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- Welcome to the Huberman Lab podcast
where we discuss science
and science-based tools
for everyday life.
I'm Andrew Huberman and I'm a professor
of neurobiology and ophthalmology
at Stanford School of Medicine.
Today we are discussing fitness.
Fitness, of course,
is vitally important for
cardiovascular health,
for strength, for endurance,
for lifespan, for healthspan.
I can't think of anyone out
there that wouldn't want to
have healthy hormonal function,
healthy cardiovascular
function, to live a long time
and to feel vital,
that is to have a long healthspan as well
as a long lifespan.
Fitness and fitness
protocols are tremendously
powerful for developing all of that.
However, despite there
being an enormous amount
of information out there on
the internet and in books
and elsewhere, it can
be a bit overwhelming.
So today's episode is really designed
to synthesize science based
tools that we've covered
on the podcast, some
with expert guests like
Dr. Andy Galpin or Dr.
Peter Attia, or world
renowned Movement specialist Ido Portal,
or physiotherapist and strength
and conditioning coach, Jeff Cavaliere.
We've had all of them as
guests on the podcast,
and each and every one
of them provided a wealth
of knowledge in terms
of the various things
that you can do to optimize very specific
or multiple aspects of fitness.
Today, we're going to do
something a little bit
different than usual.
Typically on the Huberman Lab podcast,
I offer mechanism upfront or first,
and then we talk about
protocols that you can use
that really lean on those science
and science based mechanisms.
Today I'm going to describe
a specific protocol
that serves as a general
template that anyone, in fact,
everyone can use in order to maximize all
aspects of fitness.
So that includes endurance,
strength, flexibility,
hypertrophy, aesthetic changes, et cetera.
However, this general
framework can also be modified,
that is customized to
your particular needs.
So if you're somebody
who really wants to build
more strength or bigger muscles,
you can change the
protocol and the overall
program according to that.
And I'll talk about very
specific ways to do that.
Or if you're somebody
who really just wants
to maintain strength, but
you want to build endurance,
we'll talk about that.
And of course, we will
cover real life issues,
such as should you train
if you are sleep deprived,
what about food?
When should you eat?
What if you haven't
eaten and you're hungry?
Should you still train?
Et cetera, et cetera.
We're going to cover all of that, again,
in the context of this,
what I would call foundational
template of fitness.
Now, this foundational template of fitness
is something that I personally use.
In fact, I've used it
for over three decades,
hard to believe that I'm that old,
but I just recently
turned 47, and I still use
this basic protocol or
template across the week
and modify it according to
what my particular goals
are that year, that month, even that day,
because I, like you,
live in the real world
and sometimes I've been traveling
or I miss a workout, yes,
it does happen, or life
isn't organized in exactly
the way that I need to in
order to have everything
go according to the
protocol that's on paper.
So we're going to
discuss real world issues
and how to work with the
real world issues in order
to get the most out of
your fitness program.
And again, by the end of today's
program, I can assure you,
you will have a template
protocol that you can build
up from, build out, change and modify,
and that will really serve
your fitness goals according
to the science and what
peer-reviewed studies
and the experts that
appeared on this podcast
and other podcasts really
tell us is best and optimal
for our fitness.
I'm pleased to announce that
the Huberman Lab podcast
has now launched a premium channel.
I want to be very clear that
the Huberman Lab podcast
will continue to be released
every Monday at zero cost
to consumer, and there will
be no change in the format
of these podcasts.
The premium channel is a
response to the many questions
we get about specific topics,
and it will allow me to really drill deep
into specific answers
related to those topics.
So once a month, I'm going
to host and ask me anything,
so-called AMA, where
you can ask me anything
about specific topics
covered on the Huberman Lab
podcast and I will answer those questions.
Those of course will be recorded.
They will also be other
premium content available
to premium subscribers such as transcripts
and short videos of new
tools and unique tools
for mental health, physical
health and performance.
If you want to check
out the premium channel,
you can go to hubermanlab.com/premium.
There is a $10 a month
charge or $100 per year,
and I should mention that a large portion
of the proceeds from the
Huberman Lab Premium Channel
will go to support scientific
research that develops
the very sorts of tools that we talk
about on the Huberman Lab podcast.
The rest of the support
for the Huberman Lab Podcast
premium channel will go
to supporting the regular
Huberman Lab podcast.
Again, that's hubermanlab.com/premium.
Before we dive into today's
content about fitness
and fitness protocols, I want
to tell you about a brand
new study that is very exciting
and frankly very unusual.
This is a study that was published
out of the University
of Houston, examining
what I would call a micro
exercise or a micro movement.
It's a very small movement
of a very small portion
of your body, in fact, just
1% of your musculature,
that when it's performed
continuously while seated has,
at least what they
report, are very dramatic
positive changes in terms of blood sugar
utilization and metabolism.
So the title of this study
is "A potent physiological
method to magnify and sustain
soleus oxidative
metabolism improves glucose
and lipid regulation."
This study was published in iScience,
and as I mentioned earlier,
it is getting a lot of
attention and it's very unusual.
Without going into all
the details of this study,
let me just briefly give you a little bit
of the background.
First of all, you have a
muscle called the soleus.
The soleus muscle is a more
or less wide flat muscle
that sits beneath what most
people think of as their calf,
although it's part of the calf muscle.
The other portion of the calf
is called the gastrocnemius.
The soleus sits below that.
Now, the soleus muscle is a unique muscle
because it's largely slow
twitch muscle fibers.
It's designed to be used continuously
over and over again for
stabilizing your body
when you're standing upright, for walking.
This is a muscle that's
designed to contract
over and over and over again.
In fact, you could walk
all day on this muscle
and most likely it would not get sore.
You probably done that
and it did not get sore.
In contrast, a muscle like
your bicep or your tricep,
if I were to have you
perform hundreds or thousands
of repetitions, even
with a very lightweight
one pound weight or a two pound weight,
eventually it would fatigue.
You would feel a sort of a burn there.
It's a very unusual set of
muscles to use repeatedly.
But the soleus is an unusual
muscle in that it really
is designed to be used continuously.
Now, this study was focused
on how people who sit a lot
of the day and don't have
the opportunity for a lot
of physical movement or
maybe who don't even exercise
at all can improve their metabolism
and glucose utilization.
Without going into a deep dive
about glucose utilization,
because we've done the
deep dive on this podcast,
episodes such as metabolism, et cetera,
you can look those up at hubermanlab.com.
They're all timestamped
and available there.
Anytime you eat, your blood
sugar goes up to some extent.
So your blood glucose, as it's called,
goes up to some extent.
And then insulin is a hormone that's used
to essentially chaperone
and sequester and use
that blood glucose or
it's basically the idea
is you don't want blood
glucose to go too high.
Hyperinsulinemia is something associated
with blood glucose that's
too high because insulin goes
up to essentially match
the level of blood glucose.
You don't also don't
want to be hypoglycemic,
you don't want to have
blood sugar that's too low,
and insulin is involved
in both regulating peaks
and troughs in blood sugar, blood glucose.
So we can basically say,
and this is very simple,
but we can basically say
that you don't want blood
glucose to be elevated
too much or for too long.
That's not good.
In fact, people who have
diabetes because they don't
make insulin, people who
have type 1 diabetes do not
make insulin at all, their blood glucose
is so high that they
actually have to take insulin
in order to regulate otherwise
their blood glucose can
go so high that it can damage
cells and damage organs.
It can even kill people.
People who have type 2 diabetes are
so called insulin insensitive.
They make insulin, but the
receptors to insulin are
not sensitive to it,
and so they make more insulin
than normally would be
made and blood glucose
isn't regulated properly,
et cetera, et cetera.
The take home message about blood glucose
is that you want your blood
glucose levels to go up
when you eat, but not too
high and you don't want them
to stay elevated for too long.
This study looked at how
people who are largely
sedentary or at least sitting
can increase the utilization,
the clearance of glucose from
the bloodstream after eating,
and they also looked
at overall metabolism.
For people, get this,
that were using just that
1% of muscle, the soleus,
by doing what they call a soleus pushup.
So the soleus pushup can
be described very simply
as if you're sitting
down with your knee bent
at approximately right
angle, like a square corner,
and pushing up, or I should
say lifting your heel
while pushing down on
your toe and contracting
the calf muscle as it were,
and then lowering the
heel and then in lifting
that heel again, lowering the
heel, lifting the heel again,
each one of those is what
they call a soleus pushup.
This study had people
continuously do soleus pushups
and they looked at things like
blood glucose utilization,
they looked at metabolism and so on.
Now, a couple of important
things about this study
before I tell you what they discovered,
which was frankly pretty miraculous,
almost hard to believe,
and yet I believe the data
looked to be collected
quite well, and there
are a lot of statistics
and the study looks to be quite thorough.
First of all, they used
an equal number of male
and female subjects.
There were a wide range of
body mass indices, okay?
So this wasn't just super
fit people or people
that were purely sedentary and not fit.
They used a wide variety
of ages, time of day,
people who tended to walk
a lot or not walk a lot.
They measured changes
in metabolism and blood
glucose utilization and
people that had done
these soleus pushups while
seated in the laboratory,
and I must say,
they had them do these
soleus pushups for quite
a long while, continuously.
So they had them do it
for as long as 270 minutes
total throughout the day.
So if you divide that,
that's four and a half hours,
you might say, well,
four and a half hours of
lifting the heel and putting
the heel down, lifting the
heel, putting the heel down,
that's a lot.
But they didn't always do it continuously.
They had some breaks in there.
So this is the sort of
thing that you could imagine
you or other people could do while seated,
while doing Zooms or
while on calls or maybe
even while eating, doing
that sort of thing.
Although I'm not suggesting
that you constantly
be focusing on soleus
pushups throughout your life.
The point is that people
who did these soleus
pushups experienced dramatic
improvements in blood
sugar regulation and in
metabolism despite the fact
that the soleus is just 1%
of the total musculature.
So here I'm going to
read from the abstract
about what they found,
people who did these soleus pushups,
despite being a tiny muscle and using very
little local energy...
In fact, they measured muscle glycogen,
the burn or essentially
the utilization of fuel
within the muscle, and
there was very little
utilization of fuel
within the soleus itself,
and that's because the soleus
has this unique property
of needing to basically
keep you going all day,
walking all day or moving all day.
What they saw was a large
magnitude, for example,
52% less postprandial,
that's after a meal,
glucose excursion,
So 52% less increase in
blood glucose and 60%,
six zero less hyper insulinemia,
so reduced levels of insulin.
They also, miraculously,
observed that despite this being,
again, a small muscle, 1%
of the total muscle mass,
so very small oxidative use,
they saw big improvements in
systemic metabolic regulation.
So this is interesting
and I think something
that we should at least know about.
I'm not aware that anyone's
replicated this study yet.
I know there's a ton of
excitement about this study
in the popular press, and if
the data turn out to hold up,
which I like to imagine they will,
I can understand why
there's so much excitement.
What this means is that if
you're somebody who cares
about blood glucose regulation,
you want to keep your metabolism running,
please don't stop exercising,
the other ways that you exercise.
But if you're somebody who
wants to maximize your health,
doing these soleus pushups
fairly continuously
while seated is going to be beneficial.
And in addition to that,
I know that there are going
to be people out there who,
for instance, might be
injured or you're traveling
and you're stuck on a plane
or you're in the classroom
and you're forced to study
all day or take notes all day.
You're just not getting
enough opportunity to get
those steps that you want to take,
whether or that's 10,000 or fewer or more,
getting enough steps or movement.
Maybe you don't have time
to get out and do your run,
or maybe you're also running,
weightlifting and doing
yoga classes and things
of that sort, but you want to
further improve your fitness,
at least in terms of
your metabolic health.
This seems like a terrific,
very low investment way to do it.
Certainly zero cost.
It does take a little bit of attention,
so you have to divert
your attention from other
things you're doing to
make sure that you're still
doing these soleus pushups.
I'm sure that many of you
are going to have a lot
of detailed questions such
as how high did they lift
the heel and did they contract
the muscle very hard or not?
Couple of things about that,
they did not have subjects
really contract the muscle hard.
They did measure the angle of heel raise
and it was anywhere from 10 to 15 degrees
so they didn't have to go way,
way up on their tippy toes
or things of that sort.
In any event, 270 minutes,
four and a half hours of
doing these soleus pushups
is a lot, but by my read of the data
and the rather significant,
or I should say very significant effects
that they observed on
blood glucose regulation
and metabolism, et cetera,
seems to me that doing less
would still be beneficial
and that you don't necessarily
have to do the full
270 minutes in order to get the benefits
that they observed.
More about the study includes the fact
that the benefits they observed
were very long lasting,
as long as two hours after a meal,
they could still see this improved
blood glucose utilization.
I don't know because I wasn't able to find
it in the methods whether
or not they were doing
the soleus pushups while
they were consuming blood
sugar in this study.
The point being that if
you're somebody who cares
about their fitness, this
study is interesting,
because what it means is that, again,
if you are forced to be
immobile or sitting longer
than you would like,
if you're stuck in a meeting or Zooms
or class or on a plane, et cetera,
or if you're simply trying to add a bit
more fitness and metabolic
health to your overall regimen,
soleus pushups, at least to me,
seem like a very low investment, simple,
zero cost tool to improve
your metabolic health.
For those of you that
want to peruse the study
in more detail, we will provide a link
to this paper published in iScience
in the show note caption.
Before we begin, I'd like to emphasize
that this podcast is
separate from my teaching
and research roles at Stanford.
It is however, part of my
desire and effort to bring
zero cost to consumer
information about science
and science related tools
to the general public.
In keeping with that theme,
I'd like to thank the
sponsors of today's podcast.
Our first sponsor is InsideTracker.
InsideTracker is a
personalized nutrition platform
that analyzes data from
your blood and DNA to help
you better understand your
body and help you meet
your health goals.
Now, I've long been a
believer in getting regular
blood work done for the
simple reason that many
of the factors that impact your immediate
and long-term health can only be analyzed
from a quality blood test.
One issue with a lot of
blood tests and DNA tests
out there, however, is that
you get information back
about hormones, blood lipids, et cetera,
but you don't know what to
do with that information.
InsideTracker makes
understanding all of that very
easy and even better points
to specific directives,
that is things you can do
in terms of your lifestyle,
your nutrition,
supplementation, et cetera,
in order to bring those numbers related
to metabolic factors,
lipids, hormones, et cetera,
into the ranges that are optimal for you,
your immediate and long-term health.
If you'd like to try InsideTracker,
you can go to insidetracker.com/huberman
to get 20% off any of InsideTracker plans.
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to get 20% off.
Today's episode is also
brought to us by ROKA.
ROKA makes eyeglasses
and sunglasses that are
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The company was founded by
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and sunglasses were designed
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I've spent a lifetime
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I don't wear sunglasses
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Today's episode is also
brought to us by Helix Sleep.
Helix Sleep makes mattresses and pillows
that are customized to
your unique sleep needs.
Now, sleep is the fundamental layer
that is the most important
aspect of mental health,
physical health and performance.
I've said that before on this podcast,
and I'm going to be saying
it over and over again.
If you're sleeping well,
everything else is better,
and if you're not sleeping well,
everything else gets far worse.
So sleep is vital,
and sleeping on the correct
mattress is absolutely vital.
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The Huberman Lab podcast is now partnered
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To find the supplements we discuss
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you can go to live
Momentous spelled O-U-S,
livemomentous.com/huberman,
and I should just mention that the library
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Again, that's livemomentous.com/huberman.
Let's talk about fitness and let's talk
about how you can develop
the optimal fitness
protocols for you.
So that includes what to
do each day of the week
and your fitness protocol across the week,
and indeed across the month and the year
and even year to year.
When we had Dr. Andy
Galpin on the podcast,
he said something very
important that we want to keep
in mind today, which is concepts
are few, methods are many,
that is there are an
infinite number of different
programs and exercises
and set and rep schemes
and different runs and burpees
and pushups, et cetera,
et cetera that one can follow.
However, there are really
just a few basic concepts
or principles of muscle physiology,
of cardiovascular function,
of connective tissue
function that provide or set the basis
for the adaptations that we call fitness
or that lead to fitness.
So I'm going to list those off now.
We can talk about a fitness
protocol that's really
aimed mainly toward developing skill.
That's one. Or speed.
That's another.
Or power, which is speed times strength,
or specifically strength, or hypertrophy,
growth of muscles, or endurance
such as muscular endurance.
Muscular endurance is, for instance,
your ability to stay in
a plank position or to do
a wall sit, to sit on an
invisible chair against a wall,
or other forms of endurance like near
pure anaerobic endurance.
So a one minute sprint or
less or a one minute all
out cycling on stationary
bike, this sort of thing,
or endurance that occurs
in the kind of 3 to 12
minute total duration range.
So that might be sprints or high intensity
interval type training.
It could be an all out swim,
it could be all out row.
That's another form of endurance,
taps into different fuel systems,
different aspects of muscle
physiology, et cetera.
And then endurance that
lasts 30 minutes or more,
which is typically what people think
about when they think about endurance.
But of course, the other
forms of endurance matter.
So we've got skill, speed,
power, strength, hypertrophy,
muscular endurance, anaerobic endurance,
what I would call 3 to
12 minute endurance,
although it goes by other names as well,
and 30 minutes or more endurance type
exercise and adaptations.
Each and every one of these
requires different principles,
different concepts in order to improve,
say your muscular strength
or your hypertrophy or both.
However, there's a general
theme that sits beneath
all adaptations leading to fitness,
and that's what we're
really going to set down
as the base layer,
the foundation of everything
we talk about today.
And that's that we need
to think about what are
the modifiable variables?
Again, I'm borrowing
directly from the episode
with Dr. Andy Galpin.
He was the one that said,
modifiable variables are the
key thing to think about.
What are you going to modify?
What are you going to change
in order to increase one
or some of the various things
I listed off before, skill,
speed, power, strength,
hypertrophy, endurance,
et cetera, et cetera.
And some of the key concepts that emerge
from that discussion are
that we need to think
about progressive overload.
Normally when people hear
about progressive overload,
they think about adding more
weight to a bar or picking
up heavier dumbbells,
but that could also be
progressive overload in
the context of running up
a hill of steeper incline
or running a little bit
faster or a little bit further
and so on and so forth.
Now, as I promised earlier,
today we are not going to
drill into each and every one
of the mechanisms that
underlie the different
adaptations that are
going to develop speed
and strength and endurance, et cetera,
because that was covered in the podcast
with Dr. Andy Galpin and the other podcast
with experts that I mentioned earlier.
And we again, will provide
links to those podcasts
if you want to drill
into those mechanisms.
Instead, what we are going
to do is we're going to start
with a program that
essentially is designed
for you to maximize all aspects of fitness
to the extent that you can
simultaneously maximize
all aspects of fitness,
but then to change or modify that protocol
so that if you want to
build up more, for instance,
strength and you want to
just hold onto the endurance
you have, you don't
want to build endurance,
at least not in that week or
that month, you can do that.
Or if you want to improve your endurance
while maintaining your
strength, you can do that.
And so on and so forth.
Most people, I do believe,
would like a combination
of strength and endurance
and flexibility and
maybe even hypertrophy,
particularly for certain
muscle groups that maybe are
not as well developed
as other muscle groups.
They want to bring
balance to their physique,
both for sake of aesthetics
and for sake of health
and for sake of general functioning,
to maybe even to eliminate pain,
the protocol that I'm going
to describe really works
as a foundational
template for that as well.
So let's drill into that
foundational protocol
and I'll keep referring to it
as the foundational protocol,
not because it's the one that I use,
although it is the one that I use,
and not because it's the
one that we're talking
about today, although
it's the one we're talking
about today, but because
we need some general
framework from which to build out the more
specific protocols that
we'll get into in a bit
more detail later.
So in this foundational
protocol for fitness,
what you'll notice is
that on any one given day,
you're going to focus on one
particular aspect of fitness.
Maybe it's endurance, maybe it's strength,
maybe it's hypertrophy, in particular,
it might be hypertrophy for
a particular muscle group
or muscle groups.
That said, across the entire week,
it's designed to bring
fitness and different forms
of fitness to all aspects of your body.
So this particular protocol begins
on Sunday, although that's
simply the day that I happen
to begin the protocol.
And again, this protocol is not important
because it's the one that I follow.
I follow it because it is important.
In other words, it's a
protocol that's really gleaned
from the scientific
literature and the experts,
that is for you.
So this fitness protocol
is really about you.
I just may refer to it as
the one that I follow simply