Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Annotations to anatomy terms P6.p, P7.p and P8.p #2

Open
rankishore opened this issue Oct 15, 2015 · 3 comments
Open

Annotations to anatomy terms P6.p, P7.p and P8.p #2

rankishore opened this issue Oct 15, 2015 · 3 comments

Comments

@rankishore
Copy link

Annotations to anatomy term P6.p are problematic because when computed on, one cannot arrive at it's vulval or non-vulval nature; Annotations need to be changed to either 'P6.p hermaphrodite' or 'P6.p male', depending on the context in the paper.
Affects gene tissue-expression, gene regulation and phenotype data.

@kyook
Copy link
Member

kyook commented Oct 15, 2015

Looking at the postgres app tables (allele phenotype), there are 21 annotations that with P6.p as an anatomy annotation; 9/21 are concurrently annotated with a larval life stage. The default for all 21 annotations is that they are for hermaphrodites. 2/21 of the annotations are to hermaphrodite specific terms (e.g., vulval cell fate specification and VPC cell division variant).

In addition to using male specific anatomy terms, phenotype sex-based anatomy discrimination is and can be supported by using the
*lifestage ontology (e.g., adult male (WBls:0000056), L4 larval male Ce (WBls:0000073))
*male specific phenotype terms - male behavior variant (WBPhenotype:0000888) and male physiology variant (WBPhenotype:0000928), male tail development variant (WBPhenotype:0001297)

If male specific cell lineages were included in the anatomy ontology, I should think that would be the cleanest way forward.

@draciti
Copy link

draciti commented Oct 19, 2015

Please note this is true for all VPCs (p3.p-p8.p) not just P6.p -as stated above

@draciti
Copy link

draciti commented Oct 19, 2015

From Wen

  1. Classes with Pn.p entry:

Expr_pattern (Daniela will look up them)
Interaction (via #GR_condition -> Anatomy_term) (Xiaodong will look up them)

Anatomy_function (5 objects for Raymond):
Anatomy_function : "WBbtf0053"
Anatomy_function : "WBbtf0054"
Anatomy_function : "WBbtf0146"
Anatomy_function : "WBbtf0147"
Anatomy_function : "WBbtf0234"

WBProcess (1 object for Karen):
WBProcess : "WBbiopr:00000020"

  1. Classes with Anatomy_term tag but no entry for Pn.p:

Condition
Expression_cluster
GO_term
Paper
Strain (via #Phenotype_info -> Anatomy_term)
Variation (via #Phenotype_info -> Anatomy_term)
Transgene (via #Phenotype_info -> Anatomy_term)
RNAi (via #Phenotype_info -> Anatomy_term)

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Projects
None yet
Development

No branches or pull requests

3 participants