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IPR013328 6-phosphogluconate dehydrogenase, domain 2 #4875

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sjm41 opened this issue Dec 15, 2023 · 1 comment
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IPR013328 6-phosphogluconate dehydrogenase, domain 2 #4875

sjm41 opened this issue Dec 15, 2023 · 1 comment

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@sjm41
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sjm41 commented Dec 15, 2023

  • InterPro ID / label
    IPR013328 6-phosphogluconate dehydrogenase, domain 2

  • Example sequences with problematic annotation (ID + gene/protein name):
    Dmel Ndf (Q8T079)
    Human GLYR1 (Q49A26)

  • Description of issue
    This homologous superfamily entry is annotated with the high-level MF term 'oxidoreductase activity', but the signature is found in Ndf/GLYR1, which is not characterised to be an enzyme.
    Suggest removing this association.

@blazaropinto
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Hi Steven,

Thank you so much for this. This entry also represents a domain with NADP/binding activity in many proteins. This term is removed now. The changes will be available in the next InterPro release.

Best,

Beatriz

@sjm41 sjm41 closed this as completed Dec 18, 2023
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