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PIP likelihood is -Inf when the MSA has gap-only column #33

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junniest opened this issue Feb 14, 2025 · 0 comments
Open

PIP likelihood is -Inf when the MSA has gap-only column #33

junniest opened this issue Feb 14, 2025 · 0 comments
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Currently the PIP likelihood is -Inf when the MSA contains a gap-only column. Mathematically this is correct but meaningless, and ultimately no alignments should contain such columns. Implement filter on reading the MSA to remove gap-only cols.
@junniest junniest self-assigned this Feb 14, 2025
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