results_in_development_of.md

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results_in_development_of

• OWL ID: RO_0002296
• label: results in development of
• synonyms []

Definition

p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state.

Usage

The relationship linking an entity and its participation in a process that changes it through time from the formation of the entity to the resultant mature state.

Comment

Example of use: an annotation of gene X to cell development with results_in_development_of CL:0000540 (neuron) means that gene x is involved in a process where a cell that has an identity of a neuron has gone through a progression from its formation to the resulting mature neuron.

Subsets

[valid_for_annotation_extension, AE_cell_or_anatomical, AE_cellular_component, display_for_curators]

##local domain {u'BFO:0000015': u'process'}

local range

{u'CL:0000000': u'cell', u'GO:0005575': u'cellular_component', u'UBERON:0001062': u'anatomical entity', u'PO:0025131': u'plant anatomical entity', u'WBbt:0004017': u'Cell', u'WBbt:0005766': u'Anatomy'}

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Annotation Extension Usage Examples

Enhancing Molecular Function and Biological Process Annotations

Specifying the cell or tissue type which are under going the developmental process

1. Development of a particular tissue:

Statement from paper:

Periostin is critically required for maintenance of the integrity of the periodontal ligament..

Gene Name (col 2)	GO ID (col 5)	Reference (col 6)	Evidence (col 7)	Annotation Extension (col 16)
MGI:1926321 Postn	GO:0009888 tissue development	PMID:16314533	IMP	results_in_development_of(MA:0002467) periodontal ligament

Using examples (from above) to demonstrate Folding_and_Unfolding using the relationship results_in_development_of

1. Differentiation of a particular cell type:

Folded/unfolded	Gene Name (col 2)	GO ID (col 5)	Reference (col 6)	Evidence (col 7)	Annotation Extension (col 16)	Parent terms of new folded GO term
Unfolded	MGI:1926321 Postn	GO:0009888 tissue development	PMID:16314533	IMP	results_in_development_of(CL:0000540) neuron
Folded	MGI:1926321 Postn	New GO ID: periodontal ligament development	PMID:16314533	IMP		is_a GO:0009888 tissue development

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