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can I use ArchR for single cell ChIP-seq? #13

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sotuamax opened this issue May 20, 2024 · 0 comments
Open

can I use ArchR for single cell ChIP-seq? #13

sotuamax opened this issue May 20, 2024 · 0 comments

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@sotuamax
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Hi,

I am aware of that the ArchR package was developed primarily for the analysis of large scale scATAC-seq. Just out of curiosity, if this package is appropriate for the analysis of single cell ChIP-seq data. For example, for single cell ChIP-seq intentionally to capture a specific transcription factor binding sites? the genome-wide tile matrix can be even sparser compared to scATAC-seq.

Many thanks!

Best,
Meiyuan

@sotuamax sotuamax changed the title can I use ArchR for single cell ChIP-seq data like Transcription Factor binding site, or for single cell histone modification data (H3K4me)? can I use ArchR for single cell ChIP-seq? May 20, 2024
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