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[PA165964265] Bad GPML for Valproic Acid Pathway, Pharmacokinetics #74

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pharmgen opened this issue Mar 30, 2018 · 0 comments
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pharmgen commented Mar 30, 2018

Latest GPML for pathwayPA165964265 is obsolete.
Use this instead: PA165964265-new.gpml

Note that even the updated GPML has errors that must be fixed:

  • 'IVD' [id:b5da5]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • 'hepatoxicity' [id:a0039]: Missing PharmGKB Accession ID.
  • 'hepatoxicity' [id:a0039]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • 'hepatoxicity' [id:a0039]: BlackBox should be converted to Phenotype or Process.
  • 'glutathione' [id:cc24c]: Missing PharmGKB Accession ID.
  • 'glutathione' [id:cc24c]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • 'ECH1' [id:cfa30]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • 'HSD17B1' [id:f7d4c]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • 'ACADSB' [id:bd34a]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • 'Detoxification' [id:d263c]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • '4-ene valproic acid-coenzyme A' [id:d6f88]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • 'valproic acid-coenzyme A' [id:b9e7f]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • '2,4-diene valproic acid-coenzyme A' [id:b6b8e]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • '2-ene valproic acid-coenzyme A' [id:ad695]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • '3-ene valproic acid-coenzyme A' [id:f9a72]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • '3-oh valproic acid-coenzyme A' [id:b3f30]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • 'c3-coenzyme A' [id:b4899]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • 'c5-coenzyme A' [id:f3217]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • '3-oxo-valproic acid-coenzyme A' [id:ce65e]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • 'thiol conjugates of valproic acid' [id:a59b2]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • '2,3-diene valproic acid-coenzyme A' [id:f47cb]: Cellular location is 'Intracellular' but it's in a Mitochondria.
  • Biochemical Reaction line [id:b2238] (from 'glutathione' [id:cc24c] to 'thiol conjugates of valproic acid' [id:a59b2]): Missing evidence.
  • Activation line [id:a0aaf] (from 'thiol conjugates of valproic acid' [id:a59b2] to 'Detoxification' [id:d263c]): Missing evidence.
  • Activation line [id:cc0b5] (from '4-ene valproic acid' [id:d5a27] to 'hepatoxicity' [id:a0039]): Missing evidence.
@pharmgen pharmgen added this to the Update GPML milestone Mar 30, 2018
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