gorule-0000007.md

layout	id	title	type	contact	status	fail_mode	implementations
rule	GORULE:0000007	IPI should not be used with GO:0003824 catalytic activity or descendents	report	[email protected]	implemented	soft	language code sparql PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#> PREFIX owl: <http://www.w3.org/2002/07/owl#> PREFIX RO: <http://purl.obolibrary.org/obo/RO_> PREFIX hasEvidence: <http://purl.obolibrary.org/obo/RO_0002612> PREFIX ECO: <http://purl.obolibrary.org/obo/ECO_> PREFIX GO: <http://purl.obolibrary.org/obo/GO_> PREFIX catalytic_activity: <http://purl.obolibrary.org/obo/GO_0003824> PREFIX IPI: <http://purl.obolibrary.org/obo/ECO_0000353> PREFIX metago: <http://model.geneontology.org/> SELECT ?subj ?relation ?object ?s ?evidence WHERE { GRAPH ?g { ?g metago:graphType metago:gafCam . ?s hasEvidence: ?evidence . ?evidence a IPI: . ?s owl:annotatedSource ?subj . ?s owl:annotatedProperty ?relation . ?s owl:annotatedTarget ?object . ?subj ?relation ?object . ?subj a ?iclass . ?object a catalytic_activity: . FILTER (?iclass != owl:NamedIndividual) # There should be no results where instances of # 'catalytic_activity molecular function' ; GO:0003824 also have evidences of IPI } } LIMIT 100

Evidence from a binary interaction (IPI - Inferred from Physical Interaction evidence code) is considered too weak to support an annotation to catalytic activity ; GO:0003824 or children. These annotations are flagged and should be reviewed.