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PZ node is not active #3

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nana-zhang opened this issue Mar 4, 2022 · 1 comment
Open

PZ node is not active #3

nana-zhang opened this issue Mar 4, 2022 · 1 comment

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@nana-zhang
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Hello, I'm trying to use BVEP. I use the brain imaging data of our own epilepsy patients and generate the structural connection matrix by running tvb- recon. Then I try to use the structural connection matrix for forward simulation. I run two codes, BVEP/ TVB / forwardsimulation_ VEPmodel_ patient1. Ipynb and BVEP / TVB / forwarssimulation_ VEPmodel_ SEEG_ patient1. Ipynb, as in the code, set nodes 6 and 34 as EZ, 5, 11 and 27 as PZ, and the rest as Hz. However, I found that the result only shows that EZ node is active, and no PZ node is responding. What is the reason? Is it related to the patient's connection matrix? Is this a normal phenomenon?
Screenshot from 2022-03-04 18-26-24
Screenshot from 2022-03-04 20-05-35

@mhashemi0873
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mhashemi0873 commented Apr 7, 2022

The propagation needs strong coupling K and dramatically depends on the structural connectivity (SC) matrix, as well as excitability value. One solution is to increase coupling K, or increase the excitability value for these nodes closer to the critical value -2.05. A simpler way is to increase coupling between EZ and PZ, according to the clinical hypothesis.

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