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PTN000897517 false positive for cytosolic ribosome #4787

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ValWood opened this issue Oct 20, 2023 · 3 comments
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PTN000897517 false positive for cytosolic ribosome #4787

ValWood opened this issue Oct 20, 2023 · 3 comments
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@ValWood
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ValWood commented Oct 20, 2023

  • PTHR ID & PTN node:

IBA with S000006119 , MGI:98073 , P18124 , PTN000897517 , 735169 , S000003044

  • Sequences with problematic annotation (ID + gene/protein name):

https://www.pombase.org/gene/SPBC18H10.12c

  • Type of Issue: Erroneous source or erroneous propagation, or other issue

One member of this family isn't a ribosomal protein its a n
MRP subunit

  • Add the label 'high priority' if needed. Generally high priority issues affect a lot of proteins, and annotations are incorrect (as opposed to just imprecise).
@ValWood
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ValWood commented Oct 20, 2023

I might need to look into this. I thought it was a different ribosomal subunit. I don't know if this is correct in PomBase.

@ValWood ValWood self-assigned this Oct 20, 2023
@ValWood
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ValWood commented Oct 29, 2023

It's definitley incorrect for this one.
https://www.pombase.org/gene/SPBC18H10.12c

This family is going to be tricky:
https://www.pombase.org/gene_subset/interpro:IPR012988
I don't know if this will resolve..

@marcfeuermann
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Okay, for the moment I blocked annotation to rpl701 and rpl702. The family topology is confusing here with 3 S. pombe and S. japonicus sequences clustered together. Could be changed in the future.

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