diff --git a/.azure-pipelines/azure-pipelines.yml b/.azure-pipelines/azure-pipelines.yml
index 0158777..d6df28f 100644
--- a/.azure-pipelines/azure-pipelines.yml
+++ b/.azure-pipelines/azure-pipelines.yml
@@ -7,36 +7,6 @@ stages:
     pool:
       vmImage: ubuntu-20.04
     steps:
-      # Run syntax validation using oldest and latest Python
-      - task: UsePythonVersion@0
-        displayName: Set up python
-        inputs:
-          versionSpec: 3.8
-
-      - bash: python .azure-pipelines/syntax-validation.py
-        displayName: Syntax validation (3.7)
-
-      - task: UsePythonVersion@0
-        displayName: Set up python
-        inputs:
-          versionSpec: 3.11
-
-      - bash: python .azure-pipelines/syntax-validation.py
-        displayName: Syntax validation (3.10)
-
-      - bash: |
-          set -eux
-          pip install --disable-pip-version-check ruff
-          python .azure-pipelines/ruff-validation.py
-        displayName: Ruff validation
-
-      - bash: |
-          set -eux
-          # install versions matching the ones in the corresponding pre-commit hook
-          pip install --disable-pip-version-check mypy==1.9.0 types-PyYAML==6.0.12 types-requests==2.31.0
-          mypy --no-strict-optional dials_data/
-        displayName: Type checking
-
       # Set up constants for further build steps
       - bash: |
           echo "##vso[task.setvariable variable=BUILD_REPOSITORY_NAME;isOutput=true]${BUILD_REPOSITORY_NAME}"
@@ -157,14 +127,15 @@ stages:
       vmImage: ubuntu-20.04
     strategy:
       matrix:
-        python38:
-          PYTHON_VERSION: 3.8
         python39:
           PYTHON_VERSION: 3.9
         python310:
           PYTHON_VERSION: 3.10
         python311:
           PYTHON_VERSION: 3.11
+        python312:
+          PYTHON_VERSION: 3.12
+
     steps:
     - template: ci.yml
   - job: macOS
@@ -172,14 +143,15 @@ stages:
       vmImage: macOS-latest
     strategy:
       matrix:
-        python38:
-          PYTHON_VERSION: 3.8
         python39:
           PYTHON_VERSION: 3.9
         python310:
           PYTHON_VERSION: 3.10
         python311:
           PYTHON_VERSION: 3.11
+        python312:
+          PYTHON_VERSION: 3.12
+
     steps:
     - template: ci.yml
   - job: windows
@@ -187,14 +159,15 @@ stages:
       vmImage: windows-latest
     strategy:
       matrix:
-        python38:
-          PYTHON_VERSION: 3.8
         python39:
           PYTHON_VERSION: 3.9
         python310:
           PYTHON_VERSION: 3.10
         python311:
           PYTHON_VERSION: 3.11
+        python312:
+          PYTHON_VERSION: 3.12
+
     steps:
     - template: ci-windows.yml
 
@@ -205,7 +178,7 @@ stages:
   - tests
   condition: and(succeeded(),
                  eq(dependencies.static.outputs['checks.constants.BUILD_REPOSITORY_NAME'], 'dials/data'),
-                 eq(dependencies.static.outputs['checks.constants.BUILD_SOURCEBRANCH'], 'refs/heads/master'))
+                 eq(dependencies.static.outputs['checks.constants.BUILD_SOURCEBRANCH'], 'refs/heads/main'))
   jobs:
   - job: pypi
     displayName: Publish pypi release
@@ -247,7 +220,7 @@ stages:
   - build
   - tests
   condition: and(succeeded(),
-                 eq(dependencies.static.outputs['checks.constants.BUILD_SOURCEBRANCH'], 'refs/heads/master'),
+                 eq(dependencies.static.outputs['checks.constants.BUILD_SOURCEBRANCH'], 'refs/heads/main'),
                  eq(dependencies.static.outputs['checks.constants.BUILD_REPOSITORY_NAME'], 'dials/data'))
              # only run this job in the main branch of the main repository
   jobs:
diff --git a/.azure-pipelines/create-hashinfo-pull-requests b/.azure-pipelines/create-hashinfo-pull-requests
index ce81773..8ea5650 100755
--- a/.azure-pipelines/create-hashinfo-pull-requests
+++ b/.azure-pipelines/create-hashinfo-pull-requests
@@ -17,7 +17,7 @@ echo
 
 echo "##[section]Open pull requests:"
 declare -A UPDATEBRANCHES
-for BRANCH in $(hub pr list -b master -f '%H%n'); do
+for BRANCH in $(hub pr list -b main -f '%H%n'); do
   echo ${BRANCH}
   UPDATEBRANCHES[${BRANCH}]=1
 done
diff --git a/.azure-pipelines/ruff-validation.py b/.azure-pipelines/ruff-validation.py
deleted file mode 100644
index 907217b..0000000
--- a/.azure-pipelines/ruff-validation.py
+++ /dev/null
@@ -1,39 +0,0 @@
-from __future__ import annotations
-
-import subprocess
-import json
-
-failures = 0
-try:
-    output = subprocess.run(
-        ["ruff", "check", "--exit-zero", "--output-format", "json", "."],
-        capture_output=True,
-        check=True,
-        timeout=300,
-    )
-except (subprocess.CalledProcessError, subprocess.TimeoutExpired) as e:
-    print(
-        "##vso[task.logissue type=error;]ruff validation failed with",
-        str(e.__class__.__name__),
-    )
-    print(e.stdout)
-    print(e.stderr)
-    print("##vso[task.complete result=Failed;]ruff validation failed")
-    exit()
-
-results = json.loads(output.stdout)
-
-for violation in results:
-    # filename, lineno, column, error = line.split(":", maxsplit=3)
-    # errcode, error = error.strip().split(" ", maxsplit=1)
-    # filename = os.path.normpath(filename)
-    failures += 1
-    print(
-        f"##vso[task.logissue type=error;sourcepath={violation['filename']};"
-        f"linenumber={violation['location']['row']};columnnumber={violation['location']['column']};code={violation['code']};]"
-        + violation["message"]
-    )
-
-if failures:
-    print(f"##vso[task.logissue type=warning]Found {failures} ruff violation(s)")
-    print(f"##vso[task.complete result=Failed;]Found {failures} ruff violation(s)")
diff --git a/.azure-pipelines/syntax-validation.py b/.azure-pipelines/syntax-validation.py
deleted file mode 100644
index 2d74948..0000000
--- a/.azure-pipelines/syntax-validation.py
+++ /dev/null
@@ -1,32 +0,0 @@
-from __future__ import annotations
-
-import ast
-import os
-import sys
-
-print("Python", sys.version, "\n")
-
-failures = 0
-
-for base, _, files in os.walk("."):
-    for f in files:
-        if not f.endswith(".py"):
-            continue
-        filename = os.path.normpath(os.path.join(base, f))
-        try:
-            with open(filename) as fh:
-                ast.parse(fh.read())
-        except SyntaxError as se:
-            failures += 1
-            print(
-                f"##vso[task.logissue type=error;sourcepath={filename};"
-                f"linenumber={se.lineno};columnnumber={se.offset};]"
-                f"SyntaxError: {se.msg}"
-            )
-            print(" " + se.text + " " * se.offset + "^")
-            print(f"SyntaxError: {se.msg} in {filename} line {se.lineno}")
-            print()
-
-if failures:
-    print(f"##vso[task.logissue type=warning]Found {failures} syntax error(s)")
-    print(f"##vso[task.complete result=Failed;]Found {failures} syntax error(s)")
diff --git a/.codecov.yml b/.codecov.yml
index 7c8e50e..2097f9d 100644
--- a/.codecov.yml
+++ b/.codecov.yml
@@ -12,5 +12,5 @@ coverage:
 comment:
   layout: "diff, flags"
   branches:
-    - master
+    - main
   after_n_builds: 3
diff --git a/.github/workflows/codeql.yml b/.github/workflows/codeql.yml
index 641322d..2151c42 100644
--- a/.github/workflows/codeql.yml
+++ b/.github/workflows/codeql.yml
@@ -2,9 +2,9 @@ name: "CodeQL"
 
 on:
   push:
-    branches: [ "master" ]
+    branches: ["main"]
   pull_request:
-    branches: [ "master" ]
+    branches: ["main"]
   schedule:
     - cron: "22 2 * * 3"
 
@@ -20,7 +20,7 @@ jobs:
     strategy:
       fail-fast: false
       matrix:
-        language: [ javascript, python ]
+        language: [javascript, python]
 
     steps:
       - name: Checkout
diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
index a150b05..9cef1d9 100644
--- a/.pre-commit-config.yaml
+++ b/.pre-commit-config.yaml
@@ -1,7 +1,11 @@
+ci:
+  autoupdate_schedule: quarterly
+  skip: [pip-compile]
+
 repos:
 # Syntax validation and some basic sanity checks
 - repo: https://github.com/pre-commit/pre-commit-hooks
-  rev: v4.5.0
+  rev: v5.0.0
   hooks:
   - id: check-merge-conflict
   - id: check-ast
@@ -12,8 +16,8 @@ repos:
   - id: check-yaml
 
 # Linting, sorting and formatting
-- repo: https://github.com/charliermarsh/ruff-pre-commit
-  rev: v0.3.3
+- repo: https://github.com/astral-sh/ruff-pre-commit
+  rev: v0.7.2
   hooks:
     - id: ruff
       args: [--fix, --exit-non-zero-on-fix]
@@ -23,8 +27,21 @@ repos:
 # Remember to change versions in .azure-pipelines/azure-pipelines.yml to match
 # the versions here.
 - repo: https://github.com/pre-commit/mirrors-mypy
-  rev: v1.9.0
+  rev: v1.13.0
   hooks:
   - id: mypy
     files: 'dials_data/.*\.py$'
     additional_dependencies: ['types-PyYAML==6.0.12', 'types-requests==2.31.0']
+
+- repo: https://github.com/astral-sh/uv-pre-commit
+  rev: 0.4.30
+  hooks:
+    - id: pip-compile
+      args: [pyproject.toml, -q, -o, requirements.txt]
+      files: ^(pyproject.toml|requirements(_dev|_doc)?.txt)$
+    - id: pip-compile
+      args: [pyproject.toml, -q, --extra, test, -o, requirements_dev.txt]
+      files: ^(pyproject.toml|requirements(_dev|_doc)?.txt)$
+    - id: pip-compile
+      args: [pyproject.toml, -q, --extra, doc, -o, requirements_doc.txt]
+      files: ^(pyproject.toml|requirements(_dev|_doc)?.txt)$
diff --git a/dials_data/cli.py b/dials_data/cli.py
index eb75a69..6dd5f96 100644
--- a/dials_data/cli.py
+++ b/dials_data/cli.py
@@ -119,7 +119,7 @@ def main():
         version = dials_data.__version__ + "-dev"
     parser = argparse.ArgumentParser(
         usage="dials.data <command> [<args>]",
-        description="""DIALS regression data manager v{version}
+        description=f"""DIALS regression data manager v{version}
 
 The most commonly used commands are:
    list     List available datasets
@@ -128,7 +128,7 @@ def main():
 Each command has its own set of parameters, and you can get more information
 by running dials.data <command> --help
 
-""".format(version=version),
+""",
         formatter_class=argparse.RawTextHelpFormatter,
     )
     parser.add_argument("subcommand", help=argparse.SUPPRESS)
diff --git a/dials_data/datasets.py b/dials_data/datasets.py
index 2fe193a..42549ab 100644
--- a/dials_data/datasets.py
+++ b/dials_data/datasets.py
@@ -134,11 +134,7 @@ def list_known_definitions(ds_list, quiet=False) -> None:
             size_information = "unverified dataset"
         else:
             size_information = _human_readable(get_resident_size(shortname))
-        print(
-            "{shortname}: {dataset[name]} ({size_information})".format(
-                shortname=shortname, dataset=dataset, size_information=size_information
-            )
-        )
+        print(f"{shortname}: {dataset['name']} ({size_information})")
         print(
             "{indent}{author} ({license})".format(
                 author=dataset.get("author", "unknown author"),
@@ -147,7 +143,7 @@ def list_known_definitions(ds_list, quiet=False) -> None:
             )
         )
         if dataset.get("url"):
-            print("{indent}{dataset[url]}".format(indent=indent, dataset=dataset))
+            print(f"{indent}{dataset['url']}")
         print(
             "\n{}\n".format(
                 textwrap.fill(
diff --git a/dials_data/download.py b/dials_data/download.py
index dcb26c9..15798e6 100644
--- a/dials_data/download.py
+++ b/dials_data/download.py
@@ -10,7 +10,7 @@
 import warnings
 import zipfile
 from pathlib import Path
-from typing import Any, Optional, Union
+from typing import Any
 from urllib.parse import urlparse
 
 import py.path
@@ -104,7 +104,7 @@ def fetch_dataset(
     read_only: bool = False,
     verbose: bool = False,
     pre_scan: bool = True,
-) -> Union[bool, dict[str, Any]]:
+) -> bool | dict[str, Any]:
     """Check for the presence or integrity of the local copy of the specified
     test dataset. If the dataset is not available or out of date then attempt
     to download/update it transparently.
@@ -280,7 +280,7 @@ class DataFetcher:
     """
 
     def __init__(self, read_only: bool = False, verify: bool = True):
-        self._cache: dict[str, Optional[Path]] = {}
+        self._cache: dict[str, Path | None] = {}
         self._target_dir: Path = dials_data.datasets.repository_location()
         self._read_only: bool = read_only and os.access(self._target_dir, os.W_OK)
         self._verify: bool = verify
@@ -332,7 +332,7 @@ def __call__(self, test_data: str, pathlib=None, **kwargs):
             return self.result_filter(result=py.path.local(self._cache[test_data]))
         return self.result_filter(result=self._cache[test_data])
 
-    def _attempt_fetch(self, test_data: str) -> Optional[Path]:
+    def _attempt_fetch(self, test_data: str) -> Path | None:
         if self._read_only:
             hashinfo = fetch_dataset(test_data, pre_scan=True, read_only=True)
         else:
diff --git a/pyproject.toml b/pyproject.toml
index 570febd..dec8455 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -23,13 +23,12 @@ classifiers = [
 ]
 keywords = ["dials", "dials_data"]
 dynamic = ["readme"]
-requires-python = ">=3.8"
-dependencies = [
-    "importlib_resources>=1.1,!=6.2,!=6.3.0,!=6.3.1",
-    "pytest",
-    "pyyaml",
-    "requests",
-]
+requires-python = ">=3.9"
+dependencies = ["pyyaml", "requests", "py", "importlib_resources~=6.3"]
+
+[project.optional-dependencies]
+test = ["coverage", "pytest"]
+doc = ["Sphinx~=6.2", "sphinx_rtd_theme~=1.3"]
 
 [project.urls]
 Homepage = "https://github.com/dials/data"
@@ -38,64 +37,18 @@ Documentation = "https://dials-data.readthedocs.io/"
 "Source Code" = "https://github.com/dials/data"
 
 [project.entry-points]
-"libtbx.dispatcher.script" = { "dials.data" = "dials.data" }
 "libtbx.precommit" = { dials_data = "dials_data" }
 pytest11 = { dials_data = "dials_data.pytest11" }
 
 [project.scripts]
 "dials.data" = "dials_data.cli:main"
 
-[tool.setuptools]
-include-package-data = true
-zip-safe = false
-license-files = ["LICENSE"]
-
-[tool.setuptools.packages]
-find = { namespaces = false }
-
-[tool.setuptools.package-data]
-dials_data = ["py.typed"]
-
 [tool.setuptools.dynamic]
 readme = { file = ["README.rst", "HISTORY.rst"], content-type = "text/x-rst" }
 
 [tool.ruff.lint]
-# Black disagrees with flake8 on a few points. Ignore those.
-# E203 whitespace before ':'
-# E266 too many leading '#' for block comment
-# E501 line too long
-ignore = ["E203", "E266", "E501"]
-
-select = [
-    "E401",
-    "E711",
-    "E712",
-    "E713",
-    "E714",
-    "E721",
-    "E722",
-    "F401",
-    "F402",
-    "F403",
-    "F405",
-    "F541",
-    "F631",
-    "F632",
-    "F633",
-    "F811",
-    "F821",
-    "F822",
-    "F841",
-    "F901",
-    "W191",
-    "W291",
-    "W292",
-    "W293",
-    "W605",
-    "C4",
-]
-# For converting to pyproject/ruff, only duplicate isort. Can add more later.
-fixable = ["I"]
+ignore = ["E501"]
+select = ["E", "F", "I", "C4"]
 
 [tool.ruff.lint.isort]
 required-imports = ["from __future__ import annotations"]
diff --git a/requirements.txt b/requirements.txt
index b196687..b5f06fe 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1,5 +1,18 @@
-importlib_resources==6.0.1
+# This file was autogenerated by uv via the following command:
+#    uv pip compile pyproject.toml -o requirements.txt
+certifi==2024.8.30
+    # via requests
+charset-normalizer==3.4.0
+    # via requests
+idna==3.10
+    # via requests
+importlib-resources==6.4.5
+    # via dials-data (pyproject.toml)
 py==1.11.0
-pytest==7.4.2
+    # via dials-data (pyproject.toml)
 pyyaml==6.0.1
+    # via dials-data (pyproject.toml)
 requests==2.31.0
+    # via dials-data (pyproject.toml)
+urllib3==2.2.3
+    # via requests
diff --git a/requirements_dev.txt b/requirements_dev.txt
index e947538..ff4db0a 100644
--- a/requirements_dev.txt
+++ b/requirements_dev.txt
@@ -1,7 +1,28 @@
+# This file was autogenerated by uv via the following command:
+#    uv pip compile pyproject.toml --extra test -o requirements_dev.txt
+certifi==2024.8.30
+    # via requests
+charset-normalizer==3.4.0
+    # via requests
 coverage==7.3.1
-importlib_resources==6.3.2
+    # via dials-data (pyproject.toml)
+idna==3.10
+    # via requests
+importlib-resources==6.4.5
+    # via dials-data (pyproject.toml)
+iniconfig==2.0.0
+    # via pytest
+packaging==24.1
+    # via pytest
+pluggy==1.5.0
+    # via pytest
 py==1.11.0
+    # via dials-data (pyproject.toml)
 pytest==7.4.2
+    # via dials-data (pyproject.toml)
 pyyaml==6.0.1
+    # via dials-data (pyproject.toml)
 requests==2.31.0
-wheel==0.41.2
+    # via dials-data (pyproject.toml)
+urllib3==2.2.3
+    # via requests
diff --git a/requirements_doc.txt b/requirements_doc.txt
index bcdb491..6908463 100644
--- a/requirements_doc.txt
+++ b/requirements_doc.txt
@@ -1,5 +1,61 @@
+# This file was autogenerated by uv via the following command:
+#    uv pip compile pyproject.toml --extra doc -o requirements_doc.txt
+alabaster==0.7.16
+    # via sphinx
+babel==2.16.0
+    # via sphinx
+certifi==2024.8.30
+    # via requests
+charset-normalizer==3.4.0
+    # via requests
+docutils==0.18.1
+    # via
+    #   sphinx
+    #   sphinx-rtd-theme
+idna==3.10
+    # via requests
+imagesize==1.4.1
+    # via sphinx
+importlib-resources==6.4.5
+    # via dials-data (pyproject.toml)
+jinja2==3.1.4
+    # via sphinx
+markupsafe==3.0.2
+    # via jinja2
+packaging==24.1
+    # via sphinx
 py==1.11.0
-pytest==7.4.2
+    # via dials-data (pyproject.toml)
+pygments==2.18.0
+    # via sphinx
 pyyaml==6.0.1
-Sphinx==6.2.1
-sphinx_rtd_theme==1.3.0
+    # via dials-data (pyproject.toml)
+requests==2.32.3
+    # via
+    #   dials-data (pyproject.toml)
+    #   sphinx
+snowballstemmer==2.2.0
+    # via sphinx
+sphinx==6.2.1
+    # via
+    #   dials-data (pyproject.toml)
+    #   sphinx-rtd-theme
+    #   sphinxcontrib-jquery
+sphinx-rtd-theme==1.3.0
+    # via dials-data (pyproject.toml)
+sphinxcontrib-applehelp==2.0.0
+    # via sphinx
+sphinxcontrib-devhelp==2.0.0
+    # via sphinx
+sphinxcontrib-htmlhelp==2.1.0
+    # via sphinx
+sphinxcontrib-jquery==4.1
+    # via sphinx-rtd-theme
+sphinxcontrib-jsmath==1.0.1
+    # via sphinx
+sphinxcontrib-qthelp==2.0.0
+    # via sphinx
+sphinxcontrib-serializinghtml==2.0.0
+    # via sphinx
+urllib3==2.2.3
+    # via requests