README.md

Bridge RNA Designer

A web interface for designing Bridge RNAs for Bridge Editing.

References

Durrant, M.G., Perry, N.T., Pai, J.J. et al. Bridge RNAs direct programmable recombination of target and donor DNA. Nature 630, 984-993 (2024). https://doi.org/10.1038/s41586-024-07552-4

Hiraizumi, M., Perry, N.T., Durrant, M.G. et al. Structural mechanism of bridge RNA-guided recombination. Nature 630, 994–1002 (2024). https://doi.org/10.1038/s41586-024-07570-2

Webtool

Published app

Run locally

streamlit run app.py --server.address=0.0.0.0

CLI

See BridgeRNADesigner