diff --git a/src/main/scala/com/fulcrumgenomics/sv/tools/SvPileup.scala b/src/main/scala/com/fulcrumgenomics/sv/tools/SvPileup.scala
index f74dd59..b04603e 100644
--- a/src/main/scala/com/fulcrumgenomics/sv/tools/SvPileup.scala
+++ b/src/main/scala/com/fulcrumgenomics/sv/tools/SvPileup.scala
@@ -122,7 +122,8 @@ class SvPileup
    |side of an aligned segment when merging segments.""") slop: Int = 5,
  @arg(flag='t', doc="Optional bed file of target regions") targetsBed: Option[FilePath] = None,
  @arg(flag='T', doc="Requirement on if each side of the breakpoint must overlap a target.  Will always annotate each side of the breakpoint.")
- targetsBedRequirement: TargetBedRequirement.Requirement = TargetBedRequirement.AnnotateOnly
+ targetsBedRequirement: TargetBedRequirement.Requirement = TargetBedRequirement.AnnotateOnly,
+ @arg(doc="Whether to include duplicate marked records in the pileup or not.") val includeDuplicates: Boolean = false
 ) extends SvTool {
 
   import SvPileup._
@@ -145,7 +146,14 @@ class SvPileup
 
     Bams.templateIterator(source)
       .tapEach(t => progress.record(t.allReads.next()))
-      .flatMap(template => filterTemplate(template, minPrimaryMapq=minPrimaryMappingQuality, minSupplementaryMapq=minSupplementaryMappingQuality))
+      .flatMap { template =>
+        filterTemplate(
+          template,
+          minPrimaryMapq=minPrimaryMappingQuality,
+          minSupplementaryMapq=minSupplementaryMappingQuality,
+          includeDuplicates=includeDuplicates,
+        )
+      }
       .foreach { template =>
         // Find the breakpoints
         val evidences = findBreakpoints(
@@ -297,18 +305,24 @@ object SvPileup extends LazyLogging {
    */
   def filterTemplate(t: Template,
                      minPrimaryMapq: Int,
-                     minSupplementaryMapq: Int): Option[Template] = {
-    val r1PrimaryOk = t.r1.exists(r => r.mapped && r.mapq >= minPrimaryMapq)
-    val r2PrimaryOk = t.r2.exists(r => r.mapped && r.mapq >= minPrimaryMapq)
-
-    if (!r1PrimaryOk && !r2PrimaryOk) None else Some(
-      Template(
-        r1              = if (r1PrimaryOk) t.r1 else None,
-        r2              = if (r2PrimaryOk) t.r2 else None,
-        r1Supplementals = if (r1PrimaryOk) t.r1Supplementals.filter(_.mapq >= minSupplementaryMapq) else Nil,
-        r2Supplementals = if (r2PrimaryOk) t.r2Supplementals.filter(_.mapq >= minSupplementaryMapq) else Nil,
-      )
-    )
+                     minSupplementaryMapq: Int,
+                     includeDuplicates: Boolean = false): Option[Template] = {
+    t.allReads.filter(rec => includeDuplicates || !rec.duplicate).toList match {
+      case Nil     => None
+      case records =>
+        val duplicateFiltered = Template(records.iterator)
+        val r1PrimaryOk = duplicateFiltered.r1.exists(r => r.mapped && r.mapq >= minPrimaryMapq)
+        val r2PrimaryOk = duplicateFiltered.r2.exists(r => r.mapped && r.mapq >= minPrimaryMapq)
+
+        if (!r1PrimaryOk && !r2PrimaryOk) None else Some(
+          Template(
+            r1              = if (r1PrimaryOk) duplicateFiltered.r1 else None,
+            r2              = if (r2PrimaryOk) duplicateFiltered.r2 else None,
+            r1Supplementals = if (r1PrimaryOk) duplicateFiltered.r1Supplementals.filter(_.mapq >= minSupplementaryMapq) else Nil,
+            r2Supplementals = if (r2PrimaryOk) duplicateFiltered.r2Supplementals.filter(_.mapq >= minSupplementaryMapq) else Nil,
+          )
+        )
+    }
   }
 
 
diff --git a/src/test/scala/com/fulcrumgenomics/sv/tools/SvPileupTest.scala b/src/test/scala/com/fulcrumgenomics/sv/tools/SvPileupTest.scala
index 1597c91..9aee4e7 100644
--- a/src/test/scala/com/fulcrumgenomics/sv/tools/SvPileupTest.scala
+++ b/src/test/scala/com/fulcrumgenomics/sv/tools/SvPileupTest.scala
@@ -420,6 +420,94 @@ class SvPileupTest extends UnitSpec {
     SvPileup.filterTemplate(template, minPrimaryMapq=30, minSupplementaryMapq=20) shouldBe None
   }
 
+  it should s"ignore records for the entire ordinal where R1 (true) or R2 (false) are marked as duplicates" in {
+    val r1 = r("chr1", 100, Plus, r = 1, cigar = "100M", supp = false, mapq = 50)
+    val r2 = r("chr1", 300, Plus, r = 2, cigar = "100M", supp = false, mapq = 50)
+    val r1supp = r("chr7", 800, Plus,  r=1, cigar="50S50M", supp=true,  mapq=50)
+    val r2supp = r("chr7", 800, Plus,  r=2, cigar="50S50M", supp=true,  mapq=50)
+
+    val template = t(r1, r2, r1supp, r2supp)
+
+    SvPileup.filterTemplate(template, minPrimaryMapq = 30, minSupplementaryMapq = 20).value shouldBe template
+
+    r1.duplicate = true
+    r2.duplicate = false
+
+    val expected = template.copy(r1=None, r1Supplementals = Nil, r1Secondaries = Nil)
+
+    SvPileup.filterTemplate(template, minPrimaryMapq = 30, minSupplementaryMapq = 20).value shouldBe expected
+  }
+
+  it should s"ignore records for the entire ordinal where R1 (false) or R2 (true) are marked as duplicates" in {
+    val r1 = r("chr1", 100, Plus, r = 1, cigar = "100M", supp = false, mapq = 50)
+    val r2 = r("chr1", 300, Plus, r = 2, cigar = "100M", supp = false, mapq = 50)
+    val r1supp = r("chr7", 800, Plus,  r=1, cigar="50S50M", supp=true,  mapq=50)
+    val r2supp = r("chr7", 800, Plus,  r=2, cigar="50S50M", supp=true,  mapq=50)
+
+    val template = t(r1, r2, r1supp, r2supp)
+
+    SvPileup.filterTemplate(template, minPrimaryMapq = 30, minSupplementaryMapq = 20).value shouldBe template
+
+    r1.duplicate = false
+    r2.duplicate = true
+
+    val expected = template.copy(r2=None, r2Supplementals = Nil, r2Secondaries = Nil)
+
+    SvPileup.filterTemplate(template, minPrimaryMapq = 30, minSupplementaryMapq = 20).value shouldBe expected
+  }
+
+  it should s"ignore all records where R1 (true) or R2 (true) are both marked as duplicates" in {
+    val r1 = r("chr1", 100, Plus, r = 1, cigar = "100M", supp = false, mapq = 50)
+    val r2 = r("chr1", 300, Plus, r = 2, cigar = "100M", supp = false, mapq = 50)
+    val r1supp = r("chr7", 800, Plus,  r=1, cigar="50S50M", supp=true,  mapq=50)
+    val r2supp = r("chr7", 800, Plus,  r=2, cigar="50S50M", supp=true,  mapq=50)
+
+    val template = t(r1, r2, r1supp, r2supp)
+
+    SvPileup.filterTemplate(template, minPrimaryMapq = 30, minSupplementaryMapq = 20).value shouldBe template
+
+    r1.duplicate = true
+    r2.duplicate = true
+
+    SvPileup.filterTemplate(template, minPrimaryMapq = 30, minSupplementaryMapq = 20) shouldBe None
+  }
+
+  it should "ignore duplicate supplementals when asked to" in {
+    val r1 = r("chr1", 100, Plus, r = 1, cigar = "100M", supp = false, mapq = 50)
+    val r2 = r("chr1", 300, Plus, r = 2, cigar = "100M", supp = false, mapq = 50)
+    val r1supp = r("chr1", 100, Plus, r = 1, cigar = "100M", supp = true, mapq = 50)
+    val r2supp = r("chr1", 300, Plus, r = 2, cigar = "100M", supp = true, mapq = 50)
+
+    val template = t(r1, r2, r1supp, r2supp)
+
+    SvPileup.filterTemplate(template, minPrimaryMapq = 30, minSupplementaryMapq = 20).value shouldBe template
+
+    r1supp.duplicate = true
+    r2supp.duplicate = true
+
+    val expected = t(r1, r2)
+
+    SvPileup.filterTemplate(template, minPrimaryMapq = 30, minSupplementaryMapq = 20).value shouldBe expected
+  }
+
+  it should "not ignore duplicate records when asked to" in {
+    val r1 = r("chr1", 100, Plus, r = 1, cigar = "100M", supp = false, mapq = 50)
+    val r2 = r("chr1", 300, Plus, r = 2, cigar = "100M", supp = false, mapq = 50)
+    val r1supp = r("chr1", 100, Plus, r = 1, cigar = "100M", supp = true, mapq = 50)
+    val r2supp = r("chr1", 300, Plus, r = 2, cigar = "100M", supp = true, mapq = 50)
+
+    val template = t(r1, r2, r1supp, r2supp)
+
+    SvPileup.filterTemplate(template, minPrimaryMapq = 30, minSupplementaryMapq = 20, includeDuplicates = true).value shouldBe template
+
+    r1.duplicate = true
+    r2.duplicate = true
+    r1supp.duplicate = true
+    r2supp.duplicate = true
+
+    SvPileup.filterTemplate(template, minPrimaryMapq = 30, minSupplementaryMapq = 20, includeDuplicates = true).value shouldBe template
+  }
+
   /** Writes the given BAM records to a BAM file */
   private def toInput(rec: SamRecord*): PathToBam = {
     val path    = makeTempFile("input.", ".bam")