-YP_009725295.1;gbkey=Prot;product=nsp8;protein_id=YP_009742615.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 12686 13024 . + . ID=id-YP_009725295.1:4141..4253;Note=ssRNA-binding protein%3B produced by both pp1a and pp1ab;Parent=cds-YP_009725295.1;gbkey=Prot;product=nsp9;protein_id=YP_009742616.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 13025 13441 . + . ID=id-YP_009725295.1:4254..4392;Note=nsp10_CysHis%3B formerly known as growth-factor-like protein (GFL)%3B produced by both pp1a and pp1ab;Parent=cds-YP_009725295.1;gbkey=Prot;product=nsp10;protein_id=YP_009742617.1 +NC_045512.2 RefSeq mature_protein_region_of_CDS 13442 13480 . + . ID=id-YP_009725295.1:4393..4405;Note=produced by pp1a only;Parent=cds-YP_009725295.1;gbkey=Prot;product=nsp11;protein_id=YP_009725312.1 +NC_045512.2 RefSeq stem_loop 13476 13503 . + . ID=id-GU280_gp01;Dbxref=GeneID:43740578;function=Coronavirus frameshifting stimulation element stem-loop 1;gbkey=stem_loop;gene=ORF1ab;inference=COORDINATES: profile:Rfam-release-14.1:RF00507%2CInfernal:1.1.2;locus_tag=GU280_gp01 +NC_045512.2 RefSeq stem_loop 13488 13542 . + . ID=id-GU280_gp01-2;Dbxref=GeneID:43740578;function=Coronavirus frameshifting stimulation element stem-loop 2;gbkey=stem_loop;gene=ORF1ab;inference=COORDINATES: profile:Rfam-release-14.1:RF00507%2CInfernal:1.1.2;locus_tag=GU280_gp01 +NC_045512.2 RefSeq gene 21563 25384 . + . ID=gene-GU280_gp02;Dbxref=GeneID:43740568;Name=S;gbkey=Gene;gene=S;gene_biotype=protein_coding;gene_synonym=spike glycoprotein;locus_tag=GU280_gp02 +NC_045512.2 RefSeq CDS 21563 25384 . + 0 ID=cds-YP_009724390.1;Parent=gene-GU280_gp02;Dbxref=GenBank:YP_009724390.1,GeneID:43740568;Name=YP_009724390.1;Note=structural protein%3B spike protein;gbkey=CDS;gene=S;locus_tag=GU280_gp02;product=surface glycoprotein;protein_id=YP_009724390.1 +NC_045512.2 RefSeq gene 25393 26220 . + . ID=gene-GU280_gp03;Dbxref=GeneID:43740569;Name=ORF3a;gbkey=Gene;gene=ORF3a;gene_biotype=protein_coding;locus_tag=GU280_gp03 +NC_045512.2 RefSeq CDS 25393 26220 . + 0 ID=cds-YP_009724391.1;Parent=gene-GU280_gp03;Dbxref=GenBank:YP_009724391.1,GeneID:43740569;Name=YP_009724391.1;gbkey=CDS;gene=ORF3a;locus_tag=GU280_gp03;product=ORF3a protein;protein_id=YP_009724391.1 +NC_045512.2 RefSeq gene 26245 26472 . + . ID=gene-GU280_gp04;Dbxref=GeneID:43740570;Name=E;gbkey=Gene;gene=E;gene_biotype=protein_coding;locus_tag=GU280_gp04 +NC_045512.2 RefSeq CDS 26245 26472 . + 0 ID=cds-YP_009724392.1;Parent=gene-GU280_gp04;Dbxref=GenBank:YP_009724392.1,GeneID:43740570;Name=YP_009724392.1;Note=ORF4%3B structural protein%3B E protein;gbkey=CDS;gene=E;locus_tag=GU280_gp04;product=envelope protein;protein_id=YP_009724392.1 +NC_045512.2 RefSeq gene 26523 27191 . + . ID=gene-GU280_gp05;Dbxref=GeneID:43740571;Name=M;gbkey=Gene;gene=M;gene_biotype=protein_coding;locus_tag=GU280_gp05 +NC_045512.2 RefSeq CDS 26523 27191 . + 0 ID=cds-YP_009724393.1;Parent=gene-GU280_gp05;Dbxref=GenBank:YP_009724393.1,GeneID:43740571;Name=YP_009724393.1;Note=ORF5%3B structural protein;gbkey=CDS;gene=M;locus_tag=GU280_gp05;product=membrane glycoprotein;protein_id=YP_009724393.1 +NC_045512.2 RefSeq gene 27202 27387 . + . ID=gene-GU280_gp06;Dbxref=GeneID:43740572;Name=ORF6;gbkey=Gene;gene=ORF6;gene_biotype=protein_coding;locus_tag=GU280_gp06 +NC_045512.2 RefSeq CDS 27202 27387 . + 0 ID=cds-YP_009724394.1;Parent=gene-GU280_gp06;Dbxref=GenBank:YP_009724394.1,GeneID:43740572;Name=YP_009724394.1;gbkey=CDS;gene=ORF6;locus_tag=GU280_gp06;product=ORF6 protein;protein_id=YP_009724394.1 +NC_045512.2 RefSeq gene 27394 27759 . + . ID=gene-GU280_gp07;Dbxref=GeneID:43740573;Name=ORF7a;gbkey=Gene;gene=ORF7a;gene_biotype=protein_coding;locus_tag=GU280_gp07 +NC_045512.2 RefSeq CDS 27394 27759 . + 0 ID=cds-YP_009724395.1;Parent=gene-GU280_gp07;Dbxref=GenBank:YP_009724395.1,GeneID:43740573;Name=YP_009724395.1;gbkey=CDS;gene=ORF7a;locus_tag=GU280_gp07;product=ORF7a protein;protein_id=YP_009724395.1 +NC_045512.2 RefSeq gene 27756 27887 . + . ID=gene-GU280_gp08;Dbxref=GeneID:43740574;Name=ORF7b;gbkey=Gene;gene=ORF7b;gene_biotype=protein_coding;locus_tag=GU280_gp08 +NC_045512.2 RefSeq CDS 27756 27887 . + 0 ID=cds-YP_009725318.1;Parent=gene-GU280_gp08;Dbxref=GenBank:YP_009725318.1,GeneID:43740574;Name=YP_009725318.1;gbkey=CDS;gene=ORF7b;locus_tag=GU280_gp08;product=ORF7b;protein_id=YP_009725318.1 +NC_045512.2 RefSeq gene 27894 28259 . + . ID=gene-GU280_gp09;Dbxref=GeneID:43740577;Name=ORF8;gbkey=Gene;gene=ORF8;gene_biotype=protein_coding;locus_tag=GU280_gp09 +NC_045512.2 RefSeq CDS 27894 28259 . + 0 ID=cds-YP_009724396.1;Parent=gene-GU280_gp09;Dbxref=GenBank:YP_009724396.1,GeneID:43740577;Name=YP_009724396.1;gbkey=CDS;gene=ORF8;locus_tag=GU280_gp09;product=ORF8 protein;protein_id=YP_009724396.1 +NC_045512.2 RefSeq gene 28274 29533 . + . ID=gene-GU280_gp10;Dbxref=GeneID:43740575;Name=N;gbkey=Gene;gene=N;gene_biotype=protein_coding;locus_tag=GU280_gp10 +NC_045512.2 RefSeq CDS 28274 29533 . + 0 ID=cds-YP_009724397.2;Parent=gene-GU280_gp10;Dbxref=GenBank:YP_009724397.2,GeneID:43740575;Name=YP_009724397.2;Note=ORF9%3B structural protein;gbkey=CDS;gene=N;locus_tag=GU280_gp10;product=nucleocapsid phosphoprotein;protein_id=YP_009724397.2 +NC_045512.2 RefSeq gene 29558 29674 . + . ID=gene-GU280_gp11;Dbxref=GeneID:43740576;Name=ORF10;gbkey=Gene;gene=ORF10;gene_biotype=protein_coding;locus_tag=GU280_gp11 +NC_045512.2 RefSeq CDS 29558 29674 . + 0 ID=cds-YP_009725255.1;Parent=gene-GU280_gp11;Dbxref=GenBank:YP_009725255.1,GeneID:43740576;Name=YP_009725255.1;gbkey=CDS;gene=ORF10;locus_tag=GU280_gp11;product=ORF10 protein;protein_id=YP_009725255.1 +NC_045512.2 RefSeq stem_loop 29609 29644 . + . ID=id-GU280_gp11;Dbxref=GeneID:43740576;function=Coronavirus 3' UTR pseudoknot stem-loop 1;gbkey=stem_loop;gene=ORF10;inference=COORDINATES: profile::Rfam-release-14.1:RF00165%2CInfernal:1.1.2;locus_tag=GU280_gp11 +NC_045512.2 RefSeq stem_loop 29629 29657 . + . ID=id-GU280_gp11-2;Dbxref=GeneID:43740576;function=Coronavirus 3' UTR pseudoknot stem-loop 2;gbkey=stem_loop;gene=ORF10;inference=COORDINATES: profile::Rfam-release-14.1:RF00165%2CInfernal:1.1.2;locus_tag=GU280_gp11 +NC_045512.2 RefSeq three_prime_UTR 29675 29903 . + . ID=id-NC_045512.2:29675..29903;gbkey=3'UTR +NC_045512.2 RefSeq stem_loop 29728 29768 . + . ID=id-NC_045512.2:29728..29768;Note=basepair exception: alignment to the Rfam model implies coordinates 29740:29758 form a noncanonical C:T basepair%2C but the homologous positions form a highly conserved C:G basepair in other viruses%2C including SARS (NC_004718.3);function=Coronavirus 3' stem-loop II-like motif (s2m);gbkey=stem_loop;inference=COORDINATES: profile:Rfam-release-14.1:RF00164%2CInfernal:1.1.2 + diff --git a/example_data/example_mave_data/input/sample-01.vcf b/example_data/example_mave_data/input/sample-01.vcf new file mode 100644 index 0000000..dc45627 --- /dev/null +++ b/example_data/example_mave_data/input/sample-01.vcf @@ -0,0 +1,178 @@ +##fileformat=VCFv4.0 +##FILTER= +##fileDate=20240114 +##source=lofreq call --verbose --ref reference.fa --call-indels --min-cov 5 --max-depth 1000000 --min-bq 30 --min-alt-bq 30 --min-mq 20 --max-mq 255 --min-jq 0 --min-alt-jq 0 --def-alt-jq 0 --sig 0.0005 --bonf dynamic --no-default-filter --no-default-filter -r NC_045512.2:1-7475 -o /data/jwd05e/main/066/348/66348156/tmp/lofreq2_call_parallelrkr10tb5/0.vcf.gz reads.bam +##reference=reference.fa +##INFO= +##INFO= --min-bq among all bases at the site"> +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##INFO= +##bcftools_annotateVersion=1.10.2+htslib-1.10.2 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites -AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 21:40:22 2024 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites +AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 21:41:43 2024 +##SnpEffVersion="4.5covid19 (build 2020-04-15 22:26), by Pablo Cingolani" +##SnpEffCmd="SnpEff -i vcf -o vcf -formatEff -classic -no-downstream -no-intergenic -no-upstream -stats /data/jwd02f/main/066/348/66348336/outputs/dataset_cb0da566-f404-406c-8750-a0188611194c.dat NC_045512.2 /data/dnb09/galaxy_db/files/4/6/1/dataset_46129f47-0e63-4f5e-91c9-d735e0b3c0be.dat " +##INFO= +##INFO= +##INFO= +##FILTER= 0.001000"> +##SnpSiftVersion="SnpSift 4.3t (build 2017-11-24 10:18), by Pablo Cingolani" +##SnpSiftCmd="SnpSift Filter -f /data/dnb09/galaxy_db/files/b/c/0/dataset_bc06cf4c-aa70-4789-8c22-b48bbd13a818.dat -e /data/jwd02f/main/066/348/66348991/configs/tmpurq0al3z" +##FILTER== 1"> +##SnpSiftCmd="SnpSift Filter -f /data/dnb09/galaxy_db/files/2/0/8/dataset_208f366a-bd21-41f6-988d-1c2caf4f46fc.dat -e /data/jwd02f/main/066/349/66349010/configs/tmpy2zr42h8 --addFilter min_af_0.05Xmin_dp_1Xmin_dp_alt_10" +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO +NC_045512.2 241 . C T 49314.0 PASS DP=2586;AF=0.939288;SB=0;DP4=2,2,1277,1302 +NC_045512.2 443 . GT G 146.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3080;AF=0.003247;SB=0;DP4=1580,1487,5,5;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttg/|L61|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 507 . ATGGTCATGTTATGGT A 657.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3703;AF=0.009182;SB=0;DP4=1830,1839,16,18;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 509 . GGTCATGTTATGGTT G 920.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3697;AF=0.012443;SB=0;DP4=1816,1829,23,23;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 509 . GGTCATGTTA G 96.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3697;AF=0.002164;SB=0;DP4=1816,1829,4,4;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G) +NC_045512.2 509 . GGTCATGTT G 103.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3697;AF=0.002164;SB=0;DP4=1816,1829,4,4;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 514 . TGTTATG T 261.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3689;AF=0.004337;SB=0;DP4=1828,1845,8,8;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||atggtt/|MV85|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||atggtt/|MV85|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME) +NC_045512.2 515 . GTTATGGTT G 157.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3684;AF=0.002986;SB=0;DP4=1835,1851,5,6;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||gttatggtt/|VMV84|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),FRAME_SHIFT(HIGH||gttatggtt/|VMV84|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||gttatggtt/|VMV84|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||gttatggtt/|VMV84|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 517 . TATG T 255.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3653;AF=0.00438;SB=0;DP4=1810,1828,8,8;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||atg/|M85|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),CODON_DELETION(MODERATE||atg/|M85|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_DELETION(MODERATE||atg/|M85|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_DELETION(MODERATE||atg/|M85|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T) +NC_045512.2 517 . TA T 73.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3653;AF=0.001642;SB=0;DP4=1810,1828,3,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||atg/|M85|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),FRAME_SHIFT(HIGH||atg/|M85|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||atg/|M85|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||atg/|M85|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 518 . ATGGTT A 215.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3597;AF=0.003892;SB=0;DP4=1811,1830,7,7;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||atggtt/|MV85|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),FRAME_SHIFT(HIGH||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||atggtt/|MV85|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 683 . CTA C 67.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2886;AF=0.001733;SB=1;DP4=1426,1491,3,2;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||cta/|L140|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),FRAME_SHIFT(HIGH||cta/|L140|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|C|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||cta/|L140|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|C|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||cta/|L140|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 831 . A C 90.0 sb_fdr;min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2479;AF=0.00363;SB=177;DP4=1249,1162,0,57;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAc/aCc|N189T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAc/aCc|N189T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAc/aCc|N9T|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAc/aCc|N9T|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2164 . G C 49314.0 PASS DP=3347;AF=0.668061;SB=1;DP4=393,462,1157,1322;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E633D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E633D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E453D|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E453D|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2330 . T A 301.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=810;AF=0.023457;SB=5;DP4=304,456,13,12;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2832 . A G 7707.0 PASS DP=1876;AF=0.160981;SB=6;DP4=711,835,138,189;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3037 . C T 49314.0 PASS DP=2001;AF=0.913043;SB=0;DP4=0,1,949,1037;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3545 . AATG A 151.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2384;AF=0.004195;SB=0;DP4=1192,1186,5,5;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aatgga/aga|NG1094R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aatgga/aga|NG1094R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aatgga/aga|NG276R|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aatgga/aga|NG276R|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 4148 . GT G 79.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1215;AF=0.004115;SB=0;DP4=605,605,3,2;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tta/|L1296|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L1296|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L478|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L478|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 4758 . A T 93.0 sb_fdr;min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2275;AF=0.003956;SB=105;DP4=1097,1134,40,1;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gTa|E1498V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gTa|E1498V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gTa|E680V|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gTa|E680V|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 4890 . C A 81.0 sb_fdr;min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2254;AF=0.003549;SB=59;DP4=1073,1134,1,25;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aAc|T1542N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aAc|T1542N|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aAc|T724N|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aAc|T724N|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5386 . T G 5780.0 PASS DP=2544;AF=0.096305;SB=0;DP4=1111,1133,142,147;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5743 . G C 1702.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2671;AF=0.037439;SB=4;DP4=1280,1252,59,69;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5744 . T C 1921.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2668;AF=0.041229;SB=3;DP4=1262,1265,71,61;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5816 . GCTTTA G 90.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2309;AF=0.002599;SB=0;DP4=1160,1147,3,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||ttactt/|LL1852|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttactt/|LL1852|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttactt/|LL1034|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttactt/|LL1034|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 6027 . C T 45861.0 PASS DP=1941;AF=0.68882;SB=1;DP4=243,242,734,708;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCa/cTa|P1921L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCa/cTa|P1921L|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCa/cTa|P1103L|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCa/cTa|P1103L|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6512 . AGTT A 4047.0 PASS DP=2170;AF=0.071429;SB=0;DP4=1038,977,80,75;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6696 . C CT 66.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2254;AF=0.002218;SB=1;DP4=1145,1154,3,2;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ctt/Tctt|L2146S?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L2146S?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L1328S?|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L1328S?|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 7432 . ATT A 88.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1865;AF=0.003217;SB=0;DP4=906,963,3,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttttat/|FY2390|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttttat/|FY2390|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttttat/|FY1572|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttttat/|FY1572|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 8376 . CA C 180.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1683;AF=0.006536;SB=0;DP4=921,751,6,5;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||agt/|S2706|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||agt/|S2706|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||agt/|S1888|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||agt/|S1888|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 8393 . G A 5071.0 PASS DP=2008;AF=0.106076;SB=2;DP4=978,795,124,109;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 8620 . T C 7394.0 PASS DP=2556;AF=0.119327;SB=3;DP4=1028,1183,163,172;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcT/gcC|A2785|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcC|A2785|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcC|A22|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcC|A22|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 9498 . T C 47065.0 PASS DP=1981;AF=0.705199;SB=0;DP4=203,182,828,755;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTt/gCt|V3078A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTt/gCt|V3078A|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTt/gCt|V315A|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTt/gCt|V315A|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 9621 . A T 87.0 sb_fdr;min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2834;AF=0.003176;SB=97;DP4=1354,1410,51,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gTt|D3119V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gTt|D3119V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gTt|D356V|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gTt|D356V|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10029 . C T 3418.0 PASS DP=2616;AF=0.063838;SB=0;DP4=1207,1211,98,97;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10449 . C A 6386.0 PASS DP=2901;AF=0.096863;SB=3;DP4=1275,1287,154,170;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10484 . T G 89.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2282;AF=0.003944;SB=2;DP4=1221,1041,9,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11083 . G T 102.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2731;AF=0.004028;SB=37;DP4=1377,1307,35,9;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|ttG/ttT|L3606F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|ttG/ttT|L3606F|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|ttG/ttT|L37F|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|ttG/ttT|L37F|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11282 . AGTTTGTCTG A 6418.0 PASS DP=3007;AF=0.077486;SB=0;DP4=1309,1464,110,123;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 11537 . A G 7226.0 PASS DP=3602;AF=0.089395;SB=2;DP4=1588,1634,174,192;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11625 . G T 79.0 sb_fdr;min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2400;AF=0.003333;SB=124;DP4=1055,1300,40,1;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGc/gTc|G3787V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGc/gTc|G3787V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGc/gTc|G218V|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGc/gTc|G218V|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13195 . T C 10130.0 PASS DP=4311;AF=0.101833;SB=8;DP4=2013,1803,275,213;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13728 . TGCTA T 125.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2026;AF=0.003949;SB=0;DP4=1039,1031,4,4;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||gctaaa/|AK4489|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),FRAME_SHIFT(HIGH||gctaaa/|AK97|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 13914 . TA T 103.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2937;AF=0.002724;SB=0;DP4=1472,1457,4,4;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aag/|K4552|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K160|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 14407 . CCTACAAG C 129.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1836;AF=0.004357;SB=0;DP4=963,910,4,4;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||cctacaagt/|PTS4715|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),FRAME_SHIFT(HIGH||cctacaagt/|PTS323|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 14408 . C T 49314.0 PASS DP=1836;AF=0.915033;SB=0;DP4=0,0,940,883;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P4715L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P323L|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 14852 . TTGTA T 77.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1755;AF=0.002849;SB=1;DP4=875,878,3,2;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||tttgta/|FV4863|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),FRAME_SHIFT(HIGH||tttgta/|FV471|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 14854 . GTA G 95.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1727;AF=0.003474;SB=0;DP4=864,867,3,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||gta/|V4864|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),FRAME_SHIFT(HIGH||gta/|V472|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|G|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 15021 . TTTCGCATATACAAAACGTA T 93.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2043;AF=0.002937;SB=0;DP4=1073,974,3,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttcgcatatacaaaacgtaat/|FAYTKRN4920|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),FRAME_SHIFT(HIGH||ttcgcatatacaaaacgtaat/|FAYTKRN528|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 15157 . C A 189.0 sb_fdr DP=2238;AF=0.006702;SB=941;DP4=1154,811,0,271;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Aaa|Q4965K|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Aaa|Q573K|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15173 . C A 100.0 sb_fdr;min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2293;AF=0.003925;SB=611;DP4=1167,919,2,196;EFF=STOP_GAINED(HIGH|NONSENSE|tCa/tAa|S4970*|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),STOP_GAINED(HIGH|NONSENSE|tCa/tAa|S578*|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15240 . C T 3970.0 PASS DP=2493;AF=0.074208;SB=0;DP4=1086,1199,94,102;EFF=SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N4992|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N600|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15455 . C T 85.0 sb_fdr;min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1166;AF=0.006003;SB=362;DP4=450,602,106,0;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCa/tTa|S5064L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCa/tTa|S672L|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15479 . C A 90.0 sb_fdr;min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1113;AF=0.006289;SB=245;DP4=422,592,90,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aAc|T5072N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aAc|T680N|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15781 . A T 89.0 sb_fdr;min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2559;AF=0.003517;SB=94;DP4=1210,1289,47,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aac/Tac|N5173Y|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aac/Tac|N781Y|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 16154 . T C 17668.0 PASS DP=5623;AF=0.129646;SB=6;DP4=2347,2447,411,391;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTt/gCt|V5297A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTt/gCt|V905A|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 16946 . C T 49314.0 PASS DP=3389;AF=0.712305;SB=1;DP4=388,383,1295,1316;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCa/gTa|A5561V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCa/gTa|A237V|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 17766 . CT C 81.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3045;AF=0.00197;SB=0;DP4=1532,1511,3,3;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||ttt/|F5835|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F511|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 17938 . G A 5468.0 PASS DP=1729;AF=0.127241;SB=1;DP4=707,785,107,126;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gca/Aca|A5892T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gca/Aca|A568T|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18149 . G T 174.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1490;AF=0.008725;SB=3;DP4=722,740,9,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGt/gTt|G5962V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGt/gTt|G37V|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18163 . A G 3446.0 PASS DP=1464;AF=0.099727;SB=0;DP4=638,656,82,83;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I5967V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I42V|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18742 . TACGTCTA T 86.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2353;AF=0.00255;SB=0;DP4=1179,1172,3,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||tacgtctat/|YVY6160|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),FRAME_SHIFT(HIGH||tacgtctat/|YVY235|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 19517 . TGTA T 71.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2081;AF=0.002403;SB=1;DP4=1081,1044,2,3;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtat/ttt|LY6418F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtat/ttt|LY493F|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 20117 . C A 97.0 sb_fdr;min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1514;AF=0.005284;SB=134;DP4=741,705,4,60;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T6618K|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T166K|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 20268 . A G 49314.0 PASS DP=2298;AF=0.827241;SB=0;DP4=110,109,1034,1038;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttA/ttG|L6668|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),SYNONYMOUS_CODING(LOW|SILENT|ttA/ttG|L216|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 21575 . C T 145.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2936;AF=0.005109;SB=38;DP4=1406,1477,31,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L5F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21735 . TC T 1172.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2410;AF=0.023651;SB=0;DP4=1172,1181,29,28;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||ttc/|F58|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21736 . C CT 138.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2412;AF=0.01534;SB=3;DP4=1181,1193,21,16;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tcc/tTcc|S60F?|1273|S|protein_coding|CODING|GU280_gp02|1|CT|INFO_REALIGN_3_PRIME) +NC_045512.2 21736 . C T 49314.0 PASS DP=2412;AF=0.659619;SB=0;DP4=309,315,861,865;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F58|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21740 . TCCAATGTTACTTGGTTCCATGCTATACATGTCTCTGGGA T 127.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2378;AF=0.003364;SB=0;DP4=1188,1200,4,4;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttacttggttccatgctatacatgtctctgggaccaatggt/ggt|VTWFHAIHVSGTNG62G|1273|S|protein_coding|CODING|GU280_gp02|1|T|INFO_REALIGN_3_PRIME) +NC_045512.2 21762 . C T 3568.0 PASS DP=2536;AF=0.067429;SB=1;DP4=1156,1179,92,99;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A67V|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21764 . ATACATG A 4746.0 PASS DP=2467;AF=0.072558;SB=1;DP4=1135,1153,86,93;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||atacatgtc/atc|IHV68I|1273|S|protein_coding|CODING|GU280_gp02|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 21846 . C T 7112.0 PASS DP=1795;AF=0.154318;SB=1;DP4=708,785,147,154;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T95I|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21890 . TTA T 77.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1489;AF=0.003358;SB=0;DP4=716,783,2,3;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||tta/|L110|1273|S|protein_coding|CODING|GU280_gp02|1|T);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 21986 . GGTGTTTATT G 3906.0 PASS DP=1232;AF=0.119318;SB=1;DP4=562,525,73,74;INDEL;HRUN=3;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtgtttattac/gac|GVYY142D|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 22193 . AATT A 2168.0 PASS DP=1551;AF=0.055448;SB=3;DP4=744,863,44,42;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattta/ata|NL211I|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22204 . T TGAGCCAGAA 1932.0 PASS DP=1279;AF=0.059421;SB=3;DP4=578,622,40,36;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGAAGAt|D215EPED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22578 . G A 6222.0 PASS DP=2755;AF=0.098004;SB=6;DP4=1247,1208,140,158;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGt/gAt|G339D|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22583 . GT G 74.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2721;AF=0.002205;SB=0;DP4=1374,1357,3,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||ttt/|F342|1273|S|protein_coding|CODING|GU280_gp02|1|G|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 22583 . GTT G 90.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2721;AF=0.002573;SB=0;DP4=1374,1357,4,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||ttt/|F342|1273|S|protein_coding|CODING|GU280_gp02|1|G|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 22673 . T C 2644.0 PASS DP=1786;AF=0.069429;SB=11;DP4=791,849,55,82;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tcc/Ccc|S371P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22674 . C T 2569.0 PASS DP=1617;AF=0.074212;SB=2;DP4=607,850,63,79;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S371F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22679 . T C 3086.0 PASS DP=1585;AF=0.085804;SB=0;DP4=608,820,61,86;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Cca|S373P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22686 . C T 3049.0 PASS DP=1584;AF=0.084596;SB=0;DP4=595,844,58,86;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S375F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22992 . G A 4087.0 PASS DP=1827;AF=0.103448;SB=13;DP4=803,809,121,90;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGc/aAc|S477N|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22995 . C A 4203.0 PASS DP=1785;AF=0.103641;SB=13;DP4=781,785,122,91;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T478K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23013 . A C 8000.0 PASS DP=1827;AF=0.16913;SB=5;DP4=785,695,191,148;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gCa|E484A|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23040 . A G 7782.0 PASS DP=1831;AF=0.162206;SB=0;DP4=795,705,173,150;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q493R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23048 . G A 8816.0 PASS DP=1974;AF=0.168693;SB=0;DP4=850,760,189,164;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G496S|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23055 . A G 8046.0 PASS DP=2039;AF=0.155468;SB=0;DP4=869,784,196,177;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q498R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23063 . A T 10122.0 PASS DP=2415;AF=0.163561;SB=0;DP4=1064,941,220,189;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aat/Tat|N501Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23075 . T C 8442.0 PASS DP=2408;AF=0.142442;SB=0;DP4=1059,940,217,190;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y505H|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23202 . C A 11348.0 PASS DP=3160;AF=0.143038;SB=0;DP4=1319,1338,242,251;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T547K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23403 . A G 49314.0 PASS DP=4080;AF=0.888235;SB=2;DP4=6,4,2017,2036;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D614G|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23525 . C T 12646.0 PASS DP=3508;AF=0.147092;SB=0;DP4=1395,1546,266,292;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cat/Tat|H655Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23554 . ACCCATTGGTGCAGGTATATGCGCTAGTT A 102.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2819;AF=0.002483;SB=3;DP4=1312,1532,2,5;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||cccattggtgcaggtatatgcgctagttat/|PIGAGICASY665|1273|S|protein_coding|CODING|GU280_gp02|1|A);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 23563 . T G 85.0 sb_fdr;min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2470;AF=0.003644;SB=179;DP4=1056,1306,67,4;EFF=SYNONYMOUS_CODING(LOW|SILENT|ggT/ggG|G667|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23568 . GTA G 183.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2419;AF=0.004547;SB=0;DP4=1112,1303,5,6;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||atatgc/|IC670|1273|S|protein_coding|CODING|GU280_gp02|1|G|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 23599 . T G 11508.0 PASS DP=2113;AF=0.207761;SB=3;DP4=755,850,226,276;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaG|N679K|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23604 . C A 6944.0 PASS DP=1776;AF=0.156532;SB=4;DP4=682,782,131,169;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cAt|P681H|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23948 . G T 3413.0 PASS DP=1381;AF=0.1021;SB=0;DP4=644,566,82,72;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gat/Tat|D796Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24025 . ACTT A 111.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1760;AF=0.003977;SB=0;DP4=877,876,4,3;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||ctt/|L822|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24130 . C A 4441.0 PASS DP=1541;AF=0.121999;SB=4;DP4=608,716,89,120;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaC/aaA|N856K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24195 . TA T 89.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1980;AF=0.00303;SB=0;DP4=1017,957,3,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||tta/|L878|1273|S|protein_coding|CODING|GU280_gp02|1|T);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 24424 . A T 9980.0 PASS DP=2405;AF=0.166736;SB=4;DP4=976,990,226,209;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caT|Q954H|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24469 . T A 7685.0 PASS DP=3251;AF=0.101507;SB=1;DP4=1430,1456,180,177;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N969K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24503 . C T 8963.0 PASS DP=3365;AF=0.111738;SB=1;DP4=1422,1533,190,213;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L981F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24942 . A T 126.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1776;AF=0.006757;SB=2;DP4=879,876,10,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gTt|D1127V|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25000 . C T 5496.0 PASS DP=1468;AF=0.155995;SB=0;DP4=597,600,130,128;EFF=SYNONYMOUS_CODING(LOW|SILENT|gaC/gaT|D1146|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25584 . C T 10776.0 PASS DP=2554;AF=0.164056;SB=0;DP4=1042,1054,222,227;EFF=SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T64|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 26144 . G A 5571.0 PASS DP=2938;AF=0.085092;SB=1;DP4=1267,1329,145,146;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGt/gAt|G251D|275|ORF3a|protein_coding|CODING|GU280_gp03|1|A) +NC_045512.2 26194 . A T 98.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2862;AF=0.003843;SB=0;DP4=1395,1420,8,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Acg/Tcg|T268S|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 26270 . C T 8205.0 PASS DP=2423;AF=0.135782;SB=1;DP4=950,1103,162,199;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aTa|T9I|75|E|protein_coding|CODING|GU280_gp04|1|T) +NC_045512.2 26283 . AGTT A 63.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3361;AF=0.001488;SB=1;DP4=1647,1709,3,2;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||gtt/|V14|75|E|protein_coding|CODING|GU280_gp04|1|A) +NC_045512.2 26493 . G GT 66.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1929;AF=0.002592;SB=0;DP4=944,997,2,3;INDEL;HRUN=5 +NC_045512.2 26530 . A G 260.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1814;AF=0.010474;SB=3;DP4=850,922,14,10;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D3G|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26649 . A T 82.0 sb_fdr;min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2050;AF=0.003902;SB=135;DP4=1040,954,49,0;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aat/Tat|N43Y|222|M|protein_coding|CODING|GU280_gp05|1|T) +NC_045512.2 26709 . G A 99.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2598;AF=0.003849;SB=0;DP4=1244,1294,6,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A63T|222|M|protein_coding|CODING|GU280_gp05|1|A) +NC_045512.2 26779 . GTCTTGTAGGCTTGATGTGGCTCAGCTACTTCATTGCT G 807.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2783;AF=0.013654;SB=1;DP4=1290,1455,19,19;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||gtaggcttgatgtggctcagctacttcattgcttctttc/|VGLMWLSYFIASF88|222|M|protein_coding|CODING|GU280_gp05|1|G|INFO_REALIGN_3_PRIME);LOF=(M|GU280_gp05|1|1.00) +NC_045512.2 26784 . GTAGGCTTGATGTGGCTCAGCTACTTCATTGCTTCTT G 105.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2641;AF=0.002651;SB=3;DP4=1235,1405,2,5;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gtaggcttgatgtggctcagctacttcattgcttctttc/gtc|VGLMWLSYFIASF88V|222|M|protein_coding|CODING|GU280_gp05|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 26786 . AGGCTTGATGTGGCTCAGCTACTTCATTGCTTCTT A 162.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2629;AF=0.003804;SB=0;DP4=1224,1401,5,5;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggcttgatgtggctcagctacttcattgcttctttc/|GLMWLSYFIASF89|222|M|protein_coding|CODING|GU280_gp05|1|A);LOF=(M|GU280_gp05|1|1.00) +NC_045512.2 27131 . CTA C 82.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2815;AF=0.002131;SB=0;DP4=1382,1429,3,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||tataaa/|YK204|222|M|protein_coding|CODING|GU280_gp05|1|C|INFO_REALIGN_3_PRIME);LOF=(M|GU280_gp05|1|1.00) +NC_045512.2 27131 . CTATAAAT C 66.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2879;AF=0.001737;SB=1;DP4=1441,1434,2,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||tataaatta/|YKL204|222|M|protein_coding|CODING|GU280_gp05|1|C|INFO_REALIGN_3_PRIME);LOF=(M|GU280_gp05|1|1.00) +NC_045512.2 27133 . ATAAATT A 83.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2813;AF=0.002133;SB=1;DP4=1382,1429,2,4;INDEL;HRUN=1;EFF=STOP_GAINED+CODON_CHANGE_PLUS_CODON_DELETION(HIGH||tataaatta/taa|YKL204*|222|M|protein_coding|CODING|GU280_gp05|1|A) +NC_045512.2 27190 . AAGTGACAACAGATGTTTCATCTCGTTGACTT A 78.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3646;AF=0.001646;SB=0;DP4=1860,1794,3,3;INDEL;HRUN=2;EFF=GENE_FUSION(HIGH|||||M+ORF6||CODING|||A),FRAME_SHIFT+STOP_LOST+SPLICE_SITE_REGION(HIGH||taa/|*223|222|M|protein_coding|CODING|GU280_gp05|1|A),FRAME_SHIFT+START_LOST(HIGH||atgtttcatctcgttgacttt/|MFHLVDF1|61|ORF6|protein_coding|CODING|GU280_gp06|1|A);LOF=(ORF6|GU280_gp06|1|1.00) +NC_045512.2 27213 . C T 696.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3568;AF=0.013453;SB=2;DP4=1776,1708,27,31;EFF=SYNONYMOUS_CODING(LOW|SILENT|ctC/ctT|L4|61|ORF6|protein_coding|CODING|GU280_gp06|1|T) +NC_045512.2 27259 . A C 4789.0 PASS DP=2095;AF=0.09642;SB=1;DP4=991,861,123,114;EFF=SYNONYMOUS_CODING(LOW|SILENT|Agg/Cgg|R20|61|ORF6|protein_coding|CODING|GU280_gp06|1|C) +NC_045512.2 27382 . G C 5593.0 PASS DP=3415;AF=0.073499;SB=0;DP4=1558,1566,137,142;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gat/Cat|D61H|61|ORF6|protein_coding|CODING|GU280_gp06|1|C) +NC_045512.2 27383 . A T 5412.0 PASS DP=3410;AF=0.071554;SB=0;DP4=1558,1555,138,139;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gTt|D61V|61|ORF6|protein_coding|CODING|GU280_gp06|1|T) +NC_045512.2 27384 . T C 5537.0 PASS DP=3424;AF=0.073598;SB=0;DP4=1562,1567,142,145;EFF=SYNONYMOUS_CODING(LOW|SILENT|gaT/gaC|D61|61|ORF6|protein_coding|CODING|GU280_gp06|1|C) +NC_045512.2 27753 . A C 49314.0 PASS DP=2359;AF=0.690123;SB=0;DP4=279,274,914,887;EFF=SYNONYMOUS_CODING(LOW|SILENT|acA/acC|T120|121|ORF7a|protein_coding|CODING|GU280_gp07|1|C) +NC_045512.2 27807 . C T 8827.0 PASS DP=2560;AF=0.141406;SB=0;DP4=1058,1099,196,201;EFF=SYNONYMOUS_CODING(LOW|SILENT|Cta/Tta|L18|43|ORF7b|protein_coding|CODING|GU280_gp08|1|T) +NC_045512.2 28271 . A T 11174.0 PASS DP=3057;AF=0.145895;SB=0;DP4=1261,1299,236,243 +NC_045512.2 28311 . C T 10614.0 PASS DP=3165;AF=0.138073;SB=1;DP4=1261,1370,246,259;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cTc|P13L|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28361 . GGAGAACGCA G 6660.0 PASS DP=3198;AF=0.080363;SB=1;DP4=1401,1547,126,131;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggagaacgcagt/ggt|GERS30G|419|N|protein_coding|CODING|GU280_gp10|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 28370 . A G 397.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2962;AF=0.012829;SB=7;DP4=1264,1378,31,23;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Agt/Ggt|S33G|419|N|protein_coding|CODING|GU280_gp10|1|G) +NC_045512.2 28854 . C T 49314.0 PASS DP=5231;AF=0.630663;SB=2;DP4=773,886,1694,1864;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCa/tTa|S194L|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28881 . G A 1190.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=4804;AF=0.016861;SB=1;DP4=2192,2513,48,50;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGg/aAg|R203K|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28882 . G A 1089.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=4764;AF=0.015953;SB=3;DP4=2163,2494,47,45;EFF=SYNONYMOUS_CODING(LOW|SILENT|agG/agA|R203|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28883 . G C 1049.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=4749;AF=0.016214;SB=1;DP4=2173,2445,43,53;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gga/Cga|G204R|419|N|protein_coding|CODING|GU280_gp10|1|C) +NC_045512.2 28981 . T G 97.0 sb_fdr DP=2932;AF=0.003411;SB=811;DP4=1186,1466,256,1;EFF=SYNONYMOUS_CODING(LOW|SILENT|ggT/ggG|G236|419|N|protein_coding|CODING|GU280_gp10|1|G) +NC_045512.2 28987 . CCAA C 100.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2935;AF=0.002385;SB=0;DP4=1469,1494,3,4;INDEL;HRUN=2;EFF=CODON_DELETION(MODERATE||caa/|Q242|419|N|protein_coding|CODING|GU280_gp10|1|C|INFO_REALIGN_3_PRIME) +NC_045512.2 29623 . T C 14384.0 PASS DP=978;AF=0.473415;SB=0;DP4=233,236,255,249;EFF=SYNONYMOUS_CODING(LOW|SILENT|aaT/aaC|N22|38|ORF10|protein_coding|CODING|GU280_gp11|1|C) +NC_045512.2 29719 . C T 979.0 PASS DP=984;AF=0.049797;SB=0;DP4=459,470,25,27 +NC_045512.2 29736 . G T 13283.0 PASS DP=951;AF=0.453207;SB=0;DP4=238,241,230,241 diff --git a/example_data/example_mave_data/input/sample-02.vcf b/example_data/example_mave_data/input/sample-02.vcf new file mode 100644 index 0000000..4e38980 --- /dev/null +++ b/example_data/example_mave_data/input/sample-02.vcf @@ -0,0 +1,245 @@ +##fileformat=VCFv4.0 +##FILTER= +##fileDate=20240114 +##source=lofreq call --verbose --ref reference.fa --call-indels --min-cov 5 --max-depth 1000000 --min-bq 30 --min-alt-bq 30 --min-mq 20 --max-mq 255 --min-jq 0 --min-alt-jq 0 --def-alt-jq 0 --sig 0.0005 --bonf dynamic --no-default-filter --no-default-filter -r NC_045512.2:1-7475 -o /data/jwd02f/main/066/348/66348157/tmp/lofreq2_call_parallelseq_lia6/0.vcf.gz reads.bam +##reference=reference.fa +##INFO= +##INFO= --min-bq among all bases at the site"> +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##INFO= +##bcftools_annotateVersion=1.10.2+htslib-1.10.2 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites -AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 20:36:55 2024 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites +AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 20:38:21 2024 +##SnpEffVersion="4.5covid19 (build 2020-04-15 22:26), by Pablo Cingolani" +##SnpEffCmd="SnpEff -i vcf -o vcf -formatEff -classic -no-downstream -no-intergenic -no-upstream -stats /data/jwd05e/main/066/348/66348337/outputs/dataset_c288c94a-0348-41f7-b870-1606f9e31660.dat NC_045512.2 /data/dnb09/galaxy_db/files/7/7/2/dataset_772d0911-b66c-4438-8ce9-5422d2ce0169.dat " +##INFO= +##INFO= +##INFO= +##FILTER= 0.001000"> +##SnpSiftVersion="SnpSift 4.3t (build 2017-11-24 10:18), by Pablo Cingolani" +##SnpSiftCmd="SnpSift Filter -f /data/dnb09/galaxy_db/files/b/e/1/dataset_be17d1cf-1b65-49e1-8faa-ce584dae98c1.dat -e /data/jwd02f/main/066/348/66348992/configs/tmp4t__jjl5" +##FILTER== 1"> +##SnpSiftCmd="SnpSift Filter -f /data/dnb09/galaxy_db/files/c/3/7/dataset_c371141d-e70d-4f7b-9ec8-cac242098745.dat -e /data/jwd05e/main/066/349/66349011/configs/tmp_zqshhmt --addFilter min_af_0.05Xmin_dp_1Xmin_dp_alt_10" +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO +NC_045512.2 241 . C T 10937.0 PASS DP=328;AF=0.902439;SB=0;DP4=0,0,164,164 +NC_045512.2 507 . ATGGTCATGTTATGGT A 412.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2144;AF=0.009795;SB=0;DP4=1058,1065,10,11;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 509 . GGTCATGTT G 351.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2126;AF=0.009407;SB=0;DP4=1025,1032,10,10;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 509 . GGTCATGTTA G 840.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2126;AF=0.018815;SB=0;DP4=1025,1032,20,20;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G) +NC_045512.2 509 . GGTCATGTTATGGTT G 504.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2126;AF=0.011759;SB=0;DP4=1025,1032,12,13;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 513 . ATGTTATGGT A 92.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2104;AF=0.002852;SB=0;DP4=1045,1055,3,3;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttatggttgag/gag|VMVE84E|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttatggttgag/gag|VMVE84E|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttatggttgag/gag|VMVE84E|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttatggttgag/gag|VMVE84E|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 514 . TGTTATG T 191.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2135;AF=0.005152;SB=0;DP4=1057,1068,5,6;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||atggtt/|MV85|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||atggtt/|MV85|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME) +NC_045512.2 515 . GTTA G 111.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2138;AF=0.003274;SB=0;DP4=1059,1070,3,4;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttatg/gtg|VM84V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttatg/gtg|VM84V|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttatg/gtg|VM84V|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttatg/gtg|VM84V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 517 . TA T 130.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2124;AF=0.003766;SB=0;DP4=1052,1064,4,4;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||atg/|M85|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),FRAME_SHIFT(HIGH||atg/|M85|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||atg/|M85|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||atg/|M85|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 518 . ATGGTT A 435.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2082;AF=0.010567;SB=0;DP4=1046,1057,11,11;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||atggtt/|MV85|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),FRAME_SHIFT(HIGH||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||atggtt/|MV85|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 671 . TACGGCGCCGATCTA T 120.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1488;AF=0.004704;SB=0;DP4=715,775,3,4;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||tacggcgccgatctaaag/|YGADLK136|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tacggcgccgatctaaag/|YGADLK136|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tacggcgccgatctaaag/|YGADLK136|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tacggcgccgatctaaag/|YGADLK136|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 1026 . C CT 82.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1146;AF=0.004363;SB=0;DP4=607,534,3,2;INDEL;HRUN=4;EFF=FRAME_SHIFT+STOP_GAINED(HIGH||gaa/Tgaa|E256*?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT+STOP_GAINED(HIGH||gaa/Tgaa|E256*?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT+STOP_GAINED(HIGH||gaa/Tgaa|E76*?|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT+STOP_GAINED(HIGH||gaa/Tgaa|E76*?|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14);NMD=(ORF1ab|GU280_gp01|28|0.04) +NC_045512.2 1800 . CA C 64.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1008;AF=0.003968;SB=0;DP4=497,509,2,2;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||aaa/|K513|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K513|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K333|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K333|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 1983 . T A 100.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2702;AF=0.003701;SB=0;DP4=1355,1329,5,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTt/aAt|I573N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTt/aAt|I573N|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTt/aAt|I393N|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTt/aAt|I393N|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2007 . T C 135.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2927;AF=0.004441;SB=0;DP4=1454,1448,7,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTt/aCt|I581T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTt/aCt|I581T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTt/aCt|I401T|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTt/aCt|I401T|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2330 . T A 218.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=781;AF=0.016645;SB=0;DP4=360,384,7,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2621 . A T 91.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1643;AF=0.004869;SB=0;DP4=824,802,5,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aac/Tac|N786Y|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aac/Tac|N786Y|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aac/Tac|N606Y|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aac/Tac|N606Y|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2832 . A G 35943.0 PASS DP=1069;AF=0.910196;SB=3;DP4=1,0,491,575;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3037 . C T 5436.0 PASS DP=153;AF=0.947712;SB=0;DP4=0,0,75,78;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3104 . T A 183.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=507;AF=0.021696;SB=0;DP4=263,230,8,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tat/Aat|Y947N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tat/Aat|Y947N|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tat/Aat|Y129N|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tat/Aat|Y129N|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3530 . GATTACATAGCTACTAATGGACCACTTAAAGTGGGTGGTAGTTGTGTTT G 170.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1296;AF=0.006944;SB=0;DP4=660,639,5,4;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gattacatagctactaatggaccacttaaagtgggtggtagttgtgtttta/gta|DYIATNGPLKVGGSCVL1089V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gattacatagctactaatggaccacttaaagtgggtggtagttgtgtttta/gta|DYIATNGPLKVGGSCVL1089V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gattacatagctactaatggaccacttaaagtgggtggtagttgtgtttta/gta|DYIATNGPLKVGGSCVL271V|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gattacatagctactaatggaccacttaaagtgggtggtagttgtgtttta/gta|DYIATNGPLKVGGSCVL271V|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3604 . CTG C 135.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1451;AF=0.005513;SB=0;DP4=747,750,4,4;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||tgt/|C1114|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgt/|C1114|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgt/|C296|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgt/|C296|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 3876 . C T 92.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=54;AF=0.074074;SB=0;DP4=25,23,2,2;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A1204V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A1204V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A386V|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A386V|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 4240 . T C 119.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=524;AF=0.015267;SB=0;DP4=255,256,4,4;EFF=SYNONYMOUS_CODING(LOW|SILENT|taT/taC|Y1325|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|taT/taC|Y1325|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|taT/taC|Y507|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|taT/taC|Y507|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 4528 . ATT A 67.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=748;AF=0.005348;SB=0;DP4=370,372,2,2;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttttac/|FY1422|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttttac/|FY1422|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttttac/|FY604|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttttac/|FY604|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 4531 . TTACTTTTACACCAGTAAAACAACTG T 75.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=724;AF=0.005525;SB=0;DP4=359,361,2,2;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tacttttacaccagtaaaacaactgta/|YFYTSKTTV1423|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tacttttacaccagtaaaacaactgta/|YFYTSKTTV1423|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tacttttacaccagtaaaacaactgta/|YFYTSKTTV605|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tacttttacaccagtaaaacaactgta/|YFYTSKTTV605|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 4576 . A T 110.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=780;AF=0.010256;SB=2;DP4=371,396,7,5;EFF=SYNONYMOUS_CODING(LOW|SILENT|acA/acT|T1437|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|acA/acT|T1437|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|acA/acT|T619|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|acA/acT|T619|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 4578 . TTAACGATC T 73.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=774;AF=0.005168;SB=0;DP4=373,397,2,2;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||aacgatctaaat/|NDLN1439|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aacgatctaaat/|NDLN1439|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aacgatctaaat/|NDLN621|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aacgatctaaat/|NDLN621|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 4579 . T A 116.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=775;AF=0.010323;SB=0;DP4=370,393,4,4;EFF=SYNONYMOUS_CODING(LOW|SILENT|ctT/ctA|L1438|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),SYNONYMOUS_CODING(LOW|SILENT|ctT/ctA|L1438|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),SYNONYMOUS_CODING(LOW|SILENT|ctT/ctA|L620|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ctT/ctA|L620|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 4891 . C T 1382.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1943;AF=0.037571;SB=2;DP4=911,940,42,38;EFF=SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T1542|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T1542|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T724|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T724|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5239 . C T 92.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1340;AF=0.00597;SB=0;DP4=632,695,4,4;EFF=SYNONYMOUS_CODING(LOW|SILENT|taC/taT|Y1658|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|taC/taT|Y1658|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|taC/taT|Y840|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|taC/taT|Y840|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5386 . T G 49314.0 PASS DP=1745;AF=0.866476;SB=5;DP4=2,6,861,870;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5743 . G C 551.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2274;AF=0.01715;SB=1;DP4=1115,1091,30,27;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5744 . T C 676.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2270;AF=0.020264;SB=2;DP4=1110,1098,33,27;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5817 . C T 138.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1923;AF=0.00624;SB=10;DP4=948,943,16,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A1851V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A1851V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A1033V|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A1033V|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5818 . TTTAC T 174.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1882;AF=0.005313;SB=0;DP4=954,945,5,5;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||cttaca/|LT1853|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||cttaca/|LT1853|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||cttaca/|LT1035|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||cttaca/|LT1035|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 6508 . T G 81.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=387;AF=0.01292;SB=0;DP4=202,177,3,3;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaG|N2081K|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaG|N2081K|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaG|N1263K|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaG|N1263K|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6512 . AGTT A 13635.0 PASS DP=386;AF=0.997409;SB=6;DP4=0,2,206,179;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6653 . GTTAATAGTGTCCCTTGGGATACTATAGCTA G 248.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=672;AF=0.016369;SB=0;DP4=329,332,5,6;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaatagtgtcccttgggatactatagctaat/gat|VNSVPWDTIAN2130D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaatagtgtcccttgggatactatagctaat/gat|VNSVPWDTIAN2130D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaatagtgtcccttgggatactatagctaat/gat|VNSVPWDTIAN1312D|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaatagtgtcccttgggatactatagctaat/gat|VNSVPWDTIAN1312D|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6654 . TTAATAGTGTCCCTTGGGATACTATAGC T 146.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=672;AF=0.010417;SB=1;DP4=330,335,4,3;INDEL;HRUN=2;EFF=CODON_DELETION(MODERATE||agtgtcccttgggatactatagctaat/|SVPWDTIAN2132|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||agtgtcccttgggatactatagctaat/|SVPWDTIAN2132|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||agtgtcccttgggatactatagctaat/|SVPWDTIAN1314|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||agtgtcccttgggatactatagctaat/|SVPWDTIAN1314|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 6696 . C CT 138.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=542;AF=0.012915;SB=0;DP4=275,274,4,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ctt/Tctt|L2146S?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L2146S?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L1328S?|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L1328S?|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 6787 . T C 87.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=610;AF=0.009836;SB=0;DP4=311,292,3,3;EFF=SYNONYMOUS_CODING(LOW|SILENT|acT/acC|T2174|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|acT/acC|T2174|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|acT/acC|T1356|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|acT/acC|T1356|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6811 . TACTA T 94.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=707;AF=0.007072;SB=1;DP4=349,353,3,2;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||actaga/|TR2183|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),FRAME_SHIFT(HIGH||actaga/|TR2183|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),FRAME_SHIFT(HIGH||actaga/|TR1365|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),FRAME_SHIFT(HIGH||actaga/|TR1365|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 7175 . TTA T 114.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=637;AF=0.009419;SB=0;DP4=336,297,3,3;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||tta/|L2304|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),FRAME_SHIFT(HIGH||tta/|L2304|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),FRAME_SHIFT(HIGH||tta/|L1486|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),FRAME_SHIFT(HIGH||tta/|L1486|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 7615 . GAATTGTGTT G 134.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1869;AF=0.00428;SB=0;DP4=918,943,4,4;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaattgtgat/gat|VNCD2453D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaattgtgat/gat|VNCD2453D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaattgtgat/gat|VNCD1635D|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaattgtgat/gat|VNCD1635D|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 7617 . ATTGTG A 260.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1862;AF=0.007519;SB=0;DP4=915,940,7,7;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||tgtgtt/|CV2452|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgtgtt/|CV2452|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgtgtt/|CV1634|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgtgtt/|CV1634|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 7622 . GTTAA G 196.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1884;AF=0.005839;SB=0;DP4=925,949,5,6;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||aattgt/|NC2454|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aattgt/|NC2454|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aattgt/|NC1636|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aattgt/|NC1636|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 7625 . AATT A 178.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1854;AF=0.005933;SB=0;DP4=910,934,5,6;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattgt/agt|NC2454S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattgt/agt|NC2454S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattgt/agt|NC1636S|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattgt/agt|NC1636S|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 8361 . T G 92.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1004;AF=0.006972;SB=1;DP4=554,439,3,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTt/aGt|I2699S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTt/aGt|I2699S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTt/aGt|I1881S|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTt/aGt|I1881S|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 8376 . CA C 142.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=961;AF=0.008325;SB=0;DP4=529,424,4,4;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||agt/|S2706|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||agt/|S2706|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||agt/|S1888|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||agt/|S1888|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 8393 . G A 39024.0 PASS DP=1122;AF=0.926916;SB=0;DP4=3,3,622,489;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 8585 . AT A 163.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1386;AF=0.006494;SB=0;DP4=651,726,4,5;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||att/|I2774|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||att/|I2774|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||att/|I11|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||att/|I11|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 8606 . CT C 148.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1239;AF=0.007264;SB=0;DP4=563,667,4,5;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||ttt/|F2782|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F2782|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F19|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F19|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 9541 . CTGTTTAACACCAGTTTACTCATTCTTACCTGG C 79.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1686;AF=0.002966;SB=0;DP4=910,771,3,2;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||acaccagtttactcattcttacctggtgtttat/|TPVYSFLPGVY3095|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acaccagtttactcattcttacctggtgtttat/|TPVYSFLPGVY3095|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acaccagtttactcattcttacctggtgtttat/|TPVYSFLPGVY332|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acaccagtttactcattcttacctggtgtttat/|TPVYSFLPGVY332|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 9996 . C T 240.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1656;AF=0.010266;SB=3;DP4=810,824,13,9;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCa/tTa|S3244L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCa/tTa|S3244L|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCa/tTa|S481L|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCa/tTa|S481L|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10029 . C T 49314.0 PASS DP=1563;AF=0.864363;SB=9;DP4=4,0,774,771;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10323 . A G 85.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1985;AF=0.00403;SB=0;DP4=969,998,4,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K3353R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K3353R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K90R|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K90R|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10352 . AAGTATAAGTTTGTTCGCATTCAACCAGGACAGACTTTTT A 76.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1871;AF=0.002672;SB=0;DP4=893,990,2,3;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aagtataagtttgttcgcattcaaccaggacagactttttca/aca|KYKFVRIQPGQTFS3363T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aagtataagtttgttcgcattcaaccaggacagactttttca/aca|KYKFVRIQPGQTFS3363T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aagtataagtttgttcgcattcaaccaggacagactttttca/aca|KYKFVRIQPGQTFS100T|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aagtataagtttgttcgcattcaaccaggacagactttttca/aca|KYKFVRIQPGQTFS100T|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10408 . C T 99.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1385;AF=0.005776;SB=5;DP4=626,745,8,5;EFF=SYNONYMOUS_CODING(LOW|SILENT|taC/taT|Y3381|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|taC/taT|Y3381|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|taC/taT|Y118|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|taC/taT|Y118|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10449 . C A 46894.0 PASS DP=1422;AF=0.888186;SB=11;DP4=0,5,666,739;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10484 . T G 658.0 PASS DP=742;AF=0.044474;SB=5;DP4=366,334,18,24;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10541 . C A 492.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=929;AF=0.03014;SB=1;DP4=454,439,15,17;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10698 . GA G 87.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=775;AF=0.006452;SB=0;DP4=371,409,2,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||gga/|G3478|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),FRAME_SHIFT(HIGH||gga/|G3478|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),FRAME_SHIFT(HIGH||gga/|G215|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),FRAME_SHIFT(HIGH||gga/|G215|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 10769 . TATG T 124.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1282;AF=0.00546;SB=0;DP4=646,629,4,3;INDEL;HRUN=1;EFF=STOP_GAINED+CODON_CHANGE_PLUS_CODON_DELETION(HIGH||tatgaa/taa|YE3502*|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),STOP_GAINED+CODON_CHANGE_PLUS_CODON_DELETION(HIGH||tatgaa/taa|YE3502*|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),STOP_GAINED+CODON_CHANGE_PLUS_CODON_DELETION(HIGH||tatgaa/taa|YE239*|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),STOP_GAINED+CODON_CHANGE_PLUS_CODON_DELETION(HIGH||tatgaa/taa|YE239*|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.04);NMD=(ORF1ab|GU280_gp01|28|0.04) +NC_045512.2 10935 . TTGATGTTGTTA T 59.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1527;AF=0.00262;SB=0;DP4=761,764,2,2;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tttgatgttgttaga/|FDVVR3557|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),FRAME_SHIFT(HIGH||tttgatgttgttaga/|FDVVR3557|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),FRAME_SHIFT(HIGH||tttgatgttgttaga/|FDVVR294|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),FRAME_SHIFT(HIGH||tttgatgttgttaga/|FDVVR294|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 10977 . C T 99.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1287;AF=0.006216;SB=5;DP4=620,648,9,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCa/gTa|A3571V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCa/gTa|A3571V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCa/gTa|A2V|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCa/gTa|A2V|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11039 . T C 87.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1303;AF=0.00614;SB=0;DP4=629,661,5,5;EFF=SYNONYMOUS_CODING(LOW|SILENT|Tta/Cta|L3592|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|Tta/Cta|L3592|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|Tta/Cta|L23|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|Tta/Cta|L23|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11178 . T G 122.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1657;AF=0.006035;SB=0;DP4=808,837,6,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTg/tGg|L3638W|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTg/tGg|L3638W|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTg/tGg|L69W|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTg/tGg|L69W|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11266 . GGATATGGTTGATACTAGTTTGTCTGGTT G 77.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1595;AF=0.003135;SB=0;DP4=766,832,2,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||gatatggttgatactagtttgtctggtttt/|DMVDTSLSGF3668|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),FRAME_SHIFT(HIGH||gatatggttgatactagtttgtctggtttt/|DMVDTSLSGF3668|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),FRAME_SHIFT(HIGH||gatatggttgatactagtttgtctggtttt/|DMVDTSLSGF99|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),FRAME_SHIFT(HIGH||gatatggttgatactagtttgtctggtttt/|DMVDTSLSGF99|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11282 . AGTTTGTCTG A 47790.0 PASS DP=1422;AF=0.901547;SB=9;DP4=68,59,591,691;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 11282 . AGTTTGTCTGGTTT A 269.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1422;AF=0.009845;SB=2;DP4=68,59,6,8;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||agtttgtctggtttt/|SLSGF3673|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),FRAME_SHIFT(HIGH||agtttgtctggtttt/|SLSGF3673|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),FRAME_SHIFT(HIGH||agtttgtctggtttt/|SLSGF104|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),FRAME_SHIFT(HIGH||agtttgtctggtttt/|SLSGF104|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11483 . GTTACTTCTAACTACTCAGGTGTAGTTACAACTGTCATGTTT G 454.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3012;AF=0.007968;SB=0;DP4=1485,1505,12,12;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||acttctaactactcaggtgtagttacaactgtcatgtttttg/|TSNYSGVVTTVMFL3741|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acttctaactactcaggtgtagttacaactgtcatgtttttg/|TSNYSGVVTTVMFL3741|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acttctaactactcaggtgtagttacaactgtcatgtttttg/|TSNYSGVVTTVMFL172|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acttctaactactcaggtgtagttacaactgtcatgtttttg/|TSNYSGVVTTVMFL172|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11486 . ACTTCTAACTACTCAGGTGTAGTTACAACTGTCATG A 117.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3002;AF=0.002665;SB=0;DP4=1491,1511,4,4;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||acttctaactactcaggtgtagttacaactgtcatg/|TSNYSGVVTTVM3741|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),FRAME_SHIFT(HIGH||acttctaactactcaggtgtagttacaactgtcatg/|TSNYSGVVTTVM3741|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),FRAME_SHIFT(HIGH||acttctaactactcaggtgtagttacaactgtcatg/|TSNYSGVVTTVM172|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),FRAME_SHIFT(HIGH||acttctaactactcaggtgtagttacaactgtcatg/|TSNYSGVVTTVM172|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11486 . ACTT A 80.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3002;AF=0.001999;SB=0;DP4=1491,1511,3,3;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||tct/|S3742|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||tct/|S3742|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||tct/|S173|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||tct/|S173|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 11534 . G A 136.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2849;AF=0.004914;SB=5;DP4=1387,1434,8,14;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G3757S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G3757S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G188S|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G188S|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11537 . A G 49314.0 PASS DP=2822;AF=0.890149;SB=0;DP4=2,2,1379,1431;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11630 . TTTTGTACTTG T 114.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1722;AF=0.004065;SB=0;DP4=784,933,3,4;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||tgtacttgttac/|CTCY3790|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgtacttgttac/|CTCY3790|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgtacttgttac/|CTCY221|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgtacttgttac/|CTCY221|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11654 . T C 132.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1654;AF=0.006651;SB=3;DP4=751,884,8,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ttt/Ctt|F3797L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ttt/Ctt|F3797L|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ttt/Ctt|F228L|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ttt/Ctt|F228L|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 12137 . G A 76.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1636;AF=0.004279;SB=0;DP4=811,805,5,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A3958T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A3958T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A16T|197|ORF1ab|protein_coding|CODING|YP_009725304.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A16T|197|ORF1ab|protein_coding|CODING|YP_009742615.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 12748 . T G 104.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1439;AF=0.006254;SB=1;DP4=712,707,7,5;EFF=SYNONYMOUS_CODING(LOW|SILENT|acT/acG|T4161|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|acT/acG|T4161|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|acT/acG|T21|112|ORF1ab|protein_coding|CODING|YP_009725305.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|acT/acG|T21|112|ORF1ab|protein_coding|CODING|YP_009742616.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 12756 . CTGA C 142.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1416;AF=0.00565;SB=0;DP4=728,728,4,4;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gatgac/gac|DD4165D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gatgac/gac|DD4165D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gatgac/gac|DD25D|112|ORF1ab|protein_coding|CODING|YP_009725305.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gatgac/gac|DD25D|112|ORF1ab|protein_coding|CODING|YP_009742616.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 12866 . G A 118.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1783;AF=0.005609;SB=2;DP4=891,879,7,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gga/Aga|G4201R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gga/Aga|G4201R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gga/Aga|G61R|112|ORF1ab|protein_coding|CODING|YP_009725305.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gga/Aga|G61R|112|ORF1ab|protein_coding|CODING|YP_009742616.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13162 . TAC T 227.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2946;AF=0.004752;SB=0;DP4=1433,1506,7,7;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||act/|T4302|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||act/|T4302|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||act/|T49|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||act/|T49|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.11) +NC_045512.2 13195 . T C 49314.0 PASS DP=3110;AF=0.914791;SB=0;DP4=2,2,1639,1462;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13339 . T A 103.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3420;AF=0.003216;SB=0;DP4=1689,1703,7,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N4358K|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N4358K|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N105K|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N105K|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13358 . C T 191.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3401;AF=0.004999;SB=0;DP4=1674,1695,12,11;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L4365F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L4365F|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L112F|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L112F|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13791 . A C 225.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=908;AF=0.01652;SB=4;DP4=480,410,7,10;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caC|Q4509H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caC|Q117H|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13820 . T C 199.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1149;AF=0.012185;SB=0;DP4=611,519,8,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cTc/cCc|L4519P|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cTc/cCc|L127P|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13962 . A G 83.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1486;AF=0.005384;SB=0;DP4=736,731,5,5;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtA/gtG|V4566|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),SYNONYMOUS_CODING(LOW|SILENT|gtA/gtG|V174|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13994 . CT C 63.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1358;AF=0.002946;SB=0;DP4=685,677,2,2;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||ttg/|L4578|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L186|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 14001 . A T 94.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1410;AF=0.005674;SB=1;DP4=702,694,5,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|ttA/ttT|L4579F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|ttA/ttT|L187F|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 14009 . T C 124.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1460;AF=0.006849;SB=9;DP4=711,720,16,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTa/gCa|V4582A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTa/gCa|V190A|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 14408 . C T 49193.0 PASS DP=1454;AF=0.917469;SB=0;DP4=4,3,738,700;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P4715L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P323L|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 14412 . AAGTT A 61.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1431;AF=0.002795;SB=0;DP4=733,694,2,2;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||agtttt/|SF4717|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),FRAME_SHIFT(HIGH||agtttt/|SF325|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 14574 . TGCTA T 298.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1570;AF=0.009554;SB=0;DP4=774,781,8,7;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||gctatg/|AM4771|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),FRAME_SHIFT(HIGH||gctatg/|AM379|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 14864 . TTG T 113.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=945;AF=0.006349;SB=0;DP4=472,471,3,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||gtt/|V4868|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gtt/|V476|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 15157 . C A 121.0 sb_fdr;min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1194;AF=0.007538;SB=471;DP4=617,435,1,141;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Aaa|Q4965K|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Aaa|Q573K|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15240 . C T 39303.0 PASS DP=1116;AF=0.932796;SB=0;DP4=0,0,530,584;EFF=SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N4992|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N600|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15266 . T C 142.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1015;AF=0.009852;SB=1;DP4=468,528,7,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTa/gCa|V5001A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTa/gCa|V609A|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15636 . T C 194.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1993;AF=0.007526;SB=0;DP4=1044,927,8,8;EFF=SYNONYMOUS_CODING(LOW|SILENT|taT/taC|Y5124|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),SYNONYMOUS_CODING(LOW|SILENT|taT/taC|Y732|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15690 . T C 210.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2551;AF=0.007056;SB=3;DP4=1216,1278,14,10;EFF=SYNONYMOUS_CODING(LOW|SILENT|cgT/cgC|R5142|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),SYNONYMOUS_CODING(LOW|SILENT|cgT/cgC|R750|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15726 . T C 324.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2702;AF=0.009993;SB=2;DP4=1322,1344,16,20;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcT/gcC|A5154|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcC|A762|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15819 . T G 83.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2384;AF=0.003775;SB=9;DP4=1125,1237,5,13;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|ttT/ttG|F5185L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|ttT/ttG|F793L|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15917 . ATG A 125.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1347;AF=0.005939;SB=0;DP4=1219,1210,4,4;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||gtgtac/|VY5219|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gtgtac/|VY827|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 16276 . T C 86.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1910;AF=0.004188;SB=0;DP4=937,959,5,5;EFF=SYNONYMOUS_CODING(LOW|SILENT|Tta/Cta|L5338|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),SYNONYMOUS_CODING(LOW|SILENT|Tta/Cta|L14|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 16907 . AT A 82.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2421;AF=0.002478;SB=0;DP4=1207,1208,3,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttt/|F5549|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F225|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 17030 . ATGT A 173.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=3145;AF=0.003498;SB=0;DP4=1535,1605,5,6;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttgca/gca|VA5590A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttgca/gca|VA266A|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 17148 . AGTGTATACAGCTTGCTCTCATGCCGCT A 67.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1148;AF=0.003484;SB=0;DP4=576,571,2,2;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gtgtatacagcttgctctcatgccgctgtt/gtt|VYTACSHAAV5629V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gtgtatacagcttgctctcatgccgctgtt/gtt|VYTACSHAAV305V|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 17408 . TA T 124.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1305;AF=0.00613;SB=0;DP4=661,638,4,4;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||tta/|L5715|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),FRAME_SHIFT(HIGH||tta/|L391|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 17539 . G A 78.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2605;AF=0.003455;SB=2;DP4=1293,1284,10,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gac/Aac|D5759N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gac/Aac|D435N|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 17580 . T C 261.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2306;AF=0.008673;SB=1;DP4=1135,1142,12,15;EFF=SYNONYMOUS_CODING(LOW|SILENT|atT/atC|I5772|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),SYNONYMOUS_CODING(LOW|SILENT|atT/atC|I448|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 17918 . T G 89.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=635;AF=0.009449;SB=1;DP4=298,330,2,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTt/tGt|F5885C|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTt/tGt|F561C|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18163 . A G 1218.0 PASS DP=41;AF=0.804878;SB=0;DP4=0,0,21,20;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I5967V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I42V|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18391 . G A 94.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=857;AF=0.008168;SB=0;DP4=427,414,4,3;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtt/Att|V6043I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtt/Att|V118I|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18474 . A AT 111.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=916;AF=0.00655;SB=0;DP4=454,456,3,3;INDEL;HRUN=3;EFF=FRAME_SHIFT+STOP_GAINED(HIGH||aaa/Taaa|K6072*?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|AT|INFO_REALIGN_3_PRIME),FRAME_SHIFT+STOP_GAINED(HIGH||aaa/Taaa|K147*?|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|AT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 18735 . AT A 97.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1640;AF=0.003659;SB=0;DP4=823,811,3,3;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||ttt/|F6158|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F233|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 18739 . GATT G 135.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1634;AF=0.004896;SB=0;DP4=820,807,4,4;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gattac/gac|DY6159D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gattac/gac|DY234D|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 18788 . C T 137.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1678;AF=0.006555;SB=0;DP4=829,834,6,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aTa|T6175I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aTa|T250I|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18965 . G T 140.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1846;AF=0.006501;SB=12;DP4=954,868,17,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tGt/tTt|C6234F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tGt/tTt|C309F|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 19053 . T C 116.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2503;AF=0.004395;SB=3;DP4=1244,1234,6,9;EFF=SYNONYMOUS_CODING(LOW|SILENT|atT/atC|I6263|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),SYNONYMOUS_CODING(LOW|SILENT|atT/atC|I338|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 19239 . AT A 147.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1249;AF=0.006405;SB=1;DP4=589,691,3,5;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||ttt/|F6326|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F401|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 19517 . TGTA T 75.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=669;AF=0.005979;SB=0;DP4=358,313,2,2;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtat/ttt|LY6418F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtat/ttt|LY493F|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 19567 . G GT 72.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=798;AF=0.005013;SB=0;DP4=425,369,2,2;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||tac/tTac|Y6436L?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|GT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tac/tTac|Y511L?|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|GT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.04) +NC_045512.2 19983 . C T 170.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1638;AF=0.008547;SB=6;DP4=813,783,8,14;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtC/gtT|V6573|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|gtC/gtT|V121|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 20091 . C CA 67.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1108;AF=0.00361;SB=0;DP4=560,550,2,2;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||caa/Acaa|Q6611T?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|CA|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||caa/Acaa|Q159T?|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|CA|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 20102 . GTC G 150.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1019;AF=0.007851;SB=2;DP4=503,511,5,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||ctt/|L6614|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/|L162|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 20308 . T C 169.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1635;AF=0.007951;SB=0;DP4=801,814,7,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tat/Cat|Y6682H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tat/Cat|Y230H|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 20313 . C T 175.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1679;AF=0.008338;SB=3;DP4=810,835,10,7;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcC/gcT|A6683|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|gcC/gcT|A231|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 20701 . T C 90.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1044;AF=0.006705;SB=1;DP4=513,520,3,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y6813H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y15H|297|ORF1ab|protein_coding|CODING|YP_009725311.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 21740 . TCCAATGTTACTTGGTTCCATGCTATACATGTCTCTGGGA T 741.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1514;AF=0.021136;SB=2;DP4=739,744,14,18;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttacttggttccatgctatacatgtctctgggaccaatggt/ggt|VTWFHAIHVSGTNG62G|1273|S|protein_coding|CODING|GU280_gp02|1|T|INFO_REALIGN_3_PRIME) +NC_045512.2 21762 . C T 39876.0 PASS DP=1279;AF=0.892103;SB=12;DP4=4,0,600,634;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A67V|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21764 . ATACATG A 40467.0 PASS DP=1221;AF=0.964783;SB=0;DP4=21,24,576,602;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||atacatgtc/atc|IHV68I|1273|S|protein_coding|CODING|GU280_gp02|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 21846 . C T 43411.0 PASS DP=1194;AF=0.956449;SB=0;DP4=0,1,568,624;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T95I|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21890 . TTA T 77.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=984;AF=0.005081;SB=0;DP4=459,530,2,3;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||tta/|L110|1273|S|protein_coding|CODING|GU280_gp02|1|T);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 21985 . GGGTGTTTAT G 109.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=706;AF=0.011331;SB=0;DP4=360,338,4,4;INDEL;HRUN=3;EFF=CODON_DELETION(MODERATE||ggtgtttat/|GVY142|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 21986 . GGTGTTTATT G 22042.0 PASS DP=693;AF=0.982684;SB=1;DP4=14,11,350,331;INDEL;HRUN=3;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtgtttattac/gac|GVYY142D|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 22157 . GGTT G 70.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=866;AF=0.004619;SB=0;DP4=428,436,2,2;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggttat/gat|GY199D|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 22163 . TTTA T 71.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=842;AF=0.004751;SB=0;DP4=410,429,2,2;INDEL;HRUN=4;EFF=STOP_GAINED+CODON_CHANGE_PLUS_CODON_DELETION(HIGH||tttaaa/taa|FK201*|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22193 . AATT A 15712.0 PASS DP=537;AF=0.927374;SB=14;DP4=92,148,233,265;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattta/ata|NL211I|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22204 . T TGAGCCAGAA 11832.0 PASS DP=464;AF=0.778017;SB=0;DP4=40,49,162,199;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGAAGAt|D215EPED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22204 . T TGAGCCAGTA 68.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=464;AF=0.008621;SB=13;DP4=40,49,4,0;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGTAGAt|D215EPVD|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGTA|INFO_REALIGN_3_PRIME) +NC_045512.2 22527 . C CT 83.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1007;AF=0.004965;SB=0;DP4=521,485,3,2;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||cca/ccTa|P322P?|1273|S|protein_coding|CODING|GU280_gp02|1|CT);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 22578 . G A 36552.0 PASS DP=1018;AF=0.956778;SB=0;DP4=1,0,515,502;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGt/gAt|G339D|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22673 . T C 16406.0 PASS DP=508;AF=0.866142;SB=20;DP4=7,1,202,296;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tcc/Ccc|S371P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22674 . C T 16092.0 PASS DP=507;AF=0.859961;SB=0;DP4=1,2,206,294;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S371F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22679 . T C 17282.0 PASS DP=538;AF=0.862454;SB=10;DP4=5,1,218,311;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Cca|S373P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22686 . C T 18527.0 PASS DP=540;AF=0.911111;SB=2;DP4=2,1,220,316;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S375F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22992 . G A 11096.0 PASS DP=344;AF=0.906977;SB=0;DP4=0,0,180,162;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGc/aAc|S477N|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22995 . C A 11189.0 PASS DP=345;AF=0.884058;SB=2;DP4=1,2,180,162;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T478K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23013 . A C 16818.0 PASS DP=484;AF=0.917355;SB=5;DP4=3,0,256,224;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gCa|E484A|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23040 . A G 19461.0 PASS DP=580;AF=0.9;SB=3;DP4=0,1,298,278;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q493R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23048 . G A 24975.0 PASS DP=688;AF=0.953488;SB=0;DP4=0,0,358,330;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G496S|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23055 . A G 22450.0 PASS DP=711;AF=0.857947;SB=0;DP4=0,0,367,342;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q498R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23063 . A T 30725.0 PASS DP=852;AF=0.965962;SB=0;DP4=0,0,446,406;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aat/Tat|N501Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23075 . T C 27264.0 PASS DP=854;AF=0.877049;SB=17;DP4=7,0,439,404;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y505H|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23202 . C A 44060.0 PASS DP=1267;AF=0.923441;SB=3;DP4=1,0,623,639;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T547K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23267 . A G 87.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1634;AF=0.004896;SB=0;DP4=816,807,5,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I569V|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23403 . A G 49314.0 PASS DP=2451;AF=0.871889;SB=33;DP4=11,0,1208,1223;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D614G|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23517 . G A 119.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2138;AF=0.005145;SB=0;DP4=984,1104,6,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGg/gAg|G652E|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23525 . C T 49314.0 PASS DP=2152;AF=0.930762;SB=0;DP4=0,0,1022,1125;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cat/Tat|H655Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23568 . GTA G 62.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1434;AF=0.002789;SB=0;DP4=667,769,2,2;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||atatgc/|IC670|1273|S|protein_coding|CODING|GU280_gp02|1|G|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 23599 . T G 31844.0 PASS DP=946;AF=0.914376;SB=0;DP4=0,0,425,520;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaG|N679K|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23604 . C A 27971.0 PASS DP=805;AF=0.934161;SB=2;DP4=0,2,361,440;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cAt|P681H|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23948 . G T 21096.0 PASS DP=619;AF=0.898223;SB=0;DP4=1,0,326,285;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gat/Tat|D796Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24130 . C A 19310.0 PASS DP=581;AF=0.886403;SB=2;DP4=0,2,258,318;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaC/aaA|N856K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24358 . C A 81.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1436;AF=0.004875;SB=15;DP4=721,695,4,13;EFF=SYNONYMOUS_CODING(LOW|SILENT|ggC/ggA|G932|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24424 . A T 49314.0 PASS DP=1483;AF=0.942684;SB=0;DP4=0,0,738,742;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caT|Q954H|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24435 . C CT 65.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1231;AF=0.003249;SB=0;DP4=602,640,2,2;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||tta/ttTa|L959F?|1273|S|protein_coding|CODING|GU280_gp02|1|CT|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 24442 . C T 95.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1181;AF=0.006774;SB=1;DP4=555,608,4,6;EFF=SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N960|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24469 . T A 49314.0 PASS DP=2035;AF=0.932678;SB=3;DP4=5,2,1013,1013;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N969K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24503 . C T 49314.0 PASS DP=2064;AF=0.935078;SB=0;DP4=2,2,995,1055;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L981F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24594 . A AC 96.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1513;AF=0.003966;SB=0;DP4=755,752,3,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||caa/caCa|Q1011H?|1273|S|protein_coding|CODING|GU280_gp02|1|AC);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 24842 . G A 90.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=850;AF=0.008235;SB=0;DP4=443,398,4,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtc/Atc|V1094I|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24858 . G A 101.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=930;AF=0.008602;SB=11;DP4=479,434,4,11;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGc/gAc|G1099D|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 25000 . C T 21478.0 PASS DP=674;AF=0.881306;SB=9;DP4=0,4,334,330;EFF=SYNONYMOUS_CODING(LOW|SILENT|gaC/gaT|D1146|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25531 . ATTG A 66.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1201;AF=0.003331;SB=0;DP4=594,603,2,2;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttggc/ggc|VG48G|275|ORF3a|protein_coding|CODING|GU280_gp03|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 25533 . TG T 65.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1203;AF=0.003325;SB=0;DP4=595,604,2,2;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||gtt/|V48|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T);LOF=(ORF3a|GU280_gp03|1|1.00) +NC_045512.2 25584 . C T 39037.0 PASS DP=1141;AF=0.912358;SB=0;DP4=0,1,562,575;EFF=SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T64|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 25650 . GTT G 134.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=924;AF=0.007576;SB=0;DP4=449,501,3,4;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||ttt/|F87|275|ORF3a|protein_coding|CODING|GU280_gp03|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF3a|GU280_gp03|1|1.00) +NC_045512.2 25797 . C CA 110.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1398;AF=0.005007;SB=1;DP4=698,693,3,4;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aac/aaAc|N137K?|275|ORF3a|protein_coding|CODING|GU280_gp03|1|CA|INFO_REALIGN_3_PRIME);LOF=(ORF3a|GU280_gp03|1|1.00) +NC_045512.2 26070 . A T 82.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2257;AF=0.003545;SB=28;DP4=1236,979,28,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaA/gaT|E226D|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 26155 . GTTGTTAATCCAGTAATGGAACCAA G 83.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2865;AF=0.002094;SB=0;DP4=1438,1453,3,3;INDEL;HRUN=2;EFF=CODON_DELETION(MODERATE||gttaatccagtaatggaaccaatt/|VNPVMEPI256|275|ORF3a|protein_coding|CODING|GU280_gp03|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 26270 . C T 49314.0 PASS DP=2570;AF=0.922179;SB=3;DP4=1,0,1205,1359;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aTa|T9I|75|E|protein_coding|CODING|GU280_gp04|1|T) +NC_045512.2 26281 . ATAGT A 85.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=2571;AF=0.002334;SB=1;DP4=1217,1369,2,4;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||gttaat/|VN14|75|E|protein_coding|CODING|GU280_gp04|1|A|INFO_REALIGN_3_PRIME);LOF=(E|GU280_gp04|1|1.00) +NC_045512.2 26467 . G C 76.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=216;AF=0.027778;SB=0;DP4=105,101,3,3;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtc/Ctc|V75L|75|E|protein_coding|CODING|GU280_gp04|1|C) +NC_045512.2 26486 . TATA T 68.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=406;AF=0.019704;SB=0;DP4=200,198,4,4;INDEL;HRUN=1 +NC_045512.2 26490 . T TC 67.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=406;AF=0.019704;SB=0;DP4=200,198,4,4;INDEL;HRUN=2 +NC_045512.2 26530 . A G 13253.0 PASS DP=394;AF=0.916244;SB=0;DP4=0,0,194,197;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D3G|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26577 . C G 4011.0 PASS DP=136;AF=0.838235;SB=0;DP4=6,6,62,61;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Gaa|Q19E|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26709 . G A 13373.0 PASS DP=427;AF=0.847775;SB=0;DP4=2,2,197,224;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A63T|222|M|protein_coding|CODING|GU280_gp05|1|A) +NC_045512.2 26774 . GGCTTGTCTTGTAGGCTTGATGTGGCTCAGCTACTTCATTGCTTCTTTCAGACTGTT G 235.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=468;AF=0.021368;SB=1;DP4=222,243,4,6;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||gcttgtcttgtaggcttgatgtggctcagctacttcattgcttctttcagactgttt/|ACLVGLMWLSYFIASFRLF85|222|M|protein_coding|CODING|GU280_gp05|1|G);LOF=(M|GU280_gp05|1|1.00) +NC_045512.2 26778 . TGTCTTGTA T 283.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=468;AF=0.025641;SB=1;DP4=218,240,5,7;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||tgtcttgtaggc/|CLVG86|222|M|protein_coding|CODING|GU280_gp05|1|T|INFO_REALIGN_3_PRIME);LOF=(M|GU280_gp05|1|1.00) +NC_045512.2 27259 . A C 38032.0 PASS DP=1159;AF=0.88956;SB=0;DP4=2,1,612,537;EFF=SYNONYMOUS_CODING(LOW|SILENT|Agg/Cgg|R20|61|ORF6|protein_coding|CODING|GU280_gp06|1|C) +NC_045512.2 27481 . C T 98.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1960;AF=0.004592;SB=2;DP4=953,991,4,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L30F|121|ORF7a|protein_coding|CODING|GU280_gp07|1|T) +NC_045512.2 27807 . C T 49314.0 PASS DP=1697;AF=0.925162;SB=6;DP4=4,1,830,853;EFF=SYNONYMOUS_CODING(LOW|SILENT|Cta/Tta|L18|43|ORF7b|protein_coding|CODING|GU280_gp08|1|T) +NC_045512.2 28214 . C CT 91.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1382;AF=0.004342;SB=0;DP4=685,702,3,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||tta/ttTa|L109F?|121|ORF8|protein_coding|CODING|GU280_gp09|1|CT|INFO_REALIGN_3_PRIME);LOF=(ORF8|GU280_gp09|1|1.00) +NC_045512.2 28271 . A T 49314.0 PASS DP=2424;AF=0.909653;SB=4;DP4=1,3,1205,1198 +NC_045512.2 28311 . C T 49314.0 PASS DP=2555;AF=0.789041;SB=26;DP4=8,28,1187,1286;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cTc|P13L|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28361 . GGAGAACGCA G 49314.0 PASS DP=2305;AF=0.802169;SB=2;DP4=229,238,876,973;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggagaacgcagt/ggt|GERS30G|419|N|protein_coding|CODING|GU280_gp10|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 28363 . AGAACGCAGT A 486.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1910;AF=0.017801;SB=57;DP4=900,990,30,4;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gaacgcagtggg/ggg|ERSG31G|419|N|protein_coding|CODING|GU280_gp10|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 28881 . G A 33203.0 PASS DP=948;AF=0.925106;SB=6;DP4=0,2,490,453;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGg/aAg|R203K|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28882 . G A 31137.0 PASS DP=946;AF=0.884778;SB=19;DP4=0,6,487,440;EFF=SYNONYMOUS_CODING(LOW|SILENT|agG/agA|R203|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28883 . G C 32607.0 PASS DP=948;AF=0.920886;SB=6;DP4=3,0,486,458;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gga/Cga|G204R|419|N|protein_coding|CODING|GU280_gp10|1|C) +NC_045512.2 28987 . CCAA C 88.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=951;AF=0.005258;SB=0;DP4=483,488,2,3;INDEL;HRUN=2;EFF=CODON_DELETION(MODERATE||caa/|Q242|419|N|protein_coding|CODING|GU280_gp10|1|C|INFO_REALIGN_3_PRIME) +NC_045512.2 29081 . GTA G 140.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1105;AF=0.00724;SB=0;DP4=546,557,4,4;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||gta/|V270|419|N|protein_coding|CODING|GU280_gp10|1|G);LOF=(N|GU280_gp10|1|1.00) +NC_045512.2 29313 . AAGATCAAGTCATTTTGCTGAATAAGCAT A 105.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1312;AF=0.004573;SB=0;DP4=659,647,3,3;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||gatcaagtcattttgctgaataagcatatt/|DQVILLNKHI348|419|N|protein_coding|CODING|GU280_gp10|1|A|INFO_REALIGN_3_PRIME);LOF=(N|GU280_gp10|1|1.00) +NC_045512.2 29363 . CCA C 75.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1422;AF=0.003516;SB=0;DP4=710,711,3,2;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||ccacca/|PP364|419|N|protein_coding|CODING|GU280_gp10|1|C|INFO_REALIGN_3_PRIME);LOF=(N|GU280_gp10|1|1.00) +NC_045512.2 29386 . C CA 91.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1414;AF=0.004243;SB=0;DP4=701,707,3,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aag/aaAg|K373K?|419|N|protein_coding|CODING|GU280_gp10|1|CA|INFO_REALIGN_3_PRIME);LOF=(N|GU280_gp10|1|1.00) +NC_045512.2 29426 . A G 77.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1350;AF=0.005185;SB=0;DP4=647,694,4,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aga/Gga|R385G|419|N|protein_coding|CODING|GU280_gp10|1|G) +NC_045512.2 29580 . CT C 97.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1147;AF=0.005231;SB=0;DP4=591,556,3,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttt/|F9|38|ORF10|protein_coding|CODING|GU280_gp11|1|C|INFO_REALIGN_3_PRIME);LOF=(ORF10|GU280_gp11|1|1.00) +NC_045512.2 29660 . T C 200.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1373;AF=0.010197;SB=0;DP4=674,675,8,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ttt/Ctt|F35L|38|ORF10|protein_coding|CODING|GU280_gp11|1|C) +NC_045512.2 29687 . AGT A 170.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1282;AF=0.00702;SB=1;DP4=633,640,5,4;INDEL;HRUN=1 diff --git a/example_data/example_mave_data/input/sample-03.vcf b/example_data/example_mave_data/input/sample-03.vcf new file mode 100644 index 0000000..e22e7a3 --- /dev/null +++ b/example_data/example_mave_data/input/sample-03.vcf @@ -0,0 +1,104 @@ +##fileformat=VCFv4.0 +##FILTER= +##fileDate=20240114 +##source=lofreq call --verbose --ref reference.fa --call-indels --min-cov 5 --max-depth 1000000 --min-bq 30 --min-alt-bq 30 --min-mq 20 --max-mq 255 --min-jq 0 --min-alt-jq 0 --def-alt-jq 0 --sig 0.0005 --bonf dynamic --no-default-filter --no-default-filter -r NC_045512.2:1-7475 -o /data/jwd02f/main/066/348/66348158/tmp/lofreq2_call_parallelkeh4cirr/0.vcf.gz reads.bam +##reference=reference.fa +##INFO= +##INFO= --min-bq among all bases at the site"> +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##INFO= +##bcftools_annotateVersion=1.10.2+htslib-1.10.2 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites -AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 20:35:21 2024 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites +AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 20:37:46 2024 +##SnpEffVersion="4.5covid19 (build 2020-04-15 22:26), by Pablo Cingolani" +##SnpEffCmd="SnpEff -i vcf -o vcf -formatEff -classic -no-downstream -no-intergenic -no-upstream -stats /data/jwd02f/main/066/348/66348338/outputs/dataset_687078c0-9a25-45d8-b608-a582f8693ca1.dat NC_045512.2 /data/dnb09/galaxy_db/files/1/3/d/dataset_13d6e913-16ea-459c-b77a-0afba97eb90d.dat " +##INFO= +##INFO= +##INFO= +##FILTER= 0.001000"> +##SnpSiftVersion="SnpSift 4.3t (build 2017-11-24 10:18), by Pablo Cingolani" +##SnpSiftCmd="SnpSift Filter -f /data/dnb09/galaxy_db/files/e/3/6/dataset_e367213d-070e-4996-9a4c-922cf05d2e13.dat -e /data/jwd02f/main/066/348/66348993/configs/tmpve0cc43r" +##FILTER== 1"> +##SnpSiftCmd="SnpSift Filter -f /data/dnb09/galaxy_db/files/7/5/b/dataset_75bcf2db-89e2-4acb-a7d1-e9f18d8e46cc.dat -e /data/jwd05e/main/066/349/66349012/configs/tmp7b1ry_v5 --addFilter min_af_0.05Xmin_dp_1Xmin_dp_alt_10" +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO +NC_045512.2 241 . C T 8995.0 PASS DP=276;AF=0.891304;SB=0;DP4=0,0,137,139 +NC_045512.2 2330 . T A 93.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=558;AF=0.014337;SB=1;DP4=251,276,6,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2832 . A G 14215.0 PASS DP=423;AF=0.910165;SB=0;DP4=0,0,196,225;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3037 . C T 9430.0 PASS DP=286;AF=0.881119;SB=0;DP4=0,0,139,142;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5386 . T G 22019.0 PASS DP=696;AF=0.856322;SB=0;DP4=0,1,342,351;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5743 . G C 160.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=678;AF=0.016224;SB=0;DP4=335,322,8,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5744 . T C 163.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=679;AF=0.0162;SB=1;DP4=331,326,12,9;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6512 . AGTT A 10281.0 PASS DP=298;AF=0.983221;SB=0;DP4=3,2,157,136;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 8393 . G A 19750.0 PASS DP=584;AF=0.910959;SB=0;DP4=2,1,320,259;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 9221 . C T 80.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=696;AF=0.008621;SB=2;DP4=327,352,3,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Tac|H2986Y|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Tac|H2986Y|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Tac|H223Y|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Tac|H223Y|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10029 . C T 16432.0 PASS DP=548;AF=0.821168;SB=0;DP4=1,1,270,267;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10449 . C A 21422.0 PASS DP=672;AF=0.86756;SB=0;DP4=0,1,322,340;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10484 . T G 136.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=422;AF=0.018957;SB=1;DP4=215,196,5,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10541 . C A 117.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=467;AF=0.017131;SB=5;DP4=228,219,5,9;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10981 . GA G 77.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=498;AF=0.008032;SB=0;DP4=242,254,2,2;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||aga/|R3574|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aga/|R3574|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aga/|R5|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aga/|R5|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 11095 . C CT 94.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=442;AF=0.011312;SB=0;DP4=229,207,3,2;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||tta/ttTa|L3612F?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/ttTa|L3612F?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/ttTa|L43F?|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/ttTa|L43F?|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11282 . AGTTTGTCTG A 21093.0 PASS DP=619;AF=0.914378;SB=9;DP4=31,23,260,306;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 11521 . GT G 136.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1094;AF=0.007313;SB=0;DP4=537,553,4,4;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||ttg/|L3754|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L3754|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L185|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L185|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11537 . A G 33750.0 PASS DP=1079;AF=0.847081;SB=0;DP4=1,1,527,543;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13123 . TG T 65.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=703;AF=0.00569;SB=0;DP4=327,373,2,2;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||gga/|G4288|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gga/|G4288|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gga/|G35|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gga/|G35|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.11) +NC_045512.2 13176 . C T 86.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=1181;AF=0.006774;SB=0;DP4=598,569,5,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T4304I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T4304I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T51I|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T51I|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13195 . T C 33340.0 PASS DP=1036;AF=0.870656;SB=0;DP4=2,1,553,471;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 14408 . C T 17952.0 PASS DP=535;AF=0.915888;SB=0;DP4=0,0,276,255;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P4715L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P323L|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15240 . C T 20172.0 PASS DP=605;AF=0.884298;SB=0;DP4=0,0,287,313;EFF=SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N4992|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N600|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18163 . A G 4885.0 PASS DP=154;AF=0.87013;SB=0;DP4=0,0,77,76;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I5967V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I42V|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 21740 . TCCAATGTTACTTGGTTCCATGCTATACATGTCTCTGGGA T 254.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=583;AF=0.018868;SB=1;DP4=289,285,5,6;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttacttggttccatgctatacatgtctctgggaccaatggt/ggt|VTWFHAIHVSGTNG62G|1273|S|protein_coding|CODING|GU280_gp02|1|T|INFO_REALIGN_3_PRIME) +NC_045512.2 21762 . C T 14122.0 PASS DP=477;AF=0.865828;SB=0;DP4=0,0,225,236;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A67V|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21764 . ATACATG A 14993.0 PASS DP=450;AF=0.975556;SB=0;DP4=5,6,217,222;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||atacatgtc/atc|IHV68I|1273|S|protein_coding|CODING|GU280_gp02|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 21846 . C T 15843.0 PASS DP=443;AF=0.948081;SB=0;DP4=0,0,210,231;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T95I|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21986 . GGTGTTTATT G 7426.0 PASS DP=243;AF=0.975309;SB=0;DP4=8,9,124,113;INDEL;HRUN=3;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtgtttattac/gac|GVYY142D|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 22193 . AATT A 7224.0 PASS DP=242;AF=0.933884;SB=10;DP4=41,65,110,116;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattta/ata|NL211I|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22204 . T TGAGCCAGAA 5487.0 PASS DP=208;AF=0.783654;SB=0;DP4=18,23,76,87;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGAAGAt|D215EPED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22204 . T TGAGCCAGTA 57.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=208;AF=0.014423;SB=0;DP4=18,23,1,2;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGTAGAt|D215EPVD|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGTA|INFO_REALIGN_3_PRIME) +NC_045512.2 22578 . G A 16559.0 PASS DP=463;AF=0.958963;SB=0;DP4=0,0,232,230;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGt/gAt|G339D|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22673 . T C 8364.0 PASS DP=261;AF=0.8659;SB=3;DP4=1,0,109,150;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tcc/Ccc|S371P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22674 . C T 8166.0 PASS DP=259;AF=0.853282;SB=0;DP4=0,1,110,148;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S371F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22679 . T C 8537.0 PASS DP=266;AF=0.864662;SB=0;DP4=0,0,113,151;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Cca|S373P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22686 . C T 9336.0 PASS DP=267;AF=0.932584;SB=3;DP4=1,0,112,153;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S375F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22992 . G A 3627.0 PASS DP=114;AF=0.885965;SB=0;DP4=0,0,64,50;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGc/aAc|S477N|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22995 . C A 3941.0 PASS DP=118;AF=0.915254;SB=0;DP4=0,0,65,53;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T478K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23013 . A C 6286.0 PASS DP=192;AF=0.875;SB=0;DP4=0,0,101,91;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gCa|E484A|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23040 . A G 6861.0 PASS DP=220;AF=0.836364;SB=0;DP4=1,0,110,107;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q493R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23048 . G A 9362.0 PASS DP=265;AF=0.932076;SB=3;DP4=0,1,138,125;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G496S|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23055 . A G 8423.0 PASS DP=273;AF=0.838828;SB=3;DP4=0,1,140,130;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q498R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23063 . A T 12198.0 PASS DP=343;AF=0.956268;SB=0;DP4=0,0,180,163;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aat/Tat|N501Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23075 . T C 10787.0 PASS DP=350;AF=0.842857;SB=5;DP4=6,2,175,166;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y505H|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23202 . C A 15853.0 PASS DP=463;AF=0.909287;SB=0;DP4=0,1,229,233;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T547K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23403 . A G 29700.0 PASS DP=968;AF=0.845041;SB=9;DP4=5,1,474,484;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D614G|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23525 . C T 26555.0 PASS DP=801;AF=0.88764;SB=9;DP4=3,0,375,422;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cat/Tat|H655Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23599 . T G 12933.0 PASS DP=411;AF=0.86618;SB=0;DP4=0,0,185,224;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaG|N679K|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23604 . C A 10807.0 PASS DP=323;AF=0.910217;SB=0;DP4=0,1,142,176;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cAt|P681H|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23948 . G T 11677.0 PASS DP=344;AF=0.898256;SB=0;DP4=0,0,183,159;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gat/Tat|D796Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24130 . C A 11934.0 PASS DP=372;AF=0.854839;SB=0;DP4=3,3,168,198;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaC/aaA|N856K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24424 . A T 17998.0 PASS DP=532;AF=0.919173;SB=9;DP4=0,3,268,260;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caT|Q954H|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24469 . T A 26784.0 PASS DP=788;AF=0.911168;SB=0;DP4=3,2,395,388;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N969K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24503 . C T 27126.0 PASS DP=812;AF=0.907635;SB=3;DP4=1,0,395,411;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L981F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25000 . C T 10192.0 PASS DP=322;AF=0.86646;SB=4;DP4=1,3,163,155;EFF=SYNONYMOUS_CODING(LOW|SILENT|gaC/gaT|D1146|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25584 . C T 17520.0 PASS DP=533;AF=0.891182;SB=0;DP4=0,0,259,270;EFF=SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T64|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 26270 . C T 20403.0 PASS DP=613;AF=0.882545;SB=3;DP4=1,0,274,333;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aTa|T9I|75|E|protein_coding|CODING|GU280_gp04|1|T) +NC_045512.2 26530 . A G 3757.0 PASS DP=120;AF=0.85;SB=0;DP4=0,0,56,62;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D3G|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26577 . C G 1350.0 PASS DP=48;AF=0.791667;SB=0;DP4=1,1,23,23;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Gaa|Q19E|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26709 . G A 2362.0 PASS DP=85;AF=0.764706;SB=0;DP4=1,1,38,41;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A63T|222|M|protein_coding|CODING|GU280_gp05|1|A) +NC_045512.2 27259 . A C 13820.0 PASS DP=417;AF=0.894484;SB=0;DP4=0,0,225,191;EFF=SYNONYMOUS_CODING(LOW|SILENT|Agg/Cgg|R20|61|ORF6|protein_coding|CODING|GU280_gp06|1|C) +NC_045512.2 27807 . C T 18288.0 PASS DP=532;AF=0.930451;SB=0;DP4=0,0,258,274;EFF=SYNONYMOUS_CODING(LOW|SILENT|Cta/Tta|L18|43|ORF7b|protein_coding|CODING|GU280_gp08|1|T) +NC_045512.2 28271 . A T 27779.0 PASS DP=817;AF=0.908201;SB=9;DP4=3,0,394,416 +NC_045512.2 28311 . C T 23847.0 PASS DP=817;AF=0.809058;SB=2;DP4=1,3,382,417;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cTc|P13L|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28361 . GGAGAACGCA G 17394.0 PASS DP=661;AF=0.803328;SB=0;DP4=61,69,247,284;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggagaacgcagt/ggt|GERS30G|419|N|protein_coding|CODING|GU280_gp10|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 28363 . AGAACGCAGT A 120.0 min_af_0.05Xmin_dp_1Xmin_dp_alt_10 DP=548;AF=0.014599;SB=15;DP4=253,288,7,1;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gaacgcagtggg/ggg|ERSG31G|419|N|protein_coding|CODING|GU280_gp10|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 28881 . G A 11288.0 PASS DP=327;AF=0.917431;SB=0;DP4=0,0,170,157;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGg/aAg|R203K|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28882 . G A 10527.0 PASS DP=327;AF=0.87156;SB=3;DP4=0,1,170,149;EFF=SYNONYMOUS_CODING(LOW|SILENT|agG/agA|R203|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28883 . G C 11180.0 PASS DP=327;AF=0.920489;SB=0;DP4=0,0,170,157;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gga/Cga|G204R|419|N|protein_coding|CODING|GU280_gp10|1|C) diff --git a/example_data/example_mave_data/input/sample-04.vcf b/example_data/example_mave_data/input/sample-04.vcf new file mode 100644 index 0000000..dd874ed --- /dev/null +++ b/example_data/example_mave_data/input/sample-04.vcf @@ -0,0 +1,125 @@ +##fileformat=VCFv4.0 +##FILTER= +##fileDate=20240114 +##source=lofreq call --verbose --ref reference.fa --call-indels --min-cov 5 --max-depth 1000000 --min-bq 30 --min-alt-bq 30 --min-mq 20 --max-mq 255 --min-jq 0 --min-alt-jq 0 --def-alt-jq 0 --sig 0.0005 --bonf dynamic --no-default-filter --no-default-filter -r NC_045512.2:1-7475 -o /data/jwd05e/main/066/348/66348159/tmp/lofreq2_call_parallelg2b1i656/0.vcf.gz reads.bam +##reference=reference.fa +##INFO= +##INFO= --min-bq among all bases at the site"> +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##INFO= +##bcftools_annotateVersion=1.10.2+htslib-1.10.2 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites -AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 20:37:07 2024 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites +AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 20:41:19 2024 +##SnpEffVersion="4.5covid19 (build 2020-04-15 22:26), by Pablo Cingolani" +##SnpEffCmd="SnpEff -i vcf -o vcf -formatEff -classic -no-downstream -no-intergenic -no-upstream -stats /data/jwd05e/main/066/348/66348339/outputs/dataset_c9bf8f2a-6a14-417e-8a98-92ed8f219848.dat NC_045512.2 /data/dnb09/galaxy_db/files/4/2/c/dataset_42c6a953-bed7-4fa9-897a-0edfc4726561.dat " +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +NC_045512.2 241 . C T 16854.0 PASS DP=506;AF=0.913043;SB=0;DP4=1,1,250,252 +NC_045512.2 443 . GT G 158.0 PASS DP=1275;AF=0.007059;SB=0;DP4=651,611,5,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttg/|L61|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 443 . GTT G 61.0 PASS DP=1275;AF=0.003137;SB=0;DP4=651,611,2,2;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttg/|L61|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 507 . ATGGTCATGTTATGGT A 159.0 PASS DP=1673;AF=0.00538;SB=0;DP4=831,834,4,5;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 509 . GGTCATGTTATGGTT G 473.0 PASS DP=1661;AF=0.013847;SB=0;DP4=811,819,12,11;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 509 . GGTCATGTTA G 136.0 PASS DP=1661;AF=0.004816;SB=0;DP4=811,819,4,4;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G) +NC_045512.2 509 . GGTCATGTT G 60.0 PASS DP=1661;AF=0.002408;SB=0;DP4=811,819,2,2;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 514 . TGTTATG T 60.0 PASS DP=1675;AF=0.002388;SB=0;DP4=832,839,2,2;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||atggtt/|MV85|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||atggtt/|MV85|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME) +NC_045512.2 515 . GTTATGGTT G 95.0 PASS DP=1669;AF=0.003595;SB=0;DP4=831,838,3,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||gttatggtt/|VMV84|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),FRAME_SHIFT(HIGH||gttatggtt/|VMV84|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||gttatggtt/|VMV84|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||gttatggtt/|VMV84|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 517 . TATG T 60.0 PASS DP=1657;AF=0.002414;SB=0;DP4=822,831,2,2;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||atg/|M85|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),CODON_DELETION(MODERATE||atg/|M85|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_DELETION(MODERATE||atg/|M85|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_DELETION(MODERATE||atg/|M85|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T) +NC_045512.2 685 . AAAGTCATTT A 64.0 PASS DP=1263;AF=0.003167;SB=0;DP4=630,657,2,2;INDEL;HRUN=3;EFF=CODON_DELETION(MODERATE||aagtcattt/|KSF141|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_DELETION(MODERATE||aagtcattt/|KSF141|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_DELETION(MODERATE||aagtcattt/|KSF141|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_DELETION(MODERATE||aagtcattt/|KSF141|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A) +NC_045512.2 2113 . C T 79.0 PASS DP=1512;AF=0.00463;SB=0;DP4=726,772,5,5;EFF=SYNONYMOUS_CODING(LOW|SILENT|atC/atT|I616|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|atC/atT|I616|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|atC/atT|I436|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|atC/atT|I436|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2330 . T A 203.0 PASS DP=909;AF=0.014301;SB=2;DP4=426,451,6,9;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2832 . A G 24107.0 PASS DP=716;AF=0.913408;SB=0;DP4=0,1,329,383;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3037 . C T 14627.0 PASS DP=425;AF=0.910588;SB=3;DP4=1,0,207,212;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3862 . T A 79.0 PASS DP=132;AF=0.030303;SB=0;DP4=64,64,2,2;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V1199|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V1199|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V381|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V381|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 4440 . GTGTGGAAACTAAAGCCATAGTTTCAACTA G 78.0 PASS DP=593;AF=0.006745;SB=0;DP4=297,296,2,2;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||gtggaaactaaagccatagtttcaactata/|VETKAIVSTI1393|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gtggaaactaaagccatagtttcaactata/|VETKAIVSTI1393|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gtggaaactaaagccatagtttcaactata/|VETKAIVSTI575|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gtggaaactaaagccatagtttcaactata/|VETKAIVSTI575|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 4794 . C A 92.0 PASS DP=1023;AF=0.006843;SB=28;DP4=500,491,5,22;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tAc|S1510Y|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tAc|S1510Y|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tAc|S692Y|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tAc|S692Y|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5386 . T G 34494.0 PASS DP=1077;AF=0.862581;SB=6;DP4=0,3,530,540;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5743 . G C 227.0 PASS DP=1059;AF=0.015109;SB=1;DP4=520,513,11,13;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5744 . T C 230.0 PASS DP=1058;AF=0.015123;SB=3;DP4=514,515,15,10;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6512 . AGTT A 20035.0 PASS DP=569;AF=0.996485;SB=3;DP4=0,1,297,270;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6653 . GTTAATAGTGTCCCTTGGGATACTATAGCTA G 71.0 PASS DP=910;AF=0.004396;SB=0;DP4=458,450,2,2;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaatagtgtcccttgggatactatagctaat/gat|VNSVPWDTIAN2130D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaatagtgtcccttgggatactatagctaat/gat|VNSVPWDTIAN2130D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaatagtgtcccttgggatactatagctaat/gat|VNSVPWDTIAN1312D|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaatagtgtcccttgggatactatagctaat/gat|VNSVPWDTIAN1312D|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6655 . TAATAGTGTCCCTTGGGATACTATAGCTA T 92.0 PASS DP=909;AF=0.005501;SB=1;DP4=457,449,2,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||aatagtgtcccttgggatactatagctaat/|NSVPWDTIAN2131|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aatagtgtcccttgggatactatagctaat/|NSVPWDTIAN2131|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aatagtgtcccttgggatactatagctaat/|NSVPWDTIAN1313|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aatagtgtcccttgggatactatagctaat/|NSVPWDTIAN1313|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 6696 . C CT 281.0 PASS DP=839;AF=0.016687;SB=0;DP4=416,415,7,7;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ctt/Tctt|L2146S?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L2146S?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L1328S?|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L1328S?|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 8393 . G A 27333.0 PASS DP=787;AF=0.928844;SB=5;DP4=3,0,436,347;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 9125 . TA T 71.0 PASS DP=857;AF=0.004667;SB=0;DP4=426,427,2,2;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||tat/|Y2954|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),FRAME_SHIFT(HIGH||tat/|Y2954|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),FRAME_SHIFT(HIGH||tat/|Y191|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),FRAME_SHIFT(HIGH||tat/|Y191|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 10029 . C T 29085.0 PASS DP=924;AF=0.856061;SB=0;DP4=3,2,456,456;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10449 . C A 33519.0 PASS DP=1046;AF=0.868069;SB=1;DP4=2,4,494,539;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10484 . T G 115.0 PASS DP=734;AF=0.010899;SB=0;DP4=384,338,6,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11282 . AGTTTGTCTG A 35550.0 PASS DP=1018;AF=0.920432;SB=11;DP4=46,35,430,507;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 11481 . CTGTTACTTCTAACTACTCAGGTGTAGTTACAACTGTCATGTTTTTGGCCAGAGGTAT C 59.0 PASS DP=1718;AF=0.002328;SB=0;DP4=857,867,2,2;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||acttctaactactcaggtgtagttacaactgtcatgtttttggccagaggtattgtt/|TSNYSGVVTTVMFLARGIV3741|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||acttctaactactcaggtgtagttacaactgtcatgtttttggccagaggtattgtt/|TSNYSGVVTTVMFLARGIV3741|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||acttctaactactcaggtgtagttacaactgtcatgtttttggccagaggtattgtt/|TSNYSGVVTTVMFLARGIV172|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||acttctaactactcaggtgtagttacaactgtcatgtttttggccagaggtattgtt/|TSNYSGVVTTVMFLARGIV172|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 11537 . A G 49314.0 PASS DP=1665;AF=0.878078;SB=0;DP4=1,1,813,840;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11636 . ACTT A 64.0 PASS DP=954;AF=0.004193;SB=0;DP4=428,526,2,2;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||acttgt/agt|TC3791S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||acttgt/agt|TC3791S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||acttgt/agt|TC222S|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||acttgt/agt|TC222S|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13195 . T C 49314.0 PASS DP=1565;AF=0.89393;SB=1;DP4=4,2,831,720;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13459 . GT G 67.0 PASS DP=1271;AF=0.003934;SB=0;DP4=572,715,2,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||tta/|L4400|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L4400|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L8|12|ORF1ab|protein_coding|CODING|YP_009725312.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L8|931|ORF1ab|protein_coding|CODING|YP_009725307.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 13461 . TTTTA T 64.0 PASS DP=1271;AF=0.003147;SB=0;DP4=563,704,2,2;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||ttttta/|FL4399|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),FRAME_SHIFT(HIGH||ttttta/|FL4399|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),FRAME_SHIFT(HIGH||ttttta/|FL7|12|ORF1ab|protein_coding|CODING|YP_009725312.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),FRAME_SHIFT(HIGH||ttttta/|FL7|931|ORF1ab|protein_coding|CODING|YP_009725307.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 14408 . C T 28174.0 PASS DP=847;AF=0.910272;SB=6;DP4=0,2,426,411;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P4715L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P323L|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15173 . C A 102.0 PASS DP=815;AF=0.008589;SB=272;DP4=423,309,0,79;EFF=STOP_GAINED(HIGH|NONSENSE|tCa/tAa|S4970*|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),STOP_GAINED(HIGH|NONSENSE|tCa/tAa|S578*|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15240 . C T 27849.0 PASS DP=797;AF=0.927227;SB=3;DP4=1,0,371,423;EFF=SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N4992|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N600|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15983 . TA T 59.0 PASS DP=1133;AF=0.00353;SB=0;DP4=588,541,2,2;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aca/|T5242|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aca/|T850|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 16935 . G T 77.0 PASS DP=1613;AF=0.00434;SB=1;DP4=799,801,6,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|atG/atT|M5557I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|atG/atT|M233I|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 17825 . C T 26141.0 PASS DP=763;AF=0.906946;SB=0;DP4=1,1,380,374;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T5854I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T530I|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18163 . A G 7301.0 PASS DP=226;AF=0.893805;SB=0;DP4=0,1,113,112;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I5967V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I42V|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 20296 . AAATT A 67.0 PASS DP=988;AF=0.004049;SB=0;DP4=492,495,2,2;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||aaatta/|KL6678|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaatta/|KL226|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 20445 . TA T 60.0 PASS DP=995;AF=0.00402;SB=0;DP4=489,500,2,2;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aac/|N6729|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aac/|N277|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 21034 . C T 26508.0 PASS DP=790;AF=0.888608;SB=0;DP4=0,0,396,384;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctc/Ttc|L6924F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctc/Ttc|L126F|297|ORF1ab|protein_coding|CODING|YP_009725311.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 21101 . G GT 155.0 PASS DP=729;AF=0.015089;SB=1;DP4=371,347,5,6;INDEL;HRUN=6;EFF=FRAME_SHIFT(HIGH||ttc/ttTc|F6948F?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|GT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttc/ttTc|F150F?|297|ORF1ab|protein_coding|CODING|YP_009725311.1|1|GT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.04) +NC_045512.2 21137 . A G 82.0 PASS DP=741;AF=0.008097;SB=0;DP4=362,366,3,3;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K6958R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K160R|297|ORF1ab|protein_coding|CODING|YP_009725311.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 21762 . C T 20845.0 PASS DP=648;AF=0.91821;SB=0;DP4=0,1,321,325;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A67V|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21764 . ATACATG A 21400.0 PASS DP=626;AF=0.995208;SB=0;DP4=1,2,312,311;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||atacatgtc/atc|IHV68I|1273|S|protein_coding|CODING|GU280_gp02|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 21846 . C T 22408.0 PASS DP=621;AF=0.951691;SB=0;DP4=0,1,299,321;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T95I|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21986 . GGTGTTTATT G 13943.0 PASS DP=439;AF=0.986333;SB=0;DP4=11,12,222,211;INDEL;HRUN=3;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtgtttattac/gac|GVYY142D|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 22193 . AATT A 13617.0 PASS DP=458;AF=0.923581;SB=24;DP4=78,133,208,215;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattta/ata|NL211I|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22204 . T TGAGCCAGAA 9573.0 PASS DP=385;AF=0.72987;SB=0;DP4=38,45,128,153;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGAAGAt|D215EPED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22204 . T TGAGCCAGTA 71.0 PASS DP=385;AF=0.01039;SB=12;DP4=38,45,4,0;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGTAGAt|D215EPVD|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGTA|INFO_REALIGN_3_PRIME) +NC_045512.2 22578 . G A 32390.0 PASS DP=920;AF=0.944565;SB=0;DP4=0,0,463,452;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGt/gAt|G339D|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22673 . T C 16172.0 PASS DP=483;AF=0.900621;SB=7;DP4=2,0,193,283;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tcc/Ccc|S371P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22674 . C T 15572.0 PASS DP=483;AF=0.873706;SB=0;DP4=0,0,196,280;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S371F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22679 . T C 16856.0 PASS DP=511;AF=0.886497;SB=11;DP4=3,0,208,297;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Cca|S373P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22686 . C T 17918.0 PASS DP=515;AF=0.920388;SB=3;DP4=1,0,210,304;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S375F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22992 . G A 6583.0 PASS DP=203;AF=0.901478;SB=0;DP4=0,0,105,97;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGc/aAc|S477N|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22995 . C A 7019.0 PASS DP=213;AF=0.910798;SB=0;DP4=0,0,110,103;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T478K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23013 . A C 10718.0 PASS DP=313;AF=0.910543;SB=0;DP4=0,0,168,145;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gCa|E484A|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23040 . A G 12315.0 PASS DP=376;AF=0.880319;SB=0;DP4=2,1,191,182;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q493R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23048 . G A 15700.0 PASS DP=440;AF=0.945455;SB=0;DP4=0,0,225,214;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G496S|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23055 . A G 13956.0 PASS DP=452;AF=0.845133;SB=0;DP4=0,0,228,218;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q498R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23063 . A T 19708.0 PASS DP=556;AF=0.953237;SB=0;DP4=0,0,293,263;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aat/Tat|N501Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23075 . T C 17361.0 PASS DP=563;AF=0.845471;SB=12;DP4=5,0,286,271;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y505H|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23202 . C A 29018.0 PASS DP=831;AF=0.922984;SB=0;DP4=0,1,402,421;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T547K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23403 . A G 49314.0 PASS DP=1784;AF=0.867713;SB=3;DP4=4,2,875,895;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D614G|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23525 . C T 49314.0 PASS DP=1502;AF=0.913449;SB=0;DP4=1,1,706,790;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cat/Tat|H655Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23540 . T C 80.0 PASS DP=1413;AF=0.004954;SB=2;DP4=647,753,6,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tat/Cat|Y660H|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23599 . T G 24616.0 PASS DP=734;AF=0.916894;SB=1;DP4=3,2,326,403;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaG|N679K|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23604 . C A 20646.0 PASS DP=595;AF=0.934454;SB=3;DP4=1,0,258,335;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cAt|P681H|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23948 . G T 15732.0 PASS DP=478;AF=0.868201;SB=0;DP4=0,0,251,214;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gat/Tat|D796Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24130 . C A 16664.0 PASS DP=506;AF=0.87747;SB=2;DP4=0,2,231,270;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaC/aaA|N856K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24424 . A T 27727.0 PASS DP=818;AF=0.914425;SB=0;DP4=1,2,407,406;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caT|Q954H|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24469 . T A 43387.0 PASS DP=1249;AF=0.928743;SB=0;DP4=3,3,628,611;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N969K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24503 . C T 44381.0 PASS DP=1280;AF=0.923437;SB=0;DP4=1,1,623,650;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L981F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25000 . C T 15366.0 PASS DP=496;AF=0.836694;SB=11;DP4=1,6,247,238;EFF=SYNONYMOUS_CODING(LOW|SILENT|gaC/gaT|D1146|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25584 . C T 34503.0 PASS DP=1032;AF=0.891473;SB=3;DP4=1,0,503,521;EFF=SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T64|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 26215 . T C 146.0 PASS DP=979;AF=0.010215;SB=0;DP4=470,494,6,6;EFF=SYNONYMOUS_CODING(LOW|SILENT|Ttg/Ctg|L275|275|ORF3a|protein_coding|CODING|GU280_gp03|1|C) +NC_045512.2 26270 . C T 29169.0 PASS DP=860;AF=0.898837;SB=0;DP4=0,0,393,465;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aTa|T9I|75|E|protein_coding|CODING|GU280_gp04|1|T) +NC_045512.2 26530 . A G 3877.0 PASS DP=126;AF=0.84127;SB=0;DP4=0,0,60,66;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D3G|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26577 . C G 1326.0 PASS DP=41;AF=0.878049;SB=0;DP4=1,1,19,20;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Gaa|Q19E|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26709 . G A 3475.0 PASS DP=110;AF=0.854545;SB=0;DP4=0,0,50,60;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A63T|222|M|protein_coding|CODING|GU280_gp05|1|A) +NC_045512.2 27259 . A C 26760.0 PASS DP=818;AF=0.887531;SB=3;DP4=0,1,430,383;EFF=SYNONYMOUS_CODING(LOW|SILENT|Agg/Cgg|R20|61|ORF6|protein_coding|CODING|GU280_gp06|1|C) +NC_045512.2 27263 . CTTTTAAAGTTTCCATTTGGAATCTTGA C 67.0 PASS DP=909;AF=0.0044;SB=0;DP4=484,421,2,2;INDEL;HRUN=4;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||tttaaagtttccatttggaatcttgattac/tac|FKVSIWNLDY22Y|61|ORF6|protein_coding|CODING|GU280_gp06|1|C|INFO_REALIGN_3_PRIME) +NC_045512.2 27807 . C T 28196.0 PASS DP=816;AF=0.935049;SB=0;DP4=0,0,395,420;EFF=SYNONYMOUS_CODING(LOW|SILENT|Cta/Tta|L18|43|ORF7b|protein_coding|CODING|GU280_gp08|1|T) +NC_045512.2 28271 . A T 37938.0 PASS DP=1087;AF=0.930083;SB=0;DP4=0,1,530,552 +NC_045512.2 28311 . C T 34465.0 PASS DP=1148;AF=0.818815;SB=2;DP4=3,6,535,588;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cTc|P13L|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28361 . GGAGAACGCA G 28153.0 PASS DP=1041;AF=0.813641;SB=0;DP4=94,104,398,449;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggagaacgcagt/ggt|GERS30G|419|N|protein_coding|CODING|GU280_gp10|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 28363 . AGAACGCAGT A 126.0 PASS DP=870;AF=0.010345;SB=29;DP4=406,460,9,0;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gaacgcagtggg/ggg|ERSG31G|419|N|protein_coding|CODING|GU280_gp10|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 28754 . C T 31727.0 PASS DP=931;AF=0.90333;SB=0;DP4=1,1,471,454;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L161F|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28881 . G A 18291.0 PASS DP=529;AF=0.922495;SB=0;DP4=0,0,265,264;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGg/aAg|R203K|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28882 . G A 16928.0 PASS DP=523;AF=0.869981;SB=3;DP4=0,1,259,254;EFF=SYNONYMOUS_CODING(LOW|SILENT|agG/agA|R203|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28883 . G C 18465.0 PASS DP=524;AF=0.946565;SB=3;DP4=2,0,260,262;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gga/Cga|G204R|419|N|protein_coding|CODING|GU280_gp10|1|C) diff --git a/example_data/example_mave_data/input/sample-05.vcf b/example_data/example_mave_data/input/sample-05.vcf new file mode 100644 index 0000000..1e0ccb2 --- /dev/null +++ b/example_data/example_mave_data/input/sample-05.vcf @@ -0,0 +1,160 @@ +##fileformat=VCFv4.0 +##FILTER= +##fileDate=20240114 +##source=lofreq call --verbose --ref reference.fa --call-indels --min-cov 5 --max-depth 1000000 --min-bq 30 --min-alt-bq 30 --min-mq 20 --max-mq 255 --min-jq 0 --min-alt-jq 0 --def-alt-jq 0 --sig 0.0005 --bonf dynamic --no-default-filter --no-default-filter -r NC_045512.2:1-7475 -o /data/jwd02f/main/066/348/66348160/tmp/lofreq2_call_parallelj76ljs3e/0.vcf.gz reads.bam +##reference=reference.fa +##INFO= +##INFO= --min-bq among all bases at the site"> +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##INFO= +##bcftools_annotateVersion=1.10.2+htslib-1.10.2 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites -AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 20:42:25 2024 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites +AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 20:43:28 2024 +##SnpEffVersion="4.5covid19 (build 2020-04-15 22:26), by Pablo Cingolani" +##SnpEffCmd="SnpEff -i vcf -o vcf -formatEff -classic -no-downstream -no-intergenic -no-upstream -stats /data/jwd02f/main/066/348/66348340/outputs/dataset_e414f2b7-2b1b-4ea6-97a7-a1580144d8d2.dat NC_045512.2 /data/dnb09/galaxy_db/files/2/5/f/dataset_25f072f9-1bb7-4d2d-b4ab-585f015e71dc.dat " +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +NC_045512.2 241 . C T 49314.0 PASS DP=2246;AF=0.943455;SB=4;DP4=3,1,1113,1127 +NC_045512.2 506 . CATGGTCATGTT C 98.0 PASS DP=5493;AF=0.001456;SB=0;DP4=2769,2770,4,4;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||catgttatggtt/|HVMV83|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||catgttatggtt/|HVMV83|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|C|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||catgttatggtt/|HVMV83|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|C|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||catgttatggtt/|HVMV83|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 507 . ATGGTCATGTTATGGT A 83.0 PASS DP=5498;AF=0.001273;SB=0;DP4=2746,2746,3,4;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 509 . GGTCATGTTA G 424.0 PASS DP=5467;AF=0.004756;SB=0;DP4=2708,2711,13,13;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G) +NC_045512.2 509 . GGTCATGTTATGGTT G 487.0 PASS DP=5467;AF=0.005305;SB=0;DP4=2708,2711,14,15;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 509 . GGTCATGTT G 66.0 PASS DP=5467;AF=0.001097;SB=0;DP4=2708,2711,3,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 514 . TGTTATG T 271.0 PASS DP=5435;AF=0.003312;SB=0;DP4=2707,2715,9,9;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||atggtt/|MV85|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||atggtt/|MV85|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME) +NC_045512.2 515 . GTTA G 67.0 PASS DP=5431;AF=0.001105;SB=0;DP4=2709,2719,3,3;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttatg/gtg|VM84V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttatg/gtg|VM84V|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttatg/gtg|VM84V|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttatg/gtg|VM84V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 515 . GTTATGGTT G 97.0 PASS DP=5431;AF=0.001473;SB=0;DP4=2709,2719,4,4;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||gttatggtt/|VMV84|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),FRAME_SHIFT(HIGH||gttatggtt/|VMV84|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||gttatggtt/|VMV84|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||gttatggtt/|VMV84|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 517 . TATG T 97.0 PASS DP=5381;AF=0.001487;SB=0;DP4=2688,2697,4,4;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||atg/|M85|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),CODON_DELETION(MODERATE||atg/|M85|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_DELETION(MODERATE||atg/|M85|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_DELETION(MODERATE||atg/|M85|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T) +NC_045512.2 518 . ATGGTTG A 68.0 PASS DP=5289;AF=0.001134;SB=0;DP4=2688,2697,3,3;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||atggttgag/aag|MVE85K|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||atggttgag/aag|MVE85K|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||atggttgag/aag|MVE85K|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||atggttgag/aag|MVE85K|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A) +NC_045512.2 582 . T C 103.0 PASS DP=4894;AF=0.002656;SB=5;DP4=2379,2449,13,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTc/gCc|V106A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTc/gCc|V106A|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|C|WARNING_TRANSCRIPT_NO_STOP_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTc/gCc|V106A|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|C|WARNING_TRANSCRIPT_NO_STOP_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTc/gCc|V106A|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C) +NC_045512.2 593 . C T 150.0 PASS DP=4709;AF=0.003398;SB=8;DP4=2289,2383,18,10;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cat/Tat|H110Y|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cat/Tat|H110Y|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cat/Tat|H110Y|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cat/Tat|H110Y|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T) +NC_045512.2 683 . CTA C 75.0 PASS DP=3889;AF=0.001543;SB=0;DP4=1906,2022,3,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||cta/|L140|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),FRAME_SHIFT(HIGH||cta/|L140|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|C|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||cta/|L140|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|C|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||cta/|L140|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 746 . TG T 72.0 PASS DP=2120;AF=0.002358;SB=0;DP4=1071,1044,3,2;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||tgg/|W161|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgg/|W161|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgg/|W161|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgg/|W161|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 1026 . C CT 217.0 PASS DP=2290;AF=0.005677;SB=0;DP4=1198,1079,7,6;INDEL;HRUN=4;EFF=FRAME_SHIFT+STOP_GAINED(HIGH||gaa/Tgaa|E256*?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT+STOP_GAINED(HIGH||gaa/Tgaa|E256*?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT+STOP_GAINED(HIGH||gaa/Tgaa|E76*?|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT+STOP_GAINED(HIGH||gaa/Tgaa|E76*?|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14);NMD=(ORF1ab|GU280_gp01|28|0.04) +NC_045512.2 1135 . G GA 74.0 PASS DP=2780;AF=0.002158;SB=0;DP4=1399,1395,3,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aag/aaAg|K292K?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|GA|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/aaAg|K292K?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|GA|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/aaAg|K112K?|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|GA|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/aaAg|K112K?|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|GA|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.11) +NC_045512.2 2330 . T A 419.0 PASS DP=2858;AF=0.010847;SB=0;DP4=1351,1414,19,18;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2434 . CAG C 69.0 PASS DP=2617;AF=0.001911;SB=0;DP4=1197,1430,2,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||gaa/|E725|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gaa/|E725|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gaa/|E545|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gaa/|E545|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 2832 . A G 49314.0 PASS DP=2369;AF=0.921064;SB=0;DP4=1,1,1108,1250;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3037 . C T 49314.0 PASS DP=1855;AF=0.930997;SB=3;DP4=1,0,884,959;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3545 . AATG A 94.0 PASS DP=3388;AF=0.002066;SB=1;DP4=1689,1697,4,3;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aatgga/aga|NG1094R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aatgga/aga|NG1094R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aatgga/aga|NG276R|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aatgga/aga|NG276R|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3862 . T A 178.0 PASS DP=451;AF=0.022173;SB=1;DP4=220,219,7,5;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V1199|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V1199|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V381|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V381|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 4160 . G T 182.0 PASS DP=1906;AF=0.00787;SB=2;DP4=936,937,13,9;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtg/Ttg|V1299L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtg/Ttg|V1299L|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtg/Ttg|V481L|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtg/Ttg|V481L|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5386 . T G 49314.0 PASS DP=3743;AF=0.878707;SB=5;DP4=9,5,1850,1865;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5743 . G C 1108.0 PASS DP=3233;AF=0.022889;SB=1;DP4=1573,1551,46,50;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5744 . T C 1101.0 PASS DP=3230;AF=0.02291;SB=2;DP4=1569,1566,49,43;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6512 . AGTT A 49314.0 PASS DP=2353;AF=0.99575;SB=6;DP4=8,3,1201,1142;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6653 . GTTAATAGTGTCCCTTGGGATACTATAGCTA G 99.0 PASS DP=3142;AF=0.002228;SB=1;DP4=1561,1581,4,3;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaatagtgtcccttgggatactatagctaat/gat|VNSVPWDTIAN2130D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaatagtgtcccttgggatactatagctaat/gat|VNSVPWDTIAN2130D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaatagtgtcccttgggatactatagctaat/gat|VNSVPWDTIAN1312D|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaatagtgtcccttgggatactatagctaat/gat|VNSVPWDTIAN1312D|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 7019 . G GT 146.0 PASS DP=2956;AF=0.003383;SB=0;DP4=1436,1530,5,5;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tta/ttTa|L2253F?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|GT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/ttTa|L2253F?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|GT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/ttTa|L1435F?|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|GT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/ttTa|L1435F?|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|GT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 8393 . G A 49314.0 PASS DP=2771;AF=0.926019;SB=4;DP4=1,3,1529,1230;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10029 . C T 49314.0 PASS DP=3230;AF=0.878019;SB=1;DP4=5,3,1606,1592;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10069 . A G 1516.0 PASS DP=2739;AF=0.029938;SB=1;DP4=1275,1369,40,47;EFF=SYNONYMOUS_CODING(LOW|SILENT|aaA/aaG|K3268|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|aaA/aaG|K3268|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|aaA/aaG|K5|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|aaA/aaG|K5|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10449 . C A 49314.0 PASS DP=3662;AF=0.895958;SB=2;DP4=4,7,1770,1856;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10484 . T G 265.0 PASS DP=2480;AF=0.008871;SB=2;DP4=1285,1165,13,15;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10541 . C A 96.0 PASS DP=2752;AF=0.00436;SB=18;DP4=1356,1344,9,24;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10660 . TA T 117.0 PASS DP=3002;AF=0.002665;SB=0;DP4=1469,1534,4,4;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||aat/|N3466|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aat/|N3466|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aat/|N203|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aat/|N203|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11088 . A T 103.0 PASS DP=3622;AF=0.003037;SB=98;DP4=1811,1759,42,2;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gTa|E3608V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gTa|E3608V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gTa|E39V|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gTa|E39V|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11095 . C T 118.0 PASS DP=2741;AF=0.004743;SB=0;DP4=1422,1293,10,8;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcC/gcT|A3610|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|gcC/gcT|A3610|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|gcC/gcT|A41|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gcC/gcT|A41|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11270 . ATGGTT A 73.0 PASS DP=3921;AF=0.00153;SB=0;DP4=1907,2044,3,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||atggtt/|MV3669|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),FRAME_SHIFT(HIGH||atggtt/|MV3669|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),FRAME_SHIFT(HIGH||atggtt/|MV100|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),FRAME_SHIFT(HIGH||atggtt/|MV100|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11279 . ACTAGTTTGT A 74.0 PASS DP=3660;AF=0.002732;SB=32;DP4=1732,1921,10,0;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||agtttgtct/|SLS3673|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||agtttgtct/|SLS3673|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||agtttgtct/|SLS104|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||agtttgtct/|SLS104|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 11282 . AGTTTGTCTG A 49314.0 PASS DP=3563;AF=0.920011;SB=11;DP4=149,134,1543,1735;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 11537 . A G 49314.0 PASS DP=4961;AF=0.903044;SB=1;DP4=3,2,2442,2504;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11847 . A C 89.0 PASS DP=2709;AF=0.003691;SB=1;DP4=1339,1350,6,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAa/aCa|K3861T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAa/aCa|K3861T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAa/aCa|K2T|82|ORF1ab|protein_coding|CODING|YP_009725303.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAa/aCa|K2T|82|ORF1ab|protein_coding|CODING|YP_009742614.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 12004 . A G 80.0 PASS DP=3213;AF=0.002801;SB=0;DP4=1646,1544,5,5;EFF=SYNONYMOUS_CODING(LOW|SILENT|tcA/tcG|S3913|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|tcA/tcG|S3913|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|tcA/tcG|S54|82|ORF1ab|protein_coding|CODING|YP_009725303.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|tcA/tcG|S54|82|ORF1ab|protein_coding|CODING|YP_009742614.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 12427 . TG T 85.0 PASS DP=2764;AF=0.002171;SB=0;DP4=1385,1375,3,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggt/|G4055|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggt/|G4055|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggt/|G113|197|ORF1ab|protein_coding|CODING|YP_009725304.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggt/|G113|197|ORF1ab|protein_coding|CODING|YP_009742615.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 12484 . C T 82.0 PASS DP=2486;AF=0.00362;SB=1;DP4=1243,1231,6,4;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtC/gtT|V4073|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|gtC/gtT|V4073|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|gtC/gtT|V131|197|ORF1ab|protein_coding|CODING|YP_009725304.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtC/gtT|V131|197|ORF1ab|protein_coding|CODING|YP_009742615.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 12661 . G T 88.0 PASS DP=3466;AF=0.002885;SB=0;DP4=1705,1719,14,14;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|agG/agT|R4132S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|agG/agT|R4132S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|agG/agT|R190S|197|ORF1ab|protein_coding|CODING|YP_009725304.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|agG/agT|R190S|197|ORF1ab|protein_coding|CODING|YP_009742615.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13195 . T C 49314.0 PASS DP=5323;AF=0.904565;SB=1;DP4=4,2,2815,2486;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13571 . G T 87.0 PASS DP=1237;AF=0.005659;SB=0;DP4=655,567,5,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGt/gTt|G4436V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGt/gTt|G44V|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 14407 . CCTACAAG C 77.0 PASS DP=2853;AF=0.002103;SB=0;DP4=1504,1419,3,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||cctacaagt/|PTS4715|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),FRAME_SHIFT(HIGH||cctacaagt/|PTS323|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 14408 . C T 49314.0 PASS DP=2853;AF=0.930249;SB=0;DP4=1,1,1461,1374;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P4715L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P323L|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 14848 . CTATTTG C 97.0 PASS DP=1729;AF=0.00347;SB=0;DP4=870,869,3,3;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||tttgta/|FV4863|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||tttgta/|FV471|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 15157 . C A 288.0 PASS DP=2851;AF=0.007717;SB=1237;DP4=1472,1023,0,355;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Aaa|Q4965K|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Aaa|Q573K|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15173 . C A 229.0 PASS DP=2922;AF=0.00616;SB=813;DP4=1497,1176,0,244;EFF=STOP_GAINED(HIGH|NONSENSE|tCa/tAa|S4970*|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),STOP_GAINED(HIGH|NONSENSE|tCa/tAa|S578*|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15240 . C T 49314.0 PASS DP=2750;AF=0.937091;SB=2;DP4=2,1,1307,1433;EFF=SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N4992|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N600|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15906 . G A 158.0 PASS DP=4133;AF=0.003871;SB=0;DP4=2055,2051,9,9;EFF=SYNONYMOUS_CODING(LOW|SILENT|caG/caA|Q5214|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),SYNONYMOUS_CODING(LOW|SILENT|caG/caA|Q822|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15983 . TA T 68.0 PASS DP=3442;AF=0.001743;SB=0;DP4=1791,1646,3,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aca/|T5242|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aca/|T850|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 16022 . CT C 75.0 PASS DP=3898;AF=0.001539;SB=0;DP4=2037,2056,3,3;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||tta/|L5254|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L862|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 16597 . AT A 85.0 PASS DP=2158;AF=0.00278;SB=0;DP4=1073,1079,3,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tta/|L5446|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L122|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 17200 . TTAAAA T 82.0 PASS DP=3004;AF=0.001997;SB=0;DP4=1501,1497,3,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||aaatat/|KY5647|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaatat/|KY323|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 18163 . A G 49314.0 PASS DP=1502;AF=0.91478;SB=0;DP4=0,1,746,747;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I5967V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I42V|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18659 . GTT G 77.0 PASS DP=3278;AF=0.00183;SB=0;DP4=1692,1598,3,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||tgttgt/|CC6132|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),FRAME_SHIFT(HIGH||tgttgt/|CC207|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 18739 . GATTA G 79.0 PASS DP=3391;AF=0.001769;SB=0;DP4=1694,1689,3,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||gattac/|DY6159|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),FRAME_SHIFT(HIGH||gattac/|DY234|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 18742 . TACGTCTA T 79.0 PASS DP=3345;AF=0.001794;SB=0;DP4=1673,1670,3,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||tacgtctat/|YVY6160|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),FRAME_SHIFT(HIGH||tacgtctat/|YVY235|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 19983 . C T 81.0 PASS DP=3938;AF=0.003047;SB=3;DP4=1972,1923,11,15;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtC/gtT|V6573|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|gtC/gtT|V121|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 20114 . T A 98.0 PASS DP=2158;AF=0.004171;SB=109;DP4=1058,1039,2,45;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTc/gAc|V6617D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTc/gAc|V165D|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 20296 . AAATT A 114.0 PASS DP=3199;AF=0.002501;SB=0;DP4=1599,1596,4,4;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||aaatta/|KL6678|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaatta/|KL226|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 20483 . C T 173.0 PASS DP=1904;AF=0.007353;SB=0;DP4=1009,869,9,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCt/tTt|S6740F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCt/tTt|S288F|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 21233 . C A 79.0 PASS DP=2467;AF=0.003648;SB=64;DP4=1226,1207,1,26;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCc/gAc|A6990D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCc/gAc|A192D|297|ORF1ab|protein_coding|CODING|YP_009725311.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 21622 . C A 80.0 PASS DP=3836;AF=0.002868;SB=4;DP4=1888,1920,6,11;EFF=SYNONYMOUS_CODING(LOW|SILENT|acC/acA|T20|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 21740 . TCCAATGTTACTTGGTTCCATGCTATACATGTCTCTGGGA T 223.0 PASS DP=2522;AF=0.005155;SB=0;DP4=1249,1260,6,7;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttacttggttccatgctatacatgtctctgggaccaatggt/ggt|VTWFHAIHVSGTNG62G|1273|S|protein_coding|CODING|GU280_gp02|1|T|INFO_REALIGN_3_PRIME) +NC_045512.2 21762 . C T 49314.0 PASS DP=2214;AF=0.923216;SB=3;DP4=0,2,1066,1119;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A67V|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21764 . ATACATG A 49314.0 PASS DP=2068;AF=0.98501;SB=3;DP4=13,18,1000,1037;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||atacatgtc/atc|IHV68I|1273|S|protein_coding|CODING|GU280_gp02|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 21846 . C T 49314.0 PASS DP=2082;AF=0.942363;SB=0;DP4=0,1,1003,1076;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T95I|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21985 . GGGTGTTTAT G 84.0 PASS DP=1570;AF=0.004459;SB=9;DP4=787,774,6,1;INDEL;HRUN=3;EFF=CODON_DELETION(MODERATE||ggtgtttat/|GVY142|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 21986 . GGTGTTTATT G 49272.0 PASS DP=1525;AF=0.987541;SB=2;DP4=35,29,759,747;INDEL;HRUN=3;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtgtttattac/gac|GVYY142D|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 22193 . AATT A 41683.0 PASS DP=1422;AF=0.909986;SB=68;DP4=244,400,654,640;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattta/ata|NL211I|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22204 . T TGAGCCAGAA 28146.0 PASS DP=1180;AF=0.713559;SB=6;DP4=136,161,421,421;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGAAGAt|D215EPED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22204 . T TGAGACAGAA 199.0 PASS DP=1180;AF=0.009322;SB=15;DP4=136,161,1,10;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGACAGAAGAt|D215ETED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGACAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22204 . T TGATCCAGAA 161.0 PASS DP=1180;AF=0.007627;SB=10;DP4=136,161,7,2;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||ctc/cCAGAAGATCtc|L216PEDL|1273|S|protein_coding|CODING|GU280_gp02|1|TGATCCAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22578 . G A 49314.0 PASS DP=3304;AF=0.95793;SB=3;DP4=0,1,1662,1636;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGt/gAt|G339D|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22583 . GTTT G 100.0 PASS DP=3268;AF=0.002448;SB=0;DP4=1640,1622,4,4;INDEL;HRUN=5;EFF=CODON_DELETION(MODERATE||ttt/|F342|1273|S|protein_coding|CODING|GU280_gp02|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 22673 . T C 49314.0 PASS DP=1718;AF=0.903376;SB=15;DP4=4,0,700,1001;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tcc/Ccc|S371P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22674 . C T 49314.0 PASS DP=1711;AF=0.863238;SB=0;DP4=1,1,702,984;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S371F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22679 . T C 49314.0 PASS DP=1811;AF=0.890116;SB=32;DP4=11,1,747,1041;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Cca|S373P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22685 . TC T 88.0 PASS DP=1830;AF=0.003279;SB=1;DP4=764,1060,3,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||tcc/|S375|1273|S|protein_coding|CODING|GU280_gp02|1|T|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 22686 . C T 49314.0 PASS DP=1830;AF=0.930601;SB=0;DP4=2,3,762,1055;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S375F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22992 . G A 24970.0 PASS DP=754;AF=0.928382;SB=0;DP4=0,0,402,349;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGc/aAc|S477N|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22995 . C A 26297.0 PASS DP=773;AF=0.934023;SB=0;DP4=0,0,412,361;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T478K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23013 . A C 37973.0 PASS DP=1083;AF=0.928901;SB=0;DP4=2,1,571,508;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gCa|E484A|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23040 . A G 41466.0 PASS DP=1242;AF=0.896135;SB=0;DP4=3,2,636,598;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q493R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23048 . G A 49314.0 PASS DP=1461;AF=0.960986;SB=0;DP4=1,1,757,701;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G496S|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23055 . A G 48277.0 PASS DP=1505;AF=0.869767;SB=0;DP4=0,0,774,721;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q498R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23063 . A T 49314.0 PASS DP=1811;AF=0.967973;SB=0;DP4=1,0,943,865;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aat/Tat|N501Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23075 . T C 49314.0 PASS DP=1836;AF=0.90305;SB=17;DP4=7,0,948,879;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y505H|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23202 . C A 49314.0 PASS DP=2798;AF=0.931022;SB=0;DP4=0,1,1383,1400;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T547K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23403 . A G 49314.0 PASS DP=5180;AF=0.897104;SB=19;DP4=15,4,2546,2597;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D614G|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23525 . C T 49314.0 PASS DP=4496;AF=0.93105;SB=3;DP4=1,0,2148,2341;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cat/Tat|H655Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23599 . T G 49314.0 PASS DP=2390;AF=0.932218;SB=1;DP4=3,2,1101,1280;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaG|N679K|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23604 . C A 49314.0 PASS DP=2025;AF=0.937284;SB=0;DP4=1,2,920,1095;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cAt|P681H|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23854 . C A 643.0 PASS DP=17;AF=1;SB=0;DP4=0,0,8,9;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaC/aaA|N764K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23948 . G T 28897.0 PASS DP=890;AF=0.859551;SB=0;DP4=0,0,434,441;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gat/Tat|D796Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24025 . ACTT A 97.0 PASS DP=1549;AF=0.003873;SB=0;DP4=724,825,3,3;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||ctt/|L822|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24130 . C A 49314.0 PASS DP=1674;AF=0.916368;SB=0;DP4=1,2,765,886;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaC/aaA|N856K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24424 . A T 49314.0 PASS DP=2734;AF=0.940746;SB=14;DP4=1,7,1367,1358;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caT|Q954H|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24469 . T A 49314.0 PASS DP=4027;AF=0.939409;SB=0;DP4=1,1,2016,1999;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N969K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24503 . C T 49314.0 PASS DP=4060;AF=0.932512;SB=0;DP4=1,2,1971,2069;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L981F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24858 . G A 112.0 PASS DP=2435;AF=0.004517;SB=38;DP4=1240,1162,4,23;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGc/gAc|G1099D|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24866 . TG T 86.0 PASS DP=2511;AF=0.002389;SB=0;DP4=1291,1226,3,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||tgg/|W1102|1273|S|protein_coding|CODING|GU280_gp02|1|T|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 24942 . A T 131.0 PASS DP=2150;AF=0.006047;SB=0;DP4=1068,1064,8,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gTt|D1127V|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25000 . C T 49314.0 PASS DP=1739;AF=0.890742;SB=5;DP4=2,5,867,860;EFF=SYNONYMOUS_CODING(LOW|SILENT|gaC/gaT|D1146|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25584 . C T 49314.0 PASS DP=3424;AF=0.922313;SB=3;DP4=1,0,1702,1719;EFF=SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T64|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 26194 . A T 106.0 PASS DP=3464;AF=0.003753;SB=2;DP4=1692,1715,14,11;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Acg/Tcg|T268S|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 26270 . C T 49314.0 PASS DP=3121;AF=0.93784;SB=0;DP4=3,3,1458,1645;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aTa|T9I|75|E|protein_coding|CODING|GU280_gp04|1|T) +NC_045512.2 26530 . A G 33497.0 PASS DP=1009;AF=0.908821;SB=1;DP4=2,4,484,514;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D3G|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26577 . C G 13027.0 PASS DP=416;AF=0.872596;SB=0;DP4=16,16,185,198;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Gaa|Q19E|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26709 . G A 33637.0 PASS DP=1057;AF=0.856197;SB=0;DP4=0,0,494,558;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A63T|222|M|protein_coding|CODING|GU280_gp05|1|A) +NC_045512.2 27259 . A C 49314.0 PASS DP=2596;AF=0.901387;SB=0;DP4=1,1,1368,1219;EFF=SYNONYMOUS_CODING(LOW|SILENT|Agg/Cgg|R20|61|ORF6|protein_coding|CODING|GU280_gp06|1|C) +NC_045512.2 27800 . C A 99.0 PASS DP=2812;AF=0.003912;SB=28;DP4=1323,1448,25,8;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcC/gcA|A15|43|ORF7b|protein_coding|CODING|GU280_gp08|1|A) +NC_045512.2 27807 . C T 49314.0 PASS DP=2789;AF=0.933668;SB=0;DP4=1,1,1347,1432;EFF=SYNONYMOUS_CODING(LOW|SILENT|Cta/Tta|L18|43|ORF7b|protein_coding|CODING|GU280_gp08|1|T) +NC_045512.2 28214 . C CT 173.0 PASS DP=2046;AF=0.005376;SB=1;DP4=1013,1034,6,5;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||tta/ttTa|L109F?|121|ORF8|protein_coding|CODING|GU280_gp09|1|CT|INFO_REALIGN_3_PRIME);LOF=(ORF8|GU280_gp09|1|1.00) +NC_045512.2 28253 . CA C 80.0 PASS DP=3148;AF=0.001906;SB=0;DP4=1576,1571,3,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||atc/|I121|121|ORF8|protein_coding|CODING|GU280_gp09|1|C) +NC_045512.2 28271 . A T 49314.0 PASS DP=3633;AF=0.944674;SB=0;DP4=2,3,1796,1824 +NC_045512.2 28311 . C T 49314.0 PASS DP=3776;AF=0.851165;SB=27;DP4=4,20,1810,1914;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cTc|P13L|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28361 . GGAGAACGCA G 49314.0 PASS DP=3397;AF=0.815131;SB=3;DP4=315,323,1319,1450;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggagaacgcagt/ggt|GERS30G|419|N|protein_coding|CODING|GU280_gp10|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 28363 . AGAACGCAGT A 375.0 PASS DP=2825;AF=0.010265;SB=76;DP4=1341,1463,28,1;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gaacgcagtggg/ggg|ERSG31G|419|N|protein_coding|CODING|GU280_gp10|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 28541 . G T 564.0 PASS DP=3086;AF=0.012962;SB=1;DP4=1561,1465,25,20;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Tct|A90S|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28881 . G A 49314.0 PASS DP=2000;AF=0.9365;SB=0;DP4=2,3,992,999;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGg/aAg|R203K|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28882 . G A 49314.0 PASS DP=1993;AF=0.911691;SB=0;DP4=0,0,989,989;EFF=SYNONYMOUS_CODING(LOW|SILENT|agG/agA|R203|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28883 . G C 49314.0 PASS DP=1996;AF=0.943888;SB=6;DP4=2,0,988,1003;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gga/Cga|G204R|419|N|protein_coding|CODING|GU280_gp10|1|C) +NC_045512.2 28987 . CCAA C 216.0 PASS DP=1693;AF=0.007088;SB=0;DP4=856,868,6,6;INDEL;HRUN=2;EFF=CODON_DELETION(MODERATE||caa/|Q242|419|N|protein_coding|CODING|GU280_gp10|1|C|INFO_REALIGN_3_PRIME) +NC_045512.2 29518 . C T 44476.0 PASS DP=1331;AF=0.909842;SB=3;DP4=0,1,700,622;EFF=SYNONYMOUS_CODING(LOW|SILENT|gaC/gaT|D415|419|N|protein_coding|CODING|GU280_gp10|1|T) diff --git a/example_data/example_mave_data/input/sample-06.vcf b/example_data/example_mave_data/input/sample-06.vcf new file mode 100644 index 0000000..2a3ecf6 --- /dev/null +++ b/example_data/example_mave_data/input/sample-06.vcf @@ -0,0 +1,156 @@ +##fileformat=VCFv4.0 +##FILTER= +##fileDate=20240114 +##source=lofreq call --verbose --ref reference.fa --call-indels --min-cov 5 --max-depth 1000000 --min-bq 30 --min-alt-bq 30 --min-mq 20 --max-mq 255 --min-jq 0 --min-alt-jq 0 --def-alt-jq 0 --sig 0.0005 --bonf dynamic --no-default-filter --no-default-filter -r NC_045512.2:1-7475 -o /data/jwd02f/main/066/348/66348161/tmp/lofreq2_call_parallelyg27hph0/0.vcf.gz reads.bam +##reference=reference.fa +##INFO= +##INFO= --min-bq among all bases at the site"> +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##INFO= +##bcftools_annotateVersion=1.10.2+htslib-1.10.2 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites -AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 21:36:29 2024 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites +AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 21:37:31 2024 +##SnpEffVersion="4.5covid19 (build 2020-04-15 22:26), by Pablo Cingolani" +##SnpEffCmd="SnpEff -i vcf -o vcf -formatEff -classic -no-downstream -no-intergenic -no-upstream -stats /data/jwd05e/main/066/348/66348341/outputs/dataset_02ce699b-43e1-4510-83c8-9eba98cb6aa4.dat NC_045512.2 /data/dnb09/galaxy_db/files/f/5/5/dataset_f55c6fe0-c69e-4d2f-8951-0548b6f6bb8c.dat " +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +NC_045512.2 241 . C T 30837.0 PASS DP=885;AF=0.946893;SB=3;DP4=1,0,438,445 +NC_045512.2 443 . GT G 124.0 PASS DP=3300;AF=0.002727;SB=0;DP4=1685,1608,5,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttg/|L61|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 507 . ATGGTCATGTTATGGT A 341.0 PASS DP=3799;AF=0.005265;SB=0;DP4=1885,1894,10,10;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 509 . GGTCATGTTATGGTT G 779.0 PASS DP=3772;AF=0.010604;SB=0;DP4=1852,1862,20,20;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 509 . GGTCATGTT G 276.0 PASS DP=3772;AF=0.004772;SB=0;DP4=1852,1862,9,9;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 509 . GGTCATGTTA G 110.0 PASS DP=3772;AF=0.002121;SB=0;DP4=1852,1862,4,4;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatg/gtg|GHVM82V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G) +NC_045512.2 514 . TGTTATG T 183.0 PASS DP=3791;AF=0.003165;SB=0;DP4=1882,1897,6,6;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||atggtt/|MV85|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||atggtt/|MV85|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME) +NC_045512.2 517 . TATG T 162.0 PASS DP=3751;AF=0.002933;SB=0;DP4=1866,1880,5,6;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||atg/|M85|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),CODON_DELETION(MODERATE||atg/|M85|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_DELETION(MODERATE||atg/|M85|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_DELETION(MODERATE||atg/|M85|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T) +NC_045512.2 518 . ATGGTT A 75.0 PASS DP=3684;AF=0.001629;SB=0;DP4=1867,1879,3,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||atggtt/|MV85|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),FRAME_SHIFT(HIGH||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||atggtt/|MV85|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 685 . AAAGTCATTT A 162.0 PASS DP=2587;AF=0.003865;SB=0;DP4=1268,1341,5,5;INDEL;HRUN=3;EFF=CODON_DELETION(MODERATE||aagtcattt/|KSF141|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_DELETION(MODERATE||aagtcattt/|KSF141|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_DELETION(MODERATE||aagtcattt/|KSF141|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_DELETION(MODERATE||aagtcattt/|KSF141|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A) +NC_045512.2 1026 . C CT 236.0 PASS DP=1686;AF=0.007711;SB=0;DP4=885,788,7,6;INDEL;HRUN=4;EFF=FRAME_SHIFT+STOP_GAINED(HIGH||gaa/Tgaa|E256*?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT+STOP_GAINED(HIGH||gaa/Tgaa|E256*?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT+STOP_GAINED(HIGH||gaa/Tgaa|E76*?|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT+STOP_GAINED(HIGH||gaa/Tgaa|E76*?|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14);NMD=(ORF1ab|GU280_gp01|28|0.04) +NC_045512.2 1218 . C T 78.0 PASS DP=1653;AF=0.004235;SB=1;DP4=782,860,5,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCa/tTa|S318L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCa/tTa|S318L|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCa/tTa|S138L|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCa/tTa|S138L|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 1495 . G GT 99.0 PASS DP=1163;AF=0.005159;SB=0;DP4=582,587,3,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ttc/ttTc|F411F?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|GT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttc/ttTc|F411F?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|GT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttc/ttTc|F231F?|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|GT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttc/ttTc|F231F?|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|GT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 1957 . G T 49314.0 PASS DP=2748;AF=0.92067;SB=4;DP4=1,3,1389,1349;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaG/aaT|K564N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaG/aaT|K564N|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaG/aaT|K384N|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaG/aaT|K384N|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2330 . T A 126.0 PASS DP=2123;AF=0.005181;SB=8;DP4=982,1067,12,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2832 . A G 49314.0 PASS DP=1451;AF=0.93315;SB=0;DP4=0,0,677,773;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3037 . C T 34025.0 PASS DP=970;AF=0.928866;SB=0;DP4=0,0,465,496;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3319 . A G 49314.0 PASS DP=1990;AF=0.91206;SB=1;DP4=4,5,999,981;EFF=SYNONYMOUS_CODING(LOW|SILENT|ccA/ccG|P1018|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|ccA/ccG|P1018|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|ccA/ccG|P200|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ccA/ccG|P200|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3545 . AATG A 227.0 PASS DP=2360;AF=0.005508;SB=0;DP4=1169,1180,6,7;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aatgga/aga|NG1094R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aatgga/aga|NG1094R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aatgga/aga|NG276R|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aatgga/aga|NG276R|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3862 . T A 123.0 PASS DP=159;AF=0.037736;SB=1;DP4=75,76,5,3;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V1199|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V1199|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V381|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V381|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 4528 . ATT A 61.0 PASS DP=1231;AF=0.003249;SB=0;DP4=612,611,2,2;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttttac/|FY1422|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttttac/|FY1422|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttttac/|FY604|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttttac/|FY604|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 4579 . TAACGATCTA T 66.0 PASS DP=1170;AF=0.003419;SB=0;DP4=568,598,2,2;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aacgatctaaat/aat|NDLN1439N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aacgatctaaat/aat|NDLN1439N|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aacgatctaaat/aat|NDLN621N|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aacgatctaaat/aat|NDLN621N|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 5183 . C A 91.0 PASS DP=2387;AF=0.00377;SB=66;DP4=1190,1147,6,39;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cct/Act|P1640T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cct/Act|P1640T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cct/Act|P822T|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cct/Act|P822T|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5386 . T G 49314.0 PASS DP=2396;AF=0.890234;SB=0;DP4=4,5,1183,1193;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5743 . G C 1003.0 PASS DP=2014;AF=0.030288;SB=0;DP4=980,962,33,34;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5744 . T C 976.0 PASS DP=2014;AF=0.029791;SB=0;DP4=974,961,37,34;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6512 . AGTT A 36682.0 PASS DP=1048;AF=0.996183;SB=0;DP4=3,3,556,488;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6696 . C CT 252.0 PASS DP=1842;AF=0.008143;SB=0;DP4=926,930,8,7;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ctt/Tctt|L2146S?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L2146S?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L1328S?|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L1328S?|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 7196 . AT A 76.0 PASS DP=1890;AF=0.002646;SB=0;DP4=993,894,3,2;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||tca/|S2312|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tca/|S2312|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tca/|S1494|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tca/|S1494|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 7246 . GTT G 82.0 PASS DP=1992;AF=0.003012;SB=0;DP4=994,1006,3,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||ttg/|L2329|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L2329|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L1511|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L1511|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 8393 . G A 49314.0 PASS DP=1851;AF=0.942193;SB=0;DP4=1,1,1021,826;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 9135 . T C 81.0 PASS DP=2070;AF=0.003865;SB=1;DP4=1023,1035,5,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTg/aCg|M2957T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTg/aCg|M2957T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTg/aCg|M194T|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTg/aCg|M194T|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 9621 . A T 77.0 PASS DP=2630;AF=0.003042;SB=157;DP4=1249,1321,51,0;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gTt|D3119V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gTt|D3119V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gTt|D356V|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gTt|D356V|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 9859 . ATT A 67.0 PASS DP=1043;AF=0.003835;SB=0;DP4=548,493,2,2;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||tta/|L3199|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),FRAME_SHIFT(HIGH||tta/|L3199|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),FRAME_SHIFT(HIGH||tta/|L436|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),FRAME_SHIFT(HIGH||tta/|L436|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 10029 . C T 49314.0 PASS DP=1721;AF=0.872748;SB=4;DP4=8,4,850,848;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10046 . GTT G 73.0 PASS DP=1638;AF=0.003053;SB=0;DP4=815,845,2,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttg/|L3262|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L3262|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L499|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L499|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 10408 . C T 150.0 PASS DP=1933;AF=0.006208;SB=8;DP4=886,1024,11,6;EFF=SYNONYMOUS_CODING(LOW|SILENT|taC/taT|Y3381|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|taC/taT|Y3381|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|taC/taT|Y118|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|taC/taT|Y118|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10449 . C A 49314.0 PASS DP=2214;AF=0.900181;SB=2;DP4=1,3,1060,1145;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10484 . T G 179.0 PASS DP=1291;AF=0.01007;SB=0;DP4=669,606,7,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10541 . C A 217.0 PASS DP=1502;AF=0.010652;SB=4;DP4=734,736,8,13;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11095 . C CT 266.0 PASS DP=1566;AF=0.009579;SB=0;DP4=815,736,8,7;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||tta/ttTa|L3612F?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/ttTa|L3612F?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/ttTa|L43F?|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/ttTa|L43F?|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11268 . ATATGGTTGATACTAGTTTGTCTGGTTTTAAGC A 90.0 PASS DP=2312;AF=0.002595;SB=0;DP4=1113,1195,3,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||atggttgatactagtttgtctggttttaagcta/|MVDTSLSGFKL3669|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||atggttgatactagtttgtctggttttaagcta/|MVDTSLSGFKL3669|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||atggttgatactagtttgtctggttttaagcta/|MVDTSLSGFKL100|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||atggttgatactagtttgtctggttttaagcta/|MVDTSLSGFKL100|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11282 . AGTTTGTCTG A 49314.0 PASS DP=2094;AF=0.920726;SB=13;DP4=89,73,903,1025;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 11485 . TA T 118.0 PASS DP=4016;AF=0.002241;SB=0;DP4=1998,2016,4,5;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||act/|T3741|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),FRAME_SHIFT(HIGH||act/|T3741|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),FRAME_SHIFT(HIGH||act/|T172|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),FRAME_SHIFT(HIGH||act/|T172|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11537 . A G 49314.0 PASS DP=3821;AF=0.897671;SB=0;DP4=2,2,1882,1928;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 12132 . CTTTTGCTACTGCTCAAGAAGCTTATGAGCAGGCTG C 65.0 PASS DP=2508;AF=0.001994;SB=1;DP4=1266,1259,2,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tttgctactgctcaagaagcttatgagcaggctgtt/|FATAQEAYEQAV3957|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tttgctactgctcaagaagcttatgagcaggctgtt/|FATAQEAYEQAV3957|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tttgctactgctcaagaagcttatgagcaggctgtt/|FATAQEAYEQAV15|197|ORF1ab|protein_coding|CODING|YP_009725304.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tttgctactgctcaagaagcttatgagcaggctgtt/|FATAQEAYEQAV15|197|ORF1ab|protein_coding|CODING|YP_009742615.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 12503 . T C 101.0 PASS DP=1240;AF=0.006452;SB=1;DP4=603,624,6,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tat/Cat|Y4080H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tat/Cat|Y4080H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tat/Cat|Y138H|197|ORF1ab|protein_coding|CODING|YP_009725304.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tat/Cat|Y138H|197|ORF1ab|protein_coding|CODING|YP_009742615.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13195 . T C 49314.0 PASS DP=3874;AF=0.920754;SB=1;DP4=4,2,2055,1805;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 14408 . C T 49314.0 PASS DP=1988;AF=0.934608;SB=2;DP4=1,2,1024,952;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P4715L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P323L|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 14900 . GTAT G 66.0 PASS DP=1052;AF=0.003802;SB=0;DP4=524,526,2,2;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||attaat/aat|IN4880N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||attaat/aat|IN488N|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 15157 . C A 355.0 PASS DP=2011;AF=0.011934;SB=834;DP4=1036,716,3,255;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Aaa|Q4965K|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Aaa|Q573K|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15173 . C A 224.0 PASS DP=2059;AF=0.007771;SB=621;DP4=1049,811,1,192;EFF=STOP_GAINED(HIGH|NONSENSE|tCa/tAa|S4970*|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),STOP_GAINED(HIGH|NONSENSE|tCa/tAa|S578*|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15240 . C T 49314.0 PASS DP=1936;AF=0.928719;SB=0;DP4=1,1,922,1004;EFF=SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N4992|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N600|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15672 . GT G 64.0 PASS DP=2535;AF=0.001972;SB=1;DP4=1319,1221,2,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tac/|Y5138|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tac/|Y746|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 17144 . G A 79.0 PASS DP=1360;AF=0.005147;SB=0;DP4=686,665,4,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cGc/cAc|R5627H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cGc/cAc|R303H|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18163 . A G 15785.0 PASS DP=465;AF=0.931183;SB=0;DP4=0,0,231,232;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I5967V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I42V|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18877 . C T 77.0 PASS DP=1379;AF=0.005076;SB=1;DP4=641,723,5,7;EFF=SYNONYMOUS_CODING(LOW|SILENT|Cta/Tta|L6205|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|Cta/Tta|L280|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 19983 . C T 203.0 PASS DP=2894;AF=0.007256;SB=6;DP4=1447,1399,13,20;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtC/gtT|V6573|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|gtC/gtT|V121|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 20091 . C CA 70.0 PASS DP=2054;AF=0.002434;SB=0;DP4=1038,1022,3,2;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||caa/Acaa|Q6611T?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|CA|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||caa/Acaa|Q159T?|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|CA|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 20114 . T A 105.0 PASS DP=1611;AF=0.005587;SB=88;DP4=793,778,0,30;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTc/gAc|V6617D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTc/gAc|V165D|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 20117 . C A 79.0 PASS DP=1586;AF=0.004414;SB=145;DP4=775,740,4,64;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T6618K|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T166K|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 21740 . TCCAATGTTACTTGGTTCCATGCTATACATGTCTCTGGGA T 192.0 PASS DP=1864;AF=0.005901;SB=0;DP4=928,925,6,5;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttacttggttccatgctatacatgtctctgggaccaatggt/ggt|VTWFHAIHVSGTNG62G|1273|S|protein_coding|CODING|GU280_gp02|1|T|INFO_REALIGN_3_PRIME) +NC_045512.2 21762 . C T 49314.0 PASS DP=1599;AF=0.923702;SB=0;DP4=0,1,771,803;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A67V|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21764 . ATACATG A 49314.0 PASS DP=1510;AF=0.990066;SB=0;DP4=8,7,737,758;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||atacatgtc/atc|IHV68I|1273|S|protein_coding|CODING|GU280_gp02|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 21846 . C T 49314.0 PASS DP=1577;AF=0.954344;SB=0;DP4=0,1,764,812;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T95I|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21974 . GATCCATTTT G 66.0 PASS DP=926;AF=0.00432;SB=0;DP4=475,447,2,2;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gatccatttttg/gtg|DPFL138V|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 21986 . GGTGTTTATT G 28101.0 PASS DP=874;AF=0.981693;SB=3;DP4=29,22,436,422;INDEL;HRUN=3;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtgtttattac/gac|GVYY142D|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 22158 . GTTAT G 63.0 PASS DP=1370;AF=0.00292;SB=0;DP4=683,692,2,2;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||tatttt/|YF200|1273|S|protein_coding|CODING|GU280_gp02|1|G|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 22193 . AATT A 27599.0 PASS DP=910;AF=0.934066;SB=45;DP4=143,236,431,419;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattta/ata|NL211I|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22204 . T TGAGCCAGAA 19057.0 PASS DP=778;AF=0.727506;SB=7;DP4=83,109,278,288;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGAAGAt|D215EPED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22204 . T TGAGACAGAA 69.0 PASS DP=778;AF=0.005141;SB=8;DP4=83,109,0,4;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGACAGAAGAt|D215ETED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGACAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22204 . T TGAGCCAGTA 92.0 PASS DP=778;AF=0.007712;SB=21;DP4=83,109,6,0;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGTAGAt|D215EPVD|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGTA|INFO_REALIGN_3_PRIME) +NC_045512.2 22207 . T G 154.0 PASS DP=1321;AF=0.01514;SB=3;DP4=654,640,11,15;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaT/gaG|D215E|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 22218 . GT G 213.0 PASS DP=1342;AF=0.008942;SB=0;DP4=682,683,6,6;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||tcg/|S221|1273|S|protein_coding|CODING|GU280_gp02|1|G|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 22578 . G A 49314.0 PASS DP=1793;AF=0.96319;SB=0;DP4=0,0,901,891;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGt/gAt|G339D|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22673 . T C 33537.0 PASS DP=996;AF=0.906627;SB=11;DP4=3,0,409,584;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tcc/Ccc|S371P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22674 . C T 31816.0 PASS DP=991;AF=0.866801;SB=0;DP4=0,1,402,579;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S371F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22679 . T C 34707.0 PASS DP=1045;AF=0.889952;SB=15;DP4=4,0,431,609;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Cca|S373P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22685 . TC T 110.0 PASS DP=1054;AF=0.005693;SB=0;DP4=435,613,2,4;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||tcc/|S375|1273|S|protein_coding|CODING|GU280_gp02|1|T|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 22686 . C T 37081.0 PASS DP=1054;AF=0.93074;SB=0;DP4=0,0,434,613;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S375F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22992 . G A 13361.0 PASS DP=407;AF=0.911548;SB=0;DP4=1,1,219,186;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGc/aAc|S477N|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22995 . C A 13617.0 PASS DP=411;AF=0.902676;SB=3;DP4=0,1,221,189;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T478K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23013 . A C 20810.0 PASS DP=600;AF=0.916667;SB=0;DP4=2,1,320,276;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gCa|E484A|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23040 . A G 24349.0 PASS DP=725;AF=0.902069;SB=0;DP4=2,1,370,349;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q493R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23048 . G A 30741.0 PASS DP=850;AF=0.955294;SB=0;DP4=0,0,442,408;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G496S|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23055 . A G 27514.0 PASS DP=877;AF=0.851767;SB=0;DP4=0,0,452,417;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q498R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23063 . A T 36959.0 PASS DP=1033;AF=0.957406;SB=0;DP4=0,0,546,487;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aat/Tat|N501Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23075 . T C 34146.0 PASS DP=1050;AF=0.893333;SB=19;DP4=10,1,539,497;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y505H|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23202 . C A 49314.0 PASS DP=1562;AF=0.930218;SB=0;DP4=0,0,763,790;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T547K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23403 . A G 49314.0 PASS DP=3830;AF=0.888512;SB=6;DP4=4,1,1892,1919;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D614G|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23458 . T C 78.0 PASS DP=3959;AF=0.002526;SB=3;DP4=1966,1962,7,11;EFF=SYNONYMOUS_CODING(LOW|SILENT|acT/acC|T632|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23525 . C T 49314.0 PASS DP=3361;AF=0.934543;SB=3;DP4=1,0,1603,1753;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cat/Tat|H655Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23599 . T G 49314.0 PASS DP=1705;AF=0.937243;SB=6;DP4=2,0,765,937;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaG|N679K|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23604 . C A 49314.0 PASS DP=1475;AF=0.947119;SB=0;DP4=0,1,657,812;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cAt|P681H|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23948 . G T 38892.0 PASS DP=1143;AF=0.898513;SB=2;DP4=1,2,599,531;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gat/Tat|D796Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24025 . ACTTT A 61.0 PASS DP=1396;AF=0.002865;SB=0;DP4=699,694,2,2;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||cttttc/|LF822|1273|S|protein_coding|CODING|GU280_gp02|1|A);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 24130 . C A 39806.0 PASS DP=1191;AF=0.889169;SB=11;DP4=0,5,551,625;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaC/aaA|N856K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24424 . A T 49314.0 PASS DP=1687;AF=0.947244;SB=0;DP4=1,2,840,844;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caT|Q954H|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24469 . T A 49314.0 PASS DP=2702;AF=0.941155;SB=0;DP4=2,2,1371,1322;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N969K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24503 . C T 49314.0 PASS DP=2777;AF=0.940223;SB=4;DP4=3,1,1365,1401;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L981F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25000 . C T 28223.0 PASS DP=873;AF=0.907216;SB=9;DP4=0,3,439,430;EFF=SYNONYMOUS_CODING(LOW|SILENT|gaC/gaT|D1146|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25195 . A G 89.0 PASS DP=1810;AF=0.00442;SB=1;DP4=903,891,6,4;EFF=SYNONYMOUS_CODING(LOW|SILENT|aaA/aaG|K1211|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 25584 . C T 49314.0 PASS DP=1783;AF=0.91419;SB=3;DP4=1,0,884,897;EFF=SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T64|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 26270 . C T 49314.0 PASS DP=1942;AF=0.925335;SB=6;DP4=2,0,893,1035;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aTa|T9I|75|E|protein_coding|CODING|GU280_gp04|1|T) +NC_045512.2 26530 . A G 6751.0 PASS DP=211;AF=0.886256;SB=0;DP4=0,0,102,108;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D3G|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26577 . C G 2561.0 PASS DP=72;AF=0.944444;SB=0;DP4=0,0,37,35;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Gaa|Q19E|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26709 . G A 3601.0 PASS DP=105;AF=0.914286;SB=0;DP4=0,0,50,55;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A63T|222|M|protein_coding|CODING|GU280_gp05|1|A) +NC_045512.2 26786 . AGGCTTGATGTGGCTCAGCTACTTCATTGCTTCTT A 105.0 PASS DP=125;AF=0.032;SB=0;DP4=58,63,2,2;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggcttgatgtggctcagctacttcattgcttctttc/|GLMWLSYFIASF89|222|M|protein_coding|CODING|GU280_gp05|1|A);LOF=(M|GU280_gp05|1|1.00) +NC_045512.2 27133 . ATAAATT A 65.0 PASS DP=5;AF=0.4;SB=0;DP4=1,2,1,1;INDEL;HRUN=1;EFF=STOP_GAINED+CODON_CHANGE_PLUS_CODON_DELETION(HIGH||tataaatta/taa|YKL204*|222|M|protein_coding|CODING|GU280_gp05|1|A) +NC_045512.2 27259 . A C 49314.0 PASS DP=1633;AF=0.914881;SB=6;DP4=0,2,863,764;EFF=SYNONYMOUS_CODING(LOW|SILENT|Agg/Cgg|R20|61|ORF6|protein_coding|CODING|GU280_gp06|1|C) +NC_045512.2 27384 . T C 96.0 PASS DP=2252;AF=0.00444;SB=0;DP4=1116,1121,5,5;EFF=SYNONYMOUS_CODING(LOW|SILENT|gaT/gaC|D61|61|ORF6|protein_coding|CODING|GU280_gp06|1|C) +NC_045512.2 27481 . C T 79.0 PASS DP=2285;AF=0.003501;SB=1;DP4=1117,1155,5,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L30F|121|ORF7a|protein_coding|CODING|GU280_gp07|1|T) +NC_045512.2 27512 . A G 127.0 PASS DP=2297;AF=0.005224;SB=13;DP4=1140,1126,5,14;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tAc/tGc|Y40C|121|ORF7a|protein_coding|CODING|GU280_gp07|1|G) +NC_045512.2 27578 . AATT A 65.0 PASS DP=1221;AF=0.003276;SB=0;DP4=635,582,2,2;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||caattt/cat|QF62H|121|ORF7a|protein_coding|CODING|GU280_gp07|1|A) +NC_045512.2 27686 . C T 1642.0 PASS DP=1382;AF=0.055716;SB=0;DP4=645,643,44,47;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCt/tTt|S98F|121|ORF7a|protein_coding|CODING|GU280_gp07|1|T) +NC_045512.2 27807 . C T 49314.0 PASS DP=1836;AF=0.944444;SB=0;DP4=1,1,877,948;EFF=SYNONYMOUS_CODING(LOW|SILENT|Cta/Tta|L18|43|ORF7b|protein_coding|CODING|GU280_gp08|1|T) +NC_045512.2 28271 . A T 49314.0 PASS DP=2635;AF=0.936622;SB=0;DP4=1,2,1289,1333 +NC_045512.2 28311 . C T 49314.0 PASS DP=2632;AF=0.841945;SB=14;DP4=2,10,1258,1344;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cTc|P13L|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28361 . GGAGAACGCA G 49314.0 PASS DP=2240;AF=0.805804;SB=1;DP4=211,232,847,958;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggagaacgcagt/ggt|GERS30G|419|N|protein_coding|CODING|GU280_gp10|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 28363 . AGAACGCAGT A 168.0 PASS DP=1853;AF=0.008635;SB=20;DP4=868,972,13,3;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gaacgcagtggg/ggg|ERSG31G|419|N|protein_coding|CODING|GU280_gp10|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 28881 . G A 43800.0 PASS DP=1232;AF=0.936688;SB=3;DP4=0,1,630,599;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGg/aAg|R203K|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28882 . G A 41939.0 PASS DP=1230;AF=0.917886;SB=3;DP4=0,1,628,595;EFF=SYNONYMOUS_CODING(LOW|SILENT|agG/agA|R203|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28883 . G C 43631.0 PASS DP=1232;AF=0.948052;SB=0;DP4=0,0,629,601;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gga/Cga|G204R|419|N|protein_coding|CODING|GU280_gp10|1|C) +NC_045512.2 28987 . CCAA C 88.0 PASS DP=1025;AF=0.004878;SB=0;DP4=519,519,2,3;INDEL;HRUN=2;EFF=CODON_DELETION(MODERATE||caa/|Q242|419|N|protein_coding|CODING|GU280_gp10|1|C|INFO_REALIGN_3_PRIME) +NC_045512.2 29311 . CA C 61.0 PASS DP=1548;AF=0.002584;SB=0;DP4=779,765,2,2;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||aaa/|K347|419|N|protein_coding|CODING|GU280_gp10|1|C|INFO_REALIGN_3_PRIME);LOF=(N|GU280_gp10|1|1.00) +NC_045512.2 29355 . A T 137.0 PASS DP=1688;AF=0.006517;SB=1;DP4=840,828,6,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAa/aTa|K361I|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 29555 . C T 80.0 PASS DP=1239;AF=0.00565;SB=1;DP4=638,591,4,5 +NC_045512.2 29574 . TTTTCGC T 144.0 PASS DP=1250;AF=0.0064;SB=0;DP4=643,599,4,4;INDEL;HRUN=4;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttcgctttt/ttt|FAF7F|38|ORF10|protein_coding|CODING|GU280_gp11|1|T|INFO_REALIGN_3_PRIME) +NC_045512.2 29580 . CT C 61.0 PASS DP=1252;AF=0.003195;SB=0;DP4=647,605,2,2;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttt/|F9|38|ORF10|protein_coding|CODING|GU280_gp11|1|C|INFO_REALIGN_3_PRIME);LOF=(ORF10|GU280_gp11|1|1.00) diff --git a/example_data/example_mave_data/input/sample-07.vcf b/example_data/example_mave_data/input/sample-07.vcf new file mode 100644 index 0000000..7c31acd --- /dev/null +++ b/example_data/example_mave_data/input/sample-07.vcf @@ -0,0 +1,136 @@ +##fileformat=VCFv4.0 +##FILTER= +##fileDate=20240114 +##source=lofreq call --verbose --ref reference.fa --call-indels --min-cov 5 --max-depth 1000000 --min-bq 30 --min-alt-bq 30 --min-mq 20 --max-mq 255 --min-jq 0 --min-alt-jq 0 --def-alt-jq 0 --sig 0.0005 --bonf dynamic --no-default-filter --no-default-filter -r NC_045512.2:1-7475 -o /data/jwd02f/main/066/348/66348162/tmp/lofreq2_call_parallel78jkk747/0.vcf.gz reads.bam +##reference=reference.fa +##INFO= +##INFO= --min-bq among all bases at the site"> +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##INFO= +##bcftools_annotateVersion=1.10.2+htslib-1.10.2 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites -AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 21:37:04 2024 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites +AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 21:37:50 2024 +##SnpEffVersion="4.5covid19 (build 2020-04-15 22:26), by Pablo Cingolani" +##SnpEffCmd="SnpEff -i vcf -o vcf -formatEff -classic -no-downstream -no-intergenic -no-upstream -stats /data/jwd05e/main/066/348/66348342/outputs/dataset_e4626423-1aa5-4f44-8512-7fa4819dae1e.dat NC_045512.2 /data/dnb09/galaxy_db/files/d/5/2/dataset_d52f9a88-3f77-488a-b6b2-d7e595058705.dat " +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +NC_045512.2 241 . C T 22488.0 PASS DP=695;AF=0.886331;SB=0;DP4=0,0,342,352 +NC_045512.2 509 . GGTCATGTTATGGTT G 145.0 PASS DP=4068;AF=0.002704;SB=0;DP4=2009,2042,5,6;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 509 . GGTCATGTT G 75.0 PASS DP=4068;AF=0.001475;SB=0;DP4=2009,2042,3,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||ggtcatgtt/|GHV82|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 1026 . C CT 426.0 PASS DP=1827;AF=0.012042;SB=0;DP4=961,844,12,10;INDEL;HRUN=4;EFF=FRAME_SHIFT+STOP_GAINED(HIGH||gaa/Tgaa|E256*?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT+STOP_GAINED(HIGH||gaa/Tgaa|E256*?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT+STOP_GAINED(HIGH||gaa/Tgaa|E76*?|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT+STOP_GAINED(HIGH||gaa/Tgaa|E76*?|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14);NMD=(ORF1ab|GU280_gp01|28|0.04) +NC_045512.2 1628 . C CA 66.0 PASS DP=1901;AF=0.00263;SB=0;DP4=1019,877,3,2;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||gag/Agag|E457R?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|CA|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gag/Agag|E457R?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|CA|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gag/Agag|E277R?|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|CA|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gag/Agag|E277R?|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|CA|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 2248 . T G 92.0 PASS DP=1328;AF=0.006024;SB=273;DP4=577,651,88,0;EFF=SYNONYMOUS_CODING(LOW|SILENT|ggT/ggG|G661|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|ggT/ggG|G661|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|ggT/ggG|G481|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ggT/ggG|G481|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2330 . T A 218.0 PASS DP=1723;AF=0.009286;SB=2;DP4=780,868,12,10;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2832 . A G 32215.0 PASS DP=1033;AF=0.856728;SB=0;DP4=0,1,468,559;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2952 . AT A 69.0 PASS DP=800;AF=0.005;SB=0;DP4=379,423,2,2;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||tta/|L897|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L897|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L79|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L79|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 3037 . C T 30661.0 PASS DP=958;AF=0.859081;SB=0;DP4=0,0,454,492;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3862 . T A 111.0 PASS DP=84;AF=0.059524;SB=0;DP4=39,39,3,3;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V1199|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V1199|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V381|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V381|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5386 . T G 49314.0 PASS DP=2607;AF=0.807825;SB=13;DP4=4,13,1277,1290;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5743 . G C 214.0 PASS DP=1631;AF=0.010423;SB=1;DP4=803,794,11,13;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5744 . T C 261.0 PASS DP=1631;AF=0.012262;SB=4;DP4=795,797,18,12;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6510 . ATAG A 109.0 PASS DP=1214;AF=0.00659;SB=7;DP4=635,570,2,6;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||agt/|S2083|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||agt/|S2083|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||agt/|S1265|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||agt/|S1265|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 6512 . AGTT A 40895.0 PASS DP=1213;AF=0.988458;SB=3;DP4=6,9,631,568;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6696 . C CT 688.0 PASS DP=1748;AF=0.018879;SB=0;DP4=866,880,17,16;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ctt/Tctt|L2146S?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L2146S?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L1328S?|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L1328S?|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 6961 . G GT 72.0 PASS DP=1341;AF=0.003729;SB=1;DP4=657,682,3,2;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||tta/ttTa|L2234F?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|GT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/ttTa|L2234F?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|GT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/ttTa|L1416F?|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|GT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/ttTa|L1416F?|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|GT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 8376 . CA C 83.0 PASS DP=1706;AF=0.003517;SB=0;DP4=936,764,3,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||agt/|S2706|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||agt/|S2706|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||agt/|S1888|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||agt/|S1888|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 8393 . G A 49314.0 PASS DP=1974;AF=0.890577;SB=0;DP4=5,4,1078,879;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 9078 . T C 49314.0 PASS DP=2034;AF=0.807768;SB=14;DP4=7,1,971,1026;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTa/gCa|V2938A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTa/gCa|V2938A|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTa/gCa|V175A|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTa/gCa|V175A|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 9541 . CTGTTTAACACCAGTTTACTCATTCTTACCTGG C 73.0 PASS DP=2166;AF=0.002308;SB=0;DP4=1170,991,3,2;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||acaccagtttactcattcttacctggtgtttat/|TPVYSFLPGVY3095|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acaccagtttactcattcttacctggtgtttat/|TPVYSFLPGVY3095|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acaccagtttactcattcttacctggtgtttat/|TPVYSFLPGVY332|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acaccagtttactcattcttacctggtgtttat/|TPVYSFLPGVY332|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 10029 . C T 45418.0 PASS DP=1524;AF=0.813648;SB=2;DP4=4,6,750,740;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10148 . C T 105.0 PASS DP=2224;AF=0.004496;SB=12;DP4=1118,1067,19,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L3295F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L3295F|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L32F|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L32F|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10326 . T G 113.0 PASS DP=2619;AF=0.0042;SB=343;DP4=1135,1332,124,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTt/gGt|V3354G|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTt/gGt|V3354G|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTt/gGt|V91G|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTt/gGt|V91G|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10449 . C A 49314.0 PASS DP=2050;AF=0.836098;SB=24;DP4=3,18,955,1057;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10484 . T G 300.0 PASS DP=865;AF=0.020809;SB=6;DP4=440,395,9,14;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10541 . C A 252.0 PASS DP=1008;AF=0.015873;SB=2;DP4=492,482,11,14;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10763 . T G 82.0 PASS DP=1959;AF=0.004084;SB=86;DP4=943,959,37,2;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Gac|Y3500D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Gac|Y3500D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Gac|Y237D|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Gac|Y237D|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11095 . C CT 253.0 PASS DP=1184;AF=0.011824;SB=0;DP4=611,559,7,7;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||tta/ttTa|L3612F?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/ttTa|L3612F?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/ttTa|L43F?|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/ttTa|L43F?|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11279 . ACTAGTTTGT A 67.0 PASS DP=1577;AF=0.005707;SB=10;DP4=728,844,7,2;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||agtttgtct/|SLS3673|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||agtttgtct/|SLS3673|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||agtttgtct/|SLS104|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_DELETION(MODERATE||agtttgtct/|SLS104|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 11282 . AGTTTGTCTG A 49314.0 PASS DP=1538;AF=0.894668;SB=19;DP4=91,72,621,755;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 11287 . GTCTGGTTTT G 64.0 PASS DP=1413;AF=0.004246;SB=20;DP4=642,768,6,0;INDEL;HRUN=1;EFF=CODON_DELETION(MODERATE||tctggtttt/|SGF3675|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),CODON_DELETION(MODERATE||tctggtttt/|SGF3675|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),CODON_DELETION(MODERATE||tctggtttt/|SGF106|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),CODON_DELETION(MODERATE||tctggtttt/|SGF106|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11537 . A G 49314.0 PASS DP=3607;AF=0.821181;SB=2;DP4=6,4,1742,1831;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11613 . A T 94.0 PASS DP=2508;AF=0.004386;SB=319;DP4=1038,1328,119,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tAt/tTt|Y3783F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tAt/tTt|Y3783F|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tAt/tTt|Y214F|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tAt/tTt|Y214F|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13142 . AATTGTG A 62.0 PASS DP=1505;AF=0.002658;SB=0;DP4=688,814,2,2;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattgtgtt/att|NCV4293I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattgtgtt/att|NCV4293I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattgtgtt/att|NCV40I|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattgtgtt/att|NCV40I|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13195 . T C 49314.0 PASS DP=3608;AF=0.857539;SB=21;DP4=11,1,1915,1662;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13442 . T G 96.0 PASS DP=3054;AF=0.003274;SB=315;DP4=1196,1682,144,21;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S4393A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S4393A|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S1A|12|ORF1ab|protein_coding|CODING|YP_009725312.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S1A|931|ORF1ab|protein_coding|CODING|YP_009725307.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 14408 . C T 49314.0 PASS DP=1942;AF=0.883625;SB=3;DP4=0,1,982,950;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P4715L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P323L|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 14866 . G GT 70.0 PASS DP=809;AF=0.004944;SB=0;DP4=401,408,2,2;INDEL;HRUN=2;EFF=FRAME_SHIFT+STOP_GAINED(HIGH||gat/Tgat|D4869*?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|GT|INFO_REALIGN_3_PRIME),FRAME_SHIFT+STOP_GAINED(HIGH||gat/Tgat|D477*?|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|GT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 15157 . C A 335.0 PASS DP=1959;AF=0.011741;SB=679;DP4=1048,715,1,194;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Aaa|Q4965K|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Aaa|Q573K|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15173 . C A 119.0 PASS DP=2033;AF=0.004919;SB=517;DP4=1063,810,0,151;EFF=STOP_GAINED(HIGH|NONSENSE|tCa/tAa|S4970*|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),STOP_GAINED(HIGH|NONSENSE|tCa/tAa|S578*|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15240 . C T 49314.0 PASS DP=1866;AF=0.88746;SB=0;DP4=0,0,878,976;EFF=SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N4992|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N600|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15781 . A T 124.0 PASS DP=2895;AF=0.004145;SB=223;DP4=1325,1461,85,3;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aac/Tac|N5173Y|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aac/Tac|N781Y|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 16251 . T G 124.0 PASS DP=2841;AF=0.004224;SB=377;DP4=1284,1431,120,0;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tgT/tgG|C5329W|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tgT/tgG|C5W|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 16457 . C T 121.0 PASS DP=2109;AF=0.005216;SB=17;DP4=991,1087,19,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCa/tTa|S5398L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCa/tTa|S74L|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 16501 . G GT 61.0 PASS DP=935;AF=0.004278;SB=0;DP4=479,452,2,2;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||ggt/Tggt|G5415W?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|GT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggt/Tggt|G91W?|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|GT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 16837 . GA G 84.0 PASS DP=3165;AF=0.002212;SB=0;DP4=1659,1499,4,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aaa/|K5526|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K202|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 17502 . C T 1416.0 PASS DP=2614;AF=0.029457;SB=1;DP4=1259,1257,50,45;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F5746|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F422|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18163 . A G 13018.0 PASS DP=437;AF=0.82151;SB=0;DP4=1,0,218,216;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I5967V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I42V|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 19983 . C T 92.0 PASS DP=2801;AF=0.00357;SB=13;DP4=1408,1339,8,18;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtC/gtT|V6573|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|gtC/gtT|V121|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 21740 . TCCAATGTTACTTGGTTCCATGCTATACATGTCTCTGGGA T 196.0 PASS DP=1825;AF=0.006027;SB=4;DP4=903,911,7,4;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttacttggttccatgctatacatgtctctgggaccaatggt/ggt|VTWFHAIHVSGTNG62G|1273|S|protein_coding|CODING|GU280_gp02|1|T|INFO_REALIGN_3_PRIME) +NC_045512.2 21762 . C T 45113.0 PASS DP=1506;AF=0.87915;SB=0;DP4=2,2,706,769;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A67V|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21764 . ATACATG A 46688.0 PASS DP=1423;AF=0.983837;SB=5;DP4=15,10,672,728;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||atacatgtc/atc|IHV68I|1273|S|protein_coding|CODING|GU280_gp02|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 21846 . C T 48800.0 PASS DP=1406;AF=0.921764;SB=6;DP4=0,3,666,729;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T95I|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21985 . GGGTGTTTAT G 156.0 PASS DP=750;AF=0.013333;SB=9;DP4=371,373,8,2;INDEL;HRUN=3;EFF=CODON_DELETION(MODERATE||ggtgtttat/|GVY142|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 21986 . GGTGTTTATT G 21812.0 PASS DP=729;AF=0.964335;SB=4;DP4=27,20,348,355;INDEL;HRUN=3;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtgtttattac/gac|GVYY142D|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 22193 . AATT A 21016.0 PASS DP=727;AF=0.918845;SB=62;DP4=98,194,342,326;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattta/ata|NL211I|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22204 . T TGAGCCAGAA 12438.0 PASS DP=597;AF=0.638191;SB=6;DP4=83,103,192,189;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGAAGAt|D215EPED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22204 . T TGAGCCAGTA 70.0 PASS DP=597;AF=0.0067;SB=13;DP4=83,103,4,0;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGTAGAt|D215EPVD|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGTA|INFO_REALIGN_3_PRIME) +NC_045512.2 22204 . T TGAGACAGAA 80.0 PASS DP=597;AF=0.008375;SB=11;DP4=83,103,0,5;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGACAGAAGAt|D215ETED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGACAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22578 . G A 49314.0 PASS DP=1514;AF=0.937913;SB=0;DP4=0,0,762,748;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGt/gAt|G339D|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22673 . T C 22762.0 PASS DP=746;AF=0.83244;SB=0;DP4=2,2,309,427;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tcc/Ccc|S371P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22674 . C T 21500.0 PASS DP=743;AF=0.79004;SB=0;DP4=0,1,307,417;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S371F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22679 . T C 23838.0 PASS DP=783;AF=0.8212;SB=7;DP4=4,1,328,441;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Cca|S373P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22686 . C T 25311.0 PASS DP=792;AF=0.853535;SB=1;DP4=1,3,331,452;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S375F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22992 . G A 12027.0 PASS DP=387;AF=0.865633;SB=0;DP4=0,0,211,174;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGc/aAc|S477N|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22995 . C A 12825.0 PASS DP=398;AF=0.88191;SB=3;DP4=2,4,215,177;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T478K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23013 . A C 18316.0 PASS DP=550;AF=0.883636;SB=1;DP4=2,3,296,249;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gCa|E484A|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23040 . A G 20062.0 PASS DP=629;AF=0.860095;SB=0;DP4=0,0,325,299;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q493R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23048 . G A 25705.0 PASS DP=729;AF=0.930041;SB=0;DP4=1,0,376,351;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G496S|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23055 . A G 22128.0 PASS DP=753;AF=0.806109;SB=0;DP4=0,0,382,362;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q498R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23063 . A T 31095.0 PASS DP=899;AF=0.931035;SB=0;DP4=0,0,471,427;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aat/Tat|N501Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23075 . T C 26190.0 PASS DP=894;AF=0.815436;SB=13;DP4=8,1,462,417;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y505H|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23202 . C A 44604.0 PASS DP=1360;AF=0.873529;SB=4;DP4=3,1,659,685;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T547K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23403 . A G 49314.0 PASS DP=3542;AF=0.806889;SB=14;DP4=14,5,1725,1762;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D614G|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23501 . G T 49314.0 PASS DP=3367;AF=0.810514;SB=6;DP4=9,16,1603,1712;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gca/Tca|A647S|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23525 . C T 49314.0 PASS DP=2954;AF=0.883886;SB=3;DP4=5,3,1391,1545;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cat/Tat|H655Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23599 . T G 49314.0 PASS DP=1584;AF=0.885732;SB=3;DP4=4,2,698,874;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaG|N679K|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23604 . C A 45331.0 PASS DP=1354;AF=0.905465;SB=5;DP4=0,3,591,755;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cAt|P681H|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23948 . G T 37979.0 PASS DP=1220;AF=0.82623;SB=0;DP4=3,3,647,541;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gat/Tat|D796Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24130 . C A 43955.0 PASS DP=1461;AF=0.80835;SB=3;DP4=6,11,656,777;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaC/aaA|N856K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24424 . A T 44036.0 PASS DP=1376;AF=0.869913;SB=0;DP4=4,4,684,682;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caT|Q954H|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24469 . T A 49314.0 PASS DP=2552;AF=0.892633;SB=0;DP4=6,6,1306,1232;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N969K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24503 . C T 49314.0 PASS DP=2676;AF=0.886771;SB=1;DP4=3,2,1315,1341;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L981F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24858 . G A 160.0 PASS DP=1119;AF=0.010724;SB=15;DP4=563,524,6,16;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGc/gAc|G1099D|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 25000 . C T 22907.0 PASS DP=794;AF=0.806045;SB=10;DP4=3,10,389,382;EFF=SYNONYMOUS_CODING(LOW|SILENT|gaC/gaT|D1146|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25584 . C T 47011.0 PASS DP=1495;AF=0.854181;SB=0;DP4=1,2,722,759;EFF=SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T64|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 26270 . C T 49314.0 PASS DP=1730;AF=0.858382;SB=1;DP4=2,4,800,912;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aTa|T9I|75|E|protein_coding|CODING|GU280_gp04|1|T) +NC_045512.2 26530 . A G 22206.0 PASS DP=735;AF=0.834014;SB=0;DP4=0,0,343,381;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D3G|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26574 . GAAC G 82.0 PASS DP=441;AF=0.00907;SB=0;DP4=214,225,2,2;INDEL;HRUN=2;EFF=CODON_DELETION(MODERATE||caa/|Q19|222|M|protein_coding|CODING|GU280_gp05|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 26577 . C G 7860.0 PASS DP=261;AF=0.83908;SB=0;DP4=4,4,121,129;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Gaa|Q19E|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26654 . G GT 67.0 PASS DP=197;AF=0.020305;SB=0;DP4=95,98,2,2;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||ttg/ttTg|L46F?|222|M|protein_coding|CODING|GU280_gp05|1|GT|INFO_REALIGN_3_PRIME);LOF=(M|GU280_gp05|1|1.00) +NC_045512.2 26709 . G A 8623.0 PASS DP=289;AF=0.806228;SB=0;DP4=0,0,141,144;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A63T|222|M|protein_coding|CODING|GU280_gp05|1|A) +NC_045512.2 27259 . A C 41901.0 PASS DP=1356;AF=0.84292;SB=0;DP4=1,0,714,632;EFF=SYNONYMOUS_CODING(LOW|SILENT|Agg/Cgg|R20|61|ORF6|protein_coding|CODING|GU280_gp06|1|C) +NC_045512.2 27373 . A ACTTTCGATCTCT 65.0 PASS DP=2067;AF=0.002903;SB=0;DP4=1030,1032,3,3;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||atg/aCTTTCGATCTCTtg|M58TFDLL|61|ORF6|protein_coding|CODING|GU280_gp06|1|ACTTTCGATCTCT) +NC_045512.2 27637 . G GT 63.0 PASS DP=1363;AF=0.002935;SB=0;DP4=682,677,2,2;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||tca/tTca|S83F?|121|ORF7a|protein_coding|CODING|GU280_gp07|1|GT|INFO_REALIGN_3_PRIME);LOF=(ORF7a|GU280_gp07|1|1.00) +NC_045512.2 27807 . C T 49314.0 PASS DP=1765;AF=0.887819;SB=0;DP4=1,1,839,916;EFF=SYNONYMOUS_CODING(LOW|SILENT|Cta/Tta|L18|43|ORF7b|protein_coding|CODING|GU280_gp08|1|T) +NC_045512.2 28254 . A C 96.0 PASS DP=2153;AF=0.004645;SB=11;DP4=1049,1070,6,15;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Atc/Ctc|I121L|121|ORF8|protein_coding|CODING|GU280_gp09|1|C) +NC_045512.2 28271 . A T 49314.0 PASS DP=2451;AF=0.880865;SB=2;DP4=2,1,1180,1258 +NC_045512.2 28311 . C T 49314.0 PASS DP=2470;AF=0.780972;SB=15;DP4=3,14,1130,1293;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cTc|P13L|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28361 . GGAGAACGCA G 49314.0 PASS DP=2093;AF=0.777353;SB=1;DP4=219,256,738,889;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggagaacgcagt/ggt|GERS30G|419|N|protein_coding|CODING|GU280_gp10|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 28363 . AGAACGCAGT A 514.0 PASS DP=1691;AF=0.020698;SB=75;DP4=759,906,32,3;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gaacgcagtggg/ggg|ERSG31G|419|N|protein_coding|CODING|GU280_gp10|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 28881 . G A 43468.0 PASS DP=1275;AF=0.905098;SB=4;DP4=1,4,634,633;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGg/aAg|R203K|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28882 . G A 40913.0 PASS DP=1274;AF=0.869702;SB=18;DP4=0,6,634,622;EFF=SYNONYMOUS_CODING(LOW|SILENT|agG/agA|R203|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28883 . G C 43420.0 PASS DP=1279;AF=0.915559;SB=0;DP4=0,0,637,640;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gga/Cga|G204R|419|N|protein_coding|CODING|GU280_gp10|1|C) +NC_045512.2 29377 . TA T 79.0 PASS DP=2170;AF=0.002765;SB=0;DP4=1087,1082,3,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aag/|K370|419|N|protein_coding|CODING|GU280_gp10|1|T|INFO_REALIGN_3_PRIME);LOF=(N|GU280_gp10|1|1.00) +NC_045512.2 29562 . G A 102.0 PASS DP=1093;AF=0.007319;SB=0;DP4=555,514,7,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGc/gAc|G2D|38|ORF10|protein_coding|CODING|GU280_gp11|1|A) +NC_045512.2 29750 . C T 38295.0 PASS DP=1281;AF=0.824356;SB=0;DP4=0,0,593,669 diff --git a/example_data/example_mave_data/input/sample-08.vcf b/example_data/example_mave_data/input/sample-08.vcf new file mode 100644 index 0000000..cd7933f --- /dev/null +++ b/example_data/example_mave_data/input/sample-08.vcf @@ -0,0 +1,89 @@ +##fileformat=VCFv4.0 +##FILTER= +##fileDate=20240114 +##source=lofreq call --verbose --ref reference.fa --call-indels --min-cov 5 --max-depth 1000000 --min-bq 30 --min-alt-bq 30 --min-mq 20 --max-mq 255 --min-jq 0 --min-alt-jq 0 --def-alt-jq 0 --sig 0.0005 --bonf dynamic --no-default-filter --no-default-filter -r NC_045512.2:1-7475 -o /data/jwd02f/main/066/348/66348163/tmp/lofreq2_call_parallelrrrw0nqf/0.vcf.gz reads.bam +##reference=reference.fa +##INFO= +##INFO= --min-bq among all bases at the site"> +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##INFO= +##bcftools_annotateVersion=1.10.2+htslib-1.10.2 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites -AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 21:58:19 2024 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites +AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 21:59:29 2024 +##SnpEffVersion="4.5covid19 (build 2020-04-15 22:26), by Pablo Cingolani" +##SnpEffCmd="SnpEff -i vcf -o vcf -formatEff -classic -no-downstream -no-intergenic -no-upstream -stats /data/jwd02f/main/066/348/66348343/outputs/dataset_70ba37f7-e7b2-499a-9e08-2aa221dd6c6f.dat NC_045512.2 /data/dnb09/galaxy_db/files/1/8/8/dataset_18889acb-965d-45b5-a945-557fd1ec5889.dat " +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +NC_045512.2 2832 . A G 16302.0 PASS DP=468;AF=0.938034;SB=0;DP4=0,1,215,251;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 4786 . T C 81.0 PASS DP=4423;AF=0.002261;SB=2;DP4=2206,2198,5,7;EFF=SYNONYMOUS_CODING(LOW|SILENT|ctT/ctC|L1507|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|ctT/ctC|L1507|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|ctT/ctC|L689|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ctT/ctC|L689|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5386 . T G 32232.0 PASS DP=960;AF=0.90625;SB=4;DP4=1,3,479,476;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5743 . G C 107.0 PASS DP=1848;AF=0.005411;SB=0;DP4=919,918,5,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5744 . T C 150.0 PASS DP=1846;AF=0.007042;SB=3;DP4=911,915,10,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5924 . G A 35660.0 PASS DP=1094;AF=0.907678;SB=0;DP4=1,1,542,548;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtt/Att|V1887I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtt/Att|V1887I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtt/Att|V1069I|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtt/Att|V1069I|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6512 . AGTT A 462.0 PASS DP=13;AF=1;SB=0;DP4=0,0,7,6;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 8393 . G A 2955.0 PASS DP=88;AF=0.920455;SB=0;DP4=0,0,45,43;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10029 . C T 5734.0 PASS DP=184;AF=0.875;SB=0;DP4=0,0,92,91;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10449 . C A 2813.0 PASS DP=96;AF=0.864583;SB=0;DP4=0,0,50,46;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10484 . T G 346.0 PASS DP=64;AF=0.203125;SB=8;DP4=30,20,5,9;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10541 . C A 135.0 PASS DP=94;AF=0.06383;SB=0;DP4=46,42,3,3;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11282 . AGTTTGTCTG A 8666.0 PASS DP=252;AF=0.912698;SB=7;DP4=7,15,112,118;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 11537 . A G 40888.0 PASS DP=1199;AF=0.924103;SB=2;DP4=2,1,595,600;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11920 . TA T 58.0 PASS DP=36;AF=0.055556;SB=0;DP4=17,17,1,1;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||aaa/|K3886|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K3886|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K27|82|ORF1ab|protein_coding|CODING|YP_009725303.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K27|82|ORF1ab|protein_coding|CODING|YP_009742614.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 13195 . T C 17123.0 PASS DP=531;AF=0.896422;SB=0;DP4=0,0,241,287;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 14408 . C T 17844.0 PASS DP=509;AF=0.948919;SB=0;DP4=0,0,254,255;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P4715L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P323L|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15240 . C T 28904.0 PASS DP=831;AF=0.925391;SB=0;DP4=0,0,401,428;EFF=SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N4992|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N600|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 17561 . G A 7777.0 PASS DP=3342;AF=0.103232;SB=0;DP4=1484,1483,184,185;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cGg/cAg|R5766Q|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cGg/cAg|R442Q|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18966 . T C 6101.0 PASS DP=956;AF=0.232218;SB=0;DP4=363,338,130,117;EFF=SYNONYMOUS_CODING(LOW|SILENT|tgT/tgC|C6234|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),SYNONYMOUS_CODING(LOW|SILENT|tgT/tgC|C309|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 21762 . C T 49314.0 PASS DP=1712;AF=0.96028;SB=0;DP4=0,1,852,854;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A67V|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21764 . ATACATG A 49314.0 PASS DP=1616;AF=0.996287;SB=1;DP4=2,4,805,805;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||atacatgtc/atc|IHV68I|1273|S|protein_coding|CODING|GU280_gp02|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 21846 . C T 49314.0 PASS DP=1443;AF=0.957034;SB=0;DP4=0,0,703,736;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T95I|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21986 . GGTGTTTATT G 1449.0 PASS DP=46;AF=0.956522;SB=7;DP4=0,2,26,18;INDEL;HRUN=3;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtgtttattac/gac|GVYY142D|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 22193 . AATT A 2841.0 PASS DP=85;AF=0.976471;SB=6;DP4=3,8,41,42;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattta/ata|NL211I|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22204 . T TGAGCCAGAA 2355.0 PASS DP=77;AF=0.844156;SB=1;DP4=6,8,31,34;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGAAGAt|D215EPED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22297 . T C 361.0 PASS DP=106;AF=0.132075;SB=0;DP4=45,44,8,9;EFF=SYNONYMOUS_CODING(LOW|SILENT|caT/caC|H245|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22992 . G A 635.0 PASS DP=20;AF=0.9;SB=0;DP4=1,0,10,9;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGc/aAc|S477N|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22995 . C A 725.0 PASS DP=21;AF=0.952381;SB=0;DP4=0,0,11,10;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T478K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23013 . A C 1014.0 PASS DP=29;AF=0.931035;SB=0;DP4=1,0,14,14;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gCa|E484A|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23040 . A G 1461.0 PASS DP=42;AF=0.952381;SB=0;DP4=0,0,22,20;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q493R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23048 . G A 1758.0 PASS DP=46;AF=1;SB=0;DP4=0,0,24,22;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G496S|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23055 . A G 1694.0 PASS DP=50;AF=0.92;SB=0;DP4=0,0,26,24;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q498R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23063 . A T 1862.0 PASS DP=54;AF=0.944444;SB=0;DP4=0,0,28,26;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aat/Tat|N501Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23075 . T C 1828.0 PASS DP=50;AF=0.98;SB=0;DP4=0,0,26,24;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y505H|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23202 . C A 1972.0 PASS DP=56;AF=0.928571;SB=0;DP4=0,0,27,28;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T547K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23948 . G T 1073.0 PASS DP=32;AF=0.90625;SB=0;DP4=1,1,16,14;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gat/Tat|D796Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24130 . C A 1498.0 PASS DP=45;AF=0.911111;SB=0;DP4=0,1,21,23;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaC/aaA|N856K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24424 . A T 5012.0 PASS DP=142;AF=0.950704;SB=0;DP4=0,0,71,71;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caT|Q954H|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24469 . T A 49314.0 PASS DP=2281;AF=0.928979;SB=11;DP4=7,1,1199,1071;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N969K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24503 . C T 49314.0 PASS DP=2956;AF=0.936062;SB=0;DP4=2,1,1508,1437;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L981F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25000 . C T 306.0 PASS DP=8;AF=1;SB=0;DP4=0,0,4,4;EFF=SYNONYMOUS_CODING(LOW|SILENT|gaC/gaT|D1146|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25584 . C T 15306.0 PASS DP=448;AF=0.912946;SB=0;DP4=0,0,222,223;EFF=SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T64|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 26248 . T C 4067.0 PASS DP=2716;AF=0.07106;SB=1;DP4=1203,1298,97,110;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y2H|75|E|protein_coding|CODING|GU280_gp04|1|C) +NC_045512.2 26270 . C T 49314.0 PASS DP=2176;AF=0.923713;SB=2;DP4=0,2,1015,1154;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aTa|T9I|75|E|protein_coding|CODING|GU280_gp04|1|T) +NC_045512.2 26530 . A G 3232.0 PASS DP=92;AF=0.945652;SB=0;DP4=0,0,45,47;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D3G|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26577 . C G 1765.0 PASS DP=48;AF=0.958333;SB=0;DP4=0,0,24,24;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Gaa|Q19E|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26709 . G A 3564.0 PASS DP=106;AF=0.924528;SB=0;DP4=0,0,53,53;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A63T|222|M|protein_coding|CODING|GU280_gp05|1|A) +NC_045512.2 27259 . A C 10290.0 PASS DP=295;AF=0.945763;SB=0;DP4=0,0,150,144;EFF=SYNONYMOUS_CODING(LOW|SILENT|Agg/Cgg|R20|61|ORF6|protein_coding|CODING|GU280_gp06|1|C) +NC_045512.2 27807 . C T 49314.0 PASS DP=3675;AF=0.948299;SB=0;DP4=1,0,1865,1801;EFF=SYNONYMOUS_CODING(LOW|SILENT|Cta/Tta|L18|43|ORF7b|protein_coding|CODING|GU280_gp08|1|T) +NC_045512.2 28254 . A C 111.0 PASS DP=5408;AF=0.002774;SB=1;DP4=2701,2671,9,11;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Atc/Ctc|I121L|121|ORF8|protein_coding|CODING|GU280_gp09|1|C) +NC_045512.2 28271 . A T 49314.0 PASS DP=6657;AF=0.949677;SB=14;DP4=1,7,3326,3309 +NC_045512.2 28292 . CA C 141.0 PASS DP=6848;AF=0.001752;SB=1;DP4=3360,3477,5,7;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||aat/|N8|419|N|protein_coding|CODING|GU280_gp10|1|C|INFO_REALIGN_3_PRIME) +NC_045512.2 28293 . A C 89.0 PASS DP=6848;AF=0.002629;SB=2;DP4=3344,3456,13,17;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cCa|Q7P|419|N|protein_coding|CODING|GU280_gp10|1|C) +NC_045512.2 28311 . C T 49314.0 PASS DP=6942;AF=0.876549;SB=21;DP4=2,13,3390,3510;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cTc|P13L|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28361 . GGAGAACGCA G 49314.0 PASS DP=6081;AF=0.834402;SB=1;DP4=487,527,2473,2601;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggagaacgcagt/ggt|GERS30G|419|N|protein_coding|CODING|GU280_gp10|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 28363 . AGAACGCAGT A 281.0 PASS DP=5160;AF=0.005039;SB=54;DP4=2506,2638,24,2;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gaacgcagtggg/ggg|ERSG31G|419|N|protein_coding|CODING|GU280_gp10|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 28484 . G T 3814.0 PASS DP=4197;AF=0.046938;SB=0;DP4=1967,2004,106,109;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggc/Tgc|G71C|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28881 . G A 49314.0 PASS DP=1478;AF=0.929635;SB=0;DP4=0,0,732,743;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGg/aAg|R203K|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28882 . G A 49270.0 PASS DP=1474;AF=0.901628;SB=0;DP4=1,2,728,730;EFF=SYNONYMOUS_CODING(LOW|SILENT|agG/agA|R203|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28883 . G C 49314.0 PASS DP=1474;AF=0.945726;SB=0;DP4=0,0,729,742;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gga/Cga|G204R|419|N|protein_coding|CODING|GU280_gp10|1|C) +NC_045512.2 29417 . T A 97.0 PASS DP=1186;AF=0.006745;SB=1;DP4=570,607,5,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tta/Ata|L382I|419|N|protein_coding|CODING|GU280_gp10|1|A) diff --git a/example_data/example_mave_data/input/sample-09.vcf b/example_data/example_mave_data/input/sample-09.vcf new file mode 100644 index 0000000..5214a60 --- /dev/null +++ b/example_data/example_mave_data/input/sample-09.vcf @@ -0,0 +1,218 @@ +##fileformat=VCFv4.0 +##FILTER= +##fileDate=20240114 +##source=lofreq call --verbose --ref reference.fa --call-indels --min-cov 5 --max-depth 1000000 --min-bq 30 --min-alt-bq 30 --min-mq 20 --max-mq 255 --min-jq 0 --min-alt-jq 0 --def-alt-jq 0 --sig 0.0005 --bonf dynamic --no-default-filter --no-default-filter -r NC_045512.2:1-7475 -o /data/jwd02f/main/066/348/66348164/tmp/lofreq2_call_parallelzjngpncq/0.vcf.gz reads.bam +##reference=reference.fa +##INFO= +##INFO= --min-bq among all bases at the site"> +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##INFO= +##bcftools_annotateVersion=1.10.2+htslib-1.10.2 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites -AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 22:07:59 2024 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites +AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 22:09:18 2024 +##SnpEffVersion="4.5covid19 (build 2020-04-15 22:26), by Pablo Cingolani" +##SnpEffCmd="SnpEff -i vcf -o vcf -formatEff -classic -no-downstream -no-intergenic -no-upstream -stats /data/jwd02f/main/066/348/66348344/outputs/dataset_b0560374-ac2b-4413-85d4-d57d00739e7d.dat NC_045512.2 /data/dnb09/galaxy_db/files/7/0/3/dataset_7035947d-df70-432a-911f-d26afe290877.dat " +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +NC_045512.2 241 . C T 49314.0 PASS DP=1968;AF=0.932419;SB=0;DP4=2,3,978,980 +NC_045512.2 401 . C T 89.0 PASS DP=7352;AF=0.001768;SB=37;DP4=3809,3517,17,1;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L46F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L46F|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L46F|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|T|WARNING_TRANSCRIPT_NO_STOP_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L46F|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T) +NC_045512.2 443 . GT G 275.0 PASS DP=7947;AF=0.002643;SB=0;DP4=4073,3847,11,10;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttg/|L61|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 443 . GTT G 76.0 PASS DP=7947;AF=0.001007;SB=0;DP4=4073,3847,4,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttg/|L61|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L61|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 463 . GC G 102.0 PASS DP=9354;AF=0.001069;SB=2;DP4=4835,4513,4,6;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||ccc/|P67|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ccc/|P67|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ccc/|P67|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ccc/|P67|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 507 . ATGGTCATGTTATGGT A 300.0 PASS DP=9473;AF=0.002322;SB=0;DP4=4722,4727,11,11;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtcatgttatggttgag/gag|GHVMVE82E|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 509 . GGTCATGTTATGGTT G 505.0 PASS DP=9469;AF=0.003591;SB=0;DP4=4721,4726,17,17;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 518 . ATGGTT A 106.0 PASS DP=9525;AF=0.00105;SB=0;DP4=4843,4855,5,5;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||atggtt/|MV85|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),FRAME_SHIFT(HIGH||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||atggtt/|MV85|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||atggtt/|MV85|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 518 . ATG A 77.0 PASS DP=9525;AF=0.00084;SB=1;DP4=4843,4855,3,5;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||atg/|M85|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),FRAME_SHIFT(HIGH||atg/|M85|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||atg/|M85|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),FRAME_SHIFT(HIGH||atg/|M85|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 578 . G A 151.0 PASS DP=8839;AF=0.002489;SB=75;DP4=4408,4393,0,26;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G105S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G105S|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G105S|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G105S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A) +NC_045512.2 685 . AAAGTCATTT A 115.0 PASS DP=7032;AF=0.001422;SB=0;DP4=3501,3553,5,5;INDEL;HRUN=3;EFF=CODON_DELETION(MODERATE||aagtcattt/|KSF141|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_DELETION(MODERATE||aagtcattt/|KSF141|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_DELETION(MODERATE||aagtcattt/|KSF141|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),CODON_DELETION(MODERATE||aagtcattt/|KSF141|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A) +NC_045512.2 1887 . C T 94.0 PASS DP=7615;AF=0.002101;SB=19;DP4=3806,3769,18,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A541V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A541V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A361V|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A361V|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 1931 . C T 149.0 PASS DP=8151;AF=0.002331;SB=35;DP4=4245,3872,19,2;EFF=STOP_GAINED(HIGH|NONSENSE|Caa/Taa|Q556*|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),STOP_GAINED(HIGH|NONSENSE|Caa/Taa|Q556*|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),STOP_GAINED(HIGH|NONSENSE|Caa/Taa|Q376*|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),STOP_GAINED(HIGH|NONSENSE|Caa/Taa|Q376*|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.04);NMD=(ORF1ab|GU280_gp01|28|0.04) +NC_045512.2 2047 . T A 121.0 PASS DP=11700;AF=0.001624;SB=56;DP4=5841,5794,5,33;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N594K|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N594K|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N414K|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N414K|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2117 . G A 93.0 PASS DP=9958;AF=0.001506;SB=35;DP4=4852,5064,3,21;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggc/Agc|G618S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggc/Agc|G618S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggc/Agc|G438S|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggc/Agc|G438S|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2202 . G A 85.0 PASS DP=6479;AF=0.002006;SB=47;DP4=3338,3116,0,15;EFF=STOP_GAINED(HIGH|NONSENSE|tGg/tAg|W646*|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),STOP_GAINED(HIGH|NONSENSE|tGg/tAg|W646*|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),STOP_GAINED(HIGH|NONSENSE|tGg/tAg|W466*|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),STOP_GAINED(HIGH|NONSENSE|tGg/tAg|W466*|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.04);NMD=(ORF1ab|GU280_gp01|28|0.04) +NC_045512.2 2330 . T A 129.0 PASS DP=4352;AF=0.003217;SB=2;DP4=2142,2162,13,10;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2403 . CA C 73.0 PASS DP=4381;AF=0.00137;SB=0;DP4=2187,2188,3,3;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||aag/|K714|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K714|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K534|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K534|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 2477 . G A 82.0 PASS DP=2269;AF=0.003526;SB=22;DP4=1030,1229,0,9;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gaa/Aaa|E738K|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gaa/Aaa|E738K|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gaa/Aaa|E558K|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gaa/Aaa|E558K|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2637 . T A 83.0 PASS DP=7832;AF=0.00166;SB=53;DP4=3905,3881,3,28;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cTc/cAc|L791H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cTc/cAc|L791H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cTc/cAc|L611H|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cTc/cAc|L611H|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2710 . CA C 112.0 PASS DP=7951;AF=0.001258;SB=0;DP4=3976,3977,5,5;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||aaa/|K816|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K816|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K636|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K636|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 2832 . A G 49314.0 PASS DP=4590;AF=0.930937;SB=8;DP4=1,6,2140,2433;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3036 . TC T 85.0 PASS DP=2796;AF=0.002146;SB=0;DP4=1347,1447,3,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||ttc/|F924|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),FRAME_SHIFT(HIGH||ttc/|F924|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),FRAME_SHIFT(HIGH||ttc/|F106|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),FRAME_SHIFT(HIGH||ttc/|F106|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 3037 . C T 49314.0 PASS DP=2796;AF=0.935265;SB=0;DP4=1,1,1341,1436;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3722 . AT A 75.0 PASS DP=4484;AF=0.001561;SB=0;DP4=2140,2345,3,4;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||ttt/|F1154|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F1154|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F336|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F336|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 4174 . TA T 163.0 PASS DP=3443;AF=0.003485;SB=0;DP4=1715,1716,6,6;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aag/|K1305|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K1305|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K487|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K487|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 4825 . T C 105.0 PASS DP=8193;AF=0.001831;SB=0;DP4=4087,4084,8,8;EFF=SYNONYMOUS_CODING(LOW|SILENT|tcT/tcC|S1520|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|tcT/tcC|S1520|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|tcT/tcC|S702|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|tcT/tcC|S702|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 4975 . G A 91.0 PASS DP=7517;AF=0.001995;SB=60;DP4=3763,3726,0,20;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtG/gtA|V1570|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),SYNONYMOUS_CODING(LOW|SILENT|gtG/gtA|V1570|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),SYNONYMOUS_CODING(LOW|SILENT|gtG/gtA|V752|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtG/gtA|V752|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5085 . TA T 101.0 PASS DP=8812;AF=0.001135;SB=0;DP4=4411,4403,5,5;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||aaa/|K1608|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K1608|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K790|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K790|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 5157 . CT C 100.0 PASS DP=8873;AF=0.001127;SB=0;DP4=4459,4459,5,5;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttt/|F1632|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F1632|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F814|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F814|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 5386 . T G 49314.0 PASS DP=7052;AF=0.914634;SB=0;DP4=5,4,3519,3509;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5595 . A T 82.0 PASS DP=6966;AF=0.001723;SB=43;DP4=3426,3498,23,3;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gTa|E1777V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gTa|E1777V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gTa|E959V|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gTa|E959V|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5743 . G C 4413.0 PASS DP=9956;AF=0.027923;SB=0;DP4=4827,4814,152,152;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5744 . T C 4263.0 PASS DP=9950;AF=0.027437;SB=1;DP4=4805,4819,156,149;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6148 . T C 122.0 PASS DP=3054;AF=0.005566;SB=11;DP4=1425,1600,7,18;EFF=SYNONYMOUS_CODING(LOW|SILENT|ccT/ccC|P1961|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|ccT/ccC|P1961|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|ccT/ccC|P1143|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ccT/ccC|P1143|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6512 . AGTT A 49314.0 PASS DP=2638;AF=0.992419;SB=3;DP4=11,7,1354,1264;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 7246 . GT G 112.0 PASS DP=5407;AF=0.001849;SB=0;DP4=2720,2715,5,5;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||ttg/|L2329|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L2329|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L1511|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L1511|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 7813 . TTC T 70.0 PASS DP=5121;AF=0.001172;SB=0;DP4=2600,2520,3,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||tctcat/|SH2519|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tctcat/|SH2519|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tctcat/|SH1701|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tctcat/|SH1701|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 8376 . CA C 103.0 PASS DP=4699;AF=0.001915;SB=1;DP4=2567,2120,4,5;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||agt/|S2706|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||agt/|S2706|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||agt/|S1888|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||agt/|S1888|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 8393 . G A 49314.0 PASS DP=5402;AF=0.935579;SB=1;DP4=4,2,2952,2424;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 8464 . TA T 74.0 PASS DP=7163;AF=0.001117;SB=0;DP4=3579,3576,4,4;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aag/|K2735|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K2735|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K1917|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K1917|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 9166 . C T 323.0 PASS DP=3795;AF=0.007378;SB=0;DP4=1879,1880,17,16;EFF=SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T2967|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T2967|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T204|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T204|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10029 . C T 49314.0 PASS DP=8452;AF=0.88831;SB=9;DP4=2,7,4219,4189;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10323 . A G 144.0 PASS DP=7296;AF=0.002467;SB=1;DP4=3626,3629,12,9;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K3353R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K3353R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K90R|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K90R|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10449 . C A 49314.0 PASS DP=6718;AF=0.898035;SB=35;DP4=4,23,3302,3357;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10484 . T G 382.0 PASS DP=5387;AF=0.006497;SB=0;DP4=2861,2476,23,20;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10541 . C A 341.0 PASS DP=7183;AF=0.004733;SB=13;DP4=3627,3488,22,36;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10563 . G A 98.0 PASS DP=7572;AF=0.001849;SB=10;DP4=3771,3770,5,13;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGa/gAa|G3433E|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGa/gAa|G3433E|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGa/gAa|G170E|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGa/gAa|G170E|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10594 . CT C 111.0 PASS DP=7640;AF=0.00144;SB=0;DP4=3821,3826,5,6;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tat/|Y3445|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tat/|Y3445|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tat/|Y182|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tat/|Y182|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 10605 . CT C 167.0 PASS DP=7578;AF=0.001847;SB=0;DP4=3792,3798,7,7;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttt/|F3448|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F3448|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F185|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F185|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 10932 . CT C 67.0 PASS DP=5881;AF=0.00119;SB=1;DP4=2974,2968,3,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttt/|F3557|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F3557|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F294|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F294|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 11074 . C CT 546.0 PASS DP=7429;AF=0.01023;SB=0;DP4=3943,3551,40,36;INDEL;HRUN=8;EFF=FRAME_SHIFT(HIGH||ttg/ttTg|L3606F?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/ttTg|L3606F?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/ttTg|L37F?|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/ttTg|L37F?|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11074 . CT C 5355.0 PASS DP=7429;AF=0.052093;SB=0;DP4=3775,3400,204,183;INDEL;HRUN=8;EFF=FRAME_SHIFT(HIGH||ttg/|L3606|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L3606|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L37|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L37|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11082 . TG T 102.0 PASS DP=7394;AF=0.001352;SB=2;DP4=3864,3538,4,6;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||ttg/|L3606|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),FRAME_SHIFT(HIGH||ttg/|L3606|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),FRAME_SHIFT(HIGH||ttg/|L37|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),FRAME_SHIFT(HIGH||ttg/|L37|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11211 . AT A 71.0 PASS DP=9814;AF=0.000815;SB=0;DP4=4897,4909,4,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttt/|F3650|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F3650|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F81|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F81|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11282 . AGTTTGTCTG A 49314.0 PASS DP=8567;AF=0.930781;SB=8;DP4=269,323,3871,4103;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 11521 . GT G 89.0 PASS DP=9272;AF=0.001079;SB=0;DP4=4664,4667,5,5;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||ttg/|L3754|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L3754|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L185|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L185|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11537 . A G 49314.0 PASS DP=9217;AF=0.932299;SB=1;DP4=2,4,4595,4599;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11653 . CT C 85.0 PASS DP=6467;AF=0.001237;SB=0;DP4=3034,3430,4,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tgt/|C3798|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgt/|C3798|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgt/|C229|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgt/|C229|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11679 . G A 110.0 PASS DP=7146;AF=0.002239;SB=35;DP4=3436,3681,1,16;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGa/aAa|R3805K|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGa/aAa|R3805K|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGa/aAa|R236K|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGa/aAa|R236K|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 12242 . C T 178.0 PASS DP=5768;AF=0.003467;SB=0;DP4=2686,3044,12,13;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cgt/Tgt|R3993C|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cgt/Tgt|R3993C|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cgt/Tgt|R51C|197|ORF1ab|protein_coding|CODING|YP_009725304.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cgt/Tgt|R51C|197|ORF1ab|protein_coding|CODING|YP_009742615.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 12410 . A G 124.0 PASS DP=7083;AF=0.002259;SB=0;DP4=3523,3522,10,9;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Atc/Gtc|I4049V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Atc/Gtc|I4049V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Atc/Gtc|I107V|197|ORF1ab|protein_coding|CODING|YP_009725304.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Atc/Gtc|I107V|197|ORF1ab|protein_coding|CODING|YP_009742615.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13078 . T C 85.0 PASS DP=9859;AF=0.00142;SB=0;DP4=4909,4906,9,7;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcT/gcC|A4271|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcC|A4271|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcC|A18|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcC|A18|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13123 . TG T 145.0 PASS DP=8657;AF=0.001617;SB=0;DP4=4151,4504,7,7;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||gga/|G4288|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gga/|G4288|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gga/|G35|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gga/|G35|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.11) +NC_045512.2 13195 . T C 49314.0 PASS DP=9555;AF=0.917739;SB=6;DP4=8,3,5025,4515;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13282 . TA T 76.0 PASS DP=10623;AF=0.000753;SB=0;DP4=5312,5303,4,4;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||aaa/|K4340|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K4340|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K87|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K87|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.11) +NC_045512.2 13459 . GT G 79.0 PASS DP=7345;AF=0.001225;SB=0;DP4=3317,4092,4,5;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||tta/|L4400|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L4400|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L8|12|ORF1ab|protein_coding|CODING|YP_009725312.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L8|931|ORF1ab|protein_coding|CODING|YP_009725307.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 14407 . CCTACAAG C 90.0 PASS DP=5526;AF=0.001629;SB=1;DP4=2934,2709,4,5;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||cctacaagt/|PTS4715|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),FRAME_SHIFT(HIGH||cctacaagt/|PTS323|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 14408 . C T 49314.0 PASS DP=5527;AF=0.945359;SB=0;DP4=2,1,2871,2636;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P4715L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P323L|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 14432 . GA G 148.0 PASS DP=4843;AF=0.002478;SB=0;DP4=2570,2261,6,6;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||ata/|I4725|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ata/|I333|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 15106 . A C 162.0 PASS DP=5069;AF=0.003551;SB=728;DP4=2566,2233,0,227;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Acc/Ccc|T4948P|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Acc/Ccc|T556P|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15157 . CA C 98.0 PASS DP=5177;AF=0.001738;SB=0;DP4=2602,2566,5,4;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aaa/|K4966|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K574|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 15240 . C T 49314.0 PASS DP=4662;AF=0.939296;SB=0;DP4=2,2,2217,2432;EFF=SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N4992|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N600|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15521 . T A 327.0 PASS DP=328;AF=0.04878;SB=0;DP4=151,161,8,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTt/tAt|F5086Y|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTt/tAt|F694Y|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15579 . CA C 100.0 PASS DP=3972;AF=0.002014;SB=0;DP4=2154,1812,4,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||att/|I5107|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||att/|I715|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 15738 . C T 187.0 PASS DP=9393;AF=0.002449;SB=1;DP4=4668,4676,15,13;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F5158|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F766|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15830 . CA C 78.0 PASS DP=7977;AF=0.001003;SB=0;DP4=3836,4195,4,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||aaa/|K5190|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K798|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 15983 . TA T 168.0 PASS DP=9569;AF=0.001672;SB=0;DP4=4954,4601,8,8;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aca/|T5242|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aca/|T850|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 16215 . C T 82.0 PASS DP=14679;AF=0.001294;SB=0;DP4=7154,7469,14,13;EFF=SYNONYMOUS_CODING(LOW|SILENT|taC/taT|Y5317|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|taC/taT|Y925|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 16837 . GA G 66.0 PASS DP=9291;AF=0.000861;SB=0;DP4=4794,4489,4,4;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aaa/|K5526|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K202|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 17068 . T A 177.0 PASS DP=10381;AF=0.002312;SB=87;DP4=5003,5325,1,35;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tct/Act|S5602T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tct/Act|S278T|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 17079 . G A 198.0 PASS DP=9461;AF=0.002748;SB=62;DP4=4540,4873,1,26;EFF=SYNONYMOUS_CODING(LOW|SILENT|caG/caA|Q5605|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),SYNONYMOUS_CODING(LOW|SILENT|caG/caA|Q281|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 17144 . G A 251.0 PASS DP=4667;AF=0.005142;SB=9;DP4=2336,2301,9,17;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cGc/cAc|R5627H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cGc/cAc|R303H|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 17285 . C T 27513.0 PASS DP=5402;AF=0.19104;SB=0;DP4=2113,2216,520,545;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCa/tTa|S5674L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCa/tTa|S350L|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 17652 . TA T 71.0 PASS DP=6476;AF=0.001081;SB=1;DP4=3244,3234,3,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||atg/|M5798|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||atg/|M474|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 17723 . TA T 75.0 PASS DP=3621;AF=0.001657;SB=0;DP4=1844,1773,3,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||aga/|R5821|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aga/|R497|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 18163 . A G 43398.0 PASS DP=1276;AF=0.927116;SB=0;DP4=0,0,638,636;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I5967V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I42V|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18687 . CT C 221.0 PASS DP=5361;AF=0.002985;SB=0;DP4=2727,2662,8,8;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tcc/|S6143|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tcc/|S218|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 19066 . C T 108.0 PASS DP=10531;AF=0.001614;SB=28;DP4=5237,5257,19,4;EFF=STOP_GAINED(HIGH|NONSENSE|Caa/Taa|Q6268*|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),STOP_GAINED(HIGH|NONSENSE|Caa/Taa|Q343*|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 19188 . AT A 106.0 PASS DP=7679;AF=0.001302;SB=0;DP4=3680,4009,5,5;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tgg/|W6310|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgg/|W385|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 19387 . A T 104.0 PASS DP=1733;AF=0.005193;SB=0;DP4=857,860,5,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Agt/Tgt|S6375C|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Agt/Tgt|S450C|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 20360 . GT G 74.0 PASS DP=6936;AF=0.001009;SB=0;DP4=3407,3738,3,4;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||tta/|L6700|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L248|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 20464 . G A 107.0 PASS DP=6735;AF=0.002227;SB=35;DP4=3325,3389,1,16;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gat/Aat|D6734N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gat/Aat|D282N|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 20625 . TG T 66.0 PASS DP=5540;AF=0.001083;SB=0;DP4=2768,2768,3,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggc/|G6788|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggc/|G336|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 20930 . C T 91.0 PASS DP=4828;AF=0.002486;SB=3;DP4=2400,2407,9,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCg/aTg|T6889M|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCg/aTg|T91M|297|ORF1ab|protein_coding|CODING|YP_009725311.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 21123 . GT G 96.0 PASS DP=5416;AF=0.001477;SB=0;DP4=2767,2683,4,4;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||ttt/|F6954|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F156|297|ORF1ab|protein_coding|CODING|YP_009725311.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.04) +NC_045512.2 21651 . A G 90.0 PASS DP=8050;AF=0.001739;SB=5;DP4=4032,3976,13,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAt/aGt|N30S|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 21740 . TCCAATGTTACTTGGTTCCATGCTATACATGTCTCTGGGA T 633.0 PASS DP=6125;AF=0.005878;SB=0;DP4=3046,3043,18,18;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttacttggttccatgctatacatgtctctgggaccaatggt/ggt|VTWFHAIHVSGTNG62G|1273|S|protein_coding|CODING|GU280_gp02|1|T|INFO_REALIGN_3_PRIME) +NC_045512.2 21762 . C T 49314.0 PASS DP=5640;AF=0.944681;SB=0;DP4=2,3,2781,2797;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A67V|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21764 . ATACATG A 49314.0 PASS DP=5441;AF=0.990443;SB=3;DP4=26,33,2696,2693;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||atacatgtc/atc|IHV68I|1273|S|protein_coding|CODING|GU280_gp02|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 21834 . AT A 66.0 PASS DP=4681;AF=0.001282;SB=0;DP4=2307,2382,3,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttt/|F92|1273|S|protein_coding|CODING|GU280_gp02|1|A|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 21846 . C T 49314.0 PASS DP=4500;AF=0.944222;SB=0;DP4=1,2,2201,2290;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T95I|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21890 . TTA T 72.0 PASS DP=3537;AF=0.001696;SB=0;DP4=1742,1835,3,3;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||tta/|L110|1273|S|protein_coding|CODING|GU280_gp02|1|T);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 21985 . GGGTGTTTAT G 121.0 PASS DP=2979;AF=0.004028;SB=1;DP4=1548,1415,7,5;INDEL;HRUN=3;EFF=CODON_DELETION(MODERATE||ggtgtttat/|GVY142|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 21986 . GGTGTTTATT G 49314.0 PASS DP=2935;AF=0.989097;SB=5;DP4=35,41,1522,1381;INDEL;HRUN=3;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtgtttattac/gac|GVYY142D|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 21987 . GTGTTTATTA G 82.0 PASS DP=2935;AF=0.003407;SB=0;DP4=1534,1390,5,5;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtgtttattac/ggc|GVYY142G|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 22104 . GA G 101.0 PASS DP=4004;AF=0.001998;SB=0;DP4=2044,2046,4,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||aaa/|K182|1273|S|protein_coding|CODING|GU280_gp02|1|G|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 22193 . AATT A 49314.0 PASS DP=3283;AF=0.911666;SB=77;DP4=465,702,1483,1510;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattta/ata|NL211I|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22204 . T TGAGCCAGAA 49314.0 PASS DP=2765;AF=0.798192;SB=1;DP4=239,265,1069,1138;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGAAGAt|D215EPED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22204 . T TGAGCCTGAA 83.0 PASS DP=2765;AF=0.00217;SB=1;DP4=239,265,2,4;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCTGAAGAt|D215EPED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCTGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22204 . T TGAGCAAGAA 118.0 PASS DP=2765;AF=0.002893;SB=5;DP4=239,265,2,6;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCAAGAAGAt|D215EQED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCAAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22204 . T TGAGCCAGCA 81.0 PASS DP=2765;AF=0.00217;SB=0;DP4=239,265,3,3;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGCAGAt|D215EPAD|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGCA|INFO_REALIGN_3_PRIME) +NC_045512.2 22204 . T TGATCCAGAA 118.0 PASS DP=2765;AF=0.002893;SB=15;DP4=239,265,7,1;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||ctc/cCAGAAGATCtc|L216PEDL|1273|S|protein_coding|CODING|GU280_gp02|1|TGATCCAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22578 . G A 49314.0 PASS DP=4984;AF=0.95004;SB=0;DP4=2,1,2486,2484;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGt/gAt|G339D|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22583 . GT G 85.0 PASS DP=4986;AF=0.001604;SB=0;DP4=2495,2491,4,4;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||ttt/|F342|1273|S|protein_coding|CODING|GU280_gp02|1|G|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 22661 . G T 49314.0 PASS DP=3934;AF=0.593035;SB=1;DP4=719,740,1233,1239;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtc/Ttc|V367F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22667 . T C 6108.0 PASS DP=3505;AF=0.079886;SB=0;DP4=1568,1637,145,153;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tat/Cat|Y369H|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22673 . T C 49314.0 PASS DP=2517;AF=0.923321;SB=1;DP4=14,16,1057,1426;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tcc/Ccc|S371P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22674 . C T 49314.0 PASS DP=2510;AF=0.892829;SB=1;DP4=1,3,1062,1422;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S371F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22679 . T C 49314.0 PASS DP=2660;AF=0.92782;SB=3;DP4=1,0,1142,1512;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Cca|S373P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22686 . C T 49314.0 PASS DP=2692;AF=0.945765;SB=0;DP4=2,4,1149,1531;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S375F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22713 . C T 3289.0 PASS DP=2252;AF=0.068384;SB=0;DP4=913,1175,68,92;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P384L|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22992 . G A 49314.0 PASS DP=1670;AF=0.929341;SB=0;DP4=0,0,896,764;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGc/aAc|S477N|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22995 . C A 49314.0 PASS DP=1694;AF=0.929162;SB=9;DP4=0,3,902,783;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T478K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23013 . A C 49314.0 PASS DP=2402;AF=0.939217;SB=0;DP4=2,2,1303,1092;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gCa|E484A|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23040 . A G 49314.0 PASS DP=3058;AF=0.942446;SB=6;DP4=0,2,1608,1445;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q493R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23048 . G A 49314.0 PASS DP=3572;AF=0.959406;SB=0;DP4=4,4,1872,1690;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G496S|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23055 . A G 49314.0 PASS DP=3703;AF=0.923035;SB=3;DP4=0,1,1940,1755;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q498R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23063 . A T 49314.0 PASS DP=4339;AF=0.952985;SB=3;DP4=0,1,2283,2047;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aat/Tat|N501Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23075 . T C 49314.0 PASS DP=4435;AF=0.928523;SB=3;DP4=5,2,2313,2110;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y505H|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23143 . TA T 87.0 PASS DP=6215;AF=0.001448;SB=0;DP4=3104,3103,5,4;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aag/|K529|1273|S|protein_coding|CODING|GU280_gp02|1|T|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 23201 . AC A 82.0 PASS DP=6121;AF=0.001307;SB=2;DP4=3058,3068,5,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||aca/|T547|1273|S|protein_coding|CODING|GU280_gp02|1|A);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 23202 . C A 49314.0 PASS DP=6121;AF=0.94527;SB=3;DP4=0,2,3043,3065;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T547K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23230 . CA C 84.0 PASS DP=5328;AF=0.001502;SB=0;DP4=2634,2742,4,4;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aag/|K558|1273|S|protein_coding|CODING|GU280_gp02|1|C|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 23403 . A G 49314.0 PASS DP=9967;AF=0.93027;SB=5;DP4=5,2,4961,4973;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D614G|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23525 . C T 49314.0 PASS DP=8263;AF=0.943483;SB=0;DP4=0,1,3975,4269;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cat/Tat|H655Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23540 . T C 93.0 PASS DP=7325;AF=0.001911;SB=3;DP4=3426,3860,10,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tat/Cat|Y660H|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23599 . T G 49314.0 PASS DP=3513;AF=0.936806;SB=0;DP4=1,1,1624,1882;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaG|N679K|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23604 . C A 49314.0 PASS DP=2953;AF=0.932611;SB=3;DP4=2,5,1348,1592;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cAt|P681H|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23854 . C A 224.0 PASS DP=6;AF=1;SB=0;DP4=0,0,3,3;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaC/aaA|N764K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23948 . G T 49314.0 PASS DP=1559;AF=0.917896;SB=2;DP4=2,1,760,790;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gat/Tat|D796Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24130 . C A 49314.0 PASS DP=2618;AF=0.911001;SB=0;DP4=0,1,1249,1355;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaC/aaA|N856K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24320 . CA C 126.0 PASS DP=7381;AF=0.001626;SB=0;DP4=3690,3685,6,6;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aaa/|K921|1273|S|protein_coding|CODING|GU280_gp02|1|C|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 24424 . A T 49314.0 PASS DP=7163;AF=0.94667;SB=14;DP4=1,7,3581,3571;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caT|Q954H|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24469 . T A 49314.0 PASS DP=7536;AF=0.92768;SB=28;DP4=17,3,3741,3757;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N969K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24503 . C T 49314.0 PASS DP=7699;AF=0.934407;SB=6;DP4=5,11,3746,3922;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L981F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24530 . G A 113.0 PASS DP=7291;AF=0.002057;SB=50;DP4=3514,3754,0,18;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gaa/Aaa|E990K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24672 . CA C 127.0 PASS DP=5402;AF=0.002036;SB=1;DP4=2695,2700,6,5;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aga/|R1039|1273|S|protein_coding|CODING|GU280_gp02|1|C|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 24798 . C T 107.0 PASS DP=4203;AF=0.003093;SB=18;DP4=2137,2048,12,2;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P1079L|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24858 . G A 100.0 PASS DP=4472;AF=0.002683;SB=5;DP4=2287,2150,9,14;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGc/gAc|G1099D|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24878 . CA C 102.0 PASS DP=4832;AF=0.001656;SB=0;DP4=2466,2427,4,4;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||agg/|R1107|1273|S|protein_coding|CODING|GU280_gp02|1|C|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 25000 . C T 49314.0 PASS DP=4335;AF=0.928028;SB=12;DP4=0,5,2160,2161;EFF=SYNONYMOUS_CODING(LOW|SILENT|gaC/gaT|D1146|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25381 . A C 85.0 PASS DP=6731;AF=0.002228;SB=2;DP4=3399,3305,10,7;EFF=SYNONYMOUS_CODING(LOW|SILENT|acA/acC|T1273|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 25584 . C T 49314.0 PASS DP=6203;AF=0.90956;SB=3;DP4=2,5,3086,3088;EFF=SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T64|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 25613 . C T 206.0 PASS DP=6306;AF=0.003647;SB=4;DP4=2900,3363,11,19;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S74F|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 25771 . C T 81.0 PASS DP=6266;AF=0.001915;SB=12;DP4=3250,2989,13,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L127F|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 25797 . CA C 313.0 PASS DP=6569;AF=0.003654;SB=0;DP4=3274,3271,12,12;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aac/|N137|275|ORF3a|protein_coding|CODING|GU280_gp03|1|C|INFO_REALIGN_3_PRIME);LOF=(ORF3a|GU280_gp03|1|1.00) +NC_045512.2 26211 . G A 100.0 PASS DP=9850;AF=0.001827;SB=54;DP4=4910,4901,0,19;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtG/gtA|V273|275|ORF3a|protein_coding|CODING|GU280_gp03|1|A) +NC_045512.2 26270 . C T 49314.0 PASS DP=8324;AF=0.918549;SB=2;DP4=6,10,3860,4424;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aTa|T9I|75|E|protein_coding|CODING|GU280_gp04|1|T) +NC_045512.2 26325 . G A 297.0 PASS DP=6204;AF=0.004674;SB=59;DP4=2641,3519,1,30;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttG/ttA|L27|75|E|protein_coding|CODING|GU280_gp04|1|A) +NC_045512.2 26440 . A T 85.0 PASS DP=3050;AF=0.002951;SB=36;DP4=1507,1524,12,0;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aat/Tat|N66Y|75|E|protein_coding|CODING|GU280_gp04|1|T) +NC_045512.2 26461 . C T 102.0 PASS DP=2637;AF=0.003792;SB=0;DP4=1275,1349,6,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L73F|75|E|protein_coding|CODING|GU280_gp04|1|T) +NC_045512.2 26530 . A G 49314.0 PASS DP=2720;AF=0.924265;SB=0;DP4=0,0,1319,1395;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D3G|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26577 . C G 39597.0 PASS DP=1149;AF=0.929504;SB=0;DP4=2,2,560,581;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Gaa|Q19E|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26709 . G A 14818.0 PASS DP=448;AF=0.895089;SB=1;DP4=2,3,227,209;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A63T|222|M|protein_coding|CODING|GU280_gp05|1|A) +NC_045512.2 26767 . T C 171.0 PASS DP=496;AF=0.020161;SB=0;DP4=245,239,5,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aTc/aCc|I82T|222|M|protein_coding|CODING|GU280_gp05|1|C) +NC_045512.2 27259 . A C 49314.0 PASS DP=5010;AF=0.938124;SB=1;DP4=2,3,2617,2385;EFF=SYNONYMOUS_CODING(LOW|SILENT|Agg/Cgg|R20|61|ORF6|protein_coding|CODING|GU280_gp06|1|C) +NC_045512.2 27384 . T C 198.0 PASS DP=6663;AF=0.003602;SB=0;DP4=3312,3312,14,13;EFF=SYNONYMOUS_CODING(LOW|SILENT|gaT/gaC|D61|61|ORF6|protein_coding|CODING|GU280_gp06|1|C) +NC_045512.2 27605 . TA T 104.0 PASS DP=3640;AF=0.002198;SB=0;DP4=1818,1818,4,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||aaa/|K72|121|ORF7a|protein_coding|CODING|GU280_gp07|1|T|INFO_REALIGN_3_PRIME);LOF=(ORF7a|GU280_gp07|1|1.00) +NC_045512.2 27807 . C T 49314.0 PASS DP=7410;AF=0.94251;SB=3;DP4=2,4,3695,3683;EFF=SYNONYMOUS_CODING(LOW|SILENT|Cta/Tta|L18|43|ORF7b|protein_coding|CODING|GU280_gp08|1|T) +NC_045512.2 27984 . T C 98.0 PASS DP=5560;AF=0.002338;SB=3;DP4=2551,2976,7,12;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tat/Cat|Y31H|121|ORF8|protein_coding|CODING|GU280_gp09|1|C) +NC_045512.2 28001 . G A 92.0 PASS DP=4726;AF=0.002539;SB=0;DP4=2151,2552,6,9;EFF=SYNONYMOUS_CODING(LOW|SILENT|ccG/ccA|P36|121|ORF8|protein_coding|CODING|GU280_gp09|1|A) +NC_045512.2 28250 . T TG 2905.0 PASS DP=8012;AF=0.024713;SB=3;DP4=4125,4003,106,92;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||ttc/Gttc|F120V?|121|ORF8|protein_coding|CODING|GU280_gp09|1|TG) +NC_045512.2 28251 . T G 9019.0 PASS DP=8013;AF=0.061525;SB=2;DP4=3794,3643,271,277;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ttc/Gtc|F120V|121|ORF8|protein_coding|CODING|GU280_gp09|1|G) +NC_045512.2 28253 . CA C 2970.0 PASS DP=8033;AF=0.025022;SB=3;DP4=3963,3875,107,94;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||atc/|I121|121|ORF8|protein_coding|CODING|GU280_gp09|1|C) +NC_045512.2 28253 . C T 9090.0 PASS DP=8039;AF=0.06145;SB=1;DP4=3789,3687,272,276;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F120|121|ORF8|protein_coding|CODING|GU280_gp09|1|T) +NC_045512.2 28254 . A C 10854.0 PASS DP=8054;AF=0.062702;SB=4;DP4=3686,3593,271,286;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Atc/Ctc|I121L|121|ORF8|protein_coding|CODING|GU280_gp09|1|C) +NC_045512.2 28271 . A T 49314.0 PASS DP=9205;AF=0.948723;SB=16;DP4=1,9,4592,4591 +NC_045512.2 28311 . C T 49314.0 PASS DP=9355;AF=0.878033;SB=27;DP4=5,22,4543,4741;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cTc|P13L|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28361 . GGAGAACGCA G 49314.0 PASS DP=8154;AF=0.841182;SB=3;DP4=611,693,3292,3567;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggagaacgcagt/ggt|GERS30G|419|N|protein_coding|CODING|GU280_gp10|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 28363 . AGAACGCAGT A 496.0 PASS DP=6970;AF=0.00703;SB=72;DP4=3333,3606,42,7;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gaacgcagtggg/ggg|ERSG31G|419|N|protein_coding|CODING|GU280_gp10|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 28720 . C T 110.0 PASS DP=6341;AF=0.002366;SB=0;DP4=3158,3156,11,10;EFF=SYNONYMOUS_CODING(LOW|SILENT|cgC/cgT|R149|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28881 . G A 49314.0 PASS DP=3638;AF=0.917262;SB=0;DP4=3,2,1833,1786;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGg/aAg|R203K|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28882 . G A 49314.0 PASS DP=3628;AF=0.888093;SB=4;DP4=4,7,1829,1759;EFF=SYNONYMOUS_CODING(LOW|SILENT|agG/agA|R203|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28883 . G C 49314.0 PASS DP=3630;AF=0.934435;SB=0;DP4=3,3,1828,1789;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gga/Cga|G204R|419|N|protein_coding|CODING|GU280_gp10|1|C) +NC_045512.2 28936 . G T 100.0 PASS DP=4155;AF=0.002647;SB=748;DP4=1885,2014,248,0;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|ttG/ttT|L221F|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28981 . T G 94.0 PASS DP=5123;AF=0.002342;SB=994;DP4=2196,2574,323,2;EFF=SYNONYMOUS_CODING(LOW|SILENT|ggT/ggG|G236|419|N|protein_coding|CODING|GU280_gp10|1|G) +NC_045512.2 28987 . CCAA C 115.0 PASS DP=5117;AF=0.001759;SB=0;DP4=2575,2627,4,5;INDEL;HRUN=2;EFF=CODON_DELETION(MODERATE||caa/|Q242|419|N|protein_coding|CODING|GU280_gp10|1|C|INFO_REALIGN_3_PRIME) +NC_045512.2 29127 . AT A 118.0 PASS DP=3849;AF=0.002338;SB=0;DP4=1842,2003,4,5;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttt/|F286|419|N|protein_coding|CODING|GU280_gp10|1|A|INFO_REALIGN_3_PRIME);LOF=(N|GU280_gp10|1|1.00) +NC_045512.2 29494 . G A 121.0 PASS DP=3419;AF=0.004095;SB=45;DP4=1574,1820,0,17;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttG/ttA|L407|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 29675 . C A 100.0 PASS DP=1264;AF=0.006329;SB=2;DP4=625,628,6,4 diff --git a/example_data/example_mave_data/input/sample-10.vcf b/example_data/example_mave_data/input/sample-10.vcf new file mode 100644 index 0000000..2b835d7 --- /dev/null +++ b/example_data/example_mave_data/input/sample-10.vcf @@ -0,0 +1,196 @@ +##fileformat=VCFv4.0 +##FILTER= +##fileDate=20240114 +##source=lofreq call --verbose --ref reference.fa --call-indels --min-cov 5 --max-depth 1000000 --min-bq 30 --min-alt-bq 30 --min-mq 20 --max-mq 255 --min-jq 0 --min-alt-jq 0 --def-alt-jq 0 --sig 0.0005 --bonf dynamic --no-default-filter --no-default-filter -r NC_045512.2:1-7475 -o /data/jwd02f/main/066/348/66348165/tmp/lofreq2_call_parallelpamzhysv/0.vcf.gz reads.bam +##reference=reference.fa +##INFO= +##INFO= --min-bq among all bases at the site"> +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##INFO= +##bcftools_annotateVersion=1.10.2+htslib-1.10.2 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites -AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 22:23:37 2024 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites +AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 22:26:32 2024 +##SnpEffVersion="4.5covid19 (build 2020-04-15 22:26), by Pablo Cingolani" +##SnpEffCmd="SnpEff -i vcf -o vcf -formatEff -classic -no-downstream -no-intergenic -no-upstream -stats /data/jwd05e/main/066/348/66348345/outputs/dataset_0f7507a7-ba1f-4048-bd51-a918bd1f19a8.dat NC_045512.2 /data/dnb09/galaxy_db/files/1/f/6/dataset_1f6a10fa-8a58-4358-963f-a7b7d995ebf7.dat " +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +NC_045512.2 241 . C T 24373.0 PASS DP=715;AF=0.93007;SB=0;DP4=0,0,356,357 +NC_045512.2 434 . GA G 111.0 PASS DP=5482;AF=0.001824;SB=0;DP4=2846,2626,5,5;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aaa/|K58|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K58|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K58|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K58|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 509 . GGTCATGTTATGGTT G 118.0 PASS DP=6622;AF=0.00151;SB=0;DP4=3316,3312,5,5;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|G|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggtcatgttatggttgag/|GHVMVE82|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 578 . G A 81.0 PASS DP=6272;AF=0.001913;SB=27;DP4=3131,3119,1,13;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G105S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G105S|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G105S|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G105S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A) +NC_045512.2 738 . AAG A 120.0 PASS DP=2926;AF=0.002734;SB=0;DP4=1497,1421,4,4;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||gaa/|E159|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gaa/|E159|179|ORF1ab|protein_coding|CODING|YP_009725297.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gaa/|E159|179|ORF1ab|protein_coding|CODING|YP_009742608.1|1|A|WARNING_TRANSCRIPT_NO_STOP_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gaa/|E159|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 1066 . TG T 71.0 PASS DP=3837;AF=0.001564;SB=0;DP4=2002,1831,3,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||gaa/|E269|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gaa/|E269|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gaa/|E89|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gaa/|E89|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.11) +NC_045512.2 1806 . GA G 103.0 PASS DP=3870;AF=0.002067;SB=0;DP4=1827,2044,4,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||aaa/|K515|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K515|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K335|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K335|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 2330 . T A 141.0 PASS DP=2109;AF=0.00569;SB=0;DP4=1039,1046,7,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C689S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tgt/Agt|C509S|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2583 . C T 82.0 PASS DP=4477;AF=0.002234;SB=19;DP4=2331,2130,10,1;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A773V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A773V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A593V|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A593V|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2650 . C T 128.0 PASS DP=5748;AF=0.00261;SB=32;DP4=2856,2870,15,1;EFF=SYNONYMOUS_CODING(LOW|SILENT|gaC/gaT|D795|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|gaC/gaT|D795|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|gaC/gaT|D615|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gaC/gaT|D615|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 2832 . A G 49314.0 PASS DP=3064;AF=0.936684;SB=0;DP4=1,1,1417,1636;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K856R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aAg/aGg|K38R|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3036 . TC T 85.0 PASS DP=950;AF=0.005263;SB=0;DP4=450,495,2,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||ttc/|F924|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),FRAME_SHIFT(HIGH||ttc/|F924|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),FRAME_SHIFT(HIGH||ttc/|F106|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),FRAME_SHIFT(HIGH||ttc/|F106|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 3037 . C T 34280.0 PASS DP=950;AF=0.949474;SB=0;DP4=0,0,450,495;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3412 . TA T 201.0 PASS DP=3447;AF=0.004062;SB=0;DP4=1594,1850,7,7;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aag/|K1051|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K1051|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K233|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K233|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 3545 . AATG A 83.0 PASS DP=4239;AF=0.001651;SB=0;DP4=2121,2121,4,3;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aatgga/aga|NG1094R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aatgga/aga|NG1094R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aatgga/aga|NG276R|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aatgga/aga|NG276R|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3556 . TA T 104.0 PASS DP=4337;AF=0.001845;SB=0;DP4=2171,2170,4,4;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||aaa/|K1098|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K1098|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K280|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K280|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 3629 . G A 81.0 PASS DP=4401;AF=0.002272;SB=27;DP4=2198,2186,1,13;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtt/Att|V1122I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtt/Att|V1122I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtt/Att|V304I|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtt/Att|V304I|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3862 . T A 244.0 PASS DP=57;AF=0.157895;SB=0;DP4=24,23,5,5;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V1199|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V1199|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V381|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtA|V381|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 4534 . CT C 78.0 PASS DP=2839;AF=0.002113;SB=0;DP4=1420,1423,3,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tac/|Y1425|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tac/|Y1425|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tac/|Y607|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tac/|Y607|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 4747 . TA T 89.0 PASS DP=5698;AF=0.001404;SB=1;DP4=2924,2768,5,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||aca/|T1496|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aca/|T1496|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aca/|T678|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aca/|T678|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 5386 . T G 49314.0 PASS DP=5250;AF=0.929905;SB=0;DP4=2,1,2622,2618;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5644 . TACAAAATATCTAGTACAAC T 162.0 PASS DP=5796;AF=0.00207;SB=0;DP4=2970,2816,6,6;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||acaaaatatctagtacaacag/|TKYLVQQ1794|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acaaaatatctagtacaacag/|TKYLVQQ1794|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acaaaatatctagtacaacag/|TKYLVQQ976|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acaaaatatctagtacaacag/|TKYLVQQ976|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 5730 . C T 49314.0 PASS DP=7533;AF=0.953671;SB=0;DP4=1,1,3757,3757;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T1822I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T1822I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T1004I|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T1004I|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5743 . G C 2377.0 PASS DP=8027;AF=0.019933;SB=0;DP4=3922,3925,84,82;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5744 . T C 2354.0 PASS DP=8021;AF=0.019948;SB=1;DP4=3918,3924,87,83;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5777 . CAT C 88.0 PASS DP=7493;AF=0.001068;SB=0;DP4=3766,3761,4,4;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||ata/|I1839|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ata/|I1839|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ata/|I1021|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ata/|I1021|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 5799 . T C 94.0 PASS DP=6947;AF=0.001871;SB=0;DP4=3466,3454,7,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTg/tCg|L1845S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTg/tCg|L1845S|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTg/tCg|L1027S|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTg/tCg|L1027S|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6007 . T C 81.0 PASS DP=3112;AF=0.002892;SB=1;DP4=1557,1541,5,6;EFF=SYNONYMOUS_CODING(LOW|SILENT|ctT/ctC|L1914|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|ctT/ctC|L1914|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|ctT/ctC|L1096|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ctT/ctC|L1096|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6008 . G A 93.0 PASS DP=3222;AF=0.003104;SB=27;DP4=1619,1589,1,12;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gta/Ata|V1915I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gta/Ata|V1915I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gta/Ata|V1097I|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gta/Ata|V1097I|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6148 . T C 183.0 PASS DP=1904;AF=0.011555;SB=0;DP4=889,991,10,12;EFF=SYNONYMOUS_CODING(LOW|SILENT|ccT/ccC|P1961|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|ccT/ccC|P1961|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|ccT/ccC|P1143|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ccT/ccC|P1143|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6512 . AGTT A 42455.0 PASS DP=1205;AF=0.995021;SB=4;DP4=4,1,624,575;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6622 . GA G 86.0 PASS DP=2114;AF=0.002838;SB=0;DP4=1083,1025,3,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||acc/|T2121|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acc/|T2121|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acc/|T1303|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acc/|T1303|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 6653 . GTTAATAGTGTCCCTTGGGATACTATAGCTA G 229.0 PASS DP=2397;AF=0.005423;SB=0;DP4=1195,1195,7,6;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaatagtgtcccttgggatactatagctaat/gat|VNSVPWDTIAN2130D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaatagtgtcccttgggatactatagctaat/gat|VNSVPWDTIAN2130D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaatagtgtcccttgggatactatagctaat/gat|VNSVPWDTIAN1312D|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttaatagtgtcccttgggatactatagctaat/gat|VNSVPWDTIAN1312D|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6696 . C CT 553.0 PASS DP=2137;AF=0.013102;SB=0;DP4=1070,1069,14,14;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ctt/Tctt|L2146S?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L2146S?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L1328S?|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ctt/Tctt|L1328S?|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 7246 . GT G 129.0 PASS DP=3317;AF=0.003015;SB=0;DP4=1660,1659,5,5;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||ttg/|L2329|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L2329|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L1511|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttg/|L1511|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 7273 . GT G 70.0 PASS DP=3266;AF=0.001837;SB=0;DP4=1636,1633,3,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||ttc/|F2338|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttc/|F2338|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttc/|F1520|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttc/|F1520|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 7564 . CT C 110.0 PASS DP=6251;AF=0.0016;SB=0;DP4=3130,3125,5,5;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tat/|Y2435|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tat/|Y2435|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tat/|Y1617|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tat/|Y1617|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 7793 . CA C 74.0 PASS DP=3415;AF=0.001757;SB=0;DP4=1766,1655,3,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||aag/|K2511|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K2511|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K1693|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K1693|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 7889 . GT G 65.0 PASS DP=3735;AF=0.001606;SB=0;DP4=1921,1918,3,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||ttt/|F2543|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F2543|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F1725|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F1725|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 7926 . CAA C 73.0 PASS DP=3563;AF=0.001684;SB=0;DP4=1783,1782,3,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||aaa/|K2555|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K2555|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K1737|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K1737|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 8376 . CA C 222.0 PASS DP=3326;AF=0.00451;SB=0;DP4=1815,1496,9,6;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||agt/|S2706|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||agt/|S2706|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||agt/|S1888|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||agt/|S1888|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 8393 . G A 49314.0 PASS DP=3746;AF=0.941271;SB=6;DP4=0,2,2054,1674;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 9541 . CTGTTTAACACCAGTTTACTCATTCTTACCTGG C 128.0 PASS DP=3902;AF=0.002307;SB=0;DP4=2102,1791,5,4;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||acaccagtttactcattcttacctggtgtttat/|TPVYSFLPGVY3095|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acaccagtttactcattcttacctggtgtttat/|TPVYSFLPGVY3095|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acaccagtttactcattcttacctggtgtttat/|TPVYSFLPGVY332|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||acaccagtttactcattcttacctggtgtttat/|TPVYSFLPGVY332|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 10029 . C T 49314.0 PASS DP=6069;AF=0.90262;SB=6;DP4=1,4,3030,3014;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10449 . C A 49314.0 PASS DP=4350;AF=0.918621;SB=9;DP4=1,6,2112,2217;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10484 . T G 1272.0 PASS DP=2880;AF=0.025694;SB=8;DP4=1479,1319,35,44;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10501 . T G 109.0 PASS DP=3189;AF=0.003763;SB=12;DP4=1630,1529,16,6;EFF=SYNONYMOUS_CODING(LOW|SILENT|ggT/ggG|G3412|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|ggT/ggG|G3412|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|ggT/ggG|G149|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ggT/ggG|G149|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10541 . C A 919.0 PASS DP=3692;AF=0.016251;SB=3;DP4=1841,1777,32,38;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11087 . GA G 94.0 PASS DP=4902;AF=0.001632;SB=0;DP4=2534,2362,4,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||aat/|N3609|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aat/|N3609|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aat/|N40|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aat/|N40|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11104 . T C 108.0 PASS DP=4260;AF=0.002817;SB=0;DP4=2226,2016,7,6;EFF=SYNONYMOUS_CODING(LOW|SILENT|ccT/ccC|P3613|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|ccT/ccC|P3613|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|ccT/ccC|P44|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ccT/ccC|P44|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11133 . CT C 90.0 PASS DP=5562;AF=0.001438;SB=0;DP4=2863,2699,4,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttt/|F3624|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F3624|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F55|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ttt/|F55|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 11230 . G A 90.0 PASS DP=6865;AF=0.002039;SB=0;DP4=3404,3428,7,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|atG/atA|M3655I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|atG/atA|M3655I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|atG/atA|M86I|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|atG/atA|M86I|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11282 . AGTTTGTCTG A 49314.0 PASS DP=5673;AF=0.938128;SB=26;DP4=142,209,2600,2722;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF3674F|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ttgtctggtttt/ttt|LSGF105F|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 11368 . T C 82.0 PASS DP=8267;AF=0.001573;SB=0;DP4=4151,4094,9,9;EFF=SYNONYMOUS_CODING(LOW|SILENT|taT/taC|Y3701|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|taT/taC|Y3701|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|taT/taC|Y132|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|taT/taC|Y132|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11537 . A G 49314.0 PASS DP=7322;AF=0.937039;SB=0;DP4=0,0,3654,3660;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I3758V|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Att/Gtt|I189V|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 11654 . T C 138.0 PASS DP=4598;AF=0.003262;SB=0;DP4=2123,2454,7,9;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ttt/Ctt|F3797L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ttt/Ctt|F3797L|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ttt/Ctt|F228L|289|ORF1ab|protein_coding|CODING|YP_009725302.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ttt/Ctt|F228L|289|ORF1ab|protein_coding|CODING|YP_009742613.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 12505 . TA T 100.0 PASS DP=3285;AF=0.002435;SB=0;DP4=1609,1666,4,4;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aat/|N4082|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aat/|N4082|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aat/|N140|197|ORF1ab|protein_coding|CODING|YP_009725304.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aat/|N140|197|ORF1ab|protein_coding|CODING|YP_009742615.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.14) +NC_045512.2 13123 . TG T 163.0 PASS DP=6515;AF=0.002149;SB=0;DP4=3122,3391,7,7;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||gga/|G4288|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gga/|G4288|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gga/|G35|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gga/|G35|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.11) +NC_045512.2 13195 . T C 49314.0 PASS DP=7500;AF=0.936267;SB=0;DP4=6,5,3907,3571;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13225 . C CT 64.0 PASS DP=6148;AF=0.000976;SB=0;DP4=3364,2778,3,3;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||ggt/Tggt|G4322W?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggt/Tggt|G4322W?|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|CT|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggt/Tggt|G69W?|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||ggt/Tggt|G69W?|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|CT|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.11) +NC_045512.2 13282 . TA T 112.0 PASS DP=8378;AF=0.001194;SB=0;DP4=4184,4184,5,5;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||aaa/|K4340|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K4340|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K87|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K87|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.11) +NC_045512.2 13288 . AT A 151.0 PASS DP=8373;AF=0.001672;SB=0;DP4=4187,4188,7,7;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tgt/|C4343|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgt/|C4343|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgt/|C90|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tgt/|C90|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.11) +NC_045512.2 13394 . A G 95.0 PASS DP=7971;AF=0.001756;SB=11;DP4=3873,4044,17,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aaa/Gaa|K4377E|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aaa/Gaa|K4377E|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aaa/Gaa|K124E|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aaa/Gaa|K124E|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13459 . GT G 140.0 PASS DP=5692;AF=0.002108;SB=0;DP4=2599,3143,5,7;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||tta/|L4400|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L4400|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L8|12|ORF1ab|protein_coding|CODING|YP_009725312.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tta/|L8|931|ORF1ab|protein_coding|CODING|YP_009725307.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 13791 . A C 130.0 PASS DP=2538;AF=0.005122;SB=0;DP4=1382,1124,9,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caC|Q4509H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caC|Q117H|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 14408 . C T 49314.0 PASS DP=4480;AF=0.955134;SB=0;DP4=2,2,2335,2137;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P4715L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P323L|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15157 . CA C 66.0 PASS DP=3726;AF=0.00161;SB=1;DP4=1868,1850,4,2;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aaa/|K4966|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K574|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 15240 . C T 49314.0 PASS DP=3294;AF=0.945355;SB=0;DP4=0,0,1569,1719;EFF=SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N4992|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N600|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15521 . T A 1014.0 PASS DP=134;AF=0.268657;SB=0;DP4=46,49,19,20;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTt/tAt|F5086Y|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTt/tAt|F694Y|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15602 . G A 82.0 PASS DP=3712;AF=0.002694;SB=3;DP4=2009,1687,5,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cGc/cAc|R5113H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cGc/cAc|R721H|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15629 . G A 89.0 PASS DP=5890;AF=0.002037;SB=9;DP4=3122,2741,7,13;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tGt/tAt|C5122Y|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tGt/tAt|C730Y|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 16185 . T G 116.0 PASS DP=9416;AF=0.001805;SB=0;DP4=4587,4795,12,14;EFF=STOP_GAINED(HIGH|NONSENSE|taT/taG|Y5307*|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),STOP_GAINED(HIGH|NONSENSE|taT/taG|Y915*|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 16242 . T C 122.0 PASS DP=5776;AF=0.00277;SB=1;DP4=2946,2800,13,10;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V5326|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V2|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 16307 . T C 112.0 PASS DP=6737;AF=0.002227;SB=0;DP4=3356,3352,8,9;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTc/tCc|F5348S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTc/tCc|F24S|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 16837 . GA G 63.0 PASS DP=7007;AF=0.000999;SB=0;DP4=3624,3376,4,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aaa/|K5526|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aaa/|K202|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 17030 . ATGT A 322.0 PASS DP=7583;AF=0.002901;SB=0;DP4=3675,3917,11,11;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttgca/gca|VA5590A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttgca/gca|VA266A|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 17079 . G A 108.0 PASS DP=6397;AF=0.002501;SB=25;DP4=3065,3309,2,15;EFF=SYNONYMOUS_CODING(LOW|SILENT|caG/caA|Q5605|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),SYNONYMOUS_CODING(LOW|SILENT|caG/caA|Q281|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 17144 . G A 179.0 PASS DP=2796;AF=0.005722;SB=2;DP4=1401,1375,7,9;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cGc/cAc|R5627H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cGc/cAc|R303H|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 17452 . CCTG C 77.0 PASS DP=6606;AF=0.00106;SB=1;DP4=3359,3242,3,4;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||cctgca/cca|PA5730P|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C|INFO_REALIGN_3_PRIME),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||cctgca/cca|PA406P|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME) +NC_045512.2 18163 . A G 7591.0 PASS DP=220;AF=0.931818;SB=0;DP4=1,1,109,109;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I5967V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ata/Gta|I42V|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18687 . CT C 114.0 PASS DP=4125;AF=0.002182;SB=0;DP4=2089,2055,5,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tcc/|S6143|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||tcc/|S218|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 19037 . G A 80.0 PASS DP=7193;AF=0.001668;SB=0;DP4=3582,3589,7,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGt/gAt|G6258D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGt/gAt|G333D|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 19077 . A T 1473.0 PASS DP=7640;AF=0.012958;SB=1;DP4=3760,3759,60,54;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtA/gtT|V6271|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|gtA/gtT|V346|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 19600 . A T 82.0 PASS DP=4246;AF=0.002355;SB=35;DP4=2220,2005,13,0;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aac/Tac|N6446Y|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aac/Tac|N521Y|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 19983 . C T 197.0 PASS DP=5284;AF=0.004164;SB=1;DP4=2624,2616,16,18;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtC/gtT|V6573|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|gtC/gtT|V121|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 20327 . T C 82.0 PASS DP=5617;AF=0.001958;SB=3;DP4=2781,2794,10,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTt/gCt|V6688A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gTt/gCt|V236A|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 20407 . TTTG T 69.0 PASS DP=5149;AF=0.001165;SB=0;DP4=2508,2636,3,3;INDEL;HRUN=4;EFF=STOP_GAINED+CODON_CHANGE_PLUS_CODON_DELETION(HIGH||tttgaa/taa|FE6715*|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),STOP_GAINED+CODON_CHANGE_PLUS_CODON_DELETION(HIGH||tttgaa/taa|FE263*|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 20464 . G A 123.0 PASS DP=5066;AF=0.002961;SB=42;DP4=2483,2563,0,15;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gat/Aat|D6734N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gat/Aat|D282N|345|ORF1ab|protein_coding|CODING|YP_009725310.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 21066 . TA T 69.0 PASS DP=3351;AF=0.001791;SB=0;DP4=1807,1538,3,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aat/|N6936|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aat/|N138|297|ORF1ab|protein_coding|CODING|YP_009725311.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.04) +NC_045512.2 21236 . T C 86.0 PASS DP=3689;AF=0.002711;SB=0;DP4=1836,1833,6,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTt/tCt|F6991S|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tTt/tCt|F193S|297|ORF1ab|protein_coding|CODING|YP_009725311.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 21440 . C T 93.0 PASS DP=2295;AF=0.003922;SB=1;DP4=1147,1132,6,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCt/tTt|S7059F|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCt/tTt|S261F|297|ORF1ab|protein_coding|CODING|YP_009725311.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 21634 . AC A 67.0 PASS DP=5941;AF=0.001178;SB=1;DP4=3001,2938,3,4;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||cct/|P26|1273|S|protein_coding|CODING|GU280_gp02|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 21736 . CT C 194.0 PASS DP=4908;AF=0.002852;SB=0;DP4=2448,2448,7,7;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||tcc/|S60|1273|S|protein_coding|CODING|GU280_gp02|1|C|INFO_REALIGN_3_PRIME) +NC_045512.2 21740 . TCCAATGTTACTTGGTTCCATGCTATACATGTCTCTGGGA T 782.0 PASS DP=4911;AF=0.008349;SB=0;DP4=2434,2436,20,21;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gttacttggttccatgctatacatgtctctgggaccaatggt/ggt|VTWFHAIHVSGTNG62G|1273|S|protein_coding|CODING|GU280_gp02|1|T|INFO_REALIGN_3_PRIME) +NC_045512.2 21762 . C T 49314.0 PASS DP=4470;AF=0.948993;SB=0;DP4=0,0,2204,2216;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A67V|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21764 . ATACATG A 49314.0 PASS DP=4328;AF=0.986599;SB=4;DP4=26,34,2134,2136;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||atacatgtc/atc|IHV68I|1273|S|protein_coding|CODING|GU280_gp02|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 21846 . C T 49314.0 PASS DP=3700;AF=0.96027;SB=0;DP4=1,2,1800,1895;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T95I|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21986 . GGTGTTTATT G 49314.0 PASS DP=2044;AF=0.988258;SB=2;DP4=31,34,1054,966;INDEL;HRUN=3;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggtgtttattac/gac|GVYY142D|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 22193 . AATT A 49314.0 PASS DP=2191;AF=0.915107;SB=72;DP4=284,464,993,1012;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattta/ata|NL211I|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22204 . T TGAGCCAGAA 49314.0 PASS DP=1833;AF=0.798691;SB=3;DP4=168,169,695,769;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGAAGAt|D215EPED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22204 . T TGAGACAGAA 92.0 PASS DP=1833;AF=0.003273;SB=1;DP4=168,169,2,4;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGACAGAAGAt|D215ETED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGACAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22207 . T G 80.0 PASS DP=2316;AF=0.006908;SB=0;DP4=1113,1178,10,11;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaT/gaG|D215E|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 22578 . G A 49314.0 PASS DP=1913;AF=0.959749;SB=0;DP4=0,0,950,956;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGt/gAt|G339D|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22583 . G GT 119.0 PASS DP=1903;AF=0.004204;SB=0;DP4=948,947,4,4;INDEL;HRUN=5;EFF=FRAME_SHIFT+STOP_GAINED(HIGH||aac/Taac|N343*?|1273|S|protein_coding|CODING|GU280_gp02|1|GT|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 22673 . T C 30956.0 PASS DP=888;AF=0.942568;SB=7;DP4=2,0,376,508;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tcc/Ccc|S371P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22674 . C T 29554.0 PASS DP=882;AF=0.905896;SB=0;DP4=0,1,375,503;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S371F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22679 . T C 33009.0 PASS DP=949;AF=0.929399;SB=0;DP4=0,0,406,541;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Cca|S373P|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 22685 . TC T 107.0 PASS DP=960;AF=0.00625;SB=1;DP4=406,548,3,3;INDEL;HRUN=2;EFF=FRAME_SHIFT(HIGH||tcc/|S375|1273|S|protein_coding|CODING|GU280_gp02|1|T|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 22686 . C T 34483.0 PASS DP=960;AF=0.947917;SB=0;DP4=0,1,406,547;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCc/tTc|S375F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22992 . G A 38681.0 PASS DP=1133;AF=0.945278;SB=0;DP4=0,0,607,523;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGc/aAc|S477N|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22995 . C A 39179.0 PASS DP=1143;AF=0.929134;SB=0;DP4=0,0,611,530;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T478K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23013 . A C 49314.0 PASS DP=1658;AF=0.947527;SB=0;DP4=1,0,886,769;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gCa|E484A|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23040 . A G 49314.0 PASS DP=2128;AF=0.949248;SB=0;DP4=0,0,1121,1006;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q493R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23048 . G A 49314.0 PASS DP=2551;AF=0.969816;SB=0;DP4=0,0,1342,1205;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G496S|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23055 . A G 49314.0 PASS DP=2628;AF=0.927321;SB=0;DP4=1,1,1378,1247;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q498R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23063 . A T 49314.0 PASS DP=3081;AF=0.964946;SB=3;DP4=0,1,1618,1459;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aat/Tat|N501Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23075 . T C 49314.0 PASS DP=3182;AF=0.941546;SB=11;DP4=5,0,1660,1513;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y505H|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23143 . TA T 88.0 PASS DP=4536;AF=0.001764;SB=0;DP4=2263,2263,4,4;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aag/|K529|1273|S|protein_coding|CODING|GU280_gp02|1|T|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 23202 . C A 49314.0 PASS DP=4441;AF=0.954965;SB=0;DP4=0,1,2210,2220;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T547K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23230 . CA C 66.0 PASS DP=3770;AF=0.001592;SB=0;DP4=1862,1927,3,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aag/|K558|1273|S|protein_coding|CODING|GU280_gp02|1|C|INFO_REALIGN_3_PRIME);LOF=(S|GU280_gp02|1|1.00) +NC_045512.2 23403 . A G 49314.0 PASS DP=7121;AF=0.935262;SB=6;DP4=2,0,3550,3562;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D614G|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23525 . C T 49314.0 PASS DP=6027;AF=0.953542;SB=3;DP4=0,2,2915,3101;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cat/Tat|H655Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23599 . T G 49314.0 PASS DP=2570;AF=0.938521;SB=0;DP4=1,1,1184,1381;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaG|N679K|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23604 . C A 49314.0 PASS DP=2144;AF=0.944963;SB=0;DP4=0,1,969,1169;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cAt|P681H|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23854 . C A 110.0 PASS DP=5;AF=0.6;SB=0;DP4=0,0,3,2;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaC/aaA|N764K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23948 . G T 35131.0 PASS DP=1010;AF=0.923762;SB=0;DP4=1,1,476,531;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gat/Tat|D796Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24130 . C A 49314.0 PASS DP=1793;AF=0.929727;SB=0;DP4=0,0,842,944;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaC/aaA|N856K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24223 . C T 88.0 PASS DP=2872;AF=0.003482;SB=1;DP4=1522,1337,5,6;EFF=SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T887|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24340 . A T 84.0 PASS DP=5032;AF=0.002583;SB=1;DP4=2503,2505,8,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caT|Q926H|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24424 . A T 49314.0 PASS DP=4589;AF=0.958815;SB=0;DP4=3,3,2286,2292;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caT|Q954H|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24469 . T A 49314.0 PASS DP=5454;AF=0.938761;SB=0;DP4=2,2,2755,2690;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N969K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24503 . C T 49314.0 PASS DP=5783;AF=0.946049;SB=0;DP4=7,7,2842,2919;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L981F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24942 . A T 100.0 PASS DP=2710;AF=0.004428;SB=1;DP4=1346,1348,8,6;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gTt|D1127V|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25000 . C T 49314.0 PASS DP=2454;AF=0.92991;SB=0;DP4=1,1,1223,1223;EFF=SYNONYMOUS_CODING(LOW|SILENT|gaC/gaT|D1146|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25086 . C T 84.0 PASS DP=2664;AF=0.003378;SB=9;DP4=1344,1302,8,2;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|tCa/tTa|S1175L|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25584 . C T 49314.0 PASS DP=3174;AF=0.920605;SB=2;DP4=1,2,1583,1580;EFF=SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T64|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 25673 . T C 84.0 PASS DP=3544;AF=0.003104;SB=3;DP4=1786,1735,6,9;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cTt/cCt|L94P|275|ORF3a|protein_coding|CODING|GU280_gp03|1|C) +NC_045512.2 25704 . T C 111.0 PASS DP=3591;AF=0.00362;SB=0;DP4=1821,1750,8,8;EFF=SYNONYMOUS_CODING(LOW|SILENT|ccT/ccC|P104|275|ORF3a|protein_coding|CODING|GU280_gp03|1|C) +NC_045512.2 25982 . TA T 83.0 PASS DP=4292;AF=0.001631;SB=0;DP4=2081,2211,3,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||aaa/|K198|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T|INFO_REALIGN_3_PRIME);LOF=(ORF3a|GU280_gp03|1|1.00) +NC_045512.2 26194 . A T 136.0 PASS DP=7640;AF=0.002618;SB=2;DP4=3792,3781,13,16;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Acg/Tcg|T268S|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 26270 . C T 49314.0 PASS DP=5826;AF=0.930827;SB=0;DP4=5,5,2700,3105;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aTa|T9I|75|E|protein_coding|CODING|GU280_gp04|1|T) +NC_045512.2 26325 . G A 175.0 PASS DP=4572;AF=0.003937;SB=44;DP4=2012,2541,0,18;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttG/ttA|L27|75|E|protein_coding|CODING|GU280_gp04|1|A) +NC_045512.2 26440 . A T 152.0 PASS DP=3155;AF=0.004437;SB=63;DP4=1554,1575,22,0;AmpliconBias;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aat/Tat|N66Y|75|E|protein_coding|CODING|GU280_gp04|1|T) +NC_045512.2 26530 . A G 49314.0 PASS DP=2453;AF=0.927436;SB=0;DP4=0,1,1199,1250;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D3G|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26554 . A T 106.0 PASS DP=2042;AF=0.004897;SB=19;DP4=976,1053,11,2;AmpliconBias;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gTa|E11V|222|M|protein_coding|CODING|GU280_gp05|1|T) +NC_045512.2 26573 . TG T 103.0 PASS DP=1124;AF=0.005338;SB=0;DP4=546,572,3,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||gaa/|E18|222|M|protein_coding|CODING|GU280_gp05|1|T);LOF=(M|GU280_gp05|1|1.00) +NC_045512.2 26577 . C G 38800.0 PASS DP=1112;AF=0.946043;SB=0;DP4=3,4,540,563;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Caa/Gaa|Q19E|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 26709 . G A 17270.0 PASS DP=502;AF=0.916335;SB=0;DP4=0,1,250,249;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A63T|222|M|protein_coding|CODING|GU280_gp05|1|A) +NC_045512.2 27259 . A C 49314.0 PASS DP=3537;AF=0.949109;SB=2;DP4=1,2,1827,1706;EFF=SYNONYMOUS_CODING(LOW|SILENT|Agg/Cgg|R20|61|ORF6|protein_coding|CODING|GU280_gp06|1|C) +NC_045512.2 27407 . T C 81.0 PASS DP=4405;AF=0.00227;SB=1;DP4=2192,2193,6,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cTt/cCt|L5P|121|ORF7a|protein_coding|CODING|GU280_gp07|1|C) +NC_045512.2 27605 . TA T 121.0 PASS DP=2244;AF=0.003565;SB=0;DP4=1117,1119,4,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||aaa/|K72|121|ORF7a|protein_coding|CODING|GU280_gp07|1|T|INFO_REALIGN_3_PRIME);LOF=(ORF7a|GU280_gp07|1|1.00) +NC_045512.2 27792 . T C 100.0 PASS DP=4987;AF=0.002406;SB=3;DP4=2484,2478,7,10;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ttt/Ctt|F13L|43|ORF7b|protein_coding|CODING|GU280_gp08|1|C) +NC_045512.2 27807 . C T 49314.0 PASS DP=5350;AF=0.951963;SB=3;DP4=2,0,2681,2656;EFF=SYNONYMOUS_CODING(LOW|SILENT|Cta/Tta|L18|43|ORF7b|protein_coding|CODING|GU280_gp08|1|T) +NC_045512.2 28253 . CA C 64.0 PASS DP=6499;AF=0.000923;SB=0;DP4=3282,3212,3,3;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||atc/|I121|121|ORF8|protein_coding|CODING|GU280_gp09|1|C) +NC_045512.2 28271 . A T 49314.0 PASS DP=6980;AF=0.962034;SB=9;DP4=1,6,3483,3482 +NC_045512.2 28311 . C T 49314.0 PASS DP=6971;AF=0.89442;SB=17;DP4=8,22,3378,3544;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cTc|P13L|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28361 . GGAGAACGCA G 49314.0 PASS DP=5815;AF=0.830095;SB=4;DP4=461,528,2325,2502;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggagaacgcagt/ggt|GERS30G|419|N|protein_coding|CODING|GU280_gp10|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 28363 . AGAACGCAGT A 265.0 PASS DP=4935;AF=0.005876;SB=52;DP4=2373,2555,26,3;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gaacgcagtggg/ggg|ERSG31G|419|N|protein_coding|CODING|GU280_gp10|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 28628 . G T 245.0 PASS DP=3501;AF=0.005998;SB=11;DP4=1786,1689,17,7;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Tct|A119S|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28717 . C T 552.0 PASS DP=4586;AF=0.010031;SB=0;DP4=2269,2256,26,26;EFF=SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T148|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28881 . G A 49314.0 PASS DP=2575;AF=0.894369;SB=0;DP4=0,0,1255,1252;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGg/aAg|R203K|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28881 . G T 49314.0 PASS DP=2575;AF=0.021748;SB=0;DP4=0,0,32,35;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGg/aTg|R203M|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28882 . G A 49314.0 PASS DP=2567;AF=0.883522;SB=2;DP4=29,34,1254,1231;EFF=SYNONYMOUS_CODING(LOW|SILENT|agG/agA|R203|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28883 . G C 49314.0 PASS DP=2570;AF=0.921012;SB=2;DP4=29,34,1254,1250;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gga/Cga|G204R|419|N|protein_coding|CODING|GU280_gp10|1|C) +NC_045512.2 28936 . G T 149.0 PASS DP=2663;AF=0.004882;SB=571;DP4=1178,1294,188,0;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|ttG/ttT|L221F|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28987 . CCAA C 81.0 PASS DP=3271;AF=0.001834;SB=0;DP4=1645,1671,3,3;INDEL;HRUN=2;EFF=CODON_DELETION(MODERATE||caa/|Q242|419|N|protein_coding|CODING|GU280_gp10|1|C|INFO_REALIGN_3_PRIME) +NC_045512.2 29127 . AT A 79.0 PASS DP=2633;AF=0.002279;SB=0;DP4=1260,1372,3,3;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||ttt/|F286|419|N|protein_coding|CODING|GU280_gp10|1|A|INFO_REALIGN_3_PRIME);LOF=(N|GU280_gp10|1|1.00) +NC_045512.2 29377 . TA T 174.0 PASS DP=3982;AF=0.003265;SB=1;DP4=1986,1989,7,6;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||aag/|K370|419|N|protein_coding|CODING|GU280_gp10|1|T|INFO_REALIGN_3_PRIME);LOF=(N|GU280_gp10|1|1.00) +NC_045512.2 29562 . G A 201.0 PASS DP=1166;AF=0.012007;SB=0;DP4=586,561,7,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gGc/gAc|G2D|38|ORF10|protein_coding|CODING|GU280_gp11|1|A) diff --git a/example_data/example_mave_data/input/sample-11.vcf b/example_data/example_mave_data/input/sample-11.vcf new file mode 100644 index 0000000..90fd6f6 --- /dev/null +++ b/example_data/example_mave_data/input/sample-11.vcf @@ -0,0 +1,30 @@ +##fileformat=VCFv4.0 +##FILTER= +##fileDate=20240114 +##source=lofreq call --verbose --ref reference.fa --call-indels --min-cov 5 --max-depth 1000000 --min-bq 30 --min-alt-bq 30 --min-mq 20 --max-mq 255 --min-jq 0 --min-alt-jq 0 --def-alt-jq 0 --sig 0.0005 --bonf dynamic --no-default-filter --no-default-filter -r NC_045512.2:1-7475 -o /data/jwd05e/main/066/348/66348166/tmp/lofreq2_call_parallel2hkqokkg/0.vcf.gz reads.bam +##reference=reference.fa +##INFO= +##INFO= --min-bq among all bases at the site"> +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##INFO= +##bcftools_annotateVersion=1.10.2+htslib-1.10.2 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites -AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 21:54:25 2024 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites +AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 21:55:39 2024 +##SnpEffVersion="4.5covid19 (build 2020-04-15 22:26), by Pablo Cingolani" +##SnpEffCmd="SnpEff -i vcf -o vcf -formatEff -classic -no-downstream -no-intergenic -no-upstream -stats /data/jwd05e/main/066/348/66348346/outputs/dataset_3109d163-b480-42e6-a09b-98d2487b79fc.dat NC_045512.2 /data/dnb09/galaxy_db/files/0/5/7/dataset_0573f2f9-0002-4ea7-8a3c-e2aff7b2f927.dat " +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +NC_045512.2 16239 . T TG 44.0 PASS DP=149;AF=0.013423;SB=0;DP4=96,92,1,1;INDEL;HRUN=1;EFF=FRAME_SHIFT(HIGH||gtt/gGtt|V5326G?|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|TG|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||gtt/gGtt|V2G?|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|TG|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.04) +NC_045512.2 16410 . A T 70.0 PASS DP=183;AF=0.021858;SB=0;DP4=80,97,3,3;EFF=SYNONYMOUS_CODING(LOW|SILENT|acA/acT|T5382|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|acA/acT|T58|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 27807 . C T 14238.0 PASS DP=410;AF=0.926829;SB=3;DP4=0,1,206,202;EFF=SYNONYMOUS_CODING(LOW|SILENT|Cta/Tta|L18|43|ORF7b|protein_coding|CODING|GU280_gp08|1|T) diff --git a/example_data/example_mave_data/input/sample-12.vcf b/example_data/example_mave_data/input/sample-12.vcf new file mode 100644 index 0000000..4fa453e --- /dev/null +++ b/example_data/example_mave_data/input/sample-12.vcf @@ -0,0 +1,94 @@ +##fileformat=VCFv4.0 +##FILTER= +##fileDate=20240114 +##source=lofreq call --verbose --ref reference.fa --call-indels --min-cov 5 --max-depth 1000000 --min-bq 30 --min-alt-bq 30 --min-mq 20 --max-mq 255 --min-jq 0 --min-alt-jq 0 --def-alt-jq 0 --sig 0.0005 --bonf dynamic --no-default-filter --no-default-filter -r NC_045512.2:1-7475 -o /data/jwd05e/main/066/348/66348167/tmp/lofreq2_call_parallel3xcmz_fx/0.vcf.gz reads.bam +##reference=reference.fa +##INFO= +##INFO= --min-bq among all bases at the site"> +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##INFO= +##bcftools_annotateVersion=1.10.2+htslib-1.10.2 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites -AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 22:16:41 2024 +##bcftools_annotateCommand=annotate --columns QUAL,INFO --annotations annotations.vcf.gz --mark-sites +AmpliconBias --output-type v --threads 1 input.vcf.gz; Date=Sun Jan 14 22:17:41 2024 +##SnpEffVersion="4.5covid19 (build 2020-04-15 22:26), by Pablo Cingolani" +##SnpEffCmd="SnpEff -i vcf -o vcf -formatEff -classic -no-downstream -no-intergenic -no-upstream -stats /data/jwd02f/main/066/348/66348347/outputs/dataset_65b7fc87-8025-44cf-8d33-7cf59de0b914.dat NC_045512.2 /data/dnb09/galaxy_db/files/7/6/4/dataset_76410c3b-51f4-49a0-87e0-50004fc168bd.dat " +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +NC_045512.2 241 . C T 150.0 PASS DP=5;AF=0.8;SB=0;DP4=0,0,3,2 +NC_045512.2 2556 . A G 6467.0 PASS DP=188;AF=0.925532;SB=0;DP4=0,0,97,91;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q764R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q764R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q584R|637|ORF1ab|protein_coding|CODING|YP_009725298.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q584R|637|ORF1ab|protein_coding|CODING|YP_009742609.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 3037 . C T 225.0 PASS DP=8;AF=0.75;SB=0;DP4=0,0,4,4;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F924|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ttC/ttT|F106|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 4975 . G A 94.0 PASS DP=1911;AF=0.00471;SB=18;DP4=862,1036,1,10;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtG/gtA|V1570|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),SYNONYMOUS_CODING(LOW|SILENT|gtG/gtA|V1570|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),SYNONYMOUS_CODING(LOW|SILENT|gtG/gtA|V752|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtG/gtA|V752|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5308 . A G 648.0 PASS DP=597;AF=0.051926;SB=0;DP4=299,264,17,16;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttA/ttG|L1681|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|ttA/ttG|L1681|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|ttA/ttG|L863|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ttA/ttG|L863|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5386 . T G 28749.0 PASS DP=857;AF=0.907818;SB=6;DP4=0,3,427,424;EFF=SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A1707|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gcT/gcG|A889|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5743 . G C 124.0 PASS DP=500;AF=0.016;SB=0;DP4=246,245,4,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1826D|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gaG/gaC|E1008D|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5744 . T C 121.0 PASS DP=498;AF=0.016064;SB=0;DP4=244,245,4,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1827H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y1009H|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 5924 . G A 10749.0 PASS DP=322;AF=0.919255;SB=0;DP4=0,0,160,161;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtt/Att|V1887I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtt/Att|V1887I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtt/Att|V1069I|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gtt/Att|V1069I|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6076 . T C 1414.0 PASS DP=226;AF=0.225664;SB=0;DP4=85,85,28,28;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttT/ttC|F1937|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|ttT/ttC|F1937|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|ttT/ttC|F1119|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|ttT/ttC|F1119|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 6512 . AGTT A 253.0 PASS DP=8;AF=0.875;SB=0;DP4=1,0,3,4;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL2083I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||agttta/ata|SL1265I|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 8393 . G A 8417.0 PASS DP=238;AF=0.945378;SB=0;DP4=0,0,122,115;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A2710T|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009725299.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A1892T|1944|ORF1ab|protein_coding|CODING|YP_009742610.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10029 . C T 9530.0 PASS DP=297;AF=0.875421;SB=0;DP4=0,0,148,147;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T3255I|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009725300.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCc/aTc|T492I|499|ORF1ab|protein_coding|CODING|YP_009742611.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10449 . C A 443.0 PASS DP=12;AF=1;SB=0;DP4=0,0,7,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P3395H|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cAc|P132H|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10484 . T G 284.0 PASS DP=45;AF=0.222222;SB=0;DP4=19,16,5,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S3407A|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tca/Gca|S144A|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 10541 . C A 148.0 PASS DP=63;AF=0.095238;SB=0;DP4=29,28,3,3;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H3426N|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009725301.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Cac/Aac|H163N|305|ORF1ab|protein_coding|CODING|YP_009742612.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 12285 . A G 106.0 PASS DP=670;AF=0.010448;SB=0;DP4=310,352,3,4;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q4007R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q4007R|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q65R|197|ORF1ab|protein_coding|CODING|YP_009725304.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q65R|197|ORF1ab|protein_coding|CODING|YP_009742615.1|1|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13195 . T C 32498.0 PASS DP=944;AF=0.934322;SB=0;DP4=1,1,512,430;EFF=SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|7096|ORF1ab|protein_coding|CODING|GU280_gp01|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V4310|4405|ORF1ab|protein_coding|CODING|GU280_gp01.2|1|C),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009725306.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON),SYNONYMOUS_CODING(LOW|SILENT|gtT/gtC|V57|138|ORF1ab|protein_coding|CODING|YP_009742617.1|1|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 13791 . A C 114.0 PASS DP=29;AF=0.172414;SB=1;DP4=13,11,2,3;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caC|Q4509H|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|C),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caC|Q117H|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|C|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 14408 . C T 24591.0 PASS DP=691;AF=0.949349;SB=0;DP4=0,0,357,333;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P4715L|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCt/cTt|P323L|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15017 . C T 781.0 PASS DP=341;AF=0.096774;SB=0;DP4=162,140,19,18;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCa/gTa|A4918V|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCa/gTa|A526V|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15240 . C T 18594.0 PASS DP=529;AF=0.931947;SB=0;DP4=0,0,257,272;EFF=SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N4992|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T),SYNONYMOUS_CODING(LOW|SILENT|aaC/aaT|N600|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|T|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 15884 . A G 75.0 PASS DP=2661;AF=0.003006;SB=0;DP4=1241,1405,5,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q5207R|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|G),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q815R|931|ORF1ab|protein_coding|CODING|YP_009725307.1|2|G|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 17572 . G A 11316.0 PASS DP=5897;AF=0.084111;SB=0;DP4=2672,2667,271,275;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A5770T|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|A),NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gct/Act|A446T|600|ORF1ab|protein_coding|CODING|YP_009725308.1|1|A|WARNING_TRANSCRIPT_NO_START_CODON) +NC_045512.2 18530 . TA T 57.0 PASS DP=45;AF=0.044444;SB=0;DP4=21,22,1,1;INDEL;HRUN=3;EFF=FRAME_SHIFT(HIGH||aag/|K6090|7096|ORF1ab|protein_coding|CODING|GU280_gp01|2|T|INFO_REALIGN_3_PRIME),FRAME_SHIFT(HIGH||aag/|K165|526|ORF1ab|protein_coding|CODING|YP_009725309.1|1|T|WARNING_TRANSCRIPT_NO_START_CODON&INFO_REALIGN_3_PRIME);LOF=(ORF1ab|GU280_gp01|28|0.07) +NC_045512.2 21762 . C T 24686.0 PASS DP=729;AF=0.961591;SB=0;DP4=0,0,365,362;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gCt/gTt|A67V|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 21764 . ATACATG A 24598.0 PASS DP=709;AF=0.997179;SB=6;DP4=0,2,355,352;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||atacatgtc/atc|IHV68I|1273|S|protein_coding|CODING|GU280_gp02|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 21846 . C T 20228.0 PASS DP=564;AF=0.948582;SB=0;DP4=0,1,275,288;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCt/aTt|T95I|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 22193 . AATT A 364.0 PASS DP=10;AF=1;SB=0;DP4=0,0,6,4;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||aattta/ata|NL211I|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22204 . T TGAGCCAGAA 353.0 PASS DP=10;AF=1;SB=0;DP4=0,0,6,4;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_INSERTION(MODERATE||gat/gaGCCAGAAGAt|D215EPED|1273|S|protein_coding|CODING|GU280_gp02|1|TGAGCCAGAA|INFO_REALIGN_3_PRIME) +NC_045512.2 22992 . G A 1673.0 PASS DP=48;AF=0.958333;SB=0;DP4=0,0,25,23;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGc/aAc|S477N|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 22995 . C A 1512.0 PASS DP=48;AF=0.854167;SB=0;DP4=0,0,25,23;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T478K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23013 . A C 2501.0 PASS DP=68;AF=0.970588;SB=0;DP4=0,0,38,30;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAa/gCa|E484A|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23040 . A G 3890.0 PASS DP=111;AF=0.936937;SB=0;DP4=0,0,59,51;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q493R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23048 . G A 4778.0 PASS DP=132;AF=0.954545;SB=0;DP4=0,0,72,60;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ggt/Agt|G496S|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 23055 . A G 4712.0 PASS DP=135;AF=0.948148;SB=0;DP4=0,0,73,62;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q498R|1273|S|protein_coding|CODING|GU280_gp02|1|G) +NC_045512.2 23063 . A T 5465.0 PASS DP=152;AF=0.953947;SB=0;DP4=0,0,81,71;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aat/Tat|N501Y|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 23075 . T C 5263.0 PASS DP=152;AF=0.940789;SB=0;DP4=0,0,80,72;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Tac/Cac|Y505H|1273|S|protein_coding|CODING|GU280_gp02|1|C) +NC_045512.2 23202 . C A 8294.0 PASS DP=233;AF=0.944206;SB=0;DP4=0,0,115,118;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aAa|T547K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24424 . A T 4826.0 PASS DP=131;AF=0.969466;SB=0;DP4=0,0,65,66;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|caA/caT|Q954H|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 24469 . T A 48621.0 PASS DP=1405;AF=0.932384;SB=0;DP4=2,1,740,660;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aaT/aaA|N969K|1273|S|protein_coding|CODING|GU280_gp02|1|A) +NC_045512.2 24503 . C T 28469.0 PASS DP=1943;AF=0.471951;SB=0;DP4=497,464,502,475;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Ctt/Ttt|L981F|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25000 . C T 158.0 PASS DP=6;AF=1;SB=0;DP4=0,0,3,3;EFF=SYNONYMOUS_CODING(LOW|SILENT|gaC/gaT|D1146|1273|S|protein_coding|CODING|GU280_gp02|1|T) +NC_045512.2 25584 . C T 17820.0 PASS DP=531;AF=0.898305;SB=0;DP4=0,0,266,261;EFF=SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T64|275|ORF3a|protein_coding|CODING|GU280_gp03|1|T) +NC_045512.2 26126 . A G 140.0 PASS DP=3705;AF=0.003779;SB=0;DP4=1843,1841,8,8;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cAa/cGa|Q245R|275|ORF3a|protein_coding|CODING|GU280_gp03|1|G) +NC_045512.2 26270 . C T 49314.0 PASS DP=3496;AF=0.884439;SB=0;DP4=103,113,1558,1714;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aCa/aTa|T9I|75|E|protein_coding|CODING|GU280_gp04|1|T) +NC_045512.2 26325 . G A 118.0 PASS DP=2367;AF=0.004647;SB=33;DP4=1061,1290,0,13;EFF=SYNONYMOUS_CODING(LOW|SILENT|ttG/ttA|L27|75|E|protein_coding|CODING|GU280_gp04|1|A) +NC_045512.2 26530 . A G 338.0 PASS DP=10;AF=0.9;SB=0;DP4=0,0,5,5;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|gAt/gGt|D3G|222|M|protein_coding|CODING|GU280_gp05|1|G) +NC_045512.2 27259 . A C 1244.0 PASS DP=38;AF=0.894737;SB=0;DP4=0,0,20,18;EFF=SYNONYMOUS_CODING(LOW|SILENT|Agg/Cgg|R20|61|ORF6|protein_coding|CODING|GU280_gp06|1|C) +NC_045512.2 27807 . C T 40609.0 PASS DP=1139;AF=0.954346;SB=0;DP4=0,0,570,567;EFF=SYNONYMOUS_CODING(LOW|SILENT|Cta/Tta|L18|43|ORF7b|protein_coding|CODING|GU280_gp08|1|T) +NC_045512.2 28214 . CT C 56.0 PASS DP=5410;AF=0.001109;SB=0;DP4=2720,2730,3,3;INDEL;HRUN=5;EFF=FRAME_SHIFT(HIGH||tta/|L109|121|ORF8|protein_coding|CODING|GU280_gp09|1|C|INFO_REALIGN_3_PRIME);LOF=(ORF8|GU280_gp09|1|1.00) +NC_045512.2 28254 . A C 287.0 PASS DP=6112;AF=0.005072;SB=0;DP4=3029,3036,19,20;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Atc/Ctc|I121L|121|ORF8|protein_coding|CODING|GU280_gp09|1|C) +NC_045512.2 28265 . C T 103.0 PASS DP=8103;AF=0.001975;SB=36;DP4=4026,4047,18,2 +NC_045512.2 28271 . A T 49314.0 PASS DP=8604;AF=0.953045;SB=9;DP4=1,6,4293,4295 +NC_045512.2 28311 . C T 49314.0 PASS DP=8554;AF=0.873977;SB=17;DP4=5,17,4156,4338;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cCc/cTc|P13L|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28361 . GGAGAACGCA G 49314.0 PASS DP=7473;AF=0.825238;SB=2;DP4=621,689,2977,3190;INDEL;HRUN=2;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||ggagaacgcagt/ggt|GERS30G|419|N|protein_coding|CODING|GU280_gp10|1|G|INFO_REALIGN_3_PRIME) +NC_045512.2 28363 . AGAACGCAGT A 431.0 PASS DP=6305;AF=0.006979;SB=120;DP4=3030,3257,43,1;INDEL;HRUN=1;EFF=CODON_CHANGE_PLUS_CODON_DELETION(MODERATE||gaacgcagtggg/ggg|ERSG31G|419|N|protein_coding|CODING|GU280_gp10|1|A|INFO_REALIGN_3_PRIME) +NC_045512.2 28383 . CA C 81.0 PASS DP=7200;AF=0.001111;SB=0;DP4=3515,3698,4,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||aaa/|K38|419|N|protein_coding|CODING|GU280_gp10|1|C|INFO_REALIGN_3_PRIME);LOF=(N|GU280_gp10|1|1.00) +NC_045512.2 28388 . C T 82.0 PASS DP=7347;AF=0.001769;SB=24;DP4=3557,3766,15,3;EFF=STOP_GAINED(HIGH|NONSENSE|Caa/Taa|Q39*|419|N|protein_coding|CODING|GU280_gp10|1|T) +NC_045512.2 28776 . CA C 114.0 PASS DP=4033;AF=0.002232;SB=0;DP4=1981,2046,4,5;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||aaa/|K169|419|N|protein_coding|CODING|GU280_gp10|1|C|INFO_REALIGN_3_PRIME);LOF=(N|GU280_gp10|1|1.00) +NC_045512.2 28845 . G A 180.0 PASS DP=2283;AF=0.007008;SB=1;DP4=1084,1179,8,11;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|cGc/cAc|R191H|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28881 . G A 49314.0 PASS DP=1608;AF=0.93408;SB=0;DP4=1,1,784,819;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|aGg/aAg|R203K|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28882 . G A 49314.0 PASS DP=1601;AF=0.891318;SB=2;DP4=1,3,779,804;EFF=SYNONYMOUS_CODING(LOW|SILENT|agG/agA|R203|419|N|protein_coding|CODING|GU280_gp10|1|A) +NC_045512.2 28883 . G C 49314.0 PASS DP=1603;AF=0.928259;SB=0;DP4=1,2,780,819;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Gga/Cga|G204R|419|N|protein_coding|CODING|GU280_gp10|1|C) +NC_045512.2 28969 . CA C 114.0 PASS DP=1371;AF=0.005106;SB=0;DP4=681,687,3,4;INDEL;HRUN=4;EFF=FRAME_SHIFT(HIGH||atg/|M234|419|N|protein_coding|CODING|GU280_gp10|1|C|INFO_REALIGN_3_PRIME);LOF=(N|GU280_gp10|1|1.00) +NC_045512.2 28981 . T G 109.0 PASS DP=1435;AF=0.006272;SB=450;DP4=570,721,137,0;EFF=SYNONYMOUS_CODING(LOW|SILENT|ggT/ggG|G236|419|N|protein_coding|CODING|GU280_gp10|1|G) +NC_045512.2 29053 . A G 112.0 PASS DP=1408;AF=0.007102;SB=1;DP4=688,703,7,6;EFF=SYNONYMOUS_CODING(LOW|SILENT|caA/caG|Q260|419|N|protein_coding|CODING|GU280_gp10|1|G) diff --git a/example_data/example_mave_data/output/virHEAT_plot_12samples_1score.pdf b/example_data/example_mave_data/output/virHEAT_plot_12samples_1score.pdf new file mode 100644 index 0000000000000000000000000000000000000000..9a30862e96229b42d364fe38d4af36044efc6c71 GIT binary patch literal 43566 zcmb4r2Rzna|945E$S#zr#psBeA0ThdgfNfOnj<(#)fy91fatuCJBlChL*RGj;H@IK-S9AmPrup zz;{hW|F)rlEt3fL@w}t0++|xmTSF!xtU*=J*4EI*l1Ui(xS#K`iQX+!OJk-}JKx$^ z8C*8BWx5V(Wn{q=Lq}UCJ_QRf0k`x2(mVgJz@+^TbNK&n2N1gv>un6dI?Q~&ONMu? z>}(9cAH;spuVi@3R1at62pUhqfB4Uw65$m%b%tL=gh@nDg!h!N(3w+$fbG#s>NNcQ7v+S{mD$F!ApgAZuz4?lbYpnnO%v3=OPq z86sZXwY4$Sv)J#LFj=7(cD%vvso1h^gtYY=E)PiphjWLXdLN?0lV`9cr3*RGe<^~+ zI{0?v38KyEp5t@h%pOh}(n>l1x^u(-UW%xTi&0L?yS{gfhjd++gBZ6rmnAn=UhqkJ ztZsESIjmQ?uPC-vY%p&POzU*VN!Dzyhs90(P~4~*5VqLRFe$ar;oU5^YoyrT4B4t6 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zQ%ik~%naqB?knCqWq65@ycWGlhPnvF4Cb(TNx#+cUN^sRdfpso;e`-E+>^Dnqe-Ws%eZOniHqtfq*`4{=8xHkX* literal 0 HcmV?d00001 diff --git a/virheat/__init__.py b/virheat/__init__.py index 0be322f..d10d6d3 100644 --- a/virheat/__init__.py +++ b/virheat/__init__.py @@ -1,3 +1,3 @@ """plot vcf data as a heatmap mapped to a virus genome""" _program = "virheat" -__version__ = "0.6" +__version__ = "0.7" diff --git a/virheat/command.py b/virheat/command.py index 6d2fde8..b235901 100644 --- a/virheat/command.py +++ b/virheat/command.py @@ -108,6 +108,13 @@ def get_args(sysargs): default=20, help="display mutations covered at least x time (only if per base cov tsv files are provided)" ) + parser.add_argument( + "-s", "--scores", + metavar=('scores_file', 'pos_col', 'score_col', 'score_name'), + nargs=4, + action='append', + help="specify scores to be added to the plot by providing a CSV file containing scores, along with its column for amino-acid positions, its column for scores, and descriptive score names (e.g., expression, binding, antibody escape, etc.). This option can be used multiple times to include multiple sets of scores." + ) parser.add_argument( "-v", "--version", @@ -135,7 +142,10 @@ def main(sysargs=sys.argv[1:]): vcf_files = sorted(vcf_files, key=lambda x: data_prep.get_digit_and_alpha(os.path.basename(x))) # extract vcf info - reference_name, frequency_lists, unique_mutations, file_names = data_prep.extract_vcf_data(vcf_files, threshold=args.threshold) + if args.scores: + reference_name, frequency_lists, unique_mutations, file_names = data_prep.extract_vcf_data(vcf_files, threshold=args.threshold, scores=1) + else: + reference_name, frequency_lists, unique_mutations, file_names = data_prep.extract_vcf_data(vcf_files, threshold=args.threshold) if args.zoom: unique_mutations = data_prep.zoom_to_genomic_regions(unique_mutations, args.zoom) frequency_array = data_prep.create_freq_array(unique_mutations, frequency_lists) @@ -169,16 +179,28 @@ def main(sysargs=sys.argv[1:]): genome_end = data_prep.get_genome_end(gff3_info) genes_with_mutations, n_tracks = data_prep.create_track_dict(unique_mutations, gff3_info, args.gff3_annotations) # define space for the genome vis tracks - min_y_location = genome_y_location + genome_y_location/2 * (n_tracks+1) + if args.scores and n_samples >= 4: + min_y_location = genome_y_location + genome_y_location/2 * (n_tracks+1) + 1.7*len(args.scores) + else: + min_y_location = genome_y_location + genome_y_location/2 * (n_tracks+1) elif args.genome_length is not None: genome_end = args.genome_length - min_y_location = genome_y_location + if args.scores: + if n_samples < 4: + min_y_location = genome_y_location + 2 + len(args.scores) * 0.3 + else: + min_y_location = genome_y_location + math.log2(n_samples) + 1.7 * len(args.scores) + else: + min_y_location = genome_y_location else: sys.exit("\033[31m\033[1mERROR:\033[0m Provide either a gff3 file (-g) or the length (-l) of the genome which you used for mapping") # define size of the plot y_size = n_mutations*0.4 - x_size = y_size*(n_samples+min_y_location)/n_mutations + if args.scores: + x_size = y_size * (n_samples + min_y_location + len(args.scores)) / n_mutations + else: + x_size = y_size*(n_samples+min_y_location)/n_mutations x_size = x_size-x_size*0.15 # compensate of heatmap annotation # ini the fig @@ -201,16 +223,53 @@ def main(sysargs=sys.argv[1:]): cmap_cells = cm.ScalarMappable(norm=colors.Normalize(0, 1), cmap=cmap) plotting.create_heatmap(ax, frequency_array, cmap_cells) mutation_set = plotting.create_genome_vis(ax, genome_y_location, n_mutations, unique_mutations, start, stop) + if args.scores: + scores_files = args.scores + n_scoresets = len(scores_files) + score_count = 0 + plotting.create_axis(ax, n_mutations, min_y_location, n_samples, file_names, start, stop, genome_y_location, unique_mutations, reference_name, n_scoresets) + plotting.create_mutation_legend(mutation_set, min_y_location, n_samples, n_scoresets) + for score_params in args.scores: + score_count += 1 + scores_file, pos_col, score_col, score_name = score_params + unique_scores = data_prep.extract_scores(unique_mutations, scores_file, pos_col, score_col) + score_set = plotting.create_scores_vis(ax, genome_y_location, n_mutations, unique_scores, start, stop, score_name=score_name, score_count=score_count) + cmap_scores = plt.cm.get_cmap('coolwarm') # blue to red colormap + if n_scoresets<3: + plotting.create_scores_cbar(cmap_scores, min_y_location, n_scoresets, score_set, score_name, score_count, ax) + + # plotting colorbars for scorsets if more than 3 scoresets - move colorbars under + if n_scoresets > 2: + ax2 = fig.add_axes(ax.get_position(), frameon=False) + ax2.set_position([ax.get_position().x0, ax.get_position().y0 - 1.1 * ax.get_position().height*0.5, + ax.get_position().width, 0.4]) + ax2.set_xticks([]) + ax2.set_yticks([]) + score_count = 0 + for score_params in args.scores: + score_count += 1 + scores_file, pos_col, score_col, score_name = score_params + unique_scores = data_prep.extract_scores(unique_mutations, scores_file, pos_col, score_col) + score_set = plotting.create_scores_vis(ax, genome_y_location, n_mutations, unique_scores, start, stop, score_name=score_name, score_count=score_count, no_plot=1) + cmap_scores = plt.cm.get_cmap('coolwarm') + plotting.create_scores_cbar(cmap_scores, min_y_location, n_scoresets, score_set, score_name, score_count, ax2) + else: + plotting.create_axis(ax, n_mutations, min_y_location, n_samples, file_names, start, stop, genome_y_location, unique_mutations, reference_name) + plotting.create_mutation_legend(mutation_set, min_y_location, n_samples) + if args.gff3_path is not None: if genes_with_mutations: # distinct colors for the genes cmap_genes = plt.get_cmap('tab20', len(genes_with_mutations)) colors_genes = [cmap_genes(i) for i in range(len(genes_with_mutations))] # plot gene track - plotting.create_gene_vis(ax, genes_with_mutations, n_mutations, y_size, n_tracks, start, stop, min_y_location, genome_y_location, colors_genes) - plotting.create_axis(ax, n_mutations, min_y_location, n_samples, file_names, start, stop, genome_y_location, unique_mutations, reference_name) + if args.scores and n_samples >= 4: + min_y_location_sc = min_y_location - 1.7 * len(args.scores) + plotting.create_gene_vis(ax, genes_with_mutations, n_mutations, y_size, n_tracks, start, stop, min_y_location_sc, genome_y_location, colors_genes) + else: + plotting.create_gene_vis(ax, genes_with_mutations, n_mutations, y_size, n_tracks, start, stop, min_y_location, genome_y_location, colors_genes) + plotting.create_colorbar(args.threshold, cmap_cells, min_y_location, n_samples, ax) - plotting.create_mutation_legend(mutation_set, min_y_location, n_samples) # create output folder if not os.path.exists(args.input[1]): diff --git a/virheat/scripts/data_prep.py b/virheat/scripts/data_prep.py index 45ca30e..d174e42 100644 --- a/virheat/scripts/data_prep.py +++ b/virheat/scripts/data_prep.py @@ -100,7 +100,7 @@ def read_vcf(vcf_file): return vcf_dict -def extract_vcf_data(vcf_files, threshold=0): +def extract_vcf_data(vcf_files, threshold=0, scores=None): """ extract relevant vcf data """ @@ -116,9 +116,19 @@ def extract_vcf_data(vcf_files, threshold=0): for idx in range(0, len(vcf_dict["#CHROM"])): if not vcf_dict["AF"][idx] >= threshold: continue - frequency_list.append( - (f"{vcf_dict['POS'][idx]}_{vcf_dict['REF'][idx]}_{vcf_dict['ALT'][idx]}_{vcf_dict['MUT_TYPE_'][idx]}", vcf_dict['AF'][idx]) - ) + if scores: + if vcf_dict['EFF'][idx] is not None: + aa_change = vcf_dict['EFF'][idx].split('|')[3] # extract amino acid changes if provided + else: + aa_change = '-' + frequency_list.append( + (f"{vcf_dict['POS'][idx]}_{vcf_dict['REF'][idx]}_{vcf_dict['ALT'][idx]}_{vcf_dict['MUT_TYPE_'][idx]}_{aa_change}", vcf_dict['AF'][idx]) + ) + else: + frequency_list.append( + (f"{vcf_dict['POS'][idx]}_{vcf_dict['REF'][idx]}_{vcf_dict['ALT'][idx]}_{vcf_dict['MUT_TYPE_'][idx]}", vcf_dict['AF'][idx]) + ) + frequency_lists.append(frequency_list) # sort by mutation index unique_mutations = sorted( @@ -128,6 +138,29 @@ def extract_vcf_data(vcf_files, threshold=0): return vcf_dict["#CHROM"][0], frequency_lists, unique_mutations, file_names +def extract_scores(unique_mutations, scores_file, aa_pos_col, score_col): + """ + Extract scores from scores_file which corresponding value from aa_pos_col is equal to unique_aa_mutations + """ + scores_df = pd.read_csv(scores_file) + + # create a dictionary to store the scores for each mutation + mutation_scores = {} + for idx, row in scores_df.iterrows(): + mutation_scores[row[aa_pos_col]] = row[score_col] + + unique_scores = [] + for mutation in unique_mutations: + aa_mut = mutation.split('_')[4] + if aa_mut in mutation_scores: + score = mutation_scores[aa_mut] + unique_scores.append(f"{mutation}_{score}") + else: + unique_scores.append(f"{mutation}_nan") + + return unique_scores + + def create_freq_array(unique_mutations, frequency_lists): """ create an np array of the mutation frequencies @@ -334,4 +367,4 @@ def create_track_dict(unique_mutations, gff3_info, annotation_type): # and indicate the track in the dict gene_dict[gene].append(track) - return gene_dict, len(track_stops) + return gene_dict, len(track_stops) \ No newline at end of file diff --git a/virheat/scripts/plotting.py b/virheat/scripts/plotting.py index 415a018..d13aff9 100644 --- a/virheat/scripts/plotting.py +++ b/virheat/scripts/plotting.py @@ -4,10 +4,14 @@ # BUILT-INS import math +import numpy as np +import textwrap # LIBS import matplotlib.pyplot as plt import matplotlib.patches as patches +import matplotlib.colors as mcolors +import matplotlib.cm as cm def create_heatmap(ax, frequency_array, cmap): @@ -67,6 +71,70 @@ def create_genome_vis(ax, genome_y_location, n_mutations, unique_mutations, star return mutation_set +def create_scores_vis(ax, genome_y_location, n_mutations, unique_mutations, start, stop, score_name=None, score_count=None, no_plot=0): + """ + create the scores rectangles, mappings to the reference + """ + y_min = -genome_y_location + y_max = -genome_y_location+genome_y_location/2 + if score_name: + score_set = [] + for mutation in unique_mutations: + mutation_attributes = mutation.split("_") + score_set.append(float(mutation_attributes[5])) + score_set = [value for value in score_set if not np.isnan(value)] + if score_set: + norm = mcolors.Normalize(vmin=min(score_set), vmax=max(score_set)) # Normalization for the score range + else: + print("\033[31m\033[1mERROR:\033[0m Seems like there are no scores in the score set '{}' corresponding to the plotted mutation positions.".format(score_name)) + cmap = plt.cm.get_cmap('coolwarm') # blue to red colormap + ax.text(-0.02 * n_mutations, y_min - (score_count + 1.5) * (genome_y_location / 2), score_name, ha='right', va='center') + + # create a rectangle for the scores + rect = patches.FancyBboxPatch( + (0, y_min - (score_count + 2) * (genome_y_location / 2)), n_mutations*1.5, y_max - y_min, + boxstyle="round,pad=-0.0040,rounding_size=0.03", + ec="lightgray", fc=(0, 0, 0, 0.05) + ) + ax.add_patch(rect) + + # create score lines on the score rectangle and the mapping to the respective mutation lines + x_start = 0 + length = stop - start + for mutation in unique_mutations: + mutation_attributes = mutation.split("_") + mutation_x_location = n_mutations/length*(int(mutation_attributes[0])-start) + x_start += 1 + # create lines for score_set + if score_name and no_plot !=1: + if score_set: + score_value = float(mutation_attributes[5]) + if score_value in score_set: + color = cmap(norm(score_value)) # map score to colormap + plt.vlines(x=mutation_x_location, ymin=y_min - (score_count + 2) * (genome_y_location / 2), ymax=y_max - (score_count + 2) * (genome_y_location / 2), color=color, linestyle='-') + + return score_set + + +def create_scores_cbar(cmap, min_y_location, n_scoresets, score_set, score_name, score_count, ax): + """ + create a colorbar for the scoreset + """ + if score_set: + if n_scoresets<3: + cbar = plt.colorbar(cm.ScalarMappable(cmap=cmap, norm=mcolors.Normalize(vmin=min(score_set), vmax=max(score_set))), + pad=0, shrink=1.5 / (min_y_location + 1), anchor=(-0.8, 0), + aspect=15, orientation='vertical', ax=ax, label=score_name) + else: + cbar = plt.colorbar(cm.ScalarMappable(cmap=cmap, norm=mcolors.Normalize(vmin=min(score_set), vmax=max(score_set))), label=score_name, ax=ax) + ax_pos = ax.get_position() + cbar.ax.set_position([ax_pos.x0 + score_count * 0.05, ax_pos.y0, ax_pos.width * 0.7, ax_pos.height*0.9]) + ticks = [min(score_set), min(score_set)+abs((max(score_set)-min(score_set))/2), max(score_set), 0] + cbar.set_ticks(ticks) + cbar.ax.tick_params(direction='in', labelsize='x-small') + cbar.set_label('\n'.join(textwrap.wrap(score_name, 20)), size='x-small') + + def create_colorbar(threshold, cmap, min_y_location, n_samples, ax): """ creates a custom colorbar and annotates the threshold @@ -96,7 +164,7 @@ def create_colorbar(threshold, cmap, min_y_location, n_samples, ax): cbar.set_ticklabels(labels) -def create_mutation_legend(mutation_set, min_y_location, n_samples): +def create_mutation_legend(mutation_set, min_y_location, n_samples, n_scoresets=0): """ create a legend for the mutation type """ @@ -109,17 +177,20 @@ def create_mutation_legend(mutation_set, min_y_location, n_samples): if "SNV" in mutation_set: legend_patches.append(patches.Patch(color="dimgrey", label="SNV")) - plt.legend(bbox_to_anchor=(1.01, 0.95-(n_samples/(min_y_location+n_samples))), handles=legend_patches) + if n_scoresets != 0: + plt.legend(handles=legend_patches, bbox_to_anchor=(1.02, 0.95 - (n_samples / (min_y_location + n_samples))), loc='upper left', ncol=len(legend_patches)) + else: + plt.legend(bbox_to_anchor=(1.01, 0.95-(n_samples/(min_y_location+n_samples))), handles=legend_patches) -def create_axis(ax, n_mutations, min_y_location, n_samples, file_names, start, stop, genome_y_location, unique_mutations, reference_name): +def create_axis(ax, n_mutations, min_y_location, n_samples, file_names, start, stop, genome_y_location, unique_mutations, reference_name, n_scoresets=0): """ create the axis of the plot """ # define plot limits ax.set_xlim(0, n_mutations) - ax.set_ylim(-min_y_location, n_samples) + ax.set_ylim(-min_y_location - n_scoresets, n_samples) # define new ticks depending on the genome size axis_length = stop - start if n_mutations >= 20: From 36fa0286751c86b14b5a37e5aaeb13764c78f98a Mon Sep 17 00:00:00 2001 From: PlushZ Date: Tue, 7 May 2024 14:08:51 +0200 Subject: [PATCH 02/10] fix dynamic link in readme --- README.md | 3 ++- 1 file changed, 2 insertions(+), 1 deletion(-) diff --git a/README.md b/README.md index 8d6091c..cad6a5d 100644 --- a/README.md +++ b/README.md @@ -90,7 +90,8 @@ Additionally, you can also analyse if mutations are sufficiently covered and dis Moreover, there is an option to include visualizations of additional scores (e.g., MAVE scores for binding affinity, expression level, antibody escape, etc.) mapped to mutations on the heatmap. To utilize this feature, use the -s or --scores argument, and provide the following arguments: 1) path to the CSV file containing scores; 2) the name of the column in this file containing mutation positions in classic notation (e.g., T430Y); 3) the name of the column in this file containing the scores themselves; 4) a descriptive score name that will be used as labels in the plot. Multiple score sets can be included simultaneously by repeating the -s or --scores option with different arguments. For example input and possible output data, -please refer to the files located in the [example_data/example_mave_data](https://github.com/{repo}/tree/main/example_data/example_mave_data) folder. +please refer to the files located in the [example_data/example_mave_data](./example_data/example_mave_data) folder. + --- **Important disclaimer:** From 5fbaaa2ce2a157ceebe8485575de8b88903b2501 Mon Sep 17 00:00:00 2001 From: jonas-fuchs Date: Wed, 15 May 2024 15:56:23 +0200 Subject: [PATCH 03/10] fixed location issues --- .../example_mave_data/input/MaveExpRBD.csv | 2 +- virheat/command.py | 84 +++++++++---------- virheat/scripts/plotting.py | 29 +++---- 3 files changed, 56 insertions(+), 59 deletions(-) diff --git a/example_data/example_mave_data/input/MaveExpRBD.csv b/example_data/example_mave_data/input/MaveExpRBD.csv index 75ba9aa..b87b02c 100644 --- a/example_data/example_mave_data/input/MaveExpRBD.csv +++ b/example_data/example_mave_data/input/MaveExpRBD.csv @@ -1,4 +1,4 @@ -accession,hgvs_nt,hgvs_splice,hgvs_pro,score,average,library,AA +vi-s-accession,hgvs_nt,hgvs_splice,hgvs_pro,score,average,library,AA urn:mavedb:00000044-b-2#4199,NA,NA,p.Ala105*,-4.58,-4.57,1,A435 urn:mavedb:00000044-b-2#4200,NA,NA,p.Ala105*,-4.55,-4.57,2,A435 urn:mavedb:00000044-b-2#4187,NA,NA,p.Ala105Arg,-2.86,-2.82,1,A435R diff --git a/virheat/command.py b/virheat/command.py index b235901..96abda1 100644 --- a/virheat/command.py +++ b/virheat/command.py @@ -142,8 +142,10 @@ def main(sysargs=sys.argv[1:]): vcf_files = sorted(vcf_files, key=lambda x: data_prep.get_digit_and_alpha(os.path.basename(x))) # extract vcf info + n_scores = 0 if args.scores: reference_name, frequency_lists, unique_mutations, file_names = data_prep.extract_vcf_data(vcf_files, threshold=args.threshold, scores=1) + n_scores = len(args.scores) else: reference_name, frequency_lists, unique_mutations, file_names = data_prep.extract_vcf_data(vcf_files, threshold=args.threshold) if args.zoom: @@ -156,7 +158,7 @@ def main(sysargs=sys.argv[1:]): if args.delete_n is not None: frequency_array = data_prep.delete_n_mutations(frequency_array, unique_mutations, args.delete_n) - # annotate low coverage if per base coveage from qualimap was provided + # annotate low coverage if per base coverage from qualimap was provided data_prep.annotate_non_covered_regions(args.input[0], args.min_cov, frequency_array, file_names, unique_mutations) # define relative locations of all items in the plot @@ -168,7 +170,7 @@ def main(sysargs=sys.argv[1:]): else: genome_y_location = math.log2(n_samples) - # gff3 data extraction + # gff3 data extraction and define y coordinates if args.gff3_path is not None and args.genome_length is not None: sys.exit("\033[31m\033[1mERROR:\033[0m Do not provide the -g and -l argument simultaneously!") elif args.gff3_path is not None: @@ -178,29 +180,24 @@ def main(sysargs=sys.argv[1:]): print("\033[31m\033[1mWARNING:\033[0m gff3 reference does not match the vcf reference!") genome_end = data_prep.get_genome_end(gff3_info) genes_with_mutations, n_tracks = data_prep.create_track_dict(unique_mutations, gff3_info, args.gff3_annotations) - # define space for the genome vis tracks - if args.scores and n_samples >= 4: - min_y_location = genome_y_location + genome_y_location/2 * (n_tracks+1) + 1.7*len(args.scores) - else: - min_y_location = genome_y_location + genome_y_location/2 * (n_tracks+1) elif args.genome_length is not None: genome_end = args.genome_length - if args.scores: - if n_samples < 4: - min_y_location = genome_y_location + 2 + len(args.scores) * 0.3 - else: - min_y_location = genome_y_location + math.log2(n_samples) + 1.7 * len(args.scores) - else: - min_y_location = genome_y_location + n_tracks = 0 else: sys.exit("\033[31m\033[1mERROR:\033[0m Provide either a gff3 file (-g) or the length (-l) of the genome which you used for mapping") + # define min y coordinate + if n_tracks != 0 or n_scores != 0: + min_y_location = genome_y_location + genome_y_location / 2 * (n_tracks + n_scores + 1) + else: + min_y_location = genome_y_location + # define size of the plot y_size = n_mutations*0.4 if args.scores: x_size = y_size * (n_samples + min_y_location + len(args.scores)) / n_mutations else: - x_size = y_size*(n_samples+min_y_location)/n_mutations + x_size = y_size*(n_samples + min_y_location)/n_mutations x_size = x_size-x_size*0.15 # compensate of heatmap annotation # ini the fig @@ -217,45 +214,46 @@ def main(sysargs=sys.argv[1:]): else: start, stop = 0, genome_end - # plot all elements + # plot all common elements cmap = cm.gist_heat_r cmap.set_bad('silver', 1.) cmap_cells = cm.ScalarMappable(norm=colors.Normalize(0, 1), cmap=cmap) plotting.create_heatmap(ax, frequency_array, cmap_cells) mutation_set = plotting.create_genome_vis(ax, genome_y_location, n_mutations, unique_mutations, start, stop) + plotting.create_axis(ax, n_mutations, min_y_location, n_samples, file_names, start, stop, genome_y_location, + unique_mutations, reference_name, n_scores) + plotting.create_mutation_legend(mutation_set, min_y_location, n_samples, n_scores) + plotting.create_colorbar(args.threshold, cmap_cells, min_y_location, n_samples, ax, n_scores) + # plot scores as track below the genome track if args.scores: - scores_files = args.scores - n_scoresets = len(scores_files) - score_count = 0 - plotting.create_axis(ax, n_mutations, min_y_location, n_samples, file_names, start, stop, genome_y_location, unique_mutations, reference_name, n_scoresets) - plotting.create_mutation_legend(mutation_set, min_y_location, n_samples, n_scoresets) + score_count = 1 for score_params in args.scores: score_count += 1 scores_file, pos_col, score_col, score_name = score_params unique_scores = data_prep.extract_scores(unique_mutations, scores_file, pos_col, score_col) - score_set = plotting.create_scores_vis(ax, genome_y_location, n_mutations, unique_scores, start, stop, score_name=score_name, score_count=score_count) - cmap_scores = plt.cm.get_cmap('coolwarm') # blue to red colormap - if n_scoresets<3: - plotting.create_scores_cbar(cmap_scores, min_y_location, n_scoresets, score_set, score_name, score_count, ax) + plotting.create_scores_vis(ax, genome_y_location, n_mutations, n_tracks, unique_scores, start, stop, score_name=score_name, score_count=score_count) + + + + #cmap_scores = plt.cm.get_cmap('coolwarm') # blue to red colormap + #if n_scoresets < 3: + # plotting.create_scores_cbar(cmap_scores, min_y_location, n_scoresets, score_set, score_name, score_count, ax) # plotting colorbars for scorsets if more than 3 scoresets - move colorbars under - if n_scoresets > 2: - ax2 = fig.add_axes(ax.get_position(), frameon=False) - ax2.set_position([ax.get_position().x0, ax.get_position().y0 - 1.1 * ax.get_position().height*0.5, - ax.get_position().width, 0.4]) - ax2.set_xticks([]) - ax2.set_yticks([]) - score_count = 0 - for score_params in args.scores: - score_count += 1 - scores_file, pos_col, score_col, score_name = score_params - unique_scores = data_prep.extract_scores(unique_mutations, scores_file, pos_col, score_col) - score_set = plotting.create_scores_vis(ax, genome_y_location, n_mutations, unique_scores, start, stop, score_name=score_name, score_count=score_count, no_plot=1) - cmap_scores = plt.cm.get_cmap('coolwarm') - plotting.create_scores_cbar(cmap_scores, min_y_location, n_scoresets, score_set, score_name, score_count, ax2) - else: - plotting.create_axis(ax, n_mutations, min_y_location, n_samples, file_names, start, stop, genome_y_location, unique_mutations, reference_name) - plotting.create_mutation_legend(mutation_set, min_y_location, n_samples) + # if n_scoresets > 2: + # ax2 = fig.add_axes(ax.get_position(), frameon=False) + # ax2.set_position([ax.get_position().x0, ax.get_position().y0 - 1.1 * ax.get_position().height*0.5, + # ax.get_position().width, 0.4]) + # ax2.set_xticks([]) + # ax2.set_yticks([]) + # score_count = 0 + # for score_params in args.scores: + # score_count += 1 + # scores_file, pos_col, score_col, score_name = score_params + # unique_scores = data_prep.extract_scores(unique_mutations, scores_file, pos_col, score_col) + # score_set = plotting.create_scores_vis(ax, genome_y_location, n_mutations, unique_scores, start, stop, score_name=score_name, score_count=score_count, no_plot=1) + # cmap_scores = plt.cm.get_cmap('coolwarm') + # #plotting.create_scores_cbar(cmap_scores, min_y_location, n_scoresets, score_set, score_name, score_count, ax2) if args.gff3_path is not None: if genes_with_mutations: @@ -269,8 +267,6 @@ def main(sysargs=sys.argv[1:]): else: plotting.create_gene_vis(ax, genes_with_mutations, n_mutations, y_size, n_tracks, start, stop, min_y_location, genome_y_location, colors_genes) - plotting.create_colorbar(args.threshold, cmap_cells, min_y_location, n_samples, ax) - # create output folder if not os.path.exists(args.input[1]): os.makedirs(args.input[1]) diff --git a/virheat/scripts/plotting.py b/virheat/scripts/plotting.py index d13aff9..e1f5741 100644 --- a/virheat/scripts/plotting.py +++ b/virheat/scripts/plotting.py @@ -71,14 +71,16 @@ def create_genome_vis(ax, genome_y_location, n_mutations, unique_mutations, star return mutation_set -def create_scores_vis(ax, genome_y_location, n_mutations, unique_mutations, start, stop, score_name=None, score_count=None, no_plot=0): +def create_scores_vis(ax, genome_y_location, n_mutations, n_tracks, unique_mutations, start, stop, score_name=None, score_count=None): """ create the scores rectangles, mappings to the reference """ - y_min = -genome_y_location - y_max = -genome_y_location+genome_y_location/2 + score_set = [] + + y_min = -genome_y_location - (n_tracks+1)*(genome_y_location/2) - score_count*(genome_y_location/2) + y_max = y_min + genome_y_location / 2 + if score_name: - score_set = [] for mutation in unique_mutations: mutation_attributes = mutation.split("_") score_set.append(float(mutation_attributes[5])) @@ -88,11 +90,11 @@ def create_scores_vis(ax, genome_y_location, n_mutations, unique_mutations, star else: print("\033[31m\033[1mERROR:\033[0m Seems like there are no scores in the score set '{}' corresponding to the plotted mutation positions.".format(score_name)) cmap = plt.cm.get_cmap('coolwarm') # blue to red colormap - ax.text(-0.02 * n_mutations, y_min - (score_count + 1.5) * (genome_y_location / 2), score_name, ha='right', va='center') + ax.text(-0.02 * n_mutations, y_min+genome_y_location/4, score_name, ha='right', va='center') # create a rectangle for the scores rect = patches.FancyBboxPatch( - (0, y_min - (score_count + 2) * (genome_y_location / 2)), n_mutations*1.5, y_max - y_min, + (0, y_min), n_mutations, y_max - y_min, boxstyle="round,pad=-0.0040,rounding_size=0.03", ec="lightgray", fc=(0, 0, 0, 0.05) ) @@ -106,12 +108,11 @@ def create_scores_vis(ax, genome_y_location, n_mutations, unique_mutations, star mutation_x_location = n_mutations/length*(int(mutation_attributes[0])-start) x_start += 1 # create lines for score_set - if score_name and no_plot !=1: - if score_set: - score_value = float(mutation_attributes[5]) - if score_value in score_set: - color = cmap(norm(score_value)) # map score to colormap - plt.vlines(x=mutation_x_location, ymin=y_min - (score_count + 2) * (genome_y_location / 2), ymax=y_max - (score_count + 2) * (genome_y_location / 2), color=color, linestyle='-') + if score_name and score_set: + score_value = float(mutation_attributes[5]) + if score_value in score_set: + color = cmap(norm(score_value)) # map score to colormap + plt.vlines(x=mutation_x_location, ymin=y_min, ymax=y_max, color=color, linestyle='-') return score_set @@ -135,7 +136,7 @@ def create_scores_cbar(cmap, min_y_location, n_scoresets, score_set, score_name, cbar.set_label('\n'.join(textwrap.wrap(score_name, 20)), size='x-small') -def create_colorbar(threshold, cmap, min_y_location, n_samples, ax): +def create_colorbar(threshold, cmap, min_y_location, n_samples, ax, n_scores=0): """ creates a custom colorbar and annotates the threshold """ @@ -159,7 +160,7 @@ def create_colorbar(threshold, cmap, min_y_location, n_samples, ax): labels.remove(rounded_threshold) ticks.append(threshold) labels.append(f"threshold\n={threshold}") - cbar = plt.colorbar(cmap, label="variant frequency", pad=0, shrink=n_samples/(min_y_location+n_samples), anchor=(0.1,1), aspect=15, ax=ax) + cbar = plt.colorbar(cmap, label="variant frequency", pad=0, shrink=n_samples/(min_y_location+n_samples+n_scores), anchor=(0.1,1), aspect=15, ax=ax) cbar.set_ticks(ticks) cbar.set_ticklabels(labels) From d61cb7b1a80f6eb249c3a3ff29c843b9422fa377 Mon Sep 17 00:00:00 2001 From: jonas-fuchs Date: Wed, 15 May 2024 16:19:08 +0200 Subject: [PATCH 04/10] fixed text alignment for score identifier --- virheat/scripts/plotting.py | 8 +++++--- 1 file changed, 5 insertions(+), 3 deletions(-) diff --git a/virheat/scripts/plotting.py b/virheat/scripts/plotting.py index e1f5741..0d832c1 100644 --- a/virheat/scripts/plotting.py +++ b/virheat/scripts/plotting.py @@ -76,8 +76,10 @@ def create_scores_vis(ax, genome_y_location, n_mutations, n_tracks, unique_mutat create the scores rectangles, mappings to the reference """ score_set = [] - - y_min = -genome_y_location - (n_tracks+1)*(genome_y_location/2) - score_count*(genome_y_location/2) + if n_tracks == 0: + y_min = -genome_y_location - 1 - score_count * (genome_y_location / 2) + else: + y_min = -genome_y_location - (n_tracks + 1) * (genome_y_location / 2) - score_count * (genome_y_location / 2) y_max = y_min + genome_y_location / 2 if score_name: @@ -90,7 +92,7 @@ def create_scores_vis(ax, genome_y_location, n_mutations, n_tracks, unique_mutat else: print("\033[31m\033[1mERROR:\033[0m Seems like there are no scores in the score set '{}' corresponding to the plotted mutation positions.".format(score_name)) cmap = plt.cm.get_cmap('coolwarm') # blue to red colormap - ax.text(-0.02 * n_mutations, y_min+genome_y_location/4, score_name, ha='right', va='center') + ax.text(-0.5, y_min+genome_y_location/4, score_name, ha='right', va='center') # create a rectangle for the scores rect = patches.FancyBboxPatch( From 71f1fb4a685abcbe925911b0ee1467d1db07b569 Mon Sep 17 00:00:00 2001 From: jonas-fuchs Date: Fri, 17 May 2024 13:54:10 +0200 Subject: [PATCH 05/10] changed plotting type for scores --- virheat/command.py | 41 +++----------- virheat/scripts/data_prep.py | 8 ++- virheat/scripts/plotting.py | 103 +++++++++++------------------------ 3 files changed, 46 insertions(+), 106 deletions(-) diff --git a/virheat/command.py b/virheat/command.py index 96abda1..dd1fcf4 100644 --- a/virheat/command.py +++ b/virheat/command.py @@ -144,7 +144,7 @@ def main(sysargs=sys.argv[1:]): # extract vcf info n_scores = 0 if args.scores: - reference_name, frequency_lists, unique_mutations, file_names = data_prep.extract_vcf_data(vcf_files, threshold=args.threshold, scores=1) + reference_name, frequency_lists, unique_mutations, file_names = data_prep.extract_vcf_data(vcf_files, threshold=args.threshold, scores=True) n_scores = len(args.scores) else: reference_name, frequency_lists, unique_mutations, file_names = data_prep.extract_vcf_data(vcf_files, threshold=args.threshold) @@ -188,14 +188,14 @@ def main(sysargs=sys.argv[1:]): # define min y coordinate if n_tracks != 0 or n_scores != 0: - min_y_location = genome_y_location + genome_y_location / 2 * (n_tracks + n_scores + 1) + min_y_location = genome_y_location + genome_y_location / 2 * (n_tracks + n_scores + 2) else: min_y_location = genome_y_location # define size of the plot y_size = n_mutations*0.4 if args.scores: - x_size = y_size * (n_samples + min_y_location + len(args.scores)) / n_mutations + x_size = y_size * (n_samples + min_y_location + n_scores) / n_mutations else: x_size = y_size*(n_samples + min_y_location)/n_mutations x_size = x_size-x_size*0.15 # compensate of heatmap annotation @@ -223,37 +223,16 @@ def main(sysargs=sys.argv[1:]): plotting.create_axis(ax, n_mutations, min_y_location, n_samples, file_names, start, stop, genome_y_location, unique_mutations, reference_name, n_scores) plotting.create_mutation_legend(mutation_set, min_y_location, n_samples, n_scores) - plotting.create_colorbar(args.threshold, cmap_cells, min_y_location, n_samples, ax, n_scores) + plotting.create_colorbar(args.threshold, cmap_cells, min_y_location, n_samples, ax) # plot scores as track below the genome track if args.scores: score_count = 1 for score_params in args.scores: - score_count += 1 scores_file, pos_col, score_col, score_name = score_params unique_scores = data_prep.extract_scores(unique_mutations, scores_file, pos_col, score_col) - plotting.create_scores_vis(ax, genome_y_location, n_mutations, n_tracks, unique_scores, start, stop, score_name=score_name, score_count=score_count) - - - - #cmap_scores = plt.cm.get_cmap('coolwarm') # blue to red colormap - #if n_scoresets < 3: - # plotting.create_scores_cbar(cmap_scores, min_y_location, n_scoresets, score_set, score_name, score_count, ax) - - # plotting colorbars for scorsets if more than 3 scoresets - move colorbars under - # if n_scoresets > 2: - # ax2 = fig.add_axes(ax.get_position(), frameon=False) - # ax2.set_position([ax.get_position().x0, ax.get_position().y0 - 1.1 * ax.get_position().height*0.5, - # ax.get_position().width, 0.4]) - # ax2.set_xticks([]) - # ax2.set_yticks([]) - # score_count = 0 - # for score_params in args.scores: - # score_count += 1 - # scores_file, pos_col, score_col, score_name = score_params - # unique_scores = data_prep.extract_scores(unique_mutations, scores_file, pos_col, score_col) - # score_set = plotting.create_scores_vis(ax, genome_y_location, n_mutations, unique_scores, start, stop, score_name=score_name, score_count=score_count, no_plot=1) - # cmap_scores = plt.cm.get_cmap('coolwarm') - # #plotting.create_scores_cbar(cmap_scores, min_y_location, n_scoresets, score_set, score_name, score_count, ax2) + track_created = plotting.create_scores_vis(ax, genome_y_location, n_mutations, n_tracks, unique_scores, start, stop, score_count, score_name) + if track_created: + score_count += 1 if args.gff3_path is not None: if genes_with_mutations: @@ -261,11 +240,7 @@ def main(sysargs=sys.argv[1:]): cmap_genes = plt.get_cmap('tab20', len(genes_with_mutations)) colors_genes = [cmap_genes(i) for i in range(len(genes_with_mutations))] # plot gene track - if args.scores and n_samples >= 4: - min_y_location_sc = min_y_location - 1.7 * len(args.scores) - plotting.create_gene_vis(ax, genes_with_mutations, n_mutations, y_size, n_tracks, start, stop, min_y_location_sc, genome_y_location, colors_genes) - else: - plotting.create_gene_vis(ax, genes_with_mutations, n_mutations, y_size, n_tracks, start, stop, min_y_location, genome_y_location, colors_genes) + plotting.create_gene_vis(ax, genes_with_mutations, n_mutations, y_size, n_tracks, start, stop, min_y_location, genome_y_location, colors_genes, n_scores) # create output folder if not os.path.exists(args.input[1]): diff --git a/virheat/scripts/data_prep.py b/virheat/scripts/data_prep.py index d174e42..af1c957 100644 --- a/virheat/scripts/data_prep.py +++ b/virheat/scripts/data_prep.py @@ -100,7 +100,7 @@ def read_vcf(vcf_file): return vcf_dict -def extract_vcf_data(vcf_files, threshold=0, scores=None): +def extract_vcf_data(vcf_files, threshold=0, scores=False): """ extract relevant vcf data """ @@ -118,7 +118,7 @@ def extract_vcf_data(vcf_files, threshold=0, scores=None): continue if scores: if vcf_dict['EFF'][idx] is not None: - aa_change = vcf_dict['EFF'][idx].split('|')[3] # extract amino acid changes if provided + aa_change = vcf_dict['EFF'][idx].split('|')[3] # extract amino acid changes if provided else: aa_change = '-' frequency_list.append( @@ -228,6 +228,7 @@ def delete_common_mutations(frequency_array, unique_mutations): return np.delete(frequency_array, mut_to_del, axis=1) + def delete_n_mutations(frequency_array, unique_mutations, min_mut): """ delete mutations that are not present in more than n samples @@ -261,6 +262,7 @@ def zoom_to_genomic_regions(unique_mutations, start_stop): return zoomed_unique + def parse_gff3(file): """ parse gff3 to dictionary @@ -367,4 +369,4 @@ def create_track_dict(unique_mutations, gff3_info, annotation_type): # and indicate the track in the dict gene_dict[gene].append(track) - return gene_dict, len(track_stops) \ No newline at end of file + return gene_dict, len(track_stops) diff --git a/virheat/scripts/plotting.py b/virheat/scripts/plotting.py index 0d832c1..9cf4e65 100644 --- a/virheat/scripts/plotting.py +++ b/virheat/scripts/plotting.py @@ -5,14 +5,11 @@ # BUILT-INS import math import numpy as np -import textwrap # LIBS import matplotlib.pyplot as plt import matplotlib.patches as patches import matplotlib.colors as mcolors -import matplotlib.cm as cm - def create_heatmap(ax, frequency_array, cmap): """ @@ -71,74 +68,44 @@ def create_genome_vis(ax, genome_y_location, n_mutations, unique_mutations, star return mutation_set -def create_scores_vis(ax, genome_y_location, n_mutations, n_tracks, unique_mutations, start, stop, score_name=None, score_count=None): +def create_scores_vis(ax, genome_y_location, n_mutations, n_tracks, unique_mutations, start, stop, score_count, score_name): """ create the scores rectangles, mappings to the reference """ score_set = [] - if n_tracks == 0: - y_min = -genome_y_location - 1 - score_count * (genome_y_location / 2) - else: - y_min = -genome_y_location - (n_tracks + 1) * (genome_y_location / 2) - score_count * (genome_y_location / 2) - y_max = y_min + genome_y_location / 2 - - if score_name: - for mutation in unique_mutations: - mutation_attributes = mutation.split("_") - score_set.append(float(mutation_attributes[5])) - score_set = [value for value in score_set if not np.isnan(value)] - if score_set: - norm = mcolors.Normalize(vmin=min(score_set), vmax=max(score_set)) # Normalization for the score range - else: - print("\033[31m\033[1mERROR:\033[0m Seems like there are no scores in the score set '{}' corresponding to the plotted mutation positions.".format(score_name)) - cmap = plt.cm.get_cmap('coolwarm') # blue to red colormap - ax.text(-0.5, y_min+genome_y_location/4, score_name, ha='right', va='center') - - # create a rectangle for the scores - rect = patches.FancyBboxPatch( - (0, y_min), n_mutations, y_max - y_min, - boxstyle="round,pad=-0.0040,rounding_size=0.03", - ec="lightgray", fc=(0, 0, 0, 0.05) - ) - ax.add_patch(rect) - - # create score lines on the score rectangle and the mapping to the respective mutation lines - x_start = 0 + y_zero = -genome_y_location - (n_tracks + score_count + 1) * (genome_y_location / 2) length = stop - start + + # create list of tuples [(nt pos, score)] for mutation in unique_mutations: mutation_attributes = mutation.split("_") - mutation_x_location = n_mutations/length*(int(mutation_attributes[0])-start) - x_start += 1 - # create lines for score_set - if score_name and score_set: - score_value = float(mutation_attributes[5]) - if score_value in score_set: - color = cmap(norm(score_value)) # map score to colormap - plt.vlines(x=mutation_x_location, ymin=y_min, ymax=y_max, color=color, linestyle='-') - - return score_set - + if not np.isnan(float(mutation_attributes[5])): + score_set.append((int(mutation_attributes[0]), float(mutation_attributes[5]))) -def create_scores_cbar(cmap, min_y_location, n_scoresets, score_set, score_name, score_count, ax): - """ - create a colorbar for the scoreset - """ if score_set: - if n_scoresets<3: - cbar = plt.colorbar(cm.ScalarMappable(cmap=cmap, norm=mcolors.Normalize(vmin=min(score_set), vmax=max(score_set))), - pad=0, shrink=1.5 / (min_y_location + 1), anchor=(-0.8, 0), - aspect=15, orientation='vertical', ax=ax, label=score_name) - else: - cbar = plt.colorbar(cm.ScalarMappable(cmap=cmap, norm=mcolors.Normalize(vmin=min(score_set), vmax=max(score_set))), label=score_name, ax=ax) - ax_pos = ax.get_position() - cbar.ax.set_position([ax_pos.x0 + score_count * 0.05, ax_pos.y0, ax_pos.width * 0.7, ax_pos.height*0.9]) - ticks = [min(score_set), min(score_set)+abs((max(score_set)-min(score_set))/2), max(score_set), 0] - cbar.set_ticks(ticks) - cbar.ax.tick_params(direction='in', labelsize='x-small') - cbar.set_label('\n'.join(textwrap.wrap(score_name, 20)), size='x-small') + # create zero line and score name on the left + plt.axhline(y=y_zero, color='black', linestyle='-', linewidth=0.5) + ax.text(-0.5, y_zero, score_name, ha='right', va='center') + # define normalization multiplier + multiplier = max([abs(score[1]) for score in score_set]) / abs((y_zero + genome_y_location / 4) - y_zero) + + # create score lines on the score rectangle and the mapping to the respective mutation lines + for score in score_set: + # define x value + mutation_x_location = n_mutations / length * (score[0] - start) + # define y value + # create lines for score_set + if score[1] < 0: + plt.vlines(x=mutation_x_location, ymin=y_zero + score[1]/multiplier, ymax=y_zero, color="red", linestyle='-') + else: + plt.vlines(x=mutation_x_location, ymin=y_zero, ymax=y_zero + score[1] / multiplier, color="blue", linestyle='-') + return True + else: + print("\033[31m\033[1mERROR:\033[0m Seems like there are no scores in the score set '{}' corresponding to the plotted mutation positions.".format(score_name)) + return False -def create_colorbar(threshold, cmap, min_y_location, n_samples, ax, n_scores=0): +def create_colorbar(threshold, cmap, min_y_location, n_samples, ax): """ creates a custom colorbar and annotates the threshold """ @@ -162,12 +129,12 @@ def create_colorbar(threshold, cmap, min_y_location, n_samples, ax, n_scores=0): labels.remove(rounded_threshold) ticks.append(threshold) labels.append(f"threshold\n={threshold}") - cbar = plt.colorbar(cmap, label="variant frequency", pad=0, shrink=n_samples/(min_y_location+n_samples+n_scores), anchor=(0.1,1), aspect=15, ax=ax) + cbar = plt.colorbar(cmap, label="variant frequency", pad=0, shrink=n_samples/(min_y_location+n_samples), anchor=(0.1,1), aspect=15, ax=ax) cbar.set_ticks(ticks) cbar.set_ticklabels(labels) -def create_mutation_legend(mutation_set, min_y_location, n_samples, n_scoresets=0): +def create_mutation_legend(mutation_set, min_y_location, n_samples, n_scores): """ create a legend for the mutation type """ @@ -179,11 +146,7 @@ def create_mutation_legend(mutation_set, min_y_location, n_samples, n_scoresets= legend_patches.append(patches.Patch(color="blue", label="INS")) if "SNV" in mutation_set: legend_patches.append(patches.Patch(color="dimgrey", label="SNV")) - - if n_scoresets != 0: - plt.legend(handles=legend_patches, bbox_to_anchor=(1.02, 0.95 - (n_samples / (min_y_location + n_samples))), loc='upper left', ncol=len(legend_patches)) - else: - plt.legend(bbox_to_anchor=(1.01, 0.95-(n_samples/(min_y_location+n_samples))), handles=legend_patches) + plt.legend(bbox_to_anchor=(1.01, 0.95-(n_samples/(min_y_location+n_samples+n_scores))), handles=legend_patches) def create_axis(ax, n_mutations, min_y_location, n_samples, file_names, start, stop, genome_y_location, unique_mutations, reference_name, n_scoresets=0): @@ -193,7 +156,7 @@ def create_axis(ax, n_mutations, min_y_location, n_samples, file_names, start, s # define plot limits ax.set_xlim(0, n_mutations) - ax.set_ylim(-min_y_location - n_scoresets, n_samples) + ax.set_ylim(-min_y_location, n_samples) # define new ticks depending on the genome size axis_length = stop - start if n_mutations >= 20: @@ -230,7 +193,7 @@ def create_axis(ax, n_mutations, min_y_location, n_samples, file_names, start, s ax.spines["left"].set_visible(False) -def create_gene_vis(ax, genes_with_mutations, n_mutations, y_size, n_tracks, start, stop, min_y_location, genome_y_location, colors_genes): +def create_gene_vis(ax, genes_with_mutations, n_mutations, y_size, n_tracks, start, stop, min_y_location, genome_y_location, colors_genes, n_scores): """ create the vis for the gene """ @@ -244,7 +207,7 @@ def create_gene_vis(ax, genes_with_mutations, n_mutations, y_size, n_tracks, sta x_value = 0 else: x_value = mult_factor*(genes_with_mutations[gene][0][0]-start) - y_value = -min_y_location+(n_tracks-genes_with_mutations[gene][1])*genome_y_location/2-genome_y_location/2 + y_value = -min_y_location+(n_tracks+n_scores-genes_with_mutations[gene][1])*genome_y_location/2 if genes_with_mutations[gene][0][1] > stop: width = n_mutations - x_value else: From 3070e110b73ede7cf6858029cc1b1c496370bb8e Mon Sep 17 00:00:00 2001 From: jonas-fuchs Date: Fri, 17 May 2024 14:18:01 +0200 Subject: [PATCH 06/10] reformating and comments --- virheat/command.py | 21 ++++++++++----------- virheat/scripts/plotting.py | 11 +++++------ 2 files changed, 15 insertions(+), 17 deletions(-) diff --git a/virheat/command.py b/virheat/command.py index dd1fcf4..21257a5 100644 --- a/virheat/command.py +++ b/virheat/command.py @@ -224,16 +224,7 @@ def main(sysargs=sys.argv[1:]): unique_mutations, reference_name, n_scores) plotting.create_mutation_legend(mutation_set, min_y_location, n_samples, n_scores) plotting.create_colorbar(args.threshold, cmap_cells, min_y_location, n_samples, ax) - # plot scores as track below the genome track - if args.scores: - score_count = 1 - for score_params in args.scores: - scores_file, pos_col, score_col, score_name = score_params - unique_scores = data_prep.extract_scores(unique_mutations, scores_file, pos_col, score_col) - track_created = plotting.create_scores_vis(ax, genome_y_location, n_mutations, n_tracks, unique_scores, start, stop, score_count, score_name) - if track_created: - score_count += 1 - + # plot gene track if args.gff3_path is not None: if genes_with_mutations: # distinct colors for the genes @@ -241,7 +232,15 @@ def main(sysargs=sys.argv[1:]): colors_genes = [cmap_genes(i) for i in range(len(genes_with_mutations))] # plot gene track plotting.create_gene_vis(ax, genes_with_mutations, n_mutations, y_size, n_tracks, start, stop, min_y_location, genome_y_location, colors_genes, n_scores) - + # plot scores as track below the gene/genome track + if args.scores: + score_count = 1 + for score_params in args.scores: + scores_file, pos_col, score_col, score_name = score_params + unique_scores = data_prep.extract_scores(unique_mutations, scores_file, pos_col, score_col) + track_created = plotting.create_scores_vis(ax, genome_y_location, n_mutations, n_tracks, unique_scores, start, stop, score_count, score_name) + if track_created: # only creates a track if it finds mutations to annotate + score_count += 1 # create output folder if not os.path.exists(args.input[1]): os.makedirs(args.input[1]) diff --git a/virheat/scripts/plotting.py b/virheat/scripts/plotting.py index 9cf4e65..cacc036 100644 --- a/virheat/scripts/plotting.py +++ b/virheat/scripts/plotting.py @@ -9,7 +9,7 @@ # LIBS import matplotlib.pyplot as plt import matplotlib.patches as patches -import matplotlib.colors as mcolors + def create_heatmap(ax, frequency_array, cmap): """ @@ -49,7 +49,6 @@ def create_genome_vis(ax, genome_y_location, n_mutations, unique_mutations, star ec="none", fc="lightgrey" ) ) - # create mutation lines on the genome rectangle and the mapping to the respective cells x_start = 0 length = stop - start @@ -73,7 +72,7 @@ def create_scores_vis(ax, genome_y_location, n_mutations, n_tracks, unique_mutat create the scores rectangles, mappings to the reference """ score_set = [] - y_zero = -genome_y_location - (n_tracks + score_count + 1) * (genome_y_location / 2) + y_zero = -genome_y_location - (n_tracks + score_count + 1) * (genome_y_location / 2) # zero line length = stop - start # create list of tuples [(nt pos, score)] @@ -81,14 +80,13 @@ def create_scores_vis(ax, genome_y_location, n_mutations, n_tracks, unique_mutat mutation_attributes = mutation.split("_") if not np.isnan(float(mutation_attributes[5])): score_set.append((int(mutation_attributes[0]), float(mutation_attributes[5]))) - + # check if there is something to plot if score_set: # create zero line and score name on the left plt.axhline(y=y_zero, color='black', linestyle='-', linewidth=0.5) ax.text(-0.5, y_zero, score_name, ha='right', va='center') - # define normalization multiplier + # define normalization multiplier for the height of the score v lines multiplier = max([abs(score[1]) for score in score_set]) / abs((y_zero + genome_y_location / 4) - y_zero) - # create score lines on the score rectangle and the mapping to the respective mutation lines for score in score_set: # define x value @@ -100,6 +98,7 @@ def create_scores_vis(ax, genome_y_location, n_mutations, n_tracks, unique_mutat else: plt.vlines(x=mutation_x_location, ymin=y_zero, ymax=y_zero + score[1] / multiplier, color="blue", linestyle='-') return True + # if not the track is not created else: print("\033[31m\033[1mERROR:\033[0m Seems like there are no scores in the score set '{}' corresponding to the plotted mutation positions.".format(score_name)) return False From 8dd3ad3714f6c020eaec901a79bd5144151e3cea Mon Sep 17 00:00:00 2001 From: jonas-fuchs Date: Fri, 17 May 2024 14:40:25 +0200 Subject: [PATCH 07/10] changed example data and output --- README.md | 6 +++++- .../output/virHEAT_plot_12samples_1score.pdf | Bin 43566 -> 0 bytes .../output/virHEAT_plot_12samples_2scores.pdf | Bin 45685 -> 0 bytes .../virHEAT_plot_12samples_2scores_zoom.pdf | Bin 30475 -> 0 bytes .../output/virHEAT_plot_3samples_4scores.pdf | Bin 31878 -> 0 bytes .../output/virHEAT_plot_3ssamples2scores.pdf | Bin 28625 -> 0 bytes .../virHEAT_plot_many-samples_4scores.pdf | Bin 89896 -> 0 bytes .../virHEAT_plot_many_samples_6scores.pdf | Bin 397992 -> 0 bytes .../MaveBindRBD.csv | 0 .../input => example_mave_data}/MaveExpRBD.csv | 0 .../SARS-CoV-2.gff3 | 0 example_mave_data/example_scores.png | Bin 0 -> 115395 bytes .../input => example_mave_data}/sample-01.vcf | 0 .../input => example_mave_data}/sample-02.vcf | 0 .../input => example_mave_data}/sample-03.vcf | 0 .../input => example_mave_data}/sample-04.vcf | 0 .../input => example_mave_data}/sample-05.vcf | 0 .../input => example_mave_data}/sample-06.vcf | 0 .../input => example_mave_data}/sample-07.vcf | 0 .../input => example_mave_data}/sample-08.vcf | 0 .../input => example_mave_data}/sample-09.vcf | 0 .../input => example_mave_data}/sample-10.vcf | 0 .../input => example_mave_data}/sample-11.vcf | 0 .../input => example_mave_data}/sample-12.vcf | 0 24 files changed, 5 insertions(+), 1 deletion(-) delete mode 100644 example_data/example_mave_data/output/virHEAT_plot_12samples_1score.pdf delete mode 100644 example_data/example_mave_data/output/virHEAT_plot_12samples_2scores.pdf delete mode 100644 example_data/example_mave_data/output/virHEAT_plot_12samples_2scores_zoom.pdf delete mode 100644 example_data/example_mave_data/output/virHEAT_plot_3samples_4scores.pdf delete mode 100644 example_data/example_mave_data/output/virHEAT_plot_3ssamples2scores.pdf delete mode 100644 example_data/example_mave_data/output/virHEAT_plot_many-samples_4scores.pdf delete mode 100644 example_data/example_mave_data/output/virHEAT_plot_many_samples_6scores.pdf rename {example_data/example_mave_data/input => example_mave_data}/MaveBindRBD.csv (100%) rename {example_data/example_mave_data/input => example_mave_data}/MaveExpRBD.csv (100%) rename {example_data/example_mave_data/input => example_mave_data}/SARS-CoV-2.gff3 (100%) create mode 100644 example_mave_data/example_scores.png rename {example_data/example_mave_data/input => example_mave_data}/sample-01.vcf (100%) rename {example_data/example_mave_data/input => example_mave_data}/sample-02.vcf (100%) rename {example_data/example_mave_data/input => example_mave_data}/sample-03.vcf (100%) rename {example_data/example_mave_data/input => example_mave_data}/sample-04.vcf (100%) rename {example_data/example_mave_data/input => example_mave_data}/sample-05.vcf (100%) rename {example_data/example_mave_data/input => example_mave_data}/sample-06.vcf (100%) rename {example_data/example_mave_data/input => example_mave_data}/sample-07.vcf (100%) rename {example_data/example_mave_data/input => example_mave_data}/sample-08.vcf (100%) rename {example_data/example_mave_data/input => example_mave_data}/sample-09.vcf (100%) rename {example_data/example_mave_data/input => example_mave_data}/sample-10.vcf (100%) rename {example_data/example_mave_data/input => example_mave_data}/sample-11.vcf (100%) rename {example_data/example_mave_data/input => example_mave_data}/sample-12.vcf (100%) diff --git a/README.md b/README.md index cad6a5d..0e25301 100644 --- a/README.md +++ b/README.md @@ -20,6 +20,10 @@ Ever wanted to have a condensed look at variant frequencies after mapping your r ![Example](./example_data/example.png) +## SARS-CoV-2 example with additional score tracks `--scores` + +![Example_Scores](./example_mave_data/example_scores.png) + ## Installation ### via pip (recommened): @@ -90,7 +94,7 @@ Additionally, you can also analyse if mutations are sufficiently covered and dis Moreover, there is an option to include visualizations of additional scores (e.g., MAVE scores for binding affinity, expression level, antibody escape, etc.) mapped to mutations on the heatmap. To utilize this feature, use the -s or --scores argument, and provide the following arguments: 1) path to the CSV file containing scores; 2) the name of the column in this file containing mutation positions in classic notation (e.g., T430Y); 3) the name of the column in this file containing the scores themselves; 4) a descriptive score name that will be used as labels in the plot. Multiple score sets can be included simultaneously by repeating the -s or --scores option with different arguments. For example input and possible output data, -please refer to the files located in the [example_data/example_mave_data](./example_data/example_mave_data) folder. +please refer to the files located in the [example_data/example_mave_data](example_mave_data) folder. --- diff --git a/example_data/example_mave_data/output/virHEAT_plot_12samples_1score.pdf b/example_data/example_mave_data/output/virHEAT_plot_12samples_1score.pdf deleted file mode 100644 index 9a30862e96229b42d364fe38d4af36044efc6c71..0000000000000000000000000000000000000000 GIT binary patch literal 0 HcmV?d00001 literal 43566 zcmb4r2Rzna|945E$S#zr#psBeA0ThdgfNfOnj<(#)fy91fatuCJBlChL*RGj;H@IK-S9AmPrup zz;{hW|F)rlEt3fL@w}t0++|xmTSF!xtU*=J*4EI*l1Ui(xS#K`iQX+!OJk-}JKx$^ z8C*8BWx5V(Wn{q=Lq}UCJ_QRf0k`x2(mVgJz@+^TbNK&n2N1gv>un6dI?Q~&ONMu? z>}(9cAH;spuVi@3R1at62pUhqfB4Uw65$m%b%tL=gh@nDg!h!N(3w+$fbG#s>NNcQ7v+S{mD$F!ApgAZuz4?lbYpnnO%v3=OPq z86sZXwY4$Sv)J#LFj=7(cD%vvso1h^gtYY=E)PiphjWLXdLN?0lV`9cr3*RGe<^~+ 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diff --git a/example_data/example_mave_data/input/sample-01.vcf b/example_mave_data/sample-01.vcf similarity index 100% rename from example_data/example_mave_data/input/sample-01.vcf rename to example_mave_data/sample-01.vcf diff --git a/example_data/example_mave_data/input/sample-02.vcf b/example_mave_data/sample-02.vcf similarity index 100% rename from example_data/example_mave_data/input/sample-02.vcf rename to example_mave_data/sample-02.vcf diff --git a/example_data/example_mave_data/input/sample-03.vcf b/example_mave_data/sample-03.vcf similarity index 100% rename from example_data/example_mave_data/input/sample-03.vcf rename to example_mave_data/sample-03.vcf diff --git a/example_data/example_mave_data/input/sample-04.vcf b/example_mave_data/sample-04.vcf similarity index 100% rename from example_data/example_mave_data/input/sample-04.vcf rename to example_mave_data/sample-04.vcf diff --git a/example_data/example_mave_data/input/sample-05.vcf b/example_mave_data/sample-05.vcf similarity index 100% rename from example_data/example_mave_data/input/sample-05.vcf rename to example_mave_data/sample-05.vcf diff --git a/example_data/example_mave_data/input/sample-06.vcf b/example_mave_data/sample-06.vcf similarity index 100% rename from example_data/example_mave_data/input/sample-06.vcf rename to example_mave_data/sample-06.vcf diff --git a/example_data/example_mave_data/input/sample-07.vcf b/example_mave_data/sample-07.vcf similarity index 100% rename from example_data/example_mave_data/input/sample-07.vcf rename to example_mave_data/sample-07.vcf diff --git a/example_data/example_mave_data/input/sample-08.vcf b/example_mave_data/sample-08.vcf similarity index 100% rename from example_data/example_mave_data/input/sample-08.vcf rename to example_mave_data/sample-08.vcf diff --git a/example_data/example_mave_data/input/sample-09.vcf b/example_mave_data/sample-09.vcf similarity index 100% rename from example_data/example_mave_data/input/sample-09.vcf rename to example_mave_data/sample-09.vcf diff --git a/example_data/example_mave_data/input/sample-10.vcf b/example_mave_data/sample-10.vcf similarity index 100% rename from example_data/example_mave_data/input/sample-10.vcf rename to example_mave_data/sample-10.vcf diff --git a/example_data/example_mave_data/input/sample-11.vcf b/example_mave_data/sample-11.vcf similarity index 100% rename from example_data/example_mave_data/input/sample-11.vcf rename to example_mave_data/sample-11.vcf diff --git a/example_data/example_mave_data/input/sample-12.vcf b/example_mave_data/sample-12.vcf similarity index 100% rename from example_data/example_mave_data/input/sample-12.vcf rename to example_mave_data/sample-12.vcf From 76c174d0718cae9abfbc18b5d67d8c139cb6d956 Mon Sep 17 00:00:00 2001 From: jonas-fuchs Date: Fri, 17 May 2024 17:24:12 +0200 Subject: [PATCH 08/10] added score boundaries and scale --- example_mave_data/example_scores.png | Bin 115395 -> 120328 bytes virheat/command.py | 2 +- 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a/virheat/command.py b/virheat/command.py index 21257a5..0b3c1f7 100644 --- a/virheat/command.py +++ b/virheat/command.py @@ -221,7 +221,7 @@ def main(sysargs=sys.argv[1:]): plotting.create_heatmap(ax, frequency_array, cmap_cells) mutation_set = plotting.create_genome_vis(ax, genome_y_location, n_mutations, unique_mutations, start, stop) plotting.create_axis(ax, n_mutations, min_y_location, n_samples, file_names, start, stop, genome_y_location, - unique_mutations, reference_name, n_scores) + unique_mutations, reference_name) plotting.create_mutation_legend(mutation_set, min_y_location, n_samples, n_scores) plotting.create_colorbar(args.threshold, cmap_cells, min_y_location, n_samples, ax) # plot gene track diff --git a/virheat/scripts/plotting.py b/virheat/scripts/plotting.py index cacc036..34b1fa9 100644 --- a/virheat/scripts/plotting.py +++ b/virheat/scripts/plotting.py @@ -82,21 +82,39 @@ def create_scores_vis(ax, genome_y_location, n_mutations, n_tracks, unique_mutat score_set.append((int(mutation_attributes[0]), float(mutation_attributes[5]))) # check if there is something to plot if score_set: - # create zero line and score name on the left - plt.axhline(y=y_zero, color='black', linestyle='-', linewidth=0.5) - ax.text(-0.5, y_zero, score_name, ha='right', va='center') # define normalization multiplier for the height of the score v lines - multiplier = max([abs(score[1]) for score in score_set]) / abs((y_zero + genome_y_location / 4) - y_zero) - # create score lines on the score rectangle and the mapping to the respective mutation lines + max_value = max([abs(score[1]) for score in score_set]) # max abs in score set + multiplier = max_value / abs((y_zero + genome_y_location / 4) - y_zero) + # add text for scale and score_name + if score_count % 2 == 0: + score_name_loc, scale_loc, vline_loc = ax.get_xlim()[1] + 0.5, ax.get_xlim()[0] - 0.5, ax.get_xlim()[0] + name_ha_aln, scale_ha_aln = "left", "right" + else: + score_name_loc, scale_loc, vline_loc = ax.get_xlim()[0] - 0.5, ax.get_xlim()[1] + 0.5, ax.get_xlim()[1] + name_ha_aln, scale_ha_aln = "right", "left" + # score name + ax.text(score_name_loc, y_zero, score_name, ha=name_ha_aln, va='center') + # scale + ax.text(scale_loc, y_zero, "0", ha=scale_ha_aln, va='center') + ax.text(scale_loc, y_zero - genome_y_location / 4, -max_value, ha=scale_ha_aln, va='center', color='red') + ax.text(scale_loc, y_zero + genome_y_location / 4, max_value, ha=scale_ha_aln, va='center', color='blue') + plt.vlines(x=vline_loc, ymin=y_zero - genome_y_location / 4, ymax=y_zero + genome_y_location / 4, color='black', linewidth=2) + # add h line boundaries for scale + if score_count is 1: + plt.axhline(y=y_zero + genome_y_location / 4, color='grey', linestyle='--', linewidth=0.5) + plt.axhline(y=y_zero - genome_y_location / 4, color='grey', linestyle='--', linewidth=0.5) + # create zero line + plt.axhline(y=y_zero, color='black', linestyle='-', linewidth=0.5) + # create bars for scores for score in score_set: # define x value mutation_x_location = n_mutations / length * (score[0] - start) - # define y value # create lines for score_set if score[1] < 0: plt.vlines(x=mutation_x_location, ymin=y_zero + score[1]/multiplier, ymax=y_zero, color="red", linestyle='-') else: plt.vlines(x=mutation_x_location, ymin=y_zero, ymax=y_zero + score[1] / multiplier, color="blue", linestyle='-') + return True # if not the track is not created else: @@ -148,7 +166,7 @@ def create_mutation_legend(mutation_set, min_y_location, n_samples, n_scores): plt.legend(bbox_to_anchor=(1.01, 0.95-(n_samples/(min_y_location+n_samples+n_scores))), handles=legend_patches) -def create_axis(ax, n_mutations, min_y_location, n_samples, file_names, start, stop, genome_y_location, unique_mutations, reference_name, n_scoresets=0): +def create_axis(ax, n_mutations, min_y_location, n_samples, file_names, start, stop, genome_y_location, unique_mutations, reference_name): """ create the axis of the plot """ From a2376b63a1ba26abc2e6c9fc8fdaff44067ba5ec Mon Sep 17 00:00:00 2001 From: PlushZ Date: Tue, 21 May 2024 15:25:25 +0200 Subject: [PATCH 09/10] handle empty vcfs --- virheat/command.py | 12 ++++++++---- 1 file changed, 8 insertions(+), 4 deletions(-) diff --git a/virheat/command.py b/virheat/command.py index 0b3c1f7..9f107af 100644 --- a/virheat/command.py +++ b/virheat/command.py @@ -143,11 +143,15 @@ def main(sysargs=sys.argv[1:]): # extract vcf info n_scores = 0 - if args.scores: - reference_name, frequency_lists, unique_mutations, file_names = data_prep.extract_vcf_data(vcf_files, threshold=args.threshold, scores=True) - n_scores = len(args.scores) + if not vcf_files: + sys.exit("\033[31m\033[1mERROR:\033[0m No VCF files provided") else: - reference_name, frequency_lists, unique_mutations, file_names = data_prep.extract_vcf_data(vcf_files, threshold=args.threshold) + if args.scores: + reference_name, frequency_lists, unique_mutations, file_names = data_prep.extract_vcf_data(vcf_files, threshold=args.threshold, scores=True) + n_scores = len(args.scores) + else: + reference_name, frequency_lists, unique_mutations, file_names = data_prep.extract_vcf_data(vcf_files, threshold=args.threshold) + if args.zoom: unique_mutations = data_prep.zoom_to_genomic_regions(unique_mutations, args.zoom) frequency_array = data_prep.create_freq_array(unique_mutations, frequency_lists) From 31132d2a3fc76fd30c5cd58efa6bec1083cebae3 Mon Sep 17 00:00:00 2001 From: PlushZ Date: Tue, 21 May 2024 15:49:11 +0200 Subject: [PATCH 10/10] warning if empty vcf header --- virheat/scripts/data_prep.py | 6 +++++- 1 file changed, 5 insertions(+), 1 deletion(-) diff --git a/virheat/scripts/data_prep.py b/virheat/scripts/data_prep.py index af1c957..4cf64a1 100644 --- a/virheat/scripts/data_prep.py +++ b/virheat/scripts/data_prep.py @@ -55,7 +55,11 @@ def read_vcf(vcf_file): # get header and values with open(vcf_file, "r") as f: - header = [l.split("\t") for l in f if l.startswith('#CHROM')][0] + header_lines = [l.split("\t") for l in f if l.startswith('#CHROM')] + if not header_lines: + print(f"\033[31m\033[1mWARNING:\033[0m {vcf_file} does not contain a '#CHROM' header!") + return {} + header = header_lines[0] # get each line as frequency_lists with open(vcf_file, "r") as f: lines = [l.split("\t") for l in f if not l.startswith('#')]