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GO:0006302 | double-strand break repair | IBA with PTN000234048 , S000005667 #5569

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ValWood opened this issue Dec 3, 2024 · 1 comment
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@ValWood
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ValWood commented Dec 3, 2024

  • PTHR ID & PTN node:

GO:0006302 | double-strand break repair | IBA with PTN000234048 , S000005667

  • Sequences with problematic annotation (ID + gene/protein name):

https://www.pombase.org/gene/SPAC664.02c

  • Type of Issue: Erroneous source or erroneous propagation, or other issue

I amnnotated to
DNA repair-dependent chromatin remodeling
rather than direct involvement in DNA damage repeat.

@pgaudet do you agree?

  • Add the label 'high priority' if needed. Generally high priority issues affect a lot of proteins, and annotations are incorrect (as opposed to just imprecise).
@ValWood
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ValWood commented Dec 3, 2024

actually I remember I looked at this recently.
Another Ino80 subunit nhp10 has
Non-essential INO80 chromatin remodeling complex subunit; preferentially binds DNA ends, protecting them from exonucleatic cleavage; deletion affects telomere maintenance via recombination; related to mammalian high mobility group proteins 2 [3]

so maybe this is a bit more direct.

will leave this one

@ValWood ValWood closed this as completed Dec 3, 2024
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